A methionine aminopeptidase that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AE18]
MAP;
MetAP;
EC 3.4.11.18;
Peptidase M
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| albendazole | Escherichia coli K-12 | IC50 | 10.0000 | 1 | 1 |
| fenbendazole | Escherichia coli K-12 | IC50 | 10.0000 | 1 | 1 |
| mebendazole | Escherichia coli K-12 | IC50 | 10.0000 | 1 | 1 |
| thiabendazole | Escherichia coli K-12 | IC50 | 0.4720 | 1 | 1 |
| 2-(2'-hydroxyphenyl)benzimidazole | Escherichia coli K-12 | IC50 | 10.0000 | 1 | 1 |
| fuberidazole | Escherichia coli K-12 | IC50 | 10.0000 | 1 | 1 |
| carbendazim | Escherichia coli K-12 | IC50 | 10.0000 | 1 | 1 |
| 2-(2'-pyridyl)benzimidazole | Escherichia coli K-12 | IC50 | 0.5740 | 1 | 1 |
| pyridine-2-carboxylic acid thiazol-2-ylamide | Escherichia coli K-12 | IC50 | 5.0000 | 4 | 4 |
| fumagillin | Escherichia coli K-12 | IC50 | 100.0000 | 1 | 1 |