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ketoprofen and Sensitivity and Specificity

ketoprofen has been researched along with Sensitivity and Specificity in 40 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" Suitability of the new assay was assessed in comparison with 36 reported bioanalytical assays and the pharmacokinetic results obtained by the new method were compared to 11 reported studies in humans."1.37An LC-MS/MS procedure for the quantification of naproxen in human plasma: development, validation, comparison with other methods, and application to a pharmacokinetic study. ( Elsinghorst, PW; Holzgrabe, U; Kinzig, M; Rodamer, M; Sörgel, F, 2011)
"Methacrylic acid (MAA) has been known to be an inefficient functional monomer in preparation of MIP of an acid molecule."1.35Robust open tubular layer of S-ketoprofen imprinted polymer for chiral LC separation. ( Cheong, WJ; Zaidi, SA, 2008)
" Validation data and study sample data from patients dosed with either orally or topically administered ketoprofen were generated using both pcSFC and LC as the chromatographic methods to compare and contrast these analytical approaches."1.31Comparison of packed-column supercritical fluid chromatography--tandem mass spectrometry with liquid chromatography--tandem mass spectrometry for bioanalytical determination of (R)- and (S)-ketoprofen in human plasma following automated 96-well solid-phas ( Bailey, RE; Eichhold, TH; Hoke, SH; Pinkston, JD; Tanguay, SL, 2000)
"In 31 patients with symptoms of renal colic, treated with ketoprofen, unilateral obstruction was confirmed by intravenous urography."1.31Time-dependent changes of resistive index in acute renal obstruction during nonsteroidal drug administration. ( Buturovic-Ponikvar, J; Kmetec, A; Peskar-Babnik, D, 2002)
"Ketoprofen was detected in some milk samples, 10 to 120 minutes after administration, but all concentrations were below the limit of quantification."1.29Ketoprofen concentrations in plasma and milk after intravenous administration in dairy cattle. ( De Graves, FJ; Riddell, MG; Schumacher, J, 1996)
"Mefenamic acid (MA) is a nonsteroidal antiinflammatory analgesic agent widely used clinically."1.28Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma. ( Cheymol, G; Lebot, M; Poirier, JM, 1992)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (27.50)18.2507
2000's24 (60.00)29.6817
2010's5 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Li, H1
Sun, J1
Sui, X1
Liu, J1
Yan, Z1
Liu, X1
Sun, Y1
He, Z1
Bu, D1
Zhuang, HS1
Yang, GX1
Zaidi, SA1
Cheong, WJ1
Elsayed, MM1
Vierl, U1
Cevc, G1
Lee, HW1
Ji, HY1
Sohn, DH1
Kim, SM1
Lee, YB1
Lee, HS1
Dowling, G1
Gallo, P1
Fabbrocino, S1
Serpe, L1
Regan, L1
Botello, I1
Borrull, F1
Aguilar, C1
Calull, M1
Elsinghorst, PW1
Kinzig, M1
Rodamer, M1
Holzgrabe, U1
Sörgel, F1
Wei, ZH1
Wu, X1
Zhang, B1
Li, R1
Huang, YP1
Liu, ZS1
Gotti, R1
Fiori, J1
Calleri, E1
Temporini, C1
Lubda, D1
Massolini, G1
Dykes, S1
Fancy, SA1
Perkins, GL1
Pullen, FS1
He, YY1
Ramirez, DC1
Detweiler, CD1
Mason, RP1
Chignell, CF1
López-Abad, R1
Paniagua, MJ1
Botey, E1
Gaig, P1
Rodriguez, P1
Richart, C1
Bempong, DK1
Bhattacharyya, L1
Chawla, S1
Ghosh, S1
Sihorkar, V1
Nellore, R1
Kumar, TR1
Srinivas, NR1
Guo, Z1
Wang, H1
Zhang, Y1
Pickl, KE1
Magnes, C1
Bodenlenz, M1
Pieber, TR1
Sinner, FM1
Suárez, B1
Simonet, BM1
Cárdenas, S1
Valcárcel, M1
Lin, PC1
Tseng, MC1
Su, AK1
Chen, YJ1
Lin, CC1
Zhuang, Y1
Song, H1
Blanco, M1
Alcalá, M1
Bautista, M1
Dubois-Presle, N1
Lapicque, F1
Maurice, MH1
Fournel-Gigleux, S1
Magdalou, J1
Abiteboul, M1
Siest, G1
Netter, P1
Grubb, NG1
Rudy, DW1
Hall, SD1
De Graves, FJ1
Riddell, MG1
Schumacher, J1
Lovlin, R1
Vakily, M1
Jamali, F1
Boisvert, J1
Caillé, G1
McGilveray, IJ1
Qureshi, SA1
Jourdan, D1
Ardid, D1
Bardin, L1
Bardin, M1
Neuzeret, D1
Lanphouthacoul, L1
Eschalier, A1
Friedberg, M1
Shihabi, ZK1
Way, BA1
Wilhite, TR1
Smith, CH1
Landt, M1
Ameyibor, E1
Stewart, JT1
Proniuk, S1
Lerkpulsawad, S1
Blanchard, J1
de Jalón, EG1
Josa, M1
Campanero, MA1
Santoyo, S1
Ygartua, P1
Baeyens, WR1
Van der Weken, G1
Haustraete, J1
Aboul-Enein, HY1
Corveleyn, S1
Remon, JP1
García-Campaña, AM1
Deprez, P1
Hoke, SH1
Pinkston, JD1
Bailey, RE1
Tanguay, SL1
Eichhold, TH1
Abdel-Hamid, ME1
Novotny, L1
Hamza, H1
Coran, SA1
Giannellini, V1
Furlanetto, S1
Bambagiotti-Alberti, M1
Pinzauti, S1
Péhourcq, F1
Jarry, C1
Bannwarth, B1
Kmetec, A1
Peskar-Babnik, D1
Buturovic-Ponikvar, J1
Poirier, JM1
Lebot, M1
Cheymol, G1

