Octyl 2-cyanoacrylate, also known as 2-octyl cyanoacrylate, is a monomer commonly used as an adhesive. It is synthesized through a reaction of octyl alcohol with 2-cyanoacrylic acid, typically in the presence of a catalyst. The reaction is exothermic, meaning it releases heat. Octyl 2-cyanoacrylate is a strong, fast-acting adhesive that forms a durable bond on a variety of surfaces, including skin, plastics, metals, and glass. Its strong adhesion and rapid curing make it suitable for industrial applications, such as in the production of adhesives, sealants, and coatings. The compound is also commonly used in medical applications for tissue bonding and wound closure. However, its use in healthcare can be limited due to its strong adhesion and the potential for irritation or allergic reactions. Octyl 2-cyanoacrylate is also studied for its potential applications in the field of biomaterials, particularly for tissue engineering and drug delivery. Researchers are investigating ways to modify its properties, such as reducing its adhesive strength and enhancing its biocompatibility, to optimize its suitability for these applications.'
| ID Source | ID |
|---|---|
| PubMed CID | 23167 |
| CHEMBL ID | 2105181 |
| SCHEMBL ID | 29891 |
| MeSH ID | M0264527 |
| Synonym |
|---|
| D05219 |
| ocrylate (usan/inn) |
| 6701-17-3 |
| ocrilate |
| ocrylate |
| octyl 2-cyanoprop-2-enoate |
| 2-octyl cyanocrylate |
| CHEMBL2105181 |
| ocrilatum [inn-latin] |
| einecs 229-748-8 |
| ocrilato [inn-spanish] |
| ocrilat |
| ocrilatum |
| unii-6c655p1xvg |
| octyl 2-cyanoacrylate |
| ocrylate [usan] |
| 2-propenoic acid, 2-cyano-, octyl ester |
| 6c655p1xvg , |
| octyl-2-cyanoacrylate |
| octyl (2-cyanacylat) |
| ocrilato |
| ocrilate [inn] |
| octyl cyanoacrylate |
| octyl cyanoacrylate [mi] |
| ocrilate [who-dd] |
| 2-octyl cyanocrylate [vandf] |
| ocrilate [mart.] |
| SCHEMBL29891 |
| RPQUGMLCZLGZTG-UHFFFAOYSA-N |
| DTXSID10217208 |
| DB15086 |
| Q7077122 |
| FT-0775200 |
| mfcd00868122 |
| SY318615 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " The effect on cell proliferation and viability in response to extracts prepared from capsule-embedded and commercial bone cements were not significantly different from each other, whereas extracts from OCA were moderately toxic to cells." | ( Mechanical and cytotoxicity testing of acrylic bone cement embedded with microencapsulated 2-octyl cyanoacrylate. Brochu, AB; Evans, GA; Reichert, WM, 2014) | 0.4 |
| "The use of ZT glue is a safe and effective method for the localization of small pulmonary nodules." | ( A safe and novel method for video-assisted thoracic surgery preoperative localization of small pulmonary nodules by using ZT medical glue (2-octyl cyanoacrylate). Ma, Z; Wang, B; Wang, T; Yu, G; Zeng, Y; Zhao, Z, 2020) | 0.56 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " Pharmacokinetic data were obtained from gingival crevicular fluid (GCF), saliva, and serum of adult periodontitis patients." | ( The pharmacokinetic profile of a biodegradable controlled-release delivery system containing doxycycline compared to systemically delivered doxycycline in gingival crevicular fluid, saliva, and serum. Garrett, S; Harrold, CQ; Johnson, LR; Stoller, NH; Trapnell, S, 1998) | 0.3 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (3.07) | 18.2507 |
| 2000's | 114 (34.97) | 29.6817 |
| 2010's | 151 (46.32) | 24.3611 |
| 2020's | 51 (15.64) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (30.21) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 73 (20.00%) | 5.53% |
| Reviews | 6 (1.64%) | 6.00% |
| Case Studies | 56 (15.34%) | 4.05% |
| Observational | 9 (2.47%) | 0.25% |
| Other | 221 (60.55%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|---|---|---|---|---|
| 1-butanol 1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.. butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes. | 2.03 | 1 | 0 | alkyl alcohol; primary alcohol; short-chain primary fatty alcohol | human metabolite; mouse metabolite; protic solvent |
| glutaral Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.. glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5. | 2.06 | 1 | 0 | dialdehyde | cross-linking reagent; disinfectant; fixative |
