Compounds > tetramisole
Page last updated: 2024-09-20

tetramisole

Description

6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole : An imidazothiazole that is imidazo[2,1-b][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

tetramisole : A racemate comprising equimolar amounts of levamisole and dexamisole. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID3913
CHEMBL ID277775
CHEBI ID77278
SCHEMBL ID167819
MeSH IDM0021246

Synonyms (85)

Synonym
HMS1674C22
BRD-A46393198-003-04-2
nsc-614927
nsc614927
phenyl imidothiazole
imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-
BSPBIO_000589
PRESTWICK3_000182
BPBIO1_000115
BSPBIO_000103
LOPAC0_001194
PRESTWICK2_000545
SPBIO_002510
PRESTWICK1_000545
PRESTWICK0_000545
BPBIO1_000649
PRESTWICK3_000545
NCGC00162225-01
NCGC00162363-01
AC-11604
NCGC00015620-04
tetramizole
tetramisole
AKOS000605651
ascaverm (tn)
5036-02-2
D08576
tetramisole [veterinary] (tn)
tetramisole (inn)
STL019093
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
6649-23-6
tetramisol [inn-spanish]
unii-c8m7rfe4no
dl-tetramisole
c8m7rfe4no ,
dl-tetramisol
tetramisol
imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-
ici 50627
einecs 229-667-8
tetramisolum [inn-latin]
6-phenyl-2,3,5,6-tetrahydroimidazo(2,1-b)thiazole
imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (+-)-
einecs 225-729-3
nsc 102063
tetramisole [inn:ban]
CCG-205268
chebi:77278 ,
nsc-102063
ascaverm
levamisole dl-form
CHEMBL277775
r-8299
NCGC00015620-03
FT-0605226
(-)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole
(+/-)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole
tetramisole [who-dd]
levamisole dl-form [mi]
tetramisole [inn]
AKOS022087568
AKOS022142451
SCHEMBL167819
2,3,5,6-tetrahydro-6-phenylimidazo-[2,1-b]-thiazole
(-)-2,3,5,6-tetrahydro-6-phenylimidazol[2,1-b]thiazole
(-)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole-, (s)-
tetramisole, tetramisole hydrochloride
smr001550472
MLS006011861
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
mfcd00792481
SBI-0051161.P002
FT-0709104
DTXSID20860143
Q27146858
l-tetramisole; lepuron; levamisol; levamisole
levamisol 100 microg/ml in acetonitrile
BRD-A46393198-003-10-9
SDCCGSBI-0051161.P003
NCGC00015620-14
6-phenyl-2,3,5,6-tetrahydro imidazo [2,1-b]thiazole
SB67394
SY107591

Treatment

ExcerptReference
"All tetramisole-treated mice showed crouching behavior and were nervous and difficult to handle."( Ahmed, K; Faris, GA; Mohammad, FK; Rhayma, MS, 2006)
"All tetramisole treatments significantly reduced the number of B."( Renoux, G; Renoux, M, 1973)

Roles (2)

RoleDescription
xenobioticA xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
environmental contaminantAny minor or unwanted substance introduced into the environment that can have undesired effects.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
imidazothiazole
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (4)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
thioredoxin reductaseRattus norvegicus (Norway rat)Potency0.25120.100020.879379.4328AID588453
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency4.46680.035520.977089.1251AID504332
chromobox protein homolog 1Homo sapiens (human)Potency28.18380.006026.168889.1251AID488953
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency9.52830.060110.745337.9330AID485368
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (21)

Assay IDTitleYearJournalArticle
AID1347050Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347151Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID504836Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation2002The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
AID1347045Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347058CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347405qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347059CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347410qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library2019Cellular signalling, 08, Volume: 60A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.
AID588378qHTS for Inhibitors of ATXN expression: Validation
AID1347057CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588349qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347049Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (257)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990160 (62.26)18.7374
1990's37 (14.40)18.2507
2000's18 (7.00)29.6817
2010's32 (12.45)24.3611
2020's10 (3.89)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials7 (2.57%)5.53%
Reviews9 (3.31%)6.00%
Case Studies4 (1.47%)4.05%
Observational0 (0.00%)0.25%
Other252 (92.65%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
levamisole[no description available]medium6906-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazoleantinematodal drug;
antirheumatic drug;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
immunological adjuvant;
immunomodulator
cocaine[no description available]medium80benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
dexamisole[no description available]medium706-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazoleantidepressant
ethylene urea[no description available]medium10imidazolidinone;
ureas
aminorex[no description available]medium20benzenes
thiourea[no description available]medium20one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
palladium[no description available]medium10metal allergen;
nickel group element atom;
platinum group metal atom
dimethylglycine[no description available]medium10amino acid zwitterion;
N-methyl-amino acid;
N-methylglycines		Daphnia magna metabolite;
human metabolite;
mouse metabolite
sarcosine[no description available]medium10N-alkylglycine zwitterion;
N-alkylglycine;
N-methyl-amino acid;
N-methylglycines		Escherichia coli metabolite;
glycine receptor agonist;
glycine transporter 1 inhibitor;
human metabolite;
mouse metabolite
imidazole[no description available]medium20imidazole
phenacetin[no description available]medium20acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug
glaucine[no description available]medium10aporphine alkaloid;
organic heterotetracyclic compound;
polyether;
tertiary amino compound		antibacterial agent;
antineoplastic agent;
antitussive;
muscle relaxant;
NF-kappaB inhibitor;
plant metabolite;
platelet aggregation inhibitor;
rat metabolite
lidocaine[no description available]medium20benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
codeine[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic
caffeine[no description available]medium20purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
ketamine[no description available]medium10cyclohexanones;
monochlorobenzenes;
secondary amino compound		analgesic;
environmental contaminant;
intravenous anaesthetic;
neurotoxin;
NMDA receptor antagonist;
xenobiotic
atropine[no description available]medium20
hydroxyzine[no description available]medium10hydroxyether;
monochlorobenzenes;
N-alkylpiperazine		anticoronaviral agent;
antipruritic drug;
anxiolytic drug;
dermatologic drug;
H1-receptor antagonist
benzotetramisole[no description available]medium120
oxazoles[no description available]medium101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
thiazolidines[no description available]medium10thiazolidine
alkenes[no description available]medium10
diphenylacetic acid[no description available]medium10monocarboxylic acidxenobiotic metabolite
diethylcarbamazine[no description available]medium60N-carbamoylpiperazine;
N-methylpiperazine
enilconazole[no description available]medium10dichlorobenzene;
ether;
imidazoles
indoprofen[no description available]medium10gamma-lactam;
isoindoles;
monocarboxylic acid		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
carprofen[no description available]medium10carbazoles;
organochlorine compound		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug;
photosensitizing agent
ibuprofen[no description available]medium10monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
ifosfamide[no description available]medium10ifosfamidesalkylating agent;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
xenobiotic
naproxen[no description available]medium20methoxynaphthalene;
monocarboxylic acid		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
omeprazole[no description available]medium10aromatic ether;
benzimidazoles;
pyridines;
sulfoxide
flurbiprofen[no description available]medium10fluorobiphenyl;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
chloramphenicol[no description available]medium10C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
praziquantel[no description available]medium40isoquinolines
ofloxacin[no description available]medium103-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline
fenbendazole[no description available]medium32aryl sulfide;
benzimidazoles;
carbamate ester		antinematodal drug
dextrothyroxine[no description available]medium51
beta-lactams[no description available]medium10beta-lactam antibiotic allergen;
beta-lactam
beta-glycerophosphoric acid[no description available]medium40glycerol monophosphateEscherichia coli metabolite;
plant metabolite
alizarin[no description available]medium10dihydroxyanthraquinonechromophore;
dye;
plant metabolite
oxazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anxiolytic drug;
environmental contaminant;
xenobiotic
cellulose[no description available]medium10glycoside
pindolol[no description available]medium10indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
carbamates[no description available]medium80amino-acid anion
glyburide[no description available]medium20monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
albendazole[no description available]medium30aryl sulfide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		anthelminthic drug;
microtubule-destabilising agent;
tubulin modulator
