clonidine has been researched along with Sensitivity and Specificity in 50 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was aimed at comparing the diagnostic accuracy of the growth hormone (GH) response to clonidine, arginine and both combined in order to establish a more reliable test to differentiate parkinsonism type multiple system atrophy (MSA-p) from Parkinson's disease (PD)." | 9.14 | The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease. ( Fu, Y; Song, C; Wan, Q; Zeng, Y; Zhang, K, 2010) |
| "The diagnosis of pheochromocytoma/paraganglioma (PPGL) involves detection of elevated levels of plasma and/or 24-h urine catecholamines and/or their metabolites, including metanephrines." | 7.81 | Urinary clonidine suppression testing for the diagnosis of pheochromocytoma. ( Fountoulakis, S; Gordon, RD; Goupil, R; Stowasser, M, 2015) |
| "The clonidine test has been proposed as diagnostic biochemical test for patients with clinical suspicion of pheochromocytoma." | 7.71 | [Usefulness of the clonidine test for the diagnosis of pheochromocytoma]. ( Fernández-Torres, C; Hidalgo Tenorio, C; Jiménez-Alonso, J; León-Ruiz, L; López de la Torre Casares, M; Mediavilla García, JD; Piédrola Maroto, G; Pinel Julián, P, 2001) |
| "We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor." | 7.68 | Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991) |
| "Apraclonidine (0." | 5.33 | The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis. ( Acaroglu, G; Firat, E; Kansu, T; Kavuncu, S; Koc, F, 2005) |
| "This study was aimed at comparing the diagnostic accuracy of the growth hormone (GH) response to clonidine, arginine and both combined in order to establish a more reliable test to differentiate parkinsonism type multiple system atrophy (MSA-p) from Parkinson's disease (PD)." | 5.14 | The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease. ( Fu, Y; Song, C; Wan, Q; Zeng, Y; Zhang, K, 2010) |
| "Epinephrine or isoproterenol is a reliable marker to detect accidental intravascular injection of a test dose with 100% sensitivity and specificity based on a new heart rate criterion in sevoflurane-anesthetized children." | 5.09 | Oral clonidine premedication does not change efficacy of simulated epidural test dose in sevoflurane-anesthetized children. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M; Uesugi, T, 2000) |
| "The purpose of this paper is to report our experience and to review the published data on the diagnostic significance and risks of the clonidine suppression test in the diagnosis of pheochromocytoma." | 4.80 | Clonidine suppression test revisited. ( Geiger, H; Lenz, T; Ross, A; Schulte, KL; Schumm-Draeger, P, 1998) |
| "The diagnosis of pheochromocytoma/paraganglioma (PPGL) involves detection of elevated levels of plasma and/or 24-h urine catecholamines and/or their metabolites, including metanephrines." | 3.81 | Urinary clonidine suppression testing for the diagnosis of pheochromocytoma. ( Fountoulakis, S; Gordon, RD; Goupil, R; Stowasser, M, 2015) |
| "The aim of this study is to review the experience of the clonidine suppression test in a regional endocrine centre and to compare the diagnostic sensitivity and specificity using various previous published criteria." | 3.77 | Evaluation of the clonidine suppression test in the diagnosis of phaeochromocytoma. ( Atkinson, AB; Hunter, SJ; McCormick, MT; McHenry, CM; Russell, CF; Smye, MG, 2011) |