| hydroxyzine Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.. hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively. | 2.1 | 1 | 0 | hydroxyether; monochlorobenzenes; N-alkylpiperazine | anticoronaviral agent; antipruritic drug; anxiolytic drug; dermatologic drug; H1-receptor antagonist |
| resorcinol resorcinol: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7951. resorcinol : A benzenediol that is benzene dihydroxylated at positions 1 and 3. | 2.15 | 1 | 0 | benzenediol; phenolic donor; resorcinols | erythropoietin inhibitor; sensitiser |
| hydroxyproline Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.. hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group. | 2.02 | 1 | 0 | 4-hydroxyproline; L-alpha-amino acid zwitterion | human metabolite; mouse metabolite; plant metabolite |
| lysine Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine. | 2.11 | 1 | 0 | aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid | algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite |
| triamcinolone acetonide Triamcinolone Acetonide: An esterified form of TRIAMCINOLONE. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.. triamcinolone acetonide : A synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone. Used to treat various skin infections. | 2.1 | 1 | 0 | 11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; cyclic ketal; fluorinated steroid; glucocorticoid; primary alpha-hydroxy ketone | anti-allergic agent; anti-inflammatory drug |
| propylparaben Parabens: Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872) | 2.02 | 1 | 0 | benzoate ester; paraben; phenols | antifungal agent; antimicrobial agent |
| propylene propylene: structure | 2.05 | 1 | 0 | alkene; gas molecular entity | refrigerant; xenobiotic |
| n-butyl acrylate butyl acrylate : An acrylate ester obtained by the formal condensation of the hydroxy group of butan-1-ol with the carboxy group of acrylic acid. | 2.03 | 1 | 0 | acrylate ester | |
| durapatite Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.. hydroxylapatite : A phosphate mineral with the formula Ca5(PO4)3(OH). | 2 | 1 | 0 | ||
| d-alpha tocopherol Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.. tocopherol : A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.. vitamin E : Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.. (R,R,R)-alpha-tocopherol : An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. | 3.51 | 1 | 1 | alpha-tocopherol | algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite |
| bisphenol a-glycidyl methacrylate Bisphenol A-Glycidyl Methacrylate: The reaction product of bisphenol A and glycidyl methacrylate that undergoes polymerization when exposed to ultraviolet light or mixed with a catalyst. It is used as a bond implant material and as the resin component of dental sealants and composite restorative materials. | 2.08 | 1 | 0 | diarylmethane | |
| 2-octanol 2-octanol: RN given refers to cpd without isomeric designation. octan-2-ol : An octanol carrying the hydroxy group at position 2. | 2.03 | 1 | 0 | octanol; secondary alcohol | plant metabolite; volatile oil component |
| enbucrilate Enbucrilate: A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental. | 9.45 | 16 | 5 | alpha,beta-unsaturated monocarboxylic acid; nitrile | |
| silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA. | 2.11 | 1 | 0 | copper group element atom; elemental silver | Escherichia coli metabolite |
| titanium Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures. | 2.15 | 1 | 0 | titanium group element atom | |
| triamcinolone Triamcinolone: A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739). triamcinolone : A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections. | 2.17 | 1 | 0 | 11beta-hydroxy steroid; 16alpha-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid hormone; fluorinated steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone | anti-allergic agent; anti-inflammatory drug |
| alkenes [no description available] | 2.05 | 1 | 0 | ||
| cephalosporin c cephalosporin C: RN given refers to parent cpd; structure in Merck, 9th ed, #1937. cephalosporin C : A cephalosporin antibiotic carrying a 3-acetoxymethyl substituent and a 6-oxo-N(6)-L-lysino group at position 7. | 2.25 | 1 | 0 | cephalosporin | fungal metabolite |
| delphinidin Paraffin: A mixture of solid hydrocarbons obtained from petroleum. It has a wide range of uses including as a stiffening agent in ointments, as a lubricant, and as a topical anti-inflammatory. It is also commonly used as an embedding material in histology.. delphinidin chloride : An anthocyanidin chloride that has delphinidin as the cationic counterpart. | 3.99 | 1 | 1 | anthocyanidin chloride | |
