Page last updated: 2024-08-24

atorvastatin and Sensitivity and Specificity

atorvastatin has been researched along with Sensitivity and Specificity in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.69)18.2507
2000's36 (61.02)29.6817
2010's21 (35.59)24.3611
2020's1 (1.69)2.80

Authors

AuthorsStudies
Cestari, RN; de Oliveira, RDR; Lanchote, VL; Marques, MP; Rocha, A1
Apola, A; Kwiecień, A; Maślanka, A; Opoka, W; Stolarczyk, M1
Badr, KA; Rezk, MR1
Alves Saldanha, S; Buclin, T; Cavassini, M; Courlet, P; Csajka, C; Decosterd, LA; Desfontaine, V; Marzolini, C; Spaggiari, D1
Nasr, JJ; Shalan, S1
D'Ettorre, A; Macchia, A; Mariani, J; Romero, M; Tognoni, G1
Farkas, Z; Gácser, A; Grózer, Z; Márki-Zay, J; Nagy, K; Pfeiffer, I; Szenzenstein, J; Vágvölgyi, C1
Cheng, WP; Lo, HM; Shyu, KG; Wang, BW1
Covassin, N; Friedman, PA; Kara, T; Koestler, C; Lerman, A; Lopez-Jimenez, F; Ruzek, L; Singh, P; Somers, VK; Soucek, F; Suleiman, M1
Deng, H; Hou, Z; Ju, L; Li, Y; Wang, L; Wang, Y; Xie, J; Zhang, Y; Zhang, Z1
Asada, MN; Mimura, H; Nemoto, T1
Kadav, AA; Vora, DN1
Buss, S; Filusch, A; Hansen, A; Hardt, S; Katus, HA; Kuecherer, HF1
Momohara, C; Nonomura, N; Okuyama, A; Tsujihata, M; Tsujimura, A; Yoshioka, I1
Antonioli, L; Blandizzi, C; Colucci, R; Daghini, E; Del Tacca, M; Duranti, E; Fornai, M; Ghisu, N; Giannarelli, C; Taddei, S; Versari, D; Virdis, A1
Bláha, M; Bláha, V; Nováková, L; Sadílek, P; Satínský, D; Solich, P; Solichová, D; Vlcková, H1
Chiu, B; Fenster, A; Krasinski, A; Parraga, G; Spence, JD1
Abdul-Salam, VB; Boyle, JJ; Davies, AH; Edwards, RJ; Gillard, JH; Krishnan, U; Owen, DR; Ramrakha, P; Shalhoub, J; Tang, TY; Wilkins, MR1
Inamadugu, JK; Karra, VK; Mullangi, R; Pilli, NR; Rao, JV; Vaidya, JR1
Allard, JP; Arendt, BM1
Ahmad, L; Iqbal, Z; Khan, A; Khan, MI; Nasir, F; Nazir, S; Shah, Y1
Braunwald, E; Cannon, CP; Morrow, DA; Nazer, B; Ray, KK; Scirica, B; Sloan, S1
Åsberg, A; Bogsrud, MP; Hermann, M; Retterstøl, K; Skottheim, IB1
Darwish, HW; El-Zeiny, BA; Hassan, SA; Salem, MY1
Gajula, R; Inamadugu, JK; Mullangi, R; Pilli, NR; Ponneri, V; Ravi, VB1
Ali, J; Baboota, S; Goel, A; Gupta, A; Gupta, RS; Sahni, JK; Semwal, VP; Srinivas, KS1
Alawi, M; Arafat, T; Awwad, AA; Yacoub, M1
Chapman, MJ; Doucet, C; Gonbert, S; Laouenan, H; Malinsky, S; Sposito, AC; Thillet, J1
Ashby, DT; Conditt, G; Dangas, G; Hirose, M1
Metcalfe, CD; Miao, XS1
Baykan, M; Calapoğlu, M; Erdöl, C; Orem, A; Orem, C; Uydu, HA1
Coupal, L; Grover, SA; Ho, V; Lavoie, F; Pilote, L; Zowall, H1
Brandle, M; Davidson, MB; Herman, WH; Lorber, B; Schriger, DL1
Düsing, R; Klose, G; Szucs, TD1
Chen, YF; Hwang, YS; Lin, CC; Lu, YH; Tsai, WC1
Fitchett, DH; Goodman, S; Langer, A; Leiter, LA; Tardif, JC1
Christensen, H; Hermann, M; Reubsaet, JL1
Bahrami, G; Kiani, A; Mirzaeei, S; Mohammadi, B1
Baghestanian, M; Ghannadan, M; Hauswirth, AW; Krauth, MT; Majlesi, Y; Müller, MR; Samorapoompichit, P; Schernthaner, GH; Sonneck, K; Sperr, WR; Valent, P; Worda, C1
Anjaneyulu, Y; Boosi, R; Kandikere, VN; Maurya, S; Mudigonda, K; Nirogi, RV; Shukla, M1
Arishima, H; Katafuchi, R; Matsunaga, A; Rye, KA; Saku, K; Zhang, B1
Barrett, B; Borek-Dohalský, V; Huclová, J; Jelínek, I; Nemec, B; Ulc, I1
Ansari Dogaheh, M; Ghorbani Bidkorbeh, F; Hashem, M; Mohammadi, A; Rezanour, N; Walker, RB1
Aukrust, P; Boullier, A; Breland, U; Damås, JK; Fevang, B; Frøland, SS; Gullestad, L; Halvorsen, B; Hansson, GK; Kjekshus, J; Ovchinnikova, O; Quehenberger, O; Robertson, AK; Sandberg, WJ; Smith, C; Taskén, K; Waehre, T; Yndestad, A; Øie, E1
Bohrer, A; Dietzen, DJ; Page, KL; Tetzloff, TA; Turk, J1
Chaudhari, BG; Patel, NM; Shah, PB1
Dogan-Topal, B; Ozkan, SA; Uslu, B1
Manavalan, R; Muralidharan, C; Sivakumar, T; Valliappan, K1
Aprigliano, I; Dudas, J; Ramadori, G; Saile, B1
Mawhinney, DB; Rosario-Ortiz, FL; Snyder, SA; Vanderford, BJ1
Bustos, C; Díaz, C; Egido, J; Hernández, G; Hernández-Presa, MA; Ortego, M; Tuñón, J1
Puri, S; Saucedo, J; Singh, BM; Talley, JD1
Huang, J; Kiener, PA; Knapp, AC; Starling, G1
Hartz, SC; Huse, DM; Kraemer, DF; Miller, JD; Russell, MW1
Dimitroulakos, J; Minden, MD; Penn, LZ; Tan, MM; Wong, WW; Xia, Z1
Alt, E; Banyai, M; Banyai, S; Derfler, K; Falger, J; Jansen, M; Koppensteiner, R1
Gussenhoven, EJ; Hagenaars, T; Poldermans, D; van der Lugt, A; van Urk, H1
Kluft, C1
Engler, H; Korte, W; Noseda, G; Riesen, WF; Risch, M1

