Proteins > calpain II, partial
Page last updated: 2024-08-07 12:28:53

calpain II, partial

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (60)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
benzbromaroneSus scrofa (pig)IC506.426010
bay h 4502Sus scrofa (pig)IC5014.706010
bithionolSus scrofa (pig)IC504.751210
hexachloropheneSus scrofa (pig)IC503.733610
aloxistatinSus scrofa (pig)IC501.774210
2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)diimino)bis-benzoic acidSus scrofa (pig)IC502.867510
2-acetamido-4-chloromethylthiazoleSus scrofa (pig)IC5050.000010
Glyceryl lactopalmitateSus scrofa (pig)IC5050.000010
4-cyclohexyl-3-[(3-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thioneSus scrofa (pig)IC5014.993210
2-(4-hydroxyanilino)-1,4-naphthoquinoneSus scrofa (pig)IC505.095810
1-(4-ethylphenyl)-N-(3-pyridinylmethyl)methanamineSus scrofa (pig)IC500.454110
4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thioneSus scrofa (pig)IC5022.100610
3-anilino-1-(3-nitrophenyl)-1-propanoneSus scrofa (pig)IC5014.127010
2-(2-methylphenoxy)-N-[2-(methylthio)phenyl]acetamideSus scrofa (pig)IC508.860310
N-(4-methoxyphenyl)-2-(methylthio)benzamideSus scrofa (pig)IC508.101410
1-(3,4-dichlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaSus scrofa (pig)IC503.635610
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(3-pyridinyl)-4-quinolinecarboxamideSus scrofa (pig)IC5050.000010
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thioneSus scrofa (pig)IC5014.334410
5-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-1,2-dihydro-1,2,4-triazole-3-thioneSus scrofa (pig)IC5010.110110
N-[1-methyl-3-(trifluoromethyl)-5-thieno[2,3-c]pyrazolyl]carbamic acid (4-fluorophenyl)methyl esterSus scrofa (pig)IC506.721210
4-butyl-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thioneSus scrofa (pig)IC5050.000010
4-phenyl-N-[sulfanylidene-(2,4,6-trimethylanilino)methyl]benzamideSus scrofa (pig)IC5012.390910
2-[[1-oxo-2-(2-pyrimidinylthio)ethyl]amino]-6-(phenylmethyl)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylic acid ethyl esterSus scrofa (pig)IC505.712410
2-[[6-(butylsulfamoyl)-1H-benzimidazol-2-yl]thio]-N-(2-chlorophenyl)acetamideSus scrofa (pig)IC5018.529610
N-[(tert-butylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamideSus scrofa (pig)IC5019.120310
4-chloro-3-(1-piperidinylsulfonyl)benzoic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] esterSus scrofa (pig)IC5029.197010
N-[2-(cyclohexylthio)ethyl]-4-methyl-3-[(4-methylphenyl)sulfamoyl]benzamideSus scrofa (pig)IC5050.000010
4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] esterSus scrofa (pig)IC507.155610
N-(4-acetamidophenyl)-2-[5-(1-piperidinylsulfonyl)-2-thiophenyl]acetamideSus scrofa (pig)IC502.642910
5-(3-fluorophenoxy)-8-nitroisoquinolineSus scrofa (pig)IC503.502010
5-methyl-4-(4-methylphenyl)-2-[[2-[(1-methyl-5-tetrazolyl)thio]-1-oxoethyl]amino]-3-thiophenecarboxylic acid ethyl esterSus scrofa (pig)IC505.101310
