metoprolol has been researched along with Sensitivity and Specificity in 58 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate neurohumoral factors as markers for left-ventricular (LV) antiremodelling from metoprolol treatment in patients with chronic LV systolic heart failure." | 9.10 | Neurohumoral prediction of left-ventricular morphologic response to beta-blockade with metoprolol in chronic left-ventricular systolic heart failure. ( Fritz-Hansen, T; Groenning, BA; Hildebrandt, PR; Kjaer, A; Larsson, HB; Nilsson, JC; Sondergaard, L, 2002) |
| "We studied the value of a rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography (DASE) for the detection of coronary artery disease (CAD)." | 7.72 | Value of rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography for detection of coronary artery disease. ( Andrade, JL; Khandheria, BK; Kowatsch, I; Leal, SM; Lemos, PA; Mathias, W; Ramires, JF; Tsutsui, JM, 2003) |
| "To evaluate neurohumoral factors as markers for left-ventricular (LV) antiremodelling from metoprolol treatment in patients with chronic LV systolic heart failure." | 5.10 | Neurohumoral prediction of left-ventricular morphologic response to beta-blockade with metoprolol in chronic left-ventricular systolic heart failure. ( Fritz-Hansen, T; Groenning, BA; Hildebrandt, PR; Kjaer, A; Larsson, HB; Nilsson, JC; Sondergaard, L, 2002) |
| " The curative effect of metoprolol tartrate and valsartan in reversing left ventricular hypertrophy in the group positive for autoantibodies was much better than in the negative group." | 3.80 | Autoantibodies against β1 receptor and AT1 receptor in type 2 diabetes patients with left ventricular dilatation. ( Xu, C; Xu, J; Zhao, L, 2014) |
| "To investigate whether heart rate reduction via I(f)-channel blockade and β-receptor blockade prevents left ventricular (LV) dysfunction, we studied ivabradine and metoprolol in angiotensin II-induced heart failure." | 3.78 | Role of heart rate reduction in the prevention of experimental heart failure: comparison between If-channel blockade and β-receptor blockade. ( Becher, PM; Lindner, D; Miteva, K; Savvatis, K; Schmack, B; Schultheiss, HP; Tschöpe, C; Van Linthout, S; Westermann, D; Zietsch, C, 2012) |
| "We studied the value of a rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography (DASE) for the detection of coronary artery disease (CAD)." | 3.72 | Value of rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography for detection of coronary artery disease. ( Andrade, JL; Khandheria, BK; Kowatsch, I; Leal, SM; Lemos, PA; Mathias, W; Ramires, JF; Tsutsui, JM, 2003) |
| " As the management of drug-drug interactions (DDIs) constitutes a key aspect of the care of PLWH, the magnitude of pharmacokinetic DDIs between cardiovascular and anti-HIV drugs needs to be more thoroughly characterized." | 1.51 | UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV. ( Alves Saldanha, S; Buclin, T; Cavassini, M; Courlet, P; Csajka, C; Decosterd, LA; Desfontaine, V; Marzolini, C; Spaggiari, D, 2019) |