Reviews

1 review(s) available for atorvastatin and Sensitivity and Specificity

ArticleYear
Are Canadian guidelines for cholesterol lowering in high-risk patients optimal?
    The Canadian journal of cardiology, 2005, Volume: 21, Issue:1

    Topics: Atorvastatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Maximum Tolerated Dose; Practice Guidelines as Topic; Pravastatin; Prognosis; Pyrroles; Quebec; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome

2005

Trials

8 trial(s) available for atorvastatin and Sensitivity and Specificity

ArticleYear
Effects of Atorvastatin (80 mg) Therapy on Quantity of Epicardial Adipose Tissue in Patients Undergoing Pulmonary Vein Isolation for Atrial Fibrillation.
    The American journal of cardiology, 2015, Nov-01, Volume: 116, Issue:9

    Topics: Adipose Tissue; Anticholesteremic Agents; Atorvastatin; Atrial Fibrillation; Biomarkers; Body Mass Index; C-Reactive Protein; Cholesterol, LDL; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pericardium; Predictive Value of Tests; Prospective Studies; Pulmonary Veins; Sensitivity and Specificity; Tomography, X-Ray Computed; Treatment Outcome

2015
Effect of atorvastatin, vitamin E and C on nonalcoholic fatty liver disease: is the combination required?
    The American journal of gastroenterology, 2011, Volume: 106, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Atorvastatin; Confidence Intervals; Drug Therapy, Combination; Fatty Liver; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Non-alcoholic Fatty Liver Disease; Odds Ratio; Pyrroles; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome; Vitamin A