Other Studies

40 other studies available for ketoprofen and Sensitivity and Specificity

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metab

2009
A sensitive enzyme-linked immunosorbent assay amplified by biotin-streptavidin system for detecting non-steroidal anti-inflammatory drug ketoprofen.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2014, Volume: 49, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aquaculture; Biotin; Carps; Cross Reactions; Enzym

2014
Robust open tubular layer of S-ketoprofen imprinted polymer for chiral LC separation.
    Journal of separation science, 2008, Volume: 31, Issue:16-17

    Topics: Chromatography, Liquid; Ketoprofen; Methacrylates; Molecular Imprinting; Particle Size; Polymers; Re

2008
Accurate potentiometric determination of lipid membrane-water partition coefficients and apparent dissociation constants of ionizable drugs: electrostatic corrections.
    Pharmaceutical research, 2009, Volume: 26, Issue:6

    Topics: Bupivacaine; Diclofenac; Ions; Ketoprofen; Membrane Lipids; Naphthalenes; Osmolar Concentration; Pha

2009
Liquid chromatography-tandem mass spectrometry method of loxoprofen in human plasma.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:7

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Ketoprofen; Linear Models; Male; Pheny

2009
Determination of ibuprofen, ketoprofen, diclofenac and phenylbutazone in bovine milk by gas chromatography-tandem mass spectrometry.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2008, Volume: 25, Issue:12

    Topics: Animals; Cattle; Diclofenac; Drug Residues; Food Analysis; Food Contamination; Gas Chromatography-Ma

2008
Electrokinetic supercharging focusing in capillary zone electrophoresis of weakly ionizable analytes in environmental and biological samples.
    Electrophoresis, 2010, Volume: 31, Issue:17

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Fenoprofen; Humans;

2010
An LC-MS/MS procedure for the quantification of naproxen in human plasma: development, validation, comparison with other methods, and application to a pharmacokinetic study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Jun-01, Volume: 879, Issue:19

    Topics: Chromatography, Liquid; Drug Stability; Humans; Ketoprofen; Linear Models; Naproxen; Reproducibility

2011
Coatings of one monomer molecularly imprinted polymers for open tubular capillary electrochromatography.
    Journal of chromatography. A, 2011, Sep-16, Volume: 1218, Issue:37

    Topics: Amlodipine; Capillary Electrochromatography; Hydrogen-Ion Concentration; Ketoprofen; Microscopy, Ele

2011
Chiral capillary liquid chromatography based on penicillin G acylase immobilized on monolithic epoxy silica column.
    Journal of chromatography. A, 2012, Apr-20, Volume: 1234

    Topics: Chromatography, Liquid; Enzymes, Immobilized; Ketoprofen; Linear Models; Penicillin Amidase; Reprodu

2012
The automation of a commercial Fourier transform mass spectrometer to provide a quick and robust method for determining exact mass for the synthetic chemist.
    European journal of mass spectrometry (Chichester, England), 2003, Volume: 9, Issue:2

    Topics: Automation; Fourier Analysis; Ketoprofen; Mass Spectrometry; Molecular Weight; Reserpine; Sensitivit

2003
UVA-ketoprofen-induced hemoglobin radicals detected by immuno-spin trapping.
    Photochemistry and photobiology, 2003, Volume: 77, Issue:6

    Topics: Catalase; Erythrocytes; Free Radicals; Hemoglobins; Hemolysis; Humans; Hydrogen Peroxide; Immunoassa

2003
Topical dexketoprofen as a cause of photocontact dermatitis.
    Journal of investigational allergology & clinical immunology, 2004, Volume: 14, Issue:3

    Topics: Administration, Topical; Aged; Dermatitis, Allergic Contact; Dermatitis, Photoallergic; Female; Foll

2004
Development and validation of a stability-indicating high-performance liquid chromatographic assay for ketoprofen topical penetrating gel.
    Journal of chromatography. A, 2005, May-06, Volume: 1073, Issue:1-2

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liqu

2005
High-performance liquid chromatography method development and validation for simultaneous determination of five model compounds, antipyrine, metoprolol, ketoprofen, furosemide and phenol red, as a tool for the standardization of rat in situ intestinal per
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:4

    Topics: Animals; Antipyrine; Chromatography, High Pressure Liquid; Drug Stability; Furosemide; Intestinal Ab

2006
Chiral separation of ketoprofen on an achiral C8 column by HPLC using norvancomycin as chiral mobile phase additives.
    Journal of pharmaceutical and biomedical analysis, 2006, Apr-11, Volume: 41, Issue:1

    Topics: Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentra

2006
Rapid online-SPE-MS/MS method for ketoprofen determination in dermal interstitial fluid samples from rats obtained by microdialysis or open-flow microperfusion.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, May-01, Volume: 850, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Extracellular Fluid; Ketoprofen; Microdialysis; Ra

2007
Determination of non-steroidal anti-inflammatory drugs in urine by combining an immobilized carboxylated carbon nanotubes minicolumn for solid-phase extraction with capillary electrophoresis-mass spectrometry.
    Journal of chromatography. A, 2007, Aug-03, Volume: 1159, Issue:1-2

    Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Electrophoresis, Capillary; H

2007
Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.
    Analytical chemistry, 2007, May-01, Volume: 79, Issue:9

    Topics: Flufenamic Acid; Humans; Ketoprofen; Macrolides; Magnetics; Mannose; Mefenamic Acid; Molecular Struc

2007
Sensitive determination of ketoprofen using flow injection with chemiluminescence detection.
    Journal of pharmaceutical and biomedical analysis, 2007, Jul-27, Volume: 44, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Female; Flow Injection Analysis; Humans; Ketoprof

2007
Pharmaceutical gel analysis by NIR spectroscopy. Determination of the active principle and low concentration of preservatives.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Apr-23, Volume: 33, Issue:4-5

    Topics: Calibration; Chemistry, Pharmaceutical; Hydrogels; Ketoprofen; Parabens; Pharmaceutical Preparations

2008
Stereoselective esterase activity of human serum albumin toward ketoprofen glucuronide.
    Molecular pharmacology, 1995, Volume: 47, Issue:3