| "Fluoxetine was found to be enriched with S(+)-enantiomer, which is more toxic to P." | 1.39 | Multi-residue enantiomeric analysis of pharmaceuticals and their active metabolites in the Guadalquivir River basin (South Spain) by chiral liquid chromatography coupled with tandem mass spectrometry. ( Barceló, D; Kasprzyk-Hordern, B; López-Serna, R; Petrović, M, 2013) |
| "Metoprolol recovery was determined at 73." | 1.33 | HPLC quantification of metoprolol with solid-phase extraction for the drug monitoring of pediatric patients. ( Albers, S; Elshoff, JP; Läer, S; Richter, A; Völker, C, 2005) |
| "With appropriate protocol, MDCT is safe and accurate in assessing the severity of IRA and the number of diseased vessels during the first week after AMI." | 1.33 | Safety and accuracy of multidetector row computed tomography for early assessment of residual stenosis of the infarct-related artery and the number of diseased vessels after acute myocardial infarction. ( Chiou, KR; Hsiao, SH; Liu, CP; Mar, GY; Pan, HB; Wu, MT; Yang, CF, 2005) |
| " The confident limits show that the methods are compatible with pharmacokinetic investigations of the enantioselective metabolism of metoprolol." | 1.32 | Enantioselective determination of metoprolol acidic metabolite in plasma and urine using liquid chromatography chiral columns: applications to pharmacokinetics. ( Bonato, PS; Boralli, VB; Cerqueira, PM; Coelho, EB; Guimarães, LF; Lanchote, VL; Lopes, NP, 2003) |
| " It has been applied to the determination of (R)-(+)-metoprolol and (S)-(-)-metoprolol in urine from healthy volunteers dosed with racemic metoprolol tartrate." | 1.31 | Determination of metoprolol enantiomers in human urine by coupled achiral-chiral chromatography. ( Kang, JS; Kim, HJ; Kim, KH; Mar, W, 2000) |
| " The methods were employed to determine plasma concentrations of metoprolol enantiomers in a pharmacokinetic study of single dose administration of racemic metoprolol to a healthy Caucasian volunteer phenotyped as extensive metabolizer of debrisoquine." | 1.31 | Enantioselective analysis of metoprolol in plasma using high-performance liquid chromatographic direct and indirect separations: applications in pharmacokinetics. ( Bonato, PS; Cerqueira, PM; Cesarino, EJ; Lanchote, VL; Pereira, VA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (12.07) | 18.2507 |
| 2000's | 36 (62.07) | 29.6817 |
| 2010's | 11 (18.97) | 24.3611 |
| 2020's | 4 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Sun, J | 2 |
| Sui, X | 1 |
| Liu, J | 1 |
| Yan, Z | 1 |
| Liu, X | 1 |
| Sun, Y | 1 |
| He, Z | 1 |
| Wang, J | 1 |
| Li, C | 2 |
| Li, P | 1 |
| Xu, BW | 1 |
| Zhang, QY | 1 |
| Li, XY | 1 |
| Tang, CS | 1 |
| Du, JB | 1 |
| Liu, XQ | 1 |
| Jin, HF | 1 |
| Wang, S | 1 |
| Zou, R | 1 |
| Cai, H | 1 |
| Wang, Y | 1 |
| Ding, Y | 1 |
| Tan, C | 1 |
| Yang, M | 1 |
| Li, F | 1 |
| Wang, C | 1 |
| Li, N | 2 |
| He, S | 1 |
| Yang, F | 1 |
| Dong, Y | 1 |
| Courlet, P | 1 |
| Spaggiari, D | 1 |