adenosine monophosphate[no description available]medium50adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
proline[no description available]medium10amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
4-bromotetramisole[no description available]medium380
ubiquinone[no description available]medium10
thymic factor, circulating[no description available]medium10
myelin basic protein[no description available]medium10
ouabain[no description available]medium8011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
4-nitrophenylphosphate[no description available]medium40aryl phosphatemouse metabolite
adenosine 5'-methylenediphosphate[no description available]medium10nucleoside diphosphate analogue
adenosine diphosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
nitrophenols[no description available]medium60
cysteine[no description available]medium10cysteiniumfundamental metabolite
ascorbic acid[no description available]medium20ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
edetic acid[no description available]medium30ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
rafoxanide[no description available]medium50
niclosamide[no description available]medium40benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
mebendazole[no description available]medium81aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
penicillamine[no description available]medium10non-proteinogenic alpha-amino acid;
penicillamine		antirheumatic drug;
chelator;
copper chelator;
drug allergen
arsenamide[no description available]medium10
dithiazanine[no description available]medium20benzothiazoles;
benzothiazolium ion		anthelminthic drug;
fluorochrome
phenylalanine[no description available]medium60amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenylalanine amide[no description available]medium20amino acid amide;
phenylalanine derivative
histamine[no description available]medium10aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
thiazoles[no description available]medium601,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
glycogen[no description available]medium10
thiabendazole[no description available]medium1611,3-thiazoles;
benzimidazole fungicide;
benzimidazoles		antifungal agrochemical;
antinematodal drug
reserpine[no description available]medium20alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
amphetamine[no description available]medium10primary amine
phospho-l-arginine[no description available]medium10L-arginine derivative;
non-proteinogenic L-alpha-amino acid;
phosphagen;
phosphoamino acid		animal metabolite
arginine[no description available]medium10arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
tartaric acid[no description available]medium20tartaric acidEscherichia coli metabolite
phosphorus radioisotopes[no description available]medium20
oxibendazole[no description available]medium11benzimidazoles;
carbamate ester
oxfendazole[no description available]medium11benzimidazoles;
carbamate ester;
sulfoxide		antinematodal drug
parbendazole[no description available]medium11benzimidazoles;
carbamate ester
cambendazole[no description available]medium11
trichlorfon[no description available]medium41organic phosphonate;
organochlorine compound;
phosphonic ester		agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
pyrantel[no description available]medium921,4,5,6-tetrahydropyrimidines;
carboxamidine;
thiophenes		antinematodal drug
homoarginine[no description available]medium10homoarginine;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid		biomarker;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
human metabolite;
rat metabolite;
xenobiotic metabolite
zinc chloride[no description available]medium10inorganic chloride;
zinc molecular entity		astringent;
disinfectant;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
Lewis acid
molybdenum[no description available]medium10chromium group element atommicronutrient
molybdate ion[no description available]medium10divalent inorganic anion;
molybdenum oxoanion		Escherichia coli metabolite
sodium fluoride[no description available]medium50fluoride saltmutagen
phosphotyrosine[no description available]medium10L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid;
O(4)-phosphotyrosine		Escherichia coli metabolite;
immunogen
iodine[no description available]medium10halide anion;
monoatomic iodine		human metabolite
chlorine[no description available]medium40halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
vanadates[no description available]medium50trivalent inorganic anion;
vanadium oxoanion		EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
colforsin[no description available]medium40acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
calcimycin[no description available]medium10benzoxazole
h 89[no description available]medium10N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
thiophosphoric acid[no description available]medium20phosphorothioic acid
phosphorylethanolamine[no description available]medium10phosphoethanolamine;
primary amino compound		algal metabolite;
human metabolite;
mouse metabolite
egtazic acid[no description available]medium10diether;
tertiary amino compound;
tetracarboxylic acid		chelator
acid phosphatase[no description available]medium10
p-chloromercuribenzoic acid[no description available]medium10chlorine molecular entity;
mercuribenzoic acid
1-methyl-3-isobutylxanthine[no description available]medium203-isobutyl-1-methylxanthine
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
suramin[no description available]medium20naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
fructose 2,6-diphosphate[no description available]medium10D-fructofuranose 2,6-bisphosphatehuman metabolite;
mouse metabolite
guanosine monophosphate[no description available]medium10guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite
calcium pyrophosphate[no description available]medium10calcium phosphate
dantrolene[no description available]medium10hydrazone;
imidazolidine-2,4-dione		muscle relaxant;
neuroprotective agent;
ryanodine receptor antagonist
gallic acid[no description available]medium10trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate[no description available]medium10trihydroxybenzoic acid
closantel[no description available]medium20aromatic amide;
monocarboxylic acid amide;
monochlorobenzenes;
nitrile;
organoiodine compound;
phenols
mastoparan[no description available]medium10mastoparans;
peptidyl amide		antimicrobial agent
tetradecanoylphorbol acetate[no description available]medium10acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
sq-23377[no description available]medium10cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite
tyrosine[no description available]medium20amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
genistein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
arsenic[no description available]medium10metalloid atom;
pnictogen		micronutrient
oxophenylarsine[no description available]medium10arsine oxidesantineoplastic agent;
apoptosis inducer;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
angiotensin ii[no description available]medium10amino acid zwitterion;
angiotensin II		human metabolite
staurosporine[no description available]medium10ammonium ion derivative
arachidonic acid[no description available]medium10icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
ucn 1028 c[no description available]medium10
avermectin[no description available]medium20
hydroxyproline[no description available]medium104-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
fluorides[no description available]medium20halide anion;
monoatomic fluorine
urethane[no description available]medium10carbamate esterfungal metabolite;
mutagen
tyramine[no description available]medium20monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
potassium chloride[no description available]medium10inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
chiniofon[no description available]medium10
metronidazole[no description available]medium20C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
paromomycin[no description available]medium20amino cyclitol glycoside;
aminoglycoside antibiotic		anthelminthic drug;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug
quinacrine[no description available]medium20acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
furazolidone[no description available]medium10nitrofuran antibiotic;
oxazolidines		antibacterial drug;
antiinfective agent;
antitrichomonal drug;
EC 1.4.3.4 (monoamine oxidase) inhibitor
emetine[no description available]medium10isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
hexobarbital[no description available]medium10barbiturates
phenoxybenzamine[no description available]medium10aromatic amine
vincamine[no description available]medium10alkaloid ester;
hemiaminal;
methyl ester;
organic heteropentacyclic compound;
vinca alkaloid		antihypertensive agent;
metabolite;
vasodilator agent
bithionol[no description available]medium10aryl sulfide;
bridged diphenyl antifungal drug;
bridged diphenyl fungicide;
dichlorobenzene;
organochlorine pesticide;
polyphenol		antifungal agrochemical;
antiplatyhelmintic drug
morantel[no description available]medium40
niridazole[no description available]medium201,3-thiazoles;
C-nitro compound
thioguanine anhydrous[no description available]medium202-aminopurinesanticoronaviral agent;
antimetabolite;
antineoplastic agent
selenium[no description available]medium10chalcogen;
nonmetal atom		micronutrient
c.i. 42510[no description available]medium10
santonin[no description available]medium10botanical anti-fungal agent;
santonin		plant metabolite
antimony[no description available]medium10metalloid atom;
pnictogen
tetrachloroethylene[no description available]medium10chlorocarbon;
chloroethenes		nephrotoxic agent
nitroxinil[no description available]medium10
oxyclozanide[no description available]medium40
arecoline[no description available]medium10enoate ester;
methyl ester;
pyridine alkaloid;
tetrahydropyridine		metabolite;
muscarinic agonist
dichlorvos[no description available]medium30alkenyl phosphate;
dialkyl phosphate;
organochlorine acaricide;
organophosphate insecticide		anthelminthic drug;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
beryllium[no description available]medium10alkaline earth metal atom;
elemental beryllium;
metal allergen		adjuvant;
carcinogenic agent;
epitope
pyrantel pamoate[no description available]medium11organic molecular entity
zeolites[no description available]medium10
nickel[no description available]medium10metal allergen;
nickel group element atom		epitope;
micronutrient
manganese[no description available]medium10elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
adenylyl imidodiphosphate[no description available]medium10adenosine 5'-phosphate
alpha,beta-methyleneadenosine 5'-triphosphate[no description available]medium10nucleoside triphosphate analogue
5'-adenylyl (beta,gamma-methylene)diphosphonate[no description available]medium10nucleoside triphosphate analogue
sepharose[no description available]medium10
pyrophosphate[no description available]medium20diphosphate ion
trichloroacetic acid[no description available]medium10monocarboxylic acid;
organochlorine compound		carcinogenic agent;
metabolite;
mouse metabolite
dithionitrobenzoic acid[no description available]medium10nitrobenzoic acid;
organic disulfide		indicator
diphenhydramine[no description available]medium10ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
morphine[no description available]medium20morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
hexamethonium[no description available]medium10quaternary ammonium salt
pimagedine[no description available]medium10guanidines;
one-carbon compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor
guanidine[no description available]medium10carboxamidine;
guanidines;
one-carbon compound
theophylline[no description available]medium10dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
cimetidine[no description available]medium10aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
thiophanate[no description available]medium10benzimidazole precursor fungicide;
carbamate ester;
carbamate fungicide;
thioureas		antifungal drug
bephenium hydroxynaphthoate[no description available]medium10
bunamidine[no description available]medium10
piperazine[no description available]medium10azacycloalkane;
piperazines;
saturated organic heteromonocyclic parent		anthelminthic drug
diethanolamine[no description available]medium10ethanolamineshuman xenobiotic metabolite
reactive yellow 13[no description available]medium10
tin[no description available]medium10carbon group element atom;
elemental tin;
metal atom		micronutrient
phosphorus[no description available]medium10monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
chloroquine[no description available]medium10aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
sulfamethazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic
carmustine[no description available]medium10N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
cadmium[no description available]medium10cadmium molecular entity;
zinc group element atom
cyclopentane[no description available]medium10cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
phenyl acetate[no description available]medium10benzenes;
phenyl acetates
fomesafen[no description available]medium10aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
trolamine salicylate[no description available]medium10
foxes[no description available]medium10
octane[no description available]low00alkanexenobiotic
2-nitropropane[no description available]low00secondary nitroalkanecarcinogenic agent;
hepatotoxic agent;
polar aprotic solvent;
xenobiotic
bupropion[no description available]low00aromatic ketone;
monochlorobenzenes;
secondary amino compound		antidepressant;
environmental contaminant;
xenobiotic
dibenzofuran[no description available]low00dibenzofurans;
mancude organic heterotricyclic parent;
polycyclic heteroarene		xenobiotic
1-(3-chlorophenyl)piperazine[no description available]low00monochlorobenzenes;
N-arylpiperazine		drug metabolite;
environmental contaminant;
serotonergic agonist;
xenobiotic
acetaminophen[no description available]low00acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
acetochlor[no description available]low00aromatic amide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
alachlor[no description available]low00aromatic amide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
albuterol[no description available]low00phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
alprazolam[no description available]low00organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
diatrizoic acid[no description available]low00acetamides;
benzoic acids;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
dan 2163[no description available]low00aromatic amide;
aromatic amine;
benzamides;
pyrrolidines;
sulfone		environmental contaminant;
second generation antipsychotic;
xenobiotic
amitriptyline[no description available]low00carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
antazoline[no description available]low00aromatic amine;
imidazolines;
tertiary amino compound		cholinergic antagonist;
H1-receptor antagonist;
xenobiotic
antipyrine[no description available]low00pyrazoloneantipyretic;
cyclooxygenase 3 inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
atenolol[no description available]low00ethanolamines;
monocarboxylic acid amide;
propanolamine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic
atrazine[no description available]low00chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
bentazone[no description available]low00benzothiadiazineenvironmental contaminant;
herbicide;
xenobiotic
candesartan[no description available]low00benzimidazolecarboxylic acid;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
carbamazepine[no description available]low00dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
cetirizine[no description available]low00ether;
monocarboxylic acid;
monochlorobenzenes;
piperazines		anti-allergic agent;
environmental contaminant;
H1-receptor antagonist;
xenobiotic
chloral hydrate[no description available]low00aldehyde hydrate;
ethanediol;
organochlorine compound		general anaesthetic;
mouse metabolite;
sedative;
xenobiotic
chlorpyrifos[no description available]low00chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
ciprofloxacin[no description available]low00aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
clotrimazole[no description available]low00conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
diazepam[no description available]low001,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
diazinon[no description available]low00organic thiophosphate;
pyrimidines		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
nematicide;
xenobiotic
dicamba[no description available]low00dichlorobenzene;
methoxybenzoic acid		agrochemical;
environmental contaminant;
herbicide;
synthetic auxin;
xenobiotic
dichlobanil[no description available]low00dichlorobenzene;
nitrile		agrochemical;
cellulose synthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
diclofenac[no description available]low00amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
dimethoate[no description available]low00monocarboxylic acid amide;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
diuron[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene		environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic
fenofibrate[no description available]low00aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
fluconazole[no description available]low00conazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug		environmental contaminant;
P450 inhibitor;
xenobiotic
fluorouracil[no description available]low00nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
furosemide[no description available]low00chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
gabapentin[no description available]low00gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic
hydrochlorothiazide[no description available]low00benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
indomethacin[no description available]low00aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
iohexol[no description available]low00benzenedicarboxamide;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
iomeprol[no description available]low00benzenedicarboxamide;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
iopromide[no description available]low00dicarboxylic acid diamide;
organoiodine compound		environmental contaminant;
nephrotoxic agent;
radioopaque medium;
xenobiotic
avapro[no description available]low00azaspiro compound;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
ketoprofen[no description available]low00benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
lamotrigine[no description available]low001,2,4-triazines;
dichlorobenzene;
primary arylamine		anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic
mefenamic acid[no description available]low00aminobenzoic acid;
secondary amino compound		analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
metformin[no description available]low00guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
methomyl[no description available]low00aliphatic sulfide;
carbamate ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
nematicide;
xenobiotic
metoclopramide[no description available]low00benzamides;
monochlorobenzenes;
substituted aniline;
tertiary amino compound		antiemetic;
dopaminergic antagonist;
environmental contaminant;
gastrointestinal drug;
xenobiotic
metoprolol[no description available]low00aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic
moclobemide[no description available]low00benzamides;
monochlorobenzenes;
morpholines		antidepressant;
environmental contaminant;
xenobiotic
