Proteins > alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein
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alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (91)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3,4-dihydroxyphenylacetic acidHomo sapiens (human)IC50100.000010
tyrphostin a23Homo sapiens (human)IC509.970010
aloe emodinHomo sapiens (human)IC50100.000010
1-(3,4-dihydroxyphenyl)-2-(1-imidazolyl)ethanoneHomo sapiens (human)IC50100.000010
thioxoloneHomo sapiens (human)IC50100.000010
epicatechinHomo sapiens (human)IC500.407010
catechinHomo sapiens (human)IC5037.100010
5-(3-pyridyl)tetrazoleHomo sapiens (human)IC50100.000010
(R)-norlaudanosolineHomo sapiens (human)IC5010.100010
3-Hydroxy-1-(4-hydroxyphenyl)-1-propanoneHomo sapiens (human)IC50100.000010
calmidazoliumHomo sapiens (human)IC50100.000010
2-(5-amino-1-phenyl-1,2,4-triazol-3-yl)-3a,4,7,7a-tetrahydroisoindole-1,3-dioneHomo sapiens (human)IC50100.000010
LSM-32400Homo sapiens (human)IC5015.800010
1-(3,4-dihydroxyphenyl)-2-[[5-(2-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)IC5072.400010
1-(3,4-dihydroxyphenyl)-2-[(4,6-dimethyl-2-pyrimidinyl)thio]ethanoneHomo sapiens (human)IC507.185010
3-(2-methylpropylthio)-1H-1,2,4-triazol-5-amineHomo sapiens (human)IC5060.800010
LSM-16463Homo sapiens (human)IC50100.000010
curcuminHomo sapiens (human)IC50100.000010
4-[2-(3-methoxyanilino)-4-thiazolyl]phenolHomo sapiens (human)IC50100.000010
4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]benzoic acid methyl esterHomo sapiens (human)IC50100.000010
4-(2-methoxyphenoxy)-N-(3-pyridinyl)benzenesulfonamideHomo sapiens (human)IC50100.000010
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)IC50100.000010
2-[[5-(3-chlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanoneHomo sapiens (human)IC5020.700010
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)IC5017.800010
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)IC50100.000010
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)IC5017.400010
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanoneHomo sapiens (human)IC50100.000010
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-oneHomo sapiens (human)IC50100.000010
2,5-dimethoxy-n-(quinolin-3-yl)benzenesulfonamideHomo sapiens (human)IC500.358830
4-ethoxy-N-(3-quinolinyl)benzenesulfonamideHomo sapiens (human)IC50100.000010
2-(5-phenyl-1H-1,2,4-triazol-3-yl)-3a,4,7,7a-tetrahydroisoindole-1,3-dioneHomo sapiens (human)IC500.556510
3-(4-bromophenyl)-1H-pyrazole-5-carboxylic acid methyl esterHomo sapiens (human)IC5050.570020
7-methoxy-4,5-dihydro-2H-benzo[g]indazole-3-carboxylic acidHomo sapiens (human)IC503.165020
1-(4-chlorophenyl)-3-[2-(2-furanylmethyl)cyclohexyl]ureaHomo sapiens (human)IC50100.000010
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidHomo sapiens (human)IC50100.000010
quercetin 3-o-glucopyranosideHomo sapiens (human)IC5014.000010
sulfuretinHomo sapiens (human)IC5052.900010
myricetinHomo sapiens (human)IC5033.200010
ag 538Homo sapiens (human)IC5054.745020
tyrphostin ag 555Homo sapiens (human)IC505.160010
thunberginol bHomo sapiens (human)IC5019.500010
3,3'-diethylthiacarbocyanine iodideHomo sapiens (human)IC5074.800010
levodopa methyl ester hydrochloride, (dl)-isomerHomo sapiens (human)IC50100.000010
DihydroroseosideHomo sapiens (human)IC50100.000010
phenylalanine betaineHomo sapiens (human)IC5060.400010
5-fluoro-2-phenyl-1,2-benzothiazol-3-oneHomo sapiens (human)IC50100.000010
2-(4-fluorophenyl)-1,2-benzothiazol-3-oneHomo sapiens (human)IC50100.000010
N-[(2-ethoxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamideHomo sapiens (human)IC5022.700010
catechinHomo sapiens (human)IC50100.000010

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
hematoxylinHomo sapiens (human)EC5085.700010
eriodictyolHomo sapiens (human)EC5081.800010
benserazide hydrochlorideHomo sapiens (human)EC50100.000010
sulconazole, mononitrate, (+-)-isomerHomo sapiens (human)EC5060.314010
