Page last updated: 2024-08-07 23:59:24
Transient receptor potential cation channel subfamily A member 1
A transient receptor potential cation channel TRPA1 that is encoded in the genome of rat. [OMA:Q6RI86, PRO:DNx]
Synonyms
Ankyrin-like with transmembrane domains protein 1;
Wasabi receptor
Research
Bioassay Publications (19)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 14 (73.68) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
Compounds (34)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| allyl isothiocyanate | Rattus norvegicus (Norway rat) | IC50 | 85.9000 | 1 | 1 |
| thymol | Rattus norvegicus (Norway rat) | IC50 | 125.4000 | 1 | 1 |
| citronellol | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| citronellyl acetate | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| 2-aminoperimidine | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| resveratrol | Rattus norvegicus (Norway rat) | IC50 | 6.1975 | 4 | 4 |
| geraniol | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| benzylidenephthalide | Rattus norvegicus (Norway rat) | IC50 | 2.9000 | 1 | 1 |
| butylidenephthalide | Rattus norvegicus (Norway rat) | IC50 | 44.5000 | 1 | 1 |
| nerol | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| cannabidiol | Rattus norvegicus (Norway rat) | IC50 | 0.4500 | 1 | 1 |
| hc 030031 | Rattus norvegicus (Norway rat) | IC50 | 3.8500 | 2 | 2 |
| geranyl acetate | Rattus norvegicus (Norway rat) | IC50 | 21.2000 | 1 | 1 |
| pinosylvin | Rattus norvegicus (Norway rat) | IC50 | 12.1000 | 1 | 1 |
| Pinosylvin methyl ether | Rattus norvegicus (Norway rat) | IC50 | 6.9000 | 1 | 1 |
| pterostilbene | Rattus norvegicus (Norway rat) | IC50 | 7.5000 | 1 | 1 |
| shogaol | Rattus norvegicus (Norway rat) | IC50 | 16.7000 | 1 | 1 |
| 4,4'-dihydroxystilbene | Rattus norvegicus (Norway rat) | IC50 | 25.2000 | 1 | 1 |
| 4-hydroxystilbene | Rattus norvegicus (Norway rat) | IC50 | 5.5000 | 1 | 1 |
| cannabigerol | Rattus norvegicus (Norway rat) | IC50 | 13.0000 | 1 | 1 |
| 3,5-dimethoxy-trans-stilbene | Rattus norvegicus (Norway rat) | IC50 | 3.4000 | 1 | 1 |
| 3,4',5-trimethoxystilbene | Rattus norvegicus (Norway rat) | IC50 | 3.0000 | 1 | 1 |
| 4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime | Rattus norvegicus (Norway rat) | IC50 | 3.4000 | 1 | 1 |
| ly2183240 | Rattus norvegicus (Norway rat) | IC50 | 49.4000 | 1 | 1 |
| am 6701 | Rattus norvegicus (Norway rat) | IC50 | 11.2000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| hydrogen sulfide | Rattus norvegicus (Norway rat) | EC50 | 116.0000 | 1 | 1 |
| cannabinol | Rattus norvegicus (Norway rat) | EC50 | 0.1800 | 1 | 1 |
| allyl isothiocyanate | Rattus norvegicus (Norway rat) | EC50 | 3.4377 | 3 | 3 |
| thymol | Rattus norvegicus (Norway rat) | EC50 | 286.6000 | 1 | 1 |
| citronellol | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| citronellyl acetate | Rattus norvegicus (Norway rat) | EC50 | 12.2000 | 1 | 1 |
| dronabinol | Rattus norvegicus (Norway rat) | EC50 | 0.2300 | 1 | 1 |
| perillaldehyde | Rattus norvegicus (Norway rat) | EC50 | 30.2492 | 1 | 2 |
| cannabichromene | Rattus norvegicus (Norway rat) | EC50 | 17.1800 | 2 | 2 |
| perilla ketone | Rattus norvegicus (Norway rat) | EC50 | 30.2190 | 1 | 2 |
| cannabidiolic acid | Rattus norvegicus (Norway rat) | EC50 | 12.0000 | 1 | 1 |
| benzylidenephthalide | Rattus norvegicus (Norway rat) | EC50 | 3.0000 | 1 | 1 |
| nerol | Rattus norvegicus (Norway rat) | EC50 | 11.7000 | 1 | 1 |
| cannabidiol | Rattus norvegicus (Norway rat) | EC50 | 0.2880 | 2 | 2 |
| geranyl acetate | Rattus norvegicus (Norway rat) | EC50 | 25.8000 | 1 | 1 |
| Pinosylvin methyl ether | Rattus norvegicus (Norway rat) | EC50 | 3.5000 | 1 | 1 |
| pterostilbene | Rattus norvegicus (Norway rat) | EC50 | 3.6000 | 1 | 1 |
| shogaol | Rattus norvegicus (Norway rat) | EC50 | 16.0000 | 1 | 1 |
| 4,4'-dihydroxystilbene | Rattus norvegicus (Norway rat) | EC50 | 11.0000 | 1 | 1 |
| 4-hydroxy-2-nonenal | Rattus norvegicus (Norway rat) | EC50 | 24.6333 | 3 | 3 |
| 4-hydroxystilbene | Rattus norvegicus (Norway rat) | EC50 | 8.4000 | 1 | 1 |
| cannabigerol | Rattus norvegicus (Norway rat) | EC50 | 2.0500 | 2 | 2 |
| 3,5-dimethoxy-trans-stilbene | Rattus norvegicus (Norway rat) | EC50 | 1.7000 | 1 | 1 |
| 3,4',5-trimethoxystilbene | Rattus norvegicus (Norway rat) | EC50 | 1.7000 | 1 | 1 |
| ly2183240 | Rattus norvegicus (Norway rat) | EC50 | 26.9000 | 1 | 1 |
| cannabidivarin | Rattus norvegicus (Norway rat) | EC50 | 0.4200 | 1 | 1 |
| am 6701 | Rattus norvegicus (Norway rat) | EC50 | 20.1000 | 1 | 1 |