terbutaline has been researched along with Sensitivity and Specificity in 33 studies
Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg terbutaline, both by Turbuhaler and used as needed, in addition to regular formoterol in moderate asthma." | 9.10 | Safety of formoterol by Turbuhaler as reliever medication compared with terbutaline in moderate asthma. ( Böszörményi, NG; Ind, PW; Pietinalho, A; Selroos, O; Shiner, RJ; Soliman, S; Villasante, C, 2002) |
| "5 mg terbutaline, both by Turbuhaler and used as needed, in addition to regular formoterol in moderate asthma." | 5.10 | Safety of formoterol by Turbuhaler as reliever medication compared with terbutaline in moderate asthma. ( Böszörményi, NG; Ind, PW; Pietinalho, A; Selroos, O; Shiner, RJ; Soliman, S; Villasante, C, 2002) |
| " The validated method has been successfully applied to the human pharmacokinetic study of R-bambuterol involving 10 healthy volunteers." | 1.40 | A sensitive LC-MS/MS method for simultaneous determination of R-bambuterol and its active metabolite R-terbutaline in human plasma and urine with application to a clinical pharmacokinetic study. ( Cheng, Q; Liu, S; Tan, W; Xu, L; Zhao, T; Zhou, T, 2014) |
| "Ninety-eight chronic obstructive pulmonary disease (COPD) patients were submitted to a respiratory function test on two different days." | 1.34 | The bronchodilator test in chronic obstructive pulmonary disease: interpretation methods. ( Almagro, P; Heredia, JL; Quintana, S; Rodríguez-Carballeira, M; Rué, M, 2007) |
| " The proposed method enables the unambiguous identification and quantification of tulobuterol for pharmacokinetic, bioavailability or bioequivalence studies." | 1.33 | High-performance liquid chromatography electrospray ionization mass spectrometry determination of tulobuterol in rabbit's plasma. ( Gong, G; Jiao, H; Liang, J; Tian, Y; Xu, F; Zhang, Z, 2005) |
| "Terbutaline is a beta-adrenergic receptor antagonist that acts as a bronchodilator in the treatment of asthma and chronic bronchitis." | 1.32 | Simple determination of terbutaline in dog plasma by column-switching liquid chromatography. ( Zhang, Y; Zhang, ZR, 2004) |
| "The terbutaline was preseparated from the interfering components in urine on Phenomenex silica column and the terbutaline enantiomers and betaxolol were resolved and determined on a Sumichiral OA-4900 chiral stationary phase." | 1.31 | Determination of terbutaline enantiomers in human urine by coupled achiral-chiral high-performance liquid chromatography with fluorescence detection. ( Kim, HJ; Kim, JH; Kim, KH; Shin, SD, 2001) |
| "There is a lack of information concerning analysis of terbutaline sulfate and quantification of its related substances particularly in the liquid dosage forms." | 1.31 | Determination of terbutaline sulfate and its degradation products in pharmaceutical formulations using LC. ( Al-Omari, MM; Badwan, AA; Daraghmeh, N; Jaber, AM; Sara, Z, 2002) |
