| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| thioflavin t | [no description available] | medium | 2 | 0 | benzothiazolium ion | |
| salicylic acid | [no description available] | medium | 2 | 0 | monohydroxybenzoic acid | algal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite |
| methyl-3-methoxy-4-hydroxystyryl ketone | [no description available] | medium | 1 | 0 | hydroxycinnamic acid | |
| 3-hydroxybenzaldehyde | [no description available] | medium | 1 | 0 | hydroxybenzaldehyde | |
| indole | [no description available] | medium | 1 | 0 | indole;
polycyclic heteroarene | Escherichia coli metabolite |
| indol-3-yl pyruvic acid | [no description available] | medium | 1 | 0 | 2-oxo monocarboxylic acid;
indol-3-yl carboxylic acid | plant metabolite;
Saccharomyces cerevisiae metabolite |
| melatonin | [no description available] | medium | 2 | 0 | acetamides;
tryptamines | anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger |
| tryptamine | [no description available] | medium | 1 | 0 | aminoalkylindole;
aralkylamino compound;
indole alkaloid;
tryptamines | human metabolite;
mouse metabolite;
plant metabolite |
| benzophenone | [no description available] | medium | 1 | 0 | benzophenones | photosensitizing agent;
plant metabolite |
| fenofibrate | [no description available] | medium | 1 | 0 | aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes | antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic |
| indomethacin | [no description available] | medium | 1 | 0 | aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole | analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic |
| juglone | [no description available] | medium | 1 | 0 | hydroxy-1,4-naphthoquinone | geroprotector;
herbicide;
reactive oxygen species generator |
| masoprocol | [no description available] | medium | 1 | 0 | catechols;
lignan;
tetrol | antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite |
| perphenazine | [no description available] | medium | 1 | 0 | N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines | antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug |
| phenolsulfonphthalein | [no description available] | medium | 1 | 0 | 2,1-benzoxathiole;
arenesulfonate ester;
phenols;
sultone | acid-base indicator;
diagnostic agent;
two-colour indicator |
| p-dimethylaminoazobenzene | [no description available] | medium | 1 | 0 | azobenzenes | |
| methylene blue | [no description available] | medium | 1 | 0 | organic chloride salt | acid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer |
| tryptophan | [no description available] | medium | 1 | 0 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan | antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| anthrone | [no description available] | medium | 1 | 0 | anthracenone | radical scavenger |
| aminacrine | [no description available] | medium | 1 | 0 | aminoacridines;
primary amino compound | acid-base indicator;
antiinfective agent;
antiseptic drug;
fluorescent dye;
MALDI matrix material;
mutagen |
| acetophenone | [no description available] | medium | 1 | 0 | acetophenones | animal metabolite;
photosensitizing agent;
xenobiotic |
| chloranil | [no description available] | medium | 1 | 0 | 1,4-benzoquinones;
organochlorine compound | EC 2.7.1.33 (pantothenate kinase) inhibitor;
metabolite |
| veratraldehyde | [no description available] | medium | 1 | 0 | benzaldehydes;
dimethoxybenzene | antifungal agent |
| 2-vanillin | [no description available] | medium | 1 | 0 | benzaldehydes;
guaiacols | antimutagen;
plant metabolite |
| catechin | [no description available] | medium | 1 | 0 | catechin | antioxidant;
plant metabolite |
| flavanone | [no description available] | medium | 1 | 0 | flavanones | |
| indole-3-carbaldehyde | [no description available] | medium | 1 | 0 | heteroarenecarbaldehyde;
indole alkaloid;
indoles | bacterial metabolite;
human xenobiotic metabolite;
marine metabolite;
plant metabolite |
| methyl red | [no description available] | medium | 1 | 0 | | |
| 1,2-naphthoquinone | [no description available] | medium | 1 | 0 | 1,2-naphthoquinones | aryl hydrocarbon receptor agonist;
carcinogenic agent |
| congo red | [no description available] | medium | 7 | 0 | bis(azo) compound | |
| 4,4'-bisphenol f | [no description available] | medium | 1 | 0 | bisphenol;
diarylmethane | environmental food contaminant;
xenoestrogen |
| azure a | [no description available] | medium | 1 | 0 | | |
| pontamine sky blue | [no description available] | medium | 1 | 0 | | |
| 4-anisaldehyde | [no description available] | medium | 1 | 0 | benzaldehydes | bacterial metabolite;
human urinary metabolite;
insect repellent;
plant metabolite |
| epigallocatechin gallate | [no description available] | medium | 1 | 0 | flavans;
gallate ester;
polyphenol | antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite |
| neocuproine | [no description available] | medium | 1 | 0 | phenanthrolines | chelator;
copper chelator |
| 4,4'-Dihydroxybenzophenone | [no description available] | medium | 1 | 0 | benzophenones | |
| 2,2'-Dihydroxybenzophenone | [no description available] | medium | 1 | 0 | benzophenones | |
| 2,3,4-trihydroxbenzophenone | [no description available] | medium | 1 | 0 | benzenetriol;
hydroxybenzophenone | drug metabolite;
EC 1.14.18.1 (tyrosinase) inhibitor;
human urinary metabolite;
quorum sensing inhibitor;
rat metabolite |
