lamotrigine has been researched along with Sensitivity and Specificity in 44 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " the LTA by using trypan blue exclusion and to determine the utility of the assay to confirm drug hypersensitivity syndrome (DHS) to sulphonamides (SMX) and aromatic anticonvulsants." | 3.70 | A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. ( Malkiewicz, IM; Neuman, MG; Shear, NH, 2000) |
| "Lamotrigine tablets were bioequivalent." | 2.74 | Development of an ultra-performance liquid chromatography-tandem mass spectrometry micromethod for quantification of lamotrigine in human plasma and its use in a bioequivalence trial. ( Marcelín-Jiménez, G; Martínez, MM; Mendoza-Morales, L; P Angeles Moreno, AC; Rivera-Espinosa, L, 2009) |
| "Lamotrigine (LTG) is a widely used anti-epileptic drug that is administered to avoid seizures and to maintain seizure-free status." | 1.51 | Determination of lamotrigine in human plasma using liquid chromatography-tandem mass spectrometry. ( Bito, R; Doi, M; Fukumoto, M; Itabashi, S; Kitaichi, K; Nishina, M; Soda, M; Usui, S, 2019) |
| "Lamotrigine was extracted from plasma through a simple protein precipitation and analyzed by fast liquid chromatography coupled to heated electrospray ionization with tandem mass spectrometric detection." | 1.42 | Quantification of lamotrigine in patient plasma using a fast liquid chromatography-tandem mass spectrometry method with backflush technology. ( Jiang, W; Jones, JW; Kane, MA; Polli, JE; Wong, JM, 2015) |
| "Lamotrigine was used as internal standards (IS) to ensure the precision and accuracy of the method." | 1.39 | A simple and sensitive HPLC-UV determination of 7-O-succinyl macrolactin A in rat plasma and urine and its application to a pharmacokinetic study. ( Jung, JW; Kang, HE; Kang, JS; Kim, CG; Kim, DH; Kim, JM, 2013) |
| "Lamotrigine was eluted at 1." | 1.36 | Determination of lamotrigine in human serum by high-performance liquid chromatography–tandem mass spectrometry. ( Heo, K; Kim, HS; Kim, JH; Kwon, OH; Lee, BI; Lee, W, 2010) |
| " The proposed methods were successfully applied for the determination of lamotrigine in bulk powder, in dosage form and in presence of its impurity." | 1.34 | Development and validation of spectrophotometric, TLC and HPLC methods for the determination of lamotrigine in presence of its impurity. ( Taha, EA; Youssef, NF, 2007) |
| "Lamotrigine extraction was performed on a reversed-phase Oasis HBL preparation column." | 1.31 | Optimized procedure for lamotrigine analysis in serum by high-performance liquid chromatography without interferences from other frequently coadministered anticonvulsants. ( Arroyo, S; Corbella, J; Rodamilans, M; Torra, M, 2000) |
