A protein that is a translation product of the cyp51 gene in Mycobacterium tuberculosis H37Rv. [PRO:DNx, UniProtKB:P9WPP9]
EC 1.14.14.154;
CYPLI;
Cytochrome P450 51;
Cytochrome P450-14DM;
Cytochrome P450-LIA1;
Sterol 14-alpha demethylase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| clotrimazole | Mycobacterium tuberculosis H37Rv | Kd | 0.2000 | 1 | 1 |
| econazole | Mycobacterium tuberculosis H37Rv | Kd | 0.2000 | 1 | 1 |
| fluconazole | Mycobacterium tuberculosis H37Rv | Kd | 33.4000 | 3 | 3 |
| miconazole | Mycobacterium tuberculosis H37Rv | Kd | 0.2000 | 1 | 1 |
| estriol | Mycobacterium tuberculosis H37Rv | Kd | 100.0000 | 1 | 1 |
| 4,4'-Dihydroxybenzophenone | Mycobacterium tuberculosis H37Rv | Kd | 28.0000 | 1 | 1 |
| 4(5)-phenylimidazole | Mycobacterium tuberculosis H37Rv | Kd | 1.3000 | 1 | 1 |