2011
Prognostic utility of neopterin and risk of heart failure hospitalization after an acute coronary syndrome.
    European heart journal, 2011, Volume: 32, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Atorvastatin; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Heart Failure; Heptanoic Acids; Hospitalization; Humans; Male; Middle Aged; Neopterin; Pravastatin; Proportional Hazards Models; Pyrroles; Sensitivity and Specificity; Treatment Outcome

2011
Atorvastatin metabolite measurements as a diagnostic tool for statin-induced myopathy.
    Molecular diagnosis & therapy, 2011, Aug-01, Volume: 15, Issue:4

    Topics: Adult; Aged; Atorvastatin; Biomarkers; Creatine Kinase; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Muscular Diseases; Pyrroles; Rhabdomyolysis; Sensitivity and Specificity

2011
Simultaneous determination of amlodipine and atorvastatin with its metabolites; ortho and para hydroxy atorvastatin; in human plasma by LC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Feb-15, Volume: 917-918

    Topics: Administration, Oral; Amlodipine; Atorvastatin; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Combinations; Drug Stability; Heptanoic Acids; Humans; Isomerism; Linear Models; Pravastatin; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Therapeutic Equivalency

2013
Atorvastatin lowers lipoprotein(a) but not apolipoprotein(a) fragment levels in hypercholesterolemic subjects at high cardiovascular risk.
    Atherosclerosis, 2002, Volume: 164, Issue:2

    Topics: Adult; Aged; Apolipoproteins A; Atorvastatin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoprotein(a); Logistic Models; Male; Middle Aged; Probability; Pyrroles; Reference Values; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Simvastatin; Statistics, Nonparametric; Treatment Outcome

2002
Rationale and design for the SARIS trial; effect of statin on atherosclerosis and vascular remodeling assessed with intravascular sonography. Effect of Statin on Atherosclerosis and vascular Remodeling assessed with Intravascular Sonography.
    Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:4

    Topics: Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Cholesterol; Coronary Circulation; Echocardiography, Stress; Female; Heptanoic Acids; Humans; Hyperplasia; Male; Multicenter Studies as Topic; Prospective Studies; Pyrroles; Sensitivity and Specificity; Tunica Intima

2001
Short-term effects of atorvastatin on C-reactive protein.
    European heart journal, 2002, Volume: 23, Issue:10

    Topics: Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Female; Follow-Up Studies; Heptanoic Acids; Humans; Male; Pyrroles; Sensitivity and Specificity; Switzerland; Time Factors; Triglycerides

2002

Other Studies

50 other study(ies) available for atorvastatin and Sensitivity and Specificity

ArticleYear
Simultaneous analysis of the total plasma concentration of atorvastatin and its five metabolites and the unbound plasma concentration of atorvastatin: Application in a clinical pharmacokinetic study of single oral dose.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Sep-15, Volume: 1126-1127

    Topics: Administration, Oral; Atorvastatin; Chromatography, High Pressure Liquid; Humans; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2019
Spectrophotometric method for simultaneous determination of valsartan and substances from the group of statins in binary mixtures.
    Acta pharmaceutica (Zagreb, Croatia), 2017, Dec-20, Volume: 67, Issue:4

    Topics: Atorvastatin; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Pravastatin; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry; Valsartan

2017
Quantification of amlodipine and atorvastatin in human plasma by UPLC-MS/MS method and its application to a bioequivalence study.
    Biomedical chromatography : BMC, 2018, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Amlodipine; Atorvastatin; Chromatography, High Pressure Liquid; Humans; Linear Models; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult

2018
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, 09-01, Volume: 1125

    Topics: Amlodipine; Anti-HIV Agents; Atorvastatin; Chromatography, High Pressure Liquid; Drug Interactions; HIV Infections; Humans; Linear Models; Metoprolol; Pravastatin; Reproducibility of Results; Rosuvastatin Calcium; Sensitivity and Specificity; Tandem Mass Spectrometry

2019
Simultaneous estimation of amlodipine and atorvastatin by micelle-augmented first derivative synchronous spectrofluorimetry and multivariate analysis.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Jan-05, Volume: 224

    Topics: Algorithms; Amlodipine; Atorvastatin; Linear Models; Micelles; Multivariate Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

2020
Exploratory analysis on the use of statins with or without n-3 PUFA and major events in patients discharged for acute myocardial infarction: an observational retrospective study.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Aged; Atorvastatin; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Heptanoic Acids; Humans; Kaplan-Meier Estimate; Male; Matched-Pair Analysis; Middle Aged; Myocardial Infarction; Pyrroles; Retrospective Studies; Sensitivity and Specificity; Simvastatin; Treatment Outcome

2013
Differential sensitivity of the species of Candida parapsilosis sensu lato complex against statins.
    Mycopathologia, 2013, Volume: 176, Issue:3-4

    Topics: Anticholesteremic Agents; Antifungal Agents; Atorvastatin; Candida; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Indoles; Microbial Sensitivity Tests; Microbiological Techniques; Pyrroles; Sensitivity and Specificity

2013
MicroRNA-208a Increases Myocardial Endoglin Expression and Myocardial Fibrosis in Acute Myocardial Infarction.
    The Canadian journal of cardiology, 2015, Volume: 31, Issue:5

    Topics: Animals; Atorvastatin; Blotting, Western; Cells, Cultured; Disease Models, Animal; Endoglin; Fibrosis; Gene Expression Regulation; Hemodynamics; Heptanoic Acids; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; MicroRNAs; Muscle Cells; Myocardial Infarction; Polymerase Chain Reaction; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tetrazoles; Valine; Valsartan; Ventricular Remodeling

2015
A Systematic Strategy for Screening and Application of Specific Biomarkers in Hepatotoxicity Using Metabolomics Combined With ROC Curves and SVMs.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 150, Issue:2

    Topics: Acetaminophen; Animals; Atorvastatin; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Liver; Male; Metabolomics; Rats, Wistar; ROC Curve; Sensitivity and Specificity; Support Vector Machine

2016
Pharmaceutical Applications of Relaxation Filter-Selective Signal Excitation Methods for ¹⁹F Solid-State Nuclear Magnetic Resonance: Case Study With Atorvastatin in Dosage Formulation.
    Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:3

    Topics: Acyl Coenzyme A; Atorvastatin; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Fluorine; Fluorine-19 Magnetic Resonance Imaging; Sensitivity and Specificity; Tablets

2016
Stability indicating UPLC method for simultaneous determination of atorvastatin, fenofibrate and their degradation products in tablets.
    Journal of pharmaceutical and biomedical analysis, 2008, Sep-10, Volume: 48, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Buffers; Chromatography, High Pressure Liquid; Drug Contamination; Drug Stability; Fenofibrate; Heptanoic Acids; Hydrogen-Ion Concentration; Molecular Structure; Pyrroles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tablets; Time Factors

2008
Evaluation cardioprotective effects of atorvastatin in rats by real time myocardial contrast echocardiography.
    Echocardiography (Mount Kisco, N.Y.), 2008, Volume: 25, Issue:9

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cardiotonic Agents; Computer Systems; Contrast Media; Echocardiography; Heptanoic Acids; Image Enhancement; Male; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Ventricular Dysfunction, Left

2008
Atorvastatin inhibits renal crystal retention in a rat stone forming model.
    The Journal of urology, 2008, Volume: 180, Issue:5

    Topics: Animals; Apoptosis; Atorvastatin; Biopsy, Needle; Disease Models, Animal; Heptanoic Acids; Immunohistochemistry; Kidney Calculi; Kidney Tubules; Male; Oxalates; Oxidative Stress; Probability; Pyrroles; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Statistics, Nonparametric; Superoxide Dismutase; Urinalysis

2008
Atorvastatin prevents endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats: role of cyclooxygenase 2-derived contracting prostanoids.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:6

    Topics: Analysis of Variance; Animals; Atorvastatin; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelium, Vascular; Heptanoic Acids; Male; Malondialdehyde; Mesenteric Arteries; Probability; Prostaglandins; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sensitivity and Specificity; Vasodilation

2009
Ultra high performance liquid chromatography tandem mass spectrometric detection in clinical analysis of simvastatin and atorvastatin.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Jul-15, Volume: 877, Issue:22

    Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Chromatography, High Pressure Liquid; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Sensitivity and Specificity; Simvastatin; Tandem Mass Spectrometry

2009
Three-dimensional carotid ultrasound segmentation variability dependence on signal difference and boundary orientation.
    Ultrasound in medicine & biology, 2010, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Biometry; Carotid Arteries; Carotid Stenosis; Female; Heptanoic Acids; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Pattern Recognition, Automated; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Surface Properties; Ultrasonography

