Proteins > Gastrin/cholecystokinin type B receptor
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Gastrin/cholecystokinin type B receptor
A cholecystokinin receptor 2 that is encoded in the genome of rat. [OMA:P30553, PRO:DNx]
Synonyms
CCK-B receptor;
CCK-BR;
Cholecystokinin-2 receptor;
CCK2-R
Research
Bioassay Publications (21)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
Compounds (26)
Drugs with Potency Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| lithium chloride | Rattus norvegicus (Norway rat) | Potency | 710.0000 | 1 | 0 |
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| androstenedione | Rattus norvegicus (Norway rat) | Km | 0.0575 | 1 | 1 |
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.Journal of medicinal chemistry, , Oct-05, Volume: 43, Issue:20, 2000
Synthesis and biological properties of new constrained CCK-B antagonists: discrimination of two affinity states of the CCK-B receptor on transfected CHO cells.Journal of medicinal chemistry, , Nov-21, Volume: 40, Issue:24, 1997
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.Journal of medicinal chemistry, , Oct-05, Volume: 43, Issue:20, 2000
Cholecystokinin antagonists. Synthesis and biological evaluation of 3-substituted benzolactams.Journal of medicinal chemistry, , Volume: 32, Issue:8, 1989
Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.Journal of medicinal chemistry, , Oct-05, Volume: 43, Issue:20, 2000
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.Journal of medicinal chemistry, , Feb-28, Volume: 40, Issue:5, 1997
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.Journal of medicinal chemistry, , Oct-05, Volume: 43, Issue:20, 2000
Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid.Bioorganic & medicinal chemistry letters, , Jun-02, Volume: 8, Issue:11, 1998
Synthesis and biological properties of new constrained CCK-B antagonists: discrimination of two affinity states of the CCK-B receptor on transfected CHO cells.Journal of medicinal chemistry, , Nov-21, Volume: 40, Issue:24, 1997
Synthesis and biological characterisation of [3H]BBL454, a new CCK2 selective radiolabelled agonist displaying original pharmacological properties.Bioorganic & medicinal chemistry letters, , Jan-19, Volume: 14, Issue:2, 2004
Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.Journal of medicinal chemistry, , Oct-05, Volume: 43, Issue:20, 2000
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.Journal of medicinal chemistry, , Feb-28, Volume: 40, Issue:5, 1997