Compounds > ribavirin
Page last updated: 2024-08-16

ribavirin and Sensitivity and Specificity

ribavirin has been researched along with Sensitivity and Specificity in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (5.26)18.2507
2000's57 (50.00)29.6817
2010's49 (42.98)24.3611
2020's2 (1.75)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Linjie, L; Lutao, X; Pin, L; Qunjie, P; Wang, D; Weijun, F1
Abravanel, F; Carrere, N; Delobel, P; Dubois, M; Izopet, J; Kamar, N; Lhomme, S; Marion, O; Migueres, M; Nayrac, M; Peron, JM; Pucelle, M; Requena, M; Suc, B1
Cheng, K; Chevaliez, S; Cloherty, G; Cohen, DE; Dawson, GJ; Feld, JJ; Hackett, J; Herman, C; Maasoumy, B; Pawlotsky, JM; Rockstroh, JK; Sarrazin, C; Wedemeyer, H1
Applegate, TL; Backmund, M; Bruggmann, P; Cloherty, G; Conway, B; Cunningham, EB; Cunningham, P; Dalgard, O; Dore, GJ; Foster, GR; Grebely, J; Hajarizadeh, B; Lamoury, FMJ; Marks, P; Martinez, D; Robaeys, G; Soker, A; Swan, T1
GeurtsvanKessel, CH; Hullegie, SJ; Ramakers, C; Rijnders, BJA; van der Eijk, AA1
Chang, F; Duan, CA; Jin, X; Lu, Y1
Baker, MM; Belal, TS; Hammad, SF1
Beijnen, JH; Huitema, AD; Kromdijk, W; Mulder, JW; Pereira, SA; Rosing, H1
Hsiao, CC; Hu, TH; Hung, CH; Kee, KM; Lee, CM; Lu, SN; Wang, JC; Wang, JH; Yen, YH1
Bikharam, D; Musarat, K; Samiullah, S1
Aziz, S; Mirza, T; Sohail, S1
Andréjak, M; Bodeau, S; Brochot, E; Castelain, S; Durand-Maugard, C; Duverlie, G; François, C; Helle, F; Lemaire-Hurtel, AS; Nguyen-Khac, E1
Anderson, PL; Bushman, LR; Jimmerson, LC; Kiser, JJ; MacBrayne, CE; Zheng, JH1
Barrero Alor, F; Casado Monge, PG; Jiménez Macías, FM; Pujol de la Llave, E; Ramos Lora, M; Ruíz-Frutos, C1
Bernstein, B; Chevaliez, S; Cloherty, G; Cohen, D; Herman, C; Pawlotsky, JM; Sarrazin, C; Wedemeyer, H1
Anderson, PL; Bushman, LR; Jimmerson, LC; Kiser, JJ; Klein, B; Ray, ML; Rower, JE; Zheng, JH1
Chi, B; Li, M; Liu, DW; Wang, J; Wu, XX; Zheng, H1
Andersson, K; Avorn, J; Brennan, T; Choudhry, NK; Krumme, AA; Matlin, OS; Najafzadeh, M; Shrank, WH1
Athanasakis, K; Ferrante, SA; Hill, M; Kyriopoulos, II; Kyriopoulos, J; Petrakis, I; Retsa, MP1
Adinolfi, LE; Alessio, L; Boemio, A; Coppola, N; Grandone, A; Marrone, A; Minichini, C; Pisaturo, M; Sagnelli, E; Stanzione, M; Starace, M; Zampino, R1
Capobianchi, MR; Castiglione, F; D'Offizi, G; Garbuglia, AR; Lapa, D; Lionetti, R; Montalbano, M; Paci, P; Taibi, C; Visco-Comandini, U1
Bjøro, K; Dalgard, O; Marcellin, P; Martinot-Peignoux, M; Ring-Larsen, H; Verbaan, H1
Chen, XH; Gao, L; Geng, JB; Hao, KY; Li, P; Wang, J; Wang, M; Wang, MR; Wang, SM; Xie, F; Xiong, X; Yang, ZG; Zhang, X; Zheng, WK1
Baboe, F; de Jongh, E; Griffioen-Keijzer, A; Hoppe, BP; IJzerman, EP; Zijlstra-Baalbergen, JM1
Bodeau, S; Brochot, E; Diouf, M; Duverlie, G; Lemouel, JP; Nguyen-Khac, E1
Chen, W; Dang, P; Feng, J; Ma, Y; Wang, L; Xi, W; Yu, Y1
Hmwe, SS; Ide, T; Inoue, T; Kato, K; Kumada, T; Shimada, N; Takaguchi, K; Tanaka, Y; Torimura, T; Toyoda, H; Tsubota, A; Wakita, T1
El-Shamy, A; Hayashi, Y; Hotta, H; Imoto, S; Kawada, N; Kim, KI; Kim, SR; Kudo, M; Mita, K; Sasase, N; Shouji, I; Taniguchi, M1
Gagnieu, MC; Maynard, M; Pradat, P; Souvignet, C; Trepo, C1
Ackermann, O; Grigorian, N; Herrmann, E; Hofmann, WP; Lengauer, T; Mihm, U; Sarrazin, C; Welker, MW; Welsch, C; Zeuzem, S1
Benhamou, Y; Kaita, KD; McHutchison, JG; Patel, K; Pulkstenis, E; Subramanian, GM; Torbenson, M; Yoshida, EM; Zeuzem, S1
Akiyama, T; Ario, K; Eguchi, Y; Hisatomi, A; Kawaguchi, Y; Kuwashiro, T; Mizuta, T; Otsuka, T; Oza, N; Ozaki, I; Takahashi, H; Yoshimura, T1
Aberle, JH; Gangl, A; Holzmann, H; Kohrgruber, N; Kundi, M; Peck-Radosavljevic, M; Reiberger, T; Rieger, A1
Meléndez, M; Rodríguez, JF; Rosario, O; Zayas, B1
Aidelsburger, P; Manns, MP; McHutchison, JG; Rossol, S; Siebert, U; Sroczynski, G; Wasem, J; Wong, JB1
Babany, G; Canva-Delcambre, V; Deltenre, P; Deuffic-Burban, S; Dharancy, S; Lonjon-Domanec, I; Louvet, A; Mathurin, P; Roudot-Thoraval, F1
Chanu, P; Frey, N; Goggin, T; Grippo, J; Jacqmin, P; Jonsson, EN; Jorga, K; Jumbe, NL; Lavielle, M; Snoeck, E1
Angelico, M; Baiocchi, L; Carbone, M; Conti, RL; Cucchiarelli, S; De Leonardis, F; Delle Monache, M; Di Paolo, D; Lenci, I; Nosotti, L1
Adams, LA; Bulsara, M; Cheng, W; Flexman, JP; Lee, S; Price, P; Rossi, E; Varano, J; Watson, MW1
Altomare, E; Antonaci, S; Batini, I; Capria, A; Giannelli, G; Grandi, B; Guarducci, I; Marsi, O; Moscato, GA; Pellegrini, G; Pieri, D; Sacco, R1
Alberti, A; Bortoletto, G; Campagnolo, D; Comastri, G; Mirandola, S; Pulvirenti, FR; Severini, L1
Afendy, A; Baranova, A; Limongi, D; Liotta, L; Mehta, R; Petricoin, E; Pierobon, M; Stepanova, M; Younossi, ZM1
Chayama, K; Hayes, CN; Hiasa, Y; Izumi, N; Kumada, H; Matsumoto, A; Moriwaki, H; Nomura, H; Okanoue, T; Oketani, M; Sakisaka, S; Seike, M; Takehara, T; Toyota, J; Ueno, Y; Yoshioka, K; Yotsuyanagi, H1
De Knegt, RJ; Desombere, I; Haagmans, B; Hansen, B; Janssen, HL; Leroux-Roels, G; Orlent, H; Schalm, SW; Van Vlierberghe, H1
Ichijo, T; Joshita, S; Kamijo, A; Katsuyama, Y; Komatsu, M; Matsumoto, A; Ota, M; Tanaka, E; Umemura, T; Yoneda, S; Yoshizawa, K1
Carnauba, D; Damas, C; Diaz, RS; Dos Santos, CV; El-Far, F; Ferraz, ML; Reis, A; Santos, C; Serra, F; Silva, MH; Viana, MV1
