Page last updated: 2024-08-07 16:28:31
Metabotropic glutamate receptor 3
A metabotropic glutamate receptor 3 that is encoded in the genome of rat. [OMA:P31422, PRO:DNx]
Synonyms
mGluR3
Research
Bioassay Publications (15)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (20)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| alpha-methyl-4-carboxyphenylglycine | Rattus norvegicus (Norway rat) | IC50 | 270.0000 | 1 | 1 |
| nicotinamide mononucleotide | Rattus norvegicus (Norway rat) | Ki | 10,000.0000 | 1 | 2 |
| harmalan | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| eglumetad | Rattus norvegicus (Norway rat) | Ki | 0.2648 | 2 | 2 |
| 1-methyl-6-methoxy-dihydro-beta-carboline | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| tiazofurin | Rattus norvegicus (Norway rat) | Ki | 10,000.0000 | 1 | 2 |
| harmine | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| ly 341495 | Rattus norvegicus (Norway rat) | IC50 | 0.0168 | 4 | 4 |
| ly 341495 | Rattus norvegicus (Norway rat) | Ki | 0.0030 | 1 | 1 |
| mgs 0028 | Rattus norvegicus (Norway rat) | Ki | 0.0036 | 1 | 1 |
| vu0092273 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| ml289 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| d-glutamate | Rattus norvegicus (Norway rat) | EC50 | 9.0000 | 1 | 1 |
| glutamic acid | Rattus norvegicus (Norway rat) | EC50 | 1.6294 | 3 | 4 |
| quisqualic acid | Rattus norvegicus (Norway rat) | EC50 | 40.0000 | 1 | 1 |
| 1-amino-1,3-dicarboxycyclopentane | Rattus norvegicus (Norway rat) | EC50 | 8.0000 | 1 | 1 |
| 2-amino-4-phosphonobutyric acid | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| eglumetad | Rattus norvegicus (Norway rat) | EC50 | 0.0363 | 2 | 2 |
| l-2-(carboxypropyl)glycine | Rattus norvegicus (Norway rat) | EC50 | 0.6000 | 1 | 1 |
| 2-(2,3-dicarboxycyclopropyl)glycine | Rattus norvegicus (Norway rat) | EC50 | 0.1933 | 3 | 3 |
| 2r,4r-4-aminopyrrolidine-2,4-dicarboxylate | Rattus norvegicus (Norway rat) | EC50 | 1.7000 | 1 | 1 |
| ly 341495 | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| mgs 0028 | Rattus norvegicus (Norway rat) | EC50 | 50.0010 | 2 | 2 |
| 3,4-dicarboxyphenylglycine | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |