Proteins > Metabotropic glutamate receptor 3
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Metabotropic glutamate receptor 3
A metabotropic glutamate receptor 3 that is encoded in the genome of rat. [OMA:P31422, PRO:DNx]
Synonyms
mGluR3
Research
Bioassay Publications (15)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (20)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.Journal of medicinal chemistry, , Feb-11, Volume: 59, Issue:3, 2016
Metabotropic glutamate receptors: novel targets for drug development.Journal of medicinal chemistry, , Apr-28, Volume: 38, Issue:9, 1995
Synthesis and Pharmacological Characterization of C4Journal of medicinal chemistry, , 03-22, Volume: 61, Issue:6, 2018
Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists.Journal of medicinal chemistry, , Dec-14, Volume: 43, Issue:25, 2000
New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.Journal of medicinal chemistry, , Feb-11, Volume: 59, Issue:3, 2016
(2S,1'S,2'R,3'R)-2-(2'-Carboxy-3'-hydroxymethylcyclopropyl) glycine is a highly potent group 2 and 3 metabotropic glutamate receptor agonist with oral activity.Journal of medicinal chemistry, , Jan-15, Volume: 47, Issue:2, 2004
Metabotropic glutamate receptors: novel targets for drug development.Journal of medicinal chemistry, , Apr-28, Volume: 38, Issue:9, 1995
Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo.Bioorganic & medicinal chemistry letters, , Mar-01, Volume: 22, Issue:5, 2012
Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists.Journal of medicinal chemistry, , Aug-26, Volume: 47, Issue:18, 2004
Design, synthesis and preliminary evaluation of novel 3'-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors.Bioorganic & medicinal chemistry letters, , Dec-17, Volume: 11, Issue:24, 2001
2,3'-disubstituted-2-(2'-carboxycyclopropyl)glycines as potent and selective antagonists of metabotropic glutamate receptors.Bioorganic & medicinal chemistry letters, , Oct-20, Volume: 8, Issue:20, 1998
Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists.Journal of medicinal chemistry, , Dec-14, Volume: 43, Issue:25, 2000