Asahina, Y; Enomoto, N; Hoshioka, Y; Hosokawa, T; Itakura, J; Izumi, N; Katoh, T; Kurosaki, M; Muraoka, M; Nakanishi, H; Nitta, S; Sakamoto, N; Suzuki, Y; Takahashi, Y; Tamaki, N; Tanaka, K; Tsuchiya, K; Ueda, K; Yasui, Y1
Lesesne, SB; Patel, N; Rein, DB; Roblin, DW; Smith, BD; Wagner, LD; Ward, JW; Weinbaum, CM; Wittenborn, JS1
Ebinuma, H; Hibi, T; Kanai, T; Ojiro, K; Saito, H; Tada, S; Takayama, T; Wakabayashi, K; Yamagishi, Y1
Hamzeh, FM; Jensen, D; Lentz, E; Reau, N; Zhou, X1
Alffenaar, JW; Greijdanus, B; Kok, WT; Uges, DR; van der Lijke, H1
Cheiab, B; Ioniţă-Radu, F; Raşcanu, A1
Barnes, E; Brown, A; Christian, A; Collier, JD; Foster, GR; Hibbert, L; Humphreys, IS; Klenerman, P; Rahman, M; von Delft, A1
Imawari, M; Kato, T; Masaki, T; Matsumura, T; Murayama, A; Sugiyama, N; Tasaka-Fujita, M; Wakita, T1
Akuta, N; Arase, Y; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Saitoh, S; Seko, Y; Sezaki, H; Suzuki, F; Suzuki, Y1
Beinhardt, S; Ferenci, P; Rutter, K; Stättermayer, AF1
Ginba, H; Ide, T; Izumi, N; Kumada, T; Matsuyama, K; Sata, M; Shimada, N; Takaguchi, K; Toyoda, H1
Aghemo, A; Degasperi, E; Facchetti, F; Galmozzi, E; Lampertico, P1
Cen, S; He, Z; Li, XY; Liu, ZL; Wang, X; Wang, Z; Wei, XL; Yin, X; Zhang, ZZ; Zhou, JM1
Lau, JY; Lin, CC; Yeh, LT1
Kurth, BM; Manns, MP; McHutchison, JG; Ravens-Sieberer, U; Rossol, S; Siebert, U; Sroczynski, G; Wasem, J; Wong, JB1
Buti, M; Cabasés, JM; Guillén-Grima, F; Mar, J; San Miguel, R1
Buti, M; Casado, MA; Esteban, R; Fosbrook, L; Medina, M; Wong, JB1
Belli, L; Civardi, E; Leveri, M; Marinelli, D; Rossi, L; Silini, EM1
Guntz, P; Lunel, F; Maniez-Montreuil, M; Payan, C; Picchio, G; Veillon, P1
Al-Jaser, NM; Serebour, FE; Shobokshi, OA; Skakni, LI1
Courcambeck, J; Halfon, P; Joly, H; Khiri, H; Ouzan, D; Pénaranda, G; Tran, A1
Castéra, L; Couzigou, P; de Lédinghen, V; Fleury, H; Foucher, J; Trimoulet, P1
Germer, JJ; Hoskin, TL; Metwally, MA; Patel, R; Scott Harmsen, W; Smith, TF; Zein, NN1
Alberti, A; Craxi, A; De Carli, C; Giuliani, G; Green, J; Patel, KK; Sullivan, SD; Wintfeld, N1
Benoni, G; Corrocher, R; Cuzzolin, L; Gabrielli, GB; Pasino, M; Perfetti, P; Stanzial, AM1
Acosta, L; Ballesteros, AL; Clotet, B; Franco, S; Fuster, D; Martínez, MA; Planas, R; Rey-Joly, C; Salas, A; Sirera, G; Tor, J; Tural, C1
Fried, MW1
Cozzolongo, R; Maiellaro, PA; Marino, P1
Colombo, M; Del Ninno, E; Parravicini, ML; Ronchi, G; Rumi, MG; Russo, A; Soffredini, R1
Chiu, WK; Leung, CW1
Akuta, N; Arase, Y; Hosaka, T; Ikeda, K; Kobayashi, M; Kumada, H; Saitoh, S; Someya, T; Suzuki, F; Suzuki, Y; Tsubota, A1
Carlson, EJ; Ferrin, TE; Giacomini, KM; Gray, JH; Huang, CC; Johns, SJ; Kawamoto, M; Owen, RP; Stryke, D; Taylor, TR1
Lin, CC; Lourenco, D; Nguyen, M; Yeh, LT1
Buti, M; Casado, MA; Esteban, R; Fosbrook, L1
Fukuoka, M; Hata, T; Kudo, M; Kuwano, H; Kuwao, H; Moriyama, K; Naitoh, S; Nomura, M; Tohda, Y1
Lim, C; Lin, CC; Liu, Y; Xu, C; Yan, R; Yeh, LT1
Bonora, S; D'Avolio, A; de Requena, DG; Di Perri, G; Ibañez, A; Sciandra, M; Siccardi, M1
Athill, L; Ke, J; Li, S; Li, W; Luo, S; Ray, T; Smith, HT; Tse, FL; Wu, A; Zhou, W1
Artioli, S; Azzola, E; Basso, M; Blanchi, S; Grasso, A; Pelli, N; Percario, G; Picciotto, A; Torre, F1
Akuta, N; Arase, Y; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Sezaki, H; Suzuki, F; Suzuki, Y; Yatsuji, H1
Dhillon, AP; Ferrari, C; Haagmans, BL; Hellstrand, K; Lagging, M; Missale, G; Negro, F; Neumann, AU; Norkrans, G; Pawlotsky, JM; Romero, AI; Schalm, SW; Verheij-Hart, E; von Wagner, M; Westin, J; Zeuzem, S1
Akuta, N; Kobayashi, M; Kumada, H; Matsuo, Y; Okamoto, K; Tazawa, H1
Karandikar, NJ; Lee, WM; Pillai, V; Thiele, DL1
Han, HY; Kohli, E; Vinogradov, SV; Zeman, AD1
Loregian, A; Pagni, S; Palù, G; Parisi, SG; Scarpa, MC1
Chang, WY; Chen, SC; Chuang, WL; Dai, CY; Hou, NJ; Hsieh, MY; Huang, JF; Lee, LP; Lin, ZY; Wang, LY; Yang, JF; Yu, ML1
Buti, M; Casado, MA; Esteban, R1
Akazawa, K; Aoyagi, Y; Kobayashi, K; Nakamura, J; Toyabe, S1
Cantillano, AL; González-Pardo, G; Jiménez, I; Morello, J; Rodríguez-Nóvoa, S; Soriano, V1
Bonura, C; Craxì, A; Di Marco, V; Di Stefano, R; Ferraro, D; Giglio, M; Mondelli, MU1
Gotoh, T; Hiramatsu, K; Joh, T; Kani, S; Matsuura, K; Mizokami, M; Takagi, K; Tanaka, Y; Wakimoto, Y1
Carlsson, T; Quist, A; Weiland, O1
Alsiö, A; Buhl, MR; Dhillon, AP; Färkkilä, M; Hellstrand, K; Lagging, M; Langeland, N; Mørch, K; Norkrans, G; Pedersen, C; Westin, J1
Ijichi, K; Inoue, H; Konno, K; Shigeta, S; Watanabe, W; Yokota, T1
Bofill, M; Fairbanks, LD; Ruckemann, K; Simmonds, HA1
Chan, CY; Co, RL; Hwang, SJ; Lai, L; Lee, SD; Lu, RH; Tong, MJ1
Collins, ML; Davis, GL; Detmer, J; Kolberg, JA; Lau, JY; Mizokami, M; Orito, E; Qian, K; Urdea, MS1
McHutchison, JG; Shermock, KM; Singer, ME; Younossi, ZM1
Albrecht, JK; Ling, MH; Pauker, SG; Poynard, T; Wong, JB1
Altisent, C; Esteban, JI; Esteban, R; Guardia, J; Puig, L; Sauleda, S1
Brabant, G; Horn, R; Jaeckel, E; Manns, MP; Ockenga, J; Tillmann, HL; von zur Mühlen, A; Wedemeyer, H; Widjaja, A1
Csef, H; Faller, H; Kraus, MR; Mörk, H; Schäfer, A; Scheurlen, M1
Rosenberg, W; Stein, K; Wong, J1
Langner, RG; van Leeuwen, DJ; Yee, LJ1
Allende, H; Castro, FJ; Esteban, JI; Esteban, R; Guardia, J; Juárez, A; Martell, M; Moreno, F; Sauleda, S; Viladomiu, L1
Changchien, CS; Chen, TM; Huang, WS; Hung, CH; Lee, CM; Lu, SN; Tung, HD; Wang, JH1
Jayaram, HN; Weber, G; Zhen, W1

