s 1033 profile

ID Source	ID
PubMed CID	644241
CHEMBL ID	255863
CHEBI ID	52172
SCHEMBL ID	7901
MeSH ID	M0241686

Synonym
AC-647
nsc 747599
4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-{(4-(pyridin-3-yl)pyrimidin-2-yl)amino}benzamide
hsdb 7842
f41401512x ,
nilotinib [usan:inn:ban]
ec 700-544-5
unii-f41401512x
benzamide, 4-methyl-n-((3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-
n-(3-(3-(1h-imidazolyl)propoxy)phenyl)-4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzamide
HY-10159
c28h22f3n7o
AB01273978-01
nilotinib ,
tasigna
benzamide, 4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-
amn 107
amn-107
4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-[5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide
amn107
641571-10-0
benzamide, 4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]- (9ci)
4-methyl-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-n-[5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide
benzamide, 4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
CHEBI:52172 ,
4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
nilotinibum
CHEMBL255863 ,
NCGC00183285-03
DB04868
4-methyl-n-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
nilotinib (usan/inn)
D08953
EC-000.2344
AKOS005063561
FT-0654026
nsc-747599
nsc747599
n-8207
bdbm50237710
4-methyl-n-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
4-methyl-n-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[5-(3-pyridyl)pyrimidin-2-yl]amino]benzamide
A834657
4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-n-(5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide
NCGC00183285-01
NCGC00183285-04
4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide
BCP9000989
HMS3244B13
4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
HMS3244A13
HMS3244A14
BCPP000149
smr002544680
MLS003915611
nilotinib [usan]
nilotinib [usp-rs]
benzamide, 4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-
nilotinib [ema epar]
nilotinib [who-dd]
4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
nilotinib [mart.]
nilotinib [vandf]
nilotinib [inn]
nilotinib [hsdb]
nilotinib [mi]
3GP0
CS-0102
S1033
gtpl5697
4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
MLS006010160
AM20090651
4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide
SCHEMBL7901
AB01273978-02
DTXSID5042663 ,
4-methyl-n-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino] benzamide
Q-101348
nilotinib(amn-107)
4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
nilotinib & its intermediates
AB01273978_03
mfcd09833716
nilotinib (amn-107) ,
sr-01000931150
SR-01000931150-2
HMS3654M07
NCGC00183285-09
4-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)-phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
SW218083-2
nilotinib,amn107,tasigna;4-methyl-n-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
Q412327
nilotinib free base
641571-10-0 (free base)
1353151-22-0
AS-16214
BCP01367
BRD-K81528515-001-04-7
SB17315
HMS3295A23
HMS3748E11
CCG-264784
NCGC00183285-15
nsc-800804
nsc800804
SY024415
nilotinib- bio-x
BN164654
4-methyl-n-[3-(4-methyl-1-imidazolyl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]benzamide
dtxcid3022663
nilotinib (mart.)
nilotinib (usp-rs)
amn 107 base form
l01xe08
Z1741976994
EN300-7381984

Excerpt	Reference	Relevance
" Although these agents are normally safe and effective, they can cause side effects that lead to intolerance and necessitate switching to an alternative treatment."	( Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia. Deininger, M; Hochhaus, A; Jabbour, E, 2011)	0.37
" Nilotinib is generally well tolerated, with mild and manageable side effects, and is associated with some adverse events that require management to insure patient adherence to therapy and optimal treatment outcomes."	( Physician's guide to the clinical management of adverse events on nilotinib therapy for the treatment of CML. Baccarani, M; Castagnetti, F; Gugliotta, G; Palandri, F; Rosti, G, 2012)	0.38
" Detailed information on the occurrence and management of defined cardiac adverse events was extracted."	( Clinical cardiac safety profile of nilotinib. Dörken, B; Fateh-Moghadam, S; Giles, FJ; Grille, P; Haverkamp, W; Kim, TD; Köhncke, C; le Coutre, P; Levitin, M; Schwarz, M, 2012)	0.38
" During a median follow-up of 44 months (range, 2-73), seven patients (9%), all of whom had received prior imatinib therapy, developed 11 clinical cardiac adverse events requiring treatment."	( Clinical cardiac safety profile of nilotinib. Dörken, B; Fateh-Moghadam, S; Giles, FJ; Grille, P; Haverkamp, W; Kim, TD; Köhncke, C; le Coutre, P; Levitin, M; Schwarz, M, 2012)	0.38
"Whereas new electrocardiographic abnormalities were recorded in 20% of all patients and some of them developed severe or even life-threatening coronary artery disease, QT prolongation, changes in left ventricular ejection fraction, and clinical cardiac adverse events were uncommon in patients treated with nilotinib."	( Clinical cardiac safety profile of nilotinib. Dörken, B; Fateh-Moghadam, S; Giles, FJ; Grille, P; Haverkamp, W; Kim, TD; Köhncke, C; le Coutre, P; Levitin, M; Schwarz, M, 2012)	0.38
" Common adverse events included rash, nasopharyngitis, leukopenia, neutropenia, thrombocytopenia, nausea, headache and vomiting."	( Efficacy and safety of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL: a 36-month analysis of a phase I and II study. Amagasaki, T; Kawaguchi, T; Kobayashi, Y; Maeda, Y; Matsuda, A; Miyamura, K; Miyazaki, Y; Nagai, T; Nakaseko, C; Naoe, T; Ohyashiki, K; Okada, M; Okamoto, S; Oritani, K; Tanaka, H; Tojo, A; Usui, N; Usuki, K; Wanajo, A, 2012)	0.38
" This review discusses the potential impact of treatment-, patient-, and disease-related characteristics on the emergence of adverse events during TKI therapy, with a focus on the underlying mechanisms believed to be responsible for a number of important adverse events associated with these agents and what implications they may have for treatment choice, particularly in the setting of first-line treatment."	( Treatment-, patient-, and disease-related factors and the emergence of adverse events with tyrosine kinase inhibitors for the treatment of chronic myeloid leukemia. Irvine, E; Williams, C, 2013)	0.39
" Beside 28, UGT1A16 (*6) is another important variant allele in Japanese patients because it is associated with adverse events of irinotecan, metabolized by UGT1A1."	( Association between severe toxicity of nilotinib and UGT1A1 polymorphisms in Japanese patients with chronic myelogenous leukemia. Ando, Y; Inada-Inoue, M; Minami, Y; Mitsuma, A; Morita, S; Naoe, T; Oguri, T; Shibata, T; Shimokata, T; Sugishita, M, 2014)	0.4
" The 3 drugs clinically associated with severe cardiac adverse events (crizotinib, sunitinib, nilotinib) all proved to be cardiotoxic in our in vitro tests while the relatively cardiac-safe drug erlotinib showed only minor changes in cardiac cell health."	( Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes. Bacus, S; Brown, AM; Doherty, KR; Kramer, JW; Moran, DM; Shell, SA; Talbert, DR; Trusk, PB; Wappel, RL, 2013)	0.39
" After a 19-month median follow up, the safety profile of nilotinib 400 mg twice daily in patients switching from imatinib (n=35) was consistent with previous reports, and few new adverse events occurred in patients escalating from nilotinib 300 mg twice daily (n=19)."	( Safety and efficacy of switching to nilotinib 400 mg twice daily for patients with chronic myeloid leukemia in chronic phase with suboptimal response or failure on front-line imatinib or nilotinib 300 mg twice daily. Cervantes, F; Fan, X; Guilhot, F; Hochhaus, A; Hughes, TP; Kantarjian, HM; Kemp, C; Larson, RA; le Coutre, PD; Lobo, C; Menssen, HD; Niederwieser, D; Ossenkoppele, G; Rosti, G; Saglio, G; Shibayama, H, 2014)	0.4
" In particular, muco-cutaneous side effects represent the most frequent non-hematological adverse events."	( Tyrosine kinase inhibitors: muco-cutaneous side effects at the microscope. Brazzelli, V; Croci, G; Grasso, V; Vassallo, C, 2014)	0.4
"Chronic myeloid leukemia (CML) treatment relies on tyrosine kinase inhibitors (TKIs), but their use can be associated with low-grade adverse events (AEs)."	( Impact of low-grade adverse events on health-related quality of life in adult patients receiving imatinib or nilotinib for newly diagnosed Philadelphia chromosome positive chronic myelogenous leukemia in chronic phase. Chen, L; Guérin, A; Hiscock, R; Ionescu-Ittu, R; Keir, C; Marynchenko, M; Nitulescu, R; Wu, EQ, 2014)	0.4
"Although there is a considerable amount of data in the literature on safe discontinuation of first-generation tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia, little is known about discontinuation of second-generation tyrosine kinase inhibitor therapy."	( Safe discontinuation of nilotinib in a patient with chronic myeloid leukemia: a case report. Caocci, G; Greco, M; La Nasa, G, 2014)	0.4
"Our present case suggests that nilotinib withdrawal is safe for patients with chronic myeloid leukemia who achieve a stable undetectable molecular response."	( Safe discontinuation of nilotinib in a patient with chronic myeloid leukemia: a case report. Caocci, G; Greco, M; La Nasa, G, 2014)	0.4
"Rare but serious cardiovascular and pulmonary adverse events (AEs) have been reported in patients with chronic myeloid leukemia treated with BCR-ABL inhibitors."	( Cardiovascular and pulmonary adverse events in patients treated with BCR-ABL inhibitors: Data from the FDA Adverse Event Reporting System. Cortes, J; Malhotra, R; Mauro, M; Saglio, G; Steegmann, JL; Ukropec, JA; Wallis, NT, 2015)	0.42
"Vascular adverse events have been reported with nilotinib, a tyrosine kinase inhibitor prescribed for chronic myeloid leukaemia."	( Are nilotinib-associated vascular adverse events an under-estimated problem? Ajmia, F; Baldin, B; Drici, MD; Legros, L; Re, D; Rocher, F; Spreux, A; Stève-Dumont, M; Thyss, A, 2015)	0.42
" Although all TKIs are associated with nonhematologic adverse events (AEs), experience with imatinib suggested that toxicities are typically manageable and apparent early during drug development."	( Tyrosine Kinase Inhibitor-Associated Cardiovascular Toxicity in Chronic Myeloid Leukemia. Deininger, M; Moslehi, JJ, 2015)	0.42
"The purpose of this study was to determine the frequency of major cytogenetic response (MCyR) and adverse events with nilotinib in adults with imatinib-resistant Philadelphia chromosome-positive chronic myeloid leukemia (CML)."	( Response and Adverse Effects of Nilotinib in Imatinib-resistant Chronic Myeloid Leukemia Patients: Data From a Developing Country. Hussain, S; Usman Shaikh, M, 2015)	0.42
" The frequency of adverse effects was assessed at 6 months, and the patient overall survival was calculated after 3 years."	( Response and Adverse Effects of Nilotinib in Imatinib-resistant Chronic Myeloid Leukemia Patients: Data From a Developing Country. Hussain, S; Usman Shaikh, M, 2015)	0.42
" The most frequent nonhematologic adverse events were myalgia and headache."	( Response and Adverse Effects of Nilotinib in Imatinib-resistant Chronic Myeloid Leukemia Patients: Data From a Developing Country. Hussain, S; Usman Shaikh, M, 2015)	0.42
"The nilotinib response rates were higher in chronic phase patients, and the most common adverse events were thrombocytopenia, myalgia, and headache."	( Response and Adverse Effects of Nilotinib in Imatinib-resistant Chronic Myeloid Leukemia Patients: Data From a Developing Country. Hussain, S; Usman Shaikh, M, 2015)	0.42
" At the highest dose, we observed a slight increase in the proportion of tumor cells, likely reflecting the toxic effect of the drug on both tumor and non-tumor cells."	( A novel genetic- and cell-based tool for assessing the efficacy and toxicity of anticancer drugs in vitro. Alster, I; Hanken, H; Jiang, W; Kluwe, L, 2016)	0.43
" The promising results suggest that additional efforts are merited, for further development since such a tool will likely have high application potential (1) in drug discovery where it enables simultaneously assessing therapeutic effect on target cells and toxic effect on non-target cells, and (2) in personalized adjuvant chemotherapy where multiple drugs can be tested in primary cultures derived from surgically removed tumor."	( A novel genetic- and cell-based tool for assessing the efficacy and toxicity of anticancer drugs in vitro. Alster, I; Hanken, H; Jiang, W; Kluwe, L, 2016)	0.43
"We analyzed the adverse event rates, response rates, and survival rates of 215 patients with CML-CP with or without renal and/or liver dysfunction who had been treated with front-line nilotinib (n = 108) or dasatinib (n = 107)."	( Clinical Safety and Efficacy of Nilotinib or Dasatinib in Patients With Newly Diagnosed Chronic-Phase Chronic Myelogenous Leukemia and Pre-Existing Liver and/or Renal Dysfunction. Borthakur, G; Cortes, J; Daver, N; Ferrajoli, A; Jabbour, E; Jain, P; Kadia, T; Kantarjian, H; Lahoti, A; O'Brien, S; Pemmaraju, N; Pierce, S; Sasaki, K, 2016)	0.43
"Many patients with chronic myeloid leukemia in chronic phase experience chronic treatment-related adverse events (AEs) during imatinib therapy."	( Evaluating the Impact of a Switch to Nilotinib on Imatinib-Related Chronic Low-Grade Adverse Events in Patients With CML-CP: The ENRICH Study. Akard, LP; Busque, L; Cortes, JE; Keir, C; Lin, FP; Lipton, JH; Mauro, MJ; Miller, CB; Pinilla-Ibarz, J; Warsi, G, 2016)	0.43
"In the phase II ENRICH (Exploring Nilotinib to Reduce Imatinib Related Chronic Adverse Events) study (N = 52), the effect of switching patients with imatinib-related chronic low-grade nonhematologic AEs from imatinib to nilotinib was evaluated."	( Evaluating the Impact of a Switch to Nilotinib on Imatinib-Related Chronic Low-Grade Adverse Events in Patients With CML-CP: The ENRICH Study. Akard, LP; Busque, L; Cortes, JE; Keir, C; Lin, FP; Lipton, JH; Mauro, MJ; Miller, CB; Pinilla-Ibarz, J; Warsi, G, 2016)	0.43
"BCR-ABL1 tyrosine kinase inhibitors (TKIs) are established treatments for chronic myelogenous leukemia (CML); however, they are associated with infrequent, but clinically serious adverse events (AEs)."	( Healthcare and economic burden of adverse events among patients with chronic myelogenous leukemia treated with BCR-ABL1 tyrosine kinase inhibitors. Bilmes, R; Lin, J; Lingohr-Smith, M; Makenbaeva, D, 2017)	0.46
"We analyzed adverse events (AEs) in 201 chronic phase CML patients treated with nilotinib (n = 120) or dasatinib (n = 81) as first- or second-line therapy."	( Analysis of adverse events associated with dasatinib and nilotinib treatments in chronic-phase chronic myeloid leukemia patients outside clinical trials. Bang, SM; Kim, I; Koh, Y; Lee, JO; Lee, JY; Park, S; Shin, DY; Suh, KJ; Yoon, SS, 2017)	0.46
"Cardiotoxicity is a predominant side-effect of nilotinib during chronic myeloid leukemia treatment."	( Caspase-Independent Pathway is Related to Nilotinib Cytotoxicity in Cultured Cardiomyocytes. Chen, Y; Li, G; Meng, Z; Wei, H; Xu, Y; Yang, Q; Zhang, C, 2017)	0.46
"Spondylarthritis (SpA) is an inflammatory rheumatic disease associated with increased incidence of major adverse cardiovascular events (MACEs)."	( The use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis: does targeting inflammatory pathways with a treatment lead to vascular toxicity? Jaquinandi, V; Mahe, G; Omarjee, L, 2017)	0.46
"Cardiotoxicity is a critical side-effect of nilotinib during treatment for cancer, such as chronic myeloid leukemia, while the potential signaling mechanisms remain unclear."	( Blockage of endoplasmic reticulum stress attenuates nilotinib-induced cardiotoxicity by inhibition of the Akt-GSK3β-Nox4 signaling. Chen, Y; Meng, Z; Wen, L; Yang, Q, 2018)	0.48
" Adverse events were consistent with those reported in other nilotinib studies."	( Efficacy and safety of switching to nilotinib in patients with CML-CP in major molecular response to imatinib: results of a multicenter phase II trial (NILSw trial). Akashi, K; Hino, M; Hirase, C; Ishikawa, J; Kamimura, T; Kanakura, Y; Kawaguchi, T; Kuroda, J; Matsumura, I; Matsuoka, KI; Miyamoto, T; Nakamae, H; Shibayama, H; Shimose, T, 2018)	0.48
" However, clinical studies have highlighted increasing numbers of adverse events (AE) with TKIs."	( Efficacy and safety of nilotinib therapy in patients with newly diagnosed chronic myeloid leukemia in the chronic phase. Asou, N; Fujioka, I; Fujita, H; Hatta, Y; Iriyama, N; Ishikawa, M; Kawaguchi, T; Kimura, Y; Kizaki, M; Komatsu, N; Nakazato, T; Sato, E; Sugimoto, K; Takaku, T; Tokuhira, M, 2018)	0.48
"Some patients receiving a tyrosine kinase inhibitor (TKI) for the first-line treatment of chronic phase chronic myeloid leukemia (CML-CP) experience intolerable adverse events."	( Efficacy and safety of nilotinib 300 mg twice daily in patients with chronic myeloid leukemia in chronic phase who are intolerant to prior tyrosine kinase inhibitors: Results from the Phase IIIb ENESTswift study. Anderson, L; Branford, S; D'Rozario, J; Gervasio, O; Hiwase, D; Hughes, T; Irving, I; Levetan, C; Powell, A; Roberts, W; Solterbeck, A; Tan, P; Taper, J; Traficante, R; Wright, M; Yeung, DT, 2018)	0.48
" Of the non-hematological adverse events associated with intolerance to prior imatinib or dasatinib, 74% resolved within 12 weeks of switching to nilotinib 300 mg bid."	( Efficacy and safety of nilotinib 300 mg twice daily in patients with chronic myeloid leukemia in chronic phase who are intolerant to prior tyrosine kinase inhibitors: Results from the Phase IIIb ENESTswift study. Anderson, L; Branford, S; D'Rozario, J; Gervasio, O; Hiwase, D; Hughes, T; Irving, I; Levetan, C; Powell, A; Roberts, W; Solterbeck, A; Tan, P; Taper, J; Traficante, R; Wright, M; Yeung, DT, 2018)	0.48
"Vascular adverse events (VAEs) in chronic myeloid leukemia (CML) patients treated with nilotinib (NIL) has become a; however, studies on strategies to prevent VAEs remain limited."	( [Clinical characteristics of vascular adverse events and significance of peripheral artery disease as a risk factor in chronic myeloid leukemia patients treated with nilotinib]. Hiroshima, Y; Ichikawa, N; Kaiume, H; Kawaguchi, H; Kirihara, T; Kobayashi, H; Sato, K; Shishido, T; Sumi, M; Takeda, W; Ueki, T; Uematsu, N; Ueno, M; Urasawa, N, )	0.13
"This multicenter cooperative study aimed to analyze the adverse events (AEs) associated with tyrosine kinase inhibitors (TKIs) used as initial treatment for chronic-phase chronic myeloid leukemia (CML-CP) and their impact on outcome."	( Severe adverse events by tyrosine kinase inhibitors decrease survival rates in patients with newly diagnosed chronic-phase chronic myeloid leukemia. Fukuhara, T; Haseyama, Y; Hirayama, Y; Ikeda, H; Imamura, M; Ishihara, T; Ito, S; Kakinoki, Y; Kobayashi, H; Kobayashi, R; Kohda, K; Kondo, T; Kuroda, H; Kurosawa, M; Matsukawa, T; Mori, A; Nishio, M; Ota, S; Sakai, H; Sarashina, T; Sato, K; Shindo, M; Takahashi, T; Yamamoto, M; Yamamoto, S; Yoshida, M, 2018)	0.48
" On the brink of commercialization of generic imatinib, this study aims to evaluate the therapeutic pattern of CP-CML and the occurrence of adverse events (AEs) over a decade of local real clinical practice."	( Pattern of Use and Long-Term Safety of Tyrosine Kinase Inhibitors: A Decade of Real-World Management of Chronic Myeloid Leukemia. Bettiol, A; Chinellato, A; Crescioli, G; Gherlinzoni, F; Giusti, P; Lombardi, N; Marconi, E; Vannacci, A; Walley, T, 2018)	0.48
" The NMAs were built for six outcomes at 12 months: complete cytogenetic response (CCyR), major cytogenetic response (MCyR), deep molecular response, major molecular response (MMR), complete haematologic response and incidence of serious adverse events."	( Comparative efficacy and safety of tyrosine kinase inhibitors for chronic myeloid leukaemia: A systematic review and network meta-analysis. Aguiar, KS; Fachi, MM; Fernandez-Llimos, F; Figueiredo, BC; Lenzi, L; Leonart, LP; Pontarolo, R; Tonin, FS, 2018)	0.48
" However, adverse effects with respect to vascular disease have been reported following administration of this class of medications."	( Tyrosine kinase inhibitor toxicity manifesting as comorbid Moyamoya syndrome and obstructive coronary artery disease: A case report and review of the literature. Patterson, B; Ragosta, M; Zhuo, DX, 2019)	0.51
"Cardiovascular or arteriothrombotic adverse events (CV- or AT-AEs) are reported in chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs)."	( Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs. Ahaneku, H; Boddu, PC; Borthakur, G; Cortes, JE; Estrov, Z; Garcia-Manero, G; Jabbour, E; Jain, P; Kadia, TM; Kantarjian, H; Nogueras-González, GM; O'Brien, S; Ravandi, F; Sam, P; Sasaki, K; Verstovsek, S, 2019)	0.51
"There is little information about cardiovascular adverse event (CV-AE) incidence in chronic myeloid leukemia (CML) patients treated with bosutinib in the real-life practice."	( Incidence and evaluation of predisposition to cardiovascular toxicity in chronic myeloid leukemia patients treated with bosutinib in the real-life practice. Abruzzese, E; Annunziata, M; Baratè, C; Binotto, G; Bonifacio, M; Breccia, M; Caocci, G; Cattaneo, D; De Gregorio, F; Elena, C; Foà, R; Fozza, C; Galimberti, S; Iurlo, A; La Nasa, G; Luciano, L; Martino, B; Molica, M; Mulas, O; Orlandi, EM; Russo Rossi, A; Sgherza, N; Trawinska, MM, 2019)	0.51
" Grade 3/4 non-hematologic adverse events occurred in 11 patients (26."	( Clinical efficacy and safety of first-line nilotinib therapy and evaluation of the clinical utility of the FRET-based drug sensitivity test. Ando, S; Fujioka, M; Fujisawa, S; Haseyama, Y; Iwasaki, H; Kakinoki, Y; Kondo, T; Kurosawa, M; Miyagishima, T; Mori, A; Ohba, Y; Ota, S; Sato, K; Shindo, M; Teshima, T; Tsuda, M; Yamamoto, S, 2019)	0.51
" Pleural effusion is a frequent side effect in patients during dasatinib treatment."	( Lupus-like symptoms with anti-RNP/Sm and anti-nuclear antibodies positivity: An extremely rare adverse event of dasatinib. Bakanay, SM; Dilek, I; Kucuksahin, O; Maral, S, 2020)	0.56
"It was hypothesized that nilotinib is safe and can be detected in the cerebrospinal fluid, where it alters exploratory biomarkers via inhibition of Abelson tyrosine kinase and potentially improves clinical outcomes."	( Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease: A Phase 2 Randomized Clinical Trial. Ahn, J; Anjum, M; Arellano, J; Hebron, ML; Howard, HH; Kurd-Misto, T; Lawler, A; Liu, X; Matar, S; Moussa, C; Mulki, S; Mundel, EE; Pagan, FL; Shi, W; Starr, NJ; Torres-Yaghi, Y; Wilmarth, B; Yusuf, N, 2020)	0.56
" Doses of 150 or 300 mg of nilotinib were reasonably safe, although more serious adverse events were detected in the nilotinib (150 mg: 6 [24%]; 300 mg: 12 [48%]) vs placebo (4 [16%]) groups."	( Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease: A Phase 2 Randomized Clinical Trial. Ahn, J; Anjum, M; Arellano, J; Hebron, ML; Howard, HH; Kurd-Misto, T; Lawler, A; Liu, X; Matar, S; Moussa, C; Mulki, S; Mundel, EE; Pagan, FL; Shi, W; Starr, NJ; Torres-Yaghi, Y; Wilmarth, B; Yusuf, N, 2020)	0.56
"In this study, nilotinib appeared to be reasonably safe and detectable in the cerebrospinal fluid."	( Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease: A Phase 2 Randomized Clinical Trial. Ahn, J; Anjum, M; Arellano, J; Hebron, ML; Howard, HH; Kurd-Misto, T; Lawler, A; Liu, X; Matar, S; Moussa, C; Mulki, S; Mundel, EE; Pagan, FL; Shi, W; Starr, NJ; Torres-Yaghi, Y; Wilmarth, B; Yusuf, N, 2020)	0.56
" Adverse cardiovascular events were recorded in both groups."	( Cardiovascular Toxicity in Cancer Patients Treated with Tyrosine Kinase Inhibitors: A Real-World Single-Center Experience. Accurso, V; Badalamenti, G; Bronte, E; Di Lisi, D; Macaione, F; Novo, G; Novo, S; Rinaldi, G; Russo, A; Siragusa, S, 2020)	0.56
"Our study confirms that imatinib is a relatively safe drug, while it reveals that the latest-generation TKIs may cause a burden of cardiovascular complications."	( Cardiovascular Toxicity in Cancer Patients Treated with Tyrosine Kinase Inhibitors: A Real-World Single-Center Experience. Accurso, V; Badalamenti, G; Bronte, E; Di Lisi, D; Macaione, F; Novo, G; Novo, S; Rinaldi, G; Russo, A; Siragusa, S, 2020)	0.56
" Nilotinib was well-tolerated, although more adverse events, particularly mood swings, were noted with the 300 mg dose."	( Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease. Ahn, J; Anjum, M; Berkowitz, F; Esposito, G; Ferrante, D; Hebron, ML; Jiang, X; Lawler, A; Liu, X; Matar, S; Moussa, C; Mulki, S; Mundel, EE; Pagan, F; Shi, W; Starr, JN; Torres-Yaghi, Y; Turner, RS; Yusuf, N, 2020)	0.56
"Nilotinib is safe and achieves pharmacologically relevant cerebrospinal fluid concentrations."	( Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease. Ahn, J; Anjum, M; Berkowitz, F; Esposito, G; Ferrante, D; Hebron, ML; Jiang, X; Lawler, A; Liu, X; Matar, S; Moussa, C; Mulki, S; Mundel, EE; Pagan, F; Shi, W; Starr, JN; Torres-Yaghi, Y; Turner, RS; Yusuf, N, 2020)	0.56
"Nilotinib was safe and tolerated, and no adverse effects seemed to be related to the drug, and no differences in adverse events were observed between groups."	( Long-Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease. Ahn, J; Ferrante, D; Hebron, ML; Matar, S; Moussa, C; Mulki, S; Pagan, FL; Torres-Yaghi, Y; Wilmarth, B, 2021)	0.62
"This study provides evidence that nilotinib is safe and tolerated in Parkinson's disease."	( Long-Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease. Ahn, J; Ferrante, D; Hebron, ML; Matar, S; Moussa, C; Mulki, S; Pagan, FL; Torres-Yaghi, Y; Wilmarth, B, 2021)	0.62
" The most common all-cause adverse events were increased blood bilirubin (53."	( A phase 2 study of nilotinib in pediatric patients with CML: long-term update on growth retardation and safety. Aimone, P; Allepuz, A; Bautista, F; Ducassou, S; Dufour, C; Goto, H; Guinipero, T; Hijiya, N; Kang, HJ; Karakas, Z; Maschan, A; Millot, F; Patterson, B; Rizzari, C; Samis, J; Shimada, H; Sosothikul, D; Titorenko, K; Yoo, KH; Zwaan, CM, 2021)	0.62
" However, some patients may require dose reductions to manage the occurrences of adverse events (AEs)."	( Efficacy and safety following bosutinib dose reduction in patients with Philadelphia chromosome‒positive leukemias. An, F; Brümmendorf, TH; Cortes, JE; Crescenzo, RJ; Ferdinand, R; Gambacorti-Passerini, C; Kim, DW; Kota, V; Leip, E; Lipton, JH, 2021)	0.62

Excerpt	Reference	Relevance
"This study assessed the pharmacokinet-ics of single and multiple oral doses of nilotinib in Chinese patients with CML and compared the pharmacokinetic profiles of nilotinib between the Chinese patients and a subgroup of white patients with CML."	( Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: a single- and multiple-dose, open-label pharmacokinetic study in Chinese patients. Hu, P; Meng, F; Shen, Z; Wang, J; Wang, Y; Wei, Y; Yin, O; Zhou, L, 2009)	0.35
" Serum nilotinib concentrations were determined using a validated liquid chromatography-tandem mass spectrometry assay, and pharmacokinetic parameters of nilotinib were calculated using a noncompartmental method."	( Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: a single- and multiple-dose, open-label pharmacokinetic study in Chinese patients. Hu, P; Meng, F; Shen, Z; Wang, J; Wang, Y; Wei, Y; Yin, O; Zhou, L, 2009)	0.35
" Two patients withdrew consent and discontinued after administration of the first dose; thus, 21 patients were included in the pharmacokinetic analysis."	( Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: a single- and multiple-dose, open-label pharmacokinetic study in Chinese patients. Hu, P; Meng, F; Shen, Z; Wang, J; Wang, Y; Wei, Y; Yin, O; Zhou, L, 2009)	0.35
"In this pharmacokinetic study in Chinese patients with CML resistant to or intolerant of imatinib, nilotinib 400 mg BID was rapidly absorbed after a single dose and multiple doses."	( Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: a single- and multiple-dose, open-label pharmacokinetic study in Chinese patients. Hu, P; Meng, F; Shen, Z; Wang, J; Wang, Y; Wei, Y; Yin, O; Zhou, L, 2009)	0.35
" Post marketing study commitments have been made upon (accelerated) approval such as additional pharmacokinetic studies in patients with renal- or hepatic impairment, in children, additional interactions studies and studies on the relative or absolute bioavailability."	( Clinical pharmacokinetics of tyrosine kinase inhibitors. Gelderblom, H; Guchelaar, HJ; van Erp, NP, 2009)	0.35
" Exploratory pharmacodynamic assessment showed a general trend of greater reduction in white blood cell (WBC) levels with increase in nilotinib concentrations."	( Clinical pharmacokinetics of the BCR-ABL tyrosine kinase inhibitor nilotinib. Galitz, L; Giles, F; Grouss, K; Kantarjian, H; Ottmann, OG; Schran, H; Sethuraman, V; Smith, T; Tanaka, C; Wang, X; Yin, OQ, 2010)	0.36
" Concurrent intake of grapefruit juice increased the nilotinib peak concentration (C(max)) by 60% and the area under the serum concentration-time curve (AUC(0-infinity)) by 29% but did not affect the time to reach C(max) or the elimination half-life of nilotinib."	( Effect of grapefruit juice on the pharmacokinetics of nilotinib in healthy participants. Gallagher, N; Harrell, R; Li, A; Schran, H; Yin, OQ; Zhou, W, 2010)	0.36
" The pharmacokinetic parameters analyzed were C(max), T(max), AUC(0-last), AUC(0-infinity), t(1/2), CL/F, and Vz/F."	( Effects of hepatic impairment on the pharmacokinetics of nilotinib: an open-label, single-dose, parallel-group study. Fisher, D; Gallagher, N; Heuman, D; Lin, TH; Schran, H; Sethuraman, V; Tanaka, C; Yin, OQ; Zhou, W, 2009)	0.35
" Prothrombin time (PT) and international normalized ratio (INR) values were determined as pharmacodynamic measures of warfarin activity."	( Effects of nilotinib on single-dose warfarin pharmacokinetics and pharmacodynamics: a randomized, single-blind, two-period crossover study in healthy subjects. Fischer, D; Gallagher, N; Golor, G; Leroy, E; Schran, H; Yin, OQ; Zhao, L; Zhou, W, 2011)	0.37
" Pharmacokinetic parameters of S- and R-warfarin were similar between the two treatments (warfarin + nilotinib vs warfarin alone) in both the EM and the IM groups."	( Effects of nilotinib on single-dose warfarin pharmacokinetics and pharmacodynamics: a randomized, single-blind, two-period crossover study in healthy subjects. Fischer, D; Gallagher, N; Golor, G; Leroy, E; Schran, H; Yin, OQ; Zhao, L; Zhou, W, 2011)	0.37
" These studies show that the maximum plasma concentration of nilotinib is reached 3 to 4 hours after oral administration, with an elimination half-life of 17 hours through metabolism via oxidation and hydroxylation."	( Pharmacokinetics and pharmacodynamics of nilotinib in gastrointestinal stromal tumors. Molimard, M; Trent, J, 2011)	0.37
" Serum concentration data (sparse and full pharmacokinetic profiles) were obtained from 542 patients over 12 months."	( Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase. Clark, RE; Demirhan, E; Gallagher, NJ; Hochhaus, A; Hughes, TP; Kantarjian, HM; Larson, RA; le Coutre, PD; Nakamae, H; Saglio, G; Yin, OQ, 2012)	0.38
"Concentration data from 493 patients with CML in chronic phase (CML-CP), accelerated phase, or blast crisis were used to perform a population pharmacokinetic analysis using nonlinear mixed-effect modeling."	( Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia. Baccarani, M; Giles, FJ; Kantarjian, HM; le Coutre, PD; Ottmann, OG; Sallas, WM; Woodman, RC; Yin, OQ, 2013)	0.39
" Patients with a lower Cmin had significantly longer time to complete cytogenetic response (P = 0."	( Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia. Baccarani, M; Giles, FJ; Kantarjian, HM; le Coutre, PD; Ottmann, OG; Sallas, WM; Woodman, RC; Yin, OQ, 2013)	0.39
"When tolerability allows, adherence to the nilotinib dose (400 mg twice daily) in order to maintain sufficient Cmin is important in maximizing the efficacy of nilotinib in patients with imatinib-resistant or -intolerant CML."	( Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia. Baccarani, M; Giles, FJ; Kantarjian, HM; le Coutre, PD; Ottmann, OG; Sallas, WM; Woodman, RC; Yin, OQ, 2013)	0.39
" The human intravenous pharmacokinetic profile was projected by the Wajima 'C(ss)-MRT' method."	( Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability. He, H; Heimbach, T; Lin, TH; Xia, B, 2012)	0.38
" The results showed that pretreatment of 40mg/kg nilotinib increased the AUC0-t and Cmax of DOX and DOXol."	( Evaluation of the pharmacokinetics and cardiotoxicity of doxorubicin in rat receiving nilotinib. Guo, C; Han, YL; Li, X; Li, Y; Wan, LL; Yang, QJ; Yu, Q; Zhou, ZY, 2013)	0.39
" Calcium supplementation did not significantly affect nilotinib pharmacokinetic parameters including area under the plasma concentration versus time curve (18."	( Calcium carbonate does not affect nilotinib pharmacokinetics in healthy volunteers. Appleman, LR; Beumer, JH; Christner, SM; Egorin, MJ; Johnson, M; Lin, Y; Miller, BM; Mowrey, E; Stoller, R; Tawbi, HA; Tran, AL, 2013)	0.39
" In this paper, the pharmacokinetic characteristics (absorption, distribution, metabolism and excretion) and drug-drug interactions of the approved TKIs are reviewed."	( [Clinical pharmacokinetics of small molecule tyrosine kinase inhibitors]. Ding, JF; Zhong, DF, 2013)	0.39
" The analytical method was applied to support a pharmacokinetic study of simultaneous estimation of ruxolitinib and nilotinib in Wistar rat."	( Simultaneous quantification of ruxolitinib and nilotinib in rat plasma by LC-MS/MS: application to a pharmacokinetic study. Chennupati, S; Golla, M; Nalla, S; Rangasamy, M; Thappali, S; Vakkalanka, S; Veeraraghavan, S; Viswanadha, S, 2014)	0.4
"The objectives of this study were to determine (1) the accuracy with which individual patient level exposure can be determined and (2) whether a known food effect can be identified in a trial simulation of a typical population pharmacokinetic trial."	( Clinical trial simulation to evaluate population pharmacokinetics and food effect: capturing abiraterone and nilotinib exposures. Bies, RR; Lewis, LD; Li, CH; Sherer, EA, 2015)	0.42
" This review describes the pharmacokinetic and pharmacodynamic data of nilotinib in patients with CML and in healthy volunteers."	( Clinical Pharmacokinetic and Pharmacodynamic Overview of Nilotinib, a Selective Tyrosine Kinase Inhibitor. Aghoghovbia, M; Buchbinder, A; He, H; Heimbach, T; Hourcade-Potelleret, F; Tian, X; Zhang, H, 2018)	0.48
"To enable such efficacy studies of two clinically approved TKIs, nilotinib, and imatinib, we first conducted comprehensive pharmacokinetic (PK) studies in relevant rodent and non-rodent animal models."	( Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. Ananthula, HK; Buller, RM; Damon, IK; Desai, PB; Gallardo-Romero, N; Kalman, D; Moir-Savitz, T; Olson, V; Parker, S; Patel, G; Sallans, L; Salzer, JS; Sherwin, CM; Touchette, E; Werner, MH, 2018)	0.48
" The longer nilotinib elimination half-life in prairie dogs (i."	( Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. Ananthula, HK; Buller, RM; Damon, IK; Desai, PB; Gallardo-Romero, N; Kalman, D; Moir-Savitz, T; Olson, V; Parker, S; Patel, G; Sallans, L; Salzer, JS; Sherwin, CM; Touchette, E; Werner, MH, 2018)	0.48
" Pharmacokinetic parameters were calculated with WinNonlin software."	( Pharmacokinetics, Bioequivalence, and Safety Studies of a Generic Selective Tyrosine Kinase Inhibitor Nilotinib Capsule Versus a Branded Product in Healthy Chinese Volunteers. Huang, M; Lu, D; Wang, H; Wang, M; Zhang, Q; Zhou, W; Zhu, Y, 2022)	0.72

Excerpt	Reference	Relevance
"To study the safety, tolerability, and pharmacokinetics of the selective tyrosine kinase inhibitor nilotinib as a single agent or in combination with imatinib in patients with advanced imatinib-resistant gastrointestinal stromal tumors."	( A phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors. Bailey, SM; Bertulli, R; Blay, JY; Borghaei, H; Casali, PG; Cassier, P; Cheung, W; Davey, M; Debiec-Rychter, M; Demetri, GD; Fumagalli, E; Morgan, JA; Pink, D; Ray-Coquard, I; Reichardt, A; Reichardt, P; Veronese, ML; von Mehren, M, 2009)	0.35
"Nilotinib alone or in combination with imatinib was well tolerated overall and showed clinical activity in imatinib-resistant gastrointestinal stromal tumor patients."	( A phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors. Bailey, SM; Bertulli, R; Blay, JY; Borghaei, H; Casali, PG; Cassier, P; Cheung, W; Davey, M; Debiec-Rychter, M; Demetri, GD; Fumagalli, E; Morgan, JA; Pink, D; Ray-Coquard, I; Reichardt, A; Reichardt, P; Veronese, ML; von Mehren, M, 2009)	0.35
" Therefore, they are regularly co-administered along with treatments at risk of drug-drug interactions."	( Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib. Buclin, T; Decosterd, LA; Duchosal, MA; Haouala, A; Montemurro, M; Widmer, N, 2011)	0.37
"This study was aimed to investigate the relevance of nilotinib in combination with tetrandrine (Tet) on reversing multidrug resistance and inducing apoptosis of K562/A02 cell line and its mechanism."	( [Inducing apoptosis and reversal effect of nilotinib in combination with tetrandrine on multidrug resistance of K562/A02 cell line]. Bao, W; Chen, BA; Cheng, J; Cui, TY; Ding, JH; Gao, C; Gao, F; Schmitt, A; Schmitt, M; Shan, XY; Xia, GH; Zhong, YJ, 2011)	0.37
" In addition, nilotinib combined with the MEK1/2 inhibitor selumetinib (AZD6244) at low concentrations displayed stronger efficiency toward tumor growth inhibition, compared with nilotinib alone."	( Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2. Ammoun, S; Hanemann, CO; Manley, P; Schmid, MC; Triner, J, 2011)	0.37
"This study was aimed to investigate the effect of AMN107 (nilotinib) combined with heme oxygenase-1 (HO-1) inhibitor zinc protoporphyrin IX (ZnPPIX) on chronic myeloid leukemia (CML) cells and its mechanism."	( [CML cell apoptosis induced by AMN107 combined with heme oxygenase-1 inhibitor]. Chen, C; Fang, Q; Li, Y; Ma, D; Wang, JS; Ynag, C; Yu, YY, 2012)	0.38
" NVP-BEZ235 in combination with nilotinib also inhibited tumor growth in a xenograft model and inhibited the growth of primary T315I mutant cells and ponatinib-resistant cells."	( Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with nilotinib against BCR-ABL-positive leukemia cells involves the ABL kinase domain mutation. Kimura, S; Kitahara, T; Maekawa, T; Ohyashiki, K; Okabe, S; Tanaka, Y; Tauchi, T, 2014)	0.4
" Therefore, we focused on the comparison of the efficacy between imatinib and nilotinib in combination with IL-2 in a murine B16F10 melanoma model."	( Nilotinib combined with interleukin-2 mediates antitumor and immunological effects in a B16 melanoma model. Bauer, R; Geisler, K; Jacobs, B; Kroeger, I; Mackensen, A; Meinhardt, K; Reischer, A; Ryffel, B; Ullrich, E, 2014)	0.4
" We therefore investigated the antiproliferative effects of nilotinib in combination with drugs that are usually used for conditioning: the alkylating agents mafosfamide, treosulfan, and busulfan."	( In vitro testing of drug combinations employing nilotinib and alkylating agents with regard to pretransplant conditioning treatment of advanced-phase chronic myeloid leukemia. Dreger, P; Fruehauf, S; Ho, AD; Jens Zeller, W; Luft, T; Radujkovic, A; Topaly, J, 2014)	0.4
"Treatment of imatinib-sensitive, BCR-ABL-positive K562 and LAMA84 cells with nilotinib in combination with mafosfamide, treosulfan, or busulfan resulted in synergistic (CI < 1), additive (CI ~ 1), and predominantly antagonistic (CI > 1) effects, respectively."	( In vitro testing of drug combinations employing nilotinib and alkylating agents with regard to pretransplant conditioning treatment of advanced-phase chronic myeloid leukemia. Dreger, P; Fruehauf, S; Ho, AD; Jens Zeller, W; Luft, T; Radujkovic, A; Topaly, J, 2014)	0.4
"The effects of nilotinib on ovarian cancer cell growth were studied alone and in combination with carboplatin and paclitaxel."	( Nilotinib in combination with carboplatin and paclitaxel is a candidate for ovarian cancer treatment. Alkatout, I; Jonat, W; Maass, N; Mundhenke, C; Rath, K; Schem, C; Weigel, MT; Wenners, AS, 2014)	0.4
"Nilotinib alone and in combination with carboplatin and paclitaxel significantly inhibited cell growth in PDGFR-α-positive ovarian cancer cell lines."	( Nilotinib in combination with carboplatin and paclitaxel is a candidate for ovarian cancer treatment. Alkatout, I; Jonat, W; Maass, N; Mundhenke, C; Rath, K; Schem, C; Weigel, MT; Wenners, AS, 2014)	0.4
" We examined the effects of the MDM2 inhibitor nutlin3a and its combination with the dual Bcl-2 and Bcl-xL inhibitor ABT-737, and the Bcr-Abl inhibitor nilotinib on BC CML patient samples."	( Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells. Andreeff, M; Carter, BZ; Champlin, RE; Cortes, J; Kantarjian, HM; Konopleva, M; Mak, DH; Mak, PY; McQueen, T; Ruvolo, VR; Schober, W, 2015)	0.42
" A phase I clinical trial (NCT01702064) investigated the tolerability and safety of treating chronic-phase chronic myeloid leukemia patients with ruxolitinib in combination with the BCR-ABL TKI nilotinib and explored initial efficacy evidence."	( A phase I clinical trial of ruxolitinib in combination with nilotinib in chronic myeloid leukemia patients with molecular evidence of disease. Hazlehurst, L; Hyland, K; Kayali, F; Nelson, A; Nodzon, L; Pinilla-Ibarz, J; Powers, J; Sahakian, E; Sweet, K, 2018)	0.48
"The aim of this study is to investigate the efficacy and safety of nilotinib combined with multi-agent chemotherapy in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)."	( Nilotinib combined with multi-agent chemotherapy in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia: a single-center prospective study with long-term follow-up. Gong, B; Gong, X; Li, W; Li, Y; Lin, D; Liu, B; Liu, K; Liu, Y; Mi, Y; Wang, J; Wang, Y; Wei, H; Wei, S; Zhang, G; Zhou, C, 2019)	0.51

Excerpt	Reference	Relevance
" AMN107 is a novel, orally bioavailable ATP-competitive inhibitor of Bcr-Abl."	( AMN107, a novel aminopyrimidine inhibitor of Bcr-Abl, has in vitro activity against imatinib-resistant chronic myeloid leukemia. Alland, L; Arlinghaus, RB; Beran, M; Cortes, J; Dugan, M; Giles, F; Golemovic, M; Griffin, JD; Kantarjian, H; Manley, PW; Manshouri, T; Mestan, J; Sun, T; Verstovsek, S, 2005)	0.33
"Nilotinib is an orally bioavailable derivative of imatinib with improved specificity toward the breakpoint cluster region-Abelson murine leukemia (bcr-abl) viral protooncogene."	( Nilotinib: a second-generation tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia. Deremer, DL; Natarajan, K; Ustun, C, 2008)	0.35
" Extensive SAR studies led to the discovery of potent and orally bioavailable inhibitors, some of which demonstrated in vivo efficacy."	( 9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation. Azam, M; Banda, G; Broudy, MI; Clackson, T; Daley, GQ; Dalgarno, DC; Das, S; Huang, WS; Iuliucci, J; Keats, J; Lentini, SP; Liu, S; Ning, Y; Russian, K; Sawyer, TK; Shakespeare, WC; Snodgrass, JT; Sundaramoorthi, R; Thomas, RM; Wang, F; Wang, Y; Wardwell, S; Wen, D; Xu, Q; Zhu, X, 2009)	0.35
"Nilotinib (Tasigna), an orally bioavailable second-generation BCR-ABL tyrosine kinase inhibitor, is approved for use in patients with chronic myeloid leukemia in chronic phase and accelerated phase who are resistant or intolerant to prior therapy, including imatinib."	( Effects of rifampin and ketoconazole on the pharmacokinetics of nilotinib in healthy participants. Galitz, L; Grouss, K; Harrell, R; Schran, H; Sethuraman, V; Smith, T; Tanaka, C; Yin, OQ, 2011)	0.37
" Major gastrectomy decreased the bioavailability of nilotinib and, in some patients, lowered its clinical activity."	( Nilotinib in patients with GIST who failed imatinib and sunitinib: importance of prior surgery on drug bioavailability. Beck, MY; Chang, HM; Choi, DR; Kang, YK; Kim, KP; Kim, TW; Lee, JL; Ryoo, BY; Ryu, MH; Yoo, C, 2011)	0.37
" Bioavailability of nilotinib is increased if administered with a high-fat meal or with cytochrome P450 3A4 inhibitors, but consumption of high-fat meals to allow lower doses of nilotinib is not recommended."	( Pharmacokinetics and pharmacodynamics of nilotinib in gastrointestinal stromal tumors. Molimard, M; Trent, J, 2011)	0.37
"Nilotinib, a potent orally bioavailable BCR-ABL tyrosine kinase inhibitor, is currently available as a hard gelatin capsule that must be swallowed whole."	( Effects of yogurt and applesauce on the oral bioavailability of nilotinib in healthy volunteers. Custodio, J; Filian, J; Galetic, I; Golor, G; Krishna, A; Rudoltz, M; Schran, H; Yin, OQ; Zhou, W, 2011)	0.37
"Nilotinib is a new orally bioavailable potent tyrosine kinase inhibitor that is used for the treatment of BCR-ABL-positive chronic myelogenous leukemia."	( Anti-allergic effects of nilotinib on mast cell-mediated anaphylaxis like reactions. El-Agamy, DS, 2012)	0.38
"5-4 h and the bioavailability was moderate (17-44%)."	( Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability. He, H; Heimbach, T; Lin, TH; Xia, B, 2012)	0.38
" Herein, we report GZD824 (10a) as a novel orally bioavailable inhibitor against a broad spectrum of Bcr-Abl mutants including T315I."	( Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib. Bai, Y; Ding, K; Feng, Y; Lang, X; Leng, F; Li, Y; Liu, J; Long, H; Lu, X; Luo, J; Pan, J; Pan, X; Ren, X; She, M; Tu, Z; Wang, D; Wen, D; Zhang, F; Zhang, Z; Zhuang, X, 2013)	0.39
" We have discovered a series of 3-(2-(pyrazolo[1,5-a]pyrimidin-6-yl) ethynyl)benzamides that are selective and orally bioavailable DDR1 inhibitors."	( Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors. Ding, K; Duan, L; Gao, M; Lu, X; Luo, J; Ren, X; Tu, Z; Xu, Y; Zhang, L; Zhang, Y; Zhang, Z, 2013)	0.39
" Further optimization led to low nanomolar, orally bioavailable inhibitors that were selective for DDR1 and DDR2."	( Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors. Berdini, V; Buck, IM; Carr, ME; Cleasby, A; Coyle, JE; Curry, JE; Day, JE; Day, PJ; Hearn, K; Iqbal, A; Lee, LY; Martins, V; Mortenson, PN; Munck, JM; Murray, CW; Page, LW; Patel, S; Roomans, S; Saxty, G; Smith, K; Tamanini, E, 2015)	0.42
" It also displays good pharmacokinetics properties with an oral bioavailability of 35."	( Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant. Ding, K; Lu, X; Luo, J; Pan, X; Ren, X; Wang, D; Yu, R; Zhang, Z; Zhuang, X, 2015)	0.42
" These findings provide a mechanistic foundation of formulation development of nilotinib and other protein kinase inhibitors, which are now witnessing an intense therapeutic and industrial attention due to the difficulty in formulating these compounds so that efficient oral bioavailability is reached."	( Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation. Andersson, P; Brisander, M; Colombo, S; Haglöf, J; Malmsten, M; Sjövall, P; Østergaard, J, 2015)	0.42
" A pharmacokinetic study revealed that 18a had over 4 h of half-life and 24% bioavailability in rats."	( Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le Chen, C; Hu, Z; Liang, X; Liu, J; Liu, Q; Liu, X; Lv, F; Qi, S; Qi, Z; Wang, A; Wang, B; Wang, L; Wang, W; Zhang, S; Zhao, Z; Zou, F, 2016)	0.43
" In addtion, to improve their bioavailability and reduce their metabolism, we encapsulated sorafenib and nilotinib into styrene-co-maleic acid micelles."	( A combination of sorafenib and nilotinib reduces the growth of castrate-resistant prostate cancer. Archibald, M; Greish, K; Nehoff, H; Pritchard, T; Rosengren, RJ; Taurin, S, 2016)	0.43
"Cell membrane permeability is an important determinant for oral absorption and bioavailability of a drug molecule."	( Highly predictive and interpretable models for PAMPA permeability. Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR, 2017)	0.46
" The bioavailability of nilotinib is increased by up to 82% when given with a high-fat meal compared with fasted state."	( Clinical Pharmacokinetic and Pharmacodynamic Overview of Nilotinib, a Selective Tyrosine Kinase Inhibitor. Aghoghovbia, M; Buchbinder, A; He, H; Heimbach, T; Hourcade-Potelleret, F; Tian, X; Zhang, H, 2018)	0.48
"Marked inter-species variability in PK parameters and resulting oral bioavailability was observed."	( Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. Ananthula, HK; Buller, RM; Damon, IK; Desai, PB; Gallardo-Romero, N; Kalman, D; Moir-Savitz, T; Olson, V; Parker, S; Patel, G; Sallans, L; Salzer, JS; Sherwin, CM; Touchette, E; Werner, MH, 2018)	0.48
" This study explored the utility of lipid suspensions for enhancing oral bioavailability of the rather hydrophobic drug nilotinib in vivo in rats."	( New Insights into Using Lipid Based Suspensions for 'Brick Dust' Molecules: Case Study of Nilotinib. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2019)	0.51
"Four lipid suspensions were developed containing long chain triglycerides, medium chain triglyceride, long chain monoglycerides and medium chain monoglycerides and in vivo bioavailability was compared to an aqueous suspension."	( New Insights into Using Lipid Based Suspensions for 'Brick Dust' Molecules: Case Study of Nilotinib. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2019)	0.51
"Nilotinib lipid suspensions did not show a bioavailability increase compared to an aqueous suspension."	( New Insights into Using Lipid Based Suspensions for 'Brick Dust' Molecules: Case Study of Nilotinib. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2019)	0.51
"Monoglycerides improved oral bioavailability of nilotinib in rats, relative to triglycerides."	( New Insights into Using Lipid Based Suspensions for 'Brick Dust' Molecules: Case Study of Nilotinib. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2019)	0.51
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."	( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019)	0.51
"Nilotinib has bioavailability (BA) of only about 25% or less."	( Influence of gastrointestinal activity on the absorption of nilotinib. Aoyama, T; Sasaki, M; Sugawara, M; Takekuma, Y, 2020)	0.56
" The advent of an orally bioavailable small molecule inhibitor of the PCSK9-LDLR interaction is an attractive alternative, however efforts have been tempered as the binding interface is unfavourable for binding by small organic molecules."	( A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bonnar, J; Chemello, K; Dixon, I; Evison, BJ; Kelly, GE; Kumar, S; Lambert, G; Nativel, B; Palmer, JT; Parmar, J; Rathi, AK; Suchowerska, AK; Tang, W; Teng, Y; Treutlein, H; Wang, J; Xu, Y; Zeng, J; Zhu, Q, 2020)	0.56
"Lipid-based formulations (LBF) have shown oral bioavailability enhancement of lipophilic drugs, but not necessarily in the case of hydrophobic drugs."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
"Nilotinib in vivo bioavailability in rats was determined after administering an aqueous suspension chase dosed with blank olive oil, Captex 1000, Peceol or Capmul MCM, respectively."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
" Both long chain chase dosed excipients also significantly increased the bioavailability up to 2-fold compared to the aqueous suspension."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
"Chase dosed LBF enhanced the in vivo bioavailability of nilotinib."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56

Excerpt	Relevance	Reference
" The phase I component of the trial established the dosage regimen used in the phase II part of the trial, which included several arms."	( Nilotinib. Plosker, GL; Robinson, DM, 2008)	0.35
" Monitoring the actual BCR-ABL inhibition in nilotinib treated patients using pCRKL as a surrogate is a means to establish effective dosing and to characterize resistance mechanisms against nilotinib."	( Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib. Binckebanck, A; Debatin, J; Dugan, M; Erben, P; Ernst, T; Härtel, N; Hehlmann, R; Hochhaus, A; Holm-Eriksen, S; Konig, H; La Rosée, P; Mueller, MC; Ottmann, OG; Shou, Y; Wunderle, L, 2008)	0.35
" The calculated t((1/2)) following multiple daily dosing was approximately 17 hours."	( Nilotinib: a second-generation tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia. Deremer, DL; Natarajan, K; Ustun, C, 2008)	0.35
" Recent clinical trial developments raise questions regarding the proper dosage and schedule of these newer agents as well as the timing of their use in the treatment of patients with CML."	( Efficacy of various doses and schedules of second-generation tyrosine kinase inhibitors. Bixby, DL; Talpaz, M, 2008)	0.35
" As more clinical data become available and additional novel agents are developed, specific therapy and dosing strategies for individuals with CML will depend on the status of their disease, the anticipated side effects, and concurrent drug therapy."	( Chronic myeloid leukemia therapy: focus on second-generation tyrosine kinase inhibitors. McFarland, KL; Wetzstein, GA, 2009)	0.35
" Mean AUCs from time 0 to the end of the dosing interval tau (AUC(0-tau)) were 5076."	( Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: a single- and multiple-dose, open-label pharmacokinetic study in Chinese patients. Hu, P; Meng, F; Shen, Z; Wang, J; Wang, Y; Wei, Y; Yin, O; Zhou, L, 2009)	0.35
" Discordant responses could be related to drug dosage variations and unknown BCR-ABL independent mechanisms."	( BCR-ABL mutational studies for predicting the response of patients with chronic myeloid leukaemia to second-generation tyrosine kinase inhibitors after imatinib failure. Chan, YY; Kwan, TK; Lie, AK; Liu, HS; Ma, ES; Sim, JP; Wan, TS; Yeung, YM; Yip, SF, 2009)	0.35
" In light of the potential role of NK cells in the immunesurveillance of residual leukemia and for future combinatory immunotherapeutic approaches, our data indicate that choice and dosing of the most suitable BCR/ABL-inhibitor for a given patient require careful consideration."	( The BCR/ABL-inhibitors imatinib, nilotinib and dasatinib differentially affect NK cell reactivity. Grünebach, F; Hilpert, J; Krusch, M; Placke, T; Salih, HR; Salih, J; Steinle, A, 2010)	0.36
" Imatinib is remarkably effective as treatment for CML in the chronic phase (at a dosage of 400 mg/d) and the accelerated phase (at 600 mg/d)."	( Update on practical aspects of the treatment of chronic myeloid leukemia with imatinib mesylate. Schiffer, CA; Zonder, JA, 2006)	0.33
" These results indicate that concurrent use of strong CYP3A4 inducers or inhibitors may necessitate dosage adjustments of nilotinib and should be avoided when possible."	( Effects of rifampin and ketoconazole on the pharmacokinetics of nilotinib in healthy participants. Galitz, L; Grouss, K; Harrell, R; Schran, H; Sethuraman, V; Smith, T; Tanaka, C; Yin, OQ, 2011)	0.37
" The different dosing requirements of dasatinib (once daily with or without food) and nilotinib (twice daily with fasting) may be an additional factor in selecting frontline agents."	( First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib. Liu, D; Rafiyath, S; Wei, G, 2010)	0.36
" Most patients achieved planned dosing of 400 mg twice daily and maintained the dose >12 months."	( Expanding Nilotinib Access in Clinical Trials (ENACT): an open-label, multicenter study of oral nilotinib in adult patients with imatinib-resistant or imatinib-intolerant Philadelphia chromosome-positive chronic myeloid leukemia in the chronic phase. De Souza, C; Gallagher, N; Jootar, S; le Coutre, P; Nicolini, FE; Powell, BL; Shen, ZX; Szczudlo, T; Turkina, A; Zheng, M, 2012)	0.38
" Because continuous and adequate dosing is important to achieve this outcome, it is important to understand treatment adherence as part of managing long-term CML therapy."	( Adherence to treatment with second-line therapies, dasatinib and nilotinib, in patients with chronic myeloid leukemia. Cziraky, M; Davis, C; Hamdan, M; Hirji, I; Oliveria, SA; Yood, MU, 2012)	0.38
" Moreover, daily doses calculated based on refill records may not reflect accurate dosing regimens."	( A retrospective analysis of therapy adherence in imatinib resistant or intolerant patients with chronic myeloid leukemia receiving nilotinib or dasatinib in a real-world setting. Chen, L; Griffin, JD; Guérin, A; Ponce de Leon, D; Wu, EQ, 2012)	0.38
" However, achieving maximum benefit with these drugs may require optimal dosing and adherence to therapy."	( Simultaneous measurement of imatinib, nilotinib and dasatinib in dried blood spot by ultra high performance liquid chromatography tandem mass spectrometry. Kralj, E; Kristl, A; Pajič, T; Trontelj, J, 2012)	0.38
" However, the newer targeted anticancer therapies have different pharmacokinetic (PK) and dosing characteristics compared with traditional cytotoxic drugs, making it possible to estimate the steady-state drug exposure with a single trough-level measurement."	( Evidence for therapeutic drug monitoring of targeted anticancer therapies. Balakrishnar, B; Clements, A; Gao, B; Gurney, H; Wong, M; Yeap, S, 2012)	0.38
"This study evaluated the effects of either famotidine or antacid on the pharmacokinetics of nilotinib in healthy subjects, with the specific focus to explore different dosing separation schemes leading to a minimized drug-drug interaction."	( Effects of famotidine or an antacid preparation on the pharmacokinetics of nilotinib in healthy volunteers. Bédoucha, V; Hussaini, A; McCulloch, T; Novick, S; Yin, OQ; Zheng, C; Zhou, W, 2013)	0.39
" Sorafenib dosage was reduced in a third of patients, but this did not have an impact on progression-free survival (PFS) (p=0."	( Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis. Bauer, S; Bitz, U; Blay, JY; Duffaud, F; Gelderblom, H; Joensuu, H; Montemurro, M; Pink, D; Rutkowski, P; Schütte, J; Trent, J, 2013)	0.39
" Conversely, when nilotinib was discontinued due to liver dysfunction, the dosage of injected insulin was decreased and urine C-peptide levels increased."	( Nilotinib exacerbates diabetes mellitus by decreasing secretion of endogenous insulin. Akashi, K; Chong, Y; Ito, Y; Kamimura, T; Maki, T; Miyamoto, T, 2013)	0.39
" With similar levels of efficacy, the choice of second-generation agents should be guided by the characteristics of the individual patient and the most suitable dosing regimen."	( Second-generation tyrosine kinase inhibitors in first-line treatment of chronic myeloid leukaemia (CML). Abruzzese, E; Breccia, M; Latagliata, R, 2014)	0.4
" We used Hill's equation for in vitro response of Ba/F3 cells transduced with various BCR-ABL mutants to determine IC(50) and the slope of the dose-response curve."	( Integrating in vitro sensitivity and dose-response slope is predictive of clinical response to ABL kinase inhibitors in chronic myeloid leukemia. Druker, BJ; Eide, CA; O'Hare, T; Shukron, O; Vainstein, V, 2013)	0.39
" Common concerns include how to best select therapy based upon patient-specific comorbidities, monitoring and interpretation of treatment outcomes, and optimization of dosing when side effects occur."	( BCR-ABL inhibitors: updates in the management of patients with chronic-phase chronic myeloid leukemia. Bixby, DL; Khan, AM, 2014)	0.4
" However, clinically relevant dosing of these adenosine triphosphate-mimetic agents in humans leads to inhibition of numerous tyrosine kinases beyond those touted by drug manufacturers and studied in landmark clinical trials."	( Off-Target Effects of BCR-ABL and JAK2 Inhibitors. Fancher, KM; Green, MR; Newton, MD, 2016)	0.43
" Rabbits dosed intravenously (IV) with crizotinib or nilotinib showed QTc prolongation."	( Liposomes ameliorate Crizotinib- and Nilotinib-induced inhibition of the cardiac IKr channel and QTc prolongation. Bouchard, A; Helson, L; Majeed, M; Salvail, D; Shopp, GM, 2014)	0.4
" In TKI therapy for CML patients, therapeutic drug monitoring is a new strategy for dosage optimization to obtain a faster and more effective clinical response."	( Therapeutic drug monitoring of imatinib, nilotinib, and dasatinib for patients with chronic myeloid leukemia. Miura, M, 2015)	0.42
" A 50 mg/kg/day dosage treatment could almost completely suppress tumor progression in the K562 cells inoculated xenograft mouse model."	( Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le Chen, C; Hu, Z; Liang, X; Liu, J; Liu, Q; Liu, X; Lv, F; Qi, S; Qi, Z; Wang, A; Wang, B; Wang, L; Wang, W; Zhang, S; Zhao, Z; Zou, F, 2016)	0.43
" Augmentation of LDR and Nilotinib therapy seems to be beneficial to control Ph+ leukemia resistance and the quantitative model can determine optimal dosing schedule to enhance the effectiveness of the combination therapy."	( Combination therapeutics of Nilotinib and radiation in acute lymphoblastic leukemia as an effective method against drug-resistance. Farrar, MA; Foo, J; Guido, M; Hui, SK; Kaveh, K; Leder, KZ; Penning, J; Piepenburg, J; Storme, G; Takahashi, Y, 2017)	0.46
"A total of 54 patients were divided into two groups according to the dosage of nilotinib."	( [Correlation of Serum Concentration of Nilotinib with Clinical Efficacy in Patients with Chronic Myeloid Leukemia]. Chen, XC; Gu, CH; Li, CX; Wang, P; Wang, T; Wu, DP; Yang, D; Zou, Q, 2018)	0.48
" The Cmins of nilotinib relate with the dosage and grade III-IV of adverse events."	( [Correlation of Serum Concentration of Nilotinib with Clinical Efficacy in Patients with Chronic Myeloid Leukemia]. Chen, XC; Gu, CH; Li, CX; Wang, P; Wang, T; Wu, DP; Yang, D; Zou, Q, 2018)	0.48
" PK of these agents following intravenous and oral dosing were evaluated in C57BL/6 mice, prairie dogs, guinea pigs and Cynomolgus monkeys."	( Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. Ananthula, HK; Buller, RM; Damon, IK; Desai, PB; Gallardo-Romero, N; Kalman, D; Moir-Savitz, T; Olson, V; Parker, S; Patel, G; Sallans, L; Salzer, JS; Sherwin, CM; Touchette, E; Werner, MH, 2018)	0.48
"5 h), facilitated multiple dosing PK and safety assessment."	( Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. Ananthula, HK; Buller, RM; Damon, IK; Desai, PB; Gallardo-Romero, N; Kalman, D; Moir-Savitz, T; Olson, V; Parker, S; Patel, G; Sallans, L; Salzer, JS; Sherwin, CM; Touchette, E; Werner, MH, 2018)	0.48
" With the updated dosing recommendations, select patients with chronic phase myeloid leukemia (CML) taking nilotinib for 3 years or more and whose leukemia has responded with sustained molecular remission (MR4."	( U.S. Food and Drug Administration Benefit-Risk Assessment of Nilotinib Treatment Discontinuation in Patients with Chronic Phase Chronic Myeloid Leukemia in a Sustained Molecular Remission. Bloomquist, E; Deisseroth, A; Farrell, A; McKee, AE; Pazdur, R; Pulte, ED; Tang, S; Wroblewski, T, 2019)	0.51
" Future (confirmatory) studies should further explore the usefulness of nilotinib dosing together with food, including the relationship with treatment efficacy as well as long-term effects on quality of life."	( Food-effect study of nilotinib in chronic myeloid leukaemia (NiFo study): Enabling dose reduction and relief of treatment burden. Boons, CCLM; den Hartog, YM; Hendrikse, NH; Hugtenburg, JG; Janssen, JJWM; Swart, EL; Vos, RM; Zandvliet, AS, 2020)	0.56
" This study explored the potential of lipid vehicles to improve the bioavailability of the hydrophobic drug nilotinib comparing a chase dosing approach and lipid suspensions."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
"Nilotinib in vivo bioavailability in rats was determined after administering an aqueous suspension chase dosed with blank olive oil, Captex 1000, Peceol or Capmul MCM, respectively."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
"Compared to the lipid suspensions, the chase dosed lipids showed a 2- to 7-fold higher bioavailability."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
"Chase dosed LBF enhanced the in vivo bioavailability of nilotinib."	( Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats. Griffin, BT; Holm, R; Koehl, NJ; Kuentz, M, 2020)	0.56
" After the nilotinib dosage was reduced to 400 mg, liver biopsy, also performed in 1996 + 20, revealed hypertrophy of renal small blood vessels and endothelial cells of the hepatic artery and loss of endothelial cells of the renal glomeruli, portal vein, and hepatic sinusoids."	( Pathological findings suggesting vascular endothelial damage in multiple organs in chronic myelogenous leukemia patients on long-term tyrosine kinase inhibitor therapy. Hasegawa, G; Koda, R; Morita, S; Nagano, O; Seki, Y, 2020)	0.56
" If the serum bilirubin level exceeds 3 times the upper limit of normal, the recommendation is to either adjust nilotinib dosage or temporarily discontinue the treatment."	( Nilotinib-induced liver injury: A case report. Tan, Y; Ye, Y; Zhou, X, 2020)	0.56
"Nilotinib dosage was reduced together with introduction of hydroxychloroquine with progressive improvement of alopecia."	( Lichen planopilaris-like eruption in chronic myeloid leukemia patient during treatment with nilotinib as second-line therapy. Gardellini, A; Guidotti, F; Maino, E; Steffanoni, S; Turrini, M; Zancanella, M, 2022)	0.72
" Second, the binding of asciminib decreases the binding free energies of nilotinib by ∼3 and ∼7 kcal/mol for the wildtype and T315I-mutated protein, respectively, suggesting the possibility of reducing nilotinib dosage and lowering risk of developing resistance in the treatment of CML."	( Allosteric enhancement of the BCR-Abl1 kinase inhibition activity of nilotinib by cobinding of asciminib. Amiri, W; Friedman, R; Lindahl, E; Oruganti, B; Rahimullah, R; Yang, J, 2022)	0.72

Role	Description
antineoplastic agent	A substance that inhibits or prevents the proliferation of neoplasms.
tyrosine kinase inhibitor	Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
anticoronaviral agent	Any antiviral agent which inhibits the activity of coronaviruses.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
(trifluoromethyl)benzenes	An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens.
pyrimidines	Any compound having a pyrimidine as part of its structure.
pyridines	Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives.
imidazoles	A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
secondary amino compound	A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups.
secondary carboxamide	A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathway	Proteins	Compounds
Nilotinib Inhibition of BCR-ABL	19	1

Protein Targets (511)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Fumarate hydratase	Homo sapiens (human)	Potency	11.7704	0.0030	8.7949	48.0869	AID1347053
polyprotein	Zika virus	Potency	11.7704	0.0030	8.7949	48.0869	AID1347053
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	Potency	22.3872	0.0096	10.5250	35.4813	AID1479145
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Carbonic anhydrase 12	Homo sapiens (human)	Ki	0.3020	0.0002	1.1043	9.9000	AID428457
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	IC50 (µMol)	4.7000	0.0003	2.6311	9.0000	AID1207755
Solute carrier family 22 member 3	Homo sapiens (human)	IC50 (µMol)	0.5000	0.0900	3.7277	9.5000	AID1745861
Tyrosine-protein kinase ABL1	Homo sapiens (human)	GI50	0.2454	0.0002	0.6136	9.6450	AID1286550; AID1286558; AID1286560; AID1286561; AID1286562; AID1286563; AID1386050; AID1386051; AID1386084; AID1386085; AID1386086; AID1386087; AID1386088; AID1386089; AID1386090; AID1386091
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50 (µMol)	0.4978	0.0001	0.7128	10.0000	AID1240468; AID1240469; AID1337170; AID1496117; AID1611401; AID1611402; AID1611403; AID1611405; AID1611406; AID1611407; AID1611408; AID1648793; AID1666985; AID1799594; AID1854087; AID1876065; AID1876260; AID1886530; AID1886531; AID1918398; AID463625; AID515831; AID515832; AID590028; AID722273; AID724974; AID724975; AID724976; AID724977; AID724978; AID724979; AID724980; AID724981; AID744878
Carbonic anhydrase 1	Homo sapiens (human)	Ki	0.0293	0.0000	1.3726	10.0000	AID428366
Carbonic anhydrase 2	Homo sapiens (human)	Ki	0.0041	0.0000	0.7236	9.9200	AID428367
Low-density lipoprotein receptor	Homo sapiens (human)	IC50 (µMol)	9.8000	9.8000	9.8000	9.8000	AID1666983
Fibronectin	Homo sapiens (human)	IC50 (µMol)	1.9400	0.1200	0.1200	0.1200	AID1799594
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	IC50 (µMol)	1.1000	0.0010	0.3349	8.9000	AID322453
Tyrosine-protein kinase Lck	Homo sapiens (human)	GI50	0.8700	0.0010	0.4570	0.8700	AID1286554
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50 (µMol)	0.1082	0.0002	1.3173	10.0000	AID722272
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	IC50 (µMol)	0.6770	0.0006	0.5676	5.5450	AID515833
Carbonic anhydrase 3	Homo sapiens (human)	Ki	0.4430	0.0002	2.0102	10.0000	AID428368
Tyrosine-protein kinase Lyn	Homo sapiens (human)	IC50 (µMol)	1.2810	0.0002	0.5594	5.2000	AID722269
Tyrosine-protein kinase HCK	Homo sapiens (human)	GI50	4.1000	0.0390	4.6130	9.7000	AID1286556
Cytochrome P450 3A4	Homo sapiens (human)	IC50 (µMol)	0.5800	0.0001	1.7536	10.0000	AID1648798
Macrophage colony-stimulating factor 1 receptor	Mus musculus (house mouse)	IC50 (µMol)	0.5340	0.0026	0.2356	0.5340	AID1757435
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50 (µMol)	0.0520	0.0006	0.8007	8.5000	AID1666986; AID515828; AID722267
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50 (µMol)	0.4175	0.0007	0.4708	10.0000	AID1666984; AID463624; AID515830; AID722257; AID722258; AID722259; AID722260; AID722263; AID722274
Breakpoint cluster region protein	Homo sapiens (human)	GI50	0.2454	0.0002	0.6289	9.6450	AID1286550; AID1286558; AID1286560; AID1286561; AID1286562; AID1286563; AID1386050; AID1386051; AID1386084; AID1386085; AID1386086; AID1386087; AID1386088; AID1386089; AID1386090; AID1386091
Breakpoint cluster region protein	Homo sapiens (human)	IC50 (µMol)	0.1129	0.0003	0.6200	10.0000	AID1240468; AID1240469; AID1496117; AID1611401; AID1611402; AID1611403; AID1611405; AID1611406; AID1611407; AID1611408; AID1800272; AID1854087; AID1876065; AID515831; AID515832; AID590028; AID744878
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	GI50	0.4700	0.0003	0.6476	2.1000	AID1286551
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50 (µMol)	1.9300	0.0002	0.5335	10.0000	AID1666987; AID1799594
Solute carrier family 2, facilitated glucose transporter member 4	Mus musculus (house mouse)	IC50 (µMol)	0.0420	0.0420	0.2575	0.4730	AID515832
Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)	IC50 (µMol)	398.1070	0.1200	4.0480	10.0000	AID1207379
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	IC50 (µMol)	1.0905	0.0027	1.6287	9.9000	AID1337173; AID1339539
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50 (µMol)	0.0368	0.0001	0.4912	10.0000	AID515829; AID722270
Carbonic anhydrase 4	Homo sapiens (human)	Ki	0.4460	0.0002	1.9720	9.9200	AID428369
Carbonic anhydrase 6	Homo sapiens (human)	Ki	0.4610	0.0001	1.4710	9.9200	AID428372
Ephrin type-A receptor 2	Homo sapiens (human)	IC50 (µMol)	0.0330	0.0008	0.0436	0.2626	AID1802324
Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)	Ki	5.4850	0.0000	1.2725	9.9000	AID428370
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50 (µMol)	9.5480	0.0001	0.3275	9.5480	AID722271
Carbonic anhydrase 7	Homo sapiens (human)	Ki	0.0990	0.0002	1.3737	9.9000	AID428373
Tyrosine-protein kinase Blk	Homo sapiens (human)	GI50	1.3000	0.0050	1.8017	4.1000	AID1286555
Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)	IC50 (µMol)	398.1070	0.1200	4.0480	10.0000	AID1207379
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	IC50 (µMol)	4.7000	0.0003	2.5955	9.0000	AID1207755
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	GI50	1.1000	1.1000	2.3667	3.0000	AID1286552
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	IC50 (µMol)	0.0371	0.0005	0.2657	2.8900	AID1202712; AID1337172; AID1800098; AID515827; AID732858
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50 (µMol)	21.2239	0.0009	1.9014	10.0000	AID1207473; AID1207533; AID1648799
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	IC50 (µMol)	4.7000	0.0003	2.6311	9.0000	AID1207755
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	IC50 (µMol)	1,122.1687	0.0003	2.2545	9.6000	AID1207289; AID1207567; AID1207755
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	IC50 (µMol)	3,005.9351	0.0003	3.6484	9.2000	AID1207319; AID1207349
Carbonic anhydrase 9	Homo sapiens (human)	Ki	0.0419	0.0001	0.7874	9.9000	AID428374
Discoidin domain-containing receptor 2	Homo sapiens (human)	GI50	1.4000	1.4000	4.0333	7.7000	AID1286553
Discoidin domain-containing receptor 2	Homo sapiens (human)	IC50 (µMol)	0.0289	0.0004	0.3938	9.0000	AID1141136; AID1141137; AID1202713; AID1800098; AID515826; AID722275; AID732857
Multidrug resistance-associated protein 1	Rattus norvegicus (Norway rat)	Ki	0.0467	0.0025	0.0452	0.1090	AID428367; AID428373; AID428374
Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)	IC50 (µMol)	9.8000	0.7500	5.2750	9.8000	AID1666983
Carbonic anhydrase 15	Mus musculus (house mouse)	Ki	0.0790	0.0009	1.8846	10.0000	AID428460
Carbonic anhydrase 13	Mus musculus (house mouse)	Ki	4.6650	0.0002	1.3974	9.9000	AID428458
Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)	IC50 (µMol)	3,162.2800	1.4000	5.3500	9.3000	AID1207439
Carbonic anhydrase 14	Homo sapiens (human)	Ki	0.2230	0.0002	1.5099	9.9000	AID428459
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	IC50 (µMol)	2.5000	0.0040	1.9666	10.0000	AID1873222
Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)	Ki	14.9200	0.0000	1.3412	9.9700	AID428371
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	10.0000	0.9300	2.5478	5.7000	AID625128
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	20.0000	0.0009	1.1413	3.7000	AID1424922; AID624825
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	0.2040	0.2040	0.2040	AID1425109
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	0.5110	0.5110	0.5110	AID1424936
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	0.0033	1.5175	7.6000	AID624974
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	20.0000	0.0008	1.5144	9.0000	AID1425121; AID625076
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	10.0000	0.0120	2.5734	9.2000	AID625059
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	0.4350	0.4350	0.4350	AID1424975
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	0.0005	1.0152	5.2000	AID624877
Pyridoxal kinase	Homo sapiens (human)	Kd	30.0000	0.2860	5.0765	16.4040	AID1425106
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	20.0000	0.0330	3.0646	48.8760	AID1424954; AID625065
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	10.0000	0.0077	1.4099	9.7000	AID624926
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	0.0270	1.4471	5.3000	AID624722
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	20.0000	0.0028	1.4744	8.7000	AID1424953; AID624831
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	0.0120	1.5827	6.3000	AID624836
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	10.0000	0.0190	0.9330	2.8000	AID624749
Aurora kinase A	Homo sapiens (human)	Kd	20.0000	0.0001	0.7342	9.3000	AID1424917; AID624919
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	20.0000	0.0003	0.9086	28.6510	AID1425009; AID625012
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	10.0000	0.0049	1.8360	8.1000	AID624966
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	10.0000	0.0058	1.5058	5.9000	AID624832
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	10.0000	0.0031	0.6128	4.1000	AID625022
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	15.2500	0.0000	1.0768	9.0000	AID1424995; AID624957
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	0.0260	1.3140	2.6020	AID1424896
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	10.0000	0.0001	1.4667	6.6000	AID624892
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0017	1.3432	3.5000	AID624876
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	10.0000	0.0160	0.9316	5.3000	AID624965
Death-associated protein kinase 3	Homo sapiens (human)	Kd	10.0000	0.0010	1.8241	9.9000	AID624834
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	10.0000	0.0015	1.6660	8.5000	AID624724
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	20.0000	0.0020	1.6212	11.4330	AID1425155; AID624925
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	30.0000	0.0940	1.3910	3.5070	AID1424926
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	10.0000	0.0037	0.5214	5.9000	AID625088
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0170	0.3610	0.7050	AID1425097
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	10.0000	0.0180	2.4890	6.7000	AID624751
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	10.0000	0.0000	0.8851	7.0000	AID624973
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	0.2320	0.2320	0.2320	AID1424986
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	20.0000	0.0002	2.7105	56.0660	AID1425158; AID624969
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	20.0000	0.0008	1.8410	23.2730	AID1425208; AID624916
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	20.0000	0.0057	2.0095	12.2010	AID1424997; AID624835
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	20.0000	0.0170	1.9737	29.9570	AID1425162; AID624736; AID624967
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1.3820	1.3820	1.3820	AID1425174
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	16.6667	0.0120	1.6396	7.2000	AID1425161; AID624806; AID624927
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	20.0000	0.0017	1.2483	9.9690	AID1425179; AID624775
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	0.0032	1.0024	7.5000	AID624958
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	10.0000	0.0005	1.4483	5.7000	AID624873
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	23.3333	0.0017	1.4788	7.3000	AID1424951; AID624905
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	10.0000	0.0048	2.1982	9.4000	AID624942
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	18.4000	0.0000	2.9234	57.4530	AID1425177; AID625030
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	20.0000	0.0089	2.2738	23.3410	AID1425137; AID625024
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	10.0000	0.0160	0.9920	3.6000	AID625070
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	0.2090	0.6575	1.1060	AID1425173
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	20.0000	0.1700	1.5781	8.0000	AID1425050; AID624962
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	10.0000	0.0480	2.3498	8.0000	AID624977
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	20.0000	0.0082	2.3645	62.7720	AID1425054; AID624756
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	20.0000	0.0140	1.8393	10.7330	AID1425033; AID624963
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	23.3333	0.0027	2.5694	30.3710	AID1425100; AID624811
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	10.0000	0.0071	1.2729	7.7000	AID624803
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	0.5620	0.0000	1.0411	13.4530	AID1424890; AID1525531; AID1801731; AID1801733; AID624978; AID624979; AID624980; AID624981; AID624982; AID624983; AID624984; AID624985; AID624986; AID624987; AID624988; AID624989; AID624990; AID624991; AID624992; AID722268
Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)	Kd	0.0130	0.0000	0.0315	0.2960	AID1801731; AID1801733
Epidermal growth factor receptor	Homo sapiens (human)	Kd	11.5385	0.0001	1.3514	20.8270	AID1424983; AID624996; AID624997; AID624998; AID624999; AID625000; AID625001; AID625002; AID625003; AID625004; AID625005; AID625006; AID625007
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	3.9000	0.0066	1.1467	4.4000	AID624897
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	10.0000	0.0008	1.2931	5.1000	AID624804
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	20.0000	0.0020	1.3484	9.2000	AID1425094; AID624808
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	0.4510	0.4510	0.4510	AID1425169
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	0.0013	2.7081	26.3240	AID1425130
Insulin receptor	Homo sapiens (human)	Kd	20.0000	0.0017	1.0823	7.9060	AID1425026; AID624784
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	15.0235	0.0002	1.1174	24.2210	AID1425034; AID625013
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	15.8000	0.0008	1.4238	8.4000	AID1425008; AID624727
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	0.2880	1.4952	3.0490	AID1424937
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	2.1210	2.1210	2.1210	AID1425146
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	20.0000	0.0048	1.0986	7.4000	AID1425003; AID624852
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	0.0450	0.0006	0.6993	8.1000	AID624995
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	15.5500	0.0003	1.3708	17.1520	AID1425212; AID625018
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	0.8535	0.0006	1.0485	5.7000	AID1425037; AID624862
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	10.3940	0.0007	0.8642	27.5420	AID1425154; AID625121; AID625122; AID625123; AID625124
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	20.0000	0.0010	1.9211	19.2170	AID1425022; AID624800
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	0.0080	0.0080	0.0080	AID1425176
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.2020	0.2020	0.2020	AID1424969
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	15.0000	0.0002	1.6297	8.5000	AID1425076; AID624794; AID624795; AID624796
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	15.1950	0.0003	2.0343	15.9930	AID1425017; AID624857
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	10.0000	0.0005	1.1741	5.8000	AID624899
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	10.0297	0.0001	1.0050	11.1070	AID1425104; AID624875; AID722262
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	0.3200	0.0005	1.0721	7.8000	AID625011
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0039	2.1874	9.4000	AID624746
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	10.0000	0.0250	1.4739	5.8000	AID624747
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	0.0470	9.6832	33.6550	AID1424915
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	0.2089	0.0002	0.8159	9.8000	AID624786; AID624787; AID624788; AID624789; AID624790; AID624791; AID624792; AID624793; AID722264
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	3.5690	3.5690	3.5690	AID1425145
Breakpoint cluster region protein	Homo sapiens (human)	Kd	0.6510	0.0030	1.2196	17.3640	AID1424919
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	20.0000	0.0010	1.1393	19.3160	AID1425111; AID624878
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	20.0000	0.0003	1.5581	6.2000	AID1425004; AID625132
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	0.0640	0.2750	0.4860	AID1425202
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	16.6667	0.0033	1.6050	8.6000	AID1424946; AID624780; AID624781
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	0.0060	0.2505	0.4950	AID1425170
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	15.9500	0.0002	1.5077	9.6000	AID1425175; AID625016
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	0.0520	1.7535	3.4550	AID1425128
Insulin receptor-related protein	Homo sapiens (human)	Kd	10.0000	0.0062	1.3814	4.6000	AID625075
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	10.7567	0.0002	1.6258	26.0180	AID1424924; AID624946; AID624947
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	5.1655	0.0001	2.0569	9.5000	AID1425110; AID624797
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	1.4840	0.0040	6.7556	88.9030	AID1425093
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	0.1270	0.0004	0.7090	8.8000	AID625034; AID722261
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	20.0000	0.0014	1.3604	8.8000	AID1425002; AID625010
Protein kinase C alpha type	Homo sapiens (human)	Kd	30.0000	0.0003	1.7922	21.3520	AID1425129
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	20.0000	0.0039	2.9479	23.2450	AID1425123; AID624881
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	10.0000	0.0007	0.9585	9.9000	AID624853
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	30.0000	0.0020	1.6906	12.0220	AID1424996
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	10.0000	0.1200	2.3238	7.4000	AID624896
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	20.0000	0.0010	2.5309	28.8720	AID1424968; AID624849
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	0.0330	0.0330	0.0330	AID1425150
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	10.0000	0.0280	1.3461	2.6000	AID625025
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	10.0000	0.0084	0.8679	2.1000	AID624708
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	15.2950	0.0041	1.8000	9.8000	AID1424987; AID625008
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	10.0000	0.0310	1.1579	5.5000	AID625131
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	0.0008	2.2545	9.2000	AID624851
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	5.4810	5.4810	5.4810	AID1425098
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	10.0000	0.1100	2.6773	7.2000	AID625130
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	10.0000	0.0230	1.2652	6.9000	AID624782; AID624783
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	0.0020	8.5577	49.2780	AID1425125
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	20.0000	0.0130	0.7408	4.1000	AID1425124; AID624882
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	2.9190	0.2430	6.4343	67.9140	AID1425001; AID1801713
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	20.0000	0.0013	1.1805	4.8000	AID1425164; AID624906
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	16.6667	0.0016	1.2166	7.8000	AID1425030; AID624858; AID624859
Protein kinase C eta type	Homo sapiens (human)	Kd	10.0000	0.0004	0.2881	1.8000	AID625049
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	20.0000	0.0070	1.5179	10.4870	AID1424944; AID624844
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	0.1700	5.5791	22.4940	AID1424908
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	4.1030	4.1030	4.1030	AID1424977
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	0.0100	2.0789	8.9000	AID624838
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	20.0000	0.4300	5.2743	9.8000	AID1425061; AID624885
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	20.0000	0.0030	3.9689	58.2400	AID1425069; AID624863
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	0.0120	1.0875	2.1630	AID1424970
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	20.0000	0.0001	2.7441	7.3000	AID1425056; AID624713
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	0.4723	0.0009	1.0752	8.1980	AID1424988; AID1802323; AID624951
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	0.1100	0.0001	2.1521	8.6000	AID625009
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	0.0370	0.0002	1.2875	7.7000	AID625120
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	15.3200	0.0004	3.1536	53.1980	AID1424992; AID625105
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	10.0000	0.0010	2.0631	7.5000	AID624743
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	16.6667	0.0009	1.5575	8.7000	AID1425207; AID624912; AID624913
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	0.0030	0.0045	0.0060	AID1424959
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	0.0030	0.0030	0.0030	AID1425107
Wee1-like protein kinase	Homo sapiens (human)	Kd	20.0000	0.0014	3.5389	65.1580	AID1425210; AID624914
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	0.1190	0.1190	0.1190	AID1425018
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	10.0000	0.0001	1.2891	6.3000	AID624840
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	1.1000	3.0556	5.4000	AID624886
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	0.9620	0.9620	0.9620	AID1424980
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	0.0006	1.0621	4.4000	AID1424910; AID624994
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	0.0021	1.6196	8.7000	AID1424911; AID624839
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	10.0000	0.0120	1.6852	7.3000	AID624739
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	10.0000	0.0065	1.6269	8.5000	AID624910
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	0.6290	0.6290	0.6290	AID1425072
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	10.0000	0.0090	1.8725	8.4000	AID625141
Myosin-10	Homo sapiens (human)	Kd	30.0000	0.2290	0.4935	0.7580	AID1425079
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	1.0000	0.0003	1.0645	5.7000	AID625017
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	10.0000	0.0015	0.9450	7.2000	AID624854
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	10.0000	0.0002	0.8063	5.7000	AID624860
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	20.0000	0.0039	1.6429	9.6000	AID1425039; AID625137
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	15.5556	0.0002	0.9559	9.9000	AID1425006; AID624934; AID624935; AID624936; AID624937; AID624938; AID624939; AID624940; AID722266
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	20.0000	0.0600	1.5010	7.0000	AID1424921; AID624945
Activin receptor type-1B	Homo sapiens (human)	Kd	20.0000	0.0040	1.5110	15.2580	AID1424901; AID624943
TGF-beta receptor type-1	Homo sapiens (human)	Kd	20.0000	0.0050	2.2785	9.6000	AID1425196; AID624961
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	0.0029	1.9936	9.5000	AID624778
TGF-beta receptor type-2	Homo sapiens (human)	Kd	20.0000	0.0800	1.8351	6.9000	AID1425197; AID624909
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	16.2000	0.0010	3.4578	39.5530	AID1424960; AID624948
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	0.0400	0.0400	0.0400	AID1425010
Protein kinase C iota type	Homo sapiens (human)	Kd	20.0000	0.0260	9.3316	51.0180	AID1425133; AID624883
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	2.6070	2.6070	2.6070	AID1425168
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	0.0006	0.8462	7.4000	AID625036; AID625037; AID625038; AID625039; AID625040; AID625041; AID625042; AID625043; AID625044; AID625045
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	0.0017	0.8316	6.7000	AID625046
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	0.0001	0.5993	9.2000	AID624972
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	10.0000	0.2600	3.0700	7.7000	AID624864
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	20.0000	0.0010	1.0095	8.7000	AID1425193; AID624908
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	10.0000	0.0006	1.9196	6.0000	AID624911
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	0.1585	0.0002	1.1249	14.9240	AID1424891; AID624993
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	0.3230	0.0003	1.2424	10.8370	AID1425007; AID624855
G protein-coupled receptor kinase 6	Homo sapiens (human)	Kd	30.0000	1.1890	1.4020	1.6150	AID1425012
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	0.0160	1.6844	4.2000	AID624744
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	20.0000	0.0070	2.0052	9.2260	AID1425188; AID624907
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	0.0050	0.0050	0.0050	AID1425141
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	15.2250	0.0110	2.0965	26.0590	AID1425063; AID624889
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	17.9000	0.0020	1.4596	8.1000	AID1425064; AID624717
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	10.0000	0.0038	1.6264	9.9000	AID624902
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	20.0000	0.0050	2.0462	6.6000	AID1425040; AID624894
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	0.2080	3.6125	7.0170	AID1425113
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	20.0000	0.0010	2.5756	19.3520	AID1424961; AID624846
Casein kinase I isoform delta	Homo sapiens (human)	Kd	20.0000	0.0150	2.2270	18.3960	AID1424962; AID624716
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	0.0026	1.4602	8.4000	AID624879
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	20.0000	0.0003	2.0274	14.7420	AID1425065; AID624703
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	10.0000	0.0014	1.2908	8.0000	AID624829
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.4640	0.4640	0.4640	AID1425206
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	0.0120	0.3320	0.6520	AID1424932
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	20.0000	0.0130	1.4086	12.4090	AID1424963; AID624847
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1.6890	1.6890	1.6890	AID1424894
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	2.1000	0.0020	1.8791	29.8810	AID1436039; AID624764
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	10.0000	0.0070	1.1384	6.5000	AID624932
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	10.0000	0.0100	2.4499	9.0000	AID624931
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	20.0000	0.0060	2.4754	22.5430	AID1425013; AID625114
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	20.0000	0.0070	1.0057	6.1680	AID1425014; AID624856
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	20.0000	0.0025	1.6783	7.7000	AID1424949; AID624845
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	20.0000	0.0010	1.6166	9.9010	AID1424950; AID624830
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	4.4930	4.4930	4.4930	AID1425149
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	0.5000	0.0002	0.8228	7.9000	AID624841
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	20.0000	0.0061	1.5252	8.5000	AID1425027; AID624837
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	20.0000	0.0170	2.8896	37.6050	AID1425160; AID624960
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	0.0014	1.5489	7.4000	AID624842
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	10.0000	0.0072	1.3066	5.8000	AID624976
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	20.0000	0.1100	1.5649	6.5000	AID1425086; AID624869
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	20.0000	0.1700	5.9368	38.0880	AID1425087; AID624870
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	0.4600	1.5320	2.7000	AID624904
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	10.0000	0.0002	1.0688	8.7000	AID624785
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	20.0000	0.0034	2.3943	6.5000	AID1425043; AID624895
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	10.0000	0.0001	0.5711	5.0000	AID624975
Death-associated protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0014	1.2542	4.7000	AID624971
LIM domain kinase 1	Homo sapiens (human)	Kd	20.0000	0.0260	1.7840	21.0890	AID1425035; AID624861
LIM domain kinase 2	Homo sapiens (human)	Kd	20.0000	0.0570	4.9717	52.0560	AID1425036; AID625021
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	10.0000	0.0001	2.2138	9.9000	AID624766
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	16.0000	0.0010	1.6354	5.9000	AID1425057; AID624891
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	3.3160	3.3160	3.3160	AID1425211
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	30.0000	0.0060	1.4681	10.2120	AID1425126
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	10.0000	0.0120	0.7798	5.0000	AID625047
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	15.5000	0.0069	2.1713	6.4100	AID1424993; AID624955
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	15.9500	0.0002	1.2100	5.9000	AID1424990; AID624737
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	15.3650	0.0003	2.1678	26.3990	AID1424994; AID624956
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	1.3000	0.0004	1.7216	7.3000	AID624954
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	20.1100	0.0012	3.1525	43.9420	AID1424989; AID624952
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1.0360	1.0360	1.0360	AID1424909
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	0.0130	1.8368	3.4930	AID1424907
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	10.0000	0.0037	2.5139	9.8000	AID625084
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	10.0000	0.0022	1.1530	3.2000	AID624733
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	10.0000	0.0130	1.5506	9.8000	AID624763
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1.3480	1.3480	1.3480	AID1425148
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	0.8000	3.2333	5.6000	AID624760
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	0.0360	2.7735	5.5110	AID1424899
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	0.0040	0.0040	0.0040	AID1424898
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	0.7900	0.0003	0.8538	3.3000	AID624759
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	0.7590	0.7590	0.7590	AID1425153
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	10.0000	0.0006	1.7635	7.5000	AID624848
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	10.0000	0.0170	0.8655	7.8000	AID624915
SRSF protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0150	0.2803	1.1000	AID624768
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	20.0000	0.0460	1.4506	6.6000	AID1424965; AID624833
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	10.0000	0.0035	2.2093	9.9000	AID624706
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	10.0000	0.0032	1.2724	5.5000	AID624753
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	20.0000	0.0080	3.0602	63.6140	AID1424945; AID624828
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	0.0130	0.7332	2.1000	AID624941
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	0.0320	1.2007	3.3560	AID1424948
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	20.0000	0.0430	1.3757	8.3000	AID1424947; AID624970
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	20.0000	0.0011	1.5855	10.0000	AID1424941; AID625033
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	20.0000	0.0010	0.8233	5.6000	AID1424942; AID624776
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	0.9830	0.9830	0.9830	AID1425108
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	0.0002	0.5849	8.1000	AID625014
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	20.0000	0.0002	1.1386	8.7730	AID1425038; AID624893
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	1.0000	0.0031	1.3464	6.7000	AID624799
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	10.0000	0.0038	2.1074	6.9000	AID624867
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	0.1480	1.2270	2.5970	AID1425203
Protein kinase C theta type	Homo sapiens (human)	Kd	20.0000	0.0007	1.6140	7.2000	AID1425134; AID625051
Activin receptor type-1	Homo sapiens (human)	Kd	20.0000	0.0040	1.4853	16.1210	AID1424900; AID624819
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	20.0000	0.0030	2.0718	8.4000	AID1425078; AID624868
Focal adhesion kinase 1	Homo sapiens (human)	Kd	20.0000	0.0005	1.2255	13.0390	AID1425142; AID624729
Protein kinase C delta type	Homo sapiens (human)	Kd	20.0000	0.0002	1.1261	9.2060	AID1425131; AID625048
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	20.0000	0.0006	1.5299	10.1530	AID1424925; AID624779
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	10.0000	0.0020	2.2066	9.3000	AID625057
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	20.0000	0.0140	1.4941	8.4000	AID1424943; AID624874
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	20.0000	0.0020	1.7138	9.6000	AID1425201; AID624807
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	0.0581	0.0002	1.6314	71.4840	AID1424972; AID624850
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	10.0000	0.0130	0.8600	5.6000	AID625020
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	0.0035	2.0528	7.0000	AID624950
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	23.3333	0.0031	1.4681	14.0430	AID1425052; AID624959
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	10.0000	0.0220	1.0554	6.3000	AID624762
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	20.0000	0.0003	1.7055	6.8000	AID1425075; AID624767
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	20.0000	0.0002	1.7120	25.9020	AID1425185; AID625055
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	20.0000	0.0037	1.8913	15.3890	AID1425122; AID624773
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	10.0000	0.0006	1.6206	4.4000	AID624871
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	15.0950	0.0002	2.6590	65.6770	AID1425042; AID624721
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	20.0000	0.0420	2.0073	9.9000	AID1425062; AID624888
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	20.0000	0.0031	2.3045	6.0000	AID1425099; AID624872
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	20.0000	0.0002	1.8602	17.5260	AID1425182; AID625054
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	20.0000	0.0970	2.5995	12.4730	AID1425044; AID625026
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0031	0.8310	3.6000	AID625053
Integrin-linked protein kinase	Homo sapiens (human)	Kd	0.0200	0.0200	0.4603	1.3290	AID1425024
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	20.0000	0.0003	1.7555	13.4620	AID1425157; AID625015
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	20.0000	0.0018	1.0064	11.2690	AID1425200; AID624930
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	10.0000	0.0084	1.1899	7.6000	AID624750
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0200	1.1487	5.4000	AID624924
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	10.0000	0.0013	1.7221	6.8000	AID624827
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	20.0000	0.0005	1.0209	7.8000	AID1424929; AID624731
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	20.0000	0.0003	1.5044	20.3010	AID1424928; AID624770
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	20.0000	0.0001	2.1016	40.2910	AID1424981; AID624712
Activin receptor type-2B	Homo sapiens (human)	Kd	20.0000	0.0076	2.7328	9.9000	AID1424902; AID624820
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	20.0000	0.0190	2.5917	14.3770	AID1424923; AID624826
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	20.0000	0.0043	1.7430	9.0000	AID1425144; AID625029
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	20.0000	0.0016	0.7072	3.8000	AID1425138; AID625052
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	20.0000	0.0009	1.2571	4.5180	AID1424940; AID624761
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	10.0000	0.0270	2.2925	7.0000	AID624922
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	20.0000	0.0051	1.1093	8.3000	AID1425023; AID625074
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	20.0000	0.0011	1.9450	30.4140	AID1425143; AID624732
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	20.0000	0.0049	2.2835	29.9330	AID1425074; AID625087
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	0.3650	0.3650	0.3650	AID1425172
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	0.0030	0.0030	0.0030	AID1424952
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	10.0000	0.0140	1.4116	8.4000	AID624884
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	10.0000	0.0560	1.5651	9.4000	AID625067
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	10.0000	0.0009	1.2548	7.0000	AID624815
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	10.0000	0.0089	2.0421	9.6000	AID624805; AID625127
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	20.0000	0.0025	1.4445	6.5000	AID1424991; AID624953
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	0.4320	0.4320	0.4320	AID1424978
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	16.6667	0.0280	2.5286	22.7260	AID1425159; AID624900; AID624901
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	20.0000	0.0330	1.7568	5.6000	AID1425194; AID625056
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	20.0000	0.0030	1.2088	7.9000	AID1425081; AID624709
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	1.8895	0.0001	0.4610	3.7430	AID1425058; AID624890
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	20.0000	0.0030	0.9949	5.9000	AID1425178; AID624798
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	10.0000	0.0010	0.6864	2.2000	AID624898
NT-3 growth factor receptor	Homo sapiens (human)	Kd	0.6000	0.0034	1.2020	8.6000	AID624765
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	23.3333	0.0013	3.1729	49.8130	AID1425117; AID624745
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	20.0000	0.0018	1.7527	9.9000	AID1425118; AID625050
Mitogen-activated protein kinase 14	Homo sapiens (human)	EC50 (µMol)	4.6000	0.0052	1.5141	5.9000	AID1865191
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	0.6157	0.0000	0.5036	8.5000	AID1286625; AID1425059; AID624714
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	10.0000	0.0300	1.9215	5.4600	AID624843
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	20.0000	0.0110	1.5639	17.9840	AID1425045; AID624866
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	0.4900	0.0038	0.7875	7.2000	AID625032
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	0.1700	1.9167	5.5000	AID624887
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	10.0000	0.0004	1.5589	7.1000	AID625035
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	0.0934	0.0030	1.9888	42.2800	AID1141134; AID1141140; AID1424973; AID624777; AID722265
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	20.0000	0.0012	1.3707	13.7110	AID1424889; AID625089
Myosin light chain kinase 3	Homo sapiens (human)	Kd	20.0000	0.0020	1.6184	10.4240	AID1425082; AID624738
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	10.0000	0.0032	0.9048	4.8000	AID624812
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	10.0000	0.0005	0.8420	6.4000	AID625136
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	2.5660	2.5660	2.5660	AID1425019
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	0.3600	0.0110	1.7345	7.2000	AID625097
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	4.8300	4.8300	4.8300	AID1425151
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0004	1.2042	9.7000	AID624740; AID624741
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	20.0000	0.0570	4.5547	14.0200	AID1424933; AID624920
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	20.0000	0.0370	1.9625	9.5000	AID1424935; AID625107
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	0.0780	1.6997	3.9570	AID1424892
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	10.0000	0.0130	2.4114	7.3000	AID624742
Serine/threonine-protein kinase N3	Homo sapiens (human)	Kd	30.0000	0.0990	0.7365	1.3740	AID1425119
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	20.0000	0.0012	1.3350	9.9000	AID1425209; AID624818
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	10.0000	0.0053	1.7337	6.4000	AID624758
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	10.0000	0.0025	0.9909	2.8000	AID624801
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	30.0000	0.0030	1.2292	9.3110	AID1425147
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1.9160	3.0730	4.1470	AID1424893
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	0.1160	0.7604	1.5000	AID1424998
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	20.0000	0.0001	1.8425	11.1030	AID1425068; AID625106
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	0.0060	0.0060	0.0060	AID1424979
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	17.3500	0.0004	2.1612	18.7570	AID1425189; AID625126
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	0.3160	1.7208	3.6720	AID1425186
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	0.0230	3.1137	22.7470	AID1424904
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	10.0000	0.0160	0.9012	2.6000	AID624771
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	0.0550	2.1688	8.0000	AID624734
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	10.0000	0.0005	1.3428	5.8000	AID624802
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	0.0630	1.9933	4.0000	AID625058
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	10.0000	0.0150	0.6659	3.4000	AID624809
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0550	1.6626	6.8000	AID624726
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	10.0000	0.0011	1.8547	5.9000	AID625118
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	20.0000	0.0051	1.6413	15.4350	AID1425053; AID624921
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	0.0039	1.4549	5.1000	AID624822
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	20.0000	0.0080	1.1241	3.1180	AID1425067; AID624923
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	10.0000	0.0035	1.9863	8.9000	AID624929
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	10.0000	0.1400	2.6188	8.7000	AID624728
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	10.0000	0.0008	1.0884	9.9000	AID625085
Misshapen-like kinase 1	Homo sapiens (human)	Kd	20.0000	0.0010	1.1425	8.9000	AID1425077; AID624813
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	10.0000	0.0160	1.6907	4.5000	AID624814
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	10.0000	0.0000	1.1411	5.1000	AID625143
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	10.0000	0.2500	2.2056	7.1000	AID624723
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	10.0000	0.0005	1.3339	8.1000	AID624720
Myosin-IIIa	Homo sapiens (human)	Kd	10.0000	0.0410	1.6626	6.3000	AID625104
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	10.0000	0.0320	1.6534	9.4000	AID624735
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	0.1700	1.2350	3.1000	AID624725
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	20.0000	0.0940	5.1673	65.3020	AID1424905; AID625116
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	19.4000	0.0030	2.7522	8.8000	AID1425115; AID625134
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	20.0000	0.0049	0.6880	4.5000	AID1425060; AID624715
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	20.0000	0.0160	2.7428	19.6170	AID1425089; AID624704
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	10.0000	0.0140	2.3924	8.4000	AID624702
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	10.0000	0.0020	0.9706	5.4000	AID624711
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	20.0000	0.0030	3.6719	8.7000	AID1425088; AID624754
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	10.0000	0.0009	1.2793	7.5000	AID624719
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	10.0000	0.0130	2.2043	5.5000	AID624821
Myosin-IIIb	Homo sapiens (human)	Kd	10.0000	0.0810	2.4155	7.1000	AID624817
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	0.0860	0.0860	0.0860	AID1424974
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	10.0000	0.0220	2.3693	7.6000	AID624918
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	10.0000	0.0005	1.3519	5.9000	AID624928
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	15.4450	0.0010	0.9378	5.5000	AID1425051; AID624816
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	10.0000	0.0034	1.3561	7.2000	AID625073
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	0.0270	2.3213	6.1000	AID625135
Aurora kinase B	Homo sapiens (human)	Kd	20.0000	0.0020	1.0614	22.8520	AID1424918; AID624772
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	20.0000	0.0054	1.1029	4.9000	AID1425070; AID625140
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	10.0000	0.0010	1.9148	6.8000	AID625119
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	23.3333	0.1700	2.4294	8.3000	AID1425085; AID625068
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	10.0000	0.0320	1.8886	8.6000	AID624718
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1.0670	1.0670	1.0670	AID1425102
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	20.0000	0.0000	3.2331	52.8470	AID1424931; AID625060
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	0.3110	1.9519	3.8400	AID1425204
Dual specificity testis-specific protein kinase 2	Homo sapiens (human)	Kd	30.0000	0.0020	0.0020	0.0020	AID1425195
SRSF protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0055	1.0891	5.2000	AID624903
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	20.0000	0.0440	0.9285	2.9000	AID1425116; AID624757
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	20.0000	0.0700	6.5647	50.5360	AID1425049; AID625028
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	10.0000	0.0360	1.8381	9.7000	AID624824
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	20.0000	0.0060	1.5331	9.9000	AID1425047; AID624865
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	20.0000	0.0580	1.9224	4.8360	AID1424984; AID625080
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	10.0000	0.0090	1.3195	8.4000	AID625141
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0260	1.9734	7.3000	AID624823
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	10.0000	0.0490	1.7667	9.1000	AID625111
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	10.0000	0.0015	1.9204	7.2000	AID625094
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	0.0079	0.0079	0.0079	AID625110
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0240	2.8577	6.3000	AID625142
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	10.0000	0.0018	1.3542	4.9000	AID625138
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	0.0090	4.1035	8.1980	AID1425016
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	20.0000	0.0081	2.3723	25.0190	AID1425136; AID625102
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	10.0000	0.0045	1.4011	6.5000	AID624707
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	20.0000	0.0001	0.6774	4.6000	AID1425095; AID625139
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1.2400	1.2400	1.2400	AID1425083
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	20.0000	0.0011	1.8165	41.7950	AID1425166; AID625095
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	10.0000	0.0430	1.1312	5.4000	AID624705
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	0.0000	3.8573	99.2320	AID1425171; AID625086
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	15.8500	0.0002	2.7131	14.1960	AID1425191; AID625101
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0073	1.3739	5.0000	AID625129
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	10.0000	0.0130	2.6007	9.8000	AID624710
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	10.0000	0.0040	1.7046	9.7000	AID625023
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	0.0040	2.9056	8.5000	AID624933
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	0.5730	1.7403	3.0540	AID1424971
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	18.5500	0.0020	1.4122	8.3000	AID1424958; AID625125
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0014	1.4131	5.7000	AID625108
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	0.0063	1.3385	4.4000	AID625079
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	20.0000	0.0530	2.0622	5.7000	AID1424964; AID625128
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	10.0000	0.0004	1.9194	9.7000	AID625115
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	0.0900	0.5520	1.5000	AID624752
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	10.0000	0.0010	1.6879	8.0000	AID625083
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	10.0000	0.1800	2.7651	8.3000	AID625096
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	0.0030	0.0045	0.0060	AID1425000
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0110	0.0110	0.0110	AID1425020
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	20.0000	0.0022	2.4097	56.0320	AID1424920; AID625109
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	0.0030	0.0050	0.0070	AID1425096
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	20.0000	0.0017	3.4719	34.1450	AID1425029; AID625098
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	10.0000	0.0240	2.7040	6.4000	AID625112
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	0.5315	0.0023	1.7034	13.6380	AID1425213; AID624755
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	0.0320	1.8032	5.6350	AID1424939
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	10.0000	0.0008	1.8083	8.3000	AID625063
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	3.9200	3.9200	3.9200	AID1425084
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	10.0000	0.0040	1.2615	4.9000	AID625113
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	20.0000	0.0019	0.8415	5.0000	AID1425112; AID625064
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	10.0000	0.0012	0.8801	3.3000	AID625117
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	20.0000	0.0074	1.7380	8.3000	AID1425181; AID625103
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	10.0000	0.0033	1.1828	4.4000	AID624810
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0070	0.0070	0.0070	AID1425187
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	20.0000	0.0060	1.0226	4.4000	AID1425090; AID625100
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	10.0000	0.0390	1.1982	3.5000	AID624880
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	10.0000	0.0010	1.7218	9.0000	AID624968
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	10.0000	0.1300	0.9879	3.7000	AID625071
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	0.6400	0.0011	1.0255	9.1000	AID624748
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	30.0000	0.0050	1.1581	9.1280	AID1425127
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	20.0000	0.0009	1.7674	49.6010	AID1425192; AID625072
Septin-9	Homo sapiens (human)	Kd	30.0000	0.0100	0.2430	0.6350	AID1425165
Death-associated protein kinase 2	Homo sapiens (human)	Kd	10.0000	0.0016	1.1261	9.1000	AID625077
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	16.6667	0.0040	2.4153	23.7620	AID1425163; AID625081; AID625082
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	20.0000	0.0047	1.3935	10.0000	AID1425199; AID625093
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	10.0000	0.0270	1.0513	4.0000	AID625069
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	20.0000	0.0100	2.0176	12.9420	AID1425190; AID625099
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	20.0000	0.0005	1.3507	7.7000	AID1424913; AID624944
SRSF protein kinase 3	Homo sapiens (human)	Kd	10.0000	0.0120	2.1154	9.3000	AID625078
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	10.0000	0.0007	1.4717	9.3000	AID625090
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	10.0000	0.0052	0.6617	1.3000	AID625133
Aurora kinase C	Homo sapiens (human)	Kd	10.0000	0.0013	1.0848	8.7000	AID624769
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	10.0000	0.0001	1.6996	9.6000	AID624730
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	0.0025	1.7646	6.2000	AID1424912; AID625019
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	10.0000	0.0280	1.4692	6.9000	AID625092
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	0.0190	1.5420	6.2000	AID625091
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	20.0000	0.0005	1.5086	10.3180	AID1425167; AID624774
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	20.0000	0.0024	1.3298	6.9000	AID1425046; AID625062
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	2.7460	2.7460	2.7460	AID1425198
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	10.0000	0.0280	1.8129	9.5000	AID624964
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	23.3333	0.0005	1.9494	50.2140	AID1425055; AID625061
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	1.2740	0.0110	1.4797	6.7000	AID1425156
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	15.4550	0.0340	3.6252	50.0050	AID1424934; AID625031
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	20.0000	0.0070	1.7137	25.5810	AID1425028; AID625066
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	20.0000	0.0065	0.8920	4.0840	AID1425180; AID624917
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	20.0000	0.0970	2.3978	8.7000	AID1424966; AID624949
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	20.0000	0.0390	2.3970	8.4000	AID1425048; AID625027
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (3190)

Process	via Protein(s)	Taxonomy
positive regulation of gene expression	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
cartilage condensation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
ovarian cumulus expansion	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
osteoblast differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
eye development	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
chondrocyte development	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
inflammatory response	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
central nervous system neuron differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
proteoglycan biosynthetic process	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of bone mineralization	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
BMP signaling pathway	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
retinal ganglion cell axon guidance	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of chondrocyte differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
ovulation cycle	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of osteoblast differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
retina development in camera-type eye	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
endochondral bone morphogenesis	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of cartilage development	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
cellular response to BMP stimulus	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
negative regulation of chondrocyte proliferation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
dorsal/ventral pattern formation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
protein phosphorylation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
cellular response to growth factor stimulus	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
heme biosynthetic process	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
positive regulation of lipoprotein transport	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of cell population proliferation	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of nuclear cell cycle DNA replication	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cell cycle phase transition	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cell division	Cell division cycle 7-related protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	Cell division cycle 7-related protein kinase	Homo sapiens (human)
double-strand break repair via break-induced replication	Cell division cycle 7-related protein kinase	Homo sapiens (human)
signal transduction	Cell division cycle 7-related protein kinase	Homo sapiens (human)
phosphorylation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
natural killer cell differentiation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of cytokine production	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
adaptive immune response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
mast cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
respiratory burst involved in defense response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
protein phosphorylation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
inflammatory response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
immune response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of endothelial cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of gene expression	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
T cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
natural killer cell activation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
B cell differentiation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
T cell differentiation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
neutrophil chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of neutrophil apoptotic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
natural killer cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
B cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
T cell activation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
B cell activation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
mast cell degranulation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
innate immune response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of angiogenesis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
T cell receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
B cell receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
mast cell differentiation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
neutrophil extravasation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of epithelial tube formation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
phosphatidylinositol-3-phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
positive regulation of centriole replication	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
centriole replication	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
positive regulation of centriole replication	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
trophoblast giant cell differentiation	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 25	Homo sapiens (human)
response to oxidative stress	Serine/threonine-protein kinase 25	Homo sapiens (human)
establishment or maintenance of cell polarity	Serine/threonine-protein kinase 25	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase 25	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase 25	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase 25	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase 25	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Serine/threonine-protein kinase 25	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 25	Homo sapiens (human)
positive regulation of axonogenesis	Serine/threonine-protein kinase 25	Homo sapiens (human)
Golgi localization	Serine/threonine-protein kinase 25	Homo sapiens (human)
establishment of Golgi localization	Serine/threonine-protein kinase 25	Homo sapiens (human)
Golgi reassembly	Serine/threonine-protein kinase 25	Homo sapiens (human)
translational initiation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
chromosome segregation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
response to virus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA secondary structure unwinding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of gene expression	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
Wnt signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of translation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of cell growth	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of cell growth	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of protein-containing complex assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein autophosphorylation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of type I interferon production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
DNA duplex unwinding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of interferon-alpha production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of interferon-beta production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
stress granule assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of toll-like receptor 7 signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of toll-like receptor 8 signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
intracellular signal transduction	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of translation in response to endoplasmic reticulum stress	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytosolic ribosome assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of viral genome replication	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
innate immune response	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of translation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of translational initiation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
lipid homeostasis	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cellular response to arsenic-containing substance	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cellular response to osmotic stress	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of chemokine (C-C motif) ligand 5 production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
intrinsic apoptotic signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cellular response to virus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of non-canonical NF-kappaB signal transduction	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein acetylation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein K63-linked ubiquitination	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein localization to cytoplasmic stress granule	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of gene expression	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
gamete generation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cell differentiation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
biological_process	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
cellular response to starvation	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
autophagosome organization	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
cell migration	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
phosphatidylinositol-3-phosphate biosynthetic process	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
pyridoxal 5'-phosphate salvage	Pyridoxal kinase	Homo sapiens (human)
pyridoxal metabolic process	Pyridoxal kinase	Homo sapiens (human)
pyridoxamine metabolic process	Pyridoxal kinase	Homo sapiens (human)
mitotic cell cycle	Citron Rho-interacting kinase	Homo sapiens (human)
mitotic cytokinesis	Citron Rho-interacting kinase	Homo sapiens (human)
positive regulation of cytokinesis	Citron Rho-interacting kinase	Homo sapiens (human)
negative regulation of hippo signaling	Citron Rho-interacting kinase	Homo sapiens (human)
generation of neurons	Citron Rho-interacting kinase	Homo sapiens (human)
neuron apoptotic process	Citron Rho-interacting kinase	Homo sapiens (human)
chromosome segregation	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
maturation of SSU-rRNA	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
positive regulation of interferon-beta production	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
negative regulation of MDA-5 signaling pathway	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
negative regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
innate immune response	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
positive regulation of innate immune response	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
defense response to virus	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
cellular response to dsRNA	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
cellular response to virus	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
cellular response to dsDNA	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
apoptotic process	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
response to osmotic stress	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
JNK cascade	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
response to heat	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
response to UV	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
response to wounding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
response to tumor necrosis factor	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of JUN kinase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of JNK cascade	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of telomerase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
cellular response to lipopolysaccharide	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
cellular response to interleukin-1	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
positive regulation of telomere capping	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
regulation of motor neuron apoptotic process	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
inner cell mass cell proliferation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
DNA replication	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
DNA repair	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
chromatin remodeling	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleus organization	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of double-strand break repair via homologous recombination	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of cell population proliferation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
signal transduction in response to DNA damage	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
mitotic G2/M transition checkpoint	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
positive regulation of cell cycle	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of gene expression, epigenetic	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of mitotic nuclear division	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of mitotic centrosome separation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of G0 to G1 transition	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cellular response to mechanical stimulus	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cellular response to caffeine	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
replicative senescence	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
apoptotic process involved in development	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of DNA biosynthetic process	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
inflammatory response	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
response to virus	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
peptidyl-serine phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
cortical actin cytoskeleton organization	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
toll-like receptor 3 signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
negative regulation of myosin-light-chain-phosphatase activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
TRIF-dependent toll-like receptor signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
regulation of phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
innate immune response	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
positive regulation of DNA-templated transcription	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
T cell receptor signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
stress-activated MAPK cascade	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein maturation	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
cellular response to tumor necrosis factor	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein localization to plasma membrane	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
regulation of establishment of endothelial barrier	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
negative regulation of bicellular tight junction assembly	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
regulation of toll-like receptor signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
negative regulation of cell-matrix adhesion	Peripheral plasma membrane protein CASK	Homo sapiens (human)
cell adhesion	Peripheral plasma membrane protein CASK	Homo sapiens (human)
negative regulation of keratinocyte proliferation	Peripheral plasma membrane protein CASK	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Peripheral plasma membrane protein CASK	Homo sapiens (human)
GMP metabolic process	Peripheral plasma membrane protein CASK	Homo sapiens (human)
GDP metabolic process	Peripheral plasma membrane protein CASK	Homo sapiens (human)
establishment of localization in cell	Peripheral plasma membrane protein CASK	Homo sapiens (human)
negative regulation of wound healing	Peripheral plasma membrane protein CASK	Homo sapiens (human)
calcium ion import	Peripheral plasma membrane protein CASK	Homo sapiens (human)
positive regulation of calcium ion import	Peripheral plasma membrane protein CASK	Homo sapiens (human)
negative regulation of cellular response to growth factor stimulus	Peripheral plasma membrane protein CASK	Homo sapiens (human)
regulation of synaptic vesicle exocytosis	Peripheral plasma membrane protein CASK	Homo sapiens (human)
protein localization	Peripheral plasma membrane protein CASK	Homo sapiens (human)
regulation of neurotransmitter secretion	Peripheral plasma membrane protein CASK	Homo sapiens (human)
protein phosphorylation	Aurora kinase A	Homo sapiens (human)
response to wounding	Aurora kinase A	Homo sapiens (human)
liver regeneration	Aurora kinase A	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
chromatin remodeling	Aurora kinase A	Homo sapiens (human)
protein phosphorylation	Aurora kinase A	Homo sapiens (human)
apoptotic process	Aurora kinase A	Homo sapiens (human)
spindle organization	Aurora kinase A	Homo sapiens (human)
spindle assembly involved in female meiosis I	Aurora kinase A	Homo sapiens (human)
mitotic centrosome separation	Aurora kinase A	Homo sapiens (human)
anterior/posterior axis specification	Aurora kinase A	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
negative regulation of gene expression	Aurora kinase A	Homo sapiens (human)
peptidyl-serine phosphorylation	Aurora kinase A	Homo sapiens (human)
regulation of protein stability	Aurora kinase A	Homo sapiens (human)
negative regulation of protein binding	Aurora kinase A	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Aurora kinase A	Homo sapiens (human)
negative regulation of apoptotic process	Aurora kinase A	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Aurora kinase A	Homo sapiens (human)
positive regulation of mitotic nuclear division	Aurora kinase A	Homo sapiens (human)
positive regulation of mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
regulation of centrosome cycle	Aurora kinase A	Homo sapiens (human)
protein autophosphorylation	Aurora kinase A	Homo sapiens (human)
cell division	Aurora kinase A	Homo sapiens (human)
centrosome localization	Aurora kinase A	Homo sapiens (human)
cilium disassembly	Aurora kinase A	Homo sapiens (human)
protein localization to centrosome	Aurora kinase A	Homo sapiens (human)
positive regulation of mitochondrial fission	Aurora kinase A	Homo sapiens (human)
positive regulation of oocyte maturation	Aurora kinase A	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Aurora kinase A	Homo sapiens (human)
neuron projection extension	Aurora kinase A	Homo sapiens (human)
mitotic spindle organization	Aurora kinase A	Homo sapiens (human)
regulation of cytokinesis	Aurora kinase A	Homo sapiens (human)
receptor-mediated endocytosis	Cyclin-G-associated kinase	Homo sapiens (human)
endoplasmic reticulum organization	Cyclin-G-associated kinase	Homo sapiens (human)
Golgi organization	Cyclin-G-associated kinase	Homo sapiens (human)
negative regulation of neuron projection development	Cyclin-G-associated kinase	Homo sapiens (human)
synaptic vesicle uncoating	Cyclin-G-associated kinase	Homo sapiens (human)
protein localization to Golgi apparatus	Cyclin-G-associated kinase	Homo sapiens (human)
intracellular transport	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin coat assembly	Cyclin-G-associated kinase	Homo sapiens (human)
chaperone cofactor-dependent protein refolding	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin coat disassembly	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin-dependent endocytosis	Cyclin-G-associated kinase	Homo sapiens (human)
protein localization to plasma membrane	Cyclin-G-associated kinase	Homo sapiens (human)
Golgi to lysosome transport	Cyclin-G-associated kinase	Homo sapiens (human)
regulation of clathrin coat assembly	Cyclin-G-associated kinase	Homo sapiens (human)
neuron migration	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
nervous system development	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
central nervous system development	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
response to virus	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
endosomal transport	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
central nervous system projection neuron axonogenesis	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
forebrain development	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
protein localization to nucleus	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
axon extension	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
dendrite morphogenesis	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
negative regulation of protein localization to nucleus	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
neuron projection morphogenesis	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
skeletal muscle contraction	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
inflammatory response	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
immune response	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
I-kappaB phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
Rho protein signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to xenobiotic stimulus	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to virus	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to toxic substance	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
anatomical structure morphogenesis	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to acetate	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to lipopolysaccharide	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
positive regulation of interferon-alpha production	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to hydroperoxide	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cellular response to reactive oxygen species	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
non-canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to amino acid	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
innate immune response	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
positive regulation of DNA-templated transcription	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
striated muscle cell differentiation	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
response to cholecystokinin	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cellular response to cadmium ion	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cellular response to tumor necrosis factor	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cellular response to virus	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
positive regulation of protein phosphorylation	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
neuromuscular junction development	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
memory	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
regulation of synaptic assembly at neuromuscular junction	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
positive regulation of gene expression	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
cell differentiation	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
protein autophosphorylation	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
skeletal muscle acetylcholine-gated channel clustering	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
positive regulation of protein geranylgeranylation	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
multicellular organism development	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
positive regulation of kinase activity	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
positive regulation of neuron projection development	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 6	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 6	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 6	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA oxidase	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
lipid homeostasis	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
response to osmotic stress	Mitogen-activated protein kinase 13	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 13	Homo sapiens (human)
positive regulation of interleukin-6 production	Mitogen-activated protein kinase 13	Homo sapiens (human)
cellular response to UV	Mitogen-activated protein kinase 13	Homo sapiens (human)
positive regulation of inflammatory response	Mitogen-activated protein kinase 13	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 13	Homo sapiens (human)
cellular response to hydrogen peroxide	Mitogen-activated protein kinase 13	Homo sapiens (human)
cellular response to interleukin-1	Mitogen-activated protein kinase 13	Homo sapiens (human)
cellular response to sorbitol	Mitogen-activated protein kinase 13	Homo sapiens (human)
cellular response to anisomycin	Mitogen-activated protein kinase 13	Homo sapiens (human)
cellular response to sodium arsenite	Mitogen-activated protein kinase 13	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 13	Homo sapiens (human)
intracellular signal transduction	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
type B pancreatic cell development	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
protein phosphorylation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
negative regulation of protein kinase activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
hyperosmotic response	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
insulin receptor signaling pathway	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of phospholipase activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
negative regulation of cardiac muscle cell apoptotic process	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cell migration	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
calcium-mediated signaling	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
actin cytoskeleton organization	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathway	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
T cell costimulation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
activation of protein kinase B activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cellular response to insulin stimulus	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
negative regulation of toll-like receptor signaling pathway	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
regulation of canonical NF-kappaB signal transduction	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
regulation of mast cell degranulation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of angiogenesis	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
protein autophosphorylation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of release of sequestered calcium ion into cytosol	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
extrinsic apoptotic signaling pathway	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of sprouting angiogenesis	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
positive regulation of vascular endothelial cell proliferation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
intracellular signal transduction	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
positive regulation of neuron maturation	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
positive regulation of axon extension	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
positive regulation of neuron projection arborization	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
positive regulation of branching morphogenesis of a nerve	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
chromatin organization	Death-associated protein kinase 3	Homo sapiens (human)
regulation of DNA-templated transcription	Death-associated protein kinase 3	Homo sapiens (human)
protein phosphorylation	Death-associated protein kinase 3	Homo sapiens (human)
apoptotic process	Death-associated protein kinase 3	Homo sapiens (human)
regulation of smooth muscle contraction	Death-associated protein kinase 3	Homo sapiens (human)
regulation of mitotic nuclear division	Death-associated protein kinase 3	Homo sapiens (human)
regulation of mitotic cell cycle	Death-associated protein kinase 3	Homo sapiens (human)
regulation of cell shape	Death-associated protein kinase 3	Homo sapiens (human)
regulation of autophagy	Death-associated protein kinase 3	Homo sapiens (human)
negative regulation of translation	Death-associated protein kinase 3	Homo sapiens (human)
positive regulation of cell migration	Death-associated protein kinase 3	Homo sapiens (human)
regulation of actin cytoskeleton organization	Death-associated protein kinase 3	Homo sapiens (human)
intracellular signal transduction	Death-associated protein kinase 3	Homo sapiens (human)
regulation of apoptotic process	Death-associated protein kinase 3	Homo sapiens (human)
positive regulation of apoptotic process	Death-associated protein kinase 3	Homo sapiens (human)
regulation of myosin II filament organization	Death-associated protein kinase 3	Homo sapiens (human)
protein autophosphorylation	Death-associated protein kinase 3	Homo sapiens (human)
regulation of focal adhesion assembly	Death-associated protein kinase 3	Homo sapiens (human)
cellular response to type II interferon	Death-associated protein kinase 3	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Death-associated protein kinase 3	Homo sapiens (human)
apoptotic signaling pathway	Death-associated protein kinase 3	Homo sapiens (human)
regulation of cell motility	Death-associated protein kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of T cell cytokine production	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
cytoplasmic pattern recognition receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
chromatin remodeling	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
inflammatory response	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
canonical NF-kappaB signal transduction	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
I-kappaB phosphorylation	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
negative regulation of gene expression	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of macroautophagy	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of interleukin-2 production	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
toll-like receptor 3 signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
TRIF-dependent toll-like receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
interleukin-33-mediated signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
interleukin-17A-mediated signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
defense response to bacterium	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
anoikis	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of cell cycle	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of cell size	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
T cell receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
cellular response to hypoxia	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
cellular response to angiotensin	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell migration	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
immune response	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
toll-like receptor 2 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of cytokine-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
adaptive immune response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of T-helper 1 type immune response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
apoptotic process	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
inflammatory response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
JNK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytokine-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein ubiquitination	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of chemokine production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interferon-alpha production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interferon-beta production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of type II interferon production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-1 beta production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-12 production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-2 production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-6 production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
immature T cell proliferation in thymus	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of immature T cell proliferation in thymus	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
CD4-positive, alpha-beta T cell proliferation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
defense response to bacterium	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of apoptotic process	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to exogenous dsRNA	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
innate immune response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of T-helper 1 cell differentiation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of JNK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
defense response to Gram-positive bacterium	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
T cell receptor signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein homooligomerization	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
stress-activated MAPK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of macrophage cytokine production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
ERK1 and ERK2 cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
nucleotide-binding oligomerization domain containing 1 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
nucleotide-binding oligomerization domain containing 2 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to interleukin-1	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to interleukin-12	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to interleukin-18	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to lipoteichoic acid	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to peptidoglycan	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to muramyl dipeptide	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
activation of cysteine-type endopeptidase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
xenophagy	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein K63-linked ubiquitination	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of xenophagy	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
estrous cycle	Carbonic anhydrase 12	Homo sapiens (human)
chloride ion homeostasis	Carbonic anhydrase 12	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 12	Homo sapiens (human)
chromatin remodeling	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
apoptotic process	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
chromosome segregation	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
regulation of sister chromatid cohesion	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
mitotic spindle assembly checkpoint signaling	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
cell division	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
regulation of chromosome segregation	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
meiotic sister chromatid cohesion, centromeric	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein phosphorylation	NUAK family SNF1-like kinase 1	Homo sapiens (human)
DNA damage response	NUAK family SNF1-like kinase 1	Homo sapiens (human)
cell adhesion	NUAK family SNF1-like kinase 1	Homo sapiens (human)
regulation of cell adhesion	NUAK family SNF1-like kinase 1	Homo sapiens (human)
regulation of myosin-light-chain-phosphatase activity	NUAK family SNF1-like kinase 1	Homo sapiens (human)
regulation of cell population proliferation	NUAK family SNF1-like kinase 1	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	NUAK family SNF1-like kinase 1	Homo sapiens (human)
regulation of cellular senescence	NUAK family SNF1-like kinase 1	Homo sapiens (human)
mitochondrion organization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial genome maintenance	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial fission	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
neural tube closure	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
apoptotic process	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrion organization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
inner mitochondrial membrane organization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
visual perception	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial fusion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
axonal transport of mitochondrion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
positive regulation of interleukin-17 production	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cristae formation	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
negative regulation of apoptotic process	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTP metabolic process	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
protein complex oligomerization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane fusion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
negative regulation of release of cytochrome c from mitochondria	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cellular senescence	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane tubulation	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane fusion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
positive regulation of T-helper 17 cell lineage commitment	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
phosphatidylinositol biosynthetic process	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