2-[4-(2-methylpropyl)phenyl]propanoic acid [2-(1H-indol-3-yl)-2-oxoethyl] esterSus scrofa (pig)IC506.654610
1-hexadecyl-3-methylimidazolium bromideSus scrofa (pig)IC5011.387510
N-[2-(4-methoxyphenoxy)ethyl]-5-(4-morpholinyl)-2-nitroanilineSus scrofa (pig)IC5013.838710
N-(4-methylphenyl)-5-nitro-4-spiro[benzimidazole-2,1'-cyclohexane]amineSus scrofa (pig)IC501.581310
2,4-dichloro-6-[1-(4-morpholinyl)-3-phenylprop-2-ynyl]phenolSus scrofa (pig)IC5012.820810
N-(5-bromo-2-pyridinyl)-2,2-dimethyl-3-(2-methylprop-1-enyl)-1-cyclopropanecarboxamideSus scrofa (pig)IC506.335410
[4-(2-methoxyphenyl)-1-piperazinyl]-[4-[(phenylthio)methyl]phenyl]methanoneSus scrofa (pig)IC508.992310
LSM-25805Sus scrofa (pig)IC508.523610
4-(1,3-benzodioxol-5-yl)-6-[[2-(4-chlorophenyl)ethylamino]methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl esterSus scrofa (pig)IC5050.000010
3-ethyl-4-oxo-1-phthalazinecarboxylic acid [2-(1H-indol-3-yl)-2-oxoethyl] esterSus scrofa (pig)IC503.990810
2-(2,3,3-trichloro-1-nitroprop-2-enylidene)-1,3-dihydrobenzimidazoleSus scrofa (pig)IC5027.792710
2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamideSus scrofa (pig)IC5024.890310
2-[7-oxo-7-(3-phenyl-1-pyrrolidinyl)heptyl]isoindole-1,3-dioneSus scrofa (pig)IC507.708710
1-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-4-piperidinecarboxylic acid ethyl esterSus scrofa (pig)IC5011.453810
3,4-dihydro-2H-quinolin-1-yl-[5-(4-methoxyphenyl)-3-isoxazolyl]methanoneSus scrofa (pig)IC5013.399510
4-butyl-3-(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-1H-1,2,4-triazole-5-thioneSus scrofa (pig)IC5018.222810
N4-(2-furanylmethyl)-N2-(3-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamineSus scrofa (pig)IC507.894610
1-(4-chlorophenyl)-3-[2-(2-furanylmethyl)cyclohexyl]ureaSus scrofa (pig)IC502.687710
2-phenylbutanoic acid [2-oxo-2-(2-phenylanilino)ethyl] esterSus scrofa (pig)IC509.963710
1-[2-(5-chloro-2-methyl-1H-indol-3-yl)ethyl]-3-ethyl-1-(2-furanylmethyl)thioureaSus scrofa (pig)IC509.050510
N-[4-(phenoxymethyl)-2-thiazolyl]-1-adamantanecarboxamideSus scrofa (pig)IC502.029310
N-(2,5-dimethoxyphenyl)-4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1H-quinazoline-7-carboxamideSus scrofa (pig)IC5012.980410
N-(3,4-dimethylphenyl)-2-[[5-[3-(4-methoxyphenyl)propyl]-1,3,4-oxadiazol-2-yl]thio]acetamideSus scrofa (pig)IC500.400010
N-(1,3-benzodioxol-5-yl)-6-chloro-2-(2-pyridinyl)-3-imidazo[1,2-a]pyridinamineSus scrofa (pig)IC500.608010
5-nitro-N-[(4-propan-2-ylphenyl)methyl]-2-pyridinamineSus scrofa (pig)IC506.029110
2-(4,5,6,7-tetrahydroindazol-2-yl)-N-(2,4,6-trimethylphenyl)acetamideSus scrofa (pig)IC5020.510910
dihydroxanthohumolSus scrofa (pig)IC505.000410
(2S)-4-methyl-2-[[oxo-[5-[oxo-[(phenylmethyl)amino]methyl]-1H-imidazol-4-yl]methyl]amino]pentanoic acid tert-butyl esterSus scrofa (pig)IC5010.814110
(2S)-4-methyl-2-[[[5-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]pentanoic acid tert-butyl esterSus scrofa (pig)IC5026.618910