Reviews

7 review(s) available for ribavirin and Sensitivity and Specificity

ArticleYear
IL28B rs12980275 variant as a predictor of sustained virologic response to pegylated-interferon and ribavirin in chronic hepatitis C patients: A systematic review and meta-analysis.
    Clinics and research in hepatology and gastroenterology, 2015, Volume: 39, Issue:5

    Topics: Antiviral Agents; Biomarkers; Disease Progression; Drug Therapy, Combination; Gene Expression Regulation; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferons; Interleukins; Polyethylene Glycols; Polymorphism, Single Nucleotide; Predictive Value of Tests; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome; Viral Load

2015
Human metapneumovirus in haematopoietic stem cell transplantation recipients: a case series and review of the diagnostic and therapeutic approach.
    The Netherlands journal of medicine, 2016, Volume: 74, Issue:8

    Topics: Aged; Antiviral Agents; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Immunologic Factors; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Male; Metapneumovirus; Middle Aged; Multiple Myeloma; Multiplex Polymerase Chain Reaction; Nasopharynx; Paramyxoviridae Infections; Respiratory Tract Infections; Ribavirin; RNA, Viral; Sensitivity and Specificity

2016
IL28B polymorphism -- predictive factor of HCV infected genotype 1 individuals to treatment response and management of therapy.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2011, Volume: 49, Issue:2

    Topics: Antiviral Agents; Biomarkers; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C; Humans; Interferon-alpha; Interferons; Interleukins; Oligopeptides; Polyethylene Glycols; Polymorphism, Genetic; Predictive Value of Tests; Proline; Recombinant Proteins; Ribavirin; Risk Assessment; Sensitivity and Specificity; Treatment Outcome

2011
The role of the laboratory in the diagnosis and management of chronic hepatitis C patients.
    Saudi medical journal, 2003, Volume: 24 Suppl 2

    Topics: Acute Disease; Biopsy, Needle; Clinical Laboratory Techniques; Enzyme-Linked Immunosorbent Assay; Female; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; Hepatitis C, Chronic; Humans; Immunohistochemistry; Interferon alpha-2; Interferon-alpha; Male; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Saudi Arabia; Sensitivity and Specificity

2003
Viral factors affecting the outcome of therapy for chronic hepatitis C.
    Reviews in gastroenterological disorders, 2004, Volume: 4 Suppl 1

    Topics: Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Pharmacogenetics; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Risk Assessment; RNA, Viral; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Viral Load

2004
Clinical picture, diagnosis, treatment and outcome of severe acute respiratory syndrome (SARS) in children.
    Paediatric respiratory reviews, 2004, Volume: 5, Issue:4

    Topics: Antiviral Agents; Humans; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Sensitivity and Specificity; Severe Acute Respiratory Syndrome; Tomography, X-Ray Computed

2004
Financial impact of two different ways of evaluating early virological response to peginterferon-alpha-2b plus ribavirin therapy in treatment-naive patients with chronic hepatitis C virus genotype 1.
    PharmacoEconomics, 2005, Volume: 23, Issue:10

    Topics: Antiviral Agents; Decision Trees; Drug Therapy, Combination; Economics, Pharmaceutical; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Multicenter Studies as Topic; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Spain

2005

Trials

15 trial(s) available for ribavirin and Sensitivity and Specificity

ArticleYear
HCV core antigen as an alternate test to HCV RNA for assessment of virologic responses to all-oral, interferon-free treatment in HCV genotype 1 infected patients.
    Journal of virological methods, 2017, Volume: 245

    Topics: 2-Naphthylamine; Administration, Oral; Adult; Aged; Antiviral Agents; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Interferons; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Retrospective Studies; Ribavirin; Ritonavir; RNA, Viral; Sensitivity and Specificity; Sulfonamides; Uracil; Viral Load

2017
HCV RNA assay sensitivity impacts the management of patients treated with direct-acting antivirals.
    Antiviral therapy, 2015, Volume: 20, Issue:2

    Topics: 2-Naphthylamine; Antiviral Agents; Biological Assay; Cyclopropanes; Drug Monitoring; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Lactams, Macrocyclic; Macrocyclic Compounds; Oligopeptides; Polyethylene Glycols; Proline; Reagent Kits, Diagnostic; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Sulfonamides; Treatment Outcome; Uracil; Viral Load

2015
Clinical Significance of Two Real-Time PCR Assays for Chronic Hepatitis C Patients Receiving Protease Inhibitor-Based Therapy.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aged; Antiviral Agents; Cell Line; Drug Synergism; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Protease Inhibitors; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Transfection; Treatment Outcome; Viral Load; Viremia

2017
An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
    Journal of viral hepatitis, 2009, Volume: 16, Issue:3

    Topics: Adult; Albumins; Antiviral Agents; Biomarkers; Biopsy; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver; Liver Cirrhosis; Male; Middle Aged; Reagent Kits, Diagnostic; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome

2009
Clinical effectiveness and cost effectiveness of tailoring chronic hepatitis C treatment with peginterferon alpha-2b plus ribavirin to HCV genotype and early viral response: a decision analysis based on German guidelines.
    PharmacoEconomics, 2009, Volume: 27, Issue:4

    Topics: Adult; Antiviral Agents; Cost of Illness; Cost-Benefit Analysis; Decision Support Techniques; Drug Therapy, Combination; Female; Genotype; Germany; Guidelines as Topic; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Life Expectancy; Male; Markov Chains; Polyethylene Glycols; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Sensitivity and Specificity

2009
Baseline anti-NS4a antibodies in combination with on-treatment quantitative HCV-RNA reliably identifies nonresponders to pegylated interferon-ribavirin combination therapy after 4 weeks of treatment.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:12

    Topics: Adult; Aged; Algorithms; Antiviral Agents; Biomarkers; Carrier Proteins; Decision Support Techniques; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; Humans; Interferon alpha-2; Interferon-alpha; Intracellular Signaling Peptides and Proteins; Logistic Models; Male; Middle Aged; Patient Selection; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Reproducibility of Results; Ribavirin; RNA, Viral; Sensitivity and Specificity; Time Factors; Treatment Failure; Viral Nonstructural Proteins; Young Adult

2010
Prediction of effect of pegylated interferon alpha-2b plus ribavirin combination therapy in patients with chronic hepatitis C infection.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Models, Statistical; Neural Networks, Computer; Polyethylene Glycols; Recombinant Proteins; Regression Analysis; Reproducibility of Results; Ribavirin; ROC Curve; Sensitivity and Specificity