phagocytosis	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
synaptic vesicle exocytosis	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
actin cytoskeleton organization	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
neutrophil chemotaxis	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
adherens junction assembly	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
synaptic vesicle endocytosis	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
membrane organization	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
clathrin-dependent endocytosis	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
cell-cell adhesion	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
positive regulation of platelet aggregation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of platelet activation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to antibiotic	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
microglial cell activation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
chromatin remodeling	Tyrosine-protein kinase JAK2	Homo sapiens (human)
transcription by RNA polymerase II	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
immune response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
enzyme-linked receptor protein signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK2	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of cardiac muscle cell apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cell-substrate adhesion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to amine	Tyrosine-protein kinase JAK2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of cell-cell adhesion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
actin filament polymerization	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
erythrocyte differentiation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase JAK2	Homo sapiens (human)
axon regeneration	Tyrosine-protein kinase JAK2	Homo sapiens (human)
intracellular mineralocorticoid receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of insulin secretion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to lipopolysaccharide	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of type II interferon production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of interleukin-1 beta production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of interleukin-17 production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of natural killer cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to hydroperoxide	Tyrosine-protein kinase JAK2	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
symbiont-induced defense-related programmed cell death	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to tumor necrosis factor	Tyrosine-protein kinase JAK2	Homo sapiens (human)
post-embryonic hemopoiesis	Tyrosine-protein kinase JAK2	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-12-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to interleukin-3	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-5-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
collagen-activated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-3-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
granulocyte-macrophage colony-stimulating factor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of T cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of protein import into nucleus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK2	Homo sapiens (human)
activation of Janus kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of DNA binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of neuron apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
post-translational protein modification	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of MHC class II biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of nitric oxide biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cell differentiation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of inflammatory response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
modulation of chemical synaptic transmission	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of NK T cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
growth hormone receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of growth hormone receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
mammary gland epithelium development	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of leukocyte proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to interleukin-12	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-35-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to lipopolysaccharide	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to dexamethasone stimulus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to virus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of epithelial cell apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of postsynapse to nucleus signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of signaling receptor activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
visual perception	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
detection of light stimulus involved in visual perception	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
calcium ion import across plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
regulation of translational initiation	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
ribosome assembly	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
translational initiation	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
epithelial to mesenchymal transition	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Rho-associated protein kinase 2	Homo sapiens (human)
response to ischemia	Rho-associated protein kinase 2	Homo sapiens (human)
aortic valve morphogenesis	Rho-associated protein kinase 2	Homo sapiens (human)
protein phosphorylation	Rho-associated protein kinase 2	Homo sapiens (human)
smooth muscle contraction	Rho-associated protein kinase 2	Homo sapiens (human)
canonical NF-kappaB signal transduction	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of endothelial cell migration	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of gene expression	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of gene expression	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of centrosome duplication	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of angiogenesis	Rho-associated protein kinase 2	Homo sapiens (human)
actin cytoskeleton organization	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cell adhesion	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of cell migration	Rho-associated protein kinase 2	Homo sapiens (human)
cortical actin cytoskeleton organization	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of nervous system process	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of connective tissue growth factor production	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of actin cytoskeleton organization	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of myosin-light-chain-phosphatase activity	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of circadian rhythm	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of MAPK cascade	Rho-associated protein kinase 2	Homo sapiens (human)
modulation by host of viral process	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of nitric oxide biosynthetic process	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of keratinocyte differentiation	Rho-associated protein kinase 2	Homo sapiens (human)
rhythmic process	Rho-associated protein kinase 2	Homo sapiens (human)
centrosome duplication	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of stress fiber assembly	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of stress fiber assembly	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of focal adhesion assembly	Rho-associated protein kinase 2	Homo sapiens (human)
mRNA destabilization	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of biomineral tissue development	Rho-associated protein kinase 2	Homo sapiens (human)
cellular response to testosterone stimulus	Rho-associated protein kinase 2	Homo sapiens (human)
response to transforming growth factor beta	Rho-associated protein kinase 2	Homo sapiens (human)
protein localization to plasma membrane	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of fibroblast growth factor production	Rho-associated protein kinase 2	Homo sapiens (human)
blood vessel diameter maintenance	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of angiotensin-activated signaling pathway	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of protein localization to lysosome	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cellular response to hypoxia	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of amyloid-beta formation	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of protein localization to early endosome	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of amyloid precursor protein catabolic process	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of establishment of endothelial barrier	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of bicellular tight junction assembly	Rho-associated protein kinase 2	Homo sapiens (human)
cellular response to acetylcholine	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of connective tissue replacement	Rho-associated protein kinase 2	Homo sapiens (human)
response to angiotensin	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of establishment of cell polarity	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cell motility	Rho-associated protein kinase 2	Homo sapiens (human)
actomyosin structure organization	Rho-associated protein kinase 2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Rho-associated protein kinase 2	Homo sapiens (human)
mitotic cytokinesis	Rho-associated protein kinase 2	Homo sapiens (human)
embryonic morphogenesis	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cell junction assembly	Rho-associated protein kinase 2	Homo sapiens (human)
Rho protein signal transduction	Rho-associated protein kinase 2	Homo sapiens (human)
autophagosome assembly	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein localization	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
negative regulation of cell population proliferation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
macroautophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
regulation of macroautophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
neuron projection regeneration	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
neuron projection development	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cellular response to nutrient levels	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
response to starvation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
regulation of protein lipidation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
positive regulation of autophagosome assembly	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
axon extension	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
reticulophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
piecemeal microautophagy of the nucleus	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
negative regulation of collateral sprouting	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
endothelial cell proliferation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
mRNA catabolic process	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
regulation of macroautophagy	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of RNA splicing	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to unfolded protein	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
peptidyl-serine autophosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
IRE1-mediated unfolded protein response	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of JUN kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
mRNA splicing, via endonucleolytic cleavage and ligation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to hydrogen peroxide	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to glucose stimulus	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of endoplasmic reticulum unfolded protein response	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
insulin metabolic process	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
peptidyl-serine trans-autophosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
negative regulation of cytokine production	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
chromatin remodeling	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein phosphorylation	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
inflammatory response	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
axon guidance	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
post-translational protein modification	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
negative regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
regulation of postsynapse organization	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
cis assembly of pre-catalytic spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
mRNA splicing, via spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
osteoblast differentiation	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
negative regulation of cytokine production	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
chromatin remodeling	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein phosphorylation	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
inflammatory response	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
post-translational protein modification	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 16	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Serine/threonine-protein kinase 16	Homo sapiens (human)
chemotaxis	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
phosphatidylinositol-3-phosphate biosynthetic process	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
modulation by host of viral process	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
cell migration	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
histamine metabolic process	Solute carrier family 22 member 3	Homo sapiens (human)
organic cation transport	Solute carrier family 22 member 3	Homo sapiens (human)
quaternary ammonium group transport	Solute carrier family 22 member 3	Homo sapiens (human)
monoatomic ion transport	Solute carrier family 22 member 3	Homo sapiens (human)
neurotransmitter transport	Solute carrier family 22 member 3	Homo sapiens (human)
serotonin transport	Solute carrier family 22 member 3	Homo sapiens (human)
organic cation transport	Solute carrier family 22 member 3	Homo sapiens (human)
quaternary ammonium group transport	Solute carrier family 22 member 3	Homo sapiens (human)
organic anion transport	Solute carrier family 22 member 3	Homo sapiens (human)
monocarboxylic acid transport	Solute carrier family 22 member 3	Homo sapiens (human)
monoamine transport	Solute carrier family 22 member 3	Homo sapiens (human)
spermidine transport	Solute carrier family 22 member 3	Homo sapiens (human)
dopamine transport	Solute carrier family 22 member 3	Homo sapiens (human)
norepinephrine transport	Solute carrier family 22 member 3	Homo sapiens (human)
regulation of appetite	Solute carrier family 22 member 3	Homo sapiens (human)
xenobiotic transport	Solute carrier family 22 member 3	Homo sapiens (human)
epinephrine transport	Solute carrier family 22 member 3	Homo sapiens (human)
histamine transport	Solute carrier family 22 member 3	Homo sapiens (human)
serotonin uptake	Solute carrier family 22 member 3	Homo sapiens (human)
histamine uptake	Solute carrier family 22 member 3	Homo sapiens (human)
norepinephrine uptake	Solute carrier family 22 member 3	Homo sapiens (human)
epinephrine uptake	Solute carrier family 22 member 3	Homo sapiens (human)
purine-containing compound transmembrane transport	Solute carrier family 22 member 3	Homo sapiens (human)
dopamine uptake	Solute carrier family 22 member 3	Homo sapiens (human)
transport across blood-brain barrier	Solute carrier family 22 member 3	Homo sapiens (human)
spermidine transmembrane transport	Solute carrier family 22 member 3	Homo sapiens (human)
cellular detoxification	Solute carrier family 22 member 3	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
dendrite development	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
regulation of actin filament polymerization	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
ephrin receptor signaling pathway	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
synapse organization	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
dendritic spine morphogenesis	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
cellular response to organic cyclic compound	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
regulation of postsynapse organization	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
neuron migration	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase-like 5	Homo sapiens (human)
positive regulation of GTPase activity	Cyclin-dependent kinase-like 5	Homo sapiens (human)
positive regulation of axon extension	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein autophosphorylation	Cyclin-dependent kinase-like 5	Homo sapiens (human)
regulation of dendrite development	Cyclin-dependent kinase-like 5	Homo sapiens (human)
positive regulation of dendrite morphogenesis	Cyclin-dependent kinase-like 5	Homo sapiens (human)
modulation of chemical synaptic transmission	Cyclin-dependent kinase-like 5	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase-like 5	Homo sapiens (human)
positive regulation of dendritic spine development	Cyclin-dependent kinase-like 5	Homo sapiens (human)
regulation of postsynapse organization	Cyclin-dependent kinase-like 5	Homo sapiens (human)
regulation of cilium assembly	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 17B	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 17B	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 17B	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 17B	Homo sapiens (human)
positive regulation of fibroblast apoptotic process	Serine/threonine-protein kinase 17B	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase 17B	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 10	Homo sapiens (human)
lymphocyte aggregation	Serine/threonine-protein kinase 10	Homo sapiens (human)
regulation of lymphocyte migration	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein kinase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D3	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D3	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D3	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 14	Homo sapiens (human)
Wnt signaling pathway	Cyclin-dependent kinase 14	Homo sapiens (human)
cell division	Cyclin-dependent kinase 14	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 14	Homo sapiens (human)
regulation of canonical Wnt signaling pathway	Cyclin-dependent kinase 14	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 14	Homo sapiens (human)
mitotic chromosome condensation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
meiotic chromosome condensation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
meiotic chromosome segregation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cell division	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
kinetochore organization	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
positive regulation of chromosome segregation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
positive regulation of chromosome separation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
positive regulation of chromosome condensation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
cellular response to stress	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cell volume homeostasis	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
response to oxidative stress	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
osmosensory signaling pathway	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
response to xenobiotic stimulus	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
positive regulation of T cell chemotaxis	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
chemokine (C-C motif) ligand 21 signaling pathway	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
chemokine (C-X-C motif) ligand 12 signaling pathway	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
renal sodium ion absorption	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cellular hyperosmotic response	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cellular hypotonic response	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
negative regulation of potassium ion transmembrane transport	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cellular response to chemokine	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
negative regulation of potassium ion transmembrane transporter activity	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
microvillus assembly	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
negative regulation of cell-matrix adhesion	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of cell migration	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of ARF protein signal transduction	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of hippo signaling	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
negative regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of GTPase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of keratinocyte migration	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of focal adhesion assembly	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of focal adhesion disassembly	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
regulation of MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
neuron projection morphogenesis	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
sister chromatid segregation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
inner cell mass cell fate commitment	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
inner cell mass cellular morphogenesis	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
hormone-mediated signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
keratinocyte differentiation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of actin filament polymerization	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of intracellular estrogen receptor signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of protein-containing complex assembly	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
negative regulation of cyclin-dependent protein serine/threonine kinase activity	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
cytoplasmic sequestering of protein	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
cell division	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
mammary gland epithelial cell differentiation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
negative regulation of protein localization to nucleus	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of organ growth	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
dendritic spine development	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cellular response to organic cyclic compound	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cell-cell adhesion	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
signal transduction in response to DNA damage	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
double-strand break repair	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
regulation of DNA-templated transcription	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein catabolic process	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
mitotic intra-S DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
regulation of protein catabolic process	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
signal transduction in response to DNA damage	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
thymocyte apoptotic process	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
cellular response to gamma radiation	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
mitotic spindle assembly	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
replicative senescence	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
regulation of autophagosome assembly	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
mitotic DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
response to oxidative stress	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of ubiquitin-protein transferase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of phospholipase C activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitotic cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neural tube closure	Tyrosine-protein kinase ABL1	Homo sapiens (human)
B-1 B cell homeostasis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of protein phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
B cell proliferation involved in immune response	Tyrosine-protein kinase ABL1	Homo sapiens (human)
transitional one stage B cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mismatch repair	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of DNA-templated transcription	Tyrosine-protein kinase ABL1	Homo sapiens (human)
autophagy	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DNA damage response	Tyrosine-protein kinase ABL1	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
associative learning	Tyrosine-protein kinase ABL1	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Tyrosine-protein kinase ABL1	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
post-embryonic development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of autophagy	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of endothelial cell migration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cerebellum morphogenesis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of cell-cell adhesion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
microspike assembly	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin cytoskeleton organization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin filament polymerization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of endocytosis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell adhesion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuron differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
BMP signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of BMP signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of axon extension	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of microtubule polymerization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of Cdc42 protein signal transduction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of type II interferon production	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of interleukin-2 production	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of osteoblast proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to oxidative stress	Tyrosine-protein kinase ABL1	Homo sapiens (human)
response to endoplasmic reticulum stress	Tyrosine-protein kinase ABL1	Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuropilin signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
signal transduction in response to DNA damage	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of neuron apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
endothelial cell migration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of T cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of vasoconstriction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of mitotic cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of mitotic cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase ABL1	Homo sapiens (human)
alpha-beta T cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of fibroblast proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
spleen development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
thymus development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
activated T cell proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuromuscular process controlling balance	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of release of sequestered calcium ion into cytosol	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of oxidoreductase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuron apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of ubiquitin-protein transferase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
myoblast proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of stress fiber assembly	Tyrosine-protein kinase ABL1	Homo sapiens (human)
establishment of localization in cell	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitochondrial depolarization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of focal adhesion assembly	Tyrosine-protein kinase ABL1	Homo sapiens (human)
Bergmann glial cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cardiac muscle cell proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuroepithelial cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase ABL1	Homo sapiens (human)
ERK1 and ERK2 cascade	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DNA conformation change	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to lipopolysaccharide	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
response to epinephrine	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of protein serine/threonine kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular senescence	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cell-cell adhesion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of dendrite development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of long-term synaptic potentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of hematopoietic stem cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of extracellular matrix organization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
podocyte apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to dopamine	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of establishment of T cell polarity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DN4 thymocyte differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein localization to cytoplasmic microtubule plus-end	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of microtubule binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of actin filament binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of modification of synaptic structure	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of blood vessel branching	Tyrosine-protein kinase ABL1	Homo sapiens (human)
activation of protein kinase C activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of double-strand break repair via homologous recombination	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of Wnt signaling pathway, planar cell polarity pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell motility	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of T cell migration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of cellular senescence	Tyrosine-protein kinase ABL1	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell cycle	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
negative regulation of extrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
epidermal growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
cell differentiation	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
negative regulation of intrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
progesterone receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
innate immune response	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
cell surface receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Epidermal growth factor receptor	Homo sapiens (human)
MAPK cascade	Epidermal growth factor receptor	Homo sapiens (human)
ossification	Epidermal growth factor receptor	Homo sapiens (human)
embryonic placenta development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
hair follicle development	Epidermal growth factor receptor	Homo sapiens (human)
translation	Epidermal growth factor receptor	Homo sapiens (human)
signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
activation of phospholipase C activity	Epidermal growth factor receptor	Homo sapiens (human)
salivary gland morphogenesis	Epidermal growth factor receptor	Homo sapiens (human)
midgut development	Epidermal growth factor receptor	Homo sapiens (human)
learning or memory	Epidermal growth factor receptor	Homo sapiens (human)
circadian rhythm	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Epidermal growth factor receptor	Homo sapiens (human)
diterpenoid metabolic process	Epidermal growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
cerebral cortex cell migration	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell growth	Epidermal growth factor receptor	Homo sapiens (human)
lung development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell migration	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of superoxide anion generation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
response to cobalamin	Epidermal growth factor receptor	Homo sapiens (human)
response to hydroxyisoflavone	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to reactive oxygen species	Epidermal growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
ERBB2-EGFR signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of epidermal growth factor receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of protein catabolic process	Epidermal growth factor receptor	Homo sapiens (human)
vasodilation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
ovulation cycle	Epidermal growth factor receptor	Homo sapiens (human)
hydrogen peroxide metabolic process	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of apoptotic process	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of MAP kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
tongue development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cyclin-dependent protein serine/threonine kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of DNA repair	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of DNA replication	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of bone resorption	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of DNA-templated transcription	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of vasoconstriction	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of mitotic cell cycle	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Epidermal growth factor receptor	Homo sapiens (human)
regulation of JNK cascade	Epidermal growth factor receptor	Homo sapiens (human)
symbiont entry into host cell	Epidermal growth factor receptor	Homo sapiens (human)
protein autophosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
astrocyte activation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of fibroblast proliferation	Epidermal growth factor receptor	Homo sapiens (human)
digestive tract morphogenesis	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
neuron projection morphogenesis	Epidermal growth factor receptor	Homo sapiens (human)
epithelial cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
protein insertion into membrane	Epidermal growth factor receptor	Homo sapiens (human)
response to calcium ion	Epidermal growth factor receptor	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of glial cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
morphogenesis of an epithelial fold	Epidermal growth factor receptor	Homo sapiens (human)
eyelid development in camera-type eye	Epidermal growth factor receptor	Homo sapiens (human)
response to UV-A	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of mucus secretion	Epidermal growth factor receptor	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to amino acid stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to mechanical stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to cadmium ion	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to estradiol stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to xenobiotic stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to dexamethasone stimulus	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
liver regeneration	Epidermal growth factor receptor	Homo sapiens (human)
cell-cell adhesion	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of protein kinase C activity	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of prolactin secretion	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of miRNA transcription	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of cardiocyte differentiation	Epidermal growth factor receptor	Homo sapiens (human)
neurogenesis	Epidermal growth factor receptor	Homo sapiens (human)
multicellular organism development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 1	Homo sapiens (human)
morphogenesis of an epithelium	Carbonic anhydrase 2	Homo sapiens (human)
positive regulation of synaptic transmission, GABAergic	Carbonic anhydrase 2	Homo sapiens (human)
positive regulation of cellular pH reduction	Carbonic anhydrase 2	Homo sapiens (human)
angiotensin-activated signaling pathway	Carbonic anhydrase 2	Homo sapiens (human)
regulation of monoatomic anion transport	Carbonic anhydrase 2	Homo sapiens (human)
secretion	Carbonic anhydrase 2	Homo sapiens (human)
regulation of intracellular pH	Carbonic anhydrase 2	Homo sapiens (human)
neuron cellular homeostasis	Carbonic anhydrase 2	Homo sapiens (human)
positive regulation of dipeptide transmembrane transport	Carbonic anhydrase 2	Homo sapiens (human)
regulation of chloride transport	Carbonic anhydrase 2	Homo sapiens (human)
carbon dioxide transport	Carbonic anhydrase 2	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 2	Homo sapiens (human)
negative regulation of receptor recycling	Low-density lipoprotein receptor	Homo sapiens (human)
lipid metabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
endocytosis	Low-density lipoprotein receptor	Homo sapiens (human)
receptor-mediated endocytosis	Low-density lipoprotein receptor	Homo sapiens (human)
phagocytosis	Low-density lipoprotein receptor	Homo sapiens (human)
long-term memory	Low-density lipoprotein receptor	Homo sapiens (human)
cholesterol metabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
positive regulation of gene expression	Low-density lipoprotein receptor	Homo sapiens (human)
negative regulation of gene expression	Low-density lipoprotein receptor	Homo sapiens (human)
positive regulation of triglyceride biosynthetic process	Low-density lipoprotein receptor	Homo sapiens (human)
regulation of phosphatidylcholine catabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
negative regulation of low-density lipoprotein particle clearance	Low-density lipoprotein receptor	Homo sapiens (human)
phospholipid transport	Low-density lipoprotein receptor	Homo sapiens (human)
intestinal cholesterol absorption	Low-density lipoprotein receptor	Homo sapiens (human)
cholesterol transport	Low-density lipoprotein receptor	Homo sapiens (human)
plasma lipoprotein particle clearance	Low-density lipoprotein receptor	Homo sapiens (human)
low-density lipoprotein particle clearance	Low-density lipoprotein receptor	Homo sapiens (human)
high-density lipoprotein particle clearance	Low-density lipoprotein receptor	Homo sapiens (human)
lipoprotein catabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
cholesterol homeostasis	Low-density lipoprotein receptor	Homo sapiens (human)
symbiont entry into host cell	Low-density lipoprotein receptor	Homo sapiens (human)
artery morphogenesis	Low-density lipoprotein receptor	Homo sapiens (human)
positive regulation of inflammatory response	Low-density lipoprotein receptor	Homo sapiens (human)
regulation of protein metabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
negative regulation of protein metabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
response to caloric restriction	Low-density lipoprotein receptor	Homo sapiens (human)
negative regulation of astrocyte activation	Low-density lipoprotein receptor	Homo sapiens (human)
cholesterol import	Low-density lipoprotein receptor	Homo sapiens (human)
cellular response to fatty acid	Low-density lipoprotein receptor	Homo sapiens (human)
cellular response to low-density lipoprotein particle stimulus	Low-density lipoprotein receptor	Homo sapiens (human)
receptor-mediated endocytosis involved in cholesterol transport	Low-density lipoprotein receptor	Homo sapiens (human)
regulation of cholesterol metabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
amyloid-beta clearance	Low-density lipoprotein receptor	Homo sapiens (human)
amyloid-beta clearance by cellular catabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
negative regulation of microglial cell activation	Low-density lipoprotein receptor	Homo sapiens (human)
positive regulation of lysosomal protein catabolic process	Low-density lipoprotein receptor	Homo sapiens (human)
negative regulation of amyloid fibril formation	Low-density lipoprotein receptor	Homo sapiens (human)
angiogenesis	Fibronectin	Homo sapiens (human)
regulation of protein phosphorylation	Fibronectin	Homo sapiens (human)
acute-phase response	Fibronectin	Homo sapiens (human)
cell adhesion	Fibronectin	Homo sapiens (human)
calcium-independent cell-matrix adhesion	Fibronectin	Homo sapiens (human)
integrin-mediated signaling pathway	Fibronectin	Homo sapiens (human)
positive regulation of cell population proliferation	Fibronectin	Homo sapiens (human)
regulation of cell shape	Fibronectin	Homo sapiens (human)
response to wounding	Fibronectin	Homo sapiens (human)
positive regulation of gene expression	Fibronectin	Homo sapiens (human)
peptide cross-linking	Fibronectin	Homo sapiens (human)
integrin activation	Fibronectin	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Fibronectin	Homo sapiens (human)
endodermal cell differentiation	Fibronectin	Homo sapiens (human)
wound healing	Fibronectin	Homo sapiens (human)
positive regulation of axon extension	Fibronectin	Homo sapiens (human)
positive regulation of fibroblast proliferation	Fibronectin	Homo sapiens (human)
biological process involved in interaction with symbiont	Fibronectin	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Fibronectin	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Fibronectin	Homo sapiens (human)
negative regulation of transforming growth factor beta production	Fibronectin	Homo sapiens (human)
negative regulation of monocyte activation	Fibronectin	Homo sapiens (human)
neural crest cell migration involved in autonomic nervous system development	Fibronectin	Homo sapiens (human)
positive regulation of substrate-dependent cell migration, cell attachment to substrate	Fibronectin	Homo sapiens (human)
nervous system development	Fibronectin	Homo sapiens (human)
cell-matrix adhesion	Fibronectin	Homo sapiens (human)
cell-substrate junction assembly	Fibronectin	Homo sapiens (human)
heart development	Fibronectin	Homo sapiens (human)
apoptotic process	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
activation of adenylate cyclase activity	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cell population proliferation	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
insulin receptor signaling pathway	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
Schwann cell development	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
thyroid gland development	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein-containing complex assembly	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
somatic stem cell population maintenance	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
regulation of Rho protein signal transduction	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
insulin secretion involved in cellular response to glucose stimulus	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
response to muscle stretch	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
wound healing	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
myelination	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
regulation of apoptotic process	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of apoptotic process	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of MAPK cascade	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
type B pancreatic cell proliferation	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
intermediate filament cytoskeleton organization	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell differentiation	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
neurotrophin TRK receptor signaling pathway	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
thymus development	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
face development	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
type II interferon-mediated signaling pathway	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
death-inducing signaling complex assembly	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell motility	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
MAPK cascade	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
cell surface receptor signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of protein phosphorylation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
protein phosphorylation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
signal transduction	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
enzyme-linked receptor protein signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
heart development	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
neuromuscular junction development	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
motor neuron axon guidance	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
Schwann cell development	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of cell growth	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
regulation of microtubule-based process	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
immature T cell proliferation in thymus	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
negative regulation of immature T cell proliferation in thymus	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
intracellular signal transduction	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ERBB2-EGFR signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ERBB2-ERBB4 signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
wound healing	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
myelination	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of MAP kinase activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of translation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
regulation of angiogenesis	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of cell adhesion	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase I	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
oligodendrocyte differentiation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
cellular response to growth factor stimulus	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
semaphorin-plexin signaling pathway	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of protein targeting to membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
neurotransmitter receptor localization to postsynaptic specialization membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
neurogenesis	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of MAPK cascade	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
negative regulation of apoptotic process	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of kinase activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
multicellular organism development	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
positive regulation of cell population proliferation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
neuron differentiation	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
cellular response to amyloid-beta	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
protein phosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
axon guidance	High affinity nerve growth factor receptor	Homo sapiens (human)
learning or memory	High affinity nerve growth factor receptor	Homo sapiens (human)
circadian rhythm	High affinity nerve growth factor receptor	Homo sapiens (human)
negative regulation of cell population proliferation	High affinity nerve growth factor receptor	Homo sapiens (human)
response to xenobiotic stimulus	High affinity nerve growth factor receptor	Homo sapiens (human)
programmed cell death involved in cell development	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of neuron projection development	High affinity nerve growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
olfactory nerve development	High affinity nerve growth factor receptor	Homo sapiens (human)
B cell differentiation	High affinity nerve growth factor receptor	Homo sapiens (human)
response to nutrient levels	High affinity nerve growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
nerve growth factor signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
mechanoreceptor differentiation	High affinity nerve growth factor receptor	Homo sapiens (human)
negative regulation of apoptotic process	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of programmed cell death	High affinity nerve growth factor receptor	Homo sapiens (human)
negative regulation of neuron apoptotic process	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of GTPase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of Ras protein signal transduction	High affinity nerve growth factor receptor	Homo sapiens (human)
protein autophosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin TRK receptor signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
ephrin receptor signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
sympathetic nervous system development	High affinity nerve growth factor receptor	Homo sapiens (human)
response to axon injury	High affinity nerve growth factor receptor	Homo sapiens (human)
detection of temperature stimulus involved in sensory perception of pain	High affinity nerve growth factor receptor	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of pain	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
neuron apoptotic process	High affinity nerve growth factor receptor	Homo sapiens (human)
response to hydrostatic pressure	High affinity nerve growth factor receptor	Homo sapiens (human)
response to electrical stimulus	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of synapse assembly	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	High affinity nerve growth factor receptor	Homo sapiens (human)
Sertoli cell development	High affinity nerve growth factor receptor	Homo sapiens (human)
axonogenesis involved in innervation	High affinity nerve growth factor receptor	Homo sapiens (human)
behavioral response to formalin induced pain	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	High affinity nerve growth factor receptor	Homo sapiens (human)
cellular response to nicotine	High affinity nerve growth factor receptor	Homo sapiens (human)
cellular response to nerve growth factor stimulus	High affinity nerve growth factor receptor	Homo sapiens (human)
multicellular organism development	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	High affinity nerve growth factor receptor	Homo sapiens (human)
chromosome segregation	ADP/ATP translocase 2	Homo sapiens (human)
positive regulation of cell population proliferation	ADP/ATP translocase 2	Homo sapiens (human)
adenine transport	ADP/ATP translocase 2	Homo sapiens (human)
B cell differentiation	ADP/ATP translocase 2	Homo sapiens (human)
erythrocyte differentiation	ADP/ATP translocase 2	Homo sapiens (human)
regulation of mitochondrial membrane permeability	ADP/ATP translocase 2	Homo sapiens (human)
adenine nucleotide transport	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial ADP transmembrane transport	ADP/ATP translocase 2	Homo sapiens (human)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ADP/ATP translocase 2	Homo sapiens (human)
positive regulation of mitophagy	ADP/ATP translocase 2	Homo sapiens (human)
proton transmembrane transport	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial ATP transmembrane transport	ADP/ATP translocase 2	Homo sapiens (human)
cellular response to leukemia inhibitory factor	ADP/ATP translocase 2	Homo sapiens (human)
adaptive thermogenesis	ADP/ATP translocase 2	Homo sapiens (human)
adaptive immune response	Protein kinase C beta type	Homo sapiens (human)
chromatin remodeling	Protein kinase C beta type	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Protein kinase C beta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C beta type	Homo sapiens (human)
calcium ion transport	Protein kinase C beta type	Homo sapiens (human)
intracellular calcium ion homeostasis	Protein kinase C beta type	Homo sapiens (human)
apoptotic process	Protein kinase C beta type	Homo sapiens (human)
mitotic nuclear membrane disassembly	Protein kinase C beta type	Homo sapiens (human)
signal transduction	Protein kinase C beta type	Homo sapiens (human)
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
response to xenobiotic stimulus	Protein kinase C beta type	Homo sapiens (human)
response to glucose	Protein kinase C beta type	Homo sapiens (human)
regulation of glucose transmembrane transport	Protein kinase C beta type	Homo sapiens (human)
negative regulation of glucose transmembrane transport	Protein kinase C beta type	Homo sapiens (human)
regulation of dopamine secretion	Protein kinase C beta type	Homo sapiens (human)
dibenzo-p-dioxin metabolic process	Protein kinase C beta type	Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C beta type	Homo sapiens (human)
response to vitamin D	Protein kinase C beta type	Homo sapiens (human)
regulation of growth	Protein kinase C beta type	Homo sapiens (human)
B cell activation	Protein kinase C beta type	Homo sapiens (human)
positive regulation of odontogenesis of dentin-containing tooth	Protein kinase C beta type	Homo sapiens (human)
lipoprotein transport	Protein kinase C beta type	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Protein kinase C beta type	Homo sapiens (human)
post-translational protein modification	Protein kinase C beta type	Homo sapiens (human)
response to ethanol	Protein kinase C beta type	Homo sapiens (human)
positive regulation of angiogenesis	Protein kinase C beta type	Homo sapiens (human)
positive regulation of DNA-templated transcription	Protein kinase C beta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
B cell receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
positive regulation of B cell receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
cellular response to carbohydrate stimulus	Protein kinase C beta type	Homo sapiens (human)
presynaptic modulation of chemical synaptic transmission	Protein kinase C beta type	Homo sapiens (human)
regulation of synaptic vesicle exocytosis	Protein kinase C beta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C beta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C beta type	Homo sapiens (human)
positive regulation of MAP kinase activity	Insulin receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Insulin receptor	Homo sapiens (human)
positive regulation of receptor internalization	Insulin receptor	Homo sapiens (human)
heart morphogenesis	Insulin receptor	Homo sapiens (human)
regulation of DNA-templated transcription	Insulin receptor	Homo sapiens (human)
protein phosphorylation	Insulin receptor	Homo sapiens (human)
receptor-mediated endocytosis	Insulin receptor	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Insulin receptor	Homo sapiens (human)
learning	Insulin receptor	Homo sapiens (human)
memory	Insulin receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Insulin receptor	Homo sapiens (human)
insulin receptor signaling pathway	Insulin receptor	Homo sapiens (human)
epidermis development	Insulin receptor	Homo sapiens (human)
male gonad development	Insulin receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Insulin receptor	Homo sapiens (human)
male sex determination	Insulin receptor	Homo sapiens (human)
adrenal gland development	Insulin receptor	Homo sapiens (human)
positive regulation of cell migration	Insulin receptor	Homo sapiens (human)
exocrine pancreas development	Insulin receptor	Homo sapiens (human)
receptor internalization	Insulin receptor	Homo sapiens (human)
activation of protein kinase activity	Insulin receptor	Homo sapiens (human)
activation of protein kinase B activity	Insulin receptor	Homo sapiens (human)
cellular response to insulin stimulus	Insulin receptor	Homo sapiens (human)
glucose homeostasis	Insulin receptor	Homo sapiens (human)
positive regulation of protein-containing complex disassembly	Insulin receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Insulin receptor	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Insulin receptor	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	Insulin receptor	Homo sapiens (human)
positive regulation of glycolytic process	Insulin receptor	Homo sapiens (human)
positive regulation of mitotic nuclear division	Insulin receptor	Homo sapiens (human)
positive regulation of DNA-templated transcription	Insulin receptor	Homo sapiens (human)
regulation of embryonic development	Insulin receptor	Homo sapiens (human)
positive regulation of glucose import	Insulin receptor	Homo sapiens (human)
symbiont entry into host cell	Insulin receptor	Homo sapiens (human)
protein autophosphorylation	Insulin receptor	Homo sapiens (human)
positive regulation of developmental growth	Insulin receptor	Homo sapiens (human)
positive regulation of meiotic cell cycle	Insulin receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin receptor	Homo sapiens (human)
positive regulation of respiratory burst	Insulin receptor	Homo sapiens (human)
cellular response to growth factor stimulus	Insulin receptor	Homo sapiens (human)
dendritic spine maintenance	Insulin receptor	Homo sapiens (human)
amyloid-beta clearance	Insulin receptor	Homo sapiens (human)
transport across blood-brain barrier	Insulin receptor	Homo sapiens (human)
neuron projection maintenance	Insulin receptor	Homo sapiens (human)
regulation of female gonad development	Insulin receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Insulin receptor	Homo sapiens (human)
multicellular organism development	Insulin receptor	Homo sapiens (human)
positive regulation of kinase activity	Insulin receptor	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
intracellular zinc ion homeostasis	Tyrosine-protein kinase Lck	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase Lck	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase Lck	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
hemopoiesis	Tyrosine-protein kinase Lck	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell differentiation	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of heterotypic cell-cell adhesion	Tyrosine-protein kinase Lck	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Lck	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
Fc-gamma receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of T cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of T cell activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Lck	Homo sapiens (human)
release of sequestered calcium ion into cytosol	Tyrosine-protein kinase Lck	Homo sapiens (human)
regulation of lymphocyte activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of leukocyte cell-cell adhesion	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Lck	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
response to singlet oxygen	Tyrosine-protein kinase Fyn	Homo sapiens (human)
neuron migration	Tyrosine-protein kinase Fyn	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
heart process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
calcium ion transport	Tyrosine-protein kinase Fyn	Homo sapiens (human)
G protein-coupled glutamate receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
axon guidance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
learning	Tyrosine-protein kinase Fyn	Homo sapiens (human)
feeding behavior	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase Fyn	Homo sapiens (human)
gene expression	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of gene expression	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of hydrogen peroxide biosynthetic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein ubiquitination	Tyrosine-protein kinase Fyn	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein catabolic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
forebrain development	Tyrosine-protein kinase Fyn	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of protein ubiquitination	Tyrosine-protein kinase Fyn	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of protein catabolic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Fyn	Homo sapiens (human)
response to ethanol	Tyrosine-protein kinase Fyn	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite morphogenesis	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
activated T cell proliferation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
modulation of chemical synaptic transmission	Tyrosine-protein kinase Fyn	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Fyn	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of pain	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein targeting to membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendritic spine maintenance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein localization to nucleus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of glutamate receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of dendritic spine maintenance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
response to amyloid-beta	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to amyloid-beta	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to L-glutamate	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to glycine	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein localization to membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of calcium ion import across plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA replication	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 1	Homo sapiens (human)
chromatin remodeling	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 1	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
apoptotic process	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA damage response	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic nuclear membrane disassembly	Cyclin-dependent kinase 1	Homo sapiens (human)
centrosome cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
pronuclear fusion	Cyclin-dependent kinase 1	Homo sapiens (human)
response to xenobiotic stimulus	Cyclin-dependent kinase 1	Homo sapiens (human)
response to toxic substance	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of gene expression	Cyclin-dependent kinase 1	Homo sapiens (human)
negative regulation of gene expression	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of Schwann cell differentiation	Cyclin-dependent kinase 1	Homo sapiens (human)
response to amine	Cyclin-dependent kinase 1	Homo sapiens (human)
response to activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cell migration	Cyclin-dependent kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
chromosome condensation	Cyclin-dependent kinase 1	Homo sapiens (human)
epithelial cell differentiation	Cyclin-dependent kinase 1	Homo sapiens (human)
animal organ regeneration	Cyclin-dependent kinase 1	Homo sapiens (human)
protein localization to kinetochore	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of protein import into nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of circadian rhythm	Cyclin-dependent kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Cyclin-dependent kinase 1	Homo sapiens (human)
response to ethanol	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of DNA replication	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of embryonic development	Cyclin-dependent kinase 1	Homo sapiens (human)
response to cadmium ion	Cyclin-dependent kinase 1	Homo sapiens (human)
response to copper ion	Cyclin-dependent kinase 1	Homo sapiens (human)
symbiont entry into host cell	Cyclin-dependent kinase 1	Homo sapiens (human)
fibroblast proliferation	Cyclin-dependent kinase 1	Homo sapiens (human)
rhythmic process	Cyclin-dependent kinase 1	Homo sapiens (human)
response to axon injury	Cyclin-dependent kinase 1	Homo sapiens (human)
cell division	Cyclin-dependent kinase 1	Homo sapiens (human)
ventricular cardiac muscle cell development	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of mitotic sister chromatid segregation	Cyclin-dependent kinase 1	Homo sapiens (human)
protein-containing complex assembly	Cyclin-dependent kinase 1	Homo sapiens (human)
cellular response to hydrogen peroxide	Cyclin-dependent kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Cyclin-dependent kinase 1	Homo sapiens (human)
cellular response to organic cyclic compound	Cyclin-dependent kinase 1	Homo sapiens (human)
Golgi disassembly	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of attachment of mitotic spindle microtubules to kinetochore	Cyclin-dependent kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization involved in mitosis	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of mitochondrial ATP synthesis coupled electron transport	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Cyclin-dependent kinase 1	Homo sapiens (human)
protein deubiquitination	Cyclin-dependent kinase 1	Homo sapiens (human)
glycogen metabolic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
5-phosphoribose 1-diphosphate biosynthetic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
response to bacterium	Glycogen phosphorylase, liver form	Homo sapiens (human)
glucose homeostasis	Glycogen phosphorylase, liver form	Homo sapiens (human)
necroptotic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
glycogen catabolic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
microtubule bundle formation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
centrosome cycle	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell adhesion	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of microtubule polymerization	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell population proliferation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of mast cell degranulation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell differentiation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of myeloid cell differentiation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of monocyte differentiation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
myoblast proliferation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cardiac muscle cell proliferation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of vesicle-mediated transport	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cellular response to vitamin D	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell motility	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
chemotaxis	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of macrophage proliferation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
response to ischemia	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
inflammatory response	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
signal transduction	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
axon guidance	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cell population proliferation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
negative regulation of cell population proliferation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
regulation of cell shape	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cytokine-mediated signaling pathway	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
olfactory bulb development	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
forebrain neuron differentiation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
hemopoiesis	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
monocyte differentiation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
macrophage differentiation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
osteoclast differentiation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
ruffle organization	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of chemokine production	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
regulation of actin cytoskeleton organization	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cellular response to macrophage colony-stimulating factor stimulus	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
macrophage colony-stimulating factor signaling pathway	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
negative regulation of apoptotic process	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation by host of viral process	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
innate immune response	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
regulation of bone resorption	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cell-cell junction maintenance	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
protein autophosphorylation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
mammary gland duct morphogenesis	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of protein tyrosine kinase activity	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
microglial cell proliferation	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cellular response to cytokine stimulus	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
regulation of macrophage migration	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of cell motility	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of cell migration	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
regulation of MAPK cascade	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
positive regulation of kinase activity	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
multicellular organism development	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
response to bacterium	Carbonic anhydrase 3	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 3	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
regulation of glucose transmembrane transport	Tyrosine-protein kinase Yes	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase Yes	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Yes	Homo sapiens (human)
regulation of vascular permeability	Tyrosine-protein kinase Yes	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase Yes	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Yes	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Yes	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Yes	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Yes	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Yes	Homo sapiens (human)
DNA damage checkpoint signaling	Tyrosine-protein kinase Lyn	Homo sapiens (human)
B cell homeostasis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of cytokine production	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
tolerance induction to self antigen	Tyrosine-protein kinase Lyn	Homo sapiens (human)
histamine secretion by mast cell	Tyrosine-protein kinase Lyn	Homo sapiens (human)
platelet degranulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of myeloid leukocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
immune response-regulating cell surface receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc receptor mediated inhibitory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of B cell apoptotic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
DNA damage response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to sterol depletion	Tyrosine-protein kinase Lyn	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to toxic substance	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to hormone	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to carbohydrate	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
oligodendrocyte development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to organic cyclic compound	Tyrosine-protein kinase Lyn	Homo sapiens (human)
fatty acid transport	Tyrosine-protein kinase Lyn	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
erythrocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
eosinophil differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of B cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to insulin	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of mast cell activation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of toll-like receptor 2 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of toll-like receptor 4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cellular response to heat	Tyrosine-protein kinase Lyn	Homo sapiens (human)
interleukin-5-mediated signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
C-X-C chemokine receptor CXCR4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to amino acid	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of mast cell degranulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of MAP kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of erythrocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to axon injury	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of B cell receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of glial cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of oligodendrocyte progenitor proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of mast cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of mast cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of monocyte chemotaxis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of platelet aggregation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
dendritic cell differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of intracellular signal transduction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of dendritic cell apoptotic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
neuron projection development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
MAPK cascade	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
ureteric bud development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neural crest cell migration	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
embryonic epithelial tube formation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
homophilic cell adhesion via plasma membrane adhesion molecules	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neuron cell-cell adhesion	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
signal transduction	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
axon guidance	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
posterior midgut development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
response to xenobiotic stimulus	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of gene expression	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of neuron projection development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of neuron maturation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
regulation of cell adhesion	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of cell migration	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
membrane protein proteolysis	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of cell adhesion mediated by integrin	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
ureter maturation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
glial cell-derived neurotrophic factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neuron maturation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of MAPK cascade	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of cell size	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of DNA-templated transcription	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
response to pain	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
enteric nervous system development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
regulation of axonogenesis	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
retina development in camera-type eye	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
innervation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
Peyer's patch morphogenesis	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
cellular response to retinoic acid	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of metanephric glomerulus development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
lymphocyte migration into lymphoid organs	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
GDF15-GFRAL signaling pathway	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of kinase activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
multicellular organism development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cardiac atrium development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
immune response	Insulin-like growth factor 1 receptor	Homo sapiens (human)
signal transduction	Insulin-like growth factor 1 receptor	Homo sapiens (human)
axonogenesis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor signaling pathway	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of muscle cell apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cerebellum development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
hippocampus development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