| "The clonidine test has been proposed as diagnostic biochemical test for patients with clinical suspicion of pheochromocytoma." | 3.71 | [Usefulness of the clonidine test for the diagnosis of pheochromocytoma]. ( Fernández-Torres, C; Hidalgo Tenorio, C; Jiménez-Alonso, J; León-Ruiz, L; López de la Torre Casares, M; Mediavilla García, JD; Piédrola Maroto, G; Pinel Julián, P, 2001) |
| "Phenelzine (PLZ), a nonselective monoamine oxidase inhibitor, is widely used in psychiatry for the treatment of panic disorder and depression." | 3.68 | Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: effects on monoamine oxidase, biogenic amines, and alpha 2-adrenoreceptor function. ( Baker, GB; Coutts, RT; Greenshaw, AJ; McKenna, KF, 1992) |
| "We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor." | 3.68 | Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991) |
| "Pheochromocytomas are catecholamine-producing tumors, representing one of the most important causes of secondary hypertension." | 2.40 | [Clinical and endocrine diagnosis of pheochromocytoma]. ( Kopf, D; Lehnert, H; Mundschenk, J; Schulz, C, 1997) |
| "Pheochromocytoma is mainly characterized by a great deal of variability in its biological activity and in its clinical manifestations." | 2.39 | [Diagnostic problems in pheochromocytoma]. ( Bellini, F; Ianni, L; Lanzillotti, R; Mannelli, M; Pupilli, C, 1995) |
| " Hence, study of the influence of ZJAHC on the pharmacokinetic behaviors of clonidine seems essential." | 1.42 | Development of an LC-MS/MS method for determining the pharmacokinetics of clonidine following oral administration of Zhenju antihypertensive compound. ( Chen, J; Han, L; Li, Y; Qin, J; Shen, T; Wang, J; Wang, L; Wu, L, 2015) |
| " Single application of tritiated water and [(14) C]-clonidine HCl were dosed at the same time on dermatomed human skin samples collected from 12 donors in a flow through diffusion cell system." | 1.38 | Ability to estimate relative percutaneous penetration via a surrogate maker - trans epidermal water loss? ( Chan, H; Elkeeb, R; Hui, X; Maibach, HI, 2012) |
| "Clonidine was extracted from human plasma by using solid-phase extraction technique." | 1.35 | Rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of clonidine in human plasma. ( Gomes, NA; Joshi, SS; Parekh, SA; Pudage, A; Vaidya, VV, 2008) |
| "Apraclonidine (0." | 1.33 | The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis. ( Acaroglu, G; Firat, E; Kansu, T; Kavuncu, S; Koc, F, 2005) |
| " The validated method has been successfully used to analyze human plasma samples for application in pharmacokinetic, bioavailability or bioequivalence studies." | 1.33 | Quantification of tizanidine in human plasma by liquid chromatography coupled to tandem mass spectrometry. ( Kandikere, VN; Maurya, S; Mudigonda, K; Nirogi, RV; Shukla, M, 2006) |
| "Clonidine was able to produce an analgesic effect but failed to provide maximal analgesia in all horses; the limited analgesic effect persisted for about 60 minutes." | 1.33 | Clonidine in horses: identification, detection, and clinical pharmacology. ( Dirikolu, L; ElkHoly, H; Ely, KJ; Lehner, AF; McFadden, ET; Thompson, K, 2006) |
| " The dose-response curve for phenylephrine-induced increases in mesenteric or hindlimb vascular resistance was shifted only 2- to 10-fold to the right by CEC." | 1.29 | The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat. ( Barron, KW; Piascik, MT; Smith, MS; Soltis, EE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (46.00) | 18.2507 |