| Desfontaine, V | 1 |
| Cavassini, M | 1 |
| Alves Saldanha, S | 1 |
| Buclin, T | 1 |
| Marzolini, C | 1 |
| Csajka, C | 1 |
| Decosterd, LA | 1 |
| Zoerner, AA | 1 |
| Schroeder, C | 1 |
| Kayacelebi, AA | 1 |
| Suchy, MT | 1 |
| Gutzki, FM | 1 |
| Stichtenoth, DO | 1 |
| Tank, J | 1 |
| Jordan, J | 1 |
| Tsikas, D | 1 |
| López-Serna, R | 1 |
| Kasprzyk-Hordern, B | 1 |
| Petrović, M | 1 |
| Barceló, D | 1 |
| Riml, J | 1 |
| Wörman, A | 1 |
| Kunkel, U | 1 |
| Radke, M | 1 |
| Xu, T | 1 |
| Bao, S | 1 |
| Geng, P | 1 |
| Luo, J | 1 |
| Yu, L | 1 |
| Pan, P | 1 |
| Chen, Y | 1 |
| Hu, G | 1 |
| Li, CL | 1 |
| Lu, NW | 1 |
| Dong, YM | 1 |
| Zhao, L | 1 |
| Xu, C | 1 |
| Xu, J | 2 |
| Cesari, M | 1 |
| Mehlsen, J | 1 |
| Mehlsen, AB | 1 |
| Dissing Sorensen, HB | 1 |
| Sarkar, AK | 1 |
| Ghosh, D | 1 |
| Das, A | 1 |
| Selvan, PS | 1 |
| Gowda, KV | 1 |
| Mandal, U | 1 |
| Bose, A | 1 |
| Agarwal, S | 1 |
| Bhaumik, U | 1 |
| Pal, TK | 1 |
| Zhang, X | 2 |
| Yang, L | 1 |
| Zhai, S | 1 |
| Duan, J | 1 |
| Quirino, JP | 1 |
| Liu, W | 1 |
| Zhang, L | 1 |
| Wei, Z | 1 |
| Chen, S | 1 |
| Chen, G | 1 |
| Baranowska, I | 1 |
| Wilczek, A | 1 |
| Yilmaz, B | 1 |
| Asci, A | 1 |
| Arslan, S | 1 |
| Becher, PM | 1 |
| Lindner, D | 1 |
| Miteva, K | 1 |
| Savvatis, K | 1 |
| Zietsch, C | 1 |
| Schmack, B | 1 |
| Van Linthout, S | 1 |
| Westermann, D | 1 |
| Schultheiss, HP | 1 |
| Tschöpe, C | 1 |
| Liu, Y | 1 |
| Li, X | 1 |
| Yang, C | 1 |
| Tai, S | 1 |
| Liu, G | 1 |
| Kasama, S | 1 |
| Toyama, T | 1 |
| Hoshizaki, H | 1 |
| Oshima, S | 1 |
| Taniguchi, K | 1 |
| Suzuki, T | 1 |
| Kurabayashi, M | 1 |
| Groenning, BA | 1 |
| Nilsson, JC | 1 |
| Hildebrandt, PR | 1 |
| Kjaer, A | 1 |
| Fritz-Hansen, T | 1 |
| Larsson, HB | 1 |
| Sondergaard, L | 1 |
| Cerqueira, PM | 2 |
| Boralli, VB | 1 |
| Coelho, EB | 1 |
| Lopes, NP | 1 |
| Guimarães, LF | 1 |
| Bonato, PS | 2 |
| Lanchote, VL | 2 |
| Gyllenhaal, O | 1 |
| Karlsson, A | 1 |
| Scharhag, J | 1 |
| Meyer, T | 1 |
| Görge, G | 1 |
| Kindermann, W | 1 |
| Mathias, W | 1 |
| Tsutsui, JM | 1 |
| Andrade, JL | 1 |
| Kowatsch, I | 1 |
| Lemos, PA | 1 |
| Leal, SM | 1 |
| Khandheria, BK | 1 |
| Ramires, JF | 1 |
| Hassan, SS | 1 |
| Abou-Sekkina, MM | 1 |
| El-Ries, MA | 1 |
| Wassel, A | 1 |
| Fang, J | 1 |
| Semple, HA | 1 |
| Song, J | 1 |
| Albers, S | 1 |
| Elshoff, JP | 1 |
| Völker, C | 1 |
| Richter, A | 1 |
| Läer, S | 1 |
| Zhang, ZX | 1 |
| He, YZ | 1 |
| Salo, PK | 1 |
| Salomies, H | 1 |
| Harju, K | 1 |
| Ketola, RA | 1 |
| Kotiaho, T | 1 |
| Yli-Kauhaluoma, J | 1 |
| Kostiainen, R | 1 |
| Chiou, KR | 1 |
| Wu, MT | 1 |
| Hsiao, SH | 1 |
| Mar, GY | 1 |
| Pan, HB | 1 |
| Yang, CF | 1 |
| Liu, CP | 1 |
| Rahman, N | 1 |
| Rahman, H | 1 |
| Azmi, SN | 1 |
| Chawla, S | 1 |
| Ghosh, S | 1 |
| Sihorkar, V | 1 |
| Nellore, R | 1 |
| Kumar, TR | 1 |
| Srinivas, NR | 1 |
| Dong, J | 1 |
| Xie, C | 1 |
| Tian, R | 1 |
| Wu, R | 1 |
| Hu, J | 1 |
| Zou, H | 1 |
| Angier, MK | 1 |
| Lewis, RJ | 1 |
| Chaturvedi, AK | 1 |