2010
Identification and assessment of plasma lysozyme as a putative biomarker of atherosclerosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:5

    Topics: Aged; Angina Pectoris; Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Coronary Angiography; Coronary Artery Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoassay; Male; Middle Aged; Muramidase; Predictive Value of Tests; Pyrroles; Sensitivity and Specificity; Severity of Illness Index; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome; Up-Regulation

2010
Simultaneous determination of atorvastatin, amlodipine, ramipril and benazepril in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:4

    Topics: Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Benzazepines; Chromatography, Liquid; Drug Stability; Heptanoic Acids; Humans; Least-Squares Analysis; Male; Nevirapine; Pyrroles; Ramipril; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Simultaneous determination of rosuvastatin and atorvastatin in human serum using RP-HPLC/UV detection: method development, validation and optimization of various experimental parameters.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Mar-15, Volume: 879, Issue:9-10

    Topics: Atorvastatin; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Fluorobenzenes; Heptanoic Acids; Humans; Hydrogen-Ion Concentration; Linear Models; Methanol; Pyrimidines; Pyrroles; Reproducibility of Results; Rosuvastatin Calcium; Sensitivity and Specificity; Sulfonamides; Water

2011
Three different spectrophotometric methods manipulating ratio spectra for determination of binary mixture of Amlodipine and Atorvastatin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2011, Volume: 83, Issue:1

    Topics: Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Heptanoic Acids; Pharmaceutical Preparations; Pyrroles; Sensitivity and Specificity; Spectrophotometry; Tablets

2011
Simultaneous determination of atorvastatin and niacin in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:11

    Topics: Atorvastatin; Chromatography, High Pressure Liquid; Drug Stability; Heptanoic Acids; Humans; Linear Models; Liquid-Liquid Extraction; Male; Nevirapine; Niacin; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2012
Development and validation of stability-indicating assay method by UPLC for a fixed dose combination of atorvastatin and ezetimibe.
    Journal of chromatographic science, 2013, Volume: 51, Issue:3

    Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Ezetimibe; Heptanoic Acids; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Tablets

2013
Coronary artery spasm associated with a moderately severe atherosclerotic stenosis in the proximal LAD.
    The Journal of invasive cardiology, 2002, Volume: 14, Issue:12

    Topics: Adult; Aspirin; Atorvastatin; Cardiac Catheterization; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heptanoic Acids; Humans; Isosorbide; Pyrroles; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Ultrasonography, Interventional

2002
Determination of pharmaceuticals in aqueous samples using positive and negative voltage switching microbore liquid chromatography/electrospray ionization tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2003, Volume: 38, Issue:1

    Topics: Atorvastatin; Chromatography, Liquid; Heptanoic Acids; Molecular Structure; Novobiocin; Pharmaceutical Preparations; Pyrroles; Reference Standards; Roxithromycin; Sensitivity and Specificity; Solutions; Spectrometry, Mass, Electrospray Ionization; Water; Water Pollutants, Chemical

2003
Plasma fibronectin level and its relationships with lipids, lipoproteins and C-reactive protein in patients with dyslipidaemia during lipid-lowering therapy.
    Acta cardiologica, 2002, Volume: 57, Issue:6

    Topics: Adult; Aged; Apolipoproteins A; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Female; Fibronectins; Follow-Up Studies; Heptanoic Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Probability; Prospective Studies; Pyrroles; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome

2002
The importance of indirect costs in primary cardiovascular disease prevention: can we save lives and money with statins?
    Archives of internal medicine, 2003, Feb-10, Volume: 163, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Atorvastatin; Canada; Cardiovascular Diseases; Cost of Illness; Cost-Benefit Analysis; Direct Service Costs; Efficiency; Female; Health Care Costs; Health Expenditures; Heptanoic Acids; Humans; Hypolipidemic Agents; Life Expectancy; Male; Middle Aged; Primary Prevention; Pyrroles; Sensitivity and Specificity

2003
Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes.
    Diabetes care, 2003, Volume: 26, Issue:6

    Topics: Atorvastatin; Cholesterol, LDL; Coronary Disease; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Sensitivity and Specificity; Simvastatin; United States

2003
[Cost-effectiveness of atorvastatin for the prevention of coronary disease. An analysis of the ASCOT study].
    Deutsche medizinische Wochenschrift (1946), 2004, Jun-18, Volume: 129, Issue:25-26

