An ATP-binding cassette sub-family C member 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q92887]
ATP-binding cassette sub-family C member 2;
Canalicular multidrug resistance protein;
Multidrug resistance-associated protein 2;
7.6.2.2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| melatonin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pyrazinamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 1-(3-chlorophenyl)piperazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tacrine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acetaminophen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acetazolamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| albendazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| albuterol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alprenolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diatrizoic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aminoglutethimide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| theophylline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amiodarone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dan 2163 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amitriptyline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amlexanox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amlodipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amoxapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amsacrine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| anastrozole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| anthralin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| antipyrine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aspirin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| astemizole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atenolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| azathioprine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| baclofen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| benzbromarone | Homo sapiens (human) | IC50 | 41.6000 | 1 | 1 |
| benzocaine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bicalutamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bay h 4502 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bisacodyl | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bromopride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bronopol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| busulfan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| caffeine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| verapamil | Homo sapiens (human) | IC50 | 112.6667 | 3 | 3 |
| carbamazepine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carmustine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carprofen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carvedilol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| celecoxib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorambucil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlordiazepoxide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chloroquine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorpheniramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorpromazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorpropamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorthalidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorzoxazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cifenline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciglitazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cilostazol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cimetidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciprofloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| citalopram | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clioquinol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clobazam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clofazimine | Homo sapiens (human) | IC50 | 10.4000 | 1 | 1 |
| clofibrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clomiphene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clomipramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dapsone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| desipramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diazoxide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dipyridamole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| disopyramide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| disulfiram | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| domperidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| donepezil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| doxepin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ebastine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enoxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ethacrynic acid | Homo sapiens (human) | IC50 | 3.8500 | 1 | 1 |
| ethosuximide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| brl 42810 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 4-biphenylylacetic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| felodipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fenofibrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fleroxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flucytosine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flumazenil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluorescite | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluorouracil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluoxetine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flutamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| furosemide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gliclazide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| glipizide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| guanfacine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| haloperidol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydrochlorothiazide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydroflumethiazide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydroxyurea | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lidocaine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ifosfamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| imipramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amrinone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indapamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indomethacin | Homo sapiens (human) | IC50 | 235.0000 | 1 | 1 |
| iohexol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| iproniazid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isoniazid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isradipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| itraconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketanserin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketoconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lansoprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| leflunomide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lofepramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lomustine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| loratadine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| maprotiline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mebendazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mefenamic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metformin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metoclopramide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metoprolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metronidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mexiletine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| minoxidil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mirtazapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| moclobemide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acecainide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nadolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nalidixic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nefazodone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nefopam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| neostigmine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nevirapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nicardipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nifedipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nimesulide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nimodipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nisoldipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitrazepam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| norfloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nortriptyline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ofloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| omeprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ondansetron | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxaprozin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxybutynin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| papaverine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pemoline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pentamidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pentoxifylline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| perphenazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| phenacetin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pindolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piracetam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piribedil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ono 1078 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pyranoprofen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| praziquantel | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| primaquine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| primidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| probenecid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| probenecid | Homo sapiens (human) | Ki | 42.2000 | 1 | 1 |
| procainamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| prochlorperazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| procyclidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| promethazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| propafenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| propranolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ranitidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| riluzole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| risperidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rofecoxib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfadiazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sotalol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| imatinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vorinostat | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfamethoxazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfisoxazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sumatriptan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gatifloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tazarotene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| temozolomide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terazosin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terbutaline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terfenadine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thiotepa | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tiapride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tilorone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tinidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tizanidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nikethamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tolbutamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tolnaftate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| triamterene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trimethoprim | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thenoyltrifluoroacetone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| undecylenic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| urapidil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| venlafaxine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vigabatrin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pirinixic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ici 204,219 | Homo sapiens (human) | IC50 | 58.8000 | 1 | 1 |
| zaleplon | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zonisamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zopiclone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| prednisolone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| reserpine | Homo sapiens (human) | IC50 | 68.4000 | 1 | 1 |
| reserpine | Homo sapiens (human) | Ki | 295.0000 | 1 | 1 |
| carbon tetrachloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vincristine | Homo sapiens (human) | Ki | 802.0000 | 1 | 1 |
| ethinyl estradiol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tubocurarine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| apomorphine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| kanamycin a | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levodopa | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| colchicine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| triamcinolone diacetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cytarabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| medroxyprogesterone acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| triamcinolone acetonide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| methylprednisolone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rotenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| phenformin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aminophylline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| galantamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| procarbazine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| betamethasone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| emetine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dimenhydrinate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 1-naphthylisothiocyanate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| megestrol acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| erythromycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydroxychloroquine sulfate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levonorgestrel | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vinblastine | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| ethambutol hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metylperon | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| stavudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dicloxacillin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cladribine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metocurine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etidronate disodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zalcitabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| camptothecin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mafenide acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diacerein | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| selegiline hydrochloride, (r)-isomer | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thiamphenicol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pancuronium bromide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ornidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| danazol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| daunorubicin | Homo sapiens (human) | Ki | 49.4000 | 1 | 1 |
| fludarabine phosphate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| benzonidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amoxicillin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| timolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indoramin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxcarbazepine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carbidopa | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zidovudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| feprazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tobramycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| paclitaxel | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etoposide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etoposide | Homo sapiens (human) | Ki | 756.0000 | 1 | 1 |
| ribavirin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amikacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diltiazem | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vecuronium bromide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitazoxanide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acarbose | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lorcainide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| captopril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| staurosporine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| foscarnet sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atracurium besylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nicorandil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pergolide mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefadroxil anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| talniflumate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fenoldopam mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefaclor anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pefloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefotetan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lovastatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flupirtine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enoximone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| stepronin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| simvastatin | Homo sapiens (human) | IC50 | 79.0000 | 2 | 2 |
| idazoxan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| remoxipride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cabergoline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atomoxetine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mifepristone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| salmeterol xinafoate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| finasteride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| imiquimod | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sertindole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| adapalene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aromasil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sparfloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zileuton | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cidofovir anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gemcitabine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aripiprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atorvastatin calcium anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lamivudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| duloxetine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valsartan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zolmitriptan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| adefovir dipivoxil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| emtricitabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| paroxetine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bupropion hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| doxazosin mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| efavirenz | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nelfinavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mevastatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bupivacaine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| plerixafor | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amprenavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ticlopidine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| epirubicin hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pazufloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| repaglinide | Homo sapiens (human) | IC50 | 72.3000 | 1 | 1 |