| Canfield, DV | 1 |
| Yao, J | 1 |
| Lu, FX | 1 |
| Xu, D | 1 |
| Zhou, L | 1 |
| Yong, YH | 1 |
| Tang, XX | 1 |
| Karagiannis, SE | 1 |
| Bax, JJ | 1 |
| Elhendy, A | 1 |
| Feringa, HH | 1 |
| Cokkinos, DV | 1 |
| van Domburg, R | 1 |
| Simoons, M | 1 |
| Poldermans, D | 1 |
| Huang, J | 1 |
| Zhou, X | 1 |
| You, T | 1 |
| Johansson, T | 1 |
| Weidolf, L | 1 |
| Jurva, U | 1 |
| Umezawa, H | 1 |
| Lee, XP | 1 |
| Arima, Y | 1 |
| Hasegawa, C | 1 |
| Izawa, H | 1 |
| Kumazawa, T | 1 |
| Sato, K | 1 |
| Bjorkander, I | 1 |
| Forslund, L | 1 |
| Kahan, T | 1 |
| Ericson, M | 1 |
| Held, C | 1 |
| Rehnqvist, N | 1 |
| Hjemdahl, P | 1 |
| Fernandez, AR | 1 |
| Sequeira, RF | 1 |
| Chakko, S | 1 |
| Correa, LF | 1 |
| de Marchena, EJ | 1 |
| Chahine, RA | 1 |
| Franceour, DA | 1 |
| Myerburg, RJ | 1 |
| Yamada, T | 1 |
| Fukunami, M | 1 |
| Ohmori, M | 1 |
| Iwakura, K | 1 |
| Kumagai, K | 1 |
| Kondoh, N | 1 |
| Minamino, T | 1 |
| Tsujimura, E | 1 |
| Nagareda, T | 1 |
| Kotoh, K | 1 |
| Mangani, F | 1 |
| Luck, G | 1 |
| Fraudeau, C | 1 |
| Vérette, E | 1 |
| Chiu, FC | 1 |
| Damani, LA | 1 |
| Li, RC | 1 |
| Tomlinson, B | 1 |
| Weissman, NJ | 1 |
| Sheris, SJ | 1 |
| Picard, MH | 1 |
| Bach, DS | 1 |
| Sklar, J | 1 |
| Cohen, JL | 1 |
| Fente, CA | 1 |
| Vázquez, BI | 1 |
| Franco, C | 1 |
| Cepeda, A | 1 |
| Gigosos, PG | 1 |
| Kim, KH | 2 |
| Choi, PW | 1 |
| Hong, SP | 1 |
| Kim, HJ | 2 |
| Kang, JS | 1 |
| Mar, W | 1 |
| Pereira, VA | 1 |
| Cesarino, EJ | 1 |
| Durkin, D | 1 |
| Foley, JP | 1 |
| Gregory, D | 1 |
| Udelson, JE | 1 |
| Konstam, MA | 1 |
| Mistry, B | 1 |
| Leslie, JL | 1 |
| Eddington, ND | 1 |
| Ito, T | 1 |
| Hoshida, S | 1 |
| Nishino, M | 1 |
| Aoi, T | 1 |
| Egami, Y | 1 |
| Takeda, T | 1 |
| Kawabata, M | 1 |
| Tanouchi, J | 1 |
| Yamada, Y | 1 |
| Kamada, T | 1 |
| Zaglavara, T | 1 |
| Haaverstad, R | 1 |
| Cumberledge, B | 1 |
| Irvine, T | 1 |
| Karvounis, H | 1 |
| Parharidis, G | 1 |
| Louridas, G | 1 |
| Kenny, A | 1 |
| de Milliano, PA | 1 |
| Tijssen, JG | 1 |
| van Eck-Smit, BL | 1 |
| Lie, KI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Einfluss Selektiver I(f)-Blockade Auf Orthostase-Toleranz Und Sympathikusaktivität Bei Gesunden[NCT00865917] | Phase 2 | 40 participants (Anticipated) | Interventional | 2008-11-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for metoprolol and Sensitivity and Specificity
| Article | Year |
|---|---|
Economic impact of beta blockade in heart failure.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Cost-Bene | 2001 |
5 trials available for metoprolol and Sensitivity and Specificity
| Article | Year |
|---|---|
Neurohumoral prediction of left-ventricular morphologic response to beta-blockade with metoprolol in chronic left-ventricular systolic heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Biological Factors; Biomarkers; Blood P | 2002 |
Differential index: a simple time domain heart rate variability analysis with prognostic implications in stable angina pectoris.
