Page last updated: 2024-11-05

oleyl alcohol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

oleyl alcohol: structure; RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5284499
CHEMBL ID2105350
CHEBI ID73504
SCHEMBL ID5668
MeSH IDM0055646

Synonyms (137)

Synonym
cis-octadecen-1-ol
(9z)-octadec-9-en-1-ol
(z)-octadec-9-enol
einecs 205-597-3
genapol o
9-octadecen-1-ol
witcohol 90
ai3-07620
hsdb 6484
(z)-9-octadecen-1-ol
nsc 10999
olive alcohol
witcohol 85
dermaffine
hd oleyl alcohol 70/75
crodacol a.10
adol 340
loxanol 95
lancol
adol 85
sipol o
hd oleyl alcohol 80/85
143-28-2
cis-9-octadecenyl alcohol
unjecol 90
oleyl alcohol
9-octadecen-1-ol, cis-
unjecol 110
oleo alcohol
unjecol 50
h.d. eutanol
novol
hd-ocenol 90/95
ocenol
hd oleyl alcohol cg
hd-ocenol k
cachalot o-3
adol 320
nsc-10999
nsc10999
unjecol 70
loxanol m
0leyl alcohol
cis-9-0ctadecen-1-ol
hd oleyl alcohol 90/95
satol
atalco o
9-octadecen-1-ol, (z)-
adol 90
oleic alcohol
crodacol-o
oleoyl alcohol
adol 330
cachalot o-8
adol 80
adol 34
cis-9-octadecen-1-ol
cachalot o-15
siponol oc
cachalot o-1
oceol
oleol
conditioner 1
witcohol 85 (tn)
oleyl alcohol (nf)
D05245
oleyl alcohol, >=99% (gc)
oleyl alcohol, technical grade, 85%
NCGC00164365-01
3164D881-7E14-4979-9E60-58DDC0468323
O0058
LMFA05000213
9z-octadecen-1-ol
AKOS004910411
NCGC00164365-02
(z)-octadec-9-en-1-ol
172f2wn8dv ,
oleyl alcohol [nf]
ec 205-597-3
unii-172f2wn8dv
cis-oleyl alcohol
dtxcid502010
dtxsid0022010 ,
cas-143-28-2
tox21_200111
NCGC00257665-01
fema no. 4363
CHEMBL2105350
chebi:73504 ,
z-9-dodecen-1-ol
(z)-9-octadecenol
cis-9-octadecenol
(9z)-9-octadecen-1-ol
cis-9-octadecenol [fhfi]
oleyl alcohol [usp-rs]
oleyl alcohol [inci]
oleyl alcohol [ii]
oleyl alcohol [who-dd]
oleyl alcohol [mart.]
oleyl alcohol [vandf]
oleyl alcohol [ep monograph]
oleyl alcohol [ep impurity]
oleyl alcohol [mi]
SCHEMBL5668
(z)-octadeca-9-en-1-ol
cis 9 octadecen-1-ol
( z)-9-octadecenol
unjecol 90nr
hd-eutanol
octadec-9-en-1-ol, (z)-
(9z)-9-octadecen-1-ol #
octadec-9z-enol
octadeca-9-cis-en-1-ol
unjecol 90n
cis-.delta.9-octadecenol
W-109512
mfcd00002993
oleyl alcohol, technical, ~60% (gc)
oleyl alcohol, analytical standard
oleyl alcohol, united states pharmacopeia (usp) reference standard
9(z)-octadecen-1-ol
lipocol o
francol oa-95
hd-echelon 90/95
anjecol 90n
cis-laquo deltaraquo 9-octadecenol
fancol oa-95
anjecol 90nr
Q7086489
cis-octadec-9-en-1-ol
(9z)-9-octadecen-1-ol, 85per cent
A884989
BS-42539
EN300-21584642
CS-0181666
HY-141573
oleyl alcohol, tech grade

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"Oleyl alcohol was complexed with new amphiphilic polyvinylalcohol derivatives with the aim of increasing its aqueous solubility, thus improving bioavailability and favoring its antitumor activity."( Enhancement of oleyl alcohol anti tumor activity through complexation in polyvinylalcohol amphiphilic derivatives.
Bergamante, V; Carosio, R; Fini, A; Montaldo, PG; Orienti, I; Zuccari, G, 2007
)
0.34
" Eighteen organic solvents were screened to determine their biocompatibility, and bioavailability for their effects on Klebsiella pneumoniae growth."( In situ recovery of 2,3-butanediol from fermentation by liquid-liquid extraction.
Anvari, M; Khayati, G; Pahlavanzadeh, H; Vasheghani-Farahani, E, 2009
)
0.35

Dosage Studied

ExcerptRelevanceReference
" The results showed that, before reaching a maximum, the increase of ferulic acid concentration, temperature, or enzyme dosage led to an increase in volumetric productivity."( Lipase-catalyzed esterification of ferulic Acid with oleyl alcohol in ionic liquid/isooctane binary systems.
Chen, B; Guo, Z; Huang, J; Liu, H; Wang, M; Xu, X; Zheng, L, 2011
)
0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
nonionic surfactantA surfactant with an uncharged hydrophilic headgroup.
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
long-chain primary fatty alcoholA long-chain fatty alcohol in which the hydroxy group is attached to a methylene (CH2) group.
fatty alcohol 18:1Any fatty alcohol containing 18 carbons and 1 double bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
GLI family zinc finger 3Homo sapiens (human)Potency76.88060.000714.592883.7951AID1259369
AR proteinHomo sapiens (human)Potency5.48870.000221.22318,912.5098AID743063
pregnane X nuclear receptorHomo sapiens (human)Potency31.11480.005428.02631,258.9301AID1346982; AID720659
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1446872Inhibition of recombinant HIV-1 group M subtype B RT-RNase H activity expressed in Escherichia coli M15 using 18-nucleotide 3'-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5'-dabsyl-labeled DNA as substrate measured after 1 hr2017European journal of medicinal chemistry, Apr-21, Volume: 130Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase.
AID1446873Inhibition of wild-type HIV1 RT associated RNA dependent DNA polymerase activity using poly(A) template/oligo(dT) primer after 30 mins by picogreen staining based method2017European journal of medicinal chemistry, Apr-21, Volume: 130Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (64)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (14.06)18.7374
1990's11 (17.19)18.2507
2000's18 (28.13)29.6817
2010's19 (29.69)24.3611
2020's7 (10.94)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (1.52%)5.53%
Reviews2 (3.03%)6.00%
Case Studies6 (9.09%)4.05%
Observational0 (0.00%)0.25%
Other57 (86.36%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]