| telmisartan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| miconazole nitrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zoledronic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| artemisinin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| brinzolamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| artemether | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| uk 68798 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hp 873 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| loxapine succinate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| voriconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| betamipron | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| doripenem | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tamiflu | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bexarotene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| s20098 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flunisolide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketorolac tromethamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clarithromycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nicotine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lopinavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| moxifloxacin hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fulvestrant | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mizoribine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sr141716 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| racecadotril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tadalafil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| plavix | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clofarabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pramipexole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valdecoxib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mk 0663 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gefitinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| desloratadine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| methotrexate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulbactam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| abiraterone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| febuxostat | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lexapro | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| docetaxel anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levofloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ezetimibe | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cox 189 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| xamoterol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| naproxen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| telbivudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atropine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| erlotinib | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| scutellarin | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| etravirine | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| ramelteon | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| deferasirox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bms204352 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tolvaptan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lenalidomide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lacosamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vincaleukoblastine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vincristine sulfate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| wortmannin | Homo sapiens (human) | IC50 | 46.1000 | 1 | 1 |
| bortezomib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ritonavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| quinidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| meropenem | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| digitoxin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| saquinavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| perindopril erbumine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| miglitol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rocuronium bromide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| linezolid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ochratoxin a | Homo sapiens (human) | IC50 | 58.0000 | 1 | 1 |
| pemirolast potassium salt | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| eplerenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ao 128 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| loteprednol etabonate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluticasone propionate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tretinoin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tacrolimus | Homo sapiens (human) | IC50 | 40.3000 | 1 | 1 |
| mupirocin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zithromax | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| decitabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| teniposide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valrubicin | Homo sapiens (human) | IC50 | 64.0000 | 1 | 1 |
| melphalan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| posaconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rubitecan | Homo sapiens (human) | IC50 | 60.5000 | 1 | 1 |
| arginine vasopressin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trilostane | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| leuprolide acetate | Homo sapiens (human) | IC50 | 80.2000 | 1 | 1 |
| propylthiouracil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levosulpiride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| eszopiclone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| methimazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cinnarizine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| epalrestat | Homo sapiens (human) | IC50 | 84.4000 | 1 | 1 |
| drotaverin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tamoxifen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fusidic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valinomycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hmr 3647 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| maraviroc | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| toremifene citrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nelarabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gestodene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| orlistat | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| quinine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| azilect | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dasatinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sitagliptin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| quercetin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| calcitriol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chrysoeriol | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| alprostadil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vitamin d 2 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pulmicort | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxymetholone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| eprosartan | Homo sapiens (human) | IC50 | 57.9000 | 1 | 1 |
| brompheniramine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dexchlorpheniramine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mycophenolate mofetil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| entacapone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diosmetin | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| myricetin | Homo sapiens (human) | IC50 | 22.0000 | 1 | 1 |
| sdz psc 833 | Homo sapiens (human) | Ki | 28.9000 | 1 | 1 |
| l 660,711 | Homo sapiens (human) | IC50 | 37.0000 | 4 | 4 |
| l 660,711 | Homo sapiens (human) | Ki | 19.7500 | 2 | 2 |
| travoprost | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tranilast | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etretinate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isotretinoin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketotifen fumarate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dinoprost tromethamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rosuvastatin calcium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terbinafine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cyclosporine | Homo sapiens (human) | IC50 | 17.9940 | 5 | 5 |
| cyclosporine | Homo sapiens (human) | Ki | 11.2700 | 3 | 3 |
| natamycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levetiracetam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nalmefene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| naloxone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| topiramate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| demycarosylturimycin h | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acipimox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atosiban | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bimatoprost | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| latanoprost | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nateglinide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| molsidomine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| butorphanol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefixime | Homo sapiens (human) | IC50 | 89.4000 | 1 | 1 |