2011
Cost effectiveness of peginterferon alpha-2b plus ribavirin versus interferon alpha-2b plus ribavirin for initial treatment of chronic hepatitis C.
    Gut, 2003, Volume: 52, Issue:3

    Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Health Care Costs; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Life Expectancy; Male; Markov Chains; Middle Aged; Polyethylene Glycols; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Survival Analysis

2003
Early viral kinetics and treatment outcome in combination of high-dose interferon induction vs. pegylated interferon plus ribavirin for naive patients infected with hepatitis C virus of genotype 1b and high viral load.
    Journal of medical virology, 2005, Volume: 75, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Viral Load

2005
Pegylated interferon and ribavirin in re-treatment of responder-relapser HCV patients.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2007, Volume: 39, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Recurrence; Retreatment; Ribavirin; RNA, Viral; Sensitivity and Specificity; Time Factors; Treatment Outcome; White People

2007
Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: amino acid substitutions in the core region and low-density lipoprotein cholesterol l
    Journal of hepatology, 2007, Volume: 46, Issue:3

    Topics: Adult; Aged; Amino Acid Substitution; Antiviral Agents; Cholesterol, LDL; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Japan; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome; Viral Core Proteins

2007
IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6

    Topics: Adult; Body Mass Index; Chemokine CXCL10; Chemokines, CXC; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome

2006
Randomized comparison of 12 or 24 weeks of peginterferon alpha-2a and ribavirin in chronic hepatitis C virus genotype 2/3 infection.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:6

    Topics: Adult; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome

2008
Effect of interferon-alpha and ribavirin therapy on serum GB virus C/hepatitis G virus (GBV-C/HGV) RNA levels in patients chronically infected with hepatitis C virus and GBV-C/HGV.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:2

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Chronic Disease; DNA, Viral; Drug Therapy, Combination; Female; Flaviviridae; Genetic Techniques; Hepatitis C; Hepatitis, Viral, Human; Humans; Interferon Type I; Liver; Male; Middle Aged; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Sequence Analysis, DNA; Viremia

1997
Hepatitis C and the leptin system: bound leptin levels are elevated in patients with hepatitis C and decrease during antiviral therapy.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:4

    Topics: Adult; Age Distribution; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Hepatitis C; Humans; Interferons; Leptin; Male; Middle Aged; Multivariate Analysis; Probability; Prognosis; Radioimmunoassay; Reference Values; Regression Analysis; Ribavirin; Sensitivity and Specificity; Severity of Illness Index; Sex Distribution

2001

Other Studies

92 other study(ies) available for ribavirin and Sensitivity and Specificity

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
A new choice for human rabies diagnosis: A case report of metagenomics next-generation sequencing in diagnosis of human rabies.
    Journal of infection and public health, 2022, Volume: 15, Issue:11

    Topics: Amantadine; Animals; Dogs; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Pulmonary Edema; Rabies; Ribavirin; Sensitivity and Specificity

2022
Hepatitis E virus replication in human intestinal cells.
    Gut, 2020, Volume: 69, Issue:5

    Topics: Cells, Cultured; Epithelial Cells; Genotype; Hepatitis E virus; Hepatocytes; Humans; Intestine, Small; Ribavirin; RNA, Viral; Sensitivity and Specificity; Virus Replication

2020
Hepatitis C virus core antigen: A simplified treatment monitoring tool, including for post-treatment relapse.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2017, Volume: 92

    Topics: Adult; Antiviral Agents; Drug Users; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C Antigens; Humans; Immunoassay; Male; Middle Aged; Molecular Diagnostic Techniques; Recurrence; Ribavirin; RNA, Viral; Sensitivity and Specificity; Sustained Virologic Response; Treatment Outcome; Viral Core Proteins; Viral Load; Viremia

2017
HCV antigen instead of RNA testing to diagnose acute HCV in patients treated in the Dutch Acute HCV in HIV Study.
    Journal of the International AIDS Society, 2017, 06-30, Volume: 20, Issue:1

    Topics: Adult; Hepatitis C; Hepatitis C Antigens; HIV Infections; Humans; Male; Middle Aged; Ribavirin; RNA, Viral; Sensitivity and Specificity

2017
Cost-effectiveness of daclatasvir plus asunaprevir for chronic hepatitis C genotype 1b treatment-naïve patients in China.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Adult; Antiviral Agents; Carbamates; China; Cohort Studies; Cost-Benefit Analysis; Disease Progression; Female; Genotype; Health Care Costs; Hepatitis C, Chronic; Humans; Imidazoles; Interferon-alpha; Isoquinolines; Male; Markov Chains; Middle Aged; Monte Carlo Method; Polyethylene Glycols; Probability; Pyrrolidines; Quality of Life; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Sulfonamides; Treatment Outcome; Valine

2018
Development and validation of a versatile HPLC-DAD method for simultaneous determination of the antiviral drugs daclatasvir, ledipasvir, sofosbuvir and ribavirin in presence of seven potential impurities. Application to assay of dosage forms and dissoluti
    Drug development and industrial pharmacy, 2019, Volume: 45, Issue:7

    Topics: Antiviral Agents; Benzimidazoles; Carbamates; Chromatography, High Pressure Liquid; Fluorenes; Imidazoles; Limit of Detection; Pyrrolidines; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Sofosbuvir; Solubility; Valine

2019
Development and validation of an assay for the simultaneous determination of zidovudine, abacavir, emtricitabine, lamivudine, tenofovir and ribavirin in human plasma using liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Mar-01, Volume: 919-920

    Topics: Adenine; Antiviral Agents; Chromatography, Liquid; Deoxyribonucleosides; Drug Stability; Humans; Linear Models; Organophosphonates; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tenofovir

2013
Serum proteome predicts virological response in chronic hepatitis C genotype 1b patients treated with pegylated interferon plus ribavirin.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2015, Volume: 114, Issue:7

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Logistic Models; Male; Mass Spectrometry; Middle Aged; Multivariate Analysis; Proteome; Ribavirin; Sensitivity and Specificity; Taiwan; Treatment Outcome; Viral Load

2015
Validity of aspartate aminotransferase to platelet ratio index as predictor of early viral response in patients with hepatitis C treated by interferon-based therapy.
    JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:10

    Topics: Adult; Antiviral Agents; Aspartate Aminotransferases; Chi-Square Distribution; Female; Hepatitis C; Humans; Interferons; Male; Pakistan; Platelet Count; Polymerase Chain Reaction; Predictive Value of Tests; Prospective Studies; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome

2012
Ultrasound based evaluation of hepatic steatosis and fibrosis in hepatitis C non-responders.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:8

    Topics: Adult; Aged; Biopsy; Cross-Sectional Studies; Fatty Liver; Female; Fibrosis; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Male; Middle Aged; Predictive Value of Tests; Ribavirin; Sensitivity and Specificity; Treatment Failure; Ultrasonography; Young Adult

2013
The end-of-treatment ribavirin concentration predicts hepatitis C virus relapse.
    Therapeutic drug monitoring, 2013, Volume: 35, Issue:6

    Topics: Adult; Antiviral Agents; Area Under Curve; Chromatography, Liquid; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Recurrence; Retrospective Studies; Ribavirin; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors; Treatment Outcome

2013
Development and validation of a dried blood spot assay for the quantification of ribavirin using liquid chromatography coupled to mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jan-01, Volume: 944

    Topics: Chromatography, Liquid; Dried Blood Spot Testing; Drug Stability; Humans; Linear Models; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Tandem Mass Spectrometry

2014
[Lipid kinetics during dual antiviral therapy in patients with chronic hepatitis C].
    Medicina clinica, 2015, Jun-22, Volume: 144, Issue:12

    Topics: Adult; Antiviral Agents; Chemokine CXCL10; Cholesterol; Drug Therapy, Combination; False Positive Reactions; Fatty Liver; Female; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Hypertriglyceridemia; Interferon-alpha; Interferons; Interleukins; Lipids; Lipoproteins; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Prospective Studies; Recombinant Proteins; Ribavirin; ROC Curve; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Viral Load; Viremia