| " Bronchoconstrictor and bronchodilator responsiveness were assessed with cumulative dose-response curves, using histamine and terbutaline, respectively." | 1.30 | Lack of correlation between bronchoconstrictor response and bronchodilator response in a population-based study. ( de Gooijer, A; Douma, WR; Koëter, GH; Postma, DS; Rijcken, B; Schouten, JP; Weiss, ST, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (24.24) | 18.2507 |
| 2000's | 19 (57.58) | 29.6817 |
| 2010's | 5 (15.15) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, K | 1 |
| Yi, F | 1 |
| Han, L | 1 |
| Liu, B | 1 |
| Zhang, X | 1 |
| Xue, Y | 1 |
| Luo, W | 2 |
| Chen, Q | 1 |
| Abo El Abass Mohamed, S | 1 |
| El-Awady, MI | 1 |
| Zhou, T | 2 |
| Zhao, T | 2 |
| Cheng, Q | 2 |
| Liu, S | 2 |
| Xu, L | 2 |
| Tan, W | 3 |
| Zou, C | 1 |
| Pistolozzi, M | 1 |
| Tan, E | 1 |
| Zheng, L | 1 |
| Tong, P | 1 |
| Zheng, X | 1 |
| Chi, Y | 1 |
| Chen, G | 1 |
| Zhang, L | 1 |
| Chaisuwan, P | 1 |
| Nacapricha, D | 1 |
| Wilairat, P | 1 |
| Jiang, Z | 1 |
| William Smith, N | 1 |
| Li, S | 1 |
| Wang, J | 1 |
| Zhao, S | 1 |
| Zhu, L | 1 |
| Deng, J | 1 |
| Liu, A | 1 |
| Guo, B | 1 |
| Dai, R | 1 |
| Nie, J | 1 |
| Zhu, M | 1 |
| Lian, J | 1 |
| Pan, Y | 1 |
| Deng, X | 1 |
| Hu, C | 1 |
| Ind, PW | 1 |
| Villasante, C | 1 |
| Shiner, RJ | 1 |
| Pietinalho, A | 1 |
| Böszörményi, NG | 1 |
| Soliman, S | 1 |
| Selroos, O | 1 |
| Chen, XY | 1 |
| Yang, HY | 1 |
| Zhong, DF | 1 |
| Xu, HY | 1 |
| Zhang, YF | 1 |
| Zhang, Y | 1 |
| Zhang, ZR | 1 |
| Xu, F | 1 |
| Zhang, Z | 1 |
| Tian, Y | 1 |
| Jiao, H | 1 |
| Liang, J | 1 |
| Gong, G | 1 |
| Almeida, VK | 1 |
| Larive, CK | 1 |
| Rodríguez-Carballeira, M | 1 |
| Heredia, JL | 1 |
| Rué, M | 1 |
| Quintana, S | 1 |
| Almagro, P | 1 |
| Cunliffe, JM | 1 |
| Whorton, MR | 1 |
| Sunahara, RK | 1 |
| Kennedy, RT | 1 |
| Beltagi, AM | 1 |
| El-Desoky, HS | 1 |
| Ghoneim, MM | 1 |
| Deñola, NL | 1 |
| Quiming, NS | 1 |
| Saito, Y | 1 |
| Jinno, K | 1 |
| Collins, S | 1 |
| O'Keeffe, M | 1 |
| Smyth, MR | 1 |
| Van Vyncht, G | 1 |
| Preece, S | 1 |
| Gaspar, P | 1 |
| Maghuin-Rogister, G | 1 |
| DePauw, E | 1 |
| Couper, FJ | 1 |
| Drummer, OH | 1 |
| Large, V | 1 |
| Reynisdottir, S | 1 |
| Eleborg, L | 1 |
| van Harmelen, V | 1 |
| Strömmer, L | 1 |
| Arner, P | 1 |
| Pálmarsdóttir, S | 1 |
| Mathiasson, L | 1 |
| Jönsson, JA | 1 |
| Edholm, LE | 1 |
| Douma, WR | 1 |
| de Gooijer, A | 1 |
| Rijcken, B | 1 |
| Schouten, JP | 1 |
| Koëter, GH | 1 |
| Weiss, ST | 1 |
| Postma, DS | 1 |
| Lu, W | 1 |
| Cole, RB | 1 |
| Kim, KH | 2 |
| Kim, HJ | 2 |
| Kim, JH | 2 |
| Shin, SD | 1 |
| Henze, MK | 1 |
| Opfermann, G | 1 |
| Spahn-Langguth, H | 1 |
| Schänzer, W | 1 |
| Lee, JH | 1 |
| Lee, SC | 1 |
| Nielsen, KG | 1 |
| Bisgaard, H | 1 |
| García-Ruiz, C | 1 |
| Marina, ML | 1 |
| Walker, PS | 1 |
| Petterson, GL | 1 |
| Bondesson, E | 1 |
| Conway, JH | 1 |
| Daraghmeh, N | 1 |
| Al-Omari, MM | 1 |
| Sara, Z | 1 |
| Badwan, AA | 1 |
| Jaber, AM | 1 |
| Noseda, A | 1 |
| Schmerber, J | 1 |
| Prigogine, T | 1 |
| Yernault, JC | 1 |
3 trials available for terbutaline and Sensitivity and Specificity
| Article | Year |
|---|---|
Response to bronchodilator and clinical, pathophysiological features in patients with nonasthmatic eosinophilic bronchitis.
