Proteins > Sodium/glucose cotransporter 2
Page last updated: 2024-08-07 23:36:19
Sodium/glucose cotransporter 2
A sodium/glucose cotransporter 2 that is encoded in the genome of rat. [OMA:P53792, PRO:DNx]
Synonyms
Na(+)/glucose cotransporter 2;
Low affinity sodium-glucose cotransporter;
Solute carrier family 5 member 2
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| phlorhizin | Rattus norvegicus (Norway rat) | IC50 | 0.0960 | 1 | 1 |
| pf 04971729 | Rattus norvegicus (Norway rat) | IC50 | 0.0012 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| dapagliflozin | Rattus norvegicus (Norway rat) | EC50 | 0.0030 | 2 | 2 |
Development of the renal glucose reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2.Journal of medicinal chemistry, , Apr-09, Volume: 52, Issue:7, 2009
Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.Journal of medicinal chemistry, , Mar-13, Volume: 51, Issue:5, 2008