establishment of cell polarity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cell migration	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cytokinesis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to vitamin E	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of osteoblast proliferation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to zinc ion starvation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to nicotine	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of protein-containing complex disassembly	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to alkaloid	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of MAPK cascade	Insulin-like growth factor 1 receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin-like growth factor 1 receptor	Homo sapiens (human)
estrous cycle	Insulin-like growth factor 1 receptor	Homo sapiens (human)
transcytosis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to ethanol	Insulin-like growth factor 1 receptor	Homo sapiens (human)
regulation of JNK cascade	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein autophosphorylation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of axon regeneration	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of DNA metabolic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to mechanical stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to estradiol stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to progesterone stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to testosterone stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to dexamethasone stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of steroid hormone biosynthetic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular senescence	Insulin-like growth factor 1 receptor	Homo sapiens (human)
dendritic spine maintenance	Insulin-like growth factor 1 receptor	Homo sapiens (human)
amyloid-beta clearance	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to L-glutamate	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of hepatocyte apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to aldosterone	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of cholangiocyte apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to angiotensin	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to amyloid-beta	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to insulin-like growth factor stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
multicellular organism development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of kinase activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to glucose stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cotranslational protein targeting to membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
intracellular protein transport	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
protein targeting to ER	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
mitochondrial electron transport, ubiquinol to cytochrome c	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
response to glucagon	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
cellular respiration	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
proton transmembrane transport	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
endothelial cell morphogenesis	Hepatocyte growth factor receptor	Homo sapiens (human)
signal transduction	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of autophagy	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of microtubule polymerization	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of Rho protein signal transduction	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Hepatocyte growth factor receptor	Homo sapiens (human)
hepatocyte growth factor receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
branching morphogenesis of an epithelial tube	Hepatocyte growth factor receptor	Homo sapiens (human)
positive chemotaxis	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of stress fiber assembly	Hepatocyte growth factor receptor	Homo sapiens (human)
excitatory postsynaptic potential	Hepatocyte growth factor receptor	Homo sapiens (human)
establishment of skin barrier	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of thrombin-activated receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
semaphorin-plexin signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of hydrogen peroxide-mediated programmed cell death	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of guanyl-nucleotide exchange factor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Hepatocyte growth factor receptor	Homo sapiens (human)
liver development	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
phagocytosis	Hepatocyte growth factor receptor	Homo sapiens (human)
multicellular organism development	Hepatocyte growth factor receptor	Homo sapiens (human)
neuron differentiation	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	Hepatocyte growth factor receptor	Homo sapiens (human)
cell migration	Hepatocyte growth factor receptor	Homo sapiens (human)
pancreas development	Hepatocyte growth factor receptor	Homo sapiens (human)
nervous system development	Hepatocyte growth factor receptor	Homo sapiens (human)
leukocyte migration involved in immune response	Tyrosine-protein kinase HCK	Homo sapiens (human)
innate immune response-activating signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
inflammatory response	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase HCK	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase HCK	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase HCK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
positive regulation of actin filament polymerization	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase HCK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase HCK	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
negative regulation of apoptotic process	Tyrosine-protein kinase HCK	Homo sapiens (human)
leukocyte degranulation	Tyrosine-protein kinase HCK	Homo sapiens (human)
respiratory burst after phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of inflammatory response	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of podosome assembly	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase HCK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipid hydroxylation	Cytochrome P450 3A4	Homo sapiens (human)
lipid metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
steroid catabolic process	Cytochrome P450 3A4	Homo sapiens (human)
xenobiotic metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
steroid metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
cholesterol metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
androgen metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
estrogen metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
alkaloid catabolic process	Cytochrome P450 3A4	Homo sapiens (human)
monoterpenoid metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
calcitriol biosynthetic process from calciol	Cytochrome P450 3A4	Homo sapiens (human)
xenobiotic catabolic process	Cytochrome P450 3A4	Homo sapiens (human)
vitamin D metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
vitamin D catabolic process	Cytochrome P450 3A4	Homo sapiens (human)
retinol metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
retinoic acid metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
long-chain fatty acid biosynthetic process	Cytochrome P450 3A4	Homo sapiens (human)
aflatoxin metabolic process	Cytochrome P450 3A4	Homo sapiens (human)
oxidative demethylation	Cytochrome P450 3A4	Homo sapiens (human)
regulation of cell growth	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
columnar/cuboidal epithelial cell development	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
spermatogenesis	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
cell differentiation	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
regulation of TOR signaling	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
positive regulation of kinase activity	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
multicellular organism development	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
signal transduction	Platelet-derived growth factor receptor beta	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell population proliferation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phospholipase C activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Platelet-derived growth factor receptor beta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell migration	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phosphoprotein phosphatase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
regulation of actin cytoskeleton organization	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell migration involved in vasculogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
aorta morphogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of MAP kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of mitotic nuclear division	Platelet-derived growth factor receptor beta	Homo sapiens (human)
phosphatidylinositol metabolic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein autophosphorylation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cardiac myofibril assembly	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell migration involved in coronary angiogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
retina vasculature development in camera-type eye	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Platelet-derived growth factor receptor beta	Homo sapiens (human)
smooth muscle cell chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
metanephric glomerular mesangial cell proliferation involved in metanephros development	Platelet-derived growth factor receptor beta	Homo sapiens (human)
metanephric glomerular capillary formation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of calcium ion import	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
angiogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
multicellular organism development	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cytokine production	Tyrosine-protein kinase Fgr	Homo sapiens (human)
immune response-regulating cell surface receptor signaling pathway	Tyrosine-protein kinase Fgr	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Fgr	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase Fgr	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase Fgr	Homo sapiens (human)
response to virus	Tyrosine-protein kinase Fgr	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
bone mineralization	Tyrosine-protein kinase Fgr	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase Fgr	Homo sapiens (human)
negative regulation of natural killer cell activation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Fgr	Homo sapiens (human)
positive regulation of mast cell degranulation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
regulation of innate immune response	Tyrosine-protein kinase Fgr	Homo sapiens (human)
regulation of protein kinase activity	Tyrosine-protein kinase Fgr	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
skeletal system morphogenesis	Tyrosine-protein kinase Fgr	Homo sapiens (human)
regulation of phagocytosis	Tyrosine-protein kinase Fgr	Homo sapiens (human)
defense response to Gram-positive bacterium	Tyrosine-protein kinase Fgr	Homo sapiens (human)
myoblast proliferation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase Fgr	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Fgr	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Fgr	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Fgr	Homo sapiens (human)
mitotic cell cycle	Wee1-like protein kinase 2	Homo sapiens (human)
female meiotic nuclear division	Wee1-like protein kinase 2	Homo sapiens (human)
female pronucleus assembly	Wee1-like protein kinase 2	Homo sapiens (human)
positive regulation of phosphorylation	Wee1-like protein kinase 2	Homo sapiens (human)
regulation of meiosis I	Wee1-like protein kinase 2	Homo sapiens (human)
regulation of fertilization	Wee1-like protein kinase 2	Homo sapiens (human)
negative regulation of oocyte maturation	Wee1-like protein kinase 2	Homo sapiens (human)
protein phosphorylation	Wee1-like protein kinase 2	Homo sapiens (human)
regulation of TOR signaling	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
regulation of proteasomal ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein modification process	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
ovarian follicle development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
myeloid progenitor cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
lymphoid progenitor cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
immature B cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell chemotaxis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of dendritic cell cytokine production	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
glycosphingolipid metabolic process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
inflammatory response	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
signal transduction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
spermatogenesis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
spermatid development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
germ cell migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
regulation of cell shape	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
visual learning	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
male gonad development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of phospholipase C activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cytokine-mediated signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
stem cell population maintenance	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
lamellipodium assembly	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
actin cytoskeleton organization	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
hemopoiesis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
T cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
erythrocyte differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
melanocyte differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of pseudopodium assembly	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of mast cell cytokine production	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
somatic stem cell population maintenance	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
embryonic hemopoiesis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
ectopic germ cell programmed cell death	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
intracellular signal transduction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
hematopoietic stem cell migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
megakaryocyte development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
Fc receptor signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
Kit signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
erythropoietin-mediated signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
regulation of cell population proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
negative regulation of programmed cell death	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell degranulation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of MAPK cascade	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
pigmentation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
tongue development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of Notch signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
response to cadmium ion	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein autophosphorylation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of long-term neuronal synaptic plasticity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
digestive tract development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
stem cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
epithelial cell proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of sound	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
negative regulation of developmental process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cell chemotaxis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of mast cell proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
melanocyte migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
melanocyte adhesion	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of pyloric antrum smooth muscle contraction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
regulation of bile acid metabolic process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of colon smooth muscle contraction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of small intestine smooth muscle contraction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
negative regulation of reproductive process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of cell migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of MAP kinase activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
multicellular organism development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
B cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
glycogen catabolic process	Glycogen phosphorylase, brain form	Homo sapiens (human)
negative regulation of cellular extravasation	Breakpoint cluster region protein	Homo sapiens (human)
renal system process	Breakpoint cluster region protein	Homo sapiens (human)
protein phosphorylation	Breakpoint cluster region protein	Homo sapiens (human)
phagocytosis	Breakpoint cluster region protein	Homo sapiens (human)
signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
small GTPase-mediated signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
brain development	Breakpoint cluster region protein	Homo sapiens (human)
actin cytoskeleton organization	Breakpoint cluster region protein	Homo sapiens (human)
keratinocyte differentiation	Breakpoint cluster region protein	Homo sapiens (human)
regulation of Rho protein signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
inner ear morphogenesis	Breakpoint cluster region protein	Homo sapiens (human)
regulation of vascular permeability	Breakpoint cluster region protein	Homo sapiens (human)
neutrophil degranulation	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of neutrophil degranulation	Breakpoint cluster region protein	Homo sapiens (human)
focal adhesion assembly	Breakpoint cluster region protein	Homo sapiens (human)
homeostasis of number of cells	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of inflammatory response	Breakpoint cluster region protein	Homo sapiens (human)
positive regulation of phagocytosis	Breakpoint cluster region protein	Homo sapiens (human)
modulation of chemical synaptic transmission	Breakpoint cluster region protein	Homo sapiens (human)
neuromuscular process controlling balance	Breakpoint cluster region protein	Homo sapiens (human)
regulation of small GTPase mediated signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
regulation of cell cycle	Breakpoint cluster region protein	Homo sapiens (human)
definitive hemopoiesis	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of respiratory burst	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of blood vessel remodeling	Breakpoint cluster region protein	Homo sapiens (human)
intracellular protein transmembrane transport	Breakpoint cluster region protein	Homo sapiens (human)
cellular response to lipopolysaccharide	Breakpoint cluster region protein	Homo sapiens (human)
activation of GTPase activity	Breakpoint cluster region protein	Homo sapiens (human)
macrophage migration	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of macrophage migration	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of reactive oxygen species metabolic process	Breakpoint cluster region protein	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
regulation of transmembrane transporter activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
negative regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
negative regulation of innate immune response	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
vitamin D receptor signaling pathway	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cellular response to type II interferon	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of brown fat cell differentiation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
regulation of hematopoietic stem cell proliferation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of TORC1 signaling	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of cardioblast proliferation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cellular detoxification	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Fibroblast growth factor receptor 1	Homo sapiens (human)
MAPK cascade	Fibroblast growth factor receptor 1	Homo sapiens (human)
skeletal system development	Fibroblast growth factor receptor 1	Homo sapiens (human)
angiogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
ureteric bud development	Fibroblast growth factor receptor 1	Homo sapiens (human)
in utero embryonic development	Fibroblast growth factor receptor 1	Homo sapiens (human)
organ induction	Fibroblast growth factor receptor 1	Homo sapiens (human)
neuron migration	Fibroblast growth factor receptor 1	Homo sapiens (human)
epithelial to mesenchymal transition	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
chondrocyte differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein phosphorylation	Fibroblast growth factor receptor 1	Homo sapiens (human)
sensory perception of sound	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
mesenchymal cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
gene expression	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of phospholipase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of phospholipase C activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of phosphate transport	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of neuron projection development	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell migration	Fibroblast growth factor receptor 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Fibroblast growth factor receptor 1	Homo sapiens (human)
ventricular zone neuroblast division	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell projection assembly	Fibroblast growth factor receptor 1	Homo sapiens (human)
embryonic limb morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
midbrain development	Fibroblast growth factor receptor 1	Homo sapiens (human)
neuron projection development	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	Fibroblast growth factor receptor 1	Homo sapiens (human)
inner ear morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
outer ear morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
middle ear morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
chordate embryonic development	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of MAP kinase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of MAPK cascade	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Fibroblast growth factor receptor 1	Homo sapiens (human)
cellular response to fibroblast growth factor stimulus	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of cell differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of neuron differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein autophosphorylation	Fibroblast growth factor receptor 1	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Fibroblast growth factor receptor 1	Homo sapiens (human)
paraxial mesoderm development	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of lateral mesodermal cell fate specification	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell maturation	Fibroblast growth factor receptor 1	Homo sapiens (human)
skeletal system morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
stem cell differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Fibroblast growth factor receptor 1	Homo sapiens (human)
calcium ion homeostasis	Fibroblast growth factor receptor 1	Homo sapiens (human)
cardiac muscle cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
auditory receptor cell development	Fibroblast growth factor receptor 1	Homo sapiens (human)
branching involved in salivary gland morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
lung-associated mesenchyme development	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Fibroblast growth factor receptor 1	Homo sapiens (human)
vitamin D3 metabolic process	Fibroblast growth factor receptor 1	Homo sapiens (human)
diphosphate metabolic process	Fibroblast growth factor receptor 1	Homo sapiens (human)
cementum mineralization	Fibroblast growth factor receptor 1	Homo sapiens (human)
stem cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
negative regulation of fibroblast growth factor production	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of mitotic cell cycle DNA replication	Fibroblast growth factor receptor 1	Homo sapiens (human)
response to sodium phosphate	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of vascular endothelial cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of stem cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of parathyroid hormone secretion	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of extrinsic apoptotic signaling pathway in absence of ligand	Fibroblast growth factor receptor 1	Homo sapiens (human)
multicellular organism development	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of cell differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
hematopoietic progenitor cell differentiation	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA topological change	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA ligation	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA damage response	DNA topoisomerase 2-alpha	Homo sapiens (human)
chromosome segregation	DNA topoisomerase 2-alpha	Homo sapiens (human)
female meiotic nuclear division	DNA topoisomerase 2-alpha	Homo sapiens (human)
apoptotic chromosome condensation	DNA topoisomerase 2-alpha	Homo sapiens (human)
embryonic cleavage	DNA topoisomerase 2-alpha	Homo sapiens (human)
regulation of circadian rhythm	DNA topoisomerase 2-alpha	Homo sapiens (human)
positive regulation of apoptotic process	DNA topoisomerase 2-alpha	Homo sapiens (human)
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	DNA topoisomerase 2-alpha	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	DNA topoisomerase 2-alpha	Homo sapiens (human)
rhythmic process	DNA topoisomerase 2-alpha	Homo sapiens (human)
negative regulation of DNA duplex unwinding	DNA topoisomerase 2-alpha	Homo sapiens (human)
resolution of meiotic recombination intermediates	DNA topoisomerase 2-alpha	Homo sapiens (human)
sister chromatid segregation	DNA topoisomerase 2-alpha	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 4	Homo sapiens (human)
positive regulation of cell population proliferation	Cyclin-dependent kinase 4	Homo sapiens (human)
response to xenobiotic stimulus	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 4	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
positive regulation of fibroblast proliferation	Cyclin-dependent kinase 4	Homo sapiens (human)
cell division	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of transcription initiation by RNA polymerase II	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of type B pancreatic cell proliferation	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to lipopolysaccharide	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to interleukin-4	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to phorbol 13-acetate 12-myristate	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to ionomycin	Cyclin-dependent kinase 4	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 4	Homo sapiens (human)
apoptotic process	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrial ADP transmembrane transport	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrial ATP transmembrane transport	ADP/ATP translocase 3	Homo sapiens (human)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ADP/ATP translocase 3	Homo sapiens (human)
GMP biosynthetic process	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
GTP biosynthetic process	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
circadian rhythm	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
lymphocyte proliferation	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cellular response to interleukin-4	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
'de novo' XMP biosynthetic process	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
primary ovarian follicle growth	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of cytokine production	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signal complex assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
integrin-mediated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
spermatogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
learning or memory	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to xenobiotic stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to mechanical stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to acidic pH	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of gene expression	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of epithelial cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of epithelial cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of glucose metabolic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein processing	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
skeletal muscle cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
macroautophagy	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of cell-cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
platelet activation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
forebrain development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
T cell costimulation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein destabilization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to nutrient levels	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of telomere maintenance via telomerase	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to insulin stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of intracellular estrogen receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of integrin activation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of toll-like receptor 3 signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
adherens junction organization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of dephosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of hippo signaling	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
intracellular signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
entry of bacterium into host cell	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
osteoclast development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ERBB2 signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
angiotensin-activated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
odontogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of vascular permeability	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
stress fiber assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transcytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of Notch signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of Ras protein signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein autophosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
neurotrophin TRK receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ephrin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
focal adhesion assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
oogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
progesterone receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
leukocyte migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of small GTPase mediated signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein transport	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to mineralocorticoid	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
myoblast proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to electrical stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of focal adhesion assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of mitochondrial depolarization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of telomerase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
uterus development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of cell projection assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
intestinal epithelial cell development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to hydrogen peroxide	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to interleukin-1	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to lipopolysaccharide	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to peptide hormone stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to progesterone stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to fatty acid	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to hypoxia	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to fluid shear stress	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of podosome assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
DNA biosynthetic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell-cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein localization to nucleus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of TORC1 signaling	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to prolactin	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of male germ cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of ovarian follicle development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of lamellipodium morphogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of platelet-derived growth factor receptor-beta signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of early endosome to late endosome transport	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of anoikis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of caveolin-mediated endocytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell differentiation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
innate immune response	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
symbiont entry into host cell	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of protein phosphorylation	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
intracellular signal transduction	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
negative regulation of cAMP/PKA signal transduction	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
negative regulation of cAMP-dependent protein kinase activity	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Insulin receptor-related protein	Homo sapiens (human)
insulin receptor signaling pathway	Insulin receptor-related protein	Homo sapiens (human)
actin cytoskeleton organization	Insulin receptor-related protein	Homo sapiens (human)
male sex determination	Insulin receptor-related protein	Homo sapiens (human)
protein autophosphorylation	Insulin receptor-related protein	Homo sapiens (human)
cellular response to alkaline pH	Insulin receptor-related protein	Homo sapiens (human)
positive regulation of kinase activity	Insulin receptor-related protein	Homo sapiens (human)
multicellular organism development	Insulin receptor-related protein	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
myeloid progenitor cell differentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
visual learning	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
animal organ morphogenesis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of gene expression	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of fibroblast migration	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of glucose transmembrane transport	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
synaptic vesicle exocytosis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
thyroid gland development	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
T cell differentiation in thymus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
somatic stem cell population maintenance	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
regulation of cell population proliferation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
stress fiber assembly	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
CD4-positive, alpha-beta T cell differentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
response to peptide hormone	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of neuron apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
regulation of T cell differentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
thymus development	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of axon regeneration	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of axonogenesis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
T cell receptor signaling pathway	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of stress fiber assembly	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
response to cAMP	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
long-term synaptic potentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
head morphogenesis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
face development	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
ERK1 and ERK2 cascade	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cellular response to calcium ion	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cellular response to xenobiotic stimulus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
endothelial cell apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
establishment of protein localization to membrane	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cellular response to nerve growth factor stimulus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of synaptic vesicle exocytosis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
epithelial cell maturation	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
sensory perception of sound	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
male gonad development	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
vestibular nucleus development	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
secretory granule organization	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane repolarization	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cellular response to cAMP	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cellular response to acidic pH	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cellular response to light stimulus	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
potassium ion transmembrane transport	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cardiac muscle cell action potential involved in contraction	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cardiac muscle cell contraction	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
membrane repolarization	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
membrane repolarization during action potential	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
membrane repolarization during cardiac muscle cell action potential	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
negative regulation of protein targeting to membrane	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
membrane repolarization during ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
positive regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
regulation of delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
negative regulation of delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
glycogen metabolic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
glycogen biosynthetic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
glycogen catabolic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
generation of precursor metabolites and energy	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
protein phosphorylation	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
positive regulation of glycogen catabolic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
quinone catabolic process	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
cellular response to reactive oxygen species	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
luteinization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
in utero embryonic development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell activation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
estrogen metabolic process	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell population proliferation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
negative regulation of platelet activation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of phospholipase C activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
signal transduction involved in regulation of gene expression	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
extracellular matrix organization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
lung development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
adrenal gland development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell migration	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
male genitalia development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
regulation of actin cytoskeleton organization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
Leydig cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor-alpha signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
wound healing	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein autophosphorylation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of fibroblast proliferation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic digestive tract morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic skeletal system morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
white fat cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of chemotaxis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cardiac myofibril assembly	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
roof of mouth development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
face morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell chemotaxis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
retina vasculature development in camera-type eye	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet aggregation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cellular response to amino acid stimulus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
metanephric glomerular capillary formation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
regulation of mesenchymal stem cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
multicellular organism development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
microtubule cytoskeleton organization	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of protein phosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Fer	Homo sapiens (human)
germ cell development	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase Fer	Homo sapiens (human)
insulin receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of lamellipodium assembly	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of fibroblast migration	Tyrosine-protein kinase Fer	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
actin cytoskeleton organization	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of actin filament polymerization	Tyrosine-protein kinase Fer	Homo sapiens (human)
response to lipopolysaccharide	Tyrosine-protein kinase Fer	Homo sapiens (human)
negative regulation of mast cell activation involved in immune response	Tyrosine-protein kinase Fer	Homo sapiens (human)
adherens junction assembly	Tyrosine-protein kinase Fer	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase Fer	Homo sapiens (human)
cellular response to reactive oxygen species	Tyrosine-protein kinase Fer	Homo sapiens (human)
extracellular matrix-cell signaling	Tyrosine-protein kinase Fer	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Fer	Homo sapiens (human)
cellular response to macrophage colony-stimulating factor stimulus	Tyrosine-protein kinase Fer	Homo sapiens (human)
response to platelet-derived growth factor	Tyrosine-protein kinase Fer	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
Kit signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of epidermal growth factor receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell-cell adhesion mediated by cadherin	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
diapedesis	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase Fer	Homo sapiens (human)
Sertoli cell development	Tyrosine-protein kinase Fer	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
seminiferous tubule development	Tyrosine-protein kinase Fer	Homo sapiens (human)
adherens junction disassembly	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase Fer	Homo sapiens (human)
chemotaxis	Tyrosine-protein kinase Fer	Homo sapiens (human)
angiogenesis	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Protein kinase C alpha type	Homo sapiens (human)
desmosome assembly	Protein kinase C alpha type	Homo sapiens (human)
chromatin remodeling	Protein kinase C alpha type	Homo sapiens (human)
protein phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
mitotic nuclear membrane disassembly	Protein kinase C alpha type	Homo sapiens (human)
cell adhesion	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of endothelial cell migration	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Protein kinase C alpha type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cell migration	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of lipopolysaccharide-mediated signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C alpha type	Homo sapiens (human)
regulation of mRNA stability	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Protein kinase C alpha type	Homo sapiens (human)
post-translational protein modification	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of macrophage differentiation	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of angiogenesis	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of bone resorption	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cell adhesion	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of mitotic cell cycle	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein kinase C alpha type	Homo sapiens (human)
response to interleukin-1	Protein kinase C alpha type	Homo sapiens (human)
regulation of platelet aggregation	Protein kinase C alpha type	Homo sapiens (human)
apoptotic signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of angiotensin-activated signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of dense core granule biogenesis	Protein kinase C alpha type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C alpha type	Homo sapiens (human)
mesoderm formation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
neural tube closure	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of heart rate	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
renal water homeostasis	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
mRNA processing	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein phosphorylation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein export from nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathway	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of macroautophagy	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytokine-mediated signaling pathway	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of insulin secretion	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of interleukin-2 production	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
high-density lipoprotein particle assembly	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to heat	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
mitochondrial protein catabolic process	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of osteoblast differentiation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of gluconeogenesis	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of smoothened signaling pathway	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of protein export from nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
sperm capacitation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of calcium-mediated signaling	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cell cycle	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cardiac muscle contraction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of proteasomal protein catabolic process	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to cold	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of protein processing	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to glucose stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to parathyroid hormone stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to glucagon stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to epinephrine stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cell communication by electrical coupling involved in cardiac conduction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
postsynaptic modulation of chemical synaptic transmission	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cardiac conduction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of TORC1 signaling	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of glycolytic process through fructose-6-phosphate	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein localization to lipid droplet	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of bicellular tight junction assembly	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
monocyte chemotaxis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of phospholipase C activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cell migration	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cell differentiation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor receptor-1 signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of MAP kinase activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of angiogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
blood vessel morphogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
embryonic morphogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
negative regulation of vascular endothelial cell proliferation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
hyaloid vascular plexus regression	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
response to hypoxia	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
in utero embryonic development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription-coupled nucleotide-excision repair	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
nucleotide-excision repair	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
regulation of transcription by RNA polymerase II	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription elongation by RNA polymerase I	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription by RNA polymerase II	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription initiation at RNA polymerase II promoter	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
apoptotic process	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
response to oxidative stress	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
chromosome segregation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
determination of adult lifespan	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
UV protection	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
post-embryonic development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
spinal cord development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
extracellular matrix organization	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
bone mineralization	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
central nervous system myelin formation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
DNA duplex unwinding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
multicellular organism growth	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hair cell differentiation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
embryonic cleavage	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
erythrocyte maturation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
embryonic organ development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hair follicle maturation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hematopoietic stem cell differentiation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hematopoietic stem cell proliferation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediator	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
regulation of mitotic cell cycle phase transition	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
positive regulation of mitotic recombination	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
positive regulation of cytokine production	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
translation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein phosphorylation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
negative regulation of cell population proliferation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
response to virus	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
negative regulation of translation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
endoplasmic reticulum unfolded protein response	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
positive regulation of chemokine production	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
negative regulation of osteoblast proliferation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
cellular response to amino acid starvation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
response to interferon-alpha	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
negative regulation of apoptotic process	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
positive regulation of MAPK cascade	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
negative regulation of viral genome replication	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein autophosphorylation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
defense response to virus	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
antiviral innate immune response	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
regulation of NLRP3 inflammasome complex assembly	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
regulation of hematopoietic progenitor cell differentiation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
regulation of hematopoietic stem cell proliferation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
regulation of hematopoietic stem cell differentiation	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
eiF2alpha phosphorylation in response to endoplasmic reticulum stress	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
double-strand break repair	Casein kinase II subunit alpha'	Homo sapiens (human)
apoptotic process	Casein kinase II subunit alpha'	Homo sapiens (human)
spermatogenesis	Casein kinase II subunit alpha'	Homo sapiens (human)
Wnt signaling pathway	Casein kinase II subunit alpha'	Homo sapiens (human)
cerebral cortex development	Casein kinase II subunit alpha'	Homo sapiens (human)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase II subunit alpha'	Homo sapiens (human)
liver regeneration	Casein kinase II subunit alpha'	Homo sapiens (human)
regulation of mitophagy	Casein kinase II subunit alpha'	Homo sapiens (human)
positive regulation of protein targeting to mitochondrion	Casein kinase II subunit alpha'	Homo sapiens (human)
regulation of chromosome separation	Casein kinase II subunit alpha'	Homo sapiens (human)
negative regulation of apoptotic signaling pathway	Casein kinase II subunit alpha'	Homo sapiens (human)
peptidyl-threonine phosphorylation	Casein kinase II subunit alpha'	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase II subunit alpha'	Homo sapiens (human)
peptidyl-cysteine methylation	Ras-related protein Rab-6A	Homo sapiens (human)
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	Ras-related protein Rab-6A	Homo sapiens (human)
antigen processing and presentation	Ras-related protein Rab-6A	Homo sapiens (human)
neuron projection development	Ras-related protein Rab-6A	Homo sapiens (human)
protein localization to Golgi apparatus	Ras-related protein Rab-6A	Homo sapiens (human)
early endosome to Golgi transport	Ras-related protein Rab-6A	Homo sapiens (human)
minus-end-directed organelle transport along microtubule	Ras-related protein Rab-6A	Homo sapiens (human)
protein localization to Golgi membrane	Ras-related protein Rab-6A	Homo sapiens (human)
intracellular protein transport	Ras-related protein Rab-6A	Homo sapiens (human)
intra-Golgi vesicle-mediated transport	Ras-related protein Rab-6A	Homo sapiens (human)
retrograde transport, endosome to Golgi	Ras-related protein Rab-6A	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MAK	Homo sapiens (human)
spermatogenesis	Serine/threonine-protein kinase MAK	Homo sapiens (human)
cell differentiation	Serine/threonine-protein kinase MAK	Homo sapiens (human)
photoreceptor cell maintenance	Serine/threonine-protein kinase MAK	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase MAK	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase MAK	Homo sapiens (human)
negative regulation of non-motile cilium assembly	Serine/threonine-protein kinase MAK	Homo sapiens (human)
non-motile cilium assembly	Serine/threonine-protein kinase MAK	Homo sapiens (human)
intraciliary transport	Serine/threonine-protein kinase MAK	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase MAK	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase MAK	Homo sapiens (human)
mitotic cell cycle	Cyclin-dependent kinase 11B	Homo sapiens (human)
regulation of cell growth	Cyclin-dependent kinase 11B	Homo sapiens (human)
regulation of DNA-templated transcription	Cyclin-dependent kinase 11B	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 11B	Homo sapiens (human)
apoptotic process	Cyclin-dependent kinase 11B	Homo sapiens (human)
regulation of mRNA processing	Cyclin-dependent kinase 11B	Homo sapiens (human)
regulation of mitotic cell cycle	Cyclin-dependent kinase 11B	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Ephrin type-A receptor 1	Homo sapiens (human)
negative regulation of protein kinase activity	Ephrin type-A receptor 1	Homo sapiens (human)
cell surface receptor signaling pathway	Ephrin type-A receptor 1	Homo sapiens (human)
positive regulation of cell population proliferation	Ephrin type-A receptor 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Ephrin type-A receptor 1	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-A receptor 1	Homo sapiens (human)
negative regulation of cell migration	Ephrin type-A receptor 1	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Ephrin type-A receptor 1	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-A receptor 1	Homo sapiens (human)
positive regulation of angiogenesis	Ephrin type-A receptor 1	Homo sapiens (human)
protein autophosphorylation	Ephrin type-A receptor 1	Homo sapiens (human)
positive regulation of stress fiber assembly	Ephrin type-A receptor 1	Homo sapiens (human)
activation of GTPase activity	Ephrin type-A receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Ephrin type-A receptor 1	Homo sapiens (human)
multicellular organism development	Ephrin type-A receptor 1	Homo sapiens (human)
angiogenesis	Ephrin type-A receptor 1	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 1	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 2	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Fibroblast growth factor receptor 2	Homo sapiens (human)
angiogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
ureteric bud development	Fibroblast growth factor receptor 2	Homo sapiens (human)
in utero embryonic development	Fibroblast growth factor receptor 2	Homo sapiens (human)
epithelial to mesenchymal transition	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
outflow tract septum morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
membranous septum morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
endochondral bone growth	Fibroblast growth factor receptor 2	Homo sapiens (human)
apoptotic process	Fibroblast growth factor receptor 2	Homo sapiens (human)
cell-cell signaling	Fibroblast growth factor receptor 2	Homo sapiens (human)
axonogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 2	Homo sapiens (human)
regulation of smoothened signaling pathway	Fibroblast growth factor receptor 2	Homo sapiens (human)
post-embryonic development	Fibroblast growth factor receptor 2	Homo sapiens (human)
embryonic pattern specification	Fibroblast growth factor receptor 2	Homo sapiens (human)
animal organ morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of phospholipase activity	Fibroblast growth factor receptor 2	Homo sapiens (human)
negative regulation of keratinocyte proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
morphogenesis of embryonic epithelium	Fibroblast growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Fibroblast growth factor receptor 2	Homo sapiens (human)
orbitofrontal cortex development	Fibroblast growth factor receptor 2	Homo sapiens (human)
ventricular zone neuroblast division	Fibroblast growth factor receptor 2	Homo sapiens (human)
pyramidal neuron development	Fibroblast growth factor receptor 2	Homo sapiens (human)
gland morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of Wnt signaling pathway	Fibroblast growth factor receptor 2	Homo sapiens (human)
bone mineralization	Fibroblast growth factor receptor 2	Homo sapiens (human)
lung development	Fibroblast growth factor receptor 2	Homo sapiens (human)
epithelial cell differentiation	Fibroblast growth factor receptor 2	Homo sapiens (human)
midbrain development	Fibroblast growth factor receptor 2	Homo sapiens (human)
otic vesicle formation	Fibroblast growth factor receptor 2	Homo sapiens (human)
hair follicle morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
response to lipopolysaccharide	Fibroblast growth factor receptor 2	Homo sapiens (human)
lacrimal gland development	Fibroblast growth factor receptor 2	Homo sapiens (human)
regulation of osteoblast proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
organ growth	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in hemopoiesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	Fibroblast growth factor receptor 2	Homo sapiens (human)
inner ear morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
odontogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of MAPK cascade	Fibroblast growth factor receptor 2	Homo sapiens (human)
cell fate commitment	Fibroblast growth factor receptor 2	Homo sapiens (human)
response to ethanol	Fibroblast growth factor receptor 2	Homo sapiens (human)
regulation of osteoblast differentiation	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of cell cycle	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Fibroblast growth factor receptor 2	Homo sapiens (human)
protein autophosphorylation	Fibroblast growth factor receptor 2	Homo sapiens (human)
lung alveolus development	Fibroblast growth factor receptor 2	Homo sapiens (human)
mesodermal cell differentiation	Fibroblast growth factor receptor 2	Homo sapiens (human)
embryonic digestive tract morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
embryonic organ morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
digestive tract development	Fibroblast growth factor receptor 2	Homo sapiens (human)
embryonic organ development	Fibroblast growth factor receptor 2	Homo sapiens (human)
reproductive structure development	Fibroblast growth factor receptor 2	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
skeletal system morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
epidermis morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
branching morphogenesis of a nerve	Fibroblast growth factor receptor 2	Homo sapiens (human)
mesenchymal cell differentiation	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
regulation of smooth muscle cell differentiation	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of cell division	Fibroblast growth factor receptor 2	Homo sapiens (human)
ventricular cardiac muscle tissue morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
limb bud formation	Fibroblast growth factor receptor 2	Homo sapiens (human)
bone development	Fibroblast growth factor receptor 2	Homo sapiens (human)
bone morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
branching involved in prostate gland morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
branching involved in salivary gland morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
bud elongation involved in lung branching	Fibroblast growth factor receptor 2	Homo sapiens (human)
lung lobe morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
lung-associated mesenchyme development	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of epithelial cell proliferation involved in lung morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
prostate gland morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
prostate epithelial cord elongation	Fibroblast growth factor receptor 2	Homo sapiens (human)
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in mammary gland specification	Fibroblast growth factor receptor 2	Homo sapiens (human)
lateral sprouting from an epithelium	Fibroblast growth factor receptor 2	Homo sapiens (human)
mammary gland bud formation	Fibroblast growth factor receptor 2	Homo sapiens (human)
epithelial cell proliferation involved in salivary gland morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
branch elongation involved in salivary gland morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
branching involved in labyrinthine layer morphogenesis	Fibroblast growth factor receptor 2	Homo sapiens (human)
regulation of morphogenesis of a branching structure	Fibroblast growth factor receptor 2	Homo sapiens (human)
mesenchymal cell differentiation involved in lung development	Fibroblast growth factor receptor 2	Homo sapiens (human)
mesenchymal cell proliferation involved in lung development	Fibroblast growth factor receptor 2	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Fibroblast growth factor receptor 2	Homo sapiens (human)
cellular response to retinoic acid	Fibroblast growth factor receptor 2	Homo sapiens (human)
cellular response to hypoxia	Fibroblast growth factor receptor 2	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Fibroblast growth factor receptor 2	Homo sapiens (human)
multicellular organism development	Fibroblast growth factor receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Fibroblast growth factor receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Fibroblast growth factor receptor 2	Homo sapiens (human)
endocardial cushion development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
negative regulation of cell adhesion	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
signal transduction	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
peripheral nervous system development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
heart development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
negative regulation of signal transduction	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
positive regulation of gene expression	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
Schwann cell differentiation	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
Schwann cell development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
cranial nerve development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
wound healing	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
regulation of cell population proliferation	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
myelination	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
negative regulation of neuron apoptotic process	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
negative regulation of secretion	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
neuron apoptotic process	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
positive regulation of cardiac muscle tissue development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
positive regulation of calcineurin-NFAT signaling cascade	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
motor neuron apoptotic process	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligand	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
negative regulation of motor neuron apoptotic process	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
negative regulation of apoptotic process	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
neurogenesis	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
positive regulation of cell population proliferation	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
positive regulation of kinase activity	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
multicellular organism development	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
GMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
'de novo' IMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
purine nucleobase biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
'de novo' AMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
'de novo' XMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
response to bile acid	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 4	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 4	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of gene expression	Fibroblast growth factor receptor 4	Homo sapiens (human)
regulation of extracellular matrix disassembly	Fibroblast growth factor receptor 4	Homo sapiens (human)
cell migration	Fibroblast growth factor receptor 4	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Fibroblast growth factor receptor 4	Homo sapiens (human)
regulation of lipid metabolic process	Fibroblast growth factor receptor 4	Homo sapiens (human)
glucose homeostasis	Fibroblast growth factor receptor 4	Homo sapiens (human)
cholesterol homeostasis	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of catalytic activity	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of proteolysis	Fibroblast growth factor receptor 4	Homo sapiens (human)
protein autophosphorylation	Fibroblast growth factor receptor 4	Homo sapiens (human)
phosphate ion homeostasis	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Fibroblast growth factor receptor 4	Homo sapiens (human)
regulation of bile acid biosynthetic process	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Fibroblast growth factor receptor 4	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Fibroblast growth factor receptor 4	Homo sapiens (human)
multicellular organism development	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of kinase activity	Fibroblast growth factor receptor 4	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 3	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 3	Homo sapiens (human)
MAPK cascade	Fibroblast growth factor receptor 3	Homo sapiens (human)
skeletal system development	Fibroblast growth factor receptor 3	Homo sapiens (human)
endochondral ossification	Fibroblast growth factor receptor 3	Homo sapiens (human)
chondrocyte differentiation	Fibroblast growth factor receptor 3	Homo sapiens (human)
endochondral bone growth	Fibroblast growth factor receptor 3	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Fibroblast growth factor receptor 3	Homo sapiens (human)
cell-cell signaling	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 3	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of phospholipase activity	Fibroblast growth factor receptor 3	Homo sapiens (human)
bone mineralization	Fibroblast growth factor receptor 3	Homo sapiens (human)
chondrocyte proliferation	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of MAPK cascade	Fibroblast growth factor receptor 3	Homo sapiens (human)
negative regulation of developmental growth	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Fibroblast growth factor receptor 3	Homo sapiens (human)
bone morphogenesis	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Fibroblast growth factor receptor 3	Homo sapiens (human)
bone maturation	Fibroblast growth factor receptor 3	Homo sapiens (human)
fibroblast growth factor receptor apoptotic signaling pathway	Fibroblast growth factor receptor 3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Fibroblast growth factor receptor 3	Homo sapiens (human)
multicellular organism development	Fibroblast growth factor receptor 3	Homo sapiens (human)
positive regulation of kinase activity	Fibroblast growth factor receptor 3	Homo sapiens (human)
renal water homeostasis	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
spermatogenesis	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
male gonad development	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
high-density lipoprotein particle assembly	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
neural tube closure	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
renal water homeostasis	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein phosphorylation	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
signal transduction	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
high-density lipoprotein particle assembly	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
negative regulation of smoothened signaling pathway	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
regulation of protein processing	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
negative regulation of TORC1 signaling	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
bicarbonate transport	Carbonic anhydrase 4	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 4	Homo sapiens (human)
generation of precursor metabolites and energy	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme A biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme B biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
cholesterol metabolic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to xenobiotic stimulus	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to light stimulus	Ferrochelatase, mitochondrial	Homo sapiens (human)
detection of UV	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to lead ion	Ferrochelatase, mitochondrial	Homo sapiens (human)
regulation of eIF2 alpha phosphorylation by heme	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to insecticide	Ferrochelatase, mitochondrial	Homo sapiens (human)
erythrocyte differentiation	Ferrochelatase, mitochondrial	Homo sapiens (human)
very-low-density lipoprotein particle assembly	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to ethanol	Ferrochelatase, mitochondrial	Homo sapiens (human)
protoporphyrinogen IX metabolic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to arsenic-containing substance	Ferrochelatase, mitochondrial	Homo sapiens (human)
regulation of hemoglobin biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme O biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to methylmercury	Ferrochelatase, mitochondrial	Homo sapiens (human)
multicellular organismal-level iron ion homeostasis	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to platinum ion	Ferrochelatase, mitochondrial	Homo sapiens (human)
cellular response to dexamethasone stimulus	Ferrochelatase, mitochondrial	Homo sapiens (human)
detection of chemical stimulus involved in sensory perception of bitter taste	Carbonic anhydrase 6	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 6	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
behavioral fear response	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
skeletal muscle contraction	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
apoptotic process	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
germ cell development	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
long-term memory	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to xenobiotic stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to mechanical stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to toxic substance	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to glucose	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
skeletal muscle atrophy	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to electrical stimulus involved in regulation of muscle adaptation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cell migration	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to nutrient levels	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to nutrient	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
TOR signaling	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to lipopolysaccharide	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to testosterone	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to glucagon	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to tumor necrosis factor	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
negative regulation of apoptotic process	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to L-leucine	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
long-chain fatty acid import into cell	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to ethanol	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of translation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of mitotic cell cycle	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of translational initiation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
regulation of glucose import	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of skeletal muscle tissue growth	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
