Page last updated: 2024-12-07

penicilloate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

penicilloic acid: metabolites of penicillins obtained by alkaline cleavage; RN given refers to cpd with unknown MF; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

penicilloic acid : A thiazolidinedicarboxylic acid obtained via hydrolysis of the beta-lactam ring of a penicillin. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID52921568
MeSH IDM0052944

Synonyms (13)

Synonym
penicilloic acid
Q18387473
2-thiazolidineacetic acid, 4-carboxy-.alpha.-(formylamino)-5,5-dimethyl-, (2r-(2.alpha.(r*),4.beta.))-
2-thiazolidineacetic acid, 4-carboxy-.alpha.-(formylamino)-5,5-dimethyl-, (.alpha.r,2r,4s)-
unii-3a8ult6haq
142/3t
(2r,4s)-2-((r)-carboxy(formamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid
3a8ult6haq ,
bb-517
64527-07-7
2-thiazolidineacetic acid, 4-carboxy-alpha-(formylamino)-5,5-dimethyl-, (2r-(2alpha(r*),4beta))-
2-thiazolidineacetic acid, 4-carboxy-alpha-(formylamino)-5,5-dimethyl-, (alphar,2r,4s)-
pab-142

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" The method has proved to be reliable and was used in bioavailability studies for the development of a new oral penicillin-V formulation."( Determination of penicillin-V in human plasma by high-performance liquid chromatography and solid-phase extraction.
Krauwinkel, WJ; Volkers-Kamermans, NJ, 1996
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (56)

TimeframeStudies, This Drug (%)All Drugs %
pre-199026 (46.43)18.7374
1990's4 (7.14)18.2507
2000's2 (3.57)29.6817
2010's21 (37.50)24.3611
2020's3 (5.36)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (1.75%)4.05%
Observational0 (0.00%)0.25%
Other56 (98.25%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]