| ethyl 2-cyanoacrylate ethyl 2-cyanoacrylate: RN given refers to monomer | 2.54 | 2 | 0 | ||
| nicotine (S)-nicotine : A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum. | 2.07 | 1 | 0 | 3-(1-methylpyrrolidin-2-yl)pyridine | anxiolytic drug; biomarker; immunomodulator; mitogen; neurotoxin; nicotinic acetylcholine receptor agonist; peripheral nervous system drug; phytogenic insecticide; plant metabolite; psychotropic drug; teratogenic agent; xenobiotic |
| povidone-iodine Povidone-Iodine: An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes. | 2.31 | 1 | 0 | ||
| picibanil Picibanil: A lyophilized preparation of a low-virulence strain (SU) of Streptococcus pyogenes (S. hemolyticus), inactivated by heating with penicillin G. It has been proposed as a noncytotoxic antineoplastic agent because of its immune system-stimulating activity. | 2.04 | 1 | 0 | penicillinate anion | |
| fumarates Fumarates: Compounds based on fumaric acid.. fumarate(2-) : A C4-dicarboxylate that is the E-isomer of but-2-enedioate(2-) | 2.13 | 1 | 0 | butenedioate; C4-dicarboxylate | human metabolite; metabolite; Saccharomyces cerevisiae metabolite |
| rivaroxaban Rivaroxaban: A morpholine and thiophene derivative that functions as a FACTOR XA INHIBITOR and is used in the treatment and prevention of DEEP-VEIN THROMBOSIS and PULMONARY EMBOLISM. It is also used for the prevention of STROKE and systemic embolization in patients with non-valvular ATRIAL FIBRILLATION, and for the prevention of atherothrombotic events in patients after an ACUTE CORONARY SYNDROME.. rivaroxaban : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery. | 2.17 | 1 | 0 | aromatic amide; lactam; monocarboxylic acid amide; morpholines; organochlorine compound; oxazolidinone; thiophenes | anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor |
| methyl orange methyl orange: indictor of pH with strong acids & bases; also used as reagent to form ion pairs with, and thereby isolate, certain compounds from biological material; minor descriptor (75-86); on-line & INDEX MEDICUS search AZO COMPOUNDS (75-86); file maintained to Azo cpds | 2.05 | 1 | 0 | ||
| warfarin Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 2.17 | 1 | 0 | benzenes; hydroxycoumarin; methyl ketone | |
| orabase Orabase: used in therapy of oral mucosal ulcers | 4.64 | 3 | 2 |
| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|---|---|---|---|
| Allergic Contact Dermatitis [description not available] | 0 | 4.35 | 17 | 0 |
| Infection, Postoperative Wound [description not available] | 0 | 12.91 | 47 | 20 |
| Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. | 0 | 4.35 | 17 | 0 |
| Complication, Postoperative [description not available] | 0 | 9.53 | 33 | 8 |
| Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 9.53 | 33 | 8 |
| Diathesis [description not available] | 0 | 2.31 | 1 | 0 |
| Allergy, Drug [description not available] | 0 | 2.52 | 2 | 0 |
| Drug Hypersensitivity Immunologically mediated adverse reactions to medicinal substances used legally or illegally. | 0 | 2.52 | 2 | 0 |
| Surgical Incision [description not available] | 0 | 6.12 | 8 | 3 |
| Ache [description not available] | 0 | 5.87 | 6 | 4 |
| Dehiscence, Surgical Wound [description not available] | 0 | 11.38 | 26 | 12 |
| Hematoma A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue. | 0 | 4.35 | 4 | 1 |
| Keloid A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues. | 0 | 2.74 | 3 | 0 |
| Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 5.87 | 6 | 4 |
| Phimosis A condition in which the FORESKIN cannot be retracted to reveal the GLANS PENIS. It is due to tightness or narrowing of the foreskin opening. | 0 | 2.54 | 2 | 0 |
| Benign Neoplasms [description not available] | 0 | 2.41 | 1 | 0 |
| Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 2.41 | 1 | 0 |
| Exanthem [description not available] | 0 | 2.41 | 1 | 0 |
| Exanthema Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology. | 0 | 2.41 | 1 | 0 |
| Cerebrospinal Fluid Drainage [description not available] | 0 | 3.36 | 5 | 0 |
| Acute Post-operative Pain [description not available] | 0 | 6.89 | 5 | 3 |