| "Lamotrigine (lamictal) is a new anticonvulsant drug recently approved by the FDA for clinical use." | 1.30 | Lamotrigine analysis in plasma by gas chromatography-mass spectrometry after conversion to a tert.-butyldimethylsilyl derivative. ( Dasgupta, A; Hart, AP, 1997) |
| "Lamotrigine was eluted at 0." | 1.30 | Determination of lamotrigine in human serum by liquid chromatography. ( Pascual, C; Pou, L; Vidal, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 18 (40.91) | 29.6817 |
| 2010's | 18 (40.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Linder, C | 1 |
| Hansson, A | 1 |
| Sadek, S | 1 |
| Gustafsson, LL | 1 |
| Pohanka, A | 1 |
| Wen, D | 1 |
| Chen, Z | 2 |
| Yang, C | 1 |
| Liu, H | 1 |
| Li, H | 2 |
| Chen, J | 1 |
| Dai, Q | 1 |
| Zhong, G | 1 |
| Qin, J | 1 |
| Ni, G | 1 |
| Huang, M | 1 |
| Zhou, L | 1 |
| Wang, X | 2 |
| Namdev, KK | 1 |
| Dwivedi, J | 1 |
| Chilkoti, DC | 1 |
| Sharma, S | 1 |
| Itabashi, S | 1 |
| Bito, R | 1 |
| Nishina, M | 1 |
| Fukumoto, M | 1 |
| Soda, M | 1 |
| Doi, M | 1 |
| Usui, S | 1 |
| Kitaichi, K | 1 |
| Wong, JM | 1 |
| Jones, JW | 1 |
| Jiang, W | 1 |
| Polli, JE | 1 |
| Kane, MA | 1 |
| Deeb, S | 1 |
| McKeown, DA | 1 |
| Torrance, HJ | 1 |
| Wylie, FM | 1 |
| Logan, BK | 1 |
| Scott, KS | 1 |
| Dolk, H | 1 |
| Wang, H | 1 |
| Loane, M | 1 |
| Morris, J | 1 |
| Garne, E | 1 |
| Addor, MC | 1 |
| Arriola, L | 1 |
| Bakker, M | 1 |
| Barisic, I | 1 |
| Doray, B | 1 |
| Gatt, M | 1 |
| Kallen, K | 1 |
| Khoshnood, B | 1 |
| Klungsoyr, K | 1 |
| Lahesmaa-Korpinen, AM | 1 |
| Latos-Bielenska, A | 1 |
| Mejnartowicz, JP | 1 |
| Nelen, V | 1 |
| Neville, A | 1 |
| O'Mahony, M | 1 |
| Pierini, A | 1 |
| Rißmann, A | 1 |
| Tucker, D | 1 |
| Wellesley, D | 1 |
| Wiesel, A | 1 |
| de Jong-van den Berg, LT | 1 |
| Aebischer, B | 1 |
| Elsig, S | 1 |
| Taeymans, J | 1 |
| Pomp, S | 1 |
| Kuhness, D | 1 |
| Barcaro, G | 1 |
| Sementa, L | 1 |
| Mankad, V | 1 |
| Fortunelli, A | 1 |
| Sterrer, M | 1 |
| Netzer, FP | 1 |
| Surnev, S | 1 |
| Schmieder, AH | 1 |
| Caruthers, SD | 1 |
| Keupp, J | 1 |
| Wickline, SA | 1 |
| Lanza, GM | 1 |
| Lowe, J | 1 |
| Wodarcyk, AJ | 1 |
| Floyd, KT | 1 |
| Rastogi, N | 1 |
| Schultz, EJ | 1 |
| Swager, SA | 1 |
| Chadwick, JA | 1 |
| Tran, T | 1 |
| Raman, SV | 1 |
| Janssen, PM | 1 |
| Rafael-Fortney, JA | 1 |
| Alcalay, RN | 1 |
| Levy, OA | 1 |
| Wolf, P | 1 |
| Oliva, P | 1 |
| Zhang, XK | 1 |
| Waters, CH | 1 |
| Fahn, S | 1 |
| Kang, U | 1 |
| Liong, C | 1 |
| Ford, B | 1 |
| Mazzoni, P | 1 |
| Kuo, S | 1 |
| Johnson, A | 1 |
| Xiong, L | 1 |
| Rouleau, GA | 1 |
| Chung, W | 1 |
| Marder, KS | 1 |
| Gan-Or, Z | 1 |
| Kamei, K | 1 |
| Terao, T | 1 |
| Katayama, Y | 1 |
| Hatano, K | 1 |
| Kodama, K | 1 |
| Shirahama, M | 1 |
| Sakai, A | 1 |
