Page last updated: 2024-08-08 00:03:25

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8N183]

Synonyms

B17.2-like;
B17.2L;
Mimitin;
Myc-induced mitochondrial protein;
MMTN;
NDUFA12-like protein

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Compounds (2)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
auraptenHomo sapiens (human)IC5014.500022
marminHomo sapiens (human)IC5030.000022

Enables

This protein enables 2 target(s):

TargetCategoryDefinition
protein bindingmolecular functionBinding to a protein. [GOC:go_curators]
protein-containing complex bindingmolecular functionBinding to a macromolecular complex. [GOC:jl]

Located In

This protein is located in 2 target(s):

TargetCategoryDefinition
mitochondrioncellular componentA semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]
mitochondrial inner membranecellular componentThe inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. [GOC:ai]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
mitochondrioncellular componentA semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]

Involved In

This protein is involved in 2 target(s):

TargetCategoryDefinition
mitochondrial respiratory chain complex I assemblybiological processThe aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. [GOC:rph]
negative regulation of insulin secretion involved in cellular response to glucose stimulusbiological processAny process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. [GOC:BHF, GOC:dph]