Page last updated: 2024-08-07 15:30:31
Dihydrofolate reductase
A dihydrofolate reductase that is encoded in the genome of chicken. [PRO:DAN]
Synonyms
EC 1.5.1.3
Research
Bioassay Publications (10)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (14)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| trimethoprim | Gallus gallus (chicken) | IC50 | 493.3333 | 3 | 3 |
| trimethoprim | Gallus gallus (chicken) | Ki | 104.7130 | 2 | 2 |
| cycloguanil | Gallus gallus (chicken) | Ki | 0.1122 | 1 | 1 |
| congo red | Gallus gallus (chicken) | IC50 | 0.4000 | 1 | 1 |
| 4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine | Gallus gallus (chicken) | Ki | 0.2042 | 1 | 1 |
| diaveridine | Gallus gallus (chicken) | IC50 | 300.0000 | 1 | 1 |
| diaveridine | Gallus gallus (chicken) | Ki | 34.6737 | 1 | 1 |
| tetroxoprim | Gallus gallus (chicken) | Ki | 229.0870 | 2 | 2 |
| metioprim | Gallus gallus (chicken) | Ki | 51.2861 | 1 | 1 |
| aditoprim | Gallus gallus (chicken) | Ki | 70.7946 | 1 | 1 |
| brodimoprim | Gallus gallus (chicken) | Ki | 28.8403 | 1 | 1 |
| epiroprim | Gallus gallus (chicken) | Ki | 46.7735 | 1 | 1 |
| iodophthalein | Gallus gallus (chicken) | IC50 | 20.0000 | 1 | 1 |
| 2,4-diamino-5-benzylpyrimidine | Gallus gallus (chicken) | Ki | 19.4985 | 3 | 3 |
| 2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine | Gallus gallus (chicken) | Ki | 0.3311 | 1 | 1 |
| methotrexate | Gallus gallus (chicken) | IC50 | 0.0545 | 2 | 2 |