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oxyphenbutazone and Sensitivity and Specificity

oxyphenbutazone has been researched along with Sensitivity and Specificity in 3 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Oxyphenbutazone in the sample was found to be present at a level below the quantification level of 10."1.32Analysis of adulterants in a traditional herbal medicinal product using liquid chromatography-mass spectrometry-mass spectrometry. ( Holmes, MJ; Koh, HL; Lau, AJ; Woo, SO, 2003)
" Mean +/- SEM elimination half-life was 13."1.30Pharmacokinetics of phenylbutazone in camels. ( Abdel Hadi, AH; Boni, NS; Wasfi, IA; Zorob, O, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lau, AJ1
Holmes, MJ1
Woo, SO1
Koh, HL1
Wasfi, IA1
Abdel Hadi, AH1
Zorob, O1
Boni, NS1
Grippa, E1
Santini, L1
Castellano, G1
Gatto, MT1
Leone, MG1
Saso, L1

Other Studies

3 other studies available for oxyphenbutazone and Sensitivity and Specificity

ArticleYear
Analysis of adulterants in a traditional herbal medicinal product using liquid chromatography-mass spectrometry-mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2003, Feb-26, Volume: 31, Issue:2

    Topics: Caffeine; Chromatography, Liquid; Drug Contamination; Herbal Medicine; Mass Spectrometry; Oxyphenbut

2003
Pharmacokinetics of phenylbutazone in camels.
    American journal of veterinary research, 1997, Volume: 58, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Camelus; Chromatography, High Pressure Liquid; Dos

1997
Simultaneous determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and oxyphenbutazone in equine serum by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, Jan-28, Volume: 738, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pre

2000