| Hirakawa, H | 1 |
| Mizokami, Y | 1 |
| Shiotsuki, I | 1 |
| Ishii, N | 1 |
| Inoue, Y | 1 |
| Akboga, MK | 1 |
| Yayla, C | 1 |
| Balci, KG | 1 |
| Ozeke, O | 1 |
| Maden, O | 1 |
| Kisacik, H | 1 |
| Temizhan, A | 1 |
| Aydogdu, S | 1 |
| Zhu, J | 2 |
| Ying, SH | 1 |
| Feng, MG | 1 |
| Zhang, XG | 1 |
| Wang, L | 1 |
| Hao, YY | 1 |
| Liang, GD | 1 |
| Ma, YH | 1 |
| Yang, GS | 1 |
| Hu, JH | 1 |
| Pfeifer, L | 1 |
| Goertz, RS | 1 |
| Neurath, MF | 1 |
| Strobel, D | 1 |
| Wildner, D | 1 |
| Lin, JT | 1 |
| Yang, XN | 1 |
| Zhong, WZ | 1 |
| Liao, RQ | 1 |
| Dong, S | 1 |
| Nie, Q | 1 |
| Weng, SX | 1 |
| Fang, XJ | 1 |
| Zheng, JY | 1 |
| Wu, YL | 1 |
| Řezanka, T | 1 |
| Kaineder, K | 1 |
| Mezricky, D | 1 |
| Řezanka, M | 1 |
| Bišová, K | 1 |
| Zachleder, V | 1 |
| Vítová, M | 1 |
| Rinker, JA | 1 |
| Marshall, SA | 1 |
| Mazzone, CM | 1 |
| Lowery-Gionta, EG | 1 |
| Gulati, V | 1 |
| Pleil, KE | 1 |
| Kash, TL | 1 |
| Navarro, M | 1 |
| Thiele, TE | 1 |
| Zhang, Y | 1 |
| Huang, Y | 1 |
| Jin, Z | 1 |
| Li, X | 1 |
| Li, B | 1 |
| Xu, P | 1 |
| Huang, P | 1 |
| Liu, C | 1 |
| Fokdal, L | 1 |
| Sturdza, A | 1 |
| Mazeron, R | 1 |
| Haie-Meder, C | 1 |
| Tan, LT | 1 |
| Gillham, C | 1 |
| Šegedin, B | 1 |
| Jürgenliemk-Schultz, I | 1 |
| Kirisits, C | 1 |
| Hoskin, P | 1 |
| Pötter, R | 1 |
| Lindegaard, JC | 1 |
| Tanderup, K | 1 |
| Levin, DE | 1 |
| Schmitz, AJ | 1 |
| Hines, SM | 1 |
| Hines, KJ | 1 |
| Tucker, MJ | 1 |
| Brewer, SH | 1 |
| Fenlon, EE | 1 |
| Álvarez-Pérez, S | 1 |
| Blanco, JL | 1 |
| Peláez, T | 1 |
| Martínez-Nevado, E | 1 |
| García, ME | 1 |
| Puckerin, AA | 1 |
| Chang, DD | 1 |
| Subramanyam, P | 1 |
| Colecraft, HM | 1 |
| Dogan, H | 1 |
| Coteli, E | 1 |
| Karatas, F | 1 |
| Ceylan, O | 1 |
| Sahin, MD | 1 |
| Akdamar, G | 1 |
| Kryczyk, A | 1 |
| Żmudzki, P | 1 |
| Hubicka, U | 1 |
| Giovannelli, D | 1 |
| Chung, M | 1 |
| Staley, J | 1 |
| Starovoytov, V | 1 |
| Le Bris, N | 1 |
| Vetriani, C | 1 |
| Chen, W | 1 |
| Wu, L | 1 |
| Liu, X | 1 |
| Shen, Y | 1 |
| Liang, Y | 1 |
| Tan, H | 1 |
| Yang, Y | 1 |
| Liu, Q | 1 |
| Wang, M | 1 |
| Liu, L | 1 |
| Liu, B | 1 |
| Liu, GH | 1 |
| Zhu, YJ | 1 |
| Wang, JP | 1 |
| Che, JM | 1 |
| Chen, QQ | 1 |
| Maucksch, U | 1 |
| Runge, R | 1 |
| Wunderlich, G | 1 |
| Freudenberg, R | 1 |
| Naumann, A | 1 |
| Kotzerke, J | 1 |
| Burger, DM | 1 |
| Huisman, A | 1 |
| Van Ewijk, N | 1 |
| Neisingh, H | 1 |
| Van Uden, P | 1 |
| Rongen, GA | 1 |
| Koopmans, P | 1 |
| Bertz, RJ | 1 |
| Zufía, L | 1 |
| Aldaz, A | 1 |
| Ibáñez, N | 1 |
| Viteri, C | 1 |
| Verdian, L | 1 |
| Yi, Y | 1 |
| El-Enany, NM | 1 |
| El-Sherbiny, DT | 1 |
| Abdelal, AA | 1 |
| Belal, FF | 1 |
| Lee, W | 1 |
| Kim, JH | 1 |
| Kim, HS | 1 |
| Kwon, OH | 1 |
| Lee, BI | 1 |