| 2000's | 16 (32.00) | 29.6817 |
| 2010's | 10 (20.00) | 24.3611 |
| 2020's | 1 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonnard, C | 1 |
| Wirth, T | 1 |
| Gebus, O | 1 |
| Fahrer, P | 1 |
| Montaut, S | 1 |
| Robelin, L | 1 |
| Tuzin, N | 1 |
| Tranchant, C | 2 |
| Anheim, M | 2 |
| Alves Do Rego, C | 1 |
| Namer, IJ | 1 |
| Marcel, C | 1 |
| Lefebvre, F | 1 |
| Lagha-Boukbiza, O | 1 |
| Renaud, M | 1 |
| Qin, J | 1 |
| Wang, L | 1 |
| Wu, L | 1 |
| Chen, J | 2 |
| Shen, T | 1 |
| Li, Y | 1 |
| Han, L | 1 |
| Wang, J | 1 |
| Zhuang, J | 1 |
| Wang, X | 1 |
| Pang, Y | 1 |
| Bi, H | 1 |
| Huang, L | 1 |
| Zeng, G | 1 |
| Liao, X | 1 |
| Ma, Z | 1 |
| Chen, X | 1 |
| Zhong, G | 1 |
| Huang, M | 1 |
| Zhao, X | 1 |
| Goupil, R | 1 |
| Fountoulakis, S | 1 |
| Gordon, RD | 1 |
| Stowasser, M | 1 |
| Guzzetti, C | 1 |
| Ibba, A | 1 |
| Pilia, S | 1 |
| Beltrami, N | 1 |
| Di Iorgi, N | 1 |
| Rollo, A | 1 |
| Fratangeli, N | 1 |
| Radetti, G | 1 |
| Zucchini, S | 1 |
| Maghnie, M | 1 |
| Cappa, M | 1 |
| Loche, S | 1 |
| Nirogi, R | 1 |
| Kandikere, V | 1 |
| Mudigonda, K | 2 |
| Komarneni, P | 1 |
| Brusberg, M | 1 |
| Ravnefjord, A | 1 |
| Lindgreen, M | 1 |
| Larsson, H | 1 |
| Lindström, E | 1 |
| Martinez, V | 1 |
| Muster, L | 1 |
| Zangen, DH | 1 |
| Nesher, R | 1 |
| Hirsch, HJ | 1 |
| Muster, Z | 1 |
| Gillis, D | 1 |
| Henchoz, Y | 1 |
| Guillarme, D | 1 |
| Martel, S | 1 |
| Rudaz, S | 1 |
| Veuthey, JL | 1 |
| Carrupt, PA | 1 |
| Zhang, K | 1 |
| Zeng, Y | 1 |
| Song, C | 1 |
| Fu, Y | 1 |
| Wan, Q | 1 |
| McHenry, CM | 1 |
| Hunter, SJ | 1 |
| McCormick, MT | 1 |
| Russell, CF | 1 |
| Smye, MG | 1 |
| Atkinson, AB | 1 |
| Hui, X | 1 |
| Elkeeb, R | 1 |
| Chan, H | 1 |
| Maibach, HI | 1 |
| Yigiter, M | 1 |
| Yildiz, A | 1 |
| Polat, B | 1 |
| Alp, HH | 1 |
| Keles, ON | 1 |
| Salman, AB | 1 |
| Suleyman, H | 1 |
| Därr, R | 1 |
| Lenders, JW | 1 |
| Stange, K | 1 |
| Kindel, B | 1 |
| Hofbauer, LC | 1 |
| Bornstein, SR | 1 |
| Eisenhofer, G | 1 |
| Cianfarani, S | 1 |
| Tondinelli, T | 1 |
| Spadoni, GL | 1 |
| Scirè, G | 1 |
| Boemi, S | 1 |
| Boscherini, B | 1 |
| Shargorodsky, M | 1 |
| Zimlichman, R | 1 |
| Inubushi, M | 1 |
| Jordan, MC | 1 |
| Roos, KP | 1 |
| Ross, RS | 1 |
| Chatziioannou, AF | 1 |
| Stout, DB | 1 |
| Dahlbom, M | 1 |
| Schelbert, HR | 1 |
| Pellecchia, MT | 1 |
| Pivonello, R | 1 |
| Salvatore, E | 1 |
| Faggiano, A | 1 |
| Barone, P | 1 |
| De Michele, G | 1 |
| Lombardi, G | 1 |
| Colao, A | 1 |
| Filla, A | 1 |
| Koc, F | 1 |
| Kavuncu, S | 1 |
| Kansu, T | 1 |
| Acaroglu, G | 1 |
| Firat, E | 1 |
| Nirogi, RV | 1 |
| Kandikere, VN | 1 |
| Shukla, M | 1 |
| Maurya, S | 1 |
| Dirikolu, L | 1 |
| McFadden, ET | 1 |
| Ely, KJ | 1 |
| ElkHoly, H | 1 |
| Lehner, AF | 1 |
| Thompson, K | 1 |
| Hilczer, M | 1 |
| Smyczynska, J | 1 |
| Lewinski, A | 1 |
| Müller, C | 1 |
| Ramic, M | 1 |
| Harlfinger, S | 1 |
| Hünseler, C | 1 |
| Theisohn, M | 1 |
| Roth, B | 1 |
| Parekh, SA | 1 |
| Pudage, A | 1 |
| Joshi, SS | 1 |
| Vaidya, VV | 1 |
| Gomes, NA | 1 |
| Satoh, M | 1 |
| Kokubu, N | 1 |
| Matsuo, K | 1 |
| Takayanagi, I | 1 |
| Mannelli, M | 1 |
| Pupilli, C | 1 |
| Lanzillotti, R | 1 |
| Ianni, L | 1 |
| Bellini, F | 1 |
| Nardecchia, A | 1 |
| Turturro, N | 1 |
| Noviello, F | 1 |
| Vernaglione, L | 1 |
| Pirrelli, A | 1 |
| Allgaier, C | 1 |
| Schobert, A | 1 |
| Belledin, M | 1 |
| Jackisch, R | 1 |