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Coronary Artery Disease; Cost-Benefit Analysis; Female; Germany; Health Care Costs; Heptanoic Acids; Humans; Hypertension; Male; Middle Aged; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome

2004
Effect of atorvastatin on the expression of CD40 ligand and P-selectin on platelets in patients with hypercholesterolemia.
    The American journal of cardiology, 2004, Aug-01, Volume: 94, Issue:3

    Topics: Adult; Atorvastatin; Biomarkers; Case-Control Studies; CD40 Ligand; Cohort Studies; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; P-Selectin; Probability; Prognosis; Pyrroles; Reference Values; Sensitivity and Specificity; Severity of Illness Index

2004
Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LC-tandem MS.
    Analytical and bioanalytical chemistry, 2005, Volume: 382, Issue:5

    Topics: Atorvastatin; Biotransformation; Chromatography, High Pressure Liquid; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Molecular Structure; Pyrroles; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry

2005
Determination of atorvastatin in human serum by reversed-phase high-performance liquid chromatography with UV detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Nov-05, Volume: 826, Issue:1-2

    Topics: Atorvastatin; Chromatography, High Pressure Liquid; Heptanoic Acids; Humans; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2005
Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells.
    Allergy, 2006, Volume: 61, Issue:3

    Topics: Apoptosis; Atorvastatin; Cell Differentiation; Cell Division; Cell Proliferation; Cells, Cultured; Cytokines; Heptanoic Acids; Histamine Release; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin E; Lovastatin; Mast Cells; Probability; Pyridines; Pyrroles; Sensitivity and Specificity

2006
Simultaneous quantification of atorvastatin and active metabolites in human plasma by liquid chromatography-tandem mass spectrometry using rosuvastatin as internal standard.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:9

    Topics: Atorvastatin; Biological Availability; Calibration; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mass Spectrometry; Pyrroles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Therapeutic Equivalency

2006
Effects of atorvastatin and apoA-I/phosphatidylcholine discs on triglyceride-rich lipoprotein subfractions as characterized by capillary isotachophoresis.
    Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 373, Issue:1-2

    Topics: Adult; Apolipoprotein A-I; Apolipoprotein E2; Atorvastatin; Electrophoresis, Capillary; Heptanoic Acids; Humans; Hyperlipoproteinemia Type III; Lipoproteins; Macromolecular Substances; Male; Phenotype; Phosphatidylcholines; Pyrroles; Sensitivity and Specificity; Time Factors; Triglycerides

2006
Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study.
    Analytical and bioanalytical chemistry, 2006, Volume: 386, Issue:2

    Topics: Anticholesteremic Agents; Atorvastatin; Chromatography, High Pressure Liquid; Heptanoic Acids; Humans; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2006
A stability-indicating high performance liquid chromatographic (HPLC) assay for the simultaneous determination of atorvastatin and amlodipine in commercial tablets.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Feb-01, Volume: 846, Issue:1-2

    Topics: Amlodipine; Atorvastatin; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets

2007
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Animals; Apolipoproteins E; Atherosclerosis; Atorvastatin; Biopsy, Needle; Cells, Cultured; Chemokine CCL19; Chemokine CCL21; Chemokines, CC; Coronary Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Gene Expression Regulation; Heptanoic Acids; Humans; Immunohistochemistry; In Vitro Techniques; Leukocytes, Mononuclear; Mice; Mice, Transgenic; Prognosis; Pyrroles; Receptors, CCR7; Receptors, Chemokine; Reference Values; Risk Factors; RNA, Messenger; Sensitivity and Specificity; Simvastatin; Treatment Outcome

2007
Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase blunts factor VIIa/tissue factor and prothrombinase activities via effects on membrane phosphatidylserine.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:3

    Topics: Animals; Atorvastatin; Blotting, Western; Cattle; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Factor VIIa; Fibroblasts; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Phosphatidylserines; Pyrroles; Sensitivity and Specificity; Thromboplastin

2007
Stability indicating RP-HPLC method for simultaneous determination of atorvastatin and amlodipine from their combination drug products.
    Chemical & pharmaceutical bulletin, 2007, Volume: 55, Issue:2

    Topics: Amlodipine; Anticholesteremic Agents; Atorvastatin; Calcium Channel Blockers; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Heptanoic Acids; Hydrolysis; Oxidative Stress; Photolysis; Pyrroles; Quality Control; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Temperature; Time Factors

