A taste receptor type 2 member 41 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P59536]
T2R41;
Taste receptor type 2 member 59;
T2R59
Timeframe | Studies on this Protein(%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0) | 18.7374 |
1990's | 0 (0) | 18.2507 |
2000's | 0 (0) | 29.6817 |
2010's | 0 (0) | 24.3611 |
2020's | 0 (0) | 2.80 |
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
---|---|---|---|---|---|
isoproterenol | Homo sapiens (human) | EC50 | 0.0049 | 1 | 0 |
This protein enables 2 target(s):
Target | Category | Definition |
---|---|---|
G protein-coupled receptor activity | molecular function | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR] |
protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
This protein is located in 2 target(s):
Target | Category | Definition |
---|---|---|
plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
This protein is active in 1 target(s):
Target | Category | Definition |
---|---|---|
membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
This protein is involved in 1 target(s):
Target | Category | Definition |
---|---|---|
G protein-coupled receptor signaling pathway | biological process | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor] |