Page last updated: 2024-08-07 13:27:36
Prostaglandin reductase 1
A prostaglandin reductase 1 that is encoded in the genome of rat. [OMA:P97584, PRO:DNx]
Synonyms
PRG-1;
15-oxoprostaglandin 13-reductase;
1.3.1.48;
Dithiolethione-inducible gene 1 protein;
D3T-inducible gene 1 protein;
DIG-1;
Leukotriene B4 12-hydroxydehydrogenase;
NAD(P)H-dependent alkenal/one oxidoreductase;
1.3.1.7
Research
Bioassay Publications (1)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| irofulven | Rattus norvegicus (Norway rat) | IC50 | 0.0550 | 1 | 1 |
| acylfulvene | Rattus norvegicus (Norway rat) | IC50 | 0.0950 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| irofulven | Rattus norvegicus (Norway rat) | Km | 213.0000 | 1 | 1 |
| acylfulvene | Rattus norvegicus (Norway rat) | Km | 538.0000 | 1 | 1 |