Topics: Administration, Oral; Adult; Airway Remodeling; Asthma; Bronchial Hyperreactivity; Bronchitis; Bronc | 2020 |
Safety of formoterol by Turbuhaler as reliever medication compared with terbutaline in moderate asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Dose-Response Relationship, Drug | 2002 |
Discriminative capacity of bronchodilator response measured with three different lung function techniques in asthmatic and healthy children aged 2 to 5 years.
Topics: Administration, Inhalation; Age Factors; Airway Resistance; Asthma; Bronchodilator Agents; Case-Cont | 2001 |
30 other studies available for terbutaline and Sensitivity and Specificity
| Article | Year |
|---|---|
Spectrofluorimetric investigation with green analytical procedures for estimation of bambuterol and terbutaline: Application to pharmaceutical dosage forms and content uniformity testing.
Topics: Calibration; Green Chemistry Technology; Hydrogen-Ion Concentration; Limit of Detection; Reproducibi | 2019 |
A sensitive LC-MS/MS method for simultaneous determination of R-bambuterol and its active metabolite R-terbutaline in human plasma and urine with application to a clinical pharmacokinetic study.
Topics: Administration, Oral; Biotransformation; Chromatography, Liquid; Drug Stability; Humans; Linear Mode | 2014 |
Simultaneous determination of bambuterol and its two major metabolites in human plasma by hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Linear Model | 2014 |
Electrostacking online sample pre-concentration capillary electrophoresis with amperometric detection for beta2-agonists in human urine.
Topics: Adrenergic beta-Agonists; Albuterol; Clenbuterol; Electrodes; Electrophoresis, Capillary; Ethanolami | 2008 |
Monolithic and packed particle materials for in-line pre-concentration in capillary electrophoresis for 4-hydroxy-3-methoxy-methamphetamine and terbutaline.
Topics: Benzyl Alcohol; Electrophoresis, Capillary; Methamphetamine; Sensitivity and Specificity; Solid Phas | 2008 |
Determination of terbutaline sulfate by capillary electrophoresis with chemiluminescence detection.
Topics: Borates; Electrophoresis, Capillary; Ferricyanides; Humans; Linear Models; Luminescent Measurements; | 2009 |
Simultaneous analysis of bambuterol and its active metabolite terbutaline enantiomers in rat plasma by chiral liquid chromatography-tandem mass spectrometry.
Topics: Animals; Bronchodilator Agents; Calibration; Chromatography, Liquid; Drug Stability; Female; Freezin | 2010 |
[Determination of fifteen beta-agonists in animal urine by high performance liquid chromatography-tandem mass spectrometry].
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chromatography, High Pressure Liquid; Clenbuterol; Sen | 2010 |
[Rapid analysis of terbutaline by combined solid phase extraction/liquid chromatography tandem mass spectrometry].
Topics: Bronchodilator Agents; Chromatography, Liquid; Humans; Male; Quality Control; Sensitivity and Specif | 2001 |
Simple determination of terbutaline in dog plasma by column-switching liquid chromatography.
Topics: Adrenergic beta-Agonists; Animals; Chromatography, High Pressure Liquid; Dogs; Reproducibility of Re | 2004 |
High-performance liquid chromatography electrospray ionization mass spectrometry determination of tulobuterol in rabbit's plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Rabbits; Sensitivity and Specificity; Spectrometry, M | 2005 |
Insights into cyclodextrin interactions during sample stacking using capillary isotachophoresis with on-line microcoil NMR detection.
Topics: Albuterol; Alprenolol; Atenolol; Cyclodextrins; Diffusion; Electrolytes; Electrophoresis; Magnetic R | 2005 |
The bronchodilator test in chronic obstructive pulmonary disease: interpretation methods.
Topics: Aged; Bronchial Provocation Tests; Bronchodilator Agents; Data Interpretation, Statistical; Female; | 2007 |
A CE assay for the detection of agonist-stimulated adenylyl cyclase activity.
