Proteins > karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b
Page last updated: 2024-08-07 19:55:28

karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (54)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
acridoneHomo sapiens (human)EC5049.120010
praziquantelHomo sapiens (human)EC50500.000010
yohimbine hydrochlorideHomo sapiens (human)EC50500.000010
4-fluorobenzamideHomo sapiens (human)EC50500.000010
9-methoxyacridineHomo sapiens (human)EC5013.520010
2-chlorothioxanthen-9-oneHomo sapiens (human)EC50108.100010
6-methyl-2-[4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-3-quinolinecarbonitrileHomo sapiens (human)EC5015.960010
2-[(5,6-dimethyl-4-oxo-3-phenyl-2-thieno[2,3-d]pyrimidinyl)thio]-N-(2-furanylmethyl)acetamideHomo sapiens (human)EC50500.000010
1H-indazole-3-carboxylic acid methyl esterHomo sapiens (human)EC5053.160010
6,6,7-trimethyl-1-(4-morpholinyl)-3-(phenylmethylthio)-5,8-dihydro-2,7-naphthyridine-4-carbonitrileHomo sapiens (human)EC50121.500010
4-chlorobenzoic acid 2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl esterHomo sapiens (human)EC503.725010
1-(4-methylphenyl)spiro[1,3-diazinane-5,4'-2,3,3a,5-tetrahydro-1H-pyrrolo[1,2-a]quinoline]-2,4,6-trioneHomo sapiens (human)EC5073.110010
N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-thiophen-2-ylacetamideHomo sapiens (human)EC5095.880010
5,6-dimethyl-N-(3-pyridinylmethyl)-4-thieno[2,3-d]pyrimidinamineHomo sapiens (human)EC50500.000010
N-(2-furanylmethyl)-1-(4-methoxyphenyl)-5-benzimidazolamineHomo sapiens (human)EC50500.000010
sclareolideHomo sapiens (human)EC50500.000010
N-[3-cyano-4-(4-methoxyphenyl)-5-methyl-2-thiophenyl]-2-methyl-3-pyrazolecarboxamideHomo sapiens (human)EC50500.000010
1-cyclopropyl-4-[4-(trifluoromethyl)phenyl]-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)EC5019.140010
3-[oxo-[4-(2-phenylethyl)-1-piperazinyl]methyl]-1-benzopyran-2-oneHomo sapiens (human)EC507.336010
2-[[4-cyano-6,6,7-trimethyl-1-(4-morpholinyl)-5,8-dihydro-2,7-naphthyridin-3-yl]thio]acetic acid methyl esterHomo sapiens (human)EC5063.540010
7-methyl-2-[4-(4-methylphenyl)sulfonyl-1,4-diazepan-1-yl]-3-quinolinecarbonitrileHomo sapiens (human)EC5027.920010
7-methoxy-2-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]-3-quinolinecarbonitrileHomo sapiens (human)EC50500.000010
1-[2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl]-3-phenylureaHomo sapiens (human)EC5012.600010
3-cyclohexyl-2-hydrazinyl-7-(phenylmethyl)-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-4-oneHomo sapiens (human)EC500.918110
4-(4-chlorophenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)EC5013.190010
3-acetyl-7-methoxycoumarinHomo sapiens (human)EC5034.610010
5-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethoxy]-2-[(3-methylphenyl)methyl]-3,4-dihydroisoquinolin-1-oneHomo sapiens (human)EC50120.500010
N-[4-[(3-bromo-5-methoxy-4-prop-2-enoxyphenyl)methylamino]-2-methoxyphenyl]-2-methylpropanamideHomo sapiens (human)EC50500.000010
2-[4-(4-chlorophenyl)-2-thiazolyl]ethanethioamideHomo sapiens (human)EC50500.000010
5-(dimethylsulfamoyl)-N-(diphenylmethyl)-2-(1-pyrrolidinyl)benzamideHomo sapiens (human)EC50500.000010
5-methyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-thieno[2,3-d]pyrimidinamineHomo sapiens (human)EC50500.000010
4-chloro-3-(diethylsulfamoyl)-N-(2-nitrophenyl)benzamideHomo sapiens (human)EC50500.000010
4-(3-hydroxyphenyl)-1-(2-oxolanylmethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)EC5019.760010
N'-(9-acridinyl)-2-(3-methylphenoxy)acetohydrazideHomo sapiens (human)EC50500.000010
4-[[3-[(4-chlorophenyl)sulfonylamino]-2-quinoxalinyl]amino]-1-piperidinecarboxylic acid ethyl esterHomo sapiens (human)EC5059.680010
N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamideHomo sapiens (human)EC50500.000010
1-[3-[(7-cyano-[1,3]dioxolo[4,5-g]quinolin-6-yl)amino]propyl]-3-(3-ethoxypropyl)thioureaHomo sapiens (human)EC5013.090010
LSM-18934Homo sapiens (human)EC50500.000010
2-amino-4-[5-methyl-2-(methylthio)-3-thiophenyl]-5-oxo-1-(3-pyridinyl)-4,6,7,8-tetrahydroquinoline-3-carbonitrileHomo sapiens (human)EC5058.550010
1-acetyl-N-propyl-3,4-dihydro-2H-quinoline-6-sulfonamideHomo sapiens (human)EC50500.000010
3-(5-chloro-2-methylphenyl)-6-(2,6-dimethyl-4-morpholinyl)-1H-pyrimidine-2,4-dioneHomo sapiens (human)EC50500.000010
4-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-3-oxobutanoic acid ethyl esterHomo sapiens (human)EC5024.170010
N-(6-acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-3,4,5-trimethoxybenzamideHomo sapiens (human)EC5074.650010
1-[3-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acidHomo sapiens (human)EC508.572010
3-(4-chlorophenyl)-6-(4-methyl-1-piperazinyl)-1H-pyrimidine-2,4-dioneHomo sapiens (human)EC50500.000010
2-[2-(7-methoxy-2-oxo-1H-quinolin-3-yl)ethyl]isoindole-1,3-dioneHomo sapiens (human)EC50500.000010
6-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-ethyl-1H-pyrimidine-2,4-dioneHomo sapiens (human)EC50500.000010
7-hydroxy-3-(4-methoxyphenyl)-4-methylcoumarinHomo sapiens (human)EC5022.020010
3,3'-diethylthiacarbocyanine iodideHomo sapiens (human)EC50119.500010
1-(3,4-dimethylphenyl)-2,5-dioxo-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarbonitrileHomo sapiens (human)EC501.779010
6-chloro-3-[2-[4-[2,3-dihydro-1,4-benzodioxin-3-yl(oxo)methyl]-1-piperazinyl]-2-oxoethyl]-7-hydroxy-4-methyl-1-benzopyran-2-oneHomo sapiens (human)EC502.898010
3-[4-(trifluoromethyl)phenyl]-N-[[2-(trifluoromethyl)phenyl]methyl]-4,5-dihydroisoxazole-5-carboxamideHomo sapiens (human)EC50500.000010
3-[[1-[1-(methylthio)propan-2-yl]-4-piperidinyl]oxy]-N-(2-pyridinylmethyl)benzamideHomo sapiens (human)EC5060.020010
pyridoxal 4-methoxybenzoyl hydrazoneHomo sapiens (human)EC501.522010