2007
Investigation of electrochemical behavior of lipid lowering agent atorvastatin calcium in aqueous media and its determination from pharmaceutical dosage forms and biological fluids using boron-doped diamond and glassy carbon electrodes.
    Combinatorial chemistry & high throughput screening, 2007, Volume: 10, Issue:7

    Topics: Atorvastatin; Boron; Carbon; Diamond; Electrochemistry; Electrodes; Heptanoic Acids; Humans; Hydrogen-Ion Concentration; Hypolipidemic Agents; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Pyrroles; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Solutions; Tablets; Water

2007
An improved HPLC method with the aid of a chemometric protocol: simultaneous analysis of amlodipine and atorvastatin in pharmaceutical formulations.
    Journal of separation science, 2007, Volume: 30, Issue:18

    Topics: Amlodipine; Atorvastatin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Heptanoic Acids; Models, Chemical; Molecular Structure; Pyrroles; Reproducibility of Results; Sensitivity and Specificity

2007
Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:4

    Topics: Analysis of Variance; Animals; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Blotting, Western; Caspase 9; Cells, Cultured; Disease Models, Animal; Fas Ligand Protein; Female; Flow Cytometry; Hepatocytes; Heptanoic Acids; JNK Mitogen-Activated Protein Kinases; Male; Microscopy, Confocal; NF-kappa B; Probability; Pyrroles; Rats; Rats, Wistar; Sensitivity and Specificity

2008
Real-time detection and identification of aqueous chlorine transformation products using QTOF MS.
    Analytical chemistry, 2008, Jun-01, Volume: 80, Issue:11

    Topics: Atorvastatin; Chlorine; Halogenation; Heptanoic Acids; Mass Spectrometry; Methanol; Pharmaceutical Preparations; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Time Factors; Triclosan; Water; Water Pollutants, Chemical

2008
Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells.
    Atherosclerosis, 1999, Volume: 147, Issue:2

    Topics: Animals; Atorvastatin; Base Sequence; Blotting, Western; Cells, Cultured; Chemokines; Coronary Artery Disease; Coronary Vessels; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Molecular Sequence Data; Monocytes; Muscle, Smooth, Vascular; NF-kappa B; Polymerase Chain Reaction; Pyrroles; Rats; Reproducibility of Results; Sensitivity and Specificity

1999
Atorvastatin versus revascularization treatment (AVERT): fact or fancy?
    American heart journal, 2000, Volume: 140, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Coronary Disease; Heptanoic Acids; Humans; Myocardial Revascularization; Patient Selection; Pyrroles; Sensitivity and Specificity; Treatment Outcome

2000
Inhibitors of HMG-CoA reductase sensitize human smooth muscle cells to Fas-ligand and cytokine-induced cell death.
    Atherosclerosis, 2000, Volume: 152, Issue:1

    Topics: Apoptosis; Atorvastatin; Cell Survival; Cells, Cultured; Coronary Vessels; Cytokines; Dose-Response Relationship, Drug; Endothelium, Vascular; Fas Ligand Protein; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Membrane Glycoproteins; Muscle, Smooth, Vascular; Pravastatin; Pyrroles; Reference Values; Sensitivity and Specificity; Simvastatin

2000
Cost effectiveness of HMG-CoA reductase inhibition in Canada.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2001,Spring, Volume: 8, Issue:1

    Topics: Aged; Atorvastatin; Canada; Coronary Disease; Cost-Benefit Analysis; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Sensitivity and Specificity

2001
Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:7

    Topics: Acute Disease; Apoptosis; Atorvastatin; Cell Division; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Leukemia, Myeloid; Lovastatin; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyridines; Pyrroles; Sensitivity and Specificity; Tumor Cells, Cultured

2001
Atorvastatin improves blood rheology in patients with familial hypercholesterolemia (FH) on long-term LDL apheresis treatment.
    Atherosclerosis, 2001, Volume: 159, Issue:2

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Blood Viscosity; Combined Modality Therapy; Erythrocyte Aggregation; Female; Fibrinogen; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Plasmapheresis; Probability; Prospective Studies; Pyrroles; Rheology; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome

2001
Is C-reactive protein an additional, surrogate end-point for statin treatment?
    European heart journal, 2002, Volume: 23, Issue:10

    Topics: Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Heptanoic Acids; Humans; Pyrroles; Sensitivity and Specificity; Triglycerides

2002