Page last updated: 2024-11-07

n-acetylasparagine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-acetylasparagine (NAA) is a naturally occurring amino acid derivative found in various biological systems. It is synthesized through the acetylation of asparagine, catalyzed by the enzyme asparagine N-acetylase. NAA has been implicated in a range of physiological processes, including neurotransmission, cell signaling, and immune responses. Research suggests that NAA may play a role in the development and function of the nervous system. It is also studied as a potential biomarker for certain neurological disorders, such as multiple sclerosis. The importance of NAA stems from its potential involvement in various biological pathways and its potential utility as a diagnostic and therapeutic tool.'

N-acetylasparagine: RN given refers to (L)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID99715
CHEMBL ID4778641
CHEBI ID139582
SCHEMBL ID468797
MeSH IDM0088089

Synonyms (41)

Synonym
4033-40-3
n-acetylasparagine
nalpha-acetyl-l-asparagine, 98%
n2-acetyl-l-asparagine
nalpha-acetyl-l-asparagine
n-alpha-acetyl-l-asparagine
CHEBI:139582
n-acetyl-l-asparagine
(2s)-2-acetamido-4-amino-4-oxobutanoic acid
na-acetyl-l-asparagine
unii-d0p42n84z6
d0p42n84z6 ,
nsc 186895
einecs 223-716-7
(s)-2-acetamido-4-amino-4-oxobutanoic acid
n|a-acetyl-l-asparagine
S2989
acetyl-l-asparagine
AM81557
.alpha.-n-acetyl-l-asparagine
l-asparagine, n2-acetyl-
asparagine, n2-acetyl-, l-
SCHEMBL468797
AKOS016843261
W-106362
FD21163
mfcd00066023
(2s)-3-carbamoyl-2-acetamidopropanoic acid
acasn
acetylasparagine
HY-W016798
AS-48981
a-n-acetyl-l-asparagine
Q27275946
CS-W017514
n alpha -acetyl-l-asparagine
EN300-871074
(s)-2-acetamido-4-amino-4-oxobutanoicacid
CHEMBL4778641
DTXSID401035921
EX-A7843F
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
asparagine derivativeAn amino acid derivative resulting from reaction of asparagine at the amino group, the carboxy group, or the carboxamide, or from the replacement of any hydrogen of asparagine by a heteroatom. The definition normally excludes peptides containing asparagine residues.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.02 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.02)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]