| Pain, Postoperative Pain during the period after surgery. | 0 | 6.89 | 5 | 3 |
| Contact Dermatitis [description not available] | 0 | 3.57 | 7 | 0 |
| Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms. | 0 | 3.57 | 7 | 0 |
| Bimalleolar Ankle Fractures [description not available] | 0 | 4.07 | 2 | 1 |
| Ankle Fractures Fractures of any of the bones of the ANKLE. | 0 | 4.07 | 2 | 1 |
| Cicatrization The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries. | 0 | 12.36 | 30 | 22 |
| Cicatrix The fibrous tissue that replaces normal tissue during the process of WOUND HEALING. | 0 | 12.36 | 30 | 22 |
| Foreign-Body Migration Migration of a foreign body from its original location to some other location in the body. | 0 | 3.17 | 1 | 0 |
| Acute Hypercapnic Respiratory Failure [description not available] | 0 | 2.21 | 1 | 0 |
| Respiratory Insufficiency Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) | 0 | 2.21 | 1 | 0 |
| Prurigo A name applied to several itchy skin eruptions of unknown cause. The characteristic course is the formation of a dome-shaped papule with a small transient vesicle on top, followed by crusting over or lichenification. (From Dorland, 27th ed) | 0 | 2.41 | 1 | 0 |
| Breast Diseases Pathological processes of the BREAST. | 0 | 4.42 | 2 | 2 |
| Hand Injuries General or unspecified injuries to the hand. | 0 | 2.25 | 1 | 0 |
| Injuries, Soft Tissue [description not available] | 0 | 2.25 | 1 | 0 |
| Lacerations Torn, ragged, mangled wounds. | 0 | 12.52 | 27 | 14 |
| Avulsed Tooth [description not available] | 0 | 2.52 | 2 | 0 |
| Lung Adenocarcinoma [description not available] | 0 | 2.25 | 1 | 0 |
| Carcinoma, Epidermoid [description not available] | 0 | 4.18 | 3 | 1 |
| Coin Lesion, Pulmonary [description not available] | 0 | 2.25 | 1 | 0 |
| Cancer of Lung [description not available] | 0 | 3.97 | 2 | 1 |
| Adenocarcinoma in Situ A lesion with cytological characteristics associated with invasive adenocarcinoma but the tumor cells are confined to the GLANDULAR EPITHELIAL CELLS of origin. Adenocarcinoma in situ of the CERVIX and the LUNG are the most common. | 0 | 2.25 | 1 | 0 |
| Multiple Pulmonary Nodules A number of small lung lesions characterized by small round masses of 2- to 3-mm in diameter. They are usually detected by chest CT scans (COMPUTED TOMOGRAPHY, X-RAY). Such nodules can be associated with metastases of malignancies inside or outside the lung, benign granulomas, or other lesions. | 0 | 2.25 | 1 | 0 |
| Adenocarcinoma of Lung A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer. | 0 | 2.25 | 1 | 0 |
| Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 4.18 | 3 | 1 |
| Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 3.97 | 2 | 1 |
| Arthritis, Degenerative [description not available] | 0 | 2.25 | 1 | 0 |
| Osteoarthritis A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 2.25 | 1 | 0 |
| Dermatitis Any inflammation of the skin. | 0 | 3.2 | 4 | 0 |
| Finger Injuries General or unspecified injuries involving the fingers. | 0 | 4.7 | 6 | 1 |
| Breast Cancer [description not available] | 0 | 3.05 | 4 | 0 |
| Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 3.05 | 4 | 0 |
| Blood Loss, Postoperative [description not available] | 0 | 5.62 | 3 | 2 |
| Dermatitis, Irritant A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms. | 0 | 2.31 | 1 | 0 |
| Cancer of Testis [description not available] | 0 | 2.31 | 1 | 0 |
| Testicular Neoplasms Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms. | 0 | 2.31 | 1 | 0 |
| Harelip [description not available] | 0 | 5.6 | 9 | 2 |
| Cleft Lip Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region. | 0 | 5.6 | 9 | 2 |
| Eye Injuries, Penetrating Deeply perforating or puncturing type intraocular injuries. | 0 | 6.2 | 4 | 1 |
| Intraocular Pressure The pressure of the fluids in the eye. | 0 | 2.96 | 4 | 0 |
| Cornea Injuries [description not available] | 0 | 2.49 | 2 | 0 |
| Corneal Perforation A puncture or hole through the CORNEAL STROMA resulting from various diseases or trauma. | 0 | 2.54 | 2 | 0 |
| Corneal Injuries Damage or trauma inflicted to the CORNEA by external means. | 0 | 2.49 | 2 | 0 |
| Infections, Staphylococcal [description not available] | 0 | 2.31 | 1 | 0 |
| Infections, Staphylococcal Skin [description not available] | 0 | 2.31 | 1 | 0 |
| Staphylococcal Infections Infections with bacteria of the genus STAPHYLOCOCCUS. | 0 | 2.31 | 1 | 0 |
