A dipeptidyl peptidase 4 that is encoded in the genome of rat. [OMA:P14740, PRO:DNx]
EC 3.4.14.5;
Bile canaliculus domain-specific membrane glycoprotein;
Dipeptidyl peptidase IV;
DPP IV;
GP110 glycoprotein;
T-cell activation antigen CD26
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cisapride | Rattus norvegicus (Norway rat) | IC50 | 2.6900 | 1 | 1 |
| fluoxetine | Rattus norvegicus (Norway rat) | Ki | 7.3000 | 1 | 1 |
| imatinib | Rattus norvegicus (Norway rat) | IC50 | 5.0000 | 1 | 1 |
| terfenadine | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
| trimethoprim | Rattus norvegicus (Norway rat) | IC50 | 2.7000 | 1 | 1 |
| staurosporine | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| piritrexim | Rattus norvegicus (Norway rat) | IC50 | 0.0110 | 1 | 1 |
| epiroprim | Rattus norvegicus (Norway rat) | IC50 | 0.4800 | 1 | 1 |
| sori 8895 | Rattus norvegicus (Norway rat) | IC50 | 0.0160 | 1 | 1 |
| ag-213 | Rattus norvegicus (Norway rat) | IC50 | 38.0000 | 1 | 1 |
| 3,3',4,5'-tetrahydroxystilbene | Rattus norvegicus (Norway rat) | IC50 | 38.0000 | 1 | 1 |
| sitagliptin | Rattus norvegicus (Norway rat) | IC50 | 0.0255 | 2 | 2 |
| genistein | Rattus norvegicus (Norway rat) | IC50 | 39.0000 | 1 | 1 |
| vildagliptin | Rattus norvegicus (Norway rat) | IC50 | 14.2190 | 1 | 1 |
| nvp-dpp728 | Rattus norvegicus (Norway rat) | IC50 | 2.2877 | 2 | 2 |
| ucn 1028 c | Rattus norvegicus (Norway rat) | IC50 | 1.1000 | 1 | 1 |
| 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one | Rattus norvegicus (Norway rat) | IC50 | 0.0410 | 1 | 1 |