Page last updated: 2024-12-05

trimyristin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Trimyristin is a triglyceride composed of three myristate (myristic acid) molecules esterified to a glycerol molecule. It is a white, waxy solid found in nutmeg and is the main component of nutmeg butter. Trimyristin is often used as a starting material for the synthesis of myristic acid, which has various applications in the food, cosmetic, and pharmaceutical industries. Research on trimyristin focuses on its potential applications in these industries, including its use as a biofuel and its potential health benefits, such as anti-inflammatory and antioxidant properties. It is also studied for its potential role in the development of new drug delivery systems.'

trimyristin : A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by myristic (tetradecanoic) acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11148
CHEBI ID77391
SCHEMBL ID112641
MeSH IDM0111540

Synonyms (75)

Synonym
myristic acid triglyceride
dynasan 114
glyceryl trimyristate
555-45-3
tetradecanoic acid,2,3-propanetriyl ester
vp 114
nsc4062
trimyristin
myristin, tri-
myristin
glycerol trimyristate
nsc-4062
tetradecanoic acid, 1,2,3-propanetriyl ester
2,3-di(tetradecanoyloxy)propyl tetradecanoate
glyceryl trimyristate, >=99%
T-6800
trimyristoylglycerol
1,2,3-tritetradecanoyl-rac-glycerol
G0088
LMGL03012616
1,2,3-tri-myristoyl-glycerol
tg(14:0/14:0/14:0)
1,2,3-tritetradecanoyl-sn-glycerol
1,2,3-tritetradecanoyl-glycerol
tg(42:0)
S9209
ai3-18153
18l31psr28 ,
1,2,3-propanetriol tritetradecanoate
tetradecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester
einecs 209-099-7
nsc 4062
unii-18l31psr28
FT-0626749
AKOS015899781
1,2,3-tritetradecanoylglycerol
trimyristin [ii]
trimyristin [mi]
trimyristin [inci]
SCHEMBL112641
DUXYWXYOBMKGIN-UHFFFAOYSA-N
2,3-bis(tetradecanoyloxy)propyl myristate
tracylglycerol(14:0/14:0/14:0)
glyceryl tritetradecanoate
tag(42:0)
CHEBI:77391 ,
tag(14:0/14:0/14:0)
propane-1,2,3-triyl tritetradecanoate
tracylglycerol(42:0)
tg 14:0/14:0/14:0
1,2,3-trimyristoylglycerol
myristic triglyceride
tritetradecanoylglycerol
c45h86o6
AC-34679
mfcd00036229
1,3-bis(tetradecanoyloxy)propan-2-yl tetradecanoate
AS-63167
trimyristin, european pharmacopoeia (ep) reference standard
myristin, tri- (8ci)
glycerol tritetradecanoate
1-myristoyl-2-myristoyl-3-myristoyl-glycerol
tri-myristin
1-tetradecanoyl-2-tetradecanoyl-3-tetradecanoyl-glycerol
tritetradecanoin
Q304581
HY-N2511
DTXSID701014651 ,
CCG-270410
beta-1,2,3-tri-tetradecanoyl-glycerol
beta-trimyristin (mmm)
CS-0022782
trimyristin (ii)
dtxcid70810991
SY052068

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Even sodium dodecylsulfate-stabilized D114-SLN did not exert toxic effects."( Cytotoxicity studies of Dynasan 114 solid lipid nanoparticles (SLN) on RAW 264.7 macrophages-impact of phagocytosis on viability and cytokine production.
Kayser, O; Müller, RH; Olbrich, C; Schöler, N; Tabatt, K, 2004
)
0.32

Dosage Studied

ExcerptRelevanceReference
" The pharmacological activity of the protein was evaluated following oral dosage of calcitonin-loaded SLN in rats."( Improving oral absorption of Salmon calcitonin by trimyristin lipid nanoparticles.
Ferreira, DC; Martins, S; Silva, AC; Souto, EB, 2009
)
0.61
" The in vivo pharmacodynamic activity revealed 2-fold increase in antimalarial activity of curcuminoids entrapped in lipid nanoparticles when compared to free curcuminoids at the tested dosage level."( Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment.
Madhusudhan, B; Nayak, AP; Patankar, S; Souto, EB; Tiyaboonchai, W, 2010
)
0.36
"The development of vaccine delivery systems that will remove or reduce the need for repeated dosing has led to the investigation of sustained release systems."( Impact of implant composition of twin-screw extruded lipid implants on the release behavior.
Bobbala, S; Engert, J; Even, MP; Hook, S; Kooi, KL; Winter, G, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
triglycerideAny glyceride resulting from the condensation of all three hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids.
tetradecanoate esterA fatty acid ester obtained by condensation of the carboxy group of tetradecanoic acid (also known as myristic acid) with a hydroxy group of an alcohol or phenol.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (2)

PathwayProteinsCompounds
Triacylglycerol metabolism TG(14:0/14:0/14:0)1412
De Novo Triacylglycerol Biosynthesis TG(14:0/14:0/14:0)511

Research

Studies (45)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (6.67)18.7374
1990's7 (15.56)18.2507
2000's15 (33.33)29.6817
2010's19 (42.22)24.3611
2020's1 (2.22)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 53.48

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index53.48 (24.57)
Research Supply Index3.91 (2.92)
Research Growth Index4.91 (4.65)
Search Engine Demand Index83.16 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (53.48)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (2.08%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other47 (97.92%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]