modulation of chemical synaptic transmission	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to type II interferon	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to growth factor stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to dexamethasone stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of TORC1 signaling	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to insulin stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to antibiotic	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
positive regulation of homotypic cell-cell adhesion	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-15-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-4-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-2-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-9-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-11-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
type III interferon-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
type I interferon-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
T-helper 17 cell lineage commitment	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cellular response to virus	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-10-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein localization to cell-cell junction	Tyrosine-protein kinase JAK1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Tyrosine-protein kinase JAK1	Homo sapiens (human)
positive regulation of sprouting angiogenesis	Tyrosine-protein kinase JAK1	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase JAK1	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase JAK1	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein phosphorylation	Protein kinase C eta type	Homo sapiens (human)
signal transduction	Protein kinase C eta type	Homo sapiens (human)
positive regulation of macrophage derived foam cell differentiation	Protein kinase C eta type	Homo sapiens (human)
cell differentiation	Protein kinase C eta type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C eta type	Homo sapiens (human)
positive regulation of keratinocyte differentiation	Protein kinase C eta type	Homo sapiens (human)
positive regulation of B cell receptor signaling pathway	Protein kinase C eta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C eta type	Homo sapiens (human)
positive regulation of glial cell proliferation	Protein kinase C eta type	Homo sapiens (human)
protein kinase C signaling	Protein kinase C eta type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C eta type	Homo sapiens (human)
regulation of bicellular tight junction assembly	Protein kinase C eta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C eta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C eta type	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 2	Homo sapiens (human)
DNA replication	Cyclin-dependent kinase 2	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 2	Homo sapiens (human)
chromatin remodeling	Cyclin-dependent kinase 2	Homo sapiens (human)
DNA-templated transcription	Cyclin-dependent kinase 2	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 2	Homo sapiens (human)
potassium ion transport	Cyclin-dependent kinase 2	Homo sapiens (human)
centriole replication	Cyclin-dependent kinase 2	Homo sapiens (human)
Ras protein signal transduction	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of cell population proliferation	Cyclin-dependent kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of heterochromatin formation	Cyclin-dependent kinase 2	Homo sapiens (human)
mitotic G1 DNA damage checkpoint signaling	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of DNA-templated DNA replication initiation	Cyclin-dependent kinase 2	Homo sapiens (human)
telomere maintenance in response to DNA damage	Cyclin-dependent kinase 2	Homo sapiens (human)
post-translational protein modification	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of DNA replication	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Cyclin-dependent kinase 2	Homo sapiens (human)
centrosome duplication	Cyclin-dependent kinase 2	Homo sapiens (human)
cell division	Cyclin-dependent kinase 2	Homo sapiens (human)
meiotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
cellular response to nitric oxide	Cyclin-dependent kinase 2	Homo sapiens (human)
cellular senescence	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of anaphase-promoting complex-dependent catabolic process	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 2	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 2	Homo sapiens (human)
desensitization of G protein-coupled receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
negative regulation of the force of heart contraction by chemical signal	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled acetylcholine receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
tachykinin receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
heart development	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
viral genome replication	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
receptor internalization	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
positive regulation of catecholamine secretion	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
negative regulation of striated muscle contraction	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
symbiont entry into host cell	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
cardiac muscle contraction	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
negative regulation of relaxation of smooth muscle	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
regulation of the force of heart contraction	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
protein phosphorylation	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
P-body assembly	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
miRNA-mediated gene silencing by inhibition of translation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
negative regulation of translation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
viral RNA genome packaging	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
stem cell population maintenance	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
neuron differentiation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
P-body assembly	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
negative regulation of neuron differentiation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
stress granule assembly	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
positive regulation of protein phosphorylation	Activin receptor type-2A	Homo sapiens (human)
BMP signaling pathway	Activin receptor type-2A	Homo sapiens (human)
gastrulation with mouth forming second	Activin receptor type-2A	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Activin receptor type-2A	Homo sapiens (human)
spermatogenesis	Activin receptor type-2A	Homo sapiens (human)
determination of left/right symmetry	Activin receptor type-2A	Homo sapiens (human)
mesoderm development	Activin receptor type-2A	Homo sapiens (human)
anterior/posterior pattern specification	Activin receptor type-2A	Homo sapiens (human)
positive regulation of bone mineralization	Activin receptor type-2A	Homo sapiens (human)
BMP signaling pathway	Activin receptor type-2A	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-2A	Homo sapiens (human)
positive regulation of activin receptor signaling pathway	Activin receptor type-2A	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Activin receptor type-2A	Homo sapiens (human)
sperm ejaculation	Activin receptor type-2A	Homo sapiens (human)
penile erection	Activin receptor type-2A	Homo sapiens (human)
regulation of nitric oxide biosynthetic process	Activin receptor type-2A	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Activin receptor type-2A	Homo sapiens (human)
positive regulation of osteoblast differentiation	Activin receptor type-2A	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Activin receptor type-2A	Homo sapiens (human)
embryonic skeletal system development	Activin receptor type-2A	Homo sapiens (human)
Sertoli cell proliferation	Activin receptor type-2A	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Activin receptor type-2A	Homo sapiens (human)
cellular response to BMP stimulus	Activin receptor type-2A	Homo sapiens (human)
protein phosphorylation	Activin receptor type-2A	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-2A	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of macrophage proliferation	Mitogen-activated protein kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
DNA-templated transcription	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 3	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase 3	Homo sapiens (human)
insulin receptor signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
Schwann cell development	Mitogen-activated protein kinase 3	Homo sapiens (human)
phosphorylation	Mitogen-activated protein kinase 3	Homo sapiens (human)
sensory perception of pain	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of ossification	Mitogen-activated protein kinase 3	Homo sapiens (human)
BMP signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of cellular pH	Mitogen-activated protein kinase 3	Homo sapiens (human)
thyroid gland development	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of cyclase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 3	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Mitogen-activated protein kinase 3	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
outer ear morphogenesis	Mitogen-activated protein kinase 3	Homo sapiens (human)
myelination	Mitogen-activated protein kinase 3	Homo sapiens (human)
signal transduction in response to DNA damage	Mitogen-activated protein kinase 3	Homo sapiens (human)
response to exogenous dsRNA	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 3	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
thymus development	Mitogen-activated protein kinase 3	Homo sapiens (human)
modulation of chemical synaptic transmission	Mitogen-activated protein kinase 3	Homo sapiens (human)
cartilage development	Mitogen-activated protein kinase 3	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of cytoskeleton organization	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
Bergmann glial cell differentiation	Mitogen-activated protein kinase 3	Homo sapiens (human)
face development	Mitogen-activated protein kinase 3	Homo sapiens (human)
lung morphogenesis	Mitogen-activated protein kinase 3	Homo sapiens (human)
trachea formation	Mitogen-activated protein kinase 3	Homo sapiens (human)
cardiac neural crest cell development involved in heart development	Mitogen-activated protein kinase 3	Homo sapiens (human)
ERK1 and ERK2 cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
response to epidermal growth factor	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase 3	Homo sapiens (human)
caveolin-mediated endocytosis	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of Golgi inheritance	Mitogen-activated protein kinase 3	Homo sapiens (human)
xenophagy	Mitogen-activated protein kinase 3	Homo sapiens (human)
negative regulation of TORC1 signaling	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of xenophagy	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of early endosome to late endosome transport	Mitogen-activated protein kinase 3	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein phosphorylation	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
positive regulation of protein binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
negative regulation of hippo signaling	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
peptidyl-serine autophosphorylation	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
negative regulation of protein localization to nucleus	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
intracellular signal transduction	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
pyrimidine nucleotide metabolic process	Deoxycytidine kinase	Homo sapiens (human)
CMP biosynthetic process	Deoxycytidine kinase	Homo sapiens (human)
dAMP salvage	Deoxycytidine kinase	Homo sapiens (human)
nucleoside phosphate biosynthetic process	Deoxycytidine kinase	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of macrophage proliferation	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase 1	Homo sapiens (human)
chemotaxis	Mitogen-activated protein kinase 1	Homo sapiens (human)
DNA damage response	Mitogen-activated protein kinase 1	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 1	Homo sapiens (human)
chemical synaptic transmission	Mitogen-activated protein kinase 1	Homo sapiens (human)
learning or memory	Mitogen-activated protein kinase 1	Homo sapiens (human)
insulin receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
Schwann cell development	Mitogen-activated protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytosine metabolic process	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of ossification	Mitogen-activated protein kinase 1	Homo sapiens (human)
androgen receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of cellular pH	Mitogen-activated protein kinase 1	Homo sapiens (human)
thyroid gland development	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of protein stability	Mitogen-activated protein kinase 1	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Mitogen-activated protein kinase 1	Homo sapiens (human)
mammary gland epithelial cell proliferation	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 1	Homo sapiens (human)
response to nicotine	Mitogen-activated protein kinase 1	Homo sapiens (human)
ERBB signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
outer ear morphogenesis	Mitogen-activated protein kinase 1	Homo sapiens (human)
myelination	Mitogen-activated protein kinase 1	Homo sapiens (human)
response to exogenous dsRNA	Mitogen-activated protein kinase 1	Homo sapiens (human)
steroid hormone mediated signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
negative regulation of cell differentiation	Mitogen-activated protein kinase 1	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
thymus development	Mitogen-activated protein kinase 1	Homo sapiens (human)
progesterone receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
T cell receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
B cell receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of cytoskeleton organization	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
Bergmann glial cell differentiation	Mitogen-activated protein kinase 1	Homo sapiens (human)
long-term synaptic potentiation	Mitogen-activated protein kinase 1	Homo sapiens (human)
face development	Mitogen-activated protein kinase 1	Homo sapiens (human)
lung morphogenesis	Mitogen-activated protein kinase 1	Homo sapiens (human)
trachea formation	Mitogen-activated protein kinase 1	Homo sapiens (human)
labyrinthine layer blood vessel development	Mitogen-activated protein kinase 1	Homo sapiens (human)
cardiac neural crest cell development involved in heart development	Mitogen-activated protein kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Mitogen-activated protein kinase 1	Homo sapiens (human)
response to epidermal growth factor	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase 1	Homo sapiens (human)
caveolin-mediated endocytosis	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of Golgi inheritance	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of early endosome to late endosome transport	Mitogen-activated protein kinase 1	Homo sapiens (human)
cell surface receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 1	Homo sapiens (human)
skeletal system development	Ephrin type-A receptor 2	Homo sapiens (human)
vasculogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
osteoblast differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
inflammatory response	Ephrin type-A receptor 2	Homo sapiens (human)
cell adhesion	Ephrin type-A receptor 2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of lamellipodium assembly	Ephrin type-A receptor 2	Homo sapiens (human)
notochord formation	Ephrin type-A receptor 2	Homo sapiens (human)
cell migration	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of angiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
neural tube development	Ephrin type-A receptor 2	Homo sapiens (human)
neuron differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
keratinocyte differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
osteoclast differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of chemokine production	Ephrin type-A receptor 2	Homo sapiens (human)
mammary gland epithelial cell proliferation	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Ephrin type-A receptor 2	Homo sapiens (human)
post-anal tail morphogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of blood vessel endothelial cell migration	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of angiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
cAMP metabolic process	Ephrin type-A receptor 2	Homo sapiens (human)
symbiont entry into host cell	Ephrin type-A receptor 2	Homo sapiens (human)
bone remodeling	Ephrin type-A receptor 2	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 2	Homo sapiens (human)
axial mesoderm formation	Ephrin type-A receptor 2	Homo sapiens (human)
cell motility	Ephrin type-A receptor 2	Homo sapiens (human)
defense response to Gram-positive bacterium	Ephrin type-A receptor 2	Homo sapiens (human)
notochord cell development	Ephrin type-A receptor 2	Homo sapiens (human)
cell chemotaxis	Ephrin type-A receptor 2	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
lens fiber cell morphogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Ephrin type-A receptor 2	Homo sapiens (human)
response to growth factor	Ephrin type-A receptor 2	Homo sapiens (human)
protein localization to plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
activation of GTPase activity	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of lymphangiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of bicellular tight junction assembly	Ephrin type-A receptor 2	Homo sapiens (human)
pericyte cell differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Ephrin type-A receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Ephrin type-A receptor 2	Homo sapiens (human)
multicellular organism development	Ephrin type-A receptor 2	Homo sapiens (human)
cell adhesion	Ephrin type-A receptor 3	Homo sapiens (human)
regulation of epithelial to mesenchymal transition	Ephrin type-A receptor 3	Homo sapiens (human)
positive regulation of neuron projection development	Ephrin type-A receptor 3	Homo sapiens (human)
cell migration	Ephrin type-A receptor 3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Ephrin type-A receptor 3	Homo sapiens (human)
regulation of actin cytoskeleton organization	Ephrin type-A receptor 3	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-A receptor 3	Homo sapiens (human)
negative regulation of endocytosis	Ephrin type-A receptor 3	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 3	Homo sapiens (human)
regulation of focal adhesion assembly	Ephrin type-A receptor 3	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Ephrin type-A receptor 3	Homo sapiens (human)
cellular response to retinoic acid	Ephrin type-A receptor 3	Homo sapiens (human)
fasciculation of sensory neuron axon	Ephrin type-A receptor 3	Homo sapiens (human)
fasciculation of motor neuron axon	Ephrin type-A receptor 3	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Ephrin type-A receptor 3	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 3	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 3	Homo sapiens (human)
substrate-dependent cell migration	Ephrin type-A receptor 8	Homo sapiens (human)
cell adhesion	Ephrin type-A receptor 8	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 8	Homo sapiens (human)
neuron remodeling	Ephrin type-A receptor 8	Homo sapiens (human)
regulation of cell adhesion	Ephrin type-A receptor 8	Homo sapiens (human)
neuron projection development	Ephrin type-A receptor 8	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Ephrin type-A receptor 8	Homo sapiens (human)
positive regulation of MAPK cascade	Ephrin type-A receptor 8	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 8	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Ephrin type-A receptor 8	Homo sapiens (human)
cellular response to follicle-stimulating hormone stimulus	Ephrin type-A receptor 8	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 8	Homo sapiens (human)
negative regulation of protein kinase activity	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of autophagosome assembly	Ephrin type-B receptor 2	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
urogenital system development	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of protein phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of immunoglobulin production	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of cell adhesion	Ephrin type-B receptor 2	Homo sapiens (human)
nervous system development	Ephrin type-B receptor 2	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 2	Homo sapiens (human)
axonal fasciculation	Ephrin type-B receptor 2	Homo sapiens (human)
learning or memory	Ephrin type-B receptor 2	Homo sapiens (human)
learning	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of gene expression	Ephrin type-B receptor 2	Homo sapiens (human)
phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
optic nerve morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
hindbrain tangential cell migration	Ephrin type-B receptor 2	Homo sapiens (human)
central nervous system projection neuron axonogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
corpus callosum development	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of blood coagulation	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of B cell proliferation	Ephrin type-B receptor 2	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of synaptic plasticity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Ephrin type-B receptor 2	Homo sapiens (human)
B cell activation	Ephrin type-B receptor 2	Homo sapiens (human)
inner ear morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of receptor signaling pathway via JAK-STAT	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of Ras protein signal transduction	Ephrin type-B receptor 2	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of neuronal synaptic plasticity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of long-term neuronal synaptic plasticity	Ephrin type-B receptor 2	Homo sapiens (human)
camera-type eye morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of axonogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of body fluid levels	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of filopodium assembly	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of synapse assembly	Ephrin type-B receptor 2	Homo sapiens (human)
roof of mouth development	Ephrin type-B receptor 2	Homo sapiens (human)
dendritic spine development	Ephrin type-B receptor 2	Homo sapiens (human)
dendritic spine morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of dendritic spine morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Ephrin type-B receptor 2	Homo sapiens (human)
cellular response to lipopolysaccharide	Ephrin type-B receptor 2	Homo sapiens (human)
commissural neuron axon guidance	Ephrin type-B receptor 2	Homo sapiens (human)
postsynaptic membrane assembly	Ephrin type-B receptor 2	Homo sapiens (human)
trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	Ephrin type-B receptor 2	Homo sapiens (human)
neuron projection retraction	Ephrin type-B receptor 2	Homo sapiens (human)
vesicle-mediated intercellular transport	Ephrin type-B receptor 2	Homo sapiens (human)
tight junction assembly	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of cytokine production involved in inflammatory response	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of long-term synaptic potentiation	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Ephrin type-B receptor 2	Homo sapiens (human)
cellular response to amyloid-beta	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of NMDA glutamate receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of NMDA glutamate receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of protein localization to cell surface	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of T-helper 17 type immune response	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of behavioral fear response	Ephrin type-B receptor 2	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
protein phosphorylation	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
signal transduction	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
cell population proliferation	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
positive regulation of neuron projection development	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
negative regulation of apoptotic process	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
cellular response to retinoic acid	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
regulation of cell population proliferation	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
positive regulation of kinase activity	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
regulation of neuron differentiation	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
multicellular organism development	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
protein phosphorylation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
immune response	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytokine-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of type II interferon production	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of interleukin-17 production	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of natural killer cell proliferation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-12-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type III interferon-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of T cell proliferation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of NK T cell proliferation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type II interferon-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type I interferon-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cellular response to virus	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-10-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of protein localization to nucleus	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
intracellular signal transduction	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cell differentiation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
'de novo' pyrimidine nucleobase biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
UMP biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
UDP biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
pyrimidine ribonucleotide biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
nucleobase-containing small molecule interconversion	UMP-CMP kinase	Homo sapiens (human)
nucleoside monophosphate phosphorylation	UMP-CMP kinase	Homo sapiens (human)
CDP biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
negative regulation of MAPK cascade	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Wee1-like protein kinase	Homo sapiens (human)
microtubule cytoskeleton organization	Wee1-like protein kinase	Homo sapiens (human)
negative regulation of G2/M transition of mitotic cell cycle	Wee1-like protein kinase	Homo sapiens (human)
establishment of cell polarity	Wee1-like protein kinase	Homo sapiens (human)
positive regulation of DNA replication	Wee1-like protein kinase	Homo sapiens (human)
neuron projection morphogenesis	Wee1-like protein kinase	Homo sapiens (human)
cell division	Wee1-like protein kinase	Homo sapiens (human)
negative regulation of G1/S transition of mitotic cell cycle	Wee1-like protein kinase	Homo sapiens (human)
protein phosphorylation	Wee1-like protein kinase	Homo sapiens (human)
response to hypoxia	Heme oxygenase 2	Homo sapiens (human)
response to oxidative stress	Heme oxygenase 2	Homo sapiens (human)
heme catabolic process	Heme oxygenase 2	Homo sapiens (human)
heme oxidation	Heme oxygenase 2	Homo sapiens (human)
neuron migration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of cytokine-mediated signaling pathway	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
blood vessel remodeling	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
phagocytosis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
inflammatory response	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
spermatogenesis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of macrophage cytokine production	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
forebrain cell migration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
animal organ regeneration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of type II interferon production	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of tumor necrosis factor production	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of natural killer cell differentiation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
secretion by cell	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
erythrocyte homeostasis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cellular response to interferon-alpha	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
ovulation cycle	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of neuron apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
symbiont entry into host cell	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell maturation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of pinocytosis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
response to axon injury	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of lymphocyte activation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
neuron apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
establishment of localization in cell	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
vagina development	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cellular response to lipopolysaccharide	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
dendritic cell differentiation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
neutrophil clearance	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of viral life cycle	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of dendritic cell apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
natural killer cell differentiation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell migration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of kinase activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
nervous system development	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
multicellular organism development	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 4	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 4	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 4	Homo sapiens (human)
S-adenosylmethionine biosynthetic process	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
one-carbon metabolic process	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein hexamerization	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein heterooligomerization	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
cellular response to methionine	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
positive regulation of TORC1 signaling	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
cellular response to leukemia inhibitory factor	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein folding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
response to unfolded protein	DnaJ homolog subfamily A member 1	Homo sapiens (human)
spermatogenesis	DnaJ homolog subfamily A member 1	Homo sapiens (human)
response to heat	DnaJ homolog subfamily A member 1	Homo sapiens (human)
flagellated sperm motility	DnaJ homolog subfamily A member 1	Homo sapiens (human)
androgen receptor signaling pathway	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of protein ubiquitination	DnaJ homolog subfamily A member 1	Homo sapiens (human)
positive regulation of apoptotic process	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of apoptotic process	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of JUN kinase activity	DnaJ homolog subfamily A member 1	Homo sapiens (human)
regulation of protein transport	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein localization to mitochondrion	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of establishment of protein localization to mitochondrion	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein refolding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
activation-induced cell death of T cells	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
osteoblast differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
maternal placenta development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endothelial cell proliferation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
sphingosine-1-phosphate receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glycogen biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of glycogen biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glucose metabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of translation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein import into nucleus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nitric oxide biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
inflammatory response	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to oxidative stress	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
G protein-coupled receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
canonical NF-kappaB signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell population proliferation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
insulin receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
apoptotic mitochondrial changes	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to heat	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
gene expression	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of autophagy	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endothelial cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of gene expression	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of gene expression	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of long-chain fatty acid import across plasma membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
fibroblast migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of fibroblast migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of sodium ion transport	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose metabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of endopeptidase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of neuron projection development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of macroautophagy	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein ubiquitination	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-threonine phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
virus-mediated perturbation of host defense response	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cytokine-mediated signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
mammalian oogenesis stage	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell growth	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
T cell costimulation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein ubiquitination	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of myelination	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
TOR signaling	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of fatty acid beta-oxidation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endodeoxyribonuclease activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to food	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
peripheral nervous system myelin maintenance	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to insulin stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to fluid shear stress	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to reactive oxygen species	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
interleukin-18-mediated signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to decreased oxygen levels	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
non-canonical NF-kappaB signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glucose homeostasis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of apoptotic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of apoptotic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
anoikis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of mRNA stability	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of fat cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cyclin-dependent protein serine/threonine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of Notch signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of proteolysis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of DNA-templated transcription	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose import	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of organ growth	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein autophosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of lipid biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
behavioral response to pain	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of nitric-oxide synthase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
striated muscle cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein metabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
excitatory postsynaptic potential	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to growth hormone	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
mammary gland epithelial cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
labyrinthine layer blood vessel development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to UV-A	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to growth factor	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to cadmium ion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to tumor necrosis factor	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to prostaglandin E stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein serine/threonine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
establishment of protein localization to mitochondrion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
maintenance of protein location in mitochondrion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of release of cytochrome c from mitochondria	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to granulocyte macrophage colony-stimulating factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
execution phase of apoptosis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of postsynapse organization	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of tRNA methylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to oxidised low-density lipoprotein particle stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein localization to lysosome	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cGAS/STING signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to nucleus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to peptide	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cilium assembly	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of leukocyte cell-cell adhesion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of I-kappaB phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of TORC1 signaling	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to endoplasmic reticulum	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to nerve growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to insulin-like growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to cell surface	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of type B pancreatic cell development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of lymphocyte migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glycogen biosynthetic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
glucose metabolic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
regulation of translation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
insulin receptor signaling pathway	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of long-chain fatty acid import across plasma membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose metabolic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell migration	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell migration	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of fatty acid beta-oxidation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
peripheral nervous system myelin maintenance	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cellular response to insulin stimulus	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein modification process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
fat cell differentiation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose import	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell cycle	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
mammary gland epithelial cell differentiation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cellular response to high light intensity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
organic substance transport	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein localization to plasma membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein targeting to membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
retinal rod cell apoptotic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell motility	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	G protein-coupled receptor kinase 4	Homo sapiens (human)
regulation of G protein-coupled receptor signaling pathway	G protein-coupled receptor kinase 4	Homo sapiens (human)
regulation of opsin-mediated signaling pathway	G protein-coupled receptor kinase 4	Homo sapiens (human)
receptor internalization	G protein-coupled receptor kinase 4	Homo sapiens (human)
protein phosphorylation	G protein-coupled receptor kinase 4	Homo sapiens (human)
regulation of signal transduction	G protein-coupled receptor kinase 4	Homo sapiens (human)
spindle organization	Dual specificity protein kinase TTK	Homo sapiens (human)
mitotic spindle organization	Dual specificity protein kinase TTK	Homo sapiens (human)
positive regulation of cell population proliferation	Dual specificity protein kinase TTK	Homo sapiens (human)
female meiosis chromosome segregation	Dual specificity protein kinase TTK	Homo sapiens (human)
protein localization to meiotic spindle midzone	Dual specificity protein kinase TTK	Homo sapiens (human)
chromosome segregation	Dual specificity protein kinase TTK	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity protein kinase TTK	Homo sapiens (human)
protein localization to kinetochore	Dual specificity protein kinase TTK	Homo sapiens (human)
mitotic spindle assembly checkpoint signaling	Dual specificity protein kinase TTK	Homo sapiens (human)
meiotic spindle assembly checkpoint signaling	Dual specificity protein kinase TTK	Homo sapiens (human)
DNA replication	DNA replication licensing factor MCM4	Homo sapiens (human)
DNA unwinding involved in DNA replication	DNA replication licensing factor MCM4	Homo sapiens (human)
regulation of DNA-templated DNA replication initiation	DNA replication licensing factor MCM4	Homo sapiens (human)
double-strand break repair via break-induced replication	DNA replication licensing factor MCM4	Homo sapiens (human)
DNA strand elongation involved in DNA replication	DNA replication licensing factor MCM4	Homo sapiens (human)
mitotic DNA replication initiation	DNA replication licensing factor MCM4	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
prostaglandin biosynthetic process	Prostaglandin G/H synthase 2	Homo sapiens (human)
angiogenesis	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to oxidative stress	Prostaglandin G/H synthase 2	Homo sapiens (human)
embryo implantation	Prostaglandin G/H synthase 2	Homo sapiens (human)
learning	Prostaglandin G/H synthase 2	Homo sapiens (human)
memory	Prostaglandin G/H synthase 2	Homo sapiens (human)
regulation of blood pressure	Prostaglandin G/H synthase 2	Homo sapiens (human)
negative regulation of cell population proliferation	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to xenobiotic stimulus	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to nematode	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to fructose	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to manganese ion	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of vascular endothelial growth factor production	Prostaglandin G/H synthase 2	Homo sapiens (human)
cyclooxygenase pathway	Prostaglandin G/H synthase 2	Homo sapiens (human)
bone mineralization	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of prostaglandin biosynthetic process	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of fever generation	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of synaptic plasticity	Prostaglandin G/H synthase 2	Homo sapiens (human)
negative regulation of synaptic transmission, dopaminergic	Prostaglandin G/H synthase 2	Homo sapiens (human)
prostaglandin secretion	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to estradiol	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to lipopolysaccharide	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to vitamin D	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to heat	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to tumor necrosis factor	Prostaglandin G/H synthase 2	Homo sapiens (human)
maintenance of blood-brain barrier	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of protein import into nucleus	Prostaglandin G/H synthase 2	Homo sapiens (human)
hair cycle	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of apoptotic process	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Prostaglandin G/H synthase 2	Homo sapiens (human)
negative regulation of cell cycle	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of vasoconstriction	Prostaglandin G/H synthase 2	Homo sapiens (human)
negative regulation of smooth muscle contraction	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of smooth muscle contraction	Prostaglandin G/H synthase 2	Homo sapiens (human)
decidualization	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Prostaglandin G/H synthase 2	Homo sapiens (human)
regulation of inflammatory response	Prostaglandin G/H synthase 2	Homo sapiens (human)
brown fat cell differentiation	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to glucocorticoid	Prostaglandin G/H synthase 2	Homo sapiens (human)
negative regulation of calcium ion transport	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to fatty acid	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to mechanical stimulus	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to lead ion	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to ATP	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to hypoxia	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to non-ionic osmotic stress	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to fluid shear stress	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of transforming growth factor beta production	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of fibroblast growth factor production	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of brown fat cell differentiation	Prostaglandin G/H synthase 2	Homo sapiens (human)
positive regulation of platelet-derived growth factor production	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular oxidant detoxification	Prostaglandin G/H synthase 2	Homo sapiens (human)
regulation of neuroinflammatory response	Prostaglandin G/H synthase 2	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Prostaglandin G/H synthase 2	Homo sapiens (human)
cellular response to homocysteine	Prostaglandin G/H synthase 2	Homo sapiens (human)
response to angiotensin	Prostaglandin G/H synthase 2	Homo sapiens (human)
mitotic cytokinesis	Myosin-10	Homo sapiens (human)
actin filament-based movement	Myosin-10	Homo sapiens (human)
cell adhesion	Myosin-10	Homo sapiens (human)
actomyosin structure organization	Myosin-10	Homo sapiens (human)
positive regulation of protein secretion	Myosin-10	Homo sapiens (human)
mitotic cytokinesis	Myosin-10	Homo sapiens (human)
regulation of cell shape	Myosin-10	Homo sapiens (human)
regulation of extracellular matrix assembly	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
regulation of endothelial cell proliferation	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
lymphatic endothelial cell differentiation	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
angiogenesis	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
vasculogenesis	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
in utero embryonic development	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
aortic valve morphogenesis	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
negative regulation of angiogenesis	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
negative regulation of cell migration	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
response to retinoic acid	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
plasma membrane fusion	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
tissue remodeling	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
branching involved in lymph vessel morphogenesis	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
positive regulation of angiogenesis	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
positive regulation of kinase activity	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
multicellular organism development	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of protein phosphorylation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vasculature development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
lymph vessel development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
lymphangiogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
sprouting angiogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
respiratory system process	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of vascular endothelial growth factor production	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of endothelial cell migration	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
negative regulation of apoptotic process	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of JNK cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
lung alveolus development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
blood vessel morphogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
regulation of blood vessel remodeling	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of protein kinase C signaling	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
regulation of MAPK cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of macroautophagy	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mitochondrial depolarization	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mitochondrial fission	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
ovarian follicle development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vasculogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
lymph vessel development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
epithelial cell maturation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endocardium development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endothelium development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of cell shape	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
mesenchymal cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of gene expression	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of BMP signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
embryonic hemopoiesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor-2 signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
surfactant homeostasis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of neuron apoptotic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell fate commitment	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
lung alveolus development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
post-embryonic camera-type eye morphogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
epithelial cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of positive chemotaxis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of focal adhesion assembly	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
calcium ion homeostasis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
blood vessel endothelial cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular wound healing	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
semaphorin-plexin signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
stem cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of hematopoietic progenitor cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of bone development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cellular response to hydrogen sulfide	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of stem cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of vasculogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of MAPK cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endothelial cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of gene expression	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
Schwann cell development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
thyroid gland development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
peptidyl-serine autophosphorylation	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
myelination	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
thymus development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of axon regeneration	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of axonogenesis	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
face development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
trachea formation	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
epithelial cell proliferation involved in lung morphogenesis	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of Golgi inheritance	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of cell motility	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of early endosome to late endosome transport	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
hemopoiesis	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
leukocyte homeostasis	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
myeloid progenitor cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
pro-B cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of cell population proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
response to organonitrogen compound	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytokine-mediated signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
B cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
animal organ regeneration	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
common myeloid progenitor cell proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
regulation of apoptotic process	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of MAP kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of MAPK cascade	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
lymphocyte proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein autophosphorylation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cellular response to cytokine stimulus	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cellular response to glucocorticoid stimulus	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
dendritic cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
multicellular organism development	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
regulation of cardiac muscle cell apoptotic process	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of neural crest cell differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of gene expression	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of gene expression	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of transforming growth factor beta2 production	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
angiogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
osteoblast differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
in utero embryonic development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
mesoderm formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
somitogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
Mullerian duct regression	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
chondrocyte differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
outflow tract septum morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
outflow tract morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cardiac conduction system development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
atrioventricular valve development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
mitral valve morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
tricuspid valve morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
endocardial cushion morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cardiac right ventricle morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ventricular trabecula myocardium morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ventricular compact myocardium morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
endocardial cushion formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
immune response	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ectoderm development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dorsal/ventral axis specification	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
neural crest cell development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of smooth muscle cell migration	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
central nervous system neuron differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
pituitary gland development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
neural plate mediolateral regionalization	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
lung development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of bone mineralization	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
BMP signaling pathway	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
somatic stem cell population maintenance	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
hindlimb morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dorsal aorta morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
embryonic digit morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of osteoblast differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
paraxial mesoderm structural organization	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
lateral mesoderm development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of lateral mesodermal cell fate specification	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
mesendoderm development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
embryonic organ development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
developmental growth	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
epithelial cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of neurogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of muscle cell differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
roof of mouth development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of cardiac muscle cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ventricular septum morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
heart formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
atrioventricular node cell development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
pharyngeal arch artery morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cellular response to BMP stimulus	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of miRNA transcription	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of cardiac ventricle development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
fibrous ring of heart morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of cellular senescence	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
protein phosphorylation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dorsal/ventral pattern formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cellular response to growth factor stimulus	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Activin receptor type-1B	Homo sapiens (human)
in utero embryonic development	Activin receptor type-1B	Homo sapiens (human)
hair follicle development	Activin receptor type-1B	Homo sapiens (human)
regulation of DNA-templated transcription	Activin receptor type-1B	Homo sapiens (human)
signal transduction	Activin receptor type-1B	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of gene expression	Activin receptor type-1B	Homo sapiens (human)
negative regulation of gene expression	Activin receptor type-1B	Homo sapiens (human)
peptidyl-threonine phosphorylation	Activin receptor type-1B	Homo sapiens (human)
negative regulation of cell growth	Activin receptor type-1B	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of activin receptor signaling pathway	Activin receptor type-1B	Homo sapiens (human)
nodal signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Activin receptor type-1B	Homo sapiens (human)
protein autophosphorylation	Activin receptor type-1B	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of trophoblast cell migration	Activin receptor type-1B	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-1B	Homo sapiens (human)
protein phosphorylation	Activin receptor type-1B	Homo sapiens (human)
nervous system development	Activin receptor type-1B	Homo sapiens (human)
proepicardium development	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of cell migration	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of extracellular matrix assembly	TGF-beta receptor type-1	Homo sapiens (human)
skeletal system development	TGF-beta receptor type-1	Homo sapiens (human)
in utero embryonic development	TGF-beta receptor type-1	Homo sapiens (human)
kidney development	TGF-beta receptor type-1	Homo sapiens (human)
blastocyst development	TGF-beta receptor type-1	Homo sapiens (human)
epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
endothelial cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of endothelial cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of endothelial cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
lens development in camera-type eye	TGF-beta receptor type-1	Homo sapiens (human)
ventricular trabecula myocardium morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
ventricular compact myocardium morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
regulation of DNA-templated transcription	TGF-beta receptor type-1	Homo sapiens (human)
apoptotic process	TGF-beta receptor type-1	Homo sapiens (human)
signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
heart development	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of cell population proliferation	TGF-beta receptor type-1	Homo sapiens (human)
germ cell migration	TGF-beta receptor type-1	Homo sapiens (human)
male gonad development	TGF-beta receptor type-1	Homo sapiens (human)
post-embryonic development	TGF-beta receptor type-1	Homo sapiens (human)
anterior/posterior pattern specification	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of gene expression	TGF-beta receptor type-1	Homo sapiens (human)
regulation of epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
peptidyl-serine phosphorylation	TGF-beta receptor type-1	Homo sapiens (human)
collagen fibril organization	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of cell growth	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of cell migration	TGF-beta receptor type-1	Homo sapiens (human)
regulation of protein ubiquitination	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of chondrocyte differentiation	TGF-beta receptor type-1	Homo sapiens (human)
activin receptor signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
intracellular signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
myofibroblast differentiation	TGF-beta receptor type-1	Homo sapiens (human)
wound healing	TGF-beta receptor type-1	Homo sapiens (human)
endothelial cell activation	TGF-beta receptor type-1	Homo sapiens (human)
extracellular structure organization	TGF-beta receptor type-1	Homo sapiens (human)
endothelial cell migration	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	TGF-beta receptor type-1	Homo sapiens (human)
filopodium assembly	TGF-beta receptor type-1	Homo sapiens (human)
thymus development	TGF-beta receptor type-1	Homo sapiens (human)
neuron fate commitment	TGF-beta receptor type-1	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
skeletal system morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
mesenchymal cell differentiation	TGF-beta receptor type-1	Homo sapiens (human)
artery morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
cell motility	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of filopodium assembly	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of stress fiber assembly	TGF-beta receptor type-1	Homo sapiens (human)
regulation of cell cycle	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
parathyroid gland development	TGF-beta receptor type-1	Homo sapiens (human)
roof of mouth development	TGF-beta receptor type-1	Homo sapiens (human)
pharyngeal system development	TGF-beta receptor type-1	Homo sapiens (human)
regulation of cardiac muscle cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
cardiac epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
ventricular septum morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
angiogenesis involved in coronary vascular morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
coronary artery morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
response to cholesterol	TGF-beta receptor type-1	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of mesenchymal stem cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of vasculature development	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of tight junction disassembly	TGF-beta receptor type-1	Homo sapiens (human)
epicardium morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
protein phosphorylation	TGF-beta receptor type-1	Homo sapiens (human)
cellular response to growth factor stimulus	TGF-beta receptor type-1	Homo sapiens (human)
nervous system development	TGF-beta receptor type-1	Homo sapiens (human)
endocardial cushion to mesenchymal transition	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of epithelial cell differentiation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of Notch signaling pathway	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
angiogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
response to hypoxia	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
in utero embryonic development	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
regulation of endothelial cell proliferation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of endothelial cell proliferation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
lymphangiogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
blood vessel maturation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
blood vessel remodeling	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
endocardial cushion morphogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
regulation of DNA replication	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
regulation of DNA-templated transcription	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of cell adhesion	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
blood circulation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
regulation of blood pressure	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of cell population proliferation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of endothelial cell migration	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of gene expression	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of cell growth	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of cell migration	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
BMP signaling pathway	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of BMP signaling pathway	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of chondrocyte differentiation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
activin receptor signaling pathway	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
wound healing, spreading of epidermal cells	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
dorsal aorta morphogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
regulation of blood vessel endothelial cell migration	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of blood vessel endothelial cell migration	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of endothelial cell differentiation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of endothelial cell differentiation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
negative regulation of focal adhesion assembly	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
lymphatic endothelial cell differentiation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
artery development	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
venous blood vessel development	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
endothelial tube morphogenesis	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
retina vasculature development in camera-type eye	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
cellular response to BMP stimulus	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
positive regulation of bicellular tight junction assembly	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
dorsal/ventral pattern formation	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
heart development	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
cellular response to growth factor stimulus	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
cell proliferation involved in endocardial cushion morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
superior endocardial cushion morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
blood vessel development	TGF-beta receptor type-2	Homo sapiens (human)
branching involved in blood vessel morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
vasculogenesis	TGF-beta receptor type-2	Homo sapiens (human)
in utero embryonic development	TGF-beta receptor type-2	Homo sapiens (human)
epithelial to mesenchymal transition	TGF-beta receptor type-2	Homo sapiens (human)
heart looping	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	TGF-beta receptor type-2	Homo sapiens (human)
lens development in camera-type eye	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of tolerance induction to self antigen	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of B cell tolerance induction	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of T cell tolerance induction	TGF-beta receptor type-2	Homo sapiens (human)
outflow tract septum morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
membranous septum morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
outflow tract morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
aortic valve morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
atrioventricular valve morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
tricuspid valve morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
cardiac left ventricle morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
endocardial cushion fusion	TGF-beta receptor type-2	Homo sapiens (human)
growth plate cartilage chondrocyte growth	TGF-beta receptor type-2	Homo sapiens (human)
apoptotic process	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
Notch signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
smoothened signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
gastrulation	TGF-beta receptor type-2	Homo sapiens (human)
brain development	TGF-beta receptor type-2	Homo sapiens (human)
heart development	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of cell population proliferation	TGF-beta receptor type-2	Homo sapiens (human)
response to xenobiotic stimulus	TGF-beta receptor type-2	Homo sapiens (human)
regulation of gene expression	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of epithelial cell migration	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	TGF-beta receptor type-2	Homo sapiens (human)
activation of protein kinase activity	TGF-beta receptor type-2	Homo sapiens (human)
activin receptor signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
embryonic hemopoiesis	TGF-beta receptor type-2	Homo sapiens (human)
aorta morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
regulation of cell population proliferation	TGF-beta receptor type-2	Homo sapiens (human)
myeloid dendritic cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of angiogenesis	TGF-beta receptor type-2	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
artery morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of NK T cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
roof of mouth development	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	TGF-beta receptor type-2	Homo sapiens (human)
SMAD protein signal transduction	TGF-beta receptor type-2	Homo sapiens (human)
ventricular septum morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
bronchus morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
trachea formation	TGF-beta receptor type-2	Homo sapiens (human)
mammary gland morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
lung lobe morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
Langerhans cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
secondary palate development	TGF-beta receptor type-2	Homo sapiens (human)
response to cholesterol	TGF-beta receptor type-2	Homo sapiens (human)
regulation of stem cell proliferation	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	TGF-beta receptor type-2	Homo sapiens (human)
inferior endocardial cushion morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
lens fiber cell apoptotic process	TGF-beta receptor type-2	Homo sapiens (human)
miRNA transport	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	TGF-beta receptor type-2	Homo sapiens (human)
regulation of stem cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
cellular response to growth factor stimulus	TGF-beta receptor type-2	Homo sapiens (human)
protein phosphorylation	TGF-beta receptor type-2	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of low-density lipoprotein particle clearance	Tyrosine-protein kinase CSK	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of interleukin-6 production	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of Golgi to plasma membrane protein transport	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of bone resorption	Tyrosine-protein kinase CSK	Homo sapiens (human)
oligodendrocyte differentiation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of phagocytosis	Tyrosine-protein kinase CSK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase CSK	Homo sapiens (human)
cellular response to peptide hormone stimulus	Tyrosine-protein kinase CSK	Homo sapiens (human)
regulation of Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase CSK	Homo sapiens (human)
adherens junction organization	Tyrosine-protein kinase CSK	Homo sapiens (human)
tRNA aminoacylation for protein translation	Glycine--tRNA ligase	Homo sapiens (human)
diadenosine tetraphosphate biosynthetic process	Glycine--tRNA ligase	Homo sapiens (human)
mitochondrial glycyl-tRNA aminoacylation	Glycine--tRNA ligase	Homo sapiens (human)
protein phosphorylation	Protein kinase C iota type	Homo sapiens (human)
protein targeting to membrane	Protein kinase C iota type	Homo sapiens (human)
cytoskeleton organization	Protein kinase C iota type	Homo sapiens (human)
actin filament organization	Protein kinase C iota type	Homo sapiens (human)
positive regulation of neuron projection development	Protein kinase C iota type	Homo sapiens (human)
vesicle-mediated transport	Protein kinase C iota type	Homo sapiens (human)
cell migration	Protein kinase C iota type	Homo sapiens (human)
cellular response to insulin stimulus	Protein kinase C iota type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C iota type	Homo sapiens (human)
establishment of apical/basal cell polarity	Protein kinase C iota type	Homo sapiens (human)
eye photoreceptor cell development	Protein kinase C iota type	Homo sapiens (human)
negative regulation of apoptotic process	Protein kinase C iota type	Homo sapiens (human)
negative regulation of neuron apoptotic process	Protein kinase C iota type	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Protein kinase C iota type	Homo sapiens (human)
cell-cell junction organization	Protein kinase C iota type	Homo sapiens (human)
positive regulation of Notch signaling pathway	Protein kinase C iota type	Homo sapiens (human)
positive regulation of glucose import	Protein kinase C iota type	Homo sapiens (human)
secretion	Protein kinase C iota type	Homo sapiens (human)
