Page last updated: 2024-08-07 22:45:27

Chain A, RNA-directed RNA polymerase NS5

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (59)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
1-anilino-8-naphthalenesulfonateDengue virus 2 16681-PDK53IC50100.000010
ppm 18Dengue virus 2 16681-PDK53IC5018.460010
protoporphyrin ixDengue virus 2 16681-PDK53IC5034.590010
hematoxylinDengue virus 2 16681-PDK53IC5017.360010
n-(4-dimethylamino-3,5-dinitrophenyl)maleimideDengue virus 2 16681-PDK53IC5011.090010
aseanostatin p5Dengue virus 2 16681-PDK53IC5042.030010
NanaomycinDengue virus 2 16681-PDK53IC505.040010
2,3,4-trihydroxbenzophenoneDengue virus 2 16681-PDK53IC5057.660010
2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)diimino)bis-benzoic acidDengue virus 2 16681-PDK53IC5018.810010
lobaric acidDengue virus 2 16681-PDK53IC5032.190010
stictic acidDengue virus 2 16681-PDK53IC5071.170010
2-(4-hydroxyphenyl)-5,6,7,8-tetrahydroxy-4H-1-benzopyran-4-oneDengue virus 2 16681-PDK53IC50100.000010
4-chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acidDengue virus 2 16681-PDK53IC5058.300010
cryptotanshinoneDengue virus 2 16681-PDK53IC5090.060010
tanshinone ii aDengue virus 2 16681-PDK53IC50100.000010
fonsecinDengue virus 2 16681-PDK53IC5038.140010
1-Anilino-9,10-dioxo-2-anthroic acidDengue virus 2 16681-PDK53IC50100.000010
2-[(6-butoxy-3-pyridinyl)amino]-4-chlorobenzoic acidDengue virus 2 16681-PDK53IC5059.780010
5-(2-naphthalenylmethylidene)-1,3-diazinane-2,4,6-trioneDengue virus 2 16681-PDK53IC5050.800010
hematoxylinDengue virus 2 16681-PDK53IC5022.540010
2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinoneDengue virus 2 16681-PDK53IC505.230010
nsc668394Dengue virus 2 16681-PDK53IC5012.220010
4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)-5-dithiazolimineDengue virus 2 16681-PDK53IC50100.000010
6-ethyl-6-methyl-5,8-dihydro-1H-thiopyrano[2,3]thieno[2,4-b]pyrimidine-2,4-dioneDengue virus 2 16681-PDK53IC5088.670010
3-(4-methylbenzoyl)acrylic acidDengue virus 2 16681-PDK53IC50100.000010
3-chloro-1-(2-chlorophenyl)-4-(4-morpholinyl)pyrrole-2,5-dioneDengue virus 2 16681-PDK53IC5023.270010
umi-77Dengue virus 2 16681-PDK53IC505.015020
(4-chlorophenyl)-(5-hydroxy-2-methyl-4,6-dinitro-3-benzofuranyl)methanoneDengue virus 2 16681-PDK53IC5061.880010
N-[4-(4-fluorophenyl)-2-thiazolyl]-4-methylbenzenesulfonamideDengue virus 2 16681-PDK53IC5070.560010
3-(5,8-dinitro-1,3-dioxo-2-benzo[de]isoquinolinyl)benzoic acidDengue virus 2 16681-PDK53IC5026.670010
5-[(6-hydroxy-4-oxo-1-benzopyran-3-yl)methylidene]-1,3-diazinane-2,4,6-trioneDengue virus 2 16681-PDK53IC50100.000010
2-[(2,5-dimethylphenyl)sulfonylamino]-N-[4-(2-pyrimidinylsulfamoyl)phenyl]benzamideDengue virus 2 16681-PDK53IC50100.000010
2-[(5-chloro-2-thiophenyl)sulfonylamino]-N-(2-methoxy-5-methylphenyl)benzamideDengue virus 2 16681-PDK53IC5049.330010
2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrileDengue virus 2 16681-PDK53IC50100.000010
6-amino-4-(3-chlorophenyl)-3-methyl-1-(phenylmethyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrileDengue virus 2 16681-PDK53IC50100.000010
2-[(4-chlorophenyl)-[2-[5-(4-chlorophenyl)-2-thiazolyl]-5-methyl-3-oxo-1H-pyrazol-4-yl]methyl]propanedinitrileDengue virus 2 16681-PDK53IC5022.970010
2-[[3-methyl-5-oxo-1-(phenylmethyl)-4H-pyrazol-4-yl]-phenylmethyl]propanedinitrileDengue virus 2 16681-PDK53IC5055.360010
5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dioneDengue virus 2 16681-PDK53IC50100.000010
savirinDengue virus 2 16681-PDK53IC5051.500010
4-[(2-hydroxy-3-nitrophenyl)-(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyl]-5-methyl-2-phenyl-1H-pyrazol-3-oneDengue virus 2 16681-PDK53IC5031.560010
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidDengue virus 2 16681-PDK53IC5046.440010
1,8-dimethoxyphenazineDengue virus 2 16681-PDK53IC50100.000010
5-methyl-4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-(3-nitrophenyl)methyl]-2-phenyl-1H-pyrazol-3-oneDengue virus 2 16681-PDK53IC5052.870010
baicaleinDengue virus 2 16681-PDK53IC5035.060010
4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acidDengue virus 2 16681-PDK53IC5044.320010
mdl 105519Dengue virus 2 16681-PDK53IC5075.490010
5-amino-4-oxo-3-phenyl-1-thieno[3,4-d]pyridazinecarboxylic acidDengue virus 2 16681-PDK53IC5044.990010
1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazoleDengue virus 2 16681-PDK53IC5038.190010
[5-Chloranyl-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] ethanoateDengue virus 2 16681-PDK53IC5038.010010
5-chloro-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamideDengue virus 2 16681-PDK53IC50100.000010
5-chloro-2-[(3-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamideDengue virus 2 16681-PDK53IC5094.260010
5-chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(phenylmethyl)sulfonyl-4-pyrimidinecarboxamideDengue virus 2 16681-PDK53IC50100.000010
5-chloro-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-[(4-fluorophenyl)methylsulfonyl]-4-pyrimidinecarboxamideDengue virus 2 16681-PDK53IC5041.470010
acid blue 129Dengue virus 2 16681-PDK53IC5021.470010
sodium 2,6-dichloroindophenolDengue virus 2 16681-PDK53IC507.020010
flavoskyrinDengue virus 2 16681-PDK53IC5016.720010
hemateinDengue virus 2 16681-PDK53IC5026.520010
oosporeinDengue virus 2 16681-PDK53IC5028.290010
galloflavinDengue virus 2 16681-PDK53IC50100.000010