deet[no description available]low00benzamides;
monocarboxylic acid amide		environmental contaminant;
insect repellent;
xenobiotic
1-(3-trifluoromethylphenyl)piperazine[no description available]low00(trifluoromethyl)benzenes;
N-arylpiperazine		environmental contaminant;
psychotropic drug;
serotonergic agonist;
xenobiotic
nitroglycerin[no description available]low00nitroglycerolexplosive;
muscle relaxant;
nitric oxide donor;
prodrug;
tocolytic agent;
vasodilator agent;
xenobiotic
norfloxacin[no description available]low00fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug;
DNA synthesis inhibitor;
environmental contaminant;
xenobiotic
oxybenzone[no description available]low00hydroxybenzophenone;
monomethoxybenzene		dermatologic drug;
environmental contaminant;
protective agent;
ultraviolet filter;
xenobiotic
pantoprazole[no description available]low00aromatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic
pentamidine[no description available]low00aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic
pioglitazone[no description available]low00aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic
primidone[no description available]low00pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
prometone[no description available]low00diamino-1,3,5-triazine;
methoxy-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
prometryne[no description available]low00diamino-1,3,5-triazine;
methylthio-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
propachlor[no description available]low00anilide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
propazine[no description available]low00chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
propranolol[no description available]low00naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
saccharin[no description available]low001,2-benzisothiazole;
N-sulfonylcarboxamide		environmental contaminant;
sweetening agent;
xenobiotic
sulfadiazine[no description available]low00pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
simazine[no description available]low00chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
sotalol[no description available]low00ethanolamines;
secondary alcohol;
secondary amino compound;
sulfonamide		anti-arrhythmia drug;
beta-adrenergic antagonist;
environmental contaminant;
xenobiotic
sulfadimethoxine[no description available]low00aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfamethoxazole[no description available]low00isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
sulfapyridine[no description available]low00pyridines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
dermatologic drug;
drug allergen;
environmental contaminant;
xenobiotic
sulfathiazole[no description available]low001,3-thiazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
triclosan[no description available]low00aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols		antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic
trifluralin[no description available]low00(trifluoromethyl)benzenes;
C-nitro compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
trimethoprim[no description available]low00aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
trimipramine[no description available]low00dibenzoazepine;
tertiary amino compound		antidepressant;
environmental contaminant;
xenobiotic
venlafaxine[no description available]low00cyclohexanols;
monomethoxybenzene;
tertiary alcohol;
tertiary amino compound		adrenergic uptake inhibitor;
analgesic;
antidepressant;
dopamine uptake inhibitor;
environmental contaminant;
serotonin uptake inhibitor;
xenobiotic
prednisolone[no description available]low0011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic
spironolactone[no description available]low003-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
aminopyrine[no description available]low00pyrazolone;
tertiary amino compound		antipyretic;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
barbituric acid[no description available]low00barbituratesallergen;
xenobiotic
bisphenol a[no description available]low00bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
methylprednisolone[no description available]low006-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic
pseudoephedrine[no description available]low00phenylethanolamines;
secondary alcohol;
secondary amino compound		anti-asthmatic drug;
bronchodilator agent;
central nervous system drug;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
2-methyl-4-chlorophenoxy gamma-butyric acid[no description available]low00aromatic ether;
monocarboxylic acid;
monochlorobenzenes		environmental contaminant;
phenoxy herbicide;
xenobiotic
benzotriazole[no description available]low00benzotriazolesenvironmental contaminant;
xenobiotic
benzothiazole[no description available]low00benzothiazolesenvironmental contaminant;
plant metabolite;
xenobiotic
3,4-dichloroaniline[no description available]low00dichloroanilineepitope;
xenobiotic
acetophenone[no description available]low00acetophenonesanimal metabolite;
photosensitizing agent;
xenobiotic
phenylhydrazine[no description available]low00phenylhydrazinesxenobiotic
triclocarban[no description available]low00dichlorobenzene;
monochlorobenzenes;
phenylureas		antimicrobial agent;
antiseptic drug;
disinfectant;
environmental contaminant;
xenobiotic
fenuron[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylureaagrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
xenobiotic
cyanuric acid[no description available]low001,3,5-triazinanes;
1,3,5-triazines;
heteroaryl hydroxy compound		xenobiotic
diglyme[no description available]low00polyetherenvironmental contaminant;
solvent;
xenobiotic
propylene[no description available]low00alkene;
gas molecular entity		refrigerant;
xenobiotic
2-naphthalenesulfonic acid[no description available]low00naphthalenesulfonic acidenvironmental contaminant;
xenobiotic
4-sulfanilic acid[no description available]low00aminobenzenesulfonic acidallergen;
environmental contaminant;
xenobiotic metabolite;
xenobiotic
5-tolyltriazole[no description available]low00benzotriazolesenvironmental contaminant;
xenobiotic
monuron[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylurea;
monochlorobenzenes		environmental contaminant;
herbicide;
xenobiotic
ephedrine[no description available]low00phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
linuron[no description available]low00dichlorobenzene;
phenylureas		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
perfluorooctanoic acid[no description available]low00fluoroalkanoic acidcarcinogenic agent;
endocrine disruptor;
environmental contaminant;
surfactant;
xenobiotic
perfluorodecanoic acid[no description available]low00fluoroalkanoic acidenvironmental contaminant;
xenobiotic
perfluorobutyric acid[no description available]low00fluoroalkanoic acidchromatographic reagent;
environmental contaminant;
xenobiotic
triphenylmethane[no description available]low00triarylmethaneenvironmental contaminant;
xenobiotic
methamphetamine[no description available]low00amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
3-methylquinoline[no description available]low00methylquinolinexenobiotic
terbutryne[no description available]low00diamino-1,3,5-triazine;
methylthio-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
ethambutol[no description available]low00ethanolamines;
ethylenediamine derivative		antitubercular agent;
environmental contaminant;
xenobiotic
metformin hydrochloride[no description available]low00hydrochlorideenvironmental contaminant;
hypoglycemic agent;
xenobiotic
ioxynil[no description available]low00iodophenol;
nitrile		environmental contaminant;
herbicide;
xenobiotic
bromoxynil[no description available]low00dibromobenzene;
hydroxynitrile;
phenols		environmental contaminant;
herbicide;
xenobiotic
pyrazon[no description available]low00benzenes;
organochlorine compound;
primary amino compound;
pyridazinone		environmental contaminant;
herbicide;
xenobiotic
methiocarb[no description available]low00aryl sulfide;
carbamate ester;
methyl sulfide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
molluscicide;
xenobiotic
lenacil[no description available]low00cyclopentapyrimidineagrochemical;
environmental contaminant;
herbicide;
xenobiotic
fluometuron[no description available]low00(trifluoromethyl)benzenes;
3-(3,4-substituted-phenyl)-1,1-dimethylurea		agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
xenobiotic
1,2-benzisothiazoline-3-one[no description available]low00organic heterobicyclic compound;
organonitrogen heterocyclic compound		disinfectant;
drug allergen;
environmental contaminant;
platelet aggregation inhibitor;
sensitiser;
xenobiotic
asulam[no description available]low00carbamate ester;
primary amino compound;
substituted aniline;
sulfonamide		agrochemical;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
chlorpyrifos-methyl[no description available]low00chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
terbutylazine[no description available]low00chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
1-indanol[no description available]low00aromatic alcohol;
indanes;
secondary alcohol		xenobiotic
desmedipham[no description available]low00carbamate esteragrochemical;
environmental contaminant;
herbicide;
xenobiotic
phenmedipham[no description available]low00carbamate esterenvironmental contaminant;
herbicide;
xenobiotic
chlortoluron[no description available]low00monochlorobenzenes;
phenylureas		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
methoxuron[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylurea;
monochlorobenzenes;
monomethoxybenzene		agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
plant growth regulator;
xenobiotic
neohesperidin dihydrochalcone[no description available]low00dihydrochalcones;
disaccharide derivative;
neohesperidoside		environmental contaminant;
plant metabolite;
sweetening agent;
xenobiotic
metribuzin[no description available]low001,2,4-triazines;