Topics: Aged; Angina Pectoris; Cause of Death; Dose-Response Relationship, Drug; Double-Blind Method; Drug A | 2008 |
ST segment tracking for rapid determination of patency of the infarct-related artery in acute myocardial infarction.
Topics: Anistreplase; Cardiac Catheterization; Confidence Intervals; Coronary Angiography; Coronary Disease; | 1995 |
Effect of atenolol or metoprolol on arbutamine stress echocardiography in patients suspected of having coronary artery disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Coronary Disease; Echocardiography; Exercise Test; Female; He | 1998 |
Cardiac 123 I-MIBG imaging and clinical variables in risk stratification in patients with heart failure treated with beta blockers.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Aged; Female; Follow-Up Studies; Heart Failure; | 2002 |
52 other studies available for metoprolol and Sensitivity and Specificity
| Article | Year |
|---|---|
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metab | 2009 |
A Small Footprint and Robust Interface for Solid Phase Microextraction and Mass Spectrometry Based on Vibrating Sharp-Edge Spray Ionization.
Topics: Carbamazepine; Equipment Design; Limit of Detection; Metoprolol; Pindolol; Sensitivity and Specifici | 2022 |
A predictive model of response to metoprolol in children and adolescents with postural tachycardia syndrome.
Topics: Adolescent; Child; Heart Rate; Humans; Metoprolol; Postural Orthostatic Tachycardia Syndrome; ROC Cu | 2023 |
Heart Rate and Heart Rate Difference Predicted the Efficacy of Metoprolol on Postural Tachycardia Syndrome in Children and Adolescents.
Topics: Adrenergic beta-1 Receptor Antagonists; Case-Control Studies; Child; Female; Heart Rate; Humans; Mal | 2020 |
Sensitive Analysis of Metoprolol Tartrate and Diltiazem Hydrochloride in Human Serum by Capillary Zone Electrophoresis Combining on Column Field-Amplified Sample Injection.
Topics: Diltiazem; Electrophoresis, Capillary; Humans; Limit of Detection; Linear Models; Metoprolol; Reprod | 2021 |
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Topics: Amlodipine; Anti-HIV Agents; Atorvastatin; Chromatography, High Pressure Liquid; Drug Interactions; | 2019 |
A validated, rapid UPLC-MS/MS method for simultaneous ivabradine, reboxetine, and metoprolol analysis in human plasma and its application to clinical trial samples.
Topics: Benzazepines; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Drug St | 2013 |
Multi-residue enantiomeric analysis of pharmaceuticals and their active metabolites in the Guadalquivir River basin (South Spain) by chiral liquid chromatography coupled with tandem mass spectrometry.
Topics: Atenolol; Chromatography, Liquid; Environmental Monitoring; Fluoxetine; Metoprolol; Pharmaceutical P | 2013 |
Evaluating the fate of six common pharmaceuticals using a reactive transport model: insights from a stream tracer test.
Topics: Adsorption; Bezafibrate; Chromatography, High Pressure Liquid; Clofibric Acid; Ibuprofen; Metoprolol | 2013 |
Determination of metoprolol and its two metabolites in human plasma and urine by high performance liquid chromatography with fluorescence detection and its application in pharmacokinetics.
Topics: Chromatography, High Pressure Liquid; Humans; Linear Models; Metoprolol; Reproducibility of Results; | 2013 |
A novel micellar per aqueous liquid chromatographic method for simultaneous determination of diltiazem hydrochloride, metoprolol tartrate and isosorbide mononitrate in human serum.
Topics: Chromatography, Liquid; Diltiazem; Drug Stability; Humans; Hydrogen-Ion Concentration; Isosorbide Di | 2014 |
Autoantibodies against β1 receptor and AT1 receptor in type 2 diabetes patients with left ventricular dilatation.
Topics: Aged; Antihypertensive Agents; Autoantibodies; Biomarkers; Diabetes Mellitus, Type 2; Dilatation, Pa | 2014 |
Application of a new robust ECG T-wave delineation algorithm for the evaluation of the autonomic innervation of the myocardium.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Algorithms; Atropine; Autonomic Nervous System; Datab | 2016 |
Simultaneous determination of metoprolol succinate and amlodipine besylate in human plasma by liquid chromatography-tandem mass spectrometry method and its application in bioequivalence study.