2015
Measurement of intracellular ribavirin mono-, di- and triphosphate using solid phase extraction and LC-MS/MS quantification.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Jan-26, Volume: 978-979

    Topics: Chromatography, Liquid; Dried Blood Spot Testing; Erythrocytes; Humans; Intracellular Space; Leukocytes, Mononuclear; Linear Models; Nucleotides; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry

2015
Cost-effectiveness of novel regimens for the treatment of hepatitis C virus.
    Annals of internal medicine, 2015, Mar-17, Volume: 162, Issue:6

    Topics: Antiviral Agents; Benzimidazoles; Carbamates; Cost-Benefit Analysis; Disease Progression; Drug Costs; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Interferon-alpha; Patient-Specific Modeling; Pyrrolidines; Ribavirin; Sensitivity and Specificity; Simeprevir; Sofosbuvir; Sulfonamides; Uridine Monophosphate; Valine

2015
Boceprevir for Chronic Genotype 1 Hepatitis C Virus in the Current Health Care Setting in Greece: A Cost-effectiveness Analysis.
    Clinical therapeutics, 2015, Jul-01, Volume: 37, Issue:7

    Topics: Antiviral Agents; Cost-Benefit Analysis; Disease Progression; Drug Costs; Drug Therapy, Combination; Genotype; Greece; Health Care Costs; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Life Expectancy; Markov Chains; Models, Econometric; Polyethylene Glycols; Proline; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Sensitivity and Specificity

2015
Role of ITPA and IL28B variants in the management of chronic hepatitis C treatment.
    Le infezioni in medicina, 2015, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Anemia; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-beta; Interferons; Interleukins; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Genetic; Predictive Value of Tests; Pyrophosphatases; Ribavirin; Sensitivity and Specificity; Treatment Outcome

2015
The clinical significance of HCV core antigen detection during Telaprevir/Peg-Interferon/Ribavirin therapy in patients with HCV 1 genotype infection.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 69

    Topics: Aged; Antigens, Viral; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Oligopeptides; Predictive Value of Tests; Prospective Studies; Ribavirin; RNA, Viral; ROC Curve; Sensitivity and Specificity; Viral Core Proteins

2015
The Usefulness of Defining Rapid Virological Response by a Very Sensitive Assay (TMA) during Treatment of HCV Genotype 2/3 Infection.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Prospective Studies; Recurrence; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Young Adult

2015
[Association between ribavirin plasma concentration and sustained virologic response in treatment of patients with genotype 1b chronic hepatitis C with pegylated interferon-α-2b and ribavirin].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2016, Mar-20, Volume: 24, Issue:3

    Topics: Antiviral Agents; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Recurrence; Ribavirin; Sensitivity and Specificity; Sustained Virologic Response; Tandem Mass Spectrometry; Treatment Outcome; Viral Load

2016
Hemoglobin during ribavirin-based HCV therapy is closely related to circulating levels of DHEA.
    Journal of medical virology, 2017, Volume: 89, Issue:6

    Topics: Adult; Aged; Anemia; Antiviral Agents; Dehydroepiandrosterone; Female; Hemoglobins; Hepatitis C, Chronic; Humans; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Ribavirin; Sensitivity and Specificity; Young Adult

2017
Utility of enzyme-linked immunosorbent assays to test core antigen in the diagnosis and antiviral therapy management of hepatitis C virus infections.
    Journal of medical virology, 2017, Volume: 89, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Disease Management; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Hepacivirus; Hepatitis C; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Interferon-alpha; Limit of Detection; Male; Middle Aged; Predictive Value of Tests; Ribavirin; RNA, Viral; Sensitivity and Specificity; Viral Core Proteins; Viral Load; Young Adult

2017
Usefulness of a new immunoradiometric assay of HCV core antigen to predict virological response during PEG-IFN/RBV combination therapy for chronic hepatitis with high viral load of serum HCV RNA genotype 1b.
    Intervirology, 2008, Volume: 51 Suppl 1

    Topics: Antiviral Agents; Drug Therapy, Combination; Hepacivirus; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Immunoradiometric Assay; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Prognosis; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome; Viral Core Proteins; Viral Load

2008
Prediction of sustained virological response by ribavirin plasma concentration at week 4 of therapy in hepatitis C virus genotype 1 patients.
    Antiviral therapy, 2008, Volume: 13, Issue:4

    Topics: Adult; Aged; Antiviral Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Multivariate Analysis; Plasma; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; ROC Curve; Sensitivity and Specificity; Time Factors; Treatment Outcome

2008
Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C.
    Journal of hepatology, 2009, Volume: 50, Issue:1

    Topics: 2',5'-Oligoadenylate Synthetase; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Endoribonucleases; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Ribavirin; RNA, Viral; Sensitivity and Specificity

2009
Whole-body insulin sensitivity index is a highly specific predictive marker for virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients with genotype 1b and high viral load.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Glucose Tolerance Test; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Insulin Secretion; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Receptors, Tumor Necrosis Factor, Type II; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Viral Load

2010
IP-10 correlates with hepatitis C viral load, hepatic inflammation and fibrosis and predicts hepatitis C virus relapse or non-response in HIV-HCV coinfection.
    Antiviral therapy, 2008, Volume: 13, Issue:8

    Topics: Adult; Antiviral Agents; Biomarkers; Chemokine CXCL10; Dose-Response Relationship, Drug; Genotype; Hepacivirus; Hepatitis C; HIV Infections; Humans; Inflammation; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Recurrence; Ribavirin; Sensitivity and Specificity; Viral Load

2008
HPLC-MS/MS method for the intracellular determination of ribavirin monophosphate and ribavirin triphosphate in CEM ss cells.
    Journal of pharmaceutical and biomedical analysis, 2009, Jul-12, Volume: 49, Issue:5

    Topics: Antiviral Agents; Calibration; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Humans; Molecular Structure; Nucleotides; Quality Control; Reference Standards; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Impact of pegylated interferon and ribavirin on morbidity and mortality in patients with chronic hepatitis C and normal aminotransferases in France.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Child; Child, Preschool; Disease Progression; Drug Therapy, Combination; Female; France; Hepatitis C, Chronic; Humans; Infant; Infant, Newborn; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Patient Selection; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Sensitivity and Specificity; Young Adult

2009
A comprehensive hepatitis C viral kinetic model explaining cure.
    Clinical pharmacology and therapeutics, 2010, Volume: 87, Issue:6

    Topics: Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Kinetics; Models, Biological; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Viral Load

2010
Plasma/erythrocyte ribavirin x100 ratio as an indicator of sustained virological response in HCV genotype 1 patients with early virological response.
    Antiviral therapy, 2010, Volume: 15, Issue:4

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Erythrocytes; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Plasma; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Young Adult

2010
Decreased IP-10 and elevated TGFbeta1 levels are associated with viral clearance following therapy in patients with hepatitis C virus.
    Disease markers, 2010, Volume: 28, Issue:5

    Topics: Adult; Aged; Algorithms; Antiviral Agents; Area Under Curve; Chemokine CXCL10; Extracellular Matrix Proteins; Female; Hepacivirus; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Transforming Growth Factor beta; Treatment Outcome; Viral Load

2010
Quantitative determination of hepatitis C core antigen in therapy monitoring for chronic hepatitis C.
    Intervirology, 2011, Volume: 54, Issue:2

    Topics: Antigens, Viral; Antiviral Agents; Clinical Laboratory Techniques; Drug Monitoring; Hepatitis C, Chronic; Humans; Interferons; Ribavirin; RNA, Viral; Sensitivity and Specificity; Viral Core Proteins

2011
Comparable performance of TMA and Real-Time PCR in detecting minimal residual hepatitis C viraemia at the end of antiviral therapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2011, Volume: 50, Issue:3

