porphobilinogen has been researched along with Sensitivity and Specificity in 15 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Accurate determinations of 5-aminolevulinic acid (ALA) and porphobilinogen (PBG) in physiologic fluids are required for the diagnosis and therapeutic monitoring of acute porphyrias." | 3.77 | A LC-MS/MS method for the specific, sensitive, and simultaneous quantification of 5-aminolevulinic acid and porphobilinogen. ( Balwani, M; Bishop, D; Desnick, RJ; Yasuda, M; Yu, C; Zhang, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, XF | 1 |
| Ma, Q | 1 |
| Wang, Z | 1 |
| Xie, Z | 1 |
| Song, Y | 1 |
| Ma, Y | 1 |
| Yang, Z | 1 |
| Zhao, X | 1 |
| Sardh, E | 1 |
| Harper, P | 1 |
| Andersson, DE | 1 |
| Floderus, Y | 1 |
| Zhang, J | 1 |
| Yasuda, M | 1 |
| Desnick, RJ | 1 |
| Balwani, M | 1 |
| Bishop, D | 1 |
| Yu, C | 1 |
| Benton, CM | 2 |
| Couchman, L | 2 |
| Marsden, JT | 2 |
| Rees, DC | 2 |
| Moniz, C | 2 |
| Lim, CK | 3 |
| Kauppinen, R | 2 |
| von und zu Fraunberg, M | 1 |
| Zuijderhoudt, FM | 1 |
| Weykamp, CW | 1 |
| Willems, HL | 1 |
| To-Figueras, J | 1 |
| Badenas, C | 1 |
| Carrera, C | 1 |
| Muñoz, C | 1 |
| Milá, M | 1 |
| Lecha, M | 1 |
| Herrero, C | 1 |
| Schoenfeld, N | 1 |
| Mamet, R | 1 |
| Deacon, AC | 1 |
| Peters, TJ | 1 |
| Lord, GA | 1 |
| Luo, JL | 1 |
| Gorchein, A | 1 |
| Buttery, JE | 2 |
| Carrera, AM | 2 |
| Pannall, PR | 2 |
1 review available for porphobilinogen and Sensitivity and Specificity
| Article | Year |
|---|---|
Molecular diagnostics of acute intermittent porphyria.
Topics: Genetic Testing; Humans; Molecular Diagnostic Techniques; Mutation; Porphobilinogen; Porphyria, Acut | 2004 |
1 trial available for porphobilinogen and Sensitivity and Specificity
| Article | Year |
|---|---|
Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug | 2009 |
13 other studies available for porphobilinogen and Sensitivity and Specificity
| Article | Year |
|---|---|
A Boron Dipyrromethene-Based Fluorescence 'OFF-ON' Probe for Sensitive and Selective Detection of Palladium(II) Ions and Its Application in Live Cell Imaging.
Topics: A549 Cells; Boron Compounds; Fluorescent Dyes; Humans; Palladium; Porphobilinogen; Sensitivity and S | 2020 |
A LC-MS/MS method for the specific, sensitive, and simultaneous quantification of 5-aminolevulinic acid and porphobilinogen.
Topics: Adolescent; Adult; Aminolevulinic Acid; Animals; Child; Child, Preschool; Chromatography, Liquid; Di | 2011 |
Direct and simultaneous determination of 5-aminolaevulinic acid and porphobilinogen in urine by hydrophilic interaction liquid chromatography-electrospray ionisation/tandem mass spectrometry.
Topics: Aminolevulinic Acid; Analysis of Variance; Chromatography, Liquid; Humans; Hydrophobic and Hydrophil | 2012 |
Direct and simultaneous quantitation of 5-aminolaevulinic acid and porphobilinogen in human serum or plasma by hydrophilic interaction liquid chromatography-atmospheric pressure chemical ionization/tandem mass spectrometry.
Topics: Aminolevulinic Acid; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Least | 2013 |
Molecular and biochemical studies of acute intermittent porphyria in 196 patients and their families.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; DNA; Family; Feces; Female; Humans; Hydroxymethylbilan | 2002 |
Measurement of urinary porphyrins and porphyrin precursors in Dutch hospital laboratories: a review of quality control over 5 years.
Topics: Aminolevulinic Acid; Clinical Chemistry Tests; Coproporphyrins; Humans; Laboratories, Hospital; Neth | 2003 |
Genetic and biochemical characterization of 16 acute intermittent porphyria cases with a high prevalence of the R173W mutation.
Topics: Adolescent; Adult; DNA Mutational Analysis; Female; Humans; Hydroxymethylbilane Synthase; Male; Midd | 2006 |
Individualized workup: a new approach to the biochemical diagnosis of acute attacks of neuroporphyria.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent | 2006 |
Identification of acute porphyria: evaluation of a commercial screening test for urinary porphobilinogen.
Topics: Acute Disease; Evaluation Studies as Topic; Humans; Porphobilinogen; Porphyrias; Reagent Kits, Diagn | 1998 |
Capillary zone electrophoresis/mass spectrometry of 5-aminolaevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Electrophoresis, Capillary; Mass Spectrometry; Porphobilinogen; Sensitivity and | 2000 |
Testing for porphobilinogen in urine.
Topics: Humans; Porphobilinogen; Porphyria, Acute Intermittent; Sensitivity and Specificity | 2002 |
Reliability of the porphobilinogen screening assay.
Topics: Clinical Laboratory Techniques; Humans; Porphobilinogen; Porphyrias; Sensitivity and Specificity | 1990 |
Analytical sensitivity and specificity of two screening methods for urinary porphobilinogen.
Topics: Colorimetry; Humans; Porphobilinogen; Sensitivity and Specificity | 1990 |