| Hertting, G | 1 |
| Courteix, C | 1 |
| Bardin, M | 1 |
| Chantelauze, C | 1 |
| Lavarenne, J | 1 |
| Eschalier, A | 1 |
| Rochiccioli, P | 1 |
| Enjaume, C | 1 |
| Tauber, MT | 1 |
| Pienkowski, C | 1 |
| Oliver, I | 1 |
| Piascik, MT | 1 |
| Smith, MS | 1 |
| Barron, KW | 1 |
| Soltis, EE | 1 |
| Schubert, T | 1 |
| Stoll, L | 1 |
| Fleckenstein, P | 1 |
| Riemann, D | 1 |
| Berger, M | 1 |
| Müller, WE | 1 |
| Fernández-Galaz, C | 1 |
| Herbison, AE | 1 |
| Dyer, RG | 1 |
| Maszak, G | 1 |
| Becker, K | 1 |
| Conway, S | 1 |
| Høier, R | 1 |
| Jensen, AL | 1 |
| Iversen, L | 1 |
| Rivero Marcotegui, A | 1 |
| Grijalba Uche, A | 1 |
| Palacios Sarrasqueta, M | 1 |
| Garcia Merlo, S | 1 |
| Chieng, B | 1 |
| Christie, MD | 1 |
| Juul, A | 1 |
| Skakkebaek, NE | 1 |
| Durá Travé, T | 1 |
| Juste Ruiz, M | 1 |
| González Montero, R | 1 |
| Gutiérrez Terán, M | 1 |
| Mauri Dot, M | 1 |
| Moya Benavent, M | 1 |
| Bol, CJ | 1 |
| IJzerman, AP | 1 |
| Danhof, M | 1 |
| Mandema, JW | 1 |
| Lehnert, H | 1 |
| Schulz, C | 1 |
| Mundschenk, J | 1 |
| Kopf, D | 1 |
| Pellini, C | 1 |
| De Angelis, R | 1 |
| di Natale, B | 1 |
| Lukezic, M | 1 |
| Mora, S | 1 |
| Chiumello, G | 1 |
| Lenz, T | 1 |
| Ross, A | 1 |
| Schumm-Draeger, P | 1 |
| Schulte, KL | 1 |
| Geiger, H | 1 |
| Alvarez-Guerra, M | 1 |
| Bertholom, N | 1 |
| Garay, RP | 1 |
| Shiga, M | 1 |
| Nishina, K | 1 |
| Mikawa, K | 1 |
| Uesugi, T | 1 |
| Maekawa, N | 1 |
| Obara, H | 1 |
| Mediavilla García, JD | 1 |
| León-Ruiz, L | 1 |
| Hidalgo Tenorio, C | 1 |
| López de la Torre Casares, M | 1 |
| Piédrola Maroto, G | 1 |
| Pinel Julián, P | 1 |
| Fernández-Torres, C | 1 |
| Jiménez-Alonso, J | 1 |
| McKenna, KF | 1 |
| Baker, GB | 1 |
| Coutts, RT | 1 |
| Greenshaw, AJ | 1 |
| Julius, S | 1 |
| Grossman, E | 1 |
| Goldstein, DS | 1 |
| Hoffman, A | 1 |
| Keiser, HR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnosis and Treatment of Pheochromocytoma[NCT00001229] | 240 participants | Observational | 1988-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for clonidine and Sensitivity and Specificity
| Article | Year |
|---|---|
[Diagnostic problems in pheochromocytoma].
Topics: 3-Iodobenzylguanidine; Adrenal Cortex Neoplasms; Algorithms; Biomarkers; Catecholamines; Clonidine; | 1995 |
[Laboratory contribution to the diagnosis of pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Biochemical Phenomena; Biochemistry; Biomarkers; Catecholamines; Chromatogr | 1996 |
[Clinical and endocrine diagnosis of pheochromocytoma].
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Catecholamines; Clonidine; Humans; Iodine Radioisoto | 1997 |
Clonidine suppression test revisited.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Clonidine; Creatinine; Epinephrine; Female; Hemodynamics; Huma | 1998 |
5 trials available for clonidine and Sensitivity and Specificity
| Article | Year |
|---|---|
The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease.
Topics: Aged; Arginine; Clonidine; Diagnosis, Differential; Drug Combinations; Female; Human Growth Hormone; | 2010 |
Limitations of clinical utility of growth hormone stimulating tests in diagnosing children with short stature.
Topics: Adolescent; Child; Clonidine; Diagnostic Errors; False Negative Reactions; Female; Glucagon; Growth | 2006 |
[Sensitivity of the clonidine and guanfacine tests (alpha-2-adrenergic agonists) as pharmacologic stimulants of growth hormone. Effects on plasma cortisol].
