A sodium/hydrogen exchanger 1 that is encoded in the genome of rat. [PRO:DAN]
Na(+)/H(+) exchanger 1;
NHE-1;
Solute carrier family 9 member 1
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 5-dimethylamiloride | Rattus norvegicus (Norway rat) | IC50 | 0.0230 | 1 | 0 |
| 5-dimethylamiloride | Rattus norvegicus (Norway rat) | Ki | 0.0230 | 2 | 0 |
| 5-(n,n-hexamethylene)amiloride | Rattus norvegicus (Norway rat) | Ki | 0.0130 | 2 | 0 |
| ethylisopropylamiloride | Rattus norvegicus (Norway rat) | IC50 | 0.0100 | 1 | 0 |
| ethylisopropylamiloride | Rattus norvegicus (Norway rat) | Ki | 0.0100 | 2 | 0 |
| celecoxib | Rattus norvegicus (Norway rat) | IC50 | 33.1000 | 1 | 1 |
| fenbufen | Rattus norvegicus (Norway rat) | IC50 | 3.9000 | 1 | 1 |
| amiloride | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 0 |
| amiloride | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 2 | 0 |
| cariporide | Rattus norvegicus (Norway rat) | IC50 | 0.0589 | 4 | 4 |