e 4031 has been researched along with Sensitivity and Specificity in 3 studies
E 4031: class III anti-arrhythmia agent; structure given in UD
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine (Prozac) was more potent at blocking hERG 1a/1b than 1a channels, yielding a corresponding reduction in the safety margin." | 1.37 | hERG subunit composition determines differential drug sensitivity. ( Abi-Gerges, N; Holkham, H; Jones, EM; Pollard, CE; Robertson, GA; Valentin, JP, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, H | 1 |
| Smith, GL | 1 |
| Orchard, CH | 1 |
| Hancox, JC | 1 |
| Dolderer, JH | 1 |
| Schuldes, H | 1 |
| Bockhorn, H | 1 |
| Altmannsberger, M | 1 |
| Lambers, C | 1 |
| von Zabern, D | 1 |
| Jonas, D | 1 |
| Schwegler, H | 1 |
| Linke, R | 1 |
| Schröder, UH | 1 |
| Abi-Gerges, N | 1 |
| Holkham, H | 1 |
| Jones, EM | 1 |
| Pollard, CE | 1 |
| Valentin, JP | 1 |
| Robertson, GA | 1 |
3 other studies available for e 4031 and Sensitivity and Specificity
| Article | Year |
|---|---|
Acidosis inhibits spontaneous activity and membrane currents in myocytes isolated from the rabbit atrioventricular node.
Topics: Acidosis; Animals; Atrioventricular Node; Calcium Channels, L-Type; Electrophysiology; Hydrogen-Ion | 2009 |
HERG1 gene expression as a specific tumor marker in colorectal tissues.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoembryonic Antigen; Cell Line, Tum | 2010 |
hERG subunit composition determines differential drug sensitivity.
Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line, Transformed; Drug Evaluation, Preclinical; Ether | 2011 |