Golgi vesicle budding	Protein kinase C iota type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C iota type	Homo sapiens (human)
positive regulation of glial cell proliferation	Protein kinase C iota type	Homo sapiens (human)
membrane organization	Protein kinase C iota type	Homo sapiens (human)
cellular response to chemical stress	Protein kinase C iota type	Homo sapiens (human)
response to interleukin-1	Protein kinase C iota type	Homo sapiens (human)
regulation of postsynaptic membrane neurotransmitter receptor levels	Protein kinase C iota type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C iota type	Homo sapiens (human)
positive regulation of endothelial cell apoptotic process	Protein kinase C iota type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C iota type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C iota type	Homo sapiens (human)
mRNA splicing, via spliceosome	Exosome RNA helicase MTR4	Homo sapiens (human)
maturation of 5.8S rRNA	Exosome RNA helicase MTR4	Homo sapiens (human)
rRNA processing	Exosome RNA helicase MTR4	Homo sapiens (human)
RNA catabolic process	Exosome RNA helicase MTR4	Homo sapiens (human)
DNA damage response	Exosome RNA helicase MTR4	Homo sapiens (human)
snRNA catabolic process	Exosome RNA helicase MTR4	Homo sapiens (human)
phosphorylation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
angiogenesis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
liver development	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
regulation of protein phosphorylation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
vasculature development	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
glucose metabolic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phagocytosis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
insulin receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
positive regulation of lamellipodium assembly	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
negative regulation of gene expression	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
response to activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
response to muscle inactivity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
negative regulation of macroautophagy	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
actin cytoskeleton organization	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
platelet activation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
negative regulation of actin filament depolymerization	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
T cell costimulation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
positive regulation of TOR signaling	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cellular response to insulin stimulus	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
response to muscle stretch	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
regulation of multicellular organism growth	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
response to L-leucine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
anoikis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
regulation of cellular respiration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
negative regulation of neuron apoptotic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
endothelial cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
T cell receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
relaxation of cardiac muscle	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cardiac muscle contraction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
adipose tissue development	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cellular response to glucose stimulus	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cellular response to hydrostatic pressure	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
response to dexamethasone	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cardiac muscle cell contraction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
energy homeostasis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
regulation of actin filament organization	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
autosome genomic imprinting	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
response to butyrate	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
positive regulation of protein localization to membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
negative regulation of fibroblast apoptotic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
negative regulation of anoikis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol-3-phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
regulation of cell-matrix adhesion	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
positive regulation of gene expression	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphorylation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
endothelial cell proliferation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
response to ischemia	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
sphingosine-1-phosphate receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
intracellular calcium ion homeostasis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
endocytosis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
autophagy	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
homophilic cell adhesion via plasma membrane adhesion molecules	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
positive regulation of autophagy	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
positive regulation of endothelial cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
platelet activation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
positive regulation of neutrophil apoptotic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
positive regulation of Rac protein signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
embryonic cleavage	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
negative regulation of MAPK cascade	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
angiogenesis involved in wound healing	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
platelet aggregation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
negative regulation of vascular endothelial growth factor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
negative regulation of sprouting angiogenesis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphatidylinositol-3-phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
protein destabilization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of macroautophagy	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
T-helper 1 cell lineage commitment	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
heart morphogenesis	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
heart valve morphogenesis	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
energy reserve metabolic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
'de novo' pyrimidine nucleobase biosynthetic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
inflammatory response	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
lysosome organization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
germ cell development	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
response to nutrient	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of cell size	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to starvation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
response to heat	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
post-embryonic development	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of autophagy	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of lamellipodium assembly	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of gene expression	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of myotube differentiation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
macroautophagy	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of macroautophagy	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
neuronal action potential	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein catabolic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of cell growth	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of actin filament polymerization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
T cell costimulation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
ruffle organization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of myelination	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
response to nutrient levels	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to nutrient levels	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to nutrient	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
TOR signaling	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of phosphoprotein phosphatase activity	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to insulin stimulus	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
calcineurin-NFAT signaling cascade	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to amino acid starvation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
multicellular organism growth	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
TORC1 signaling	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of circadian rhythm	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
response to amino acid	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
anoikis	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of osteoclast differentiation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of translation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of cell size	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of glycolytic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of transcription by RNA polymerase III	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of translational initiation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of lipid biosynthetic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
behavioral response to pain	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
rhythmic process	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
oligodendrocyte differentiation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of oligodendrocyte differentiation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
voluntary musculoskeletal movement	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of stress fiber assembly	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of keratinocyte migration	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
nucleus localization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cardiac muscle cell development	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cardiac muscle contraction	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to methionine	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of calcineurin-NFAT signaling cascade	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to amino acid stimulus	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to L-leucine	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to hypoxia	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to osmotic stress	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of membrane permeability	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of cellular response to heat	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of protein localization to nucleus	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of wound healing, spreading of epidermal cells	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of locomotor rhythm	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of cytoplasmic translational initiation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of lysosome organization	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
positive regulation of pentose-phosphate shunt	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cellular response to leucine starvation	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
regulation of autophagosome assembly	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
negative regulation of macroautophagy	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein phosphorylation	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
positive regulation of cell population proliferation	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Tec	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase Tec	Homo sapiens (human)
regulation of platelet activation	Tyrosine-protein kinase Tec	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Tec	Homo sapiens (human)
tissue regeneration	Tyrosine-protein kinase Tec	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Tec	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Tec	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Tec	Homo sapiens (human)
positive regulation of cytokine production	Tyrosine-protein kinase TXK	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase TXK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase TXK	Homo sapiens (human)
activation of phospholipase C activity	Tyrosine-protein kinase TXK	Homo sapiens (human)
regulation of gene expression	Tyrosine-protein kinase TXK	Homo sapiens (human)
positive regulation of type II interferon production	Tyrosine-protein kinase TXK	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase TXK	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase TXK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase TXK	Homo sapiens (human)
positive regulation of type II interferon-mediated signaling pathway	Tyrosine-protein kinase TXK	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of phospholipase C activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
negative regulation of Rho protein signal transduction	Tyrosine-protein kinase ABL2	Homo sapiens (human)
exploration behavior	Tyrosine-protein kinase ABL2	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase ABL2	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of autophagy	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase ABL2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of endocytosis	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of cell adhesion	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of oxidoreductase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of establishment of T cell polarity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of cell motility	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of T cell migration	Tyrosine-protein kinase ABL2	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ABL2	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Tyrosine-protein kinase FRK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase FRK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase FRK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase FRK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase FRK	Homo sapiens (human)
positive regulation of synaptic transmission, GABAergic	Carbonic anhydrase 7	Homo sapiens (human)
positive regulation of cellular pH reduction	Carbonic anhydrase 7	Homo sapiens (human)
neuron cellular homeostasis	Carbonic anhydrase 7	Homo sapiens (human)
regulation of chloride transport	Carbonic anhydrase 7	Homo sapiens (human)
regulation of intracellular pH	Carbonic anhydrase 7	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 7	Homo sapiens (human)
G protein-coupled receptor signaling pathway	G protein-coupled receptor kinase 6	Homo sapiens (human)
regulation of G protein-coupled receptor signaling pathway	G protein-coupled receptor kinase 6	Homo sapiens (human)
Wnt signaling pathway	G protein-coupled receptor kinase 6	Homo sapiens (human)
regulation of signal transduction	G protein-coupled receptor kinase 6	Homo sapiens (human)
protein phosphorylation	G protein-coupled receptor kinase 6	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive thymic T cell selection	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of T cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
immune response	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
calcium-mediated signaling	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell activation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
B cell activation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
beta selection	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
negative thymic T cell selection	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of alpha-beta T cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of alpha-beta T cell proliferation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell aggregation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell migration	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein import into nucleus	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
angiogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
cell activation	Tyrosine-protein kinase SYK	Homo sapiens (human)
lymph vessel development	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of receptor internalization	Tyrosine-protein kinase SYK	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
macrophage activation involved in immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
neutrophil activation involved in immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
leukocyte activation involved in immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
serotonin secretion by platelet	Tyrosine-protein kinase SYK	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase SYK	Homo sapiens (human)
leukocyte cell-cell adhesion	Tyrosine-protein kinase SYK	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
animal organ morphogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of platelet activation	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase SYK	Homo sapiens (human)
leukotriene biosynthetic process	Tyrosine-protein kinase SYK	Homo sapiens (human)
calcium-mediated signaling	Tyrosine-protein kinase SYK	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase SYK	Homo sapiens (human)
B cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
neutrophil chemotaxis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of protein-containing complex assembly	Tyrosine-protein kinase SYK	Homo sapiens (human)
receptor internalization	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of type I interferon production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of granulocyte macrophage colony-stimulating factor production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-10 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-12 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-3 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-4 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-6 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-8 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of mast cell cytokine production	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of superoxide anion generation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of superoxide anion generation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of cell adhesion mediated by integrin	Tyrosine-protein kinase SYK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase SYK	Homo sapiens (human)
collagen-activated tyrosine kinase receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase SYK	Homo sapiens (human)
interleukin-3-mediated signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
gamma-delta T cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
defense response to bacterium	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase SYK	Homo sapiens (human)
mast cell degranulation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of mast cell degranulation	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of neutrophil degranulation	Tyrosine-protein kinase SYK	Homo sapiens (human)
beta selection	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase SYK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of B cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of gamma-delta T cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of bone resorption	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of alpha-beta T cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of alpha-beta T cell proliferation	Tyrosine-protein kinase SYK	Homo sapiens (human)
blood vessel morphogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of phagocytosis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Tyrosine-protein kinase SYK	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of killing of cells of another organism	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to molecule of fungal origin	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to lipid	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to low-density lipoprotein particle stimulus	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of monocyte chemotactic protein-1 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of arachidonic acid secretion	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of platelet aggregation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of TORC1 signaling	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to lectin	Tyrosine-protein kinase SYK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
blastocyst development	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteolysis	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	26S proteasome regulatory subunit 6B	Homo sapiens (human)
positive regulation of proteasomal protein catabolic process	26S proteasome regulatory subunit 6B	Homo sapiens (human)
JUN phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
response to UV	Mitogen-activated protein kinase 8	Homo sapiens (human)
negative regulation of apoptotic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to lipopolysaccharide	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
response to oxidative stress	Mitogen-activated protein kinase 8	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase 8	Homo sapiens (human)
JUN phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 8	Homo sapiens (human)
regulation of macroautophagy	Mitogen-activated protein kinase 8	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
peptidyl-threonine phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of cyclase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of cell killing	Mitogen-activated protein kinase 8	Homo sapiens (human)
negative regulation of protein binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
regulation of protein localization	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to oxidative stress	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 8	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase 8	Homo sapiens (human)
regulation of circadian rhythm	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
negative regulation of apoptotic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
rhythmic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of protein metabolic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 8	Homo sapiens (human)
energy homeostasis	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Mitogen-activated protein kinase 8	Homo sapiens (human)
response to mechanical stimulus	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of establishment of protein localization to mitochondrion	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 9	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of macrophage derived foam cell differentiation	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of protein ubiquitination	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Mitogen-activated protein kinase 9	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 9	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase 9	Homo sapiens (human)
regulation of circadian rhythm	Mitogen-activated protein kinase 9	Homo sapiens (human)
rhythmic process	Mitogen-activated protein kinase 9	Homo sapiens (human)
modulation of chemical synaptic transmission	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein localization to tricellular tight junction	Mitogen-activated protein kinase 9	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of podosome assembly	Mitogen-activated protein kinase 9	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 9	Homo sapiens (human)
inflammatory response to wounding	Mitogen-activated protein kinase 9	Homo sapiens (human)
apoptotic signaling pathway	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of cytokine production involved in inflammatory response	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of protein phosphorylation	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
JNK cascade	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
response to wounding	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
smooth muscle cell apoptotic process	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
positive regulation of neuron apoptotic process	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
positive regulation of DNA replication	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
positive regulation of JNK cascade	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
cell growth involved in cardiac muscle cell development	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
cellular response to mechanical stimulus	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
cellular response to sorbitol	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
negative regulation of motor neuron apoptotic process	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
regulation of cytokine production	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
response to ischemia	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
inflammatory response	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
negative regulation of hippo signaling	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
p38MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cardiac muscle contraction	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular response to lipopolysaccharide	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular response to sorbitol	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
regulation of autophagy	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
megakaryocyte development	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
autophagosome-lysosome fusion	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
vesicle-mediated cholesterol transport	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
positive regulation of autophagosome assembly	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform alpha	Homo sapiens (human)
Golgi organization	Casein kinase I isoform alpha	Homo sapiens (human)
cell surface receptor signaling pathway	Casein kinase I isoform alpha	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform alpha	Homo sapiens (human)
viral protein processing	Casein kinase I isoform alpha	Homo sapiens (human)
cellular response to nutrient	Casein kinase I isoform alpha	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase I isoform alpha	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Casein kinase I isoform alpha	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Casein kinase I isoform alpha	Homo sapiens (human)
intermediate filament cytoskeleton organization	Casein kinase I isoform alpha	Homo sapiens (human)
cell division	Casein kinase I isoform alpha	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Casein kinase I isoform alpha	Homo sapiens (human)
negative regulation of NLRP3 inflammasome complex assembly	Casein kinase I isoform alpha	Homo sapiens (human)
positive regulation of TORC1 signaling	Casein kinase I isoform alpha	Homo sapiens (human)
signal transduction	Casein kinase I isoform alpha	Homo sapiens (human)
microtubule nucleation	Casein kinase I isoform delta	Homo sapiens (human)
Golgi organization	Casein kinase I isoform delta	Homo sapiens (human)
protein localization to Golgi apparatus	Casein kinase I isoform delta	Homo sapiens (human)
protein localization to cilium	Casein kinase I isoform delta	Homo sapiens (human)
protein localization to centrosome	Casein kinase I isoform delta	Homo sapiens (human)
non-motile cilium assembly	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of protein phosphorylation	Casein kinase I isoform delta	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform delta	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase I isoform delta	Homo sapiens (human)
circadian regulation of gene expression	Casein kinase I isoform delta	Homo sapiens (human)
regulation of circadian rhythm	Casein kinase I isoform delta	Homo sapiens (human)
COPII vesicle coating	Casein kinase I isoform delta	Homo sapiens (human)
spindle assembly	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform delta	Homo sapiens (human)
midbrain dopaminergic neuron differentiation	Casein kinase I isoform delta	Homo sapiens (human)
cellular response to nerve growth factor stimulus	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of non-canonical Wnt signaling pathway	Casein kinase I isoform delta	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform delta	Homo sapiens (human)
signal transduction	Casein kinase I isoform delta	Homo sapiens (human)
non-motile cilium assembly	Casein kinase I isoform delta	Homo sapiens (human)
endocytosis	Casein kinase I isoform delta	Homo sapiens (human)
phosphorylation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
angiogenesis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of cytokine production	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
adaptive immune response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
dendritic cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of acute inflammatory response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
respiratory burst involved in defense response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
sphingosine-1-phosphate receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
endocytosis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
inflammatory response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
immune response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of endothelial cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
T cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
negative regulation of triglyceride catabolic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
neutrophil chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
secretory granule localization	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of Rac protein signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
natural killer cell chemotaxis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
T cell proliferation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
T cell activation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
mast cell degranulation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of MAP kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
innate immune response	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
regulation of angiogenesis	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
negative regulation of cardiac muscle contraction	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
platelet aggregation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
cellular response to cAMP	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
neutrophil extravasation	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
hepatocyte apoptotic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
regulation of calcium ion transmembrane transport	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
negative regulation of fibroblast apoptotic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
cell migration	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phosphatidylinositol-3-phosphate biosynthetic process	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
MAPK cascade	MAP kinase-activated protein kinase 2	Homo sapiens (human)
toll-like receptor signaling pathway	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein phosphorylation	MAP kinase-activated protein kinase 2	Homo sapiens (human)
leukotriene metabolic process	MAP kinase-activated protein kinase 2	Homo sapiens (human)
inflammatory response	MAP kinase-activated protein kinase 2	Homo sapiens (human)
DNA damage response	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	MAP kinase-activated protein kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP kinase-activated protein kinase 2	Homo sapiens (human)
response to lipopolysaccharide	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of interleukin-6 production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of tumor necrosis factor production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
response to cytokine	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	MAP kinase-activated protein kinase 2	Homo sapiens (human)
p38MAPK cascade	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of mRNA stability	MAP kinase-activated protein kinase 2	Homo sapiens (human)
macropinocytosis	MAP kinase-activated protein kinase 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	MAP kinase-activated protein kinase 2	Homo sapiens (human)
inner ear development	MAP kinase-activated protein kinase 2	Homo sapiens (human)
positive regulation of macrophage cytokine production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of cellular response to heat	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein autophosphorylation	MAP kinase-activated protein kinase 2	Homo sapiens (human)
intracellular signal transduction	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein ubiquitination	Cyclin-dependent kinase 8	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 8	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 8	Homo sapiens (human)
negative regulation of triglyceride metabolic process	Cyclin-dependent kinase 8	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 8	Homo sapiens (human)
translational elongation	Elongation factor Tu, mitochondrial	Homo sapiens (human)
response to ethanol	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrial translational elongation	Elongation factor Tu, mitochondrial	Homo sapiens (human)
cysteinyl-tRNA aminoacylation	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
DNA repair	Casein kinase I isoform epsilon	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform epsilon	Homo sapiens (human)
protein localization	Casein kinase I isoform epsilon	Homo sapiens (human)
negative regulation of Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
negative regulation of protein binding	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase I isoform epsilon	Homo sapiens (human)
regulation of protein localization	Casein kinase I isoform epsilon	Homo sapiens (human)
circadian regulation of gene expression	Casein kinase I isoform epsilon	Homo sapiens (human)
regulation of circadian rhythm	Casein kinase I isoform epsilon	Homo sapiens (human)
circadian behavior	Casein kinase I isoform epsilon	Homo sapiens (human)
canonical Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of amyloid-beta formation	Casein kinase I isoform epsilon	Homo sapiens (human)
cellular response to nerve growth factor stimulus	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of non-canonical Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform epsilon	Homo sapiens (human)
endocytosis	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
signal transduction	Casein kinase I isoform epsilon	Homo sapiens (human)
temperature homeostasis	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
response to cold	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
energy derivation by oxidation of organic compounds	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
epithelial cell differentiation	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
negative regulation of fatty acid biosynthetic process	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
negative regulation of fatty acid oxidation	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
regulation of cholesterol metabolic process	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein phosphorylation	Dual specificity protein kinase CLK2	Homo sapiens (human)
response to ionizing radiation	Dual specificity protein kinase CLK2	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK2	Homo sapiens (human)
negative regulation of gluconeogenesis	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein autophosphorylation	Dual specificity protein kinase CLK2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein phosphorylation	Dual specificity protein kinase CLK3	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK3	Homo sapiens (human)
regulation of systemic arterial blood pressure	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cardiac left ventricle morphogenesis	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
glycogen metabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
dopamine receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
nervous system development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
insulin receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of autophagy	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of gene expression	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of UDP-glucose catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
Wnt signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cell migration	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
peptidyl-threonine phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
viral protein processing	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of protein ubiquitination	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of TOR signaling	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to insulin stimulus	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to interleukin-3	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glycogen biosynthetic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of protein catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of heart contraction	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glucose import	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
excitatory postsynaptic potential	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of cell growth involved in cardiac muscle cell development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to lithium ion	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to glucocorticoid stimulus	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligand	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
autosome genomic imprinting	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
regulation of mitophagy	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of amyloid-beta formation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of protein targeting to mitochondrion	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glycogen synthase activity, transferring glucose-1-phosphate	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of type B pancreatic cell development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glycogen (starch) synthase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of glycogen (starch) synthase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cell differentiation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
regulation of neuron projection development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of gene expression	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of gene expression	Glycogen synthase kinase-3 beta	Homo sapiens (human)
ER overload response	Glycogen synthase kinase-3 beta	Homo sapiens (human)
peptidyl-serine phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
intracellular signal transduction	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of apoptotic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein export from nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
epithelial to mesenchymal transition	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Glycogen synthase kinase-3 beta	Homo sapiens (human)
glycogen metabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
mitochondrion organization	Glycogen synthase kinase-3 beta	Homo sapiens (human)
dopamine receptor signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
circadian rhythm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of autophagy	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of gene expression	Glycogen synthase kinase-3 beta	Homo sapiens (human)
peptidyl-serine phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
peptidyl-threonine phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
viral protein processing	Glycogen synthase kinase-3 beta	Homo sapiens (human)
hippocampus development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
establishment of cell polarity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
maintenance of cell polarity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of cell migration	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of axon extension	Glycogen synthase kinase-3 beta	Homo sapiens (human)
neuron projection development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein-containing complex assembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein ubiquitination	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of phosphoprotein phosphatase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of microtubule-based process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
intracellular signal transduction	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cellular response to interleukin-3	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of circadian rhythm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of GTPase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of cell differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of osteoblast differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of glycogen biosynthetic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of cilium assembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein catabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein autophosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of protein export from nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of dendrite morphogenesis	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of axonogenesis	Glycogen synthase kinase-3 beta	Homo sapiens (human)
canonical Wnt signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
excitatory postsynaptic potential	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of calcineurin-NFAT signaling cascade	Glycogen synthase kinase-3 beta	Homo sapiens (human)
superior temporal gyrus development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cellular response to retinoic acid	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligand	Glycogen synthase kinase-3 beta	Homo sapiens (human)
presynaptic modulation of chemical synaptic transmission	Glycogen synthase kinase-3 beta	Homo sapiens (human)
neuron projection organization	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of microtubule anchoring at centrosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of cellular response to heat	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of protein localization to nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of long-term synaptic potentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of protein acetylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein localization to cilium	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of dopaminergic neuron differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cellular response to amyloid-beta	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein localization to centrosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
beta-catenin destruction complex disassembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of type B pancreatic cell development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of glycogen (starch) synthase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of mesenchymal stem cell differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of TOR signaling	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of neuron projection development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cell differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
insulin receptor signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription by RNA polymerase II	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription initiation at RNA polymerase II promoter	Cyclin-dependent kinase 7	Homo sapiens (human)
snRNA transcription by RNA polymerase II	Cyclin-dependent kinase 7	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 7	Homo sapiens (human)
protein stabilization	Cyclin-dependent kinase 7	Homo sapiens (human)
cell division	Cyclin-dependent kinase 7	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 7	Homo sapiens (human)
regulation of G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 7	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 7	Homo sapiens (human)
regulation of mitotic cell cycle	Cyclin-dependent kinase 9	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 9	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of DNA repair	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription initiation at RNA polymerase II promoter	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
cell population proliferation	Cyclin-dependent kinase 9	Homo sapiens (human)
replication fork processing	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of mRNA 3'-end processing	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation of transcription elongation by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation by host of viral transcription	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of muscle cell differentiation	Cyclin-dependent kinase 9	Homo sapiens (human)
nucleus localization	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 9	Homo sapiens (human)
cellular response to cytokine stimulus	Cyclin-dependent kinase 9	Homo sapiens (human)
negative regulation of protein localization to chromatin	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation of protein localization to chromatin	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation-coupled chromatin remodeling	Cyclin-dependent kinase 9	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 9	Homo sapiens (human)
exocytosis	Ras-related protein Rab-27A	Homo sapiens (human)
blood coagulation	Ras-related protein Rab-27A	Homo sapiens (human)
protein secretion	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of gene expression	Ras-related protein Rab-27A	Homo sapiens (human)
antigen processing and presentation	Ras-related protein Rab-27A	Homo sapiens (human)
melanocyte differentiation	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome localization	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome transport	Ras-related protein Rab-27A	Homo sapiens (human)
multivesicular body organization	Ras-related protein Rab-27A	Homo sapiens (human)
cytotoxic T cell degranulation	Ras-related protein Rab-27A	Homo sapiens (human)
natural killer cell degranulation	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of exocytosis	Ras-related protein Rab-27A	Homo sapiens (human)
synaptic vesicle transport	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of phagocytosis	Ras-related protein Rab-27A	Homo sapiens (human)
multivesicular body sorting pathway	Ras-related protein Rab-27A	Homo sapiens (human)
complement-dependent cytotoxicity	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of regulated secretory pathway	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of reactive oxygen species biosynthetic process	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of constitutive secretory pathway	Ras-related protein Rab-27A	Homo sapiens (human)
exosomal secretion	Ras-related protein Rab-27A	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Blk	Homo sapiens (human)
positive regulation of insulin secretion	Tyrosine-protein kinase Blk	Homo sapiens (human)
positive regulation of protein binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Blk	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Blk	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Blk	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Blk	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Blk	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Blk	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein autophosphorylation	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
regulation of cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
JNK cascade	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of type I interferon production	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor 2 signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor 9 signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cellular response to heat	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
interleukin-33-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein autophosphorylation	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
response to interleukin-1	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cellular response to hypoxia	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of leukocyte adhesion to vascular endothelial cell	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of MAP kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cellular response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
intracellular signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
Toll signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
innate immune response	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
gastrin-induced gastric acid secretion	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
glucose metabolic process	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
heart development	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
sensory perception of sound	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
rhythmic behavior	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of heart contraction	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of blood pressure	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
positive regulation of heart rate	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
iodide transport	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
erythrocyte differentiation	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
intracellular chloride ion homeostasis	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
response to insulin	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
social behavior	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
corticosterone secretion	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
inner ear morphogenesis	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
inner ear development	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
intestinal absorption	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of sound	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
potassium ion homeostasis	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cardiac muscle contraction	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
auditory receptor cell development	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of membrane repolarization	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane repolarization	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of atrial cardiac muscle cell membrane repolarization	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
positive regulation of cardiac muscle contraction	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of gastric acid secretion	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
stomach development	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
renal absorption	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
renal sodium ion absorption	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cellular response to cAMP	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cellular response to xenobiotic stimulus	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
potassium ion transmembrane transport	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cellular response to epinephrine stimulus	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
adrenergic receptor signaling pathway	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cardiac muscle cell contraction	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane repolarization during action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane repolarization during cardiac muscle cell action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
atrial cardiac muscle cell action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cochlea development	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane repolarization during atrial cardiac muscle cell action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane repolarization during ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
positive regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
non-motile cilium assembly	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
potassium ion import across plasma membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
action potential	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
skeletal system development	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
toll-like receptor signaling pathway	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
chemical synaptic transmission	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
central nervous system development	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
positive regulation of cell growth	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
response to lipopolysaccharide	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
negative regulation of apoptotic process	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
regulation of translation in response to stress	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
positive regulation of cell differentiation	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein phosphorylation	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
phosphatidylinositol biosynthetic process	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
apoptotic process	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
cell adhesion	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
signal transduction	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
mesoderm development	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
intracellular signal transduction	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
protein autophosphorylation	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
B cell receptor signaling pathway	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
adaptive immune response	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
angiogenesis	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
endothelial cell proliferation	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
cell adhesion	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
peptidyl-serine phosphorylation	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
myeloid cell differentiation	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
regulation of cell adhesion	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
regulation of cell migration	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
cell-substrate adhesion	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
endothelial cell migration	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
protein autophosphorylation	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
epithelial tube morphogenesis	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
kidney morphogenesis	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
regulation of epithelial cell differentiation involved in kidney development	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
blastocyst development	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
chromosome segregation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
regulation of mitotic nuclear division	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
regulation of mitotic centrosome separation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
spindle assembly	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
centrosome separation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
meiotic cell cycle	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
positive regulation of telomerase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
regulation of attachment of spindle microtubules to kinetochore	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
mitotic spindle assembly	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
negative regulation of centriole-centriole cohesion	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
positive regulation of telomere capping	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
neuron projection morphogenesis	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
regulation of tubulin deacetylation	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
regulation of cellular senescence	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of dendritic cell cytokine production	Tyrosine-protein kinase JAK3	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase JAK3	Homo sapiens (human)
enzyme-linked receptor protein signaling pathway	Tyrosine-protein kinase JAK3	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase JAK3	Homo sapiens (human)
B cell differentiation	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of interleukin-10 production	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of interleukin-12 production	Tyrosine-protein kinase JAK3	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase JAK3	Homo sapiens (human)
interleukin-15-mediated signaling pathway	Tyrosine-protein kinase JAK3	Homo sapiens (human)
interleukin-4-mediated signaling pathway	Tyrosine-protein kinase JAK3	Homo sapiens (human)
interleukin-2-mediated signaling pathway	Tyrosine-protein kinase JAK3	Homo sapiens (human)
interleukin-9-mediated signaling pathway	Tyrosine-protein kinase JAK3	Homo sapiens (human)
T cell homeostasis	Tyrosine-protein kinase JAK3	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of FasL production	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of T-helper 1 cell differentiation	Tyrosine-protein kinase JAK3	Homo sapiens (human)
regulation of receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of T cell activation	Tyrosine-protein kinase JAK3	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK3	Homo sapiens (human)
regulation of T cell apoptotic process	Tyrosine-protein kinase JAK3	Homo sapiens (human)
negative regulation of thymocyte apoptotic process	Tyrosine-protein kinase JAK3	Homo sapiens (human)
response to interleukin-2	Tyrosine-protein kinase JAK3	Homo sapiens (human)
response to interleukin-4	Tyrosine-protein kinase JAK3	Homo sapiens (human)
response to interleukin-15	Tyrosine-protein kinase JAK3	Homo sapiens (human)
response to interleukin-9	Tyrosine-protein kinase JAK3	Homo sapiens (human)
regulation of apoptotic process	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase JAK3	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
osteoblast differentiation	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of protein phosphorylation	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
response to ischemia	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
apoptotic process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
response to xenobiotic stimulus	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
ovulation cycle process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of prostaglandin secretion	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
p38MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
signal transduction in response to DNA damage	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of apoptotic process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
regulation of cell cycle	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cardiac muscle contraction	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
bone development	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cellular response to sorbitol	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
establishment of protein localization	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic sister chromatid segregation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
establishment of mitotic spindle orientation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic cytokinesis	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
microtubule bundle formation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
double-strand break repair	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic spindle organization	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
sister chromatid cohesion	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic chromosome condensation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic nuclear membrane disassembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
metaphase/anaphase transition of mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic spindle assembly checkpoint signaling	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centrosome cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
female meiosis chromosome segregation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein ubiquitination	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic metaphase/anaphase transition	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein destabilization	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of cytokinesis	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of protein binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
homologous chromosome segregation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of cyclin-dependent protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of proteolysis	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
Golgi inheritance	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nuclear membrane disassembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of ubiquitin-protein transferase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
synaptonemal complex disassembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein localization to chromatin	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein localization to nuclear envelope	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
double-strand break repair via alternative nonhomologous end joining	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic spindle assembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic cell cycle phase transition	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of ubiquitin protein ligase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of protein localization to cell cortex	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of anaphase-promoting complex-dependent catabolic process	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of double-strand break repair via homologous recombination	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
apoptotic process	Death-associated protein kinase 1	Homo sapiens (human)
defense response to tumor cell	Death-associated protein kinase 1	Homo sapiens (human)
regulation of response to tumor cell	Death-associated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Death-associated protein kinase 1	Homo sapiens (human)
apoptotic process	Death-associated protein kinase 1	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	Death-associated protein kinase 1	Homo sapiens (human)
regulation of autophagy	Death-associated protein kinase 1	Homo sapiens (human)
positive regulation of autophagy	Death-associated protein kinase 1	Homo sapiens (human)
negative regulation of translation	Death-associated protein kinase 1	Homo sapiens (human)
intracellular signal transduction	Death-associated protein kinase 1	Homo sapiens (human)
regulation of apoptotic process	Death-associated protein kinase 1	Homo sapiens (human)
positive regulation of apoptotic process	Death-associated protein kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Death-associated protein kinase 1	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Death-associated protein kinase 1	Homo sapiens (human)
protein autophosphorylation	Death-associated protein kinase 1	Homo sapiens (human)
cellular response to type II interferon	Death-associated protein kinase 1	Homo sapiens (human)
cellular response to hydroperoxide	Death-associated protein kinase 1	Homo sapiens (human)
apoptotic signaling pathway	Death-associated protein kinase 1	Homo sapiens (human)
positive regulation of autophagic cell death	Death-associated protein kinase 1	Homo sapiens (human)
regulation of NMDA receptor activity	Death-associated protein kinase 1	Homo sapiens (human)
protein phosphorylation	LIM domain kinase 1	Homo sapiens (human)
signal transduction	LIM domain kinase 1	Homo sapiens (human)
Rho protein signal transduction	LIM domain kinase 1	Homo sapiens (human)
nervous system development	LIM domain kinase 1	Homo sapiens (human)
positive regulation of actin filament bundle assembly	LIM domain kinase 1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	LIM domain kinase 1	Homo sapiens (human)
stress fiber assembly	LIM domain kinase 1	Homo sapiens (human)
positive regulation of axon extension	LIM domain kinase 1	Homo sapiens (human)
axon extension	LIM domain kinase 1	Homo sapiens (human)
negative regulation of ubiquitin-protein transferase activity	LIM domain kinase 1	Homo sapiens (human)
positive regulation of stress fiber assembly	LIM domain kinase 1	Homo sapiens (human)
actin cytoskeleton organization	LIM domain kinase 1	Homo sapiens (human)
positive regulation of protein phosphorylation	LIM domain kinase 2	Homo sapiens (human)
protein phosphorylation	LIM domain kinase 2	Homo sapiens (human)
spermatogenesis	LIM domain kinase 2	Homo sapiens (human)
phosphorylation	LIM domain kinase 2	Homo sapiens (human)
astral microtubule organization	LIM domain kinase 2	Homo sapiens (human)
establishment of vesicle localization	LIM domain kinase 2	Homo sapiens (human)
head development	LIM domain kinase 2	Homo sapiens (human)
cornea development in camera-type eye	LIM domain kinase 2	Homo sapiens (human)
positive regulation of protein localization to nucleus	LIM domain kinase 2	Homo sapiens (human)
negative regulation of cilium assembly	LIM domain kinase 2	Homo sapiens (human)
actin cytoskeleton organization	LIM domain kinase 2	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 12	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 12	Homo sapiens (human)
muscle organ development	Mitogen-activated protein kinase 12	Homo sapiens (human)
positive regulation of peptidase activity	Mitogen-activated protein kinase 12	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 12	Homo sapiens (human)
signal transduction in response to DNA damage	Mitogen-activated protein kinase 12	Homo sapiens (human)
myoblast differentiation	Mitogen-activated protein kinase 12	Homo sapiens (human)
negative regulation of cell cycle	Mitogen-activated protein kinase 12	Homo sapiens (human)
positive regulation of muscle cell differentiation	Mitogen-activated protein kinase 12	Homo sapiens (human)
regulation of cell cycle	Mitogen-activated protein kinase 12	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 12	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 10	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 10	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase 10	Homo sapiens (human)
response to light stimulus	Mitogen-activated protein kinase 10	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase 10	Homo sapiens (human)
regulation of circadian rhythm	Mitogen-activated protein kinase 10	Homo sapiens (human)
rhythmic process	Mitogen-activated protein kinase 10	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 10	Homo sapiens (human)
tyrosyl-tRNA aminoacylation	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
apoptotic process	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
response to starvation	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
regulation of glycolytic process	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
signal transduction	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
spermatogenesis	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
positive regulation of gene expression	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
positive regulation of protein kinase activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
import into nucleus	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
regulation of catalytic activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
lipid droplet disassembly	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
chromatin remodeling	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cholesterol biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
autophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
signal transduction	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
lipid biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
positive regulation of autophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
negative regulation of gene expression	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
response to muscle activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
Wnt signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
positive regulation of macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
regulation of macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
negative regulation of TOR signaling	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to oxidative stress	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to glucose starvation	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
glucose homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
regulation of circadian rhythm	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
negative regulation of apoptotic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
positive regulation of glycolytic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
rhythmic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
fatty acid homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
regulation of stress granule assembly	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to calcium ion	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to glucose stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to prostaglandin E stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cellular response to xenobiotic stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
energy homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
positive regulation of protein localization	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
negative regulation of hepatocyte apoptotic process	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
negative regulation of TORC1 signaling	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
negative regulation of tubulin deacetylation	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein localization to lipid droplet	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
positive regulation of peptidyl-lysine acetylation	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
urogenital system development	Ephrin type-B receptor 3	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 3	Homo sapiens (human)
axonal fasciculation	Ephrin type-B receptor 3	Homo sapiens (human)
cell migration	Ephrin type-B receptor 3	Homo sapiens (human)
central nervous system projection neuron axonogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
corpus callosum development	Ephrin type-B receptor 3	Homo sapiens (human)
regulation of cell-cell adhesion	Ephrin type-B receptor 3	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-B receptor 3	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Ephrin type-B receptor 3	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-B receptor 3	Homo sapiens (human)
protein autophosphorylation	Ephrin type-B receptor 3	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 3	Homo sapiens (human)
thymus development	Ephrin type-B receptor 3	Homo sapiens (human)
digestive tract morphogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
regulation of axonogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
positive regulation of synapse assembly	Ephrin type-B receptor 3	Homo sapiens (human)
roof of mouth development	Ephrin type-B receptor 3	Homo sapiens (human)
dendritic spine development	Ephrin type-B receptor 3	Homo sapiens (human)
dendritic spine morphogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 3	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 5	Homo sapiens (human)
cAMP-mediated signaling	Ephrin type-A receptor 5	Homo sapiens (human)
hippocampus development	Ephrin type-A receptor 5	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Ephrin type-A receptor 5	Homo sapiens (human)
regulation of actin cytoskeleton organization	Ephrin type-A receptor 5	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-A receptor 5	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 5	Homo sapiens (human)
neuron development	Ephrin type-A receptor 5	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Ephrin type-A receptor 5	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 5	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 4	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	Ephrin type-B receptor 4	Homo sapiens (human)
heart morphogenesis	Ephrin type-B receptor 4	Homo sapiens (human)
cell adhesion	Ephrin type-B receptor 4	Homo sapiens (human)
protein autophosphorylation	Ephrin type-B receptor 4	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 4	Homo sapiens (human)
multicellular organism development	Ephrin type-B receptor 4	Homo sapiens (human)
positive regulation of kinase activity	Ephrin type-B receptor 4	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 1	Homo sapiens (human)
immunological synapse formation	Ephrin type-B receptor 1	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 1	Homo sapiens (human)
skeletal muscle satellite cell activation	Ephrin type-B receptor 1	Homo sapiens (human)
optic nerve morphogenesis	Ephrin type-B receptor 1	Homo sapiens (human)
hindbrain tangential cell migration	Ephrin type-B receptor 1	Homo sapiens (human)
central nervous system projection neuron axonogenesis	Ephrin type-B receptor 1	Homo sapiens (human)
neurogenesis	Ephrin type-B receptor 1	Homo sapiens (human)
establishment of cell polarity	Ephrin type-B receptor 1	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-B receptor 1	Homo sapiens (human)
cell-substrate adhesion	Ephrin type-B receptor 1	Homo sapiens (human)
regulation of JNK cascade	Ephrin type-B receptor 1	Homo sapiens (human)
protein autophosphorylation	Ephrin type-B receptor 1	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 1	Homo sapiens (human)
camera-type eye morphogenesis	Ephrin type-B receptor 1	Homo sapiens (human)
modulation of chemical synaptic transmission	Ephrin type-B receptor 1	Homo sapiens (human)
detection of temperature stimulus involved in sensory perception of pain	Ephrin type-B receptor 1	Homo sapiens (human)
positive regulation of synapse assembly	Ephrin type-B receptor 1	Homo sapiens (human)
cell chemotaxis	Ephrin type-B receptor 1	Homo sapiens (human)
dendritic spine development	Ephrin type-B receptor 1	Homo sapiens (human)
dendritic spine morphogenesis	Ephrin type-B receptor 1	Homo sapiens (human)
neural precursor cell proliferation	Ephrin type-B receptor 1	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Ephrin type-B receptor 1	Homo sapiens (human)
negative regulation of skeletal muscle satellite cell proliferation	Ephrin type-B receptor 1	Homo sapiens (human)
negative regulation of satellite cell differentiation	Ephrin type-B receptor 1	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 1	Homo sapiens (human)
negative regulation of cellular response to hypoxia	Ephrin type-A receptor 4	Homo sapiens (human)
cell adhesion	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of cell adhesion	Ephrin type-A receptor 4	Homo sapiens (human)
adult walking behavior	Ephrin type-A receptor 4	Homo sapiens (human)
motor neuron axon guidance	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of cell population proliferation	Ephrin type-A receptor 4	Homo sapiens (human)
glial cell migration	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of epithelial to mesenchymal transition	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of neuron projection development	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of translation	Ephrin type-A receptor 4	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Ephrin type-A receptor 4	Homo sapiens (human)
corticospinal tract morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of cell migration	Ephrin type-A receptor 4	Homo sapiens (human)
adherens junction organization	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of cell adhesion	Ephrin type-A receptor 4	Homo sapiens (human)
protein autophosphorylation	Ephrin type-A receptor 4	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of axon regeneration	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of astrocyte differentiation	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of axonogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of dendrite morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
protein stabilization	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of dendritic spine morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of protein tyrosine kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Ephrin type-A receptor 4	Homo sapiens (human)
