A 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P26281]
EC 2.7.6.3;
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase;
PPPK;
7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase;
HPPK
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| isoguanine | Escherichia coli K-12 | Kd | 7.5000 | 1 | 1 |
| thioguanine anhydrous | Escherichia coli K-12 | Kd | 18.0000 | 1 | 1 |
| guanine | Escherichia coli K-12 | Kd | 38.0000 | 1 | 1 |
| 8-methylguanine | Escherichia coli K-12 | Kd | 18.0000 | 1 | 1 |
| 2-amino-6-hydroxy-8-mercaptopurine | Escherichia coli K-12 | Kd | 130.0000 | 2 | 2 |