sumatriptan has been researched along with Sensitivity and Specificity in 15 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This method was successfully applied to a pharmacokinetic study conducted with 10 healthy volunteers." | 1.39 | Rapid determination of sumatriptan in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetic study. ( Bae, MH; Lee, HW; Lee, J; Lim, MS; Park, J; Park, SM; Seo, JJ; Seong, SJ; Yoon, YR, 2013) |
| "Sumatriptan was recovered from plasma (81." | 1.32 | Validation and application of a high-performance liquid chromatography/tandem mass spectrometry assay for sumatriptan in human plasma. ( Boulton, DW; Duncan, GF; Vachharajani, NN, 2003) |
| " Pharmacokinetic parameters evaluated after administration of single intravenous and oral doses were very similar and the ANOVA analysis did not show any statistically significant differences for t1/2, Cmax, V or AUC (normalised)." | 1.30 | A method using a liquid chromatographic-electrospray-mass spectrometric assay for the determination of antimigraine compounds: preliminary pharmacokinetics of MDL 74,721, sumatriptan and naratriptan, in rabbit. ( David, M; Duléry, BD; Huebert, ND; Petty, MA; Schoun, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, JJ | 1 |
| Park, J | 1 |
| Bae, MH | 1 |
| Lim, MS | 1 |
| Seong, SJ | 1 |
| Lee, J | 1 |
| Park, SM | 1 |
| Lee, HW | 1 |
| Yoon, YR | 1 |
| Yadav, M | 1 |
| Patel, C | 1 |
| Patel, M | 1 |
| Mishra, T | 1 |
| Baxi, GA | 1 |
| Singhal, P | 2 |
| Shrivastav, PS | 2 |
| Patel, DP | 1 |
| Sharma, P | 1 |
| Sanyal, M | 1 |
| Cózar-Bernal, MJ | 1 |
| Rabasco, AM | 1 |
| González-Rodríguez, ML | 1 |
| Vanmolkot, FH | 1 |
| de Hoon, JN | 1 |
| Barrington, P | 1 |
| Peck, RW | 1 |
| Dallow, NS | 1 |
| Williams, PM | 1 |
| McColm, J | 1 |
| Boulton, DW | 1 |
| Duncan, GF | 1 |
| Vachharajani, NN | 1 |
| Tack, J | 1 |
| Caenepeel, P | 1 |
| Piessevaux, H | 1 |
| Cuomo, R | 1 |
| Janssens, J | 1 |
| Ge, Z | 1 |
| Tessier, E | 1 |
| Neirinck, L | 1 |
| Zhu, Z | 1 |
| MacLean, MR | 1 |
| Clayton, RA | 1 |
| Hillis, SW | 1 |
| McIntyre, PD | 1 |
| Peacock, AJ | 1 |
| Templeton, AG | 1 |
| Altria, KD | 1 |
| Franklin, M | 2 |
| Odontiadis, J | 2 |
| Clement, EM | 1 |
| Duléry, BD | 1 |
| Petty, MA | 1 |
| Schoun, J | 1 |
| David, M | 1 |
| Huebert, ND | 1 |
| Evans, KW | 1 |
| Boan, JA | 1 |
| Evans, JL | 1 |
| Shuaib, A | 1 |
| Vishwanathan, K | 1 |
| Bartlett, MG | 1 |
| Stewart, JT | 1 |
2 trials available for sumatriptan and Sensitivity and Specificity
| Article | Year |
|---|---|
Non-invasive assessment of selective 5-HT(1B/1D)-receptor agonist-induced peripheral vascular effects in humans: comparison of different techniques.
Topics: Adult; Arm; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Metho | 2002 |
Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia.
Topics: Adult; Analysis of Variance; Case-Control Studies; Cisapride; Cross-Over Studies; Double-Blind Metho | 2003 |
13 other studies available for sumatriptan and Sensitivity and Specificity
| Article | Year |
|---|---|
Rapid determination of sumatriptan in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetic study.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Linear Models; Male; Reproducibility o | 2013 |
Development and validation of a sensitive and rapid method to determine naratriptan in human plasma by LC-ESI-MS-MS: application to a bioequivalence study.
Topics: Adult; Area Under Curve; Chromatography, Liquid; Drug Stability; Humans; Piperidines; Reproducibilit | 2011 |
Challenges in the simultaneous quantitation of sumatriptan and naproxen in human plasma: application to a bioequivalence study.
Topics: Adult; Chromatography, High Pressure Liquid; Drug Stability; Humans; India; Linear Models; Male; Nap | 2012 |
Development and validation of a high performance chromatographic method for determining sumatriptan in niosomes.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Lipo | 2013 |
Validation and application of a high-performance liquid chromatography/tandem mass spectrometry assay for sumatriptan in human plasma.
Topics: Administration, Intranasal; Area Under Curve; Chromatography, High Pressure Liquid; Humans; Male; Se | 2003 |
High performance liquid chromatographic method for the determination of sumatriptan with fluorescence detection in human plasma.
Topics: Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sensitivity and Specificit | 2004 |
5-HT1-receptor-mediated vasoconstriction in bovine isolated pulmonary arteries: influences of vascular endothelium and tone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Drug Interactions; Endothelium, Vascular; In | 1994 |
Application of capillary electrophoresis to pharmaceutical analysis.
Topics: Albuterol; Capillary Action; Chromatography, High Pressure Liquid; Electrophoresis; Pharmaceutical P | 1996 |
Determination of sumatriptan succinate in human plasma by high-performance liquid chromatography with coulometric detection and utilization of solid-phase extraction.
Topics: Chromatography, High Pressure Liquid; Humans; Male; Naloxone; Sensitivity and Specificity; Serotonin | 1996 |
Determination of naloxone in human plasma by high-performance liquid chromatography with coulometric detection.
Topics: Analysis of Variance; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Injections, In | 1996 |
A method using a liquid chromatographic-electrospray-mass spectrometric assay for the determination of antimigraine compounds: preliminary pharmacokinetics of MDL 74,721, sumatriptan and naratriptan, in rabbit.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Indoles; Injections, Intravenous; Male; Mass | 1997 |
Economic evaluation of oral sumatriptan compared with oral caffeine/ergotamine for migraine.
Topics: Administration, Oral; Caffeine; Cost-Benefit Analysis; Ergotamine; Migraine Disorders; Sensitivity a | 1997 |
Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry.
Topics: Bufotenin; Chromatography, High Pressure Liquid; Humans; Indoles; Mass Spectrometry; Migraine Disord | 2000 |