nephric duct morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
cochlea development	Ephrin type-A receptor 4	Homo sapiens (human)
fasciculation of sensory neuron axon	Ephrin type-A receptor 4	Homo sapiens (human)
fasciculation of motor neuron axon	Ephrin type-A receptor 4	Homo sapiens (human)
neuron projection guidance	Ephrin type-A receptor 4	Homo sapiens (human)
synapse pruning	Ephrin type-A receptor 4	Homo sapiens (human)
neuron projection fasciculation	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of long-term synaptic potentiation	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of amyloid-beta formation	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of proteolysis involved in protein catabolic process	Ephrin type-A receptor 4	Homo sapiens (human)
cellular response to amyloid-beta	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of modification of synaptic structure	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of synapse pruning	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of Rho guanyl-nucleotide exchange factor activity	Ephrin type-A receptor 4	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 4	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 4	Homo sapiens (human)
ADP biosynthetic process	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
nucleobase-containing small molecule interconversion	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
AMP metabolic process	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
ATP metabolic process	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
nucleoside monophosphate phosphorylation	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
purine ribonucleoside salvage	Adenosine kinase	Homo sapiens (human)
dATP biosynthetic process	Adenosine kinase	Homo sapiens (human)
ribonucleoside monophosphate biosynthetic process	Adenosine kinase	Homo sapiens (human)
GMP salvage	Adenosine kinase	Homo sapiens (human)
AMP salvage	Adenosine kinase	Homo sapiens (human)
dAMP salvage	Adenosine kinase	Homo sapiens (human)
purine nucleobase metabolic process	Adenosine kinase	Homo sapiens (human)
signal transduction	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
intracellular signal transduction	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
regulation of sodium ion transport	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
regulation of myotube differentiation	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
negative regulation of triglyceride biosynthetic process	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
negative regulation of CREB transcription factor activity	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
entrainment of circadian clock by photoperiod	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
anoikis	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
regulation of cell differentiation	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
negative regulation of gluconeogenesis	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
rhythmic process	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
cardiac muscle cell differentiation	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
positive regulation of anoikis	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
morphogenesis of an epithelium	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
Golgi to plasma membrane transport	Ras-related protein Rab-10	Homo sapiens (human)
axonogenesis	Ras-related protein Rab-10	Homo sapiens (human)
vesicle-mediated transport	Ras-related protein Rab-10	Homo sapiens (human)
endosomal transport	Ras-related protein Rab-10	Homo sapiens (human)
antigen processing and presentation	Ras-related protein Rab-10	Homo sapiens (human)
polarized epithelial cell differentiation	Ras-related protein Rab-10	Homo sapiens (human)
cellular response to insulin stimulus	Ras-related protein Rab-10	Homo sapiens (human)
Golgi to plasma membrane protein transport	Ras-related protein Rab-10	Homo sapiens (human)
regulated exocytosis	Ras-related protein Rab-10	Homo sapiens (human)
establishment of neuroblast polarity	Ras-related protein Rab-10	Homo sapiens (human)
endoplasmic reticulum tubular network organization	Ras-related protein Rab-10	Homo sapiens (human)
protein localization to plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
establishment of protein localization to membrane	Ras-related protein Rab-10	Homo sapiens (human)
establishment of protein localization to endoplasmic reticulum membrane	Ras-related protein Rab-10	Homo sapiens (human)
cell-cell adhesion	Ras-related protein Rab-10	Homo sapiens (human)
protein localization to basolateral plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
exocytosis	Ras-related protein Rab-10	Homo sapiens (human)
protein secretion	Ras-related protein Rab-10	Homo sapiens (human)
establishment or maintenance of cell polarity	Actin-related protein 3	Homo sapiens (human)
asymmetric cell division	Actin-related protein 3	Homo sapiens (human)
positive regulation of lamellipodium assembly	Actin-related protein 3	Homo sapiens (human)
meiotic chromosome movement towards spindle pole	Actin-related protein 3	Homo sapiens (human)
meiotic cytokinesis	Actin-related protein 3	Homo sapiens (human)
Arp2/3 complex-mediated actin nucleation	Actin-related protein 3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Actin-related protein 3	Homo sapiens (human)
spindle localization	Actin-related protein 3	Homo sapiens (human)
cilium assembly	Actin-related protein 3	Homo sapiens (human)
actin polymerization-dependent cell motility	Actin-related protein 3	Homo sapiens (human)
cellular response to type II interferon	Actin-related protein 3	Homo sapiens (human)
regulation of double-strand break repair via nonhomologous end joining	Actin-related protein 2	Homo sapiens (human)
cilium assembly	Actin-related protein 2	Homo sapiens (human)
establishment or maintenance of cell polarity	Actin-related protein 2	Homo sapiens (human)
asymmetric cell division	Actin-related protein 2	Homo sapiens (human)
positive regulation of lamellipodium assembly	Actin-related protein 2	Homo sapiens (human)
meiotic chromosome movement towards spindle pole	Actin-related protein 2	Homo sapiens (human)
cytosolic transport	Actin-related protein 2	Homo sapiens (human)
meiotic cytokinesis	Actin-related protein 2	Homo sapiens (human)
Arp2/3 complex-mediated actin nucleation	Actin-related protein 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Actin-related protein 2	Homo sapiens (human)
spindle localization	Actin-related protein 2	Homo sapiens (human)
cellular response to type II interferon	Actin-related protein 2	Homo sapiens (human)
positive regulation of double-strand break repair via homologous recombination	Actin-related protein 2	Homo sapiens (human)
ribosomal large subunit export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
ribosomal small subunit export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
mitotic sister chromatid segregation	GTP-binding nuclear protein Ran	Homo sapiens (human)
mitotic cell cycle	GTP-binding nuclear protein Ran	Homo sapiens (human)
DNA metabolic process	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein import into nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
mitotic spindle organization	GTP-binding nuclear protein Ran	Homo sapiens (human)
spermatid development	GTP-binding nuclear protein Ran	Homo sapiens (human)
viral process	GTP-binding nuclear protein Ran	Homo sapiens (human)
hippocampus development	GTP-binding nuclear protein Ran	Homo sapiens (human)
actin cytoskeleton organization	GTP-binding nuclear protein Ran	Homo sapiens (human)
positive regulation of protein binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
pre-miRNA export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
positive regulation of protein import into nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTP metabolic process	GTP-binding nuclear protein Ran	Homo sapiens (human)
cell division	GTP-binding nuclear protein Ran	Homo sapiens (human)
snRNA import into nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
cellular response to mineralocorticoid stimulus	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein localization to nucleolus	GTP-binding nuclear protein Ran	Homo sapiens (human)
ribosomal subunit export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
positive regulation of lamellipodium assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
actin cytoskeleton organization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
ruffle organization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
neuron migration	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of protein phosphorylation	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
sphingosine-1-phosphate receptor signaling pathway	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
inflammatory response	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell adhesion	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell-matrix adhesion	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
small GTPase-mediated signal transduction	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of cell size	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
response to wounding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
anatomical structure morphogenesis	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of hydrogen peroxide metabolic process	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of lamellipodium assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of lamellipodium assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of endothelial cell migration	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
negative regulation of fibroblast migration	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of cell-substrate adhesion	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell migration	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
lamellipodium assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
actin filament polymerization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of cell migration	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of microtubule polymerization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
ruffle organization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
negative regulation of interleukin-23 production	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
intracellular signal transduction	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of nitric oxide biosynthetic process	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
respiratory burst	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
hepatocyte growth factor receptor signaling pathway	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
negative regulation of receptor-mediated endocytosis	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell motility	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of stress fiber assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of stress fiber assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
localization within membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of focal adhesion assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
Wnt signaling pathway, planar cell polarity pathway	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of respiratory burst	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
semaphorin-plexin signaling pathway	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of neutrophil chemotaxis	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
ruffle assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
engulfment of apoptotic cell	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell projection assembly	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cortical cytoskeleton organization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of neutrophil migration	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
establishment or maintenance of cell polarity	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of cell shape	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
Rac protein signal transduction	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
actin filament organization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell chemotaxis	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
motor neuron axon guidance	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
double-strand break repair	Casein kinase II subunit alpha	Homo sapiens (human)
protein phosphorylation	Casein kinase II subunit alpha	Homo sapiens (human)
apoptotic process	Casein kinase II subunit alpha	Homo sapiens (human)
DNA damage response	Casein kinase II subunit alpha	Homo sapiens (human)
signal transduction	Casein kinase II subunit alpha	Homo sapiens (human)
positive regulation of cell population proliferation	Casein kinase II subunit alpha	Homo sapiens (human)
Wnt signaling pathway	Casein kinase II subunit alpha	Homo sapiens (human)
negative regulation of translation	Casein kinase II subunit alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase II subunit alpha	Homo sapiens (human)
peptidyl-threonine phosphorylation	Casein kinase II subunit alpha	Homo sapiens (human)
positive regulation of Wnt signaling pathway	Casein kinase II subunit alpha	Homo sapiens (human)
positive regulation of cell growth	Casein kinase II subunit alpha	Homo sapiens (human)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase II subunit alpha	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Casein kinase II subunit alpha	Homo sapiens (human)
positive regulation of protein catabolic process	Casein kinase II subunit alpha	Homo sapiens (human)
rhythmic process	Casein kinase II subunit alpha	Homo sapiens (human)
protein stabilization	Casein kinase II subunit alpha	Homo sapiens (human)
chaperone-mediated protein folding	Casein kinase II subunit alpha	Homo sapiens (human)
symbiont-mediated disruption of host cell PML body	Casein kinase II subunit alpha	Homo sapiens (human)
positive regulation of aggrephagy	Casein kinase II subunit alpha	Homo sapiens (human)
regulation of chromosome separation	Casein kinase II subunit alpha	Homo sapiens (human)
negative regulation of double-strand break repair via homologous recombination	Casein kinase II subunit alpha	Homo sapiens (human)
negative regulation of apoptotic signaling pathway	Casein kinase II subunit alpha	Homo sapiens (human)
regulation of cell cycle	Casein kinase II subunit alpha	Homo sapiens (human)
cell surface receptor signaling pathway	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
regulation of autophagy	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
autophagosome-lysosome fusion	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
positive regulation of autophagosome assembly	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
spliceosomal complex assembly	SRSF protein kinase 2	Homo sapiens (human)
angiogenesis	SRSF protein kinase 2	Homo sapiens (human)
protein phosphorylation	SRSF protein kinase 2	Homo sapiens (human)
positive regulation of cell population proliferation	SRSF protein kinase 2	Homo sapiens (human)
RNA splicing	SRSF protein kinase 2	Homo sapiens (human)
positive regulation of gene expression	SRSF protein kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	SRSF protein kinase 2	Homo sapiens (human)
cell differentiation	SRSF protein kinase 2	Homo sapiens (human)
nuclear speck organization	SRSF protein kinase 2	Homo sapiens (human)
intracellular signal transduction	SRSF protein kinase 2	Homo sapiens (human)
positive regulation of neuron apoptotic process	SRSF protein kinase 2	Homo sapiens (human)
positive regulation of viral genome replication	SRSF protein kinase 2	Homo sapiens (human)
negative regulation of viral genome replication	SRSF protein kinase 2	Homo sapiens (human)
innate immune response	SRSF protein kinase 2	Homo sapiens (human)
positive regulation of cell cycle	SRSF protein kinase 2	Homo sapiens (human)
regulation of mRNA splicing, via spliceosome	SRSF protein kinase 2	Homo sapiens (human)
R-loop processing	SRSF protein kinase 2	Homo sapiens (human)
regulation of mRNA processing	SRSF protein kinase 2	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform gamma-2	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform gamma-2	Homo sapiens (human)
sphingolipid biosynthetic process	Casein kinase I isoform gamma-2	Homo sapiens (human)
signal transduction	Casein kinase I isoform gamma-2	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform gamma-2	Homo sapiens (human)
endocytosis	Casein kinase I isoform gamma-2	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform gamma-2	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
DNA damage response	Cyclin-dependent kinase 3	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 3	Homo sapiens (human)
cell population proliferation	Cyclin-dependent kinase 3	Homo sapiens (human)
G0 to G1 transition	Cyclin-dependent kinase 3	Homo sapiens (human)
negative regulation of Notch signaling pathway	Cyclin-dependent kinase 3	Homo sapiens (human)
cell division	Cyclin-dependent kinase 3	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 3	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 3	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 3	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 3	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 3	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase-like 1	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase-like 1	Homo sapiens (human)
regulation of cilium assembly	Cyclin-dependent kinase-like 1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 6	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Cyclin-dependent kinase 6	Homo sapiens (human)
type B pancreatic cell development	Cyclin-dependent kinase 6	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 6	Homo sapiens (human)
Notch signaling pathway	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cell population proliferation	Cyclin-dependent kinase 6	Homo sapiens (human)
response to virus	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 6	Homo sapiens (human)
positive regulation of gene expression	Cyclin-dependent kinase 6	Homo sapiens (human)
astrocyte development	Cyclin-dependent kinase 6	Homo sapiens (human)
dentate gyrus development	Cyclin-dependent kinase 6	Homo sapiens (human)
lateral ventricle development	Cyclin-dependent kinase 6	Homo sapiens (human)
T cell differentiation in thymus	Cyclin-dependent kinase 6	Homo sapiens (human)
gliogenesis	Cyclin-dependent kinase 6	Homo sapiens (human)
cell dedifferentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of myeloid cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of erythrocyte differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of monocyte differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of osteoblast differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
positive regulation of fibroblast proliferation	Cyclin-dependent kinase 6	Homo sapiens (human)
generation of neurons	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of epithelial cell proliferation	Cyclin-dependent kinase 6	Homo sapiens (human)
cell division	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
hematopoietic stem cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of hematopoietic stem cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of cell motility	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cellular senescence	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 6	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 6	Homo sapiens (human)
microtubule cytoskeleton organization	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron migration	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic transmission, dopaminergic	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
intracellular protein transport	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cell-matrix adhesion	Cyclin-dependent-like kinase 5	Homo sapiens (human)
chemical synaptic transmission	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synapse assembly	Cyclin-dependent-like kinase 5	Homo sapiens (human)
skeletal muscle tissue development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
motor neuron axon guidance	Cyclin-dependent-like kinase 5	Homo sapiens (human)
visual learning	Cyclin-dependent-like kinase 5	Homo sapiens (human)
Schwann cell development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle exocytosis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of macroautophagy	Cyclin-dependent-like kinase 5	Homo sapiens (human)
phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
peptidyl-threonine phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
sensory perception of pain	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cerebellar cortex formation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
hippocampus development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
layer formation in cerebral cortex	Cyclin-dependent-like kinase 5	Homo sapiens (human)
central nervous system neuron development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
corpus callosum development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron differentiation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of cell migration	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of axon extension	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron projection development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of protein ubiquitination	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of synaptic plasticity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
receptor catabolic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic transmission, glutamatergic	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein localization to synapse	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of apoptotic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
receptor clustering	Cyclin-dependent-like kinase 5	Homo sapiens (human)
positive regulation of neuron apoptotic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of cell cycle	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of proteolysis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of DNA-templated transcription	Cyclin-dependent-like kinase 5	Homo sapiens (human)
positive regulation of calcium ion-dependent exocytosis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of protein export from nucleus	Cyclin-dependent-like kinase 5	Homo sapiens (human)
behavioral response to cocaine	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of synaptic plasticity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle endocytosis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
rhythmic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
axon extension	Cyclin-dependent-like kinase 5	Homo sapiens (human)
oligodendrocyte differentiation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
dendrite morphogenesis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cell division	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron apoptotic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of synaptic transmission, glutamatergic	Cyclin-dependent-like kinase 5	Homo sapiens (human)
excitatory postsynaptic potential	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of dendritic spine morphogenesis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
calcium ion import	Cyclin-dependent-like kinase 5	Homo sapiens (human)
positive regulation of protein targeting to membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of protein localization to plasma membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of synaptic vesicle recycling	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cellular response to amyloid-beta	Cyclin-dependent-like kinase 5	Homo sapiens (human)
axonogenesis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle transport	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 16	Homo sapiens (human)
exocytosis	Cyclin-dependent kinase 16	Homo sapiens (human)
spermatogenesis	Cyclin-dependent kinase 16	Homo sapiens (human)
positive regulation of autophagy	Cyclin-dependent kinase 16	Homo sapiens (human)
growth hormone secretion	Cyclin-dependent kinase 16	Homo sapiens (human)
neuron projection development	Cyclin-dependent kinase 16	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 16	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Cyclin-dependent kinase 16	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 17	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 17	Homo sapiens (human)
calcium ion transport	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
sensory perception of sound	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
positive regulation of adenylate cyclase activity	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
positive regulation of calcium ion transport	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
regulation of atrial cardiac muscle cell membrane repolarization	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
calcium ion import	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
calcium ion transmembrane transport	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
cardiac muscle cell action potential involved in contraction	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
membrane depolarization during cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
membrane depolarization during SA node cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
regulation of potassium ion transmembrane transporter activity	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
regulation of potassium ion transmembrane transport	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
calcium ion import across plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
cellular response to leukemia inhibitory factor	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
canonical glycolysis	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
fructose 1,6-bisphosphate metabolic process	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
fructose 6-phosphate metabolic process	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
MAPK cascade	Protein kinase C epsilon type	Homo sapiens (human)
macrophage activation involved in immune response	Protein kinase C epsilon type	Homo sapiens (human)
protein phosphorylation	Protein kinase C epsilon type	Homo sapiens (human)
apoptotic process	Protein kinase C epsilon type	Homo sapiens (human)
signal transduction	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of epithelial cell migration	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of fibroblast migration	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of cell-substrate adhesion	Protein kinase C epsilon type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C epsilon type	Homo sapiens (human)
insulin secretion	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of actin filament polymerization	Protein kinase C epsilon type	Homo sapiens (human)
negative regulation of protein ubiquitination	Protein kinase C epsilon type	Homo sapiens (human)
cell-substrate adhesion	Protein kinase C epsilon type	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of synaptic transmission, GABAergic	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of cytokinesis	Protein kinase C epsilon type	Homo sapiens (human)
locomotory exploration behavior	Protein kinase C epsilon type	Homo sapiens (human)
TRAM-dependent toll-like receptor 4 signaling pathway	Protein kinase C epsilon type	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Protein kinase C epsilon type	Homo sapiens (human)
response to morphine	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of MAPK cascade	Protein kinase C epsilon type	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of lipid catabolic process	Protein kinase C epsilon type	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Protein kinase C epsilon type	Homo sapiens (human)
cell division	Protein kinase C epsilon type	Homo sapiens (human)
establishment of localization in cell	Protein kinase C epsilon type	Homo sapiens (human)
synaptic transmission, GABAergic	Protein kinase C epsilon type	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Protein kinase C epsilon type	Homo sapiens (human)
mucus secretion	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of mucus secretion	Protein kinase C epsilon type	Homo sapiens (human)
cellular response to ethanol	Protein kinase C epsilon type	Homo sapiens (human)
cellular response to prostaglandin E stimulus	Protein kinase C epsilon type	Homo sapiens (human)
cellular response to hypoxia	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of wound healing	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C epsilon type	Homo sapiens (human)
negative regulation of sodium ion transmembrane transporter activity	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of cellular glucuronidation	Protein kinase C epsilon type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C epsilon type	Homo sapiens (human)
chemotaxis	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
negative regulation of cell population proliferation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of gene expression	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
Schwann cell development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cerebellar cortex formation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
keratinocyte differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
thyroid gland development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
endodermal cell differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
myelination	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
type B pancreatic cell proliferation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
thymus development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of axon regeneration	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cell motility	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of axonogenesis	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
Bergmann glial cell differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
face development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
trachea formation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
epithelial cell proliferation involved in lung morphogenesis	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
placenta blood vessel development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
labyrinthine layer development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of Golgi inheritance	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of endodermal cell differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of early endosome to late endosome transport	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
neuron differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Angiopoietin-1 receptor	Homo sapiens (human)
angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
response to hypoxia	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Angiopoietin-1 receptor	Homo sapiens (human)
endothelial cell proliferation	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Angiopoietin-1 receptor	Homo sapiens (human)
endochondral ossification	Angiopoietin-1 receptor	Homo sapiens (human)
sprouting angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Angiopoietin-1 receptor	Homo sapiens (human)
cell-cell signaling	Angiopoietin-1 receptor	Homo sapiens (human)
heart development	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of endothelial cell migration	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of establishment or maintenance of cell polarity	Angiopoietin-1 receptor	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of Rac protein signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of vascular permeability	Angiopoietin-1 receptor	Homo sapiens (human)
response to peptide hormone	Angiopoietin-1 receptor	Homo sapiens (human)
response to estrogen	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
Tie signaling pathway	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of inflammatory response	Angiopoietin-1 receptor	Homo sapiens (human)
response to cAMP	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of focal adhesion assembly	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
definitive hemopoiesis	Angiopoietin-1 receptor	Homo sapiens (human)
heart trabecula formation	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Angiopoietin-1 receptor	Homo sapiens (human)
glomerulus vasculature development	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of intracellular signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of endothelial cell apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
multicellular organism development	Angiopoietin-1 receptor	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
smoothened signaling pathway	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
peptidyl-threonine phosphorylation	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
negative regulation of DNA-binding transcription factor activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
negative regulation of DNA-templated transcription	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
neuron migration	DNA topoisomerase 2-beta	Homo sapiens (human)
DNA topological change	DNA topoisomerase 2-beta	Homo sapiens (human)
axonogenesis	DNA topoisomerase 2-beta	Homo sapiens (human)
B cell differentiation	DNA topoisomerase 2-beta	Homo sapiens (human)
forebrain development	DNA topoisomerase 2-beta	Homo sapiens (human)
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	DNA topoisomerase 2-beta	Homo sapiens (human)
cellular response to hydrogen peroxide	DNA topoisomerase 2-beta	Homo sapiens (human)
cellular response to ATP	DNA topoisomerase 2-beta	Homo sapiens (human)
cellular senescence	DNA topoisomerase 2-beta	Homo sapiens (human)
positive regulation of double-strand break repair via nonhomologous end joining	DNA topoisomerase 2-beta	Homo sapiens (human)
sister chromatid segregation	DNA topoisomerase 2-beta	Homo sapiens (human)
resolution of meiotic recombination intermediates	DNA topoisomerase 2-beta	Homo sapiens (human)
regulation of cell growth	Protein kinase C theta type	Homo sapiens (human)
regulation of DNA-templated transcription	Protein kinase C theta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C theta type	Homo sapiens (human)
membrane protein ectodomain proteolysis	Protein kinase C theta type	Homo sapiens (human)
inflammatory response	Protein kinase C theta type	Homo sapiens (human)
axon guidance	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-17 production	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-2 production	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-4 production	Protein kinase C theta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C theta type	Homo sapiens (human)
CD4-positive, alpha-beta T cell proliferation	Protein kinase C theta type	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Protein kinase C theta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T cell activation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomerase activity	Protein kinase C theta type	Homo sapiens (human)
cell chemotaxis	Protein kinase C theta type	Homo sapiens (human)
negative regulation of T cell apoptotic process	Protein kinase C theta type	Homo sapiens (human)
regulation of platelet aggregation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomere capping	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Protein kinase C theta type	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T-helper 2 cell activation	Protein kinase C theta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C theta type	Homo sapiens (human)
outflow tract septum morphogenesis	Activin receptor type-1	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Activin receptor type-1	Homo sapiens (human)
in utero embryonic development	Activin receptor type-1	Homo sapiens (human)
gastrulation with mouth forming second	Activin receptor type-1	Homo sapiens (human)
mesoderm formation	Activin receptor type-1	Homo sapiens (human)
neural crest cell migration	Activin receptor type-1	Homo sapiens (human)
acute inflammatory response	Activin receptor type-1	Homo sapiens (human)
embryonic heart tube morphogenesis	Activin receptor type-1	Homo sapiens (human)
atrioventricular valve morphogenesis	Activin receptor type-1	Homo sapiens (human)
mitral valve morphogenesis	Activin receptor type-1	Homo sapiens (human)
endocardial cushion formation	Activin receptor type-1	Homo sapiens (human)
endocardial cushion fusion	Activin receptor type-1	Homo sapiens (human)
atrial septum primum morphogenesis	Activin receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Activin receptor type-1	Homo sapiens (human)
germ cell development	Activin receptor type-1	Homo sapiens (human)
determination of left/right symmetry	Activin receptor type-1	Homo sapiens (human)
negative regulation of signal transduction	Activin receptor type-1	Homo sapiens (human)
regulation of ossification	Activin receptor type-1	Homo sapiens (human)
positive regulation of cell migration	Activin receptor type-1	Homo sapiens (human)
positive regulation of bone mineralization	Activin receptor type-1	Homo sapiens (human)
BMP signaling pathway	Activin receptor type-1	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-1	Homo sapiens (human)
negative regulation of activin receptor signaling pathway	Activin receptor type-1	Homo sapiens (human)
positive regulation of osteoblast differentiation	Activin receptor type-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Activin receptor type-1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Activin receptor type-1	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Activin receptor type-1	Homo sapiens (human)
smooth muscle cell differentiation	Activin receptor type-1	Homo sapiens (human)
pharyngeal system development	Activin receptor type-1	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Activin receptor type-1	Homo sapiens (human)
ventricular septum morphogenesis	Activin receptor type-1	Homo sapiens (human)
cardiac muscle cell fate commitment	Activin receptor type-1	Homo sapiens (human)
endocardial cushion cell fate commitment	Activin receptor type-1	Homo sapiens (human)
positive regulation of cardiac epithelial to mesenchymal transition	Activin receptor type-1	Homo sapiens (human)
cellular response to BMP stimulus	Activin receptor type-1	Homo sapiens (human)
positive regulation of determination of dorsal identity	Activin receptor type-1	Homo sapiens (human)
negative regulation of G1/S transition of mitotic cell cycle	Activin receptor type-1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Activin receptor type-1	Homo sapiens (human)
dorsal/ventral pattern formation	Activin receptor type-1	Homo sapiens (human)
heart development	Activin receptor type-1	Homo sapiens (human)
protein phosphorylation	Activin receptor type-1	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-1	Homo sapiens (human)
defense response	Macrophage-stimulating protein receptor	Homo sapiens (human)
signal transduction	Macrophage-stimulating protein receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Macrophage-stimulating protein receptor	Homo sapiens (human)
single fertilization	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Macrophage-stimulating protein receptor	Homo sapiens (human)
response to virus	Macrophage-stimulating protein receptor	Homo sapiens (human)
macrophage colony-stimulating factor signaling pathway	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of MAP kinase activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
innate immune response	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Macrophage-stimulating protein receptor	Homo sapiens (human)
nervous system development	Macrophage-stimulating protein receptor	Homo sapiens (human)
cell migration	Macrophage-stimulating protein receptor	Homo sapiens (human)
phagocytosis	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of kinase activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
multicellular organism development	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of macrophage proliferation	Focal adhesion kinase 1	Homo sapiens (human)
angiogenesis	Focal adhesion kinase 1	Homo sapiens (human)
placenta development	Focal adhesion kinase 1	Homo sapiens (human)
regulation of protein phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of protein phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
heart morphogenesis	Focal adhesion kinase 1	Homo sapiens (human)
signal complex assembly	Focal adhesion kinase 1	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
integrin-mediated signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
axon guidance	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of cell population proliferation	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell shape	Focal adhesion kinase 1	Homo sapiens (human)
regulation of endothelial cell migration	Focal adhesion kinase 1	Homo sapiens (human)
regulation of epithelial cell migration	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of epithelial cell migration	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of fibroblast migration	Focal adhesion kinase 1	Homo sapiens (human)
cell migration	Focal adhesion kinase 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
negative regulation of cell-cell adhesion	Focal adhesion kinase 1	Homo sapiens (human)
establishment of cell polarity	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of cell migration	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Focal adhesion kinase 1	Homo sapiens (human)
detection of muscle stretch	Focal adhesion kinase 1	Homo sapiens (human)
netrin-activated signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell population proliferation	Focal adhesion kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Focal adhesion kinase 1	Homo sapiens (human)
regulation of GTPase activity	Focal adhesion kinase 1	Homo sapiens (human)
regulation of osteoblast differentiation	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of protein kinase activity	Focal adhesion kinase 1	Homo sapiens (human)
protein autophosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
ephrin receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
cell motility	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cytoskeleton organization	Focal adhesion kinase 1	Homo sapiens (human)
regulation of focal adhesion assembly	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Focal adhesion kinase 1	Homo sapiens (human)
growth hormone receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of wound healing	Focal adhesion kinase 1	Homo sapiens (human)
regulation of substrate adhesion-dependent cell spreading	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of ubiquitin-dependent protein catabolic process	Focal adhesion kinase 1	Homo sapiens (human)
negative regulation of anoikis	Focal adhesion kinase 1	Homo sapiens (human)
protein phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell adhesion	Focal adhesion kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Protein kinase C zeta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
inflammatory response	Protein kinase C zeta type	Homo sapiens (human)
signal transduction	Protein kinase C zeta type	Homo sapiens (human)
cell surface receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
long-term memory	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of cell population proliferation	Protein kinase C zeta type	Homo sapiens (human)
cell migration	Protein kinase C zeta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
establishment of cell polarity	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-10 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-13 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-4 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-5 production	Protein kinase C zeta type	Homo sapiens (human)
cellular response to insulin stimulus	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of apoptotic process	Protein kinase C zeta type	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of T-helper 2 cell differentiation	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
vesicle transport along microtubule	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of peptidyl-tyrosine phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of protein transport	Protein kinase C zeta type	Homo sapiens (human)
membrane depolarization	Protein kinase C zeta type	Homo sapiens (human)
membrane hyperpolarization	Protein kinase C zeta type	Homo sapiens (human)
long-term synaptic potentiation	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein kinase C zeta type	Homo sapiens (human)
protein kinase C signaling	Protein kinase C zeta type	Homo sapiens (human)
protein localization to plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Protein kinase C zeta type	Homo sapiens (human)
neuron projection extension	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of excitatory postsynaptic potential	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of T-helper 2 cell cytokine production	Protein kinase C zeta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C zeta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C delta type	Homo sapiens (human)
apoptotic process	Protein kinase C delta type	Homo sapiens (human)
DNA damage response	Protein kinase C delta type	Homo sapiens (human)
signal transduction	Protein kinase C delta type	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Protein kinase C delta type	Homo sapiens (human)
regulation of signaling receptor activity	Protein kinase C delta type	Homo sapiens (human)
immunoglobulin mediated immune response	Protein kinase C delta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
termination of signal transduction	Protein kinase C delta type	Homo sapiens (human)
negative regulation of actin filament polymerization	Protein kinase C delta type	Homo sapiens (human)
positive regulation of endodeoxyribonuclease activity	Protein kinase C delta type	Homo sapiens (human)
negative regulation of protein binding	Protein kinase C delta type	Homo sapiens (human)
activation of protein kinase activity	Protein kinase C delta type	Homo sapiens (human)
positive regulation of superoxide anion generation	Protein kinase C delta type	Homo sapiens (human)
regulation of actin cytoskeleton organization	Protein kinase C delta type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C delta type	Homo sapiens (human)
cellular response to UV	Protein kinase C delta type	Homo sapiens (human)
positive regulation of protein dephosphorylation	Protein kinase C delta type	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Protein kinase C delta type	Homo sapiens (human)
B cell proliferation	Protein kinase C delta type	Homo sapiens (human)
neutrophil activation	Protein kinase C delta type	Homo sapiens (human)
positive regulation of protein import into nucleus	Protein kinase C delta type	Homo sapiens (human)
defense response to bacterium	Protein kinase C delta type	Homo sapiens (human)
negative regulation of MAP kinase activity	Protein kinase C delta type	Homo sapiens (human)
regulation of mRNA stability	Protein kinase C delta type	Homo sapiens (human)
post-translational protein modification	Protein kinase C delta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C delta type	Homo sapiens (human)
negative regulation of inflammatory response	Protein kinase C delta type	Homo sapiens (human)
negative regulation of peptidyl-tyrosine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
protein stabilization	Protein kinase C delta type	Homo sapiens (human)
negative regulation of filopodium assembly	Protein kinase C delta type	Homo sapiens (human)
cell chemotaxis	Protein kinase C delta type	Homo sapiens (human)
cellular response to hydrogen peroxide	Protein kinase C delta type	Homo sapiens (human)
cellular response to hydroperoxide	Protein kinase C delta type	Homo sapiens (human)
negative regulation of platelet aggregation	Protein kinase C delta type	Homo sapiens (human)
cellular senescence	Protein kinase C delta type	Homo sapiens (human)
positive regulation of phospholipid scramblase activity	Protein kinase C delta type	Homo sapiens (human)
cellular response to angiotensin	Protein kinase C delta type	Homo sapiens (human)
regulation of ceramide biosynthetic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of ceramide biosynthetic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of glucosylceramide catabolic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of sphingomyelin catabolic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Protein kinase C delta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C delta type	Homo sapiens (human)
neutrophil homeostasis	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of type III hypersensitivity	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of type I hypersensitivity	Tyrosine-protein kinase BTK	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase BTK	Homo sapiens (human)
B cell affinity maturation	Tyrosine-protein kinase BTK	Homo sapiens (human)
histamine secretion by mast cell	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of immunoglobulin production	Tyrosine-protein kinase BTK	Homo sapiens (human)
regulation of B cell cytokine production	Tyrosine-protein kinase BTK	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
regulation of B cell apoptotic process	Tyrosine-protein kinase BTK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase BTK	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase BTK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase BTK	Homo sapiens (human)
calcium-mediated signaling	Tyrosine-protein kinase BTK	Homo sapiens (human)
proteoglycan catabolic process	Tyrosine-protein kinase BTK	Homo sapiens (human)
negative regulation of B cell proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of B cell proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
response to lipopolysaccharide	Tyrosine-protein kinase BTK	Homo sapiens (human)
negative regulation of interleukin-10 production	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of interleukin-6 production	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Tyrosine-protein kinase BTK	Homo sapiens (human)
cellular response to reactive oxygen species	Tyrosine-protein kinase BTK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase BTK	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
B cell activation	Tyrosine-protein kinase BTK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of B cell differentiation	Tyrosine-protein kinase BTK	Homo sapiens (human)
cell maturation	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of phagocytosis	Tyrosine-protein kinase BTK	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
monocyte proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
cellular response to molecule of fungal origin	Tyrosine-protein kinase BTK	Homo sapiens (human)
apoptotic signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
cellular response to interleukin-7	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of interleukin-17A production	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of synoviocyte proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
eosinophil homeostasis	Tyrosine-protein kinase BTK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
neuron migration	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
natural killer cell differentiation	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
neuropeptide signaling pathway	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
spermatogenesis	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
forebrain cell migration	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
secretion by cell	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
negative regulation of toll-like receptor signaling pathway	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
ovulation cycle	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
apoptotic cell clearance	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
negative regulation of neuron apoptotic process	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
negative regulation of innate immune response	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
symbiont entry into host cell	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
negative regulation of inflammatory response	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
negative regulation of lymphocyte activation	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
neuron apoptotic process	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
establishment of localization in cell	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
vagina development	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
neuron cellular homeostasis	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
platelet aggregation	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
positive regulation of viral life cycle	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
nervous system development	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
phagocytosis	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
multicellular organism development	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
positive regulation of kinase activity	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
cell migration	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
positive regulation of myelination	Cyclin-dependent kinase 18	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 18	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 18	Homo sapiens (human)
endocytosis	Activated CDC42 kinase 1	Homo sapiens (human)
cell surface receptor signaling pathway	Activated CDC42 kinase 1	Homo sapiens (human)
small GTPase-mediated signal transduction	Activated CDC42 kinase 1	Homo sapiens (human)
phosphorylation	Activated CDC42 kinase 1	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Activated CDC42 kinase 1	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	Activated CDC42 kinase 1	Homo sapiens (human)
protein phosphorylation	Activated CDC42 kinase 1	Homo sapiens (human)
regulation of cell growth	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
regulation of cell-matrix adhesion	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
cell adhesion	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
embryo implantation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
lactation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
cell population proliferation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
negative regulation of cell population proliferation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
regulation of extracellular matrix disassembly	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
smooth muscle cell migration	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
collagen-activated tyrosine kinase receptor signaling pathway	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
ear development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
wound healing, spreading of cells	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
protein autophosphorylation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
mammary gland alveolus development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
smooth muscle cell-matrix adhesion	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
axon development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
neuron projection extension	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
multicellular organism development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of neuron projection development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of cytokine production	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
cellular defense response	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
activation of phospholipase C activity	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
T cell activation	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
gamma-delta T cell activation	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
NK T cell differentiation	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
regulation of sodium ion transport	Myotonin-protein kinase	Homo sapiens (human)
protein phosphorylation	Myotonin-protein kinase	Homo sapiens (human)
intracellular calcium ion homeostasis	Myotonin-protein kinase	Homo sapiens (human)
nuclear envelope organization	Myotonin-protein kinase	Homo sapiens (human)
regulation of heart contraction	Myotonin-protein kinase	Homo sapiens (human)
muscle cell apoptotic process	Myotonin-protein kinase	Homo sapiens (human)
regulation of myotube differentiation	Myotonin-protein kinase	Homo sapiens (human)
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	Myotonin-protein kinase	Homo sapiens (human)
regulation of synapse structural plasticity	Myotonin-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	Myotonin-protein kinase	Homo sapiens (human)
regulation of skeletal muscle contraction by calcium ion signaling	Myotonin-protein kinase	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of heart rate by hormone	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of membrane potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion homeostasis	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
cardiac muscle contraction	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of membrane repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
cellular response to xenobiotic stimulus	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane depolarization during action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization during action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization during cardiac muscle cell action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization during ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
negative regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
positive regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
negative regulation of potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion import across plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
vesicle targeting	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
immune response	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
innate immune response	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
post-translational protein modification	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
positive regulation of protein kinase activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
positive regulation of DNA-templated transcription	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
negative regulation of motor neuron apoptotic process	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
natural killer cell differentiation	Tyrosine-protein kinase Mer	Homo sapiens (human)
negative regulation of cytokine production	Tyrosine-protein kinase Mer	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Mer	Homo sapiens (human)
phagocytosis	Tyrosine-protein kinase Mer	Homo sapiens (human)
cell surface receptor signaling pathway	Tyrosine-protein kinase Mer	Homo sapiens (human)
cell-cell signaling	Tyrosine-protein kinase Mer	Homo sapiens (human)
spermatogenesis	Tyrosine-protein kinase Mer	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase Mer	Homo sapiens (human)
secretion by cell	Tyrosine-protein kinase Mer	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase Mer	Homo sapiens (human)
positive regulation of phagocytosis	Tyrosine-protein kinase Mer	Homo sapiens (human)
negative regulation of lymphocyte activation	Tyrosine-protein kinase Mer	Homo sapiens (human)
establishment of localization in cell	Tyrosine-protein kinase Mer	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase Mer	Homo sapiens (human)
retina development in camera-type eye	Tyrosine-protein kinase Mer	Homo sapiens (human)
vagina development	Tyrosine-protein kinase Mer	Homo sapiens (human)
neutrophil clearance	Tyrosine-protein kinase Mer	Homo sapiens (human)
negative regulation of leukocyte apoptotic process	Tyrosine-protein kinase Mer	Homo sapiens (human)
nervous system development	Tyrosine-protein kinase Mer	Homo sapiens (human)
positive regulation of kinase activity	Tyrosine-protein kinase Mer	Homo sapiens (human)
cell migration	Tyrosine-protein kinase Mer	Homo sapiens (human)
multicellular organism development	Tyrosine-protein kinase Mer	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Mer	Homo sapiens (human)
cell morphogenesis	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of protein phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of protein binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase 4	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Serine/threonine-protein kinase 4	Homo sapiens (human)
neural tube formation	Serine/threonine-protein kinase 4	Homo sapiens (human)
endocardium development	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein import into nucleus	Serine/threonine-protein kinase 4	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase 4	Homo sapiens (human)
central nervous system development	Serine/threonine-protein kinase 4	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 4	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
keratinocyte differentiation	Serine/threonine-protein kinase 4	Homo sapiens (human)
organ growth	Serine/threonine-protein kinase 4	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase 4	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of fat cell differentiation	Serine/threonine-protein kinase 4	Homo sapiens (human)
negative regulation of organ growth	Serine/threonine-protein kinase 4	Homo sapiens (human)
epithelial cell proliferation	Serine/threonine-protein kinase 4	Homo sapiens (human)
negative regulation of epithelial cell proliferation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein tetramerization	Serine/threonine-protein kinase 4	Homo sapiens (human)
canonical Wnt signaling pathway	Serine/threonine-protein kinase 4	Homo sapiens (human)
primitive hemopoiesis	Serine/threonine-protein kinase 4	Homo sapiens (human)
cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 4	Homo sapiens (human)
regulation of cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 4	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase 4	Homo sapiens (human)
hepatocyte apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of hepatocyte apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of substrate-dependent cell migration, cell attachment to substrate	Serine/threonine-protein kinase 4	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase 4	Homo sapiens (human)
lipid droplet disassembly	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to hypoxia	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
glucose metabolic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
chromatin remodeling	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cholesterol biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
autophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
signal transduction	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of cell population proliferation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
lipid biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to UV	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cold acclimation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to gamma radiation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of autophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of gene expression	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of gene expression	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
bile acid and bile salt transport	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
Wnt signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
fatty acid oxidation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to caffeine	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of TOR signaling	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of peptidyl-serine phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to oxidative stress	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
bile acid signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to glucose starvation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
glucose homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of circadian rhythm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of apoptotic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to estrogen	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of cholesterol biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of glycolytic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of glucosylceramide biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
rhythmic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of skeletal muscle tissue development	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of lipid catabolic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
fatty acid homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of vesicle-mediated transport	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
motor behavior	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
CAMKK-AMPK signaling cascade	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of stress granule assembly	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
neuron cellular homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to hydrogen peroxide	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to calcium ion	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to glucose stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to ethanol	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to prostaglandin E stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to organonitrogen compound	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to hypoxia	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to xenobiotic stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
energy homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of bile acid secretion	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of mitochondrial transcription	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of protein localization	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of hepatocyte apoptotic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of protein targeting to mitochondrion	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of adipose tissue development	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of TORC1 signaling	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of tubulin deacetylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein localization to lipid droplet	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of peptidyl-lysine acetylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of protein phosphorylation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
chromatin remodeling	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
exocytosis	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of cell population proliferation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of cell migration	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of microtubule polymerization	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of intracellular estrogen receptor signaling pathway	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
wound healing	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of JUN kinase activity	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
hepatocyte growth factor receptor signaling pathway	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
ephrin receptor signaling pathway	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
branching morphogenesis of an epithelial tube	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
neuron projection morphogenesis	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of stress fiber assembly	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
negative regulation of cell proliferation involved in contact inhibition	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
positive regulation of microtubule nucleation	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein localization to cytoplasmic stress granule	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of cell growth	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of interleukin-8 production	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of heterotypic cell-cell adhesion	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of smooth muscle cell apoptotic process	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of MAP kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of protein metabolic process	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of response to cytokine stimulus	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
ERK5 cascade	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
cellular response to growth factor stimulus	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
cellular response to laminar fluid shear stress	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of cell migration involved in sprouting angiogenesis	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of chemokine (C-X-C motif) ligand 2 production	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 7	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 7	Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathway	Mitogen-activated protein kinase 7	Homo sapiens (human)
cell differentiation	Mitogen-activated protein kinase 7	Homo sapiens (human)
calcineurin-NFAT signaling cascade	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of heterotypic cell-cell adhesion	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of smooth muscle cell apoptotic process	Mitogen-activated protein kinase 7	Homo sapiens (human)
regulation of angiogenesis	Mitogen-activated protein kinase 7	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of inflammatory response	Mitogen-activated protein kinase 7	Homo sapiens (human)
positive regulation of protein metabolic process	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of response to cytokine stimulus	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to hydrogen peroxide	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of calcineurin-NFAT signaling cascade	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to growth factor stimulus	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to laminar fluid shear stress	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Mitogen-activated protein kinase 7	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cardiac muscle hypertrophy	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of protein kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
adherens junction assembly	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
regulation of cytoskeleton organization	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of stress fiber assembly	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
dendritic spine development	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
bicellular tight junction assembly	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cellular response to organic cyclic compound	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein localization to cell-cell junction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
positive regulation of protein binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
neural tube formation	Serine/threonine-protein kinase 3	Homo sapiens (human)
endocardium development	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein import into nucleus	Serine/threonine-protein kinase 3	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 3	Homo sapiens (human)
JNK cascade	Serine/threonine-protein kinase 3	Homo sapiens (human)
central nervous system development	Serine/threonine-protein kinase 3	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 3	Homo sapiens (human)
organ growth	Serine/threonine-protein kinase 3	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase 3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase 3	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of fat cell differentiation	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase 3	Homo sapiens (human)
negative regulation of organ growth	Serine/threonine-protein kinase 3	Homo sapiens (human)
epithelial cell proliferation	Serine/threonine-protein kinase 3	Homo sapiens (human)
negative regulation of epithelial cell proliferation	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein tetramerization	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase 3	Homo sapiens (human)
canonical Wnt signaling pathway	Serine/threonine-protein kinase 3	Homo sapiens (human)
primitive hemopoiesis	Serine/threonine-protein kinase 3	Homo sapiens (human)
cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein localization to centrosome	Serine/threonine-protein kinase 3	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase 3	Homo sapiens (human)
hepatocyte apoptotic process	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein phosphorylation	cGMP-dependent protein kinase 2	Homo sapiens (human)
signal transduction	cGMP-dependent protein kinase 2	Homo sapiens (human)
positive regulation of chondrocyte differentiation	cGMP-dependent protein kinase 2	Homo sapiens (human)
tetrahydrobiopterin metabolic process	cGMP-dependent protein kinase 2	Homo sapiens (human)
protein localization to plasma membrane	cGMP-dependent protein kinase 2	Homo sapiens (human)
positive regulation of protein localization	cGMP-dependent protein kinase 2	Homo sapiens (human)
negative regulation of chloride transport	cGMP-dependent protein kinase 2	Homo sapiens (human)
protein kinase A signaling	cGMP-dependent protein kinase 2	Homo sapiens (human)
cell morphogenesis	Integrin-linked protein kinase	Homo sapiens (human)
integrin-mediated signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
branching involved in ureteric bud morphogenesis	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of protein phosphorylation	Integrin-linked protein kinase	Homo sapiens (human)
outflow tract morphogenesis	Integrin-linked protein kinase	Homo sapiens (human)
protein phosphorylation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of cell population proliferation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of signal transduction	Integrin-linked protein kinase	Homo sapiens (human)
fibroblast migration	Integrin-linked protein kinase	Homo sapiens (human)
nerve development	Integrin-linked protein kinase	Homo sapiens (human)
myelination in peripheral nervous system	Integrin-linked protein kinase	Homo sapiens (human)
cell projection organization	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of BMP signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of phosphorylation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Integrin-linked protein kinase	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Integrin-linked protein kinase	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of osteoblast differentiation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of DNA-templated transcription	Integrin-linked protein kinase	Homo sapiens (human)
neural precursor cell proliferation	Integrin-linked protein kinase	Homo sapiens (human)
platelet aggregation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Integrin-linked protein kinase	Homo sapiens (human)
negative regulation of neural precursor cell proliferation	Integrin-linked protein kinase	Homo sapiens (human)
cell-matrix adhesion	Integrin-linked protein kinase	Homo sapiens (human)
integrin-mediated signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
epithelial to mesenchymal transition	Rho-associated protein kinase 1	Homo sapiens (human)
aortic valve morphogenesis	Rho-associated protein kinase 1	Homo sapiens (human)
apical constriction	Rho-associated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
smooth muscle contraction	Rho-associated protein kinase 1	Homo sapiens (human)
leukocyte cell-cell adhesion	Rho-associated protein kinase 1	Homo sapiens (human)
signal transduction	Rho-associated protein kinase 1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Rho-associated protein kinase 1	Homo sapiens (human)
Rho protein signal transduction	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of autophagy	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of gene expression	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of phosphatase activity	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of angiogenesis	Rho-associated protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
membrane to membrane docking	Rho-associated protein kinase 1	Homo sapiens (human)
actin cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell adhesion	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell migration	Rho-associated protein kinase 1	Homo sapiens (human)
cortical actin cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
neuron projection development	Rho-associated protein kinase 1	Homo sapiens (human)
bleb assembly	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of protein binding	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of dephosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of myosin-light-chain-phosphatase activity	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of MAPK cascade	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of keratinocyte differentiation	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of neuron differentiation	Rho-associated protein kinase 1	Homo sapiens (human)
leukocyte migration	Rho-associated protein kinase 1	Homo sapiens (human)
leukocyte tethering or rolling	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of membrane protein ectodomain proteolysis	Rho-associated protein kinase 1	Homo sapiens (human)
myoblast migration	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of stress fiber assembly	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of focal adhesion assembly	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of focal adhesion assembly	Rho-associated protein kinase 1	Homo sapiens (human)