| lisinopril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ramipril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indinavir sulfate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enalapril maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enalaprilat anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pregabalin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alvimopan anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| famotidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cci 15641 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tenofovir disoproxil fumarate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dexbrompheniramine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifaximin | Homo sapiens (human) | IC50 | 15.4000 | 1 | 1 |
| everolimus | Homo sapiens (human) | IC50 | 11.3000 | 1 | 1 |
| cefpodoxime proxetil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluphenazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitrofurantoin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| roxithromycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefdinir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bisoprolol, fumarate (1:1) salt | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| artesunate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etoposide phosphate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciclesonide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| temsirolimus | Homo sapiens (human) | IC50 | 17.6000 | 1 | 1 |
| dutasteride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vildagliptin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sgd 301-76 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluvoxamine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thioacetazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dexlansoprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gemifloxacin mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rivaroxaban | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hki 272 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tofacitinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pazopanib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ko 143 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| cefotaxime sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alisporivir | Homo sapiens (human) | IC50 | 18.0000 | 1 | 1 |
| dactolisib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rabeprazole sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bivalirudin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| somatostatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ly-146032 | Homo sapiens (human) | IC50 | 29.1000 | 1 | 1 |
| warfarin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pravastatin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alendronate sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mk 0571 | Homo sapiens (human) | IC50 | 20.7000 | 1 | 1 |
| sl 80.0750 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mesna | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piperacillin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxacillin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefazolin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| azlocillin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tak-875 | Homo sapiens (human) | IC50 | 2.4100 | 1 | 1 |
| gs-9451 | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| tetracycline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piroxicam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| roquinimex | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mobiflex | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isoxicam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| minocycline hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tigecycline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lornoxicam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dolutegravir | Homo sapiens (human) | IC50 | 95.0000 | 2 | 2 |
| entecavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acyclovir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifampin | Homo sapiens (human) | IC50 | 53.0000 | 1 | 1 |
| clozapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dacarbazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| didanosine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ganciclovir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valtrex | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| olanzapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| raltitrexed | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| allopurinol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| citrovorum factor | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifapentine | Homo sapiens (human) | IC50 | 16.3000 | 1 | 1 |
| sildenafil citrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aprepitant | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tegaserod maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifabutin | Homo sapiens (human) | IC50 | 49.8000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| p-aminohippuric acid | Homo sapiens (human) | Km | 880.0000 | 1 | 1 |
| vinblastine | Homo sapiens (human) | Km | 137.3000 | 1 | 1 |
| etoposide | Homo sapiens (human) | Km | 616.5400 | 1 | 1 |
| E3040 glucuronide | Homo sapiens (human) | Km | 14.1000 | 1 | 1 |
| estradiol-17 beta-glucuronide | Homo sapiens (human) | Km | 8.3000 | 2 | 2 |
| scy-635 | Homo sapiens (human) | INH | 150.0000 | 1 | 1 |
This protein enables 11 target(s):
| Target | Category | Definition |
|---|---|---|
| protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
| ATP binding | molecular function | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732] |
| organic anion transmembrane transporter activity | molecular function | Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. [GOC:ai] |
| ABC-type xenobiotic transporter activity | molecular function | Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). [EC:7.6.2.2] |
| bilirubin transmembrane transporter activity | molecular function | Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile. [GOC:ai, ISBN:0198547684] |
| ABC-type glutathione S-conjugate transporter activity | molecular function | Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out). [GOC:jl, PMID:1455517, RHEA:19121] |
| ATP hydrolysis activity | molecular function | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. [RHEA:13065] |
| ATPase-coupled transmembrane transporter activity | molecular function | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. [GOC:mtg_transport, ISBN:0815340729] |
| xenobiotic transmembrane transporter activity | molecular function | Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:go_curators, GOC:krc] |
| ATPase-coupled inorganic anion transmembrane transporter activity | molecular function | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in). [GOC:mlg] |
| ABC-type transporter activity | molecular function | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. [PMID:26517899] |
This protein is located in 4 target(s):
| Target | Category | Definition |
|---|---|---|
| plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| cell surface | cellular component | The external part of the cell wall and/or plasma membrane. [GOC:jl, GOC:mtg_sensu, GOC:sm] |
| apical plasma membrane | cellular component | The region of the plasma membrane located at the apical end of the cell. [GOC:curators] |
| intercellular canaliculus | cellular component | An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates. [ISBN:0721662544] |
This protein is active in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| apical plasma membrane | cellular component | The region of the plasma membrane located at the apical end of the cell. [GOC:curators] |
This protein is involved in 13 target(s):
| Target | Category | Definition |
|---|---|---|
| xenobiotic metabolic process | biological process | The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc] |
| xenobiotic transmembrane transport | biological process | The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:ai, GOC:bf, GOC:krc] |
| negative regulation of gene expression | biological process | Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| bile acid and bile salt transport | biological process | The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] |
| bilirubin transport | biological process | The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc] |
| heme catabolic process | biological process | The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. [GOC:jl] |
| xenobiotic export from cell | biological process | The directed movement of a xenobiotic from a cell, into the extracellular region. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:go_curators, GOC:krc] |
| transmembrane transport | biological process | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. [GOC:dph, GOC:jid] |
| transepithelial transport | biological process | The directed movement of a substance from one side of an epithelium to the other. [GOC:mah, GOC:yaf, ISBN:0716731363] |
| leukotriene transport | biological process | The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. [GOC:mah] |
| monoatomic anion transmembrane transport | biological process | The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom. [GOC:dos, GOC:vw] |
| transport across blood-brain barrier | biological process | The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier. [GOC:aruk, GOC:bc, PMID:29377008] |
| xenobiotic transport across blood-brain barrier | biological process | The directed movement of a xenobiotic through the blood-brain barrier. [PMID:25053619] |