| Staphylococcal Skin Infections Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS. | 0 | 2.31 | 1 | 0 |
| Innate Inflammatory Response [description not available] | 0 | 3.18 | 5 | 0 |
| Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 3.18 | 5 | 0 |
| Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 11.42 | 20 | 13 |
| Abscess Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection. | 0 | 2.15 | 1 | 0 |
| Adhesions, Tissue [description not available] | 0 | 4.58 | 5 | 1 |
| Cat Diseases Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used. | 0 | 2.17 | 1 | 0 |
| Thromboembolism, Venous [description not available] | 0 | 2.17 | 1 | 0 |
| Venous Thromboembolism Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream. | 0 | 2.17 | 1 | 0 |
| Colonic Diseases Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE). | 0 | 2.46 | 2 | 0 |
| Constriction, Pathological [description not available] | 0 | 2.17 | 1 | 0 |
| Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 3.85 | 11 | 0 |
| Anastomotic Leak Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis. | 0 | 2.82 | 3 | 0 |
| Constriction, Pathologic The condition of an anatomical structure's being constricted beyond normal dimensions. | 0 | 2.17 | 1 | 0 |
| Intestinal Obstruction Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL. | 0 | 2.17 | 1 | 0 |
| Carotid Artery Narrowing [description not available] | 0 | 2.21 | 1 | 0 |
| Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. | 0 | 2.21 | 1 | 0 |
| Carotid Stenosis Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) | 0 | 2.21 | 1 | 0 |
| Infection, Wound [description not available] | 0 | 5.59 | 6 | 0 |
| Recrudescence [description not available] | 0 | 7.83 | 12 | 2 |
| Esophageal Varices [description not available] | 0 | 8.98 | 26 | 1 |
| Hematochezia The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea. | 0 | 7.48 | 15 | 1 |
| Esophageal and Gastric Varices Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL). | 0 | 8.98 | 26 | 1 |
| Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. | 0 | 7.48 | 15 | 1 |
| Canine Diseases [description not available] | 0 | 3.56 | 1 | 1 |
| Gastric Volvulus [description not available] | 0 | 3.56 | 1 | 1 |
| Pancreatic Fistula Abnormal passage communicating with the PANCREAS. | 0 | 4.75 | 3 | 2 |
| Hypospadias A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA. | 0 | 4.85 | 2 | 1 |
| Angioma A vascular anomaly due to proliferation of blood or lymphatic vessels that forms a tumor-like mass. Vessels in the angioma may or may not be dilated. | 0 | 2.51 | 2 | 0 |
| Cancer of Lip [description not available] | 0 | 2.21 | 1 | 0 |
| Hemangioma A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000) | 0 | 2.51 | 2 | 0 |
| Fistula Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body. | 0 | 2.21 | 1 | 0 |
| Bleeding [description not available] | 0 | 3 | 4 | 0 |
| Cirrhosis, Liver [description not available] | 0 | 4.38 | 4 | 1 |
| Hemorrhage Bleeding or escape of blood from a vessel. | 0 | 3 | 4 | 0 |
| Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 4.38 | 4 | 1 |
| Fournier Disease [description not available] | 0 | 2.08 | 1 | 0 |
| Brain Abscess A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6) | 0 | 2.08 | 1 | 0 |
| Benign Neoplasms, Brain [description not available] | 0 | 3.36 | 2 | 0 |
| Astrocytoma, Grade IV [description not available] | 0 | 2.08 | 1 | 0 |
| Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 3.36 | 2 | 0 |
| Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.08 | 1 | 0 |
| Dermatitis Medicamentosa [description not available] | 0 | 2.1 | 1 | 0 |
| Bone Fractures [description not available] | 0 | 7.52 | 4 | 4 |
| Fractures, Bone Breaks in bones. | 0 | 7.52 | 4 | 4 |
| Cancer of Head [description not available] | 0 | 3.84 | 2 | 1 |
| Cancer of Skin [description not available] | 0 | 4.16 | 3 | 1 |
| Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 3.84 | 2 | 1 |
| Skin Neoplasms Tumors or cancer of the SKIN. | 0 | 4.16 | 3 | 1 |
| Chronic Liver Failure [description not available] | 0 | 2.1 | 1 | 0 |
| End Stage Liver Disease Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed. | 0 | 2.1 | 1 | 0 |
| Complications, Labor [description not available] | 0 | 9.71 | 9 | 9 |
| Bone Loss, Osteoclastic [description not available] | 0 | 2.1 | 1 | 0 |