Topics: Adenylyl Cyclases; Biological Assay; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Res | 2007 |
Quantification of terbutaline in pharmaceutical formulation and human serum by adsorptive stripping voltammetry at a glassy carbon electrode.
Topics: Adrenergic beta-Agonists; Carbon; Electrochemistry; Electrodes; Glass; Humans; Hydrogen-Ion Concentr | 2007 |
Simultaneous enantioseparation and sensitivity enhancement of basic drugs using large-volume sample stacking.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; beta-Cyclodextrins; Calibration; Carbazoles; Ca | 2007 |
Multi-residue analysis for beta-agonists in urine and liver samples using mixed phase columns with determination by radioimmunoassay.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Clenbuterol; Drug Residues; Indicators and Rea | 1994 |
Gas and liquid chromatography coupled to tandem mass spectrometry for the multiresidue analysis of beta-agonists in biological matrices.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Animals, Domestic; Cattle; Clenbuterol; Drug Residues; | 1996 |
Gas chromatographic-mass spectrometric determination of beta 2-agonists in postmortem blood: application in forensic medicine.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Autopsy; Calibration; Fenoterol; Forensic Medicine; Gas | 1996 |
Lipolysis in human fat cells obtained under local and general anesthesia.
Topics: Abdomen; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Adult; Anesthesia, General; Anesth | 1997 |
Determination of a basic drug, bambuterol, in human plasma by capillary electrophoresis using double stacking for large volume injection and supported liquid membranes for sample pretreatment.
Topics: Bronchodilator Agents; Cholinesterase Inhibitors; Electrophoresis, Capillary; Humans; Hydrogen-Ion C | 1997 |
Lack of correlation between bronchoconstrictor response and bronchodilator response in a population-based study.
Topics: Administration, Inhalation; Adolescent; Adult; Bronchi; Bronchial Hyperreactivity; Bronchial Provoca | 1997 |
Determination of chiral pharmaceutical compounds, terbutaline, ketamine and propranolol, by on-line capillary electrophoresis-electrospray ionization mass spectrometry.
Topics: Cyclodextrins; Electrolytes; Electrophoresis, Capillary; Ketamine; Mass Spectrometry; Propranolol; S | 1998 |
Determination of terbutaline enantiomers in human urine by coupled achiral-chiral high-performance liquid chromatography with fluorescence detection.
Topics: Adrenergic beta-Agonists; Adult; Bronchodilator Agents; Chromatography, High Pressure Liquid; Fluore | 2001 |
Screening of beta-2 agonists and confirmation of fenoterol, orciprenaline, reproterol and terbutaline with gas chromatography-mass spectrometry as tetrahydroisoquinoline derivatives.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Calibration; Drug Combinations; Fe | 2001 |
Determination of the optical purity of (R)-terbutaline by 1H-NMR and RP-LC using chiral derivatizing agent, (S)-(-)-alpha-methylbenzyl isocyanate.
Topics: Adrenergic beta-Agonists; Bronchodilator Agents; Chromatography, High Pressure Liquid; Indicators an | 2001 |
Fast enantiomeric separation of basis drugs by electrokinetic chromatography. Application to the quantitation of terbutaline in a pharmaceutical preparation.
Topics: Albuterol; beta-Cyclodextrins; Bile Acids and Salts; Buffers; Chromatography; Chromatography, Micell | 2001 |
An advanced and detailed in vitro validation procedure for the radiolabeling of carrier-free terbutaline sulphate dry powder.
Topics: Administration, Inhalation; Aerosols; Asthma; Bias; Bronchodilator Agents; Dose-Response Relationshi | 2001 |
Determination of terbutaline sulfate and its degradation products in pharmaceutical formulations using LC.
Topics: Bronchodilator Agents; Calibration; Chromatography, High Pressure Liquid; Pharmaceutical Preparation | 2002 |
Perceived effect on shortness of breath of an acute inhalation of saline or terbutaline: variability and sensitivity of a visual analogue scale in patients with asthma or COPD.
Topics: Asthma; Dyspnea; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Middle | 1992 |