cyclic ketone;
organic sulfide		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
cyanazine[no description available]low001,3,5-triazinylamino nitrile;
chloro-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
pirimicarb[no description available]low00aminopyrimidine;
carbamate ester;
tertiary amino compound		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
butachlor[no description available]low00aromatic amide;
organochlorine compound;
tertiary carboxamide		environmental contaminant;
herbicide;
xenobiotic
propamocarb[no description available]low00carbamate ester;
carbamate fungicide;
tertiary amino compound		antifungal agrochemical;
environmental contaminant;
xenobiotic
5-chloro-2-methyl-4-isothiazolin-3-one[no description available]low001,2-thiazoles;
organochlorine compound		antimicrobial agent;
environmental contaminant;
xenobiotic
2-n-octyl-4-isothiazolin-3-one[no description available]low001,2-thiazolesantibacterial agent;
antifungal agrochemical;
environmental contaminant;
xenobiotic
ioxitalamic acid[no description available]low00acetamides;
benzoic acids;
dicarboxylic acid monoamide;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
amitraz[no description available]low00formamidines;
tertiary amino compound		acaricide;
environmental contaminant;
insecticide;
xenobiotic
acetosulfame[no description available]low00organic heteromonocyclic compound;
organonitrogen heterocyclic compound;
oxacycle;
sulfamate ester		environmental contaminant;
sweetening agent;
xenobiotic
isoproturon[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylureaagrochemical;
environmental contaminant;
herbicide;
xenobiotic
metamitron[no description available]low001,2,4-triazinesenvironmental contaminant;
herbicide;
xenobiotic
bezafibrate[no description available]low00aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
triclopyr[no description available]low00aromatic ether;
chloropyridine;
monocarboxylic acid		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
propiconazole[no description available]low00conazole fungicide;
cyclic ketal;
dichlorobenzene;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
metazachlor[no description available]low00aromatic amide;
organochlorine compound;
pyrazoles		environmental contaminant;
herbicide;
xenobiotic
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid[no description available]low00aminopyridine;
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		environmental contaminant;
herbicide;
xenobiotic
fenoxycarb[no description available]low00aromatic ether;
carbamate ester		environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic
metsulfuron methyl[no description available]low001,3,5-triazines;
benzoate ester;
N-sulfonylurea		environmental contaminant;
herbicide;
xenobiotic
pravastatin[no description available]low003-hydroxy carboxylic acid;
carbobicyclic compound;
carboxylic ester;
hydroxy monocarboxylic acid;
secondary alcohol;
statin (semi-synthetic)		anticholesteremic drug;
environmental contaminant;
metabolite;
xenobiotic
clomazone[no description available]low00isoxazolidinone;
monochlorobenzenes		agrochemical;
carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
atomoxetine[no description available]low00aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
aromasil[no description available]low0017-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor;
environmental contaminant;
xenobiotic
gemcitabine[no description available]low00organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic
atorvastatin[no description available]low00aromatic amide;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrroles;
statin (synthetic)		environmental contaminant;
xenobiotic
valsartan[no description available]low00biphenylyltetrazole;
monocarboxylic acid amide;
monocarboxylic acid		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
prosulfocarb[no description available]low00benzenes;
monothiocarbamic ester		environmental contaminant;
herbicide;
xenobiotic
3-iodo-2-propynylbutylcarbamate[no description available]low00acetylenic compound;
carbamate ester;
carbamate fungicide;
organoiodine compound		antifungal agrochemical;
environmental contaminant;
xenobiotic
oseltamivir[no description available]low00acetamides;
amino acid ester;
cyclohexenecarboxylate ester;
primary amino compound		antiviral drug;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
environmental contaminant;
prodrug;
xenobiotic
iopamidol[no description available]low00benzenedicarboxamide;
organoiodine compound;
pentol		environmental contaminant;
radioopaque medium;
xenobiotic
iobitridol[no description available]low00benzenedicarboxamide;
hexol;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
telmisartan[no description available]low00benzimidazoles;
biphenyls;
carboxybiphenyl		angiotensin receptor antagonist;
antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
environmental contaminant;
xenobiotic
perfluorohexanoic acid[no description available]low00fluoroalkanoic acidenvironmental contaminant;
xenobiotic
perfluoro-n-heptanoic acid[no description available]low00fluoroalkanoic acidenvironmental contaminant;
xenobiotic
perfluoro-n-nonanoic acid[no description available]low00fluoroalkanoic acidpersistent organic pollutant;
surfactant;
xenobiotic
acamprosate[no description available]low00acetamides;
organosulfonic acid		environmental contaminant;
neurotransmitter agent;
xenobiotic
trichlorosucrose[no description available]low00disaccharide derivative;
organochlorine compound		environmental contaminant;
sweetening agent;
xenobiotic
nicosulfuron[no description available]low00N-sulfonylurea;
pyridines;
pyrimidines		environmental contaminant;
herbicide;
xenobiotic
prochloraz[no description available]low00amide fungicide;
aromatic ether;
conazole fungicide;
imidazole fungicide;
imidazoles;
trichlorobenzene;
ureas		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
thifensulfuron methyl[no description available]low001,3,5-triazines;
methyl ester;
N-sulfonylurea;
thiophenes		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
flusilazole[no description available]low00conazole fungicide;
monofluorobenzenes;
organosilicon compound;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
perfluoropentanoic acid[no description available]low00fluoroalkanoic acidenvironmental contaminant;
xenobiotic
1-benzylpiperazine[no description available]low00N-alkylpiperazineenvironmental contaminant;
psychotropic drug;
serotonergic agonist;
xenobiotic
perfluoroundecanoic acid[no description available]low00fluoroalkanoic acidenvironmental contaminant;
xenobiotic
sulfluramid[no description available]low00sulfonamideacaricide;
environmental contaminant;
insecticide;
xenobiotic
clarithromycin[no description available]low00macrolide antibioticantibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic
spiroxamine[no description available]low00dioxolane;
spiroketal;
tertiary amino compound		antifungal agrochemical;
environmental contaminant;
sterol biosynthesis inhibitor;
xenobiotic
difenoconazole[no description available]low00aromatic ether;
conazole fungicide;
cyclic ketal;
dioxolane;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
dimethomorph[no description available]low00mixture;
morpholine fungicide		antifungal agrochemical;
environmental contaminant;
xenobiotic
cyprodinil[no description available]low00aminopyrimidine;
anilinopyrimidine fungicide;
cyclopropanes;
secondary amino compound		antifungal agrochemical;
aryl hydrocarbon receptor agonist;
environmental contaminant;
xenobiotic
imidacloprid[no description available]low00imidacloprid;
imidazolidines;
monochloropyridine		environmental contaminant;
genotoxin;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic
foe 5043[no description available]low00aromatic amide;
monofluorobenzenes;
thiadiazoles		environmental contaminant;
herbicide;
xenobiotic
nicotine[no description available]low003-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
irgarol 1051[no description available]low00aryl sulfide;
cyclopropanes;
diamino-1,3,5-triazine		antifouling biocide;
environmental contaminant;
xenobiotic
pyrimethanil[no description available]low00aminopyrimidine;
anilinopyrimidine fungicide;
secondary amino compound		antifungal agrochemical;
aryl hydrocarbon receptor agonist;
environmental contaminant;
xenobiotic
kathon 930[no description available]low001,2-thiazoles;
organochlorine compound		environmental contaminant;
fungicide;
xenobiotic
fluazinam[no description available]low00(trifluoromethyl)benzenes;
aminopyridine;
C-nitro compound;
chloropyridine;
monochlorobenzenes;
secondary amino compound		allergen;
antifungal agrochemical;
apoptosis inducer;
environmental contaminant;
xenobiotic
teflubenzuron[no description available]low00dichlorobenzene;
difluorobenzene;
N-acylurea		environmental contaminant;
insecticide;
xenobiotic
diflufenican[no description available]low00(trifluoromethyl)benzenes;
aromatic ether;
pyridinecarboxamide		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
sulcotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclohexanones;
sulfone		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
tebufenozide[no description available]low00carbohydrazideecdysone agonist;
environmental contaminant;
xenobiotic
dpx e9636[no description available]low00aromatic ether;
N-sulfonylurea;
pyridines;
pyrimidines;
sulfone		environmental contaminant;
herbicide;
xenobiotic
arsenocholine[no description available]low00arsonium ion;
organoarsenic compound		human urinary metabolite;
marine metabolite;
xenobiotic
methoxyfenozide[no description available]low00carbohydrazide;
monomethoxybenzene		environmental contaminant;
insecticide;
xenobiotic
thiamethoxam[no description available]low001,3-thiazoles;
2-nitroguanidine derivative;
organochlorine compound;
oxadiazane		antifeedant;
carcinogenic agent;
environmental contaminant;
neonicotinoid insectide;