| Periostitis Inflammation of the periosteum. The condition is generally chronic, and is marked by tenderness and swelling of the bone and an aching pain. Acute periostitis is due to infection, is characterized by diffuse suppuration, severe pain, and constitutional symptoms, and usually results in necrosis. (Dorland, 27th ed) | 0 | 2.1 | 1 | 0 |
| Injuries, Neck [description not available] | 0 | 2.1 | 1 | 0 |
| Facial Injuries General or unspecified injuries to the soft tissue or bony portions of the face. | 0 | 5.82 | 4 | 2 |
| Allergic Reaction [description not available] | 0 | 2.1 | 1 | 0 |
| Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. | 0 | 2.1 | 1 | 0 |
| Cutaneous Fistula An abnormal passage or communication leading from an internal organ to the surface of the body. | 0 | 4.4 | 1 | 1 |
| Urethral Diseases Pathological processes involving the URETHRA. | 0 | 4.4 | 1 | 1 |
| Urinary Fistula An abnormal passage in any part of the URINARY TRACT between itself or with other organs. | 0 | 4.4 | 1 | 1 |
| Abnormality, Heart [description not available] | 0 | 3.03 | 1 | 0 |
| Heart Defects, Congenital Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life. | 0 | 3.03 | 1 | 0 |
| Cleft Palate, Isolated [description not available] | 0 | 3.85 | 2 | 1 |
| Cleft Palate Congenital fissure of the soft and/or hard palate, due to faulty fusion. | 0 | 3.85 | 2 | 1 |
| Cancer of Pancreas [description not available] | 0 | 2.11 | 1 | 0 |
| Local Neoplasm Recurrence [description not available] | 0 | 2.11 | 1 | 0 |
| Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 2.11 | 1 | 0 |
| Rupture Forcible or traumatic tear or break of an organ or other soft part of the body. | 0 | 2.46 | 2 | 0 |
| Vascular Injuries [description not available] | 0 | 2.11 | 1 | 0 |
| Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.49 | 2 | 0 |
| Embolism, Pulmonary [description not available] | 0 | 5.23 | 6 | 0 |
| Acute Disease Disease having a short and relatively severe course. | 0 | 2.13 | 1 | 0 |
| Pulmonary Embolism Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS. | 0 | 5.23 | 6 | 0 |
| Ear Diseases Pathological processes of the ear, the hearing, and the equilibrium system of the body. | 0 | 2.15 | 1 | 0 |
| Infant, Newborn, Diseases Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. | 0 | 2.15 | 1 | 0 |
| Dermatoses [description not available] | 0 | 2.13 | 1 | 0 |
| Burns Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like. | 0 | 2.13 | 1 | 0 |
| Skin Diseases Diseases involving the DERMIS or EPIDERMIS. | 0 | 2.13 | 1 | 0 |
| Leg Dermatoses A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed) | 0 | 2.13 | 1 | 0 |
| Catheter-Associated Infections [description not available] | 0 | 9.76 | 9 | 9 |
| Complication, Intraoperative [description not available] | 0 | 3.88 | 2 | 1 |
| Pneumothorax, Primary Spontaneous [description not available] | 0 | 3.51 | 1 | 1 |
| Pneumothorax An accumulation of air or gas in the PLEURAL CAVITY, which may occur spontaneously or as a result of trauma or a pathological process. The gas may also be introduced deliberately during PNEUMOTHORAX, ARTIFICIAL. | 0 | 3.51 | 1 | 1 |
| Nail Diseases Diseases of the nail plate and tissues surrounding it. The concept is limited to primates. | 0 | 3.12 | 1 | 0 |
| Delayed Hypersensitivity [description not available] | 0 | 2.15 | 1 | 0 |
| Infection [description not available] | 0 | 2.15 | 1 | 0 |
| Injuries, Knee [description not available] | 0 | 2.15 | 1 | 0 |
| Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. | 0 | 2.15 | 1 | 0 |
| Knee Injuries Injuries to the knee or the knee joint. | 0 | 2.15 | 1 | 0 |
| Seroma Tumor-like sterile accumulation of serum in a tissue, organ, or cavity. It results from a tissue insult and is the product of tissue inflammation. It most commonly occurs following MASTECTOMY. | 0 | 2.15 | 1 | 0 |
| Abdominal Hernia [description not available] | 0 | 2.15 | 1 | 0 |
| Foreign-Body Reaction Chronic inflammation and granuloma formation around irritating foreign bodies. | 0 | 3.85 | 4 | 0 |
| Injuries Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used. | 0 | 9.49 | 13 | 7 |
| Wounds and Injuries Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. | 0 | 9.49 | 13 | 7 |
| Cystic Hygroma Colli [description not available] | 0 | 2.04 | 1 | 0 |
| Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. | 0 | 2.04 | 1 | 0 |