miconazole nitrateHomo sapiens (human)EC5070.585010
2,2',2''-terpyridineHomo sapiens (human)EC5027.500010
3-aminophenoxazoneHomo sapiens (human)EC5074.500010
3-(n-salicyloyl)amino-1,2,4-triazoleHomo sapiens (human)EC509.630010
2-(4-hydroxyphenyl)-5,6,7,8-tetrahydroxy-4H-1-benzopyran-4-oneHomo sapiens (human)EC5043.400010
5,5,7,12,12,14-hexamethyl-1,4,8,11-tetrazacyclotetradecaneHomo sapiens (human)EC505.850010
sch 45752Homo sapiens (human)EC5026.700010
2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamideHomo sapiens (human)EC504.170010
3,5-dimethoxy-N-(1H-1,2,4-triazol-5-yl)benzamideHomo sapiens (human)EC503.820010
2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamideHomo sapiens (human)EC5028.076020
3-fluoro-N-(1H-1,2,4-triazol-5-yl)benzamideHomo sapiens (human)EC507.895010
1-[[(1,3-dimethyl-4-pyrazolyl)-oxomethyl]amino]-3-(4-methylphenyl)thioureaHomo sapiens (human)EC5032.297330
3,4,5-triethoxy-N-(1H-1,2,4-triazol-5-yl)benzamideHomo sapiens (human)EC504.620010
1-[[(5-bromo-2-furanyl)-oxomethyl]amino]-3-(2,5-dimethylphenyl)thioureaHomo sapiens (human)EC5025.465030
N-(2,6-dimethylphenyl)-2-[(6-methoxy-2-methyl-4-quinolinyl)thio]acetamideHomo sapiens (human)EC50100.000010
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)EC5068.000010
1-ethyl-3-[[[2-(2-methylpropyl)-4-quinolinyl]-oxomethyl]amino]thioureaHomo sapiens (human)EC5063.019010
2-methyl-N-[[[oxo-(3,4,5-trimethoxyphenyl)methyl]hydrazo]-sulfanylidenemethyl]benzamideHomo sapiens (human)EC5040.500010
4-chloro-N-[[[oxo-(3,4,5-trimethoxyphenyl)methyl]hydrazo]-sulfanylidenemethyl]benzamideHomo sapiens (human)EC5029.400010
1-ethyl-3-[[[(phenylmethyl)amino]-sulfanylidenemethyl]amino]thioureaHomo sapiens (human)EC5015.593230
1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thioureaHomo sapiens (human)EC5021.100010
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanoneHomo sapiens (human)EC5064.200010
3-(1-azepanylsulfonyl)-4-chloro-N-(1H-1,2,4-triazol-5-yl)benzamideHomo sapiens (human)EC504.570010
4-chloro-3-[(4-chlorophenyl)sulfamoyl]-N-(1H-1,2,4-triazol-5-yl)benzamideHomo sapiens (human)EC5071.300010
4,5-dimethyl-2-[[1-oxo-2-(4-quinazolinyloxy)ethyl]amino]-3-thiophenecarboxylic acid ethyl esterHomo sapiens (human)EC50100.000010
1-(4-fluorophenyl)-3-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]pyrrolidine-2,5-dioneHomo sapiens (human)EC50100.000010
2-[(4-methylphenyl)thio]-N-(1H-1,2,4-triazol-5-yl)propanamideHomo sapiens (human)EC503.660010
N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamideHomo sapiens (human)EC5013.250020
3-methyl-4-nitro-N-(1H-1,2,4-triazol-5-yl)benzamideHomo sapiens (human)EC507.600010
5-chloro-7-[1-piperidinyl(2-pyridinyl)methyl]-8-quinolinolHomo sapiens (human)EC5081.148010
N1',N6'-bis[(5-methyl-1H-pyrazol-3-yl)-oxomethyl]hexanedihydrazideHomo sapiens (human)EC5015.494010
LSM-16912Homo sapiens (human)EC50100.000010
N-[1-[1-[2-[4-(diethylamino)anilino]-2-oxoethyl]-2-benzimidazolyl]ethyl]-4-methylbenzamideHomo sapiens (human)EC50100.000010
5'-bromo-2'-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-1H-indole]oneHomo sapiens (human)EC500.567850
N-[3-[(4-chlorophenyl)methylthio]-1H-1,2,4-triazol-5-yl]-4-cyanobenzamideHomo sapiens (human)EC5086.800010
N-[3-(diethylamino)propyl]-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamideHomo sapiens (human)EC5017.889730
xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-GlucopyranosideHomo sapiens (human)EC5057.600010
N-[2-[1-[(4-methoxy-3-methylphenyl)methyl]-4-piperidinyl]-3-pyrazolyl]-4-phenylbutanamideHomo sapiens (human)EC5070.100010
N-[(2-ethoxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamideHomo sapiens (human)EC50100.000010
2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-6-(methoxymethyl)-1H-pyrimidin-4-oneHomo sapiens (human)EC5015.503330
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-(3-fluorophenyl)acetamideHomo sapiens (human)EC5025.109330