A protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha that is encoded in the genome of rat. [OMA:Q04631, PRO:DNx]
EC 2.5.1.58;
EC 2.5.1.59;
CAAX farnesyltransferase subunit alpha;
FTase-alpha;
Ras proteins prenyltransferase subunit alpha;
Type I protein geranyl-geranyltransferase subunit alpha;
GGTase-I-alpha
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| r115777 | Rattus norvegicus (Norway rat) | IC50 | 0.0170 | 1 | 1 |
| lonafarnib | Rattus norvegicus (Norway rat) | IC50 | 0.4173 | 3 | 3 |
| l 778,123 | Rattus norvegicus (Norway rat) | IC50 | 0.0036 | 1 | 1 |
| squalestatin 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 1 | 1 |
| sch 44342 | Rattus norvegicus (Norway rat) | IC50 | 0.2500 | 1 | 1 |
| antroquinonol d | Rattus norvegicus (Norway rat) | IC50 | 2.9860 | 1 | 1 |