    Topics: Binding Sites; Circular Dichroism; Esterases; Humans; Hydrolysis; Ketoprofen; Kinetics; Sensitivity

1995
Stereoselective high-performance liquid chromatographic analysis of ketoprofen and its acyl glucuronides in chronic renal insufficiency.
    Journal of chromatography. B, Biomedical applications, 1996, Apr-12, Volume: 678, Issue:2

    Topics: Acylation; Chromatography, High Pressure Liquid; Dialysis Solutions; Glucuronates; Humans; Hydrogen-

1996
Ketoprofen concentrations in plasma and milk after intravenous administration in dairy cattle.
    American journal of veterinary research, 1996, Volume: 57, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Chromatography, High Pressure Liquid; Fema

1996
Rapid, sensitive and direct chiral high-performance liquid chromatographic method for ketoprofen enantiomers.
    Journal of chromatography. B, Biomedical applications, 1996, Apr-26, Volume: 679, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cyclooxygena

1996
Quantification of ketoprofen enantiomers in human plasma based on solid-phase extraction and enantioselective column chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Mar-07, Volume: 690, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Humans; Ketoprofen; R

1997
A new automated method of pain scoring in the formalin test in rats.
    Pain, 1997, Volume: 71, Issue:3

    Topics: Analgesics, Opioid; Animals; Automation; Image Processing, Computer-Assisted; Ketoprofen; Male; Morp

1997
Ketoprofen analysis in serum by capillary electrophoresis.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jul-18, Volume: 695, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Electrophoresis, Capi

1997
Measurement of plasma ibuprofen by gas chromatography-mass spectrometry.
    Journal of clinical laboratory analysis, 1997, Volume: 11, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Monitoring; Fenoprofen; Gas Chromatograp

1997
HPLC determination of ketoprofen enantiomers in human serum using a nonporous octadecylsilane 1.5 microns column with hydroxypropyl beta-cyclodextrin as mobile phase additive.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Chro

1998
A simplified and rapid high-performance liquid chromatographic assay for ketoprofen in isopropyl myristate.
    Journal of chromatographic science, 1998, Volume: 36, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ketoprofen; Myristate

1998
Determination by high-performance liquid chromatography of ketoprofen in vitro in rat skin permeation samples.
    Journal of chromatography. A, 2000, Feb-18, Volume: 870, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ketoprofen;

2000
Application of the restricted-access precolumn packing material alkyl-diol silica in a column-switching system for the determination of ketoprofen enantiomers in horse plasma.
    Journal of chromatography. A, 2000, Feb-25, Volume: 871, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Horses; Keto

2000
Comparison of packed-column supercritical fluid chromatography--tandem mass spectrometry with liquid chromatography--tandem mass spectrometry for bioanalytical determination of (R)- and (S)-ketoprofen in human plasma following automated 96-well solid-phas
    Analytical chemistry, 2000, Sep-01, Volume: 72, Issue:17

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Humans; Ketoprofen; Male; Mass Spec

2000
Determination of diclofenac sodium, flufenamic acid, indomethacin and ketoprofen by LC-APCI-MS.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 24, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chromatography, High Pressure Liquid; Diclofenac;

2001
Improving gas chromatographic determination of residual solvents in pharmaceuticals by the combined use of headspace solid-phase microextraction and isotopic dilution.
    Journal of chromatography. A, 2001, Apr-27, Volume: 915, Issue:1-2

    Topics: Calibration; Isotopes; Ketoprofen; Reproducibility of Results; Sensitivity and Specificity; Solvents

2001
Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase.
    Biomedical chromatography : BMC, 2001, Volume: 15, Issue:3

    Topics: Buffers; Chromatography, High Pressure Liquid; Drug Stability; Flurbiprofen; Furans; Glycopeptides;

2001
Time-dependent changes of resistive index in acute renal obstruction during nonsteroidal drug administration.
    BJU international, 2002, Volume: 89, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colic; Female; Huma

2002
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:4

    Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin;

1992