diethylnitrosamine has been researched along with Sensitivity and Specificity in 10 studies
Diethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
N-nitrosodiethylamine : A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we explored whether treatment with FGF-21 could prevent diethylnitrosamine (DEN) induced hepatocarcinogenesis in mice." | 3.81 | Long-Term Administration of Fibroblast Growth Factor 21 Prevents Chemically-Induced Hepatocarcinogenesis in Mice. ( Li, D; Liu, M; Liu, Z; Rasoul, LM; Ren, G; Wang, W; Wu, Q; Xu, P; Ye, X; Yuan, Q; Zhang, Y, 2015) |
| "The ability of diethylnitrosamine (DENA) to initiate and phenobarbital to promote altered-hepatocyte foci and hepatocellular carcinomas in C3H and C3B6F1 (C3H x C57BL/6) mice was compared to the extent of cell proliferation." | 3.68 | Comparison in C3H and C3B6F1 mice of the sensitivity to diethylnitrosamine-initiation and phenobarbital-promotion to the extent of cell proliferation. ( Pereira, MA, 1993) |
| "Liver cirrhosis is a predominant risk factor for hepatocellular carcinoma (HCC)." | 1.42 | Evaluation of 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in rat models with hepatocellular carcinoma with liver cirrhosis. ( Chung, YA; Ham, HJ; Jang, KS; Jung, YJ; Lee, J; Lee, JH; Maeng, LS; Park, MS; Park, SI, 2015) |
| "The percentage of liver fibrosis was assessed via quantitative analysis of Masson trichrome staining using an average of 30 fields per section." | 1.39 | Intra-voxel incoherent motion MRI in rodent model of diethylnitrosamine-induced liver fibrosis. ( Deng, J; Guo, Y; Jin, N; Larson, AC; Omary, RA; White, SB; Yang, GY; Zhang, Y, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Souza, JC | 1 |
| Sultan, LR | 1 |
| Hunt, SJ | 1 |
| Schultz, SM | 1 |
| Brice, AK | 1 |
| Wood, AKW | 1 |
| Sehgal, CM | 1 |
| Zhang, Y | 2 |
| Jin, N | 2 |
| Deng, J | 2 |
| Guo, Y | 1 |
| White, SB | 1 |
| Yang, GY | 2 |
| Omary, RA | 2 |
| Larson, AC | 2 |
| Xu, P | 1 |
| Wang, W | 1 |
| Yuan, Q | 1 |
| Liu, Z | 1 |
| Rasoul, LM | 1 |
| Wu, Q | 1 |
| Liu, M | 1 |
| Ye, X | 1 |
| Li, D | 1 |
| Ren, G | 1 |
| Park, SI | 1 |
| Lee, JH | 1 |
| Ham, HJ | 1 |
| Jung, YJ | 1 |
| Park, MS | 1 |
| Lee, J | 1 |
| Maeng, LS | 1 |
| Chung, YA | 1 |
| Jang, KS | 1 |
| Yin, X | 1 |
| Zhang, Z | 1 |
| Qiu, W | 1 |
| Wang, X | 1 |
| Leibowitz, B | 1 |
| Yang, W | 1 |
| Zhang, L | 1 |
| Yu, J | 1 |
| Ripollés, C | 1 |
| Pitarch, E | 1 |
| Sancho, JV | 1 |
| López, FJ | 1 |
| Hernández, F | 1 |
| Pereira, MA | 1 |
| Parton, JW | 1 |
| Garriott, ML | 1 |
| Kushida, H | 1 |
| Fujita, K | 1 |
| Suzuki, A | 1 |
| Yamada, M | 1 |
| Nohmi, T | 1 |
| Kamataki, T | 1 |
10 other studies available for diethylnitrosamine and Sensitivity and Specificity
| Article | Year |
|---|---|
B-mode ultrasound for the assessment of hepatic fibrosis: a quantitative multiparametric analysis for a radiomics approach.
Topics: Animals; Biopsy; Body Weight; Carcinoma, Hepatocellular; Diethylnitrosamine; Hepatic Veins; Humans; | 2019 |
Intra-voxel incoherent motion MRI in rodent model of diethylnitrosamine-induced liver fibrosis.
Topics: Animals; Artifacts; Diethylnitrosamine; Disease Models, Animal; Humans; Image Enhancement; Image Int | 2013 |
Long-Term Administration of Fibroblast Growth Factor 21 Prevents Chemically-Induced Hepatocarcinogenesis in Mice.
Topics: Animals; Blotting, Western; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prolif | 2015 |
Evaluation of 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in rat models with hepatocellular carcinoma with liver cirrhosis.
Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Feasibility Studies; Fluorodeoxyglucose F18; | 2015 |
Quantitative multiparametric PROPELLER MRI of diethylnitrosamine-induced hepatocarcinogenesis in wister rat model.
Topics: Algorithms; Animals; Diethylnitrosamine; Disease Models, Animal; Humans; Image Enhancement; Image In | 2010 |
PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Biopsy, Needle; Blotting, W | 2011 |
Determination of eight nitrosamines in water at the ng L(-1) levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry.
Topics: Atmospheric Pressure; Chromatography, Liquid; Diethylnitrosamine; Dimethylnitrosamine; Drinking Wate | 2011 |
Comparison in C3H and C3B6F1 mice of the sensitivity to diethylnitrosamine-initiation and phenobarbital-promotion to the extent of cell proliferation.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Cell Division; Diethylnitrosamine; Female; Liver; Liver | 1993 |
An evaluation of micronucleus induction in bone marrow and in hepatocytes isolated from collagenase perfused liver or from formalin-fixed liver using four-week-old rats treated with known clastogens.
Topics: Age Factors; Animals; Bone Marrow; Collagenases; Diethylnitrosamine; Dose-Response Relationship, Dru | 1997 |
Development of a Salmonella tester strain sensitive to promutagenic N-nitrosamines: expression of recombinant CYP2A6 and human NADPH-cytochrome P450 reductase in S. typhimurium YG7108.
Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme S | 2000 |