    Topics: Antiviral Agents; Drug Monitoring; Hepatitis C, Chronic; Humans; Interferons; Molecular Diagnostic Techniques; Predictive Value of Tests; Prognosis; Ribavirin; RNA, Viral; Sensitivity and Specificity; Viremia; Virology

2011
Protein pathway activation associated with sustained virologic response in patients with chronic hepatitis C treated with pegylated interferon (PEG-IFN) and ribavirin (RBV).
    Journal of proteome research, 2011, Feb-04, Volume: 10, Issue:2

    Topics: Adult; Antiviral Agents; Area Under Curve; Female; Hepatitis C, Chronic; Humans; Intercellular Signaling Peptides and Proteins; Interferon Type I; Leukocytes, Mononuclear; Male; Middle Aged; Phosphoproteins; Polyethylene Glycols; Protein Array Analysis; Proteomics; Recombinant Proteins; Regression Analysis; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Signal Transduction; Statistics, Nonparametric

2011
Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.
    Journal of gastroenterology, 2011, Volume: 46, Issue:4

    Topics: Adult; Age Factors; Aged; Amino Acid Substitution; Antiviral Agents; Data Mining; Decision Trees; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Retrospective Studies; Ribavirin; Sensitivity and Specificity; Sex Factors; Time Factors; Viral Load; Viral Nonstructural Proteins

2011
Association of serum cytokine levels with treatment response to pegylated interferon and ribavirin therapy in genotype 1 chronic hepatitis C patients.
    The Journal of infectious diseases, 2011, Apr-15, Volume: 203, Issue:8

    Topics: Amino Acid Substitution; Antiviral Agents; Biomarkers; Cytokines; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Viral Core Proteins

2011
The use of real-time PCR to detect hepatitis C virus RNA in dried blood spots from Brazilian patients infected chronically.
    Journal of virological methods, 2012, Volume: 179, Issue:1

    Topics: Antiviral Agents; Blood; Brazil; Desiccation; Diagnostic Errors; Drug Monitoring; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Molecular Diagnostic Techniques; Polyethylene Glycols; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Specimen Handling; Virology

2012
Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response.
    Hepatology (Baltimore, Md.), 2012, Volume: 55, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Aged; Antiviral Agents; DEAD Box Protein 58; DEAD-box RNA Helicases; Drug Resistance, Viral; Female; Gene Expression; Gene Expression Profiling; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Immunity, Innate; Interferon-alpha; Interferons; Interleukins; Liver; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Predictive Value of Tests; Receptors, Immunologic; Ribavirin; ROC Curve; Sensitivity and Specificity

2012
The cost-effectiveness of birth-cohort screening for hepatitis C antibody in U.S. primary care settings.
    Annals of internal medicine, 2012, Feb-21, Volume: 156, Issue:4

    Topics: Aged; Antiviral Agents; Cohort Studies; Computer Simulation; Contraindications; Cost-Benefit Analysis; Hepatitis C Antibodies; Hepatitis C, Chronic; Humans; Interferon-alpha; Markov Chains; Mass Screening; Middle Aged; Primary Health Care; Quality-Adjusted Life Years; Ribavirin; Sensitivity and Specificity; United States

2012
Characterization of nonrapid virologic response patients infected with HCV genotype 1 who may relapse after standard therapy with peginterferon plus ribavirin.
    Journal of viral hepatitis, 2012, Volume: 19, Issue:2

    Topics: Adult; Aged; Antiviral Agents; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Models, Statistical; Polyethylene Glycols; Prognosis; Recombinant Proteins; Recurrence; Retrospective Studies; Ribavirin; Risk Assessment; Sensitivity and Specificity; Treatment Outcome; Viral Load

2012
Determination of ribavirin in human serum using liquid chromatography tandem mass spectrometry.
    Talanta, 2012, Jan-15, Volume: 88

    Topics: Calibration; Chromatography, Liquid; Drug Monitoring; Humans; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
HCV genotype-3a T cell immunity: specificity, function and impact of therapy.
    Gut, 2012, Volume: 61, Issue:11

    Topics: Antiviral Agents; Case-Control Studies; CD4-Positive T-Lymphocytes; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Immunity, Cellular; Interferon-gamma; Longitudinal Studies; Lymphocyte Activation; Male; Reference Values; Ribavirin; Sensitivity and Specificity; T-Cell Antigen Receptor Specificity

2012
25-Hydroxyvitamin D3 suppresses hepatitis C virus production.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:4

    Topics: Antiviral Agents; Calcifediol; Cell Proliferation; Cell Survival; Cells, Cultured; Cholecalciferol; Dose-Response Relationship, Drug; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Polymerase Chain Reaction; Recombinant Proteins; Ribavirin; RNA, Viral; Sampling Studies; Sensitivity and Specificity

2012
Determinants of response to triple therapy of telaprevir, peginterferon, and ribavirin in previous non-responders infected with HCV genotype 1.
    Journal of medical virology, 2012, Volume: 84, Issue:7

    Topics: Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Japan; Male; Middle Aged; Oligopeptides; Predictive Value of Tests; Ribavirin; Sensitivity and Specificity; Treatment Outcome; Virology

2012
Revisiting the predictors of a sustained virologic response in the era of direct-acting antiviral therapy for hepatitis C virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 56, Issue:1

    Topics: Adult; Antiviral Agents; Female; Hepacivirus; Hepatitis C; Host-Pathogen Interactions; Humans; Interferon-alpha; Interferons; Interleukins; Male; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Viral Load

2013
Baseline factors and early viral response (week 4) to antiviral therapy with peginterferon and ribavirin for predicting sustained virologic response in patients infected with hepatitis C virus genotype 1: a multicenter study.
    Journal of medical virology, 2013, Volume: 85, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Male; Middle Aged; Predictive Value of Tests; Prognosis; Ribavirin; RNA, Viral; Sensitivity and Specificity; Time Factors; Treatment Outcome; Viral Load; Young Adult

2013
Allelic inhibition of displacement activity: a simplified one tube allele-specific PCR for evaluation of ITPA polymorphisms.
    Journal of virological methods, 2013, Volume: 187, Issue:2

    Topics: Alleles; Anemia, Hemolytic; Antiviral Agents; Hepatitis C, Chronic; Humans; Interferons; Polymerase Chain Reaction; Polymorphism, Genetic; Pyrophosphatases; Ribavirin; Sensitivity and Specificity

2013
[Establishment of drug screening assay and pharmacodynamic evaluation method targeting influenza RNA polymerase].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:9

    Topics: Alphainfluenzavirus; Amantadine; Antiviral Agents; Drug Evaluation, Preclinical; Genes, Reporter; HEK293 Cells; Humans; Luciferases; Oseltamivir; Plasmids; Reproducibility of Results; Ribavirin; RNA-Dependent RNA Polymerase; Sensitivity and Specificity; Transfection; Zanamivir

2012
Specific, sensitive and accurate liquid chromatographic-tandem mass spectrometric method for the measurement of ribavirin in rat and monkey plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Nov-05, Volume: 779, Issue:2

    Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Macaca fascicularis; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Ribavirin; Sensitivity and Specificity

2002
Cost-effectiveness analysis of therapeutic strategies for patients with chronic hepatitis C previously not responding to interferon.
    Alimentary pharmacology & therapeutics, 2003, Mar-15, Volume: 17, Issue:6

    Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Decision Support Systems, Clinical; Drug Combinations; Hepatitis C, Chronic; Humans; Interferon-alpha; Middle Aged; Quality of Life; Ribavirin; Sensitivity and Specificity

2003
A cost-effectiveness analysis of peginterferon alfa-2b plus ribavirin for the treatment of naive patients with chronic hepatitis C.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Quality of Life; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome

2003
An heteroduplex mobility analysis assay based on capillary electrophoresis for the study of HCV quasispecies.
    Journal of virological methods, 2003, Jun-09, Volume: 110, Issue:1