| Heo, K | 1 |
| Morgan, PE | 1 |
| Fisher, DS | 1 |
| Evers, R | 1 |
| Flanagan, RJ | 1 |
| Kemp, DE | 1 |
| Ganocy, SJ | 1 |
| Brecher, M | 1 |
| Carlson, BX | 1 |
| Edwards, S | 1 |
| Eudicone, JM | 1 |
| Evoniuk, G | 1 |
| Jansen, W | 1 |
| Leon, AC | 1 |
| Minkwitz, M | 1 |
| Pikalov, A | 1 |
| Stassen, HH | 1 |
| Szegedi, A | 1 |
| Tohen, M | 1 |
| Van Willigenburg, AP | 1 |
| Calabrese, JR | 1 |
| Marcelín-Jiménez, G | 1 |
| P Angeles Moreno, AC | 1 |
| Mendoza-Morales, L | 1 |
| Rivera-Espinosa, L | 1 |
| Martínez, MM | 1 |
| Madhavaram, H | 1 |
| Woollard, GA | 1 |
| Couch, RA | 1 |
| Antonilli, L | 1 |
| Brusadin, V | 1 |
| Filipponi, F | 1 |
| Guglielmi, R | 1 |
| Nencini, P | 1 |
| Tai, SS | 1 |
| Yeh, CY | 1 |
| Phinney, KW | 1 |
| Hotha, KK | 1 |
| Kumar, SS | 1 |
| Bharathi, DV | 1 |
| Venkateswarulu, V | 1 |
| Kim, JM | 1 |
| Jung, JW | 1 |
| Kim, DH | 1 |
| Kang, JS | 1 |
| Kim, CG | 1 |
| Kang, HE | 1 |
| Pucci, V | 1 |
| Bugamelli, F | 1 |
| Baccini, C | 1 |
| Raggi, MA | 1 |
| Franceschi, L | 1 |
| Furlanut, M | 1 |
| Patil, KM | 1 |
| Bodhankar, SL | 1 |
| Cantú, MD | 1 |
| Toso, DR | 1 |
| Lacerda, CA | 1 |
| Lanças, FM | 1 |
| Carrilho, E | 1 |
| Queiroz, ME | 1 |
| Greiner-Sosanko, E | 1 |
| Lower, DR | 1 |
| Virji, MA | 1 |
| Krasowski, MD | 1 |
| Youssef, NF | 1 |
| Taha, EA | 1 |
| Greiner, C | 1 |
| Haen, E | 1 |
| Vermeij, TA | 1 |
| Edelbroek, PM | 1 |
| Carrier, DJ | 1 |
| Eckers, C | 1 |
| Wolff, JC | 1 |
| Bartoli, A | 1 |
| Marchiselli, R | 1 |
| Gatti, G | 1 |
| Londero, D | 1 |
| Lo Greco, P | 1 |
| Dasgupta, A | 1 |
| Hart, AP | 1 |
| Matar, KM | 1 |
| Nicholls, PJ | 1 |
| Bawazir, SA | 1 |
| al-Hassan, MI | 1 |
| Tekle, A | 1 |
| Angelis-Stoforidis, P | 1 |
| Morgan, DJ | 1 |
| O'Brien, TJ | 1 |
| Vajda, FJ | 1 |
| Vidal, E | 1 |
| Pascual, C | 1 |
| Pou, L | 1 |
| Barbosa, NR | 1 |
| Mídio, AF | 1 |
| Torra, M | 1 |
| Rodamilans, M | 1 |
| Arroyo, S | 1 |
| Corbella, J | 1 |
| Neuman, MG | 1 |
| Malkiewicz, IM | 1 |
| Shear, NH | 1 |
| Castel-Branco, MM | 2 |
| Almeida, AM | 2 |
| Falcão, AC | 2 |
| Macedo, TA | 1 |
| Caramona, MM | 1 |
| Lopez, FG | 1 |
| Fazio, A | 1 |
| Artesi, C | 1 |
| Russo, M | 1 |
| Trio, R | 1 |
| Oteri, G | 1 |
| Pisani, F | 1 |
| Sailstad, JM | 1 |
| Findlay, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Generic Substitution of Antiepileptic Drugs[NCT02429596] | Phase 4 | 200 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lamotrigine and Sensitivity and Specificity
2 trials available for lamotrigine and Sensitivity and Specificity
| Article | Year |
|---|---|
Clinical value of early partial symptomatic improvement in the prediction of response and remission during short-term treatment trials in 3369 subjects with bipolar I or II depression.
