A DNA topoisomerase 4 subunit A that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AFI2]
EC 5.6.2.2;
Topoisomerase IV subunit A
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ciprofloxacin | Escherichia coli K-12 | IC50 | 51.0000 | 1 | 1 |
| novobiocin | Escherichia coli K-12 | Ki | 0.0447 | 1 | 3 |