xenobiotic
thiacloprid[no description available]low00monochloropyridine;
nitrile;
thiazolidines		environmental contaminant;
neonicotinoid insectide;
xenobiotic
aspartame[no description available]low00carboxylic acid;
dipeptide zwitterion;
dipeptide;
methyl ester		apoptosis inhibitor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
environmental contaminant;
micronutrient;
nutraceutical;
sweetening agent;
xenobiotic
2-ethyl-5-carboxypentyl phthalate[no description available]low00phthalic acid monoesterxenobiotic
carpropamid[no description available]low00amide fungicide;
cyclopropylcarboxamide;
monochlorobenzenes		antifungal agrochemical;
EC 4.2.1.94 (scytalone dehydratase) inhibitor;
melanin synthesis inhibitor;
xenobiotic
mesotrione[no description available]low00aromatic ketone;
beta-triketone;
C-nitro compound;
sulfone		carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
troleandomycin[no description available]low00acetate ester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyketide;
semisynthetic derivative		EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor;
xenobiotic
dronedarone[no description available]low001-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic
pinoxaden[no description available]low00pivalate ester;
pyrazolooxadiazepine		agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
environmental contaminant;
proherbicide;
xenobiotic
2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide[no description available]low00anilide fungicide;
biphenyls;
monochlorobenzenes;
pyridinecarboxamide		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
environmental contaminant;
xenobiotic
prizes[no description available]low00carboxamidine;
monochloropyridine;
nitrile		environmental contaminant;
neonicotinoid insectide;
xenobiotic
ritonavir[no description available]low001,3-thiazoles;
carbamate ester;
carboxamide;
L-valine derivative;
ureas		antiviral drug;
environmental contaminant;
HIV protease inhibitor;
xenobiotic
lenticin[no description available]low00amino-acid betaine;
indole alkaloid;
L-tryptophan derivative		fungal metabolite;
plant metabolite;
xenobiotic
cyanoginosin lr[no description available]low00microcystinbacterial metabolite;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
environmental contaminant;
xenobiotic
rosuvastatin[no description available]low00dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrimidines;
statin (synthetic);
sulfonamide		anti-inflammatory agent;
antilipemic drug;
cardioprotective agent;
CETP inhibitor;
environmental contaminant;
xenobiotic
mycophenolic acid[no description available]low002-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic
zithromax[no description available]low00macrolide antibioticantibacterial drug;
environmental contaminant;
xenobiotic
dieldrin[no description available]low00epoxide;
organochlorine compound;
organochlorine insecticide		carcinogenic agent;
xenobiotic
thiopental[no description available]low00barbituratesanticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic
ranitidine[no description available]low00C-nitro compound;
furans;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic
azoxystrobin[no description available]low00aryloxypyrimidine;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
methyl ester;
nitrile		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
quinone outside inhibitor;
xenobiotic
sitagliptin[no description available]low00triazolopyrazine;
trifluorobenzene		EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
environmental contaminant;
hypoglycemic agent;
serine proteinase inhibitor;
xenobiotic
tylosin[no description available]low00aldehyde;
disaccharide derivative;
enone;
leucomycin;
macrolide antibiotic;
monosaccharide derivative		allergen;
bacterial metabolite;
environmental contaminant;
xenobiotic
eprosartan[no description available]low00dicarboxylic acid;
imidazoles;
thiophenes		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
levetiracetam[no description available]low00pyrrolidin-2-onesanticonvulsant;
environmental contaminant;
xenobiotic
naltrexone[no description available]low00cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound		antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic
dextromethorphan[no description available]low006-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthreneantitussive;
environmental contaminant;
neurotoxin;
NMDA receptor antagonist;
oneirogen;
prodrug;
xenobiotic
kresoxim-methyl[no description available]low00aromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
pyrachlostrobin[no description available]low00aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
cilastatin[no description available]low00carboxamide;
L-cysteine derivative;
non-proteinogenic L-alpha-amino acid;
organic sulfide		EC 3.4.13.19 (membrane dipeptidase) inhibitor;
environmental contaminant;
protease inhibitor;
xenobiotic
microcystin rr[no description available]low00microcystin;
organic molecular entity		bacterial metabolite;
environmental contaminant;
xenobiotic
roxithromycin[no description available]low00roxithromycinenvironmental contaminant;
xenobiotic
yunaconitine[no description available]low00acetate ester;
aromatic ether;
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound		antifeedant;
human urinary metabolite;
phytotoxin;
plant metabolite;
xenobiotic
pymetrozine[no description available]low001,2,4-triazines;
pyridines		antifeedant;
environmental contaminant;
TRPV channel modulator;
xenobiotic
neotame[no description available]low00dipeptideenvironmental contaminant;
sweetening agent;
xenobiotic
flonicamid[no description available]low00nitrile;
organofluorine compound;
pyridinecarboxamide		environmental contaminant;
insecticide;
xenobiotic
microcystin-lf[no description available]low00microcystinbacterial metabolite;
environmental contaminant;
xenobiotic
decarbamylsaxitoxin[no description available]low00alkaloid;
guanidines;
ketone hydrate;
paralytic shellfish toxin;
primary alcohol;
pyrrolopurine		bacterial metabolite;
marine metabolite;
neurotoxin;
toxin;
xenobiotic
mephedrone[no description available]low00amphetamines;
aromatic ketone;
secondary amino compound		environmental contaminant;
xenobiotic
clothianidin[no description available]low001,3-thiazoles;
2-nitroguanidine derivative;
clothianidin;
organochlorine compound		environmental contaminant;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic
clozapine[no description available]low00benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
benzene[no description available]low00aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
formaldehyde[no description available]low00aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
naphthalene[no description available]low00naphthalenes;
ortho-fused bicyclic arene		apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component
phenanthrene[no description available]low00ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon;
phenanthrenes		environmental contaminant;
mouse metabolite
pyridine[no description available]low00azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
2,4,6-tribromophenol[no description available]low00bromophenolenvironmental contaminant;
fungicide;
marine metabolite
2,4-dichlorophenoxyacetic acid[no description available]low00chlorophenoxyacetic acid;
dichlorobenzene		agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin
4-nonylphenol[no description available]low00phenolsenvironmental contaminant
dibutyl phthalate[no description available]low00diester;
phthalate ester		EC 3.2.1.20 (alpha-glucosidase) inhibitor;
environmental contaminant;
metabolite;
plasticiser;
teratogenic agent
ethion[no description available]low00organic thiophosphateacaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide
methyl parathion[no description available]low00C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
genotoxin
bromodichloromethane[no description available]low00halomethaneenvironmental contaminant;
reagent
trichlorofluoromethane[no description available]low00chlorofluorocarbon;
halomethane		environmental contaminant;
NMR chemical shift reference compound;
NMR solvent;
refrigerant
tris(2-butoxyethyl) phosphate[no description available]low00trialkyl phosphateenvironmental contaminant;
flame retardant
cumene hydroperoxide[no description available]low00peroxolenvironmental contaminant;
Mycoplasma genitalium metabolite;
oxidising agent
1-nitronaphthalene[no description available]low00mononitronaphthaleneenvironmental contaminant;
mouse metabolite
2-nitrotoluene[no description available]low00mononitrotoluenecarcinogenic agent;
environmental contaminant
2-methyl-4-chlorophenoxyacetic acid[no description available]low00chlorophenoxyacetic acid;
monochlorobenzenes		environmental contaminant;
phenoxy herbicide;
synthetic auxin
benzotrifluoride[no description available]low00(trifluoromethyl)benzenes;
fluorohydrocarbon		environmental contaminant;
NMR chemical shift reference compound;
solvent
n-nitrosopiperidine[no description available]low00nitrosamine;
piperidine		apoptosis inducer;
carcinogenic agent;
environmental contaminant;
mutagen
cyclamic acid[no description available]low00sulfamic acidsenvironmental contaminant;
human xenobiotic metabolite
1,3-dichloropropane[no description available]low00chloroalkane;
chlorohydrocarbon		environmental contaminant;
nematicide
malachite green[no description available]low00organic chloride saltantibacterial agent;
antifungal drug;
carcinogenic agent;
environmental contaminant;
fluorochrome;
histological dye;
teratogenic agent
2,6-dimethylnaphthalene[no description available]low00dimethylnaphthaleneenvironmental contaminant
brilliant green[no description available]low00organic hydrogensulfate saltantibacterial agent;
antiseptic drug;
environmental contaminant;
fluorochrome;
histological dye;
poison
ametryne[no description available]low00diamino-1,3,5-triazine;
