1-methyl-3-isobutylxanthine has been researched along with Sensitivity and Specificity in 5 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Herrerías, JM | 2 |
| Esteban, JM | 1 |
| Caballero-Plasencia, AM | 1 |
| Valenzuela-Barranco, M | 1 |
| Motilva, V | 1 |
| Alarcón, C | 1 |
| Martín, J | 1 |
| Esteban, P | 1 |
| Bingham, J | 1 |
| Sudarsanam, S | 1 |
| Srinivasan, S | 1 |
| Jones, LG | 1 |
| Bastepe, M | 1 |
| Ashby, B | 1 |
5 other studies available for 1-methyl-3-isobutylxanthine and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Preventive effect of zaprinast and 3-isobutyl, 1-methylxanthine (phosphodiesterase inhibitors) on gastric injury induced by nonsteroidal antiinflammatory drugs in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Disease M | 2003 |
Profiling human phosphodiesterase genes and splice isoforms.
Topics: 1-Methyl-3-isobutylxanthine; Alternative Splicing; Calcium; Calmodulin; Cyclic AMP; Cyclic GMP; Enzy | 2006 |
Inhibition of cyclic AMP accumulation by endothelin is pertussis toxin sensitive and calcium independent in isolated adult feline cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Antagonists | 1996 |
Identification of a region of the C-terminal domain involved in short-term desensitization of the prostaglandin EP4 receptor.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell | 1999 |