| Hypomelanosis [description not available] | 0 | 3.43 | 1 | 1 |
| Hypopigmentation A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections. | 0 | 3.43 | 1 | 1 |
| Cardiac Rupture, Post-Infarction [description not available] | 0 | 2.05 | 1 | 0 |
| Atrophy Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 2.05 | 1 | 0 |
| Bleb [description not available] | 0 | 2.05 | 1 | 0 |
| Corneal Diseases Diseases of the cornea. | 0 | 2.43 | 2 | 0 |
| Chronic Primary Open Angle Glaucoma [description not available] | 0 | 2.05 | 1 | 0 |
| Rupture, Spontaneous Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force. | 0 | 2.43 | 2 | 0 |
| Glaucoma, Open-Angle Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris. | 0 | 2.05 | 1 | 0 |
| Fibroid [description not available] | 0 | 2.05 | 1 | 0 |
| Blood Loss, Surgical Loss of blood during a surgical procedure. | 0 | 2.05 | 1 | 0 |
| Leiomyoma A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues. | 0 | 2.05 | 1 | 0 |
| Premature Rupture of Fetal Membranes [description not available] | 0 | 2.05 | 1 | 0 |
| Fetal Membranes, Premature Rupture Spontaneous tearing of the membranes surrounding the FETUS any time before the onset of OBSTETRIC LABOR. Preterm PROM is membrane rupture before 37 weeks of GESTATION. | 0 | 2.05 | 1 | 0 |
| Ear Deformities, Acquired Distortion or disfigurement of the ear caused by disease or injury after birth. | 0 | 2.05 | 1 | 0 |
| Angiogranuloma [description not available] | 0 | 2.05 | 1 | 0 |
| Osteoarthritis of Knee [description not available] | 0 | 2.05 | 1 | 0 |
| Osteoarthritis, Knee Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019) | 0 | 2.05 | 1 | 0 |
| Weight Gain Increase in BODY WEIGHT over existing weight. | 0 | 2.05 | 1 | 0 |
| Disease, Pulmonary [description not available] | 0 | 2.06 | 1 | 0 |
| Lung Diseases Pathological processes involving any part of the LUNG. | 0 | 2.06 | 1 | 0 |
| Arrhythmia [description not available] | 0 | 3.83 | 2 | 1 |
| Arrhythmias, Cardiac Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. | 0 | 3.83 | 2 | 1 |
| Bites, Human Bites inflicted by humans. | 0 | 2.06 | 1 | 0 |
| Retinal Pigment Epithelial Detachment [description not available] | 0 | 2.44 | 2 | 0 |
| Retinal Detachment Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12). | 0 | 2.44 | 2 | 0 |
| Eyelid Diseases Diseases involving the EYELIDS. | 0 | 2.06 | 1 | 0 |
| Chronic Illness [description not available] | 0 | 3.39 | 2 | 0 |
| Middle Ear Inflammation [description not available] | 0 | 2.06 | 1 | 0 |
| Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 3.39 | 2 | 0 |
| Otitis Media Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE. | 0 | 2.06 | 1 | 0 |
| Hepatitis B Virus Infection [description not available] | 0 | 2.06 | 1 | 0 |
| Hepatitis B INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. | 0 | 2.06 | 1 | 0 |
| Cystic Kidney Diseases [description not available] | 0 | 2.06 | 1 | 0 |
| Kidney Diseases, Cystic A heterogeneous group of hereditary and acquired disorders in which the KIDNEY contains one or more CYSTS unilaterally or bilaterally (KIDNEY, CYSTIC). | 0 | 2.06 | 1 | 0 |
| Parotid Diseases Diseases involving the PAROTID GLAND. | 0 | 2.06 | 1 | 0 |
| Salivary Gland Fistula A fistula between a salivary duct or gland and the cutaneous surface of the oral cavity. | 0 | 2.06 | 1 | 0 |
| Cancer of Ovary [description not available] | 0 | 2.07 | 1 | 0 |
| Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 2.07 | 1 | 0 |
| Fasciitis, Necrotizing A fulminating bacterial infection of the deep layers of the skin and FASCIA. It can be caused by many different organisms, with STREPTOCOCCUS PYOGENES being the most common. | 0 | 2.99 | 1 | 0 |
| Cellulitis, Orbital [description not available] | 0 | 2.99 | 1 | 0 |
| Group A Strep Infection [description not available] | 0 | 2.99 | 1 | 0 |
| Bacterial Eye Infections [description not available] | 0 | 2.99 | 1 | 0 |
| Streptococcal Infections Infections with bacteria of the genus STREPTOCOCCUS. | 0 | 2.99 | 1 | 0 |
| Pyrexia [description not available] | 0 | 2.07 | 1 | 0 |
| Tachyarrhythmia [description not available] | 0 | 2.07 | 1 | 0 |
| Fever An abnormal elevation of body temperature, usually as a result of a pathologic process. | 0 | 2.07 | 1 | 0 |
| Tachycardia Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia. | 0 | 2.07 | 1 | 0 |
| Hospital-Acquired Condition [description not available] | 0 | 2.07 | 1 | 0 |
| Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2.44 | 2 | 0 |
| Wounds, Stab Penetrating wounds caused by a pointed object. | 0 | 3.83 | 2 | 1 |
| Inguinal Hernia [description not available] | 0 | 8.12 | 7 | 5 |
| Hernia, Inguinal An abdominal hernia with an external bulge in the GROIN region. It can be classified by the location of herniation. Indirect inguinal hernias occur through the internal inguinal ring. Direct inguinal hernias occur through defects in the ABDOMINAL WALL (transversalis fascia) in Hesselbach's triangle. The former type is commonly seen in children and young adults; the latter in adults. | 0 | 8.12 | 7 | 5 |
| Kidney Stones [description not available] | 0 | 2.01 | 1 | 0 |
| Kidney Calculi Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE. | 0 | 2.01 | 1 | 0 |
| Emergencies Situations or conditions requiring immediate intervention to avoid serious adverse results. | 0 | 2.02 | 1 | 0 |
| Fractures, Comminuted A fracture in which the bone is splintered or crushed into a number of pieces. | 0 | 2.02 | 1 | 0 |
| Segond Fracture [description not available] | 0 | 2.02 | 1 | 0 |
| Tibial Fractures Fractures of the TIBIA. | 0 | 2.02 | 1 | 0 |
| Central Nervous System Disease [description not available] | 0 | 2.02 | 1 | 0 |
| Craniocerebral Injuries [description not available] | 0 | 2.02 | 1 | 0 |
| Central Nervous System Diseases Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord. | 0 | 2.02 | 1 | 0 |
| Craniocerebral Trauma Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage. | 0 | 2.02 | 1 | 0 |
| Embolus [description not available] | 0 | 2.02 | 1 | 0 |
| Embolism Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream. | 0 | 2.02 | 1 | 0 |
| Infectious Endophthalmitis Infectious condition of the internal eye. | 0 | 2.02 | 1 | 0 |
| Endophthalmitis Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection. | 0 | 2.02 | 1 | 0 |
| Nearsightedness [description not available] | 0 | 2.02 | 1 | 0 |
| Envenomation, Snakebite [description not available] | 0 | 2.02 | 1 | 0 |
| Myopia A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness. | 0 | 2.02 | 1 | 0 |
| Tooth Fractures Break or rupture of a tooth or tooth root. | 0 | 2.03 | 1 | 0 |
| Thyroid Diseases Pathological processes involving the THYROID GLAND. | 0 | 3.42 | 1 | 1 |
| Carcinoma, Basal Cell, Pigmented [description not available] | 0 | 3.42 | 1 | 1 |
| Facial Neoplasms New abnormal growth of tissue in the FACE. | 0 | 3.42 | 1 | 1 |
| Carcinoma, Basal Cell A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471) | 0 | 3.42 | 1 | 1 |
| Amblyopia, Developmental [description not available] | 0 | 2.04 | 1 | 0 |
| Amblyopia A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications. | 0 | 2.04 | 1 | 0 |
| Wounds, Penetrating Wounds caused by objects penetrating the skin. | 0 | 4.86 | 4 | 2 |
| Pocket, Periodontal [description not available] | 0 | 3.38 | 1 | 1 |
| Pericementitis [description not available] | 0 | 3.38 | 1 | 1 |
| Hemorrhage, Gingival [description not available] | 0 | 3.38 | 1 | 1 |
| Gingival Hemorrhage The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY. | 0 | 3.38 | 1 | 1 |
| Periodontal Pocket An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption. | 0 | 3.38 | 1 | 1 |
| Periodontitis Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) | 0 | 3.38 | 1 | 1 |
| Aphthae [description not available] | 0 | 5.67 | 5 | 4 |
| Stomatitis, Aphthous A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742) | 0 | 5.67 | 5 | 4 |
| Concomitant Strabismus [description not available] | 0 | 2 | 1 | 0 |
| Strabismus Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641) | 0 | 2 | 1 | 0 |
| Varices [description not available] | 0 | 3.39 | 1 | 1 |
| Varicose Veins Enlarged and tortuous VEINS. | 0 | 3.39 | 1 | 1 |
| Mouth Ulcer [description not available] | 0 | 3.39 | 1 | 1 |
| Gingivostomatitis, Herpetic [description not available] | 0 | 3.39 | 1 | 1 |
| Stomatitis, Herpetic Stomatitis caused by Herpesvirus hominis. It usually occurs as acute herpetic stomatitis (or gingivostomatitis), an oral manifestation of primary herpes simplex seen primarily in children and adolescents. | 0 | 3.39 | 1 | 1 |
| Oral Ulcer A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842) | 0 | 3.39 | 1 | 1 |
| Injuries, Needlestick [description not available] | 0 | 3.39 | 1 | 1 |