methylthio-1,3,5-triazine		environmental contaminant;
herbicide
3-methylfuran[no description available]low00furans;
volatile organic compound		Aspergillus metabolite;
environmental contaminant;
fungal metabolite;
Penicillium metabolite;
plant metabolite
bpmc[no description available]low00carbamate esteragrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
herbicide;
insecticide
pirimiphos methyl[no description available]low00aminopyrimidine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide
pendimethalin[no description available]low00C-nitro compound;
secondary amino compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide
isoprothiolane[no description available]low00dithiolanes;
isopropyl ester;
malonate ester		antifungal agrochemical;
environmental contaminant;
insecticide;
phospholipid biosynthesis inhibitor
perfluorododecanoic acid[no description available]low00fluoroalkanoic acidenvironmental contaminant
t-2 toxin[no description available]low00acetate ester;
organic heterotetracyclic compound;
trichothecene		apoptosis inducer;
cardiotoxic agent;
DNA synthesis inhibitor;
environmental contaminant;
fungal metabolite;
mycotoxin;
neurotoxin
6-[(phenylmethylthio)methyl]imidazo[2,1-b]thiazole[no description available]low00imidazothiazole
ConditionIndicatedRelationship StrengthStudiesTrials
47,XX,+210low20
47,XY,+210low20
Abscess, Amebic0low10
Absence Seizure0low10
Absence Seizures0low10
Acanthamebiasis0low10
Acanthamoeba Infection0low10
Acariasis0low10
Adjuvant Arthritis0low10
Aging0medium21
Allergic Encephalomyelitis0low20
Allergic Encephalomyelitis, Experimental0low20
ALS - Amyotrophic Lateral Sclerosis0low10
Amebiasis0low10
Ameboma0low10
Amoebiasis0low10
Amyotrophic Lateral Sclerosis0low10
Amyotrophic Lateral Sclerosis With Dementia0low10
Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex 10low10
Amyotrophic Lateral Sclerosis, Guam Form0low10
Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia Complex of Guam0low10
Ancylostomiasis0low40
Anemia, Fanconi0low10
Angiostrongylus Infections0low30
Anguilluliasis0low40
Animal Diseases0low10
Anterior Optic Neuritis0low10
Aortic Diseases0low10
Arthritis0low10
Arthritis, Adjuvant0low10
Arthritis, Adjuvant-Induced0low10
Arthritis, Collagen-Induced0low10
Arthritis, Experimental0low10
Ascariasis0medium214
Ascaridiasis0low20
Ascaris Infection0medium214
Aspiculariasis0low30
Atonic Absence Seizure0low10
Atonic Absence Seizures0low10
Atonic Seizure0low10
Atonic Seizures0low10
Autoimmune Encephalomyelitis, Experimental0low20
Autoimmune Experimental Encephalomyelitis0low20
Avian Diseases0low20
Bacterial Disease0low10
Bacterial Infection0low10
Bacterial Infections0low10
Balamuthia Infection0low10
Behavior Disorders0low10
Benign Neoplasms0low10
Benign Neoplasms, Brain0low10
Bertielliasis0low30
Besnoitiasis0low10
Besnoitiosis0low10
Bilharziasis0low10
Bird Diseases0low20
Bladder Cancer0low10
Bladder Neoplasms0low10
Bladder Tumors0low10
Body Weight0medium101
Bone Loss, Osteoclastic0low10
Bone Resorption0low10
Bovine Diseases0low140
Brain Cancer0low10
Brain Diseases0low10
Brain Disorders0low10
Brain Inflammation0low30
Brain Metastases0low10
Brain Neoplasm, Primary0low10
Brain Neoplasms0low10
Brain Neoplasms, Benign0low10
Brain Neoplasms, Malignant0low10
Brain Neoplasms, Malignant, Primary0low10
Brain Neoplasms, Primary Malignant0low10
Brain Tumor, Primary0low10
Brain Tumor, Recurrent0low10
Brain Tumors0low10
Bunostomiasis0low40
Calcification, Pathologic0low30
Calcinosis0low30
Calcinosis, Tumoral0low30
Cancer0low10
Cancer of Bladder0low10
Cancer of Brain0low10
Cancer of Liver0low10
Cancer of Lung0low20
Cancer of the Bladder0low10
Cancer of the Brain0low10
Cancer of the Liver0low10
Cancer of the Lung0low20
Cancer, Hepatocellular0low10
Canine Diseases0low20
Caprine Diseases0low10
Carcinoma0low10
Carcinoma, Anaplastic0low10
Carcinoma, Spindle-Cell0low10
Carcinoma, Undifferentiated0low10
Carcinomatosis0low10
Cartilage Diseases0low10
Cat Diseases0low10
Cattle Diseases0low140
Cell Transformation, Neoplastic0low20
Central Nervous System Disorders, Intracranial0low10
Central Nervous System Intracranial Disorders0low10
Cenuriasis0low30
Cestode Infections0low30
Charcot Disease0low10
Chondromalacia0low10
Chronic Disease0low20
Chronic Illness0low20
Chronically Ill0low20
Clonic Seizure0low10
Clonic Seizures0low10
Clostridium tetani Infection0low10
CNS Disorders, Intracranial0low10
Cocaine Abuse0low10
Cocaine Addiction0low10
Cocaine Dependence0low10
Cocaine-Related Disorders0low10
Coccidiosis0low10
Coenuriasis0low30
Colitis Gravis0low10
Colitis, Ulcerative0low10
Collagen Arthritis0low10
Complex Partial Seizure0low10
Complex Partial Seizures0low10
Complications, Infectious Pregnancy0low10
Complications, Pregnancy0low20
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Contact Dermatitis0low10
Convulsion0low10
Convulsion, Non-Epileptic0low10
Convulsions0low10
Convulsive Seizure0low10
Convulsive Seizures0low10
Cystic Fibrosis0low10
Cystic Fibrosis of Pancreas0low10
Delayed Hypersensitivity0low10
Dementia With Amyotrophic Lateral Sclerosis0low10
Dermatitis Venenata0low10
Dermatitis, Contact0low10
Dermatitis, Eczematous0low10
Dermatitis, Occupational0low20
Dermatomyositis0low10
Dermatomyositis, Adult Type0low10
Dermatomyositis, Childhood Type0low10
Dermatopolymyositis0low10
Dermatosis, Industrial0low20
Di Guglielmo Disease0low10
Di Guglielmo's Disease0low10
Diagnosis, Psychiatric0low10
Dicrocoeliasis0low10
Dictyocauliasis0low30
Dictyocaulus Infections0low30
Dipylidiasis0low30
Dirofilariasis0low10
Disease Models, Animal0low30
Diseases, Animal0low10
Dog Diseases0low20
Down Syndrome0low20
Down Syndrome, Partial Trisomy 210low20
Down's Syndrome0low20
Drug-Induced Stevens Johnson Syndrome0low10
Drug-Induced Stevens-Johnson Syndrome0low10
Dysembryoma0low10
Ectoparasitic Infestations0low10
Eczema0low10
Eczema, Contact0low10
Elaeophoriasis0medium21
Encephalitis0low30
Encephalitis, Polio0low10
Encephalitis, Rasmussen0low30
Encephalomyelitis, Allergic0low20
Encephalomyelitis, Autoimmune, Experimental0low20
Encephalomyelitis, Experimental Autoimmune0low20
Encephalon Diseases0low10
Encephalopathy0low10
Epidemic Acute Poliomyelitis0low10
Epidermal Necrolysis, Toxic0low10
Epileptic Seizure0low10
Epileptic Seizures0low10
Epithelial Neoplasms, Malignant0low10
Epithelial Tumors, Malignant0low10
Epithelioma0low10
Equine Diseases0low50
Equine Strongyle Infections0low10
Erythremic Myelosis0low10
Erythroblastic Leukemia, Acute0low10
Erythroleukemia0low10
Experimental Allergic Encephalomyelitis0low20
Experimental Autoimmune Encephalomyelitis0low20
Experimental Leukemia0low30
Experimental Leukemias0low30
Experimental Lung Inflammation0low10
Experimental Neoplasms0low20
Extravascular Hemolysis0low10
Eye Diseases0low20
Eye Disorders0low20
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Fasciola Infection0low40
Fascioliasis0low40
Fasciolopsiasis0low20
Feline Diseases0low10
Fetal Death0low10
Fetal Demise0low10
Fetal Mummification0low10
Fever, Zika0low10
Fibrocystic Disease of Pancreas0low10
Filariasis0medium21
Filarioidea Infections0medium21
Foreign Bodies0low10
Foreign Objects0low10
Gastric Diseases0low10
Gastroenteritis0low20
Gehrig's Disease0low10
Generalized Absence Seizure0low10
Generalized Absence Seizures0low10
Generalized Tonic-Clonic Seizures0low10
Giardia duodenalis Infection0low10
Giardia Infection0low10
Giardia intestinalis Infection0low10
Giardia lamblia Infection0low10
Giardiasis0low10
Goat Diseases0low10
Gossypiboma0low10
Granuloma0low10
Granulomas0low10
Guam Disease0low10
Guam Form of Amyotrophic Lateral Sclerosis0low10
Haemolysis0low10
Haemonchiasis0medium42
Hansen Disease0low10
Hansen's Disease0low10
Heartworm Disease0low10
Helminthiasis0low110
Helminthiasis, Animal0low100
Hemolysis0low10
Hepatic Cancer0low10
Hepatic Neoplasms0low10
Hepatitis0low10
Hepatoblastoma0low10
Hepatocellular Cancer0low10
Hookworm Infections0low40
Horse Diseases0low50
Human Trichinellosis0low10
Hymenolepiasis0low10
Hymenolepis Infection0low10
Hypersensitivity, Contact0low10
Hypersensitivity, Delayed0low10
Hypersensitivity, Tuberculin-Type0low10
Hypersensitivity, Type IV0low10
Idiopathic Inflammatory Myopathies0low10
Idiopathic Inflammatory Myopathy0low10
Idiopathic Inflammatory Myositis0low10
Idiopathic Proctocolitis0low10
Industrial Dermatosis0low20
Infantile Paralysis0low10
Infection0low20
Infection and Infestation0low20
Infection, Bacterial0low10
Infections0low20
Infections and Infestations0low20
Infections, Bacterial0low10
Infections, Dictyocaulus0low30
Infections, Equine Strongyle0low10
Infections, Filarioidea0medium21
Infections, Hookworm0low40
Infections, Nematode0low240
Infections, Nematomorpha0low110
Infections, Respiratory0low10
Infections, Respiratory Tract0low10
Infections, Stephanurus dentatus0low30
Infections, Strongylida0low30
Infections, Taenia0low10
Infections, Trematode0low20
Infections, Trichomonas0low10
Infections, Upper Respiratory0low10
Infections, Upper Respiratory Tract0low10
Infectious Myositis0low10
Infectious Pregnancy Complications0low10
Inflammation, Brain0low30
Inflammatory Bowel Disease, Ulcerative Colitis Type0low10
Inflammatory Muscle Diseases0low10
Inflammatory Myopathies, Idiopathic0low10
Inflammatory Myopathy0low10
Inflammatory Myopathy, Idiopathic0low10
Intestinal Diseases, Parasitic0low70
Intracranial Central Nervous System Disorders0low10
Intracranial CNS Disorders0low10
Intracranial Neoplasms0low10
Intravascular Hemolysis0low10
Iodamoebiasis0low10
Itching0low10
Jacksonian Seizure0low10
Juvenile Dermatomyositis0low10
Juvenile Myositis0low10
Katayama Fever0low10
Keratoconjunctivitis0low10
Lambliasis0low10
Leprosy0low10
Leukemia L 12100low10
Leukemia L12100low10
Leukemia Model, Animal0low30
Leukemia, Erythroblastic, Acute0low10
Leukemia, Experimental0low30
Leukemia, Lymphocytic0low10
Leukemia, Lymphoid0low10
Leukemia, Myeloid, Acute, M60low10
Leukemias, Experimental0low30
Liver Cancer0low10