Topics: Antidepressive Agents, Second-Generation; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benz | 2011 |
Development of an ultra-performance liquid chromatography-tandem mass spectrometry micromethod for quantification of lamotrigine in human plasma and its use in a bioequivalence trial.
Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Chromatography, Liquid; Femal | 2009 |
41 other studies available for lamotrigine and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Carbamazepine, lamotrigine, levetiracetam and valproic acid in dried blood spots with liquid chromatography tandem mass spectrometry; method development and validation.
Topics: Carbamazepine; Chromatography, Liquid; Dried Blood Spot Testing; Female; Humans; Lamotrigine; Leveti | 2018 |
A rapid and simple HPLC-MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Chromatography, High Pressure Liquid; Drug Interac | 2018 |
A simple, rapid and stability indicating validated method for quantification of lamotrigine in human plasma and dry plasma spot using LC-ESI-MS/MS: Application in clinical study.
Topics: Chromatography, Liquid; Dried Blood Spot Testing; Drug Stability; Humans; Lamotrigine; Linear Models | 2018 |
Determination of lamotrigine in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Anticonvulsants; Blood Chemical Analysis; Calibration; Chromatography, Liquid; Humans; Lamotrigine; | 2019 |
Quantification of lamotrigine in patient plasma using a fast liquid chromatography-tandem mass spectrometry method with backflush technology.
Topics: Anticonvulsants; Chromatography, Liquid; Humans; Lamotrigine; Limit of Detection; Reproducibility of | 2015 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Mo | 2014 |
Lamotrigine use in pregnancy and risk of orofacial cleft and other congenital anomalies.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Case-Control Studies; Cleft Lip; Cleft Palate; | 2016 |
The effect of atazanavir and atazanavir/ritonavir on UDP-glucuronosyltransferase using lamotrigine as a phenotypic probe.
Topics: Administration, Oral; Adult; Anti-HIV Agents; Atazanavir Sulfate; Confidence Intervals; Dose-Respons | 2008 |
LC method for the therapeutic drug monitoring of lamotrigine: evaluation of the assay performance and validation of its application in the routine area.
Topics: Anticonvulsants; Biological Assay; Chromatography, Liquid; Drug Monitoring; Humans; Lamotrigine; Log | 2009 |
Cost-utility analysis of rufinamide versus topiramate and lamotrigine for the treatment of children with Lennox-Gastaut Syndrome in the United Kingdom.
Topics: Anticonvulsants; Child; Confidence Intervals; Cost-Benefit Analysis; Drug Utilization; Epilepsy; Fol | 2010 |
Validated spectrofluorimetric method for the determination of lamotrigine in tablets and human plasma through derivatization with o-phthalaldehyde.
Topics: Blood Chemical Analysis; Child; Epilepsy; Fluorescence; Humans; Hydrogen-Ion Concentration; Lamotrig | 2010 |
Determination of lamotrigine in human serum by high-performance liquid chromatography–tandem mass spectrometry.
Topics: Anticonvulsants; Antimanic Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; | 2010 |
A rapid and simple assay for lamotrigine in serum/plasma by HPLC, and comparison with an immunoassay.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Immunoassay; Lamotrigine | 2011 |
Measurement of serum lamotrigine by high performance liquid chromatography using a phenyltriazine as internal standard.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Reference Standards; Sen | 2012 |
Development and validation of an analytical method based on high performance thin layer chromatography for the simultaneous determination of lamotrigine, zonisamide and levetiracetam in human plasma.