Topics: Adrenergic alpha-Agonists; Child; Clonidine; Female; Growth Disorders; Guanfacine; Human Growth Horm | 1996 |
Oral clonidine premedication does not change efficacy of simulated epidural test dose in sevoflurane-anesthetized children.
Topics: Administration, Oral; Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Anal | 2000 |
Home blood pressure monitoring: advantages and limitations.
Topics: Blood Pressure Determination; Clonidine; Coronary Disease; Double-Blind Method; Humans; Hypertension | 1991 |
41 other studies available for clonidine and Sensitivity and Specificity
| Article | Year |
|---|---|
Clonidine GH stimulation test to differentiate MSA from idiopathic late onset cerebellar ataxia: a prospective, controlled study.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Clonidine; Diagnosis, Differential; Early Diagnosis; Fem | 2020 |
Prospective study of relevance of
Topics: 3-Iodobenzylguanidine; Biomarkers; Clonidine; Diagnosis, Differential; Female; Follow-Up Studies; He | 2018 |
Development of an LC-MS/MS method for determining the pharmacokinetics of clonidine following oral administration of Zhenju antihypertensive compound.
Topics: Animals; Antihypertensive Agents; Chromatography, Liquid; Clonidine; Drugs, Chinese Herbal; Linear M | 2015 |
Validation of a HPLC-ESI MS/MS method for the determination of clonidine in human plasma and its application in a bioequivalence study in Chinese healthy volunteers.
Topics: Adult; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Clonidine; Healthy Volun | 2015 |
Urinary clonidine suppression testing for the diagnosis of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Clonidine; Female; Humans; Male; Metanephrine; Middl | 2015 |
Cut-off limits of the peak GH response to stimulation tests for the diagnosis of GH deficiency in children and adolescents: study in patients with organic GHD.
Topics: Adolescent; Arginine; Child; Clonidine; Female; Human Growth Hormone; Humans; Hypopituitarism; Insul | 2016 |
Liquid chromatography tandem mass spectrometry method for the quantification of clonidine with LLOQ of 10 pg/mL in human plasma.
Topics: Antihypertensive Agents; Chromatography, High Pressure Liquid; Clonidine; Humans; Sensitivity and Sp | 2008 |
Oral clonidine inhibits visceral pain-related viscerosomatic and cardiovascular responses to colorectal distension in rats.
Topics: Abdominal Pain; Analgesics; Animals; Blood Pressure; Clonidine; Colonic Diseases; Dilatation, Pathol | 2008 |
Arginine and clonidine stimulation tests for growth hormone deficiency revisited--do we really need so many samples?
Topics: Adolescent; Arginine; Child; Child, Preschool; Clonidine; Diagnostic Techniques, Endocrine; Female; | 2009 |
Fast log P determination by ultra-high-pressure liquid chromatography coupled with UV and mass spectrometry detections.
Topics: Adrenergic beta-Antagonists; Anesthetics; Chromatography, High Pressure Liquid; Clonidine; Mass Spec | 2009 |
Evaluation of the clonidine suppression test in the diagnosis of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Catecholamines; Clonidine; Diagnostic Tests, Routi | 2011 |
Ability to estimate relative percutaneous penetration via a surrogate maker - trans epidermal water loss?
Topics: Biomarkers; Body Water; Carbon Radioisotopes; Clonidine; Humans; Radioisotope Dilution Technique; Re | 2012 |
The protective effects of metyrosine, lacidipine, clonidine, and moxonidine on kidney damage induced by unilateral ureteral obstruction in rats.
Topics: Acute Kidney Injury; alpha-Methyltyrosine; Animals; Biopsy, Needle; Clonidine; Dihydropyridines; Dis | 2012 |
[Diagnosis of pheochromocytoma and paraganglioma: the clonidine suppression test in patients with borderline elevations of plasma free normetanephrine].
Topics: Adrenal Gland Neoplasms; Adult; Aged; Biomarkers; Clonidine; Female; Humans; Male; Middle Aged; Norm | 2013 |
Height velocity and IGF-I assessment in the diagnosis of childhood onset GH insufficiency: do we still need a second GH stimulation test?
Topics: Arginine; Body Height; Child; Clonidine; Female; Growth Disorders; Growth Hormone; Growth Hormone-Re | 2002 |
Pheochromocytoma: a disease with many faces.
Topics: Adrenal Gland Neoplasms; Catecholamines; Chromatography, High Pressure Liquid; Clonidine; Diagnosis, | 2002 |
Nitrogen-13 ammonia cardiac positron emission tomography in mice: effects of clonidine-induced changes in cardiac work on myocardial perfusion.