| epicatechin | [no description available] | medium | 1 | 0 | catechin;
polyphenol | antioxidant |
| 5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate) | [no description available] | medium | 1 | 0 | | |
| naringenin | [no description available] | medium | 1 | 0 | (2S)-flavan-4-one;
naringenin | expectorant;
plant metabolite |
| taxifolin | [no description available] | medium | 1 | 0 | taxifolin | metabolite |
| resveratrol | [no description available] | medium | 1 | 0 | resveratrol | antioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger |
| ferulic acid | [no description available] | medium | 1 | 0 | ferulic acids | anti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite |
| 3-coumaric acid | [no description available] | medium | 1 | 0 | 3-coumaric acid | |
| chalcone | [no description available] | medium | 1 | 0 | chalcone | EC 3.2.1.1 (alpha-amylase) inhibitor |
| quercetin | [no description available] | medium | 1 | 0 | 7-hydroxyflavonol;
pentahydroxyflavone | antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger |
| apigenin | [no description available] | medium | 1 | 0 | trihydroxyflavone | antineoplastic agent;
metabolite |
| kaempferol | [no description available] | medium | 1 | 0 | 7-hydroxyflavonol;
flavonols;
tetrahydroxyflavone | antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite |
| genistein | [no description available] | medium | 1 | 0 | 7-hydroxyisoflavones | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor |
| myricetin | [no description available] | medium | 1 | 0 | 7-hydroxyflavonol;
hexahydroxyflavone | antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite |
| rosmarinic acid | [no description available] | medium | 1 | 0 | rosmarinic acid | geroprotector;
plant metabolite |
| ellagic acid | [no description available] | medium | 1 | 0 | catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol | antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent |
| diferuloylputrescine | [no description available] | medium | 1 | 0 | hydroxycinnamic acid | |
| 3,4',5-trimethoxystilbene | [no description available] | medium | 1 | 0 | | |
| phenyl-3-methoxy-4-hydroxystyryl ketone | [no description available] | medium | 1 | 0 | | |
| dimethoxycurcumin | [no description available] | medium | 1 | 0 | | |
| tetracycline | [no description available] | medium | 1 | 0 | | |
| minocycline | [no description available] | medium | 1 | 0 | | |
| meclan | [no description available] | medium | 1 | 0 | | |
| rolitetracycline | [no description available] | medium | 1 | 0 | | |
| azure c | [no description available] | medium | 1 | 0 | | |
| thioflavin t | [no description available] | medium | 3 | 0 | organic chloride salt | fluorochrome;
geroprotector;
histological dye |
| 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole | [no description available] | medium | 2 | 0 | | |
| 2-(4-(dimethylamino)styryl)benzothiazole | [no description available] | medium | 1 | 0 | | |
| 2-(4'-methylaminophenyl)benzothiazole | [no description available] | medium | 1 | 0 | | |
| 4-(6-iodo-2-imidazo[1,2-a]pyridinyl)-N,N-dimethylaniline | [no description available] | medium | 1 | 0 | imidazoles | |
| 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole | [no description available] | medium | 1 | 0 | | |
| florbetapir f 18 | [no description available] | medium | 2 | 0 | (18)F radiopharmaceutical;
aromatic ether;
organofluorine compound;
pyridines;
substituted aniline | radioactive imaging agent |
| bay94 9172 | [no description available] | medium | 1 | 0 | (18)F radiopharmaceutical;
aromatic ether;
polyether;
secondary amino compound;
stilbenoid;
substituted aniline | radioactive imaging agent |
| vizamyl | [no description available] | medium | 1 | 0 | (18)F radiopharmaceutical;
aromatic amine;
benzothiazoles;
secondary amino compound | radioactive imaging agent |
| tanespimycin | [no description available] | medium | 1 | 0 | 1,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound;
secondary amino compound | antineoplastic agent;
apoptosis inducer;
Hsp90 inhibitor |
| ibuprofen | [no description available] | medium | 2 | 0 | monocarboxylic acid | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic |
| trehalose | [no description available] | medium | 1 | 0 | trehalose | Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| curcumin | [no description available] | medium | 2 | 0 | aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol | anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger |
| amyloid beta-peptides | [no description available] | medium | 1 | 0 | | |
| naproxen | [no description available] | medium | 1 | 0 | methoxynaphthalene;
monocarboxylic acid | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic |
| thiazoles | [no description available] | medium | 2 | 0 | 1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
| n,n'-bis(3-hydroxyphenyl)pyridazine-3,6-diamine | [no description available] | medium | 1 | 0 | | |
| technetium | [no description available] | medium | 1 | 0 | manganese group element atom | |
| rifampin | [no description available] | medium | 1 | 0 | cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion | angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor |
| gossypol | [no description available] | medium | 1 | 0 | | |
| creatine | [no description available] | medium | 1 | 0 | glycine derivative;
guanidines;
zwitterion | geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical |