chlorzoxazone has been researched along with Sensitivity and Specificity in 10 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A reproducible, rapid and sensitive method has been developed for the assay of chlorzoxazone (CHL), paracetamol (PCM) and aceclofenac (ACE) in their combined solid dosage forms using packed-column supercritical fluid chromatography (SFC)." | 1.38 | Development and validation of packed column supercritical fluid chromatographic technique for quantification of chlorzoxazone, paracetamol and aceclofenac in their individual and combined dosage forms. ( Desai, PP; Mehta, PJ; Patel, NR; Sherikar, OD, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Shaikh, KA | 1 |
| Devkhile, AB | 1 |
| Wu, JY | 1 |
| Yue, J | 1 |
| Feng, YQ | 1 |
| Desai, PP | 1 |
| Patel, NR | 1 |
| Sherikar, OD | 1 |
| Mehta, PJ | 1 |
| Abdelaleem, EA | 1 |
| Abdelwahab, NS | 1 |
| Gandhimathi, M | 1 |
| Ravi, TK | 1 |
| Abraham, A | 1 |
| Thomas, R | 1 |
| Frye, RF | 1 |
| Stiff, DD | 1 |
| Eap, CB | 1 |
| Schnyder, C | 1 |
| Savary, L | 1 |
| Tanaka, E | 1 |
| Scott, RJ | 1 |
| Palmer, J | 1 |
| Lewis, IA | 1 |
| Pleasance, S | 1 |
10 other studies available for chlorzoxazone and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Simultaneous determination of aceclofenac, paracetamol, and chlorzoxazone by RP-HPLC in pharmaceutical dosage form.
Topics: Acetaminophen; Chlorzoxazone; Chromatography, High Pressure Liquid; Diclofenac; Reproducibility of R | 2008 |
Determination of brain cytochrome P450 2E1 activity in rat with the probe of chlorzoxazone by liquid chromatography-mass spectrometry.
Topics: Animals; Brain; Brain Chemistry; Calibration; Chlorzoxazone; Chromatography, Liquid; Cytochrome P-45 | 2011 |
Development and validation of packed column supercritical fluid chromatographic technique for quantification of chlorzoxazone, paracetamol and aceclofenac in their individual and combined dosage forms.
Topics: Acetaminophen; Carbon Dioxide; Chlorzoxazone; Chromatography, Supercritical Fluid; Diclofenac; Drug | 2012 |
Stability-indicating TLC-densitometric method for simultaneous determination of paracetamol and chlorzoxazone and their toxic impurities.
Topics: Acetaminophen; Aminophenols; Capsules; Chlorophenols; Chlorzoxazone; Chromatography, Thin Layer; Den | 2013 |
Simultaneous determination of aspirin and isosorbide 5-mononitrate in formulation by reversed phase high pressure liquid chromatography.
Topics: Aspirin; Chlorzoxazone; Chromatography, High Pressure Liquid; Isosorbide Dinitrate; Reference Standa | 2003 |
Determination of chlorzoxazone and 6-hydroxychlorzoxazone in human plasma and urine by high-performance liquid chromatography.
Topics: Chlorzoxazone; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sensitivity | 1996 |
Determination of chlorzoxazone and 6-hydroxychlorzoxazone in plasma by gas chromatography--mass spectrometry.
Topics: Acetamides; Chlorzoxazone; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Muscle Rela | 1998 |
Simultaneous determination of chlorzoxazone, indicator of CYP2E1, and its metabolite in human serum using a new reversed-phase chromatographic column of 2-microm porous microspherical silica-gel.
Topics: Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Humans; Male; Middle A | 1998 |
Determination of a 'GW cocktail' of cytochrome P450 probe substrates and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry.
Topics: Automation; Caffeine; Chlorzoxazone; Chromatography, Gas; Chromatography, High Pressure Liquid; Cyto | 1999 |