    Topics: Adult; Amino Acid Sequence; Antiviral Agents; Base Sequence; Electrophoresis, Capillary; Female; Genetic Variation; Hepacivirus; Hepatitis C, Chronic; Heteroduplex Analysis; Humans; Interferons; Liver Transplantation; Male; Middle Aged; Molecular Sequence Data; Ribavirin; Sensitivity and Specificity; Sequence Analysis, DNA; Viral Proteins

2003
Comparative evaluation of the total hepatitis C virus core antigen, branched-DNA, and amplicor monitor assays in determining viremia for patients with chronic hepatitis C during interferon plus ribavirin combination therapy.
    Journal of clinical microbiology, 2003, Volume: 41, Issue:7

    Topics: Antiviral Agents; Branched DNA Signal Amplification Assay; Drug Therapy, Combination; Hepacivirus; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Immunoenzyme Techniques; Interferons; Reagent Kits, Diagnostic; Reproducibility of Results; Ribavirin; RNA, Viral; Sensitivity and Specificity; Viral Core Proteins; Viral Load; Viremia

2003
Hepatitis C virus RNA load in relapsed patients: week two of treatment is the best time to predict the complete response.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:10

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Predictive Value of Tests; Remission Induction; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Viral Load

2003
Predictive value of early HCV RNA quantitation for sustained response in nonresponders receiving daily interferon and ribavirin therapy.
    Journal of medical virology, 2004, Volume: 72, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Predictive Value of Tests; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Viral Load

2004
Comparison of the VERSANT HCV RNA qualitative assay (transcription-mediated amplification) and the COBAS AMPLICOR hepatitis C virus test, version 2.0, in patients undergoing interferon-ribavirin therapy.
    Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:4

    Topics: Antiviral Agents; Cohort Studies; Female; Follow-Up Studies; Hepacivirus; Hepatitis C; Humans; Interferons; Male; Monitoring, Physiologic; Nucleic Acid Amplification Techniques; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome

2003
Cost effectiveness of peginterferon alpha-2a plus ribavirin versus interferon alpha-2b plus ribavirin as initial therapy for treatment-naive chronic hepatitis C.
    PharmacoEconomics, 2004, Volume: 22, Issue:4

    Topics: Antiviral Agents; Cost-Benefit Analysis; Drug Therapy, Combination; Genotype; Health Care Costs; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Markov Chains; Models, Economic; Polyethylene Glycols; Quality of Life; Randomized Controlled Trials as Topic; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome

2004
Urinary nitrite/nitrate concentrations and total antioxidant capacity in patients with chronic hepatitis C in therapy with interferon and ribavirin.
    Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:6

    Topics: Adult; Antioxidants; Antiviral Agents; Biomarkers; Case-Control Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Injections, Intramuscular; Interferon alpha-2; Interferon-alpha; Linear Models; Liver Function Tests; Male; Middle Aged; Nitric Oxide; Probability; Recombinant Proteins; Ribavirin; Sampling Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome

2003
Early HCV dynamics on Peg-interferon and ribavirin in HIV/HCV co-infection: indications for the investigation of new treatment approaches.
    AIDS (London, England), 2004, Jan-02, Volume: 18, Issue:1

    Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Liver; Male; Middle Aged; Mutation; Pilot Projects; Polyethylene Glycols; Prognosis; Prospective Studies; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Viral Load; Viral Nonstructural Proteins; Virus Replication

2004
Artificial neural networks for the prediction of response to interferon plus ribavirin treatment in patients with chronic hepatitis C.
    Current pharmaceutical design, 2004, Volume: 10, Issue:17

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Databases, Factual; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Neural Networks, Computer; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Treatment Outcome

2004
Serum levels of hepatitis C virus core antigen as a marker of infection and response to therapy.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:9

    Topics: Adult; Biomarkers; Cohort Studies; Confidence Intervals; Drug Therapy, Combination; Female; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Function Tests; Male; Middle Aged; Predictive Value of Tests; Probability; Prognosis; Recombinant Proteins; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Viral Core Proteins

2004
Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.
    Pharmacogenetics and genomics, 2005, Volume: 15, Issue:2

    Topics: Alleles; Animals; Antiviral Agents; Cytoplasm; DNA; Dose-Response Relationship, Drug; Exons; Genetic Variation; Guanosine; Haplotypes; Humans; Inhibitory Concentration 50; Inosine; Kinetics; Membrane Transport Proteins; Models, Genetic; Nucleoside Transport Proteins; Nucleosides; Oocytes; Plasmids; Polymorphism, Genetic; Ribavirin; Sensitivity and Specificity; Uridine; Xenopus laevis

2005
A sensitive and specific method for the determination of total ribavirin in monkey liver by high-performance liquid chromatography with tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2005, Jun-01, Volume: 38, Issue:1

    Topics: Animals; Antiviral Agents; Calibration; Chromatography, High Pressure Liquid; Liver; Mass Spectrometry; Quality Control; Reference Standards; Reproducibility of Results; Ribavirin; Sensitivity and Specificity

2005
Studies on the variation in clinical laboratory data and safety evaluation of pharmaceuticals.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:12

    Topics: Antiviral Agents; Clinical Laboratory Information Systems; Clinical Laboratory Techniques; Clinical Trials as Topic; Data Interpretation, Statistical; Drug-Related Side Effects and Adverse Reactions; Female; Hepatitis C, Chronic; Humans; Male; Middle Aged; Patient Selection; Pharmaceutical Preparations; Reference Values; Ribavirin; Sensitivity and Specificity

2005
Sensitive and specific LC-MS/MS method for the simultaneous measurements of viramidine and ribavirin in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Feb-17, Volume: 832, Issue:1

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Reference Standards; Reference Values; Reproducibility of Results; Ribavirin; Sensitivity and Specificity

2006
Validation of liquid/liquid extraction method coupled with HPLC-UV for measurement of ribavirin plasma levels in HCV-positive patients.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, May-01, Volume: 835, Issue:1-2

    Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Monitoring; Hepatitis C, Chronic; Humans; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Ultraviolet Rays

2006
Simultaneous determination of ribavirin and ribavirin base in monkey plasma by high performance liquid chromatography with tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Feb-01, Volume: 846, Issue:1-2

    Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Haplorhini; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Tandem Mass Spectrometry

2007
A nucleotide sequence variation detection system for the core region of hepatitis C virus-1b.
    Journal of virological methods, 2007, Volume: 141, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Base Sequence; Drug Therapy, Combination; Electrophoresis; Genetic Variation; Hepacivirus; Hepatitis C; Humans; Interferons; Molecular Sequence Data; Polymerase Chain Reaction; Reproducibility of Results; Ribavirin; RNA, Viral; Sensitivity and Specificity; Serum Albumin; Viral Core Proteins; Viral Nonstructural Proteins

2007
Clinical responders to antiviral therapy of chronic HCV infection show elevated antiviral CD4+ and CD8+ T-cell responses.
    Journal of viral hepatitis, 2007, Volume: 14, Issue:5

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Black or African American; Case-Control Studies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Epitopes; Female; Flow Cytometry; Genotype; Hepacivirus; Hepatitis C, Chronic; Hispanic or Latino; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; T-Lymphocytes; Time Factors; Treatment Outcome; Viral Core Proteins; Viral Nonstructural Proteins; White People

2007
Formulations of biodegradable Nanogel carriers with 5'-triphosphates of nucleoside analogs that display a reduced cytotoxicity and enhanced drug activity.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Aug-16, Volume: 121, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Antiviral Agents; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Dideoxynucleotides; Dogs; Dose-Response Relationship, Drug; Drug Carriers; Female; Fluorescent Dyes; Formazans; Humans; Influenza A virus; Inhibitory Concentration 50; Kidney; L-Lactate Dehydrogenase; Luminescent Measurements; Membrane Potentials; Mitochondria; Nanogels; Nanotechnology; Polyethylene Glycols; Polyethyleneimine; Rhodamines; Ribavirin; Sensitivity and Specificity; Tetrazolium Salts; Thymine Nucleotides; Zidovudine