Topics: Amlodipine; Chromatography, Liquid; Drug Stability; Metoprolol; Reproducibility of Results; Sensitiv | 2008 |
Simultaneous quantification of tiloronoxim and tilorone in human urine by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Humans; Linear Models; Male; Metoprolol; Oximes; Reference Standards; Sensit | 2008 |
Micelle to solvent stacking of organic cations in capillary zone electrophoresis with electrospray ionization mass spectrometry.
Topics: Acetonitriles; Adrenergic beta-Antagonists; Cations; Electrophoresis, Capillary; Linear Models; Meth | 2009 |
Analysis of beta-agonists and beta-blockers in urine using hollow fibre-protected liquid-phase microextraction with in situ derivatization followed by gas chromatography/mass spectrometry.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Chemical Fractionation; Clenbuterol; Gas Chro | 2009 |
Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine.
Topics: Chromatography, High Pressure Liquid; Glucuronides; Humans; Metoprolol; Molecular Structure; Reprodu | 2009 |
Determination of metoprolol in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
Topics: Adult; Calibration; Chromatography, High Pressure Liquid; Fluorescence; Humans; Linear Models; Metop | 2010 |
Role of heart rate reduction in the prevention of experimental heart failure: comparison between If-channel blockade and β-receptor blockade.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II; Animals; Apoptosis; Benzazepines; Cyclic Nuc | 2012 |
UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dapsone; Dr | 2013 |
Dobutamine gated blood pool scintigraphy predicts the improvement of cardiac sympathetic nerve activity, cardiac function, and symptoms after treatment in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardio | 2002 |
Enantioselective determination of metoprolol acidic metabolite in plasma and urine using liquid chromatography chiral columns: applications to pharmacokinetics.
Topics: Adrenergic beta-Antagonists; Area Under Curve; Chromatography, High Pressure Liquid; Humans; Metopro | 2003 |
Enantiomeric separations of amino alcohols by packed-column SFC on Hypercarb with L-(+)-tartaric acid as chiral selector.
Topics: Amino Alcohols; Chromatography, Supercritical Fluid; Graphite; Metoprolol; Models, Chemical; Quality | 2002 |
[Competitive sports and dilated cardiomyopathy: the case of a 32-year-old soccer player with ventricular tachycardia].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents | 2003 |
Value of rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography for detection of coronary artery disease.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atropine; Coronary Artery Disease; Echoca | 2003 |
Polymeric matrix membrane sensors for sensitive potentiometric determination of some beta-blockers in pharmaceutical preparations.
Topics: Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Indicators and Reagents; Ions; Metoprolol; Phosph | 2003 |
Determination of metoprolol, and its four metabolites in dog plasma.
Topics: Adrenergic beta-Antagonists; Animals; Chromatography, High Pressure Liquid; Dogs; Female; Metoprolol | 2004 |
HPLC quantification of metoprolol with solid-phase extraction for the drug monitoring of pediatric patients.
Topics: Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Hydro | 2005 |
On-line cation-exchange preconcentration and capillary electrophoresis coupled by tee joint interface.
Topics: Ammonium Chloride; Buffers; Cations; Chromatography, Ion Exchange; Electrophoresis, Capillary; Hydro | 2005 |
Analysis of small molecules by ultra thin-layer chromatography-atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry.
Topics: Atmospheric Pressure; Chromatography, Thin Layer; Metoprolol; Midazolam; Models, Molecular; Molecula | 2005 |
Safety and accuracy of multidetector row computed tomography for early assessment of residual stenosis of the infarct-related artery and the number of diseased vessels after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Artifacts; Calcinosis; Comorbidity; Coronary Angiography; Coronar | 2005 |
Validated kinetic spectrophotometric method for the determination of metoprolol tartrate in pharmaceutical formulations.
Topics: Adrenergic beta-Antagonists; Kinetics; Metoprolol; Reference Standards; Reproducibility of Results; | 2005 |
High-performance liquid chromatography method development and validation for simultaneous determination of five model compounds, antipyrine, metoprolol, ketoprofen, furosemide and phenol red, as a tool for the standardization of rat in situ intestinal per
Topics: Animals; Antipyrine; Chromatography, High Pressure Liquid; Drug Stability; Furosemide; Intestinal Ab | 2006 |
Capillary electrochromatography with a neutral monolithic column for classification of analytes and determination of basic drugs in human serum.