Topics: Anticonvulsants; Calibration; Chromatography, Thin Layer; Drug Monitoring; Humans; Isoxazoles; Lamot | 2011 |
Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, Reverse-Phase; Fructose; Humans; Indicator Dilution Techniques; Lam | 2011 |
Rapid and sensitive LC-MS/MS method for quantification of lamotrigine in human plasma: application to a human pharmacokinetic study.
Topics: Anticonvulsants; Chromatography, Liquid; Humans; Lamotrigine; Liquid-Liquid Extraction; Male; Sensit | 2012 |
A simple and sensitive HPLC-UV determination of 7-O-succinyl macrolactin A in rat plasma and urine and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Lamotrigine; Linear Models; Macrolide | 2013 |
Analysis of lamotrigine and its metabolites in human plasma and urine by micellar electrokinetic capillary chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Epilepsy; H | 2005 |
A simple method to monitor plasma concentrations of oxcarbazepine, carbamazepine, their main metabolites and lamotrigine in epileptic patients.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Hum | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; | 2005 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liq | 2006 |
Simultaneous determination of lamotrigine, zonisamide, and carbamazepine in human plasma by high-performance liquid chromatography.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Lam | 2007 |
Development and validation of spectrophotometric, TLC and HPLC methods for the determination of lamotrigine in presence of its impurity.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Lamotrigine; Repr | 2007 |
Development of a simple column-switching high-performance liquid chromatography (HPLC) method for rapid and simultaneous routine serum monitoring of lamotrigine, oxcarbazepine and 10-monohydroxycarbazepine (MHD).
Topics: Animals; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Lamotrigine; | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure | 2007 |
"In-source" fragmentation of an isobaric impurity of lamotrigine for its measurement by liquid chromatography tandem mass spectrometry after pre-concentration using solid phase extraction.
Topics: Acetonitriles; Anticonvulsants; Chromatography, Liquid; Drug Contamination; Lamotrigine; Molecular S | 2008 |
A rapid and specific assay for the determination of lamotrigine in human plasma by normal-phase HPLC.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Reproducibility of Resul | 1997 |
New micromethod for the determination of lamotrigine in human plasma by high-performance liquid chromatography.
Topics: Adult; Anticonvulsants; Child; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Microchemi | 1997 |
Lamotrigine analysis in plasma by gas chromatography-mass spectrometry after conversion to a tert.-butyldimethylsilyl derivative.
Topics: Anticonvulsants; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Lamotrigine; | 1997 |
A rapid liquid chromatographic method for the determination of lamotrigine in plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Drug Stability; Evaluation Studies as Topic; Hu | 1998 |
Determination of lamotrigine in human plasma by high-performance liquid chromatography.
Topics: Adult; Anticonvulsants; Chromatography, High Pressure Liquid; Female; Humans; Lamotrigine; Male; Mid | 1999 |
Determination of lamotrigine in human serum by liquid chromatography.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Indicator | 1999 |
Validated high-performance liquid chromatographic method for the determination of lamotrigine in human plasma.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Reference Standards; Rep | 2000 |
Optimized procedure for lamotrigine analysis in serum by high-performance liquid chromatography without interferences from other frequently coadministered anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Chromatography, High Pressure Liquid; Drug Administration Schedu | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Surviva | 2000 |
Lamotrigine analysis in blood and brain by high-performance liquid chromatography.
Topics: Animals; Anticonvulsants; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Stability; Epi | 2001 |
Linear regression for calibration lines revisited: weighting schemes for bioanalytical methods.
Topics: Calibration; Chromatography, High Pressure Liquid; Lamotrigine; Regression Analysis; Sensitivity and | 2002 |
A liquid chromatographic assay using a high-speed column for the determination of lamotrigine, a new antiepileptic drug, in human plasma.
Topics: Anticonvulsants; Chromatography, Liquid; Humans; Lamotrigine; Sensitivity and Specificity; Time Fact | 1992 |
Immunofluorometric assay for lamotrigine (Lamictal) in human plasma.
Topics: Animals; Antibody Specificity; Anticonvulsants; Binding, Competitive; Chromatography, High Pressure | 1991 |