Page last updated: 2024-08-07 17:00:32

Adenylate cyclase type 5

An adenylate cyclase type 5 that is encoded in the genome of rat. [OMA:Q04400, PRO:DNx]

Synonyms

EC 4.6.1.1;
ATP pyrophosphate-lyase 5;
Adenylate cyclase type V;
Adenylyl cyclase 5

Research

Bioassay Publications (10)

TimeframeStudies on this Protein(%)All Drugs %
pre-19904 (40.00)18.7374
1990's5 (50.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Compounds (19)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
cgs 12066Rattus norvegicus (Norway rat)IC500.046811
chlorpromazineRattus norvegicus (Norway rat)IC501.300011
chlorpromazineRattus norvegicus (Norway rat)Ki0.118011
haloperidolRattus norvegicus (Norway rat)IC501.425022
quipazineRattus norvegicus (Norway rat)IC501.445411
2-chloroadenosineRattus norvegicus (Norway rat)Ki0.087012
2-fluoroadenosineRattus norvegicus (Norway rat)Ki0.099012
phenylisopropyladenosineRattus norvegicus (Norway rat)Ki0.008712
n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosineRattus norvegicus (Norway rat)Ki0.001812
2-chloro-n(6)cyclopentyladenosineRattus norvegicus (Norway rat)Ki0.038012
adenosine-5'-(n-ethylcarboxamide)Rattus norvegicus (Norway rat)Ki0.035012
n(6)-cyclopentyladenosineRattus norvegicus (Norway rat)Ki0.072012
2-chloro-n(6)-(3-iodobenzyl)adenosine-5'-n-methyluronamideRattus norvegicus (Norway rat)Ki0.001412
n-(1-methyl-2-phenylethyl)adenosine, (s)-isomerRattus norvegicus (Norway rat)Ki0.068012
s 21007Rattus norvegicus (Norway rat)IC500.398111
clozapineRattus norvegicus (Norway rat)IC500.140011

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
sk&f-38393Rattus norvegicus (Norway rat)EC500.071011
dihydrexidineRattus norvegicus (Norway rat)EC500.268625

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
1,3-dipropyl-8-cyclopentylxanthineRattus norvegicus (Norway rat)Kb0.000511
sethoxydimRattus norvegicus (Norway rat)IC1001,000.000011