Glycogen phosphorylase, muscle form

A glycogen phosphorylase, muscle form that is encoded in the genome of human. [PRO:DNx, UniProtKB:P11217]

EC 2.4.1.1;
Myophosphorylase

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
cyproheptadine	Homo sapiens (human)	Ki	0.0040	1	1
spiperone	Homo sapiens (human)	Ki	49.6000	1	1
butaclamol	Homo sapiens (human)	Ki	5.2000	1	1
glucose	Homo sapiens (human)	Ki	1,700.0000	1	1
gl-4	Homo sapiens (human)	Ki	8.0000	2	2
bosutinib	Homo sapiens (human)	IC50	0.0012	1	1
tak-715	Homo sapiens (human)	IC50	10.0000	1	1
maltoheptaose	Homo sapiens (human)	Ki	1,000.0000	1	1

This protein enables 6 target(s):

Target	Category	Definition
nucleotide binding	molecular function	Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. [GOC:mah, ISBN:0198547684]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
glycogen phosphorylase activity	molecular function	Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate. [EC:2.4.1.1, MetaCyc:GLYCOPHOSPHORYL-RXN]
linear malto-oligosaccharide phosphorylase activity	molecular function	Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide. [EC:2.4.1.1, GOC:pz]
SHG alpha-glucan phosphorylase activity	molecular function	Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan. [GOC:pz, RHEA:41732]
pyridoxal phosphate binding	molecular function	Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. [GOC:mah, ISBN:0198506732]

This protein is located in 2 target(s):

Target	Category	Definition
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
extracellular exosome	cellular component	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]

This protein is active in 1 target(s):

Target	Category	Definition
cytoplasm	cellular component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]

This protein is involved in 2 target(s):

Target	Category	Definition
glycogen metabolic process	biological process	The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. [ISBN:0198506732]
glycogen catabolic process	biological process	The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. [ISBN:0198506732]