2007
Measurement of ribavirin and evaluation of its stability in human plasma by high-performance liquid chromatography with UV detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-01, Volume: 856, Issue:1-2

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2007
Qualitative application of COBAS AMPLICOR HCV test version 2.0 assays in patients with chronic hepatitis C virus infection and comparison of clinical performance with version 1.0.
    The Kaohsiung journal of medical sciences, 2007, Volume: 23, Issue:7

    Topics: Hepatitis C, Chronic; Humans; Interferons; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Sensitivity and Specificity

2007
Evaluating the cost of sustained virologic response in naïve chronic hepatitis C patients treated à la carte.
    Alimentary pharmacology & therapeutics, 2007, Sep-01, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Cost Control; Decision Trees; Drug Therapy, Combination; Economics, Pharmaceutical; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Sensitivity and Specificity

2007
The cost-effectiveness of the new protocol reflecting rapid virologic response to peginterferon alpha-2b and ribavirin for chronic hepatitis C.
    European journal of gastroenterology & hepatology, 2007, Volume: 19, Issue:9

    Topics: Antiviral Agents; Cost of Illness; Cost-Benefit Analysis; Disease Progression; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Japan; Markov Chains; Models, Econometric; Polyethylene Glycols; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; Viral Load

2007
Measurement of ribavirin plasma concentrations by high-performance liquid chromatography using a novel solid-phase extraction method in patients treated for chronic hepatitis C.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:6

    Topics: Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Monitoring; Hepatitis C, Chronic; Humans; Ribavirin; Sensitivity and Specificity; Solid Phase Extraction

2007
Assessment of hepatitis C virus-RNA clearance under combination therapy for hepatitis C virus genotype 1: performance of the transcription-mediated amplification assay.
    Journal of viral hepatitis, 2008, Volume: 15, Issue:1

    Topics: Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Nucleic Acid Amplification Techniques; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Sensitivity and Specificity; Transcription, Genetic; Treatment Outcome

2008
[Predicting sustained virological response in chronic hepatitis C patients treated with pegylated interferon and ribavirin using a novel highly sensitive Real-time detection PCR assay].
    Rinsho byori. The Japanese journal of clinical pathology, 2007, Volume: 55, Issue:11

    Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Forecasting; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Polymerase Chain Reaction; Predictive Value of Tests; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity

2007
Rapid viral response and treatment outcome in genotype 2 and 3 chronic hepatitis C: comparison between two HCV RNA quantitation methods.
    Journal of medical virology, 2008, Volume: 80, Issue:5

    Topics: Adult; Antiviral Agents; Female; Genotype; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Sensitivity and Specificity; Time Factors; Treatment Outcome; Viral Load

2008
MTT colorimetric assay system for the screening of anti-orthomyxo- and anti-paramyxoviral agents.
    Journal of virological methods, 1994, Volume: 48, Issue:2-3

    Topics: Amides; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Colorimetry; Coloring Agents; Cytidine; Dogs; HeLa Cells; Humans; Influenza A virus; Measles virus; Microbial Sensitivity Tests; Orthomyxoviridae; Pyrazoles; Respiratory Syncytial Viruses; Respirovirus; Ribavirin; Ribonucleosides; Ribose; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Vero Cells; Virus Replication

1994
Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors.
    The Journal of biological chemistry, 1995, Dec-15, Volume: 270, Issue:50

    Topics: Azaserine; Carbon Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Humans; Kinetics; Lymphocyte Activation; Models, Biological; Phytohemagglutinins; Purine Nucleosides; Purine Nucleotides; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Radioisotope Dilution Technique; Reference Values; Ribavirin; Ribonucleotides; Sensitivity and Specificity; T-Lymphocytes

1995
Comparison of three different hybridization assays in the quantitative measurement of serum hepatitis B virus DNA.
    Journal of virological methods, 1996, Volume: 62, Issue:2

    Topics: Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Monitoring; Hepatitis B; Hepatitis B virus; Humans; Nucleic Acid Hybridization; Polymerase Chain Reaction; Regression Analysis; Ribavirin; Sensitivity and Specificity; Viral Load

1996
Cost effectiveness of interferon alpha2b combined with ribavirin for the treatment of chronic hepatitis C.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:5

    Topics: Antiviral Agents; Cost-Benefit Analysis; Decision Trees; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Markov Chains; Middle Aged; Models, Statistical; Probability; Quality of Life; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Time Factors; United States

1999
Cost-effectiveness of 24 or 48 weeks of interferon alpha-2b alone or with ribavirin as initial treatment of chronic hepatitis C. International Hepatitis Interventional Therapy Group.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:6

    Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Life Expectancy; Male; Middle Aged; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Time Factors

2000
Treatment with interferon plus ribavirin in anti-HIV negative patients with congenital coagulation disorders and chronic hepatitis C.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Age Factors; Age of Onset; Alanine Transaminase; Antiviral Agents; Blood Coagulation Disorders; Child; Chronic Disease; Drug Therapy, Combination; Factor VII Deficiency; Female; Hemoglobins; Hemophilia A; Hemophilia B; Hepacivirus; Hepatitis C; HIV Antibodies; HIV Seronegativity; Humans; Interferons; Male; Middle Aged; Neutrophils; Platelet Count; Predictive Value of Tests; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Sensitivity and Specificity; Treatment Outcome; von Willebrand Diseases

2000
Compliance with therapy in patients with chronic hepatitis C: associations with psychiatric symptoms, interpersonal problems, and mode of acquisition.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:10

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Emotions; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interpersonal Relations; Male; Middle Aged; Patient Compliance; Personality; Psychometrics; Recombinant Proteins; Ribavirin; Sensitivity and Specificity

2001
Cost effectiveness of combination therapy for hepatitis C: a decision analytic model.
    Gut, 2002, Volume: 50, Issue:2

    Topics: Adult; Aged; Antiviral Agents; Cohort Studies; Cost-Benefit Analysis; Decision Support Techniques; Drug Combinations; Female; Health Resources; Health Status; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Transplantation; Male; Markov Chains; Middle Aged; Quality-Adjusted Life Years; Ribavirin; Sensitivity and Specificity

2002
24 weeks of interferon-ribavirin therapy should not routinely be given to all hepatitis C patients.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:2

    Topics: Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Prospective Studies; Ribavirin; Risk Assessment; Sensitivity and Specificity; Time Factors; Treatment Outcome; Viral Load

2002
Early detection of nonresponse to interferon plus ribavirin combination treatment of chronic hepatitis C.
    Journal of viral hepatitis, 2002, Volume: 9, Issue:3

    Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Predictive Value of Tests; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Sensitivity and Specificity; Time Factors; Treatment Outcome; Viral Load

2002
Antiviral treatment responses in patients with chronic hepatitis C virus infection evaluated by a third generation anti-hepatitis C virus assay.
    Journal of viral hepatitis, 2002, Volume: 9, Issue:4

    Topics: Adult; Aged; Antiviral Agents; Drug Combinations; Female; Hepatitis C Antibodies; Hepatitis C, Chronic; Humans; Immunoenzyme Techniques; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Reagent Kits, Diagnostic; Recombinant Proteins; Ribavirin; Sensitivity and Specificity

2002
Determination of thiazole-4-carboxamide adenine dinucleotide (TAD) levels in mononuclear cells of leukemic patients treated with tiazofurin.
    Biochemical pharmacology, 1991, Jan-15, Volume: 41, Issue:2

    Topics: Adenine Nucleotides; Antineoplastic Agents; Chromatography, High Pressure Liquid; Guanosine Triphosphate; Humans; Leukemia; Monocytes; Reproducibility of Results; Ribavirin; Sensitivity and Specificity

1991