Topics: Ammonia; Animals; Clonidine; Coronary Circulation; Coronary Vessels; Feasibility Studies; Heart; Hea | 2004 |
Growth hormone response to arginine test distinguishes multiple system atrophy from Parkinson's disease and idiopathic late-onset cerebellar ataxia.
Topics: Arginine; Case-Control Studies; Clonidine; Diagnosis, Differential; Female; Growth Hormone; Growth H | 2005 |
The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis.
Topics: Adrenergic alpha-Agonists; Adult; Anisocoria; Blepharoptosis; Clonidine; Diabetic Neuropathies; Fema | 2005 |
Quantification of tizanidine in human plasma by liquid chromatography coupled to tandem mass spectrometry.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Clonidine; Humans; Reproducibility of | 2006 |
Clonidine in horses: identification, detection, and clinical pharmacology.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Doping in S | 2006 |
Sensitive and convenient method for the quantification of clonidine in serum of pediatric patients using liquid chromatography/tandem mass spectrometry.
Topics: Child; Chromatography, Liquid; Clonidine; Humans; Patients; Sensitivity and Specificity; Tandem Mass | 2007 |
Rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of clonidine in human plasma.
Topics: Adrenergic alpha-Agonists; Calibration; Chromatography, Liquid; Clonidine; Humans; Reference Standar | 2008 |
Alpha 1A-adrenoceptor subtype effectively increases Ca(2+)-sensitivity for contraction in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Aorta, Thoracic; Calciu | 1995 |
Positive responses to clonidine test in nephrovascular hypertension: only a false positive?
Topics: Adrenal Gland Neoplasms; Adult; Clonidine; False Positive Reactions; Female; Humans; Hyperaldosteron | 1994 |
Modulation of electrically evoked [3H]-noradrenaline release from cultured chick sympathetic neurons.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channels; Cells, Cultured | 1994 |
Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Aspirin; Clonidine; Diabetes Mellitus, Experi | 1994 |
[Statistic study of 5,473 somatotropin secretion stimulation pharmacologic tests (n=9). Proposed weighting coefficient].
Topics: Adolescent; Age Determination by Skeleton; Arginine; Betaxolol; Child; Child, Preschool; Clonidine; | 1993 |
The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat.
Topics: Animals; Blood Pressure; Clonidine; Consciousness; Drug Resistance; Hemodynamics; Hindlimb; Male; Me | 1993 |
Effects of single and repeated clonidine administration on the properties of central and peripheral alpha 2-adrenoceptors in man.
Topics: Adaptation, Physiological; Adult; Animals; Blood Platelets; Brain; Clonidine; Female; Growth Hormone | 1993 |
Characterization of tritiated noradrenaline release from the rat preoptic area with microdialysis in vivo.
Topics: Animals; Autoradiography; Chromatography, High Pressure Liquid; Clonidine; Culture Media; Dialysis; | 1993 |
The development of sexually dimorphic sensitivity to growth hormone (GH) feedback of the clonidine-induced GH surge in the rat.
Topics: Age Factors; Animals; Clonidine; Feedback; Female; Growth Hormone; Male; Radioimmunoassay; Rats; Rat | 1995 |
An improved radioimmunoassay for the determination of canine growth hormone based on commercially available reagents.
Topics: Acromegaly; Animals; Antibodies; Clonidine; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Growth | 1995 |
Local opioid withdrawal in rat single periaqueductal gray neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclof | 1996 |
Prediction of the outcome of growth hormone provocative testing in short children by measurement of serum levels of insulin-like growth factor I and insulin-like growth factor binding protein 3.
Topics: Adolescent; Arginine; Biomarkers; Body Height; Child; Child, Preschool; Clonidine; Denmark; Female; | 1997 |
Determination of dexmedetomidine in rat plasma by a sensitive [3H]clonidine radioreceptor assay.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anima | 1997 |
Dexamethasone in the diagnostic work-up of growth hormone deficiency.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Area Under Curve; Child; Child, Prescho | 1998 |
Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1999 |
[Usefulness of the clonidine test for the diagnosis of pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Clonidine; Female; Humans; Male; Middle Aged; Pheoch | 2001 |
Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: effects on monoamine oxidase, biogenic amines, and alpha 2-adrenoreceptor function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Biogenic Amines; Body Weight; Brain; | 1992 |
Glucagon and clonidine testing in the diagnosis of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Catechols; Clonidine; Drug Therapy, Combination; Glucagon; Humans; Hyperten | 1991 |