Liver Neoplasms0low10
Lobar Pneumonia0low10
Lou Gehrig Disease0low10
Lou Gehrig's Disease0low10
Lou-Gehrigs Disease0low10
Lung Cancer0low20
Lung Diseases, Parasitic0low10
Lung Inflammation0low10
Lung Neoplasms0low20
Lyell's Syndrome0low10
Lymphatic Diseases0medium11
Lymphatism0medium11
Lymphocytic Leukemia0low10
Lymphoid Leukemia0low10
Malignancy0low10
Malignant Epithelial Neoplasms0low10
Malignant Neoplasms0low10
Malignant Neoplasms, Brain0low10
Malignant Primary Brain Neoplasms0low10
Malignant Primary Brain Tumors0low10
Malignant Tumor of Urinary Bladder0low10
Mange0low10
Marasmus0medium11
Mastitis, Bovine0low20
Maternal Sepsis0low10
Meningitis, Tuberculous0low10
Mental Disorders0low10
Mental Disorders, Severe0low10
Mental Illness0low10
Metagonimiasis0low20
Microcalcification0low30
Microcalcinosis0low30
Mite Infestations0low10
MODS0low10
Mongolism0low20
Monkey Diseases0low10
Motor Neuron Disease, Amyotrophic Lateral Sclerosis0low10
Mucoviscidosis0low10
Multiple Organ Dysfunction Syndrome0low10
Multiple Organ Failure0low10
Muscle Contraction0low20
Muscle Diseases, Inflammatory0low10
Mycoplasma-Induced Stevens Johnson Syndrome0low10
Mycoplasma-Induced Stevens-Johnson Syndrome0low10
Myeloid Leukemia, Acute, M60low10
Myoclonic Seizure0low10
Myoclonic Seizures0low10
Myopathies, Idiopathic Inflammatory0low10
Myopathy, Inflammatory0low10
Myositis0low10
Myositis, Focal0low10
Myositis, Infectious0low10
Myositis, Proliferative0low10
Necatoriasis0low30
Nematode Infections0low240
Nematomorpha Infections0low110
Neoplasia0low10
Neoplasm0low10
Neoplasms0low10
Neoplasms, Benign0low10
Neoplasms, Bladder0low10
Neoplasms, Brain0low10
Neoplasms, Brain, Benign0low10
Neoplasms, Brain, Malignant0low10
Neoplasms, Brain, Primary0low10
Neoplasms, Experimental0low20
Neoplasms, Hepatic0low10
Neoplasms, Intracranial0low10
Neoplasms, Liver0low10
Neoplasms, Lung0low20
Neoplasms, Malignant Epithelial0low10
Neoplasms, Pulmonary0low20
Neoplastic Cell Transformation0low20
Neoplastic Transformation, Cell0low20
Nervous System Diseases0low10
Nervous System Disorders0low10
Neurologic Disorders0low10
Neurological Disorders0low10
Neuropapillitis0low10
Non-Epileptic Seizure0low10
Non-Epileptic Seizures0low10
Nonepileptic Seizure0low10
Nonepileptic Seizures0low10
Nonstaphylococcal Scalded Skin Syndrome0low10
Occupational Dermatitis0low20
Oesophagostomiasis0low20
Optic Neuritis0low10
Orchitis0low10
Organ Dysfunction Syndrome, Multiple0low10
Organ Failure, Multiple0low10
Osteoclastic Bone Loss0low10
Ostertagiasis0low10
Ovine Diseases0medium252
Oxyuriasis0low30
Pancreatic Cystic Fibrosis0low10
Parasite Infections0medium41
Parasitic Diseases0medium41
Parasitic Diseases, Animal0medium41
Parasitic Infections0medium41
Parasitic Infections of Lung0low10
Parasitic Infections, Animal0medium41
Parasitic Intestinal Diseases0low70
Parasitic Lung Diseases0low10
Partial Seizure0low10
Partial Seizures0low10
Partial Trisomy 21 Down Syndrome0low20
Pathologic Calcification0low30
Petit Mal Convulsion0low10
Pneumonia0low10
Pneumonia, Lobar0low10
Pneumonitis0low10
Polio0low10
Polio Encephalitis0low10
Poliomyelitis0low10
Poliomyelitis Infection0low10
Poliomyelitis, Acute0low10
Poliomyelitis, Nonpoliovirus0low10
Poliomyelitis, Preparalytic0low10
Polyarthritis0low10
Polymyositis-Dermatomyositis0low10
Posterior Optic Neuritis0low10
Poultry Diseases0low50
Pregnancy0low110
Pregnancy Complications0low20
Pregnancy Complications, Infectious0low10
Pregnancy, Infectious Complications0low10
Primary Brain Neoplasms0low10
Primary Malignant Brain Neoplasms0low10
Primary Malignant Brain Tumors0low10
Protein-Calorie Malnutrition0medium11
Protein-Energy Malnutrition0medium11
Pruritis0low10
Pruritus0low10
Psychiatric Diagnosis0low10
Psychiatric Diseases0low10
Psychiatric Disorders0low10
Psychiatric Illness0low10
Pulmonary Cancer0low20
Pulmonary Cystic Fibrosis0low10
Pulmonary Inflammation0low10
Pulmonary Neoplasms0low20
Pulmonary Parasitic Infections0low10
Rachitis0low20
Raillietiniasis0low30
Rasmussen Encephalitis0low30
Rasmussen Syndrome0low30
Rasmussen's Syndrome0low30
Recrudescence0medium11
Recurrence0medium11
Relapse0medium11
Remission, Spontaneous0low10
Respiratory Infections0low10
Respiratory Tract Infections0low10
Retained Surgical Instruments0low10
Retained Surgical Items0low10
Retained Surgical Needle0low10
Retained Surgical Sponge0low10
Retained Surgical Tools0low10
Retrobulbar Neuritis0low10
Rhabdomyolysis0low10
Rheumatic Diseases0low10
Rheumatism0low10
Rickets0low20
Sarcoma 1800low30
Sarcoma 180, Crocker0low30
Scalded Skin Syndrome, Nonstaphylococcal0low10
Schistoma Infection0low10
Schistosomiasis0low10
Seizure0low10
Seizures0low10
Seizures, Auditory0low10
Seizures, Clonic0low10
Seizures, Convulsive0low10
Seizures, Epileptic0low10
Seizures, Focal0low10
Seizures, Generalized0low10
Seizures, Gustatory0low10
Seizures, Motor0low10
Seizures, Olfactory0low10
Seizures, Sensory0low10
Seizures, Somatosensory0low10
Seizures, Tonic0low10
Seizures, Tonic-Clonic0low10
Seizures, Vertiginous0low10
Seizures, Vestibular0low10
Seizures, Visual0low10
Sensitivity and Specificity0low30
Sensitivity, Contact0low10
Sepsis during Pregnancy0low10
Sepsis in Pregnancy0low10
Setariasis0low10
Sheep Diseases0medium252
Single Seizure0low10
Status Lymphaticus0medium11
Stephanurus dentatus Infections0low30
Stevens Johnson Syndrome Toxic Epidermal Necrolysis0low10
Stevens Johnson Syndrome Toxic Epidermal Necrolysis Spectrum0low10
Stevens-Johnson Syndrome0low10
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis0low10
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum0low10
Stomach Diseases0low10
Strongyle Infections, Equine0low10
Strongylida Infections0low30
Strongyloidiasis0low40
Strongylosis, Equine0low10
Swine Diseases0low80
Syngamiasis0low30
Taenia brauni Infection0low10
Taenia glomeratus Infection0low10
Taenia Infections0low10
Taenia multiceps Infection0low10
Taenia serialis Infection0low10
Taenia solium Infection0low10
Taeniasis0low10
Tapeworm Infection0low30
TB Meningitis0low10
Teratoid Tumor0low10
Teratoma0low10
Teratoma, Benign0low10
Teratoma, Cystic0low10
Teratoma, Immature0low10
Teratoma, Malignant0low10
Teratoma, Mature0low10
Tetanus0low10
Textiloma0low10
Tick Infestations0low10
Tonic Clonic Seizure0low10
Tonic Seizure0low10
Tonic Seizures0low10
Tonic-Clonic Seizure0low10
Tonic-Clonic Seizures0low10
Toxic Epidermal Necrolysis0low10
Toxic Epidermal Necrolysis Stevens Johnson Syndrome0low10
Toxic Epidermal Necrolysis Stevens Johnson Syndrome Spectrum0low10
Toxic Epidermal Necrolysis Stevens-Johnson Syndrome0low10
Toxic Epidermal Necrolysis Stevens-Johnson Syndrome Spectrum0low10
Toxocariasis0low10
Transformation, Neoplastic Cell0low20
Trematode Infections0low20
Trichinelliasis0low10
Trichinellosis0low10
Trichinosis0low10
Trichocephaliasis0low40
Trichomonas Infections0low10
Trichomoniasis0low10
Trichostrongyloidiasis0low90
Trichostrongylosis0low10
Trichuriasis0low40
Trichuris Infection0low40
Trichuris trichiura Infection0low40
Trisomy 210low20
Trisomy 21, Meiotic Nondisjunction0low20
Trisomy 21, Mitotic Nondisjunction0low20
Trisomy G0low20
Tubercular Meningitis0low10
Tuberculin-Type Hypersensitivity0low10
Tuberculosis Meningitis0low10
Tuberculosis, Meningeal0low10
Tuberculous Hypertrophic Pachymeningitis0low10
Tumorigenic Transformation0low20
Tumors0low10
Type IV Hypersensitivity0low10
Ulcerative Colitis0low10
Upper Respiratory Infections0low10
Upper Respiratory Tract Infection0low10
Upper Respiratory Tract Infections0low10
Urinary Bladder Cancer0low10
Urinary Bladder Neoplasms0low10
Whipworm Infection0low40
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
[Toxicity of "Farmakhim" tetramisole in laboratory and farm animals].
Veterinarno-meditsinski nauki, Volume: 19, Issue: 1		1982
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Chiral pharmacokinetics of tetramisole stereoisomers-Enantioselective quantification of levamisole and dexamisole in serum samples from users of adulterated cocaine.
Drug testing and analysis, Volume: 14, Issue: 6		2022
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (10)

ArticleYear
Facile colorimetric methods for the quantitative determination of tetramisole hydrochloride.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, Volume: 58, Issue: 12		2002
Comparative anthelmintic activity of strategic sustained low-level administration of albendazole in feed pellets compared to single doses of closantel and tetramisole against natural ovine parasitic gastroenteritis.
Tropical animal health and production, Volume: 31, Issue: 4		1999
Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962.
American journal of veterinary research, Volume: 54, Issue: 3		1993
[Udder compatibility of tetramisole and levamisole hydrochloride and suggestion for the prescription of their intramammary use in cattle against Prototheca zopfii].
Berliner und Munchener tierarztliche Wochenschrift, Volume: 106, Issue: 8		1993
Effect of L- and D-tetramisole on 32Pi and 45Ca uptake and mineralization by matrix vesicle-enriched fractions from chicken epiphyseal cartilage.
The Journal of biological chemistry, Jan-25, Volume: 259, Issue: 2		1984
Response of preadult Necator americanus to some known anthelmintics in hamsters.
Chemotherapy, Volume: 32, Issue: 1		1986
Treatment of Nippostrongylus brasiliensis in normal and SPF rats using tetramisole loaded into zeolite.
Journal of helminthology, Volume: 66, Issue: 4		1992
Influence of anthelmintic treatment on the liveweight of outwintered ewe hoggs.
The Veterinary record, Jan-04, Volume: 96, Issue: 1		1975
On the possible anti-rheumatic effects (immuno-effector?)of imidazole derivatives (levamisole, clotrimazole, niridazole).
Biomedicine / [publiee pour l'A.A.I.C.I.G.], Volume: 27, Issue: 3		1977
Partial inhibition of primary lung tumourigenesis by tetramisole.
Cancer letters, Volume: 2, Issue: 4-5		1977
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]