Topics: Atenolol; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Electrophoresis, Cap | 2005 |
Gas chromatographic-mass spectrometric differentiation of atenolol, metoprolol, propranolol, and an interfering metabolite product of metoprolol.
Topics: Adrenergic beta-Antagonists; Atenolol; Gas Chromatography-Mass Spectrometry; Humans; Metoprolol; Pro | 2005 |
[Value of metoprolol injection at dobutamine-atropine stress echocardiography for detection of coronary artery disease].
Topics: Aged; Coronary Disease; Echocardiography, Stress; Female; Humans; Male; Metoprolol; Middle Aged; Pre | 2005 |
Enhanced sensitivity of dobutamine stress echocardiography by observing wall motion abnormalities during the recovery phase after acute beta-blocker administration.
Topics: Adrenergic beta-Antagonists; Coronary Angiography; Coronary Disease; Dobutamine; Echocardiography, S | 2006 |
Determination of atenolol and metoprolol by capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(ii) electrochemiluminescence detection.
Topics: Adrenergic beta-Antagonists; Atenolol; Buffers; Calibration; Electrochemistry; Electrophoresis, Capi | 2007 |
Mimicry of phase I drug metabolism--novel methods for metabolite characterization and synthesis.
Topics: Biomimetics; Clinical Trials, Phase I as Topic; Cytochrome P-450 Enzyme System; Drug Evaluation, Pre | 2007 |
Simultaneous determination of beta-blockers in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Acebutolol; Adrenergic beta-Antagonists; Chromatography, Liquid; Humans; Labetalol; Linear Models; M | 2008 |
Which subgroup of patients with dilated cardiomyopathy would benefit from long-term beta-blocker therapy? A histologic viewpoint.
Topics: Adrenergic beta-Antagonists; Biopsy; Cardiac Catheterization; Cardiomyopathy, Dilated; Echocardiogra | 1993 |
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Me | 1997 |
Efficient high-performance liquid chromatographic assay for the simultaneous determination of metoprolol and two main metabolites in human urine by solid-phase extraction and fluorescence detection.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calibration; Chromatography, High Pressure Liquid | 1997 |
Determination of clenbuterol residues in bovine hair by using diphasic dialysis and gas chromatography-mass spectrometry.
Topics: Animals; Cattle; Clenbuterol; Dialysis; Gas Chromatography-Mass Spectrometry; Hair; Metoprolol; Refe | 1999 |
Chiral purity test of metoprolol enantiomer after derivatization with (-)-menthyl chloroformate by reversed-phase high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Formates; Metoprolol; Reproducibility of Results; Sensitivity | 1999 |
Determination of metoprolol enantiomers in human urine by coupled achiral-chiral chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Metoprolol; Reproducibility of Results; Sensitivity an | 2000 |
Enantioselective analysis of metoprolol in plasma using high-performance liquid chromatographic direct and indirect separations: applications in pharmacokinetics.
Topics: Adrenergic beta-Antagonists; Chromatography, High Pressure Liquid; Humans; Kinetics; Metoprolol; Rep | 2000 |
Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds.
Topics: Anions; Benzoates; Bupivacaine; Cations; Chromatography; Disopyramide; Electrophoresis, Capillary; H | 2000 |
Enantiomeric separation of metoprolol and alpha-hydroxymetoprolol by liquid chromatography and fluorescence detection using a chiral stationary phase.
Topics: Adrenergic beta-Antagonists; Biological Availability; Calibration; Chromatography, High Pressure Liq | 2001 |
Relationship between evaluation by quantitative fatty acid myocardial scintigraphy and response to beta-blockade therapy in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Fatty Acids; Female; Heart; Humans; Iodine Rad | 2001 |
Dobutamine stress echocardiography for the detection of myocardial viability in patients with left ventricular dysfunction taking beta blockers: accuracy and optimal dose.
Topics: Adrenergic beta-Antagonists; Atenolol; Cardiotonic Agents; Chronic Disease; Coronary Artery Bypass; | 2002 |