mRNA destabilization	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of biomineral tissue development	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
response to transforming growth factor beta	Rho-associated protein kinase 1	Homo sapiens (human)
protein localization to plasma membrane	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of synapse maturation	Rho-associated protein kinase 1	Homo sapiens (human)
podocyte cell migration	Rho-associated protein kinase 1	Homo sapiens (human)
motor neuron apoptotic process	Rho-associated protein kinase 1	Homo sapiens (human)
blood vessel diameter maintenance	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of angiotensin-activated signaling pathway	Rho-associated protein kinase 1	Homo sapiens (human)
neuron projection arborization	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of amyloid-beta clearance	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of synaptic vesicle endocytosis	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of amyloid-beta formation	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of amyloid precursor protein catabolic process	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of establishment of endothelial barrier	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of bicellular tight junction assembly	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of connective tissue replacement	Rho-associated protein kinase 1	Homo sapiens (human)
response to angiotensin	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of establishment of cell polarity	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell motility	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of motor neuron apoptotic process	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell junction assembly	Rho-associated protein kinase 1	Homo sapiens (human)
mitotic cytokinesis	Rho-associated protein kinase 1	Homo sapiens (human)
embryonic morphogenesis	Rho-associated protein kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
actomyosin structure organization	Rho-associated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
protein autophosphorylation	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
spliceosomal tri-snRNP complex assembly	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
spliceosomal snRNP assembly	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
mRNA splicing, via spliceosome	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
positive regulation of hippo signaling	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
mRNA cis splicing, via spliceosome	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
positive regulation of protein export from nucleus	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
regulation of mitotic cell cycle spindle assembly checkpoint	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
positive regulation of miRNA processing	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
MAPK cascade	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of protein phosphorylation	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
apoptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
inflammatory response	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
response to oxidative stress	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of gene expression	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein catabolic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of interleukin-8 production	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
response to tumor necrosis factor	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
intracellular signal transduction	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
peptidyl-serine autophosphorylation	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of apoptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of programmed cell death	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
negative regulation of canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of neuron apoptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of macrophage differentiation	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of JNK cascade	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein autophosphorylation	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of inflammatory response	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of necroptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
negative regulation of necroptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of programmed necrotic cell death	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of interleukin-6-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
T cell apoptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
necroptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
cellular response to hydrogen peroxide	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
regulation of ATP:ADP antiporter activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
cellular response to tumor necrosis factor	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
cellular response to growth factor stimulus	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
programmed necrotic cell death	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
ripoptosome assembly	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
necroptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of execution phase of apoptosis	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
ripoptosome assembly involved in necroptotic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of tumor necrosis factor-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
amyloid fibril formation	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
signal transduction	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
nervous system development	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
positive regulation of neuron projection development	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
regulation of skeletal muscle adaptation	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
cell differentiation	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
regulation of long-term neuronal synaptic plasticity	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
regulation of synapse structural plasticity	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
regulation of calcium ion transport	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
regulation of dendritic spine development	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
positive regulation of dendritic spine morphogenesis	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
positive regulation of synapse maturation	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
regulation of neuron migration	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
nervous system development	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of neuron projection development	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of skeletal muscle adaptation	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
insulin secretion	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
cell differentiation	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of calcium ion transport	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of cell growth	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of the force of heart contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of membrane depolarization	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of heart contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cell communication by electrical coupling	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
peptidyl-threonine phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
endoplasmic reticulum calcium ion homeostasis	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
relaxation of cardiac muscle	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of ryanodine-sensitive calcium-release channel activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cellular localization	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cellular response to calcium ion	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cardiac muscle cell contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cardiac muscle cell action potential	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cardiac muscle cell action potential involved in regulation of contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cell communication by electrical coupling involved in cardiac conduction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of relaxation of cardiac muscle	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
negative regulation of sodium ion transmembrane transport	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
negative regulation of sodium ion transmembrane transporter activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
chromatin remodeling	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nervous system development	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
circadian rhythm	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-threonine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of microtubule polymerization	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
positive regulation of RNA splicing	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
amyloid-beta formation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-serine autophosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of DNA damage response, signal transduction by p53 class mediator	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein autophosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of mRNA splicing, via spliceosome	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of DNA methylation-dependent heterochromatin formation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
positive regulation of protein deacetylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
skeletal system development	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
extraocular skeletal muscle development	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
calcium ion transport	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
muscle contraction	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
striated muscle contraction	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
endoplasmic reticulum organization	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
myoblast fusion	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
neuromuscular junction development	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
skeletal muscle adaptation	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
positive regulation of muscle contraction	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
skeletal muscle fiber development	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
release of sequestered calcium ion into cytosol	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
calcium ion transmembrane transport	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
cellular response to caffeine	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
calcium ion import across plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Activin receptor type-2B	Homo sapiens (human)
gastrulation with mouth forming second	Activin receptor type-2B	Homo sapiens (human)
kidney development	Activin receptor type-2B	Homo sapiens (human)
lymphangiogenesis	Activin receptor type-2B	Homo sapiens (human)
blood vessel remodeling	Activin receptor type-2B	Homo sapiens (human)
regulation of DNA-templated transcription	Activin receptor type-2B	Homo sapiens (human)
signal transduction	Activin receptor type-2B	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Activin receptor type-2B	Homo sapiens (human)
determination of left/right symmetry	Activin receptor type-2B	Homo sapiens (human)
mesoderm development	Activin receptor type-2B	Homo sapiens (human)
heart development	Activin receptor type-2B	Homo sapiens (human)
response to glucose	Activin receptor type-2B	Homo sapiens (human)
post-embryonic development	Activin receptor type-2B	Homo sapiens (human)
anterior/posterior pattern specification	Activin receptor type-2B	Homo sapiens (human)
insulin secretion	Activin receptor type-2B	Homo sapiens (human)
lung development	Activin receptor type-2B	Homo sapiens (human)
positive regulation of bone mineralization	Activin receptor type-2B	Homo sapiens (human)
BMP signaling pathway	Activin receptor type-2B	Homo sapiens (human)
pancreas development	Activin receptor type-2B	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-2B	Homo sapiens (human)
positive regulation of activin receptor signaling pathway	Activin receptor type-2B	Homo sapiens (human)
organ growth	Activin receptor type-2B	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Activin receptor type-2B	Homo sapiens (human)
positive regulation of osteoblast differentiation	Activin receptor type-2B	Homo sapiens (human)
embryonic foregut morphogenesis	Activin receptor type-2B	Homo sapiens (human)
skeletal system morphogenesis	Activin receptor type-2B	Homo sapiens (human)
roof of mouth development	Activin receptor type-2B	Homo sapiens (human)
lymphatic endothelial cell differentiation	Activin receptor type-2B	Homo sapiens (human)
artery development	Activin receptor type-2B	Homo sapiens (human)
venous blood vessel development	Activin receptor type-2B	Homo sapiens (human)
retina vasculature development in camera-type eye	Activin receptor type-2B	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Activin receptor type-2B	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-2B	Homo sapiens (human)
protein phosphorylation	Activin receptor type-2B	Homo sapiens (human)
outflow tract septum morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
atrioventricular valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cardiac muscle tissue development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
pharyngeal arch artery morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of gene expression	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
osteoblast differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
mesoderm formation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
maternal placenta development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endothelial cell proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lymphangiogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
blood vessel remodeling	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
chondrocyte development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of systemic arterial blood pressure	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
outflow tract morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
aortic valve development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
pulmonary valve development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
mitral valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
tricuspid valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endocardial cushion development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of cell proliferation involved in heart valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cellular response to starvation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
anterior/posterior pattern specification	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of epithelial cell migration	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
regulation of lung blood pressure	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
proteoglycan biosynthetic process	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of cell growth	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of bone mineralization	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
BMP signaling pathway	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
activin receptor signaling pathway	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
regulation of cell population proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of osteoblast differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of ossification	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of vasoconstriction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lung alveolus development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of smooth muscle cell proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of axon extension involved in axon guidance	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of muscle cell differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
limb development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endochondral bone morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
ventricular septum morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
atrial septum morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lung vasculature development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lymphatic endothelial cell differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
artery development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
venous blood vessel development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of cartilage development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
retina vasculature development in camera-type eye	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cellular response to BMP stimulus	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endothelial cell apoptotic process	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of chondrocyte proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
semi-lunar valve development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cellular response to growth factor stimulus	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
blood vessel development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein phosphorylation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein phosphorylation	Protein-tyrosine kinase 6	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of neuron projection development	Protein-tyrosine kinase 6	Homo sapiens (human)
cell migration	Protein-tyrosine kinase 6	Homo sapiens (human)
ERBB2 signaling pathway	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of DNA replication	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of epidermal growth factor receptor signaling pathway	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of cell cycle	Protein-tyrosine kinase 6	Homo sapiens (human)
negative regulation of growth	Protein-tyrosine kinase 6	Homo sapiens (human)
protein autophosphorylation	Protein-tyrosine kinase 6	Homo sapiens (human)
intestinal epithelial cell differentiation	Protein-tyrosine kinase 6	Homo sapiens (human)
negative regulation of protein tyrosine kinase activity	Protein-tyrosine kinase 6	Homo sapiens (human)
cellular response to retinoic acid	Protein-tyrosine kinase 6	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Protein-tyrosine kinase 6	Homo sapiens (human)
innate immune response	Protein-tyrosine kinase 6	Homo sapiens (human)
cell differentiation	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Protein-tyrosine kinase 6	Homo sapiens (human)
immune system development	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
heart development	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
embryonic forelimb morphogenesis	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
camera-type eye development	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
positive regulation of adenylate cyclase activity	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
positive regulation of muscle contraction	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
calcium ion transport into cytosol	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
cardiac conduction	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
calcium ion transmembrane transport via high voltage-gated calcium channel	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
calcium ion transmembrane transport	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
cardiac muscle cell action potential involved in contraction	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
membrane depolarization during cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
membrane depolarization during AV node cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
cell communication by electrical coupling involved in cardiac conduction	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
regulation of ventricular cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
membrane depolarization during atrial cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
calcium ion import across plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
protein phosphorylation	cGMP-dependent protein kinase 1	Homo sapiens (human)
neuron migration	cGMP-dependent protein kinase 1	Homo sapiens (human)
signal transduction	cGMP-dependent protein kinase 1	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	cGMP-dependent protein kinase 1	Homo sapiens (human)
spermatid development	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of inositol phosphate biosynthetic process	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of glutamate secretion	cGMP-dependent protein kinase 1	Homo sapiens (human)
dendrite development	cGMP-dependent protein kinase 1	Homo sapiens (human)
cGMP-mediated signaling	cGMP-dependent protein kinase 1	Homo sapiens (human)
cerebellum development	cGMP-dependent protein kinase 1	Homo sapiens (human)
actin cytoskeleton organization	cGMP-dependent protein kinase 1	Homo sapiens (human)
forebrain development	cGMP-dependent protein kinase 1	Homo sapiens (human)
positive regulation of circadian rhythm	cGMP-dependent protein kinase 1	Homo sapiens (human)
regulation of GTPase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
collateral sprouting	cGMP-dependent protein kinase 1	Homo sapiens (human)
relaxation of vascular associated smooth muscle	cGMP-dependent protein kinase 1	Homo sapiens (human)
cell growth involved in cardiac muscle cell development	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of platelet aggregation	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of vascular associated smooth muscle cell proliferation	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of vascular associated smooth muscle cell migration	cGMP-dependent protein kinase 1	Homo sapiens (human)
regulation of testosterone biosynthetic process	cGMP-dependent protein kinase 1	Homo sapiens (human)
protein kinase A signaling	cGMP-dependent protein kinase 1	Homo sapiens (human)
alternative mRNA splicing, via spliceosome	Cyclin-dependent kinase 13	Homo sapiens (human)
regulation of signal transduction	Cyclin-dependent kinase 13	Homo sapiens (human)
hemopoiesis	Cyclin-dependent kinase 13	Homo sapiens (human)
positive regulation of transcription elongation by RNA polymerase II	Cyclin-dependent kinase 13	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 13	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 13	Homo sapiens (human)
negative regulation of stem cell differentiation	Cyclin-dependent kinase 13	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 13	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
nucleocytoplasmic transport	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
signal transduction	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
nervous system development	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of neuron projection development	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
cell differentiation	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
negative regulation of protein binding	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
regulation of protein localization	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
intracellular signal transduction	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
regulation of protein binding	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of protein export from nucleus	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
regulation of muscle cell differentiation	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of muscle cell differentiation	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of synapse structural plasticity	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of syncytium formation by plasma membrane fusion	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of dendritic spine development	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
immune response	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
gene expression	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of lipid storage	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of type I interferon production	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
response to interferon-beta	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
regulation of protein-containing complex assembly	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
mRNA stabilization	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
defense response to virus	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
type I interferon-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of type I interferon-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
interleukin-17-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
cellular response to virus	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
peptidyl-serine phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
MAPK cascade	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
oocyte maturation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to hypoxia	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
sprouting angiogenesis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
adaptive immune response	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
marginal zone B cell differentiation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to ischemia	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein phosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cellular defense response	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
signal transduction	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cell surface receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
signal complex assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
integrin-mediated signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell population proliferation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of cell population proliferation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of cell shape	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to xenobiotic stimulus	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to mechanical stimulus	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to hormone	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to glucose	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of endothelial cell migration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of muscle cell apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of macrophage chemotaxis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of neuron projection development	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
glial cell proliferation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of cell adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell growth	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell migration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of bone mineralization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of actin filament polymerization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cortical cytoskeleton organization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
neuron projection development	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of actin cytoskeleton organization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
ionotropic glutamate receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to immobilization stress	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to cocaine	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to hydrogen peroxide	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
activation of Janus kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
stress fiber assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to cation stress	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of potassium ion transport	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of neuron apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
blood vessel endothelial cell migration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
bone resorption	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to ethanol	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of myeloid cell differentiation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of translation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of angiogenesis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of protein kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of JNK cascade	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein autophosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
focal adhesion assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of synaptic plasticity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to cAMP	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to calcium ion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
long-term synaptic potentiation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
long-term synaptic depression	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein-containing complex assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
chemokine-mediated signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cellular response to retinoic acid	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cellular response to fluid shear stress	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
endothelin receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of postsynaptic density assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
postsynaptic modulation of chemical synaptic transmission	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of ubiquitin-dependent protein catabolic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of ubiquitin-dependent protein catabolic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of excitatory postsynaptic potential	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of B cell chemotaxis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of heart rate	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cardiac conduction system development	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cardiac ventricle development	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
brainstem development	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
sodium ion transport	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
positive regulation of sodium ion transport	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
response to denervation involved in regulation of muscle adaptation	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
telencephalon development	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cerebellum development	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
sodium ion transmembrane transport	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
positive regulation of action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cardiac muscle contraction	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane repolarization	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of atrial cardiac muscle cell membrane depolarization	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of atrial cardiac muscle cell membrane repolarization	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane depolarization	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cellular response to calcium ion	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cardiac muscle cell action potential involved in contraction	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of cardiac muscle cell contraction	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
ventricular cardiac muscle cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during cardiac muscle cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
atrial cardiac muscle cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
SA node cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
AV node cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
bundle of His cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during AV node cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during SA node cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during Purkinje myocyte cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during bundle of His cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
AV node cell to bundle of His cell communication	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane depolarization during atrial cardiac muscle cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
regulation of sodium ion transmembrane transport	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
apoptotic process	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
cell population proliferation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
hemopoiesis	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
positive regulation of apoptotic process	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein autophosphorylation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
neural precursor cell proliferation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein phosphorylation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
mitotic sister chromatid segregation	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
DNA repair	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
response to radiation	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
establishment of mitotic sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
establishment of meiotic sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
somatic stem cell population maintenance	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
cell division	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
meiotic cell cycle	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
response to DNA damage checkpoint signaling	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic spindle assembly	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
double-strand break repair via homologous recombination	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
chromatin remodeling	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
negative regulation of gene expression	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
regulation of cell fate specification	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
negative regulation of DNA-templated transcription	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
positive regulation of DNA-templated transcription	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
regulation of synapse assembly	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
terminal button organization	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
regulation of stem cell differentiation	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
angiogenesis	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Serine/threonine-protein kinase D1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase D1	Homo sapiens (human)
inflammatory response	Serine/threonine-protein kinase D1	Homo sapiens (human)
Golgi organization	Serine/threonine-protein kinase D1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
integrin-mediated signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
nervous system development	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of endothelial cell migration	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of gene expression	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of keratinocyte proliferation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of neuron projection development	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril	Serine/threonine-protein kinase D1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D1	Homo sapiens (human)
cell differentiation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to amino acid starvation	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase D1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of protein import into nucleus	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Serine/threonine-protein kinase D1	Homo sapiens (human)
innate immune response	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of osteoblast differentiation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of cell size	Serine/threonine-protein kinase D1	Homo sapiens (human)
negative regulation of endocytosis	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of protein export from nucleus	Serine/threonine-protein kinase D1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
Golgi vesicle transport	Serine/threonine-protein kinase D1	Homo sapiens (human)
defense response to Gram-negative bacterium	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of sarcomere organization	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to hydroperoxide	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to norepinephrine stimulus	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of peptide hormone secretion	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to angiotensin	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to phorbol 13-acetate 12-myristate	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to endothelin	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of integrin-mediated signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
DNA damage checkpoint signaling	Serine/threonine-protein kinase 38	Homo sapiens (human)
chromatin organization	Serine/threonine-protein kinase 38	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 38	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase 38	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 38	Homo sapiens (human)
protein modification process	Serine/threonine-protein kinase 38	Homo sapiens (human)
negative regulation of MAP kinase activity	Serine/threonine-protein kinase 38	Homo sapiens (human)
postsynapse organization	Serine/threonine-protein kinase 38	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 38	Homo sapiens (human)
neural crest cell migration	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of protein phosphorylation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
signal transduction	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
nervous system development	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
synapse assembly	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
heart development	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
lactation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of cell population proliferation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
negative regulation of cell population proliferation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
embryonic pattern specification	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cell migration	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
central nervous system morphogenesis	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
olfactory bulb interneuron differentiation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
regulation of cell migration	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
ERBB4 signaling pathway	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
ERBB2-ERBB4 signaling pathway	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
ERBB4-ERBB4 signaling pathway	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
mitochondrial fragmentation involved in apoptotic process	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cell fate commitment	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of DNA-templated transcription	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
protein autophosphorylation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
mammary gland epithelial cell differentiation	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
mammary gland alveolus development	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cardiac muscle tissue regeneration	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
establishment of planar polarity involved in nephron morphogenesis	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
neurotransmitter receptor localization to postsynaptic specialization membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of protein localization to cell surface	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
negative regulation of apoptotic process	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
positive regulation of kinase activity	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
multicellular organism development	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
neurogenesis	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
chemical synaptic transmission	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
negative regulation of cell population proliferation	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
positive regulation of apoptotic process	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
negative regulation of cell cycle	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
positive regulation of protein phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
brain development	Ephrin type-A receptor 7	Homo sapiens (human)
phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of cell-cell adhesion	Ephrin type-A receptor 7	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of protein autophosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ephrin type-A receptor 7	Homo sapiens (human)
positive regulation of neuron apoptotic process	Ephrin type-A receptor 7	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 7	Homo sapiens (human)
negative regulation of collateral sprouting	Ephrin type-A receptor 7	Homo sapiens (human)
branching morphogenesis of a nerve	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
modulation of chemical synaptic transmission	Ephrin type-A receptor 7	Homo sapiens (human)
negative chemotaxis	Ephrin type-A receptor 7	Homo sapiens (human)
neuron apoptotic process	Ephrin type-A receptor 7	Homo sapiens (human)
negative regulation of synapse assembly	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Ephrin type-A receptor 7	Homo sapiens (human)
nephric duct morphogenesis	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of postsynapse organization	Ephrin type-A receptor 7	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 7	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
cholesterol biosynthetic process	Delta(24)-sterol reductase	Homo sapiens (human)
cholesterol biosynthetic process	Delta(24)-sterol reductase	Homo sapiens (human)
Ras protein signal transduction	Delta(24)-sterol reductase	Homo sapiens (human)
protein localization	Delta(24)-sterol reductase	Homo sapiens (human)
negative regulation of cell population proliferation	Delta(24)-sterol reductase	Homo sapiens (human)
response to hormone	Delta(24)-sterol reductase	Homo sapiens (human)
tissue development	Delta(24)-sterol reductase	Homo sapiens (human)
male genitalia development	Delta(24)-sterol reductase	Homo sapiens (human)
plasminogen activation	Delta(24)-sterol reductase	Homo sapiens (human)
cholesterol biosynthetic process via desmosterol	Delta(24)-sterol reductase	Homo sapiens (human)
cholesterol biosynthetic process via lathosterol	Delta(24)-sterol reductase	Homo sapiens (human)
amyloid precursor protein catabolic process	Delta(24)-sterol reductase	Homo sapiens (human)
skin development	Delta(24)-sterol reductase	Homo sapiens (human)
membrane organization	Delta(24)-sterol reductase	Homo sapiens (human)
steroid metabolic process	Delta(24)-sterol reductase	Homo sapiens (human)
protein phosphorylation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
chemical synaptic transmission	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of cell growth	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
negative regulation of TOR signaling	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
negative regulation of apoptotic process	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
regulation of translation in response to stress	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of cell differentiation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
hepatocyte proliferation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of hepatic stellate cell activation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of protein phosphorylation	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
spermatogenesis	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
negative regulation of protein autophosphorylation	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
regulation of protein localization	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
negative regulation of phosphorylation	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
positive regulation of stress fiber assembly	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
establishment of vesicle localization	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
negative regulation of protein serine/threonine kinase activity	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
podocyte cell migration	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
negative regulation of cilium assembly	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
actin cytoskeleton organization	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein phosphorylation	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
smooth muscle contraction	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
tonic smooth muscle contraction	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of cell migration	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
bleb assembly	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of calcium ion transport	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
aorta smooth muscle tissue morphogenesis	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cellular hypotonic response	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of wound healing	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Mitogen-activated protein kinase 11	Homo sapiens (human)
osteoblast differentiation	Mitogen-activated protein kinase 11	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 11	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Mitogen-activated protein kinase 11	Homo sapiens (human)
positive regulation of interleukin-12 production	Mitogen-activated protein kinase 11	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase 11	Homo sapiens (human)
positive regulation of muscle cell differentiation	Mitogen-activated protein kinase 11	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 11	Homo sapiens (human)
cardiac muscle cell proliferation	Mitogen-activated protein kinase 11	Homo sapiens (human)
negative regulation of cardiac muscle cell proliferation	Mitogen-activated protein kinase 11	Homo sapiens (human)
bone development	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular response to interleukin-1	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular response to UV-B	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular response to virus	Mitogen-activated protein kinase 11	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 11	Homo sapiens (human)
G1 to G0 transition	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase STK11	Homo sapiens (human)
tissue homeostasis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
vasculature development	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein dephosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase STK11	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase STK11	Homo sapiens (human)
spermatogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of cell population proliferation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to ionizing radiation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of cell growth	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
activation of protein kinase activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to glucagon	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to lipid	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein localization to nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
glucose homeostasis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
anoikis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive thymic T cell selection	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of gluconeogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of dendrite morphogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of axonogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
T cell receptor signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
Golgi localization	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of cell cycle	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase STK11	Homo sapiens (human)
epithelial cell proliferation involved in prostate gland development	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of epithelial cell proliferation involved in prostate gland development	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cellular response to UV-B	Serine/threonine-protein kinase STK11	Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediator	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to thyroid hormone	Serine/threonine-protein kinase STK11	Homo sapiens (human)
dendrite extension	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of protein localization to nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of vesicle transport along microtubule	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of TORC1 signaling	Serine/threonine-protein kinase STK11	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of Wnt signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
visual perception	Rhodopsin kinase GRK1	Homo sapiens (human)
regulation of G protein-coupled receptor signaling pathway	Rhodopsin kinase GRK1	Homo sapiens (human)
rhodopsin mediated signaling pathway	Rhodopsin kinase GRK1	Homo sapiens (human)
regulation of opsin-mediated signaling pathway	Rhodopsin kinase GRK1	Homo sapiens (human)
protein autophosphorylation	Rhodopsin kinase GRK1	Homo sapiens (human)
protein phosphorylation	Rhodopsin kinase GRK1	Homo sapiens (human)
regulation of signal transduction	Rhodopsin kinase GRK1	Homo sapiens (human)
activation of protein kinase B activity	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of MAP kinase activity	NT-3 growth factor receptor	Homo sapiens (human)
negative regulation of protein phosphorylation	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	NT-3 growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	NT-3 growth factor receptor	Homo sapiens (human)
nervous system development	NT-3 growth factor receptor	Homo sapiens (human)
heart development	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of cell population proliferation	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of gene expression	NT-3 growth factor receptor	Homo sapiens (human)
cell differentiation	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of cell migration	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	NT-3 growth factor receptor	Homo sapiens (human)
neurotrophin signaling pathway	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of positive chemotaxis	NT-3 growth factor receptor	Homo sapiens (human)
activation of GTPase activity	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of neuron projection development	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	NT-3 growth factor receptor	Homo sapiens (human)
cellular response to nerve growth factor stimulus	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	NT-3 growth factor receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	NT-3 growth factor receptor	Homo sapiens (human)
multicellular organism development	NT-3 growth factor receptor	Homo sapiens (human)
B cell homeostasis	Serine/threonine-protein kinase N1	Homo sapiens (human)
B cell apoptotic process	Serine/threonine-protein kinase N1	Homo sapiens (human)
negative regulation of protein phosphorylation	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of germinal center formation	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of immunoglobulin production	Serine/threonine-protein kinase N1	Homo sapiens (human)
renal system process	Serine/threonine-protein kinase N1	Homo sapiens (human)
chromatin remodeling	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase N1	Homo sapiens (human)
hyperosmotic response	Serine/threonine-protein kinase N1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase N1	Homo sapiens (human)
epithelial cell migration	Serine/threonine-protein kinase N1	Homo sapiens (human)
negative regulation of B cell proliferation	Serine/threonine-protein kinase N1	Homo sapiens (human)
post-translational protein modification	Serine/threonine-protein kinase N1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase N1	Homo sapiens (human)
spleen development	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of androgen receptor signaling pathway	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of cell motility	Serine/threonine-protein kinase N1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase N1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase N2	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase N2	Homo sapiens (human)
cell adhesion	Serine/threonine-protein kinase N2	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase N2	Homo sapiens (human)
epithelial cell migration	Serine/threonine-protein kinase N2	Homo sapiens (human)
cell projection organization	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of cytokinesis	Serine/threonine-protein kinase N2	Homo sapiens (human)
apical junction assembly	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of viral genome replication	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of mitotic cell cycle	Serine/threonine-protein kinase N2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase N2	Homo sapiens (human)
regulation of cell motility	Serine/threonine-protein kinase N2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase N2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to lipopolysaccharide	Mitogen-activated protein kinase 14	Homo sapiens (human)
DNA damage checkpoint signaling	Mitogen-activated protein kinase 14	Homo sapiens (human)
cell morphogenesis	Mitogen-activated protein kinase 14	Homo sapiens (human)
cartilage condensation	Mitogen-activated protein kinase 14	Homo sapiens (human)
angiogenesis	Mitogen-activated protein kinase 14	Homo sapiens (human)
osteoblast differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
placenta development	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to dietary excess	Mitogen-activated protein kinase 14	Homo sapiens (human)
chondrocyte differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Mitogen-activated protein kinase 14	Homo sapiens (human)
glucose metabolic process	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 14	Homo sapiens (human)
transcription by RNA polymerase II	Mitogen-activated protein kinase 14	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase 14	Homo sapiens (human)
chemotaxis	Mitogen-activated protein kinase 14	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 14	Homo sapiens (human)
cell surface receptor signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
skeletal muscle tissue development	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myotube differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 14	Homo sapiens (human)
fatty acid oxidation	Mitogen-activated protein kinase 14	Homo sapiens (human)
platelet activation	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of ossification	Mitogen-activated protein kinase 14	Homo sapiens (human)
osteoclast differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of cyclase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to muramyl dipeptide	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of interleukin-12 production	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to insulin	Mitogen-activated protein kinase 14	Homo sapiens (human)
negative regulation of hippo signaling	Mitogen-activated protein kinase 14	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to muscle stretch	Mitogen-activated protein kinase 14	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of protein import into nucleus	Mitogen-activated protein kinase 14	Homo sapiens (human)
signal transduction in response to DNA damage	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myoblast differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 14	Homo sapiens (human)
glucose import	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of glucose import	Mitogen-activated protein kinase 14	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
stem cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
striated muscle cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of muscle cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Mitogen-activated protein kinase 14	Homo sapiens (human)
bone development	Mitogen-activated protein kinase 14	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to lipoteichoic acid	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to ionizing radiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to UV-B	Mitogen-activated protein kinase 14	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of brown fat cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 14	Homo sapiens (human)
stress-induced premature senescence	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to virus	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of synaptic membrane adhesion	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of cytokine production involved in inflammatory response	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myoblast fusion	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myeloid dendritic cell cytokine production	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
adaptive immune response	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
inflammatory response	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
signal transduction	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
long-term memory	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
regulation of T cell differentiation in thymus	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
myeloid dendritic cell differentiation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
regulation of osteoclast differentiation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
positive regulation of DNA-templated transcription	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
intracellular signal transduction	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
microtubule-based process	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of neuron apoptotic process	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
cell cycle G1/S phase transition	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
negative regulation of amyloid-beta formation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
vasculogenesis	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
neuron migration	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
learning	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
circadian rhythm	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
feeding behavior	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of cell population proliferation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of gene expression	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of neuron projection development	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
glutamate secretion	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
neuronal action potential propagation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
central nervous system neuron development	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
cerebral cortex development	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
myelination in peripheral nervous system	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
neuron differentiation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
brain-derived neurotrophic factor receptor signaling pathway	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
neurotrophin signaling pathway	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
mechanoreceptor differentiation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
regulation of GTPase activity	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of MAPK cascade	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
negative regulation of neuron apoptotic process	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
retinal rod cell development	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
protein autophosphorylation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
oligodendrocyte differentiation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
peripheral nervous system neuron development	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of axonogenesis	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of synapse assembly	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
long-term synaptic potentiation	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
cellular response to amino acid stimulus	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
trans-synaptic signaling by BDNF, modulating synaptic transmission	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
negative regulation of anoikis	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of kinase activity	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
multicellular organism development	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
cellular response to brain-derived neurotrophic factor stimulus	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
trans-synaptic signaling by neuropeptide, modulating synaptic transmission	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 6	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 6	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 6	Homo sapiens (human)
positive regulation of dendritic spine development	Mitogen-activated protein kinase 6	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 6	Homo sapiens (human)
response to hypoxia	Carbonic anhydrase 9	Homo sapiens (human)
morphogenesis of an epithelium	Carbonic anhydrase 9	Homo sapiens (human)
response to xenobiotic stimulus	Carbonic anhydrase 9	Homo sapiens (human)
response to testosterone	Carbonic anhydrase 9	Homo sapiens (human)
secretion	Carbonic anhydrase 9	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 9	Homo sapiens (human)
carbohydrate metabolic process	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
glycogen biosynthetic process	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
ossification	Discoidin domain-containing receptor 2	Homo sapiens (human)
endochondral bone growth	Discoidin domain-containing receptor 2	Homo sapiens (human)
cell adhesion	Discoidin domain-containing receptor 2	Homo sapiens (human)
signal transduction	Discoidin domain-containing receptor 2	Homo sapiens (human)
regulation of extracellular matrix disassembly	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of fibroblast migration	Discoidin domain-containing receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Discoidin domain-containing receptor 2	Homo sapiens (human)
collagen fibril organization	Discoidin domain-containing receptor 2	Homo sapiens (human)
regulation of bone mineralization	Discoidin domain-containing receptor 2	Homo sapiens (human)
biomineral tissue development	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of collagen biosynthetic process	Discoidin domain-containing receptor 2	Homo sapiens (human)
regulation of tissue remodeling	Discoidin domain-containing receptor 2	Homo sapiens (human)
chondrocyte proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
response to muscle stretch	Discoidin domain-containing receptor 2	Homo sapiens (human)
collagen-activated tyrosine kinase receptor signaling pathway	Discoidin domain-containing receptor 2	Homo sapiens (human)
negative regulation of apoptotic process	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of osteoblast differentiation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of protein kinase activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein autophosphorylation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of fibroblast proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
cellular response to hypoxia	Discoidin domain-containing receptor 2	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of extracellular matrix disassembly	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of wound healing	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	Discoidin domain-containing receptor 2	Homo sapiens (human)
negative regulation of hydrogen peroxide-mediated programmed cell death	Discoidin domain-containing receptor 2	Homo sapiens (human)
cellular response to angiotensin	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell migration	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of hepatic stellate cell proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of hepatic stellate cell activation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of neuron projection development	Discoidin domain-containing receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Discoidin domain-containing receptor 2	Homo sapiens (human)
multicellular organism development	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein phosphorylation	AP2-associated protein kinase 1	Homo sapiens (human)
regulation of protein localization	AP2-associated protein kinase 1	Homo sapiens (human)
positive regulation of Notch signaling pathway	AP2-associated protein kinase 1	Homo sapiens (human)
protein stabilization	AP2-associated protein kinase 1	Homo sapiens (human)
membrane organization	AP2-associated protein kinase 1	Homo sapiens (human)
presynaptic endocytosis	AP2-associated protein kinase 1	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	AP2-associated protein kinase 1	Homo sapiens (human)
regulation of vascular permeability involved in acute inflammatory response	Myosin light chain kinase 3	Homo sapiens (human)
protein phosphorylation	Myosin light chain kinase 3	Homo sapiens (human)
sarcomere organization	Myosin light chain kinase 3	Homo sapiens (human)
sarcomerogenesis	Myosin light chain kinase 3	Homo sapiens (human)
cardiac myofibril assembly	Myosin light chain kinase 3	Homo sapiens (human)
positive regulation of sarcomere organization	Myosin light chain kinase 3	Homo sapiens (human)
cellular response to interleukin-1	Myosin light chain kinase 3	Homo sapiens (human)
biological_process	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
cellular response to heat	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein stabilization	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein folding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
regulation of heart rate	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
regulation of cardiac muscle contraction	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
bundle of His cell to Purkinje myocyte communication	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
regulation of cardiac conduction	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
natural killer cell differentiation	Rab-like protein 3	Homo sapiens (human)
B cell differentiation	Rab-like protein 3	Homo sapiens (human)
T cell differentiation in thymus	Rab-like protein 3	Homo sapiens (human)
regulation of Ras protein signal transduction	Rab-like protein 3	Homo sapiens (human)
protein stabilization	Rab-like protein 3	Homo sapiens (human)
regulation of protein lipidation	Rab-like protein 3	Homo sapiens (human)
intracellular protein transport	Rab-like protein 3	Homo sapiens (human)
negative regulation of GTPase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
MAPK cascade	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of protein phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein import into nucleus	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
endocytosis	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
autophagy	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
response to oxidative stress	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrion organization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
endoplasmic reticulum organization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
Golgi organization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
lysosome organization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
JNK cascade	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
Rho protein signal transduction	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
spermatogenesis	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
neuromuscular junction development	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein localization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
determination of adult lifespan	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to starvation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of autophagy	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of autophagy	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of protein kinase A signaling	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of protein processing	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of neuron projection development	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of neuron maturation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of macroautophagy	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
calcium-mediated signaling	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
striatum development	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
olfactory bulb development	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
tangential migration from the subventricular zone to the olfactory bulb	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein ubiquitination	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of protein stability	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of protein binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to oxidative stress	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to reactive oxygen species	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
intracellular signal transduction	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of kidney size	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
exploration behavior	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
locomotory exploration behavior	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of lysosomal lumen pH	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of locomotion	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of membrane potential	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of programmed cell death	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of MAP kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
GTP metabolic process	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein autophosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
intracellular distribution of mitochondria	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
neuron projection morphogenesis	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrion localization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of mitochondrial depolarization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of synaptic transmission, glutamatergic	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
canonical Wnt signaling pathway	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
excitatory postsynaptic potential	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of dopamine receptor signaling pathway	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of dopamine receptor signaling pathway	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of ER to Golgi vesicle-mediated transport	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of canonical Wnt signaling pathway	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of dendritic spine morphogenesis	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein localization to mitochondrion	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein localization to endoplasmic reticulum exit site	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to manganese ion	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of mitochondrial fission	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of excitatory postsynaptic potential	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
neuron projection arborization	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of synaptic vesicle endocytosis	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein autoubiquitination	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of neuroblast proliferation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of synaptic vesicle transport	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of late endosome to lysosome transport	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of autophagosome assembly	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of protein targeting to mitochondrion	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
negative regulation of protein processing involved in protein targeting to mitochondrion	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to dopamine	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of microglial cell activation	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
Wnt signalosome assembly	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of retrograde transport, endosome to Golgi	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of CAMKK-AMPK signaling cascade	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of branching morphogenesis of a nerve	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of synaptic vesicle exocytosis	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
regulation of reactive oxygen species metabolic process	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
signal transduction	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actomyosin structure organization	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
actomyosin structure organization	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
fatty acid beta-oxidation	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase N3	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase N3	Homo sapiens (human)
epithelial cell migration	Serine/threonine-protein kinase N3	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase N3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase N3	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
smoothened signaling pathway	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
negative regulation of smoothened signaling pathway	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
positive regulation of smoothened signaling pathway	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
fibroblast activation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cellular senescence	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
reticulophagy	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
piecemeal microautophagy of the nucleus	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
response to starvation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
autophagosome assembly	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
regulation of autophagy	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
positive regulation of kinase activity	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
negative regulation of apoptotic process	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
cellular response to fibroblast growth factor stimulus	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
positive regulation of fibroblast growth factor receptor signaling pathway	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)
cellular response to stress	Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)
fatty acid beta-oxidation	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mRNA processing	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
rRNA catabolic process	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
apoptotic chromosome condensation	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
negative regulation of DNA-templated transcription	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
IRE1-mediated unfolded protein response	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
neuron migration	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
positive regulation of neuron projection development	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
Wnt signaling pathway	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
activation of protein kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of cytoskeleton organization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
mitochondrion localization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
axon development	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
establishment or maintenance of cell polarity regulating cell shape	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of microtubule binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
central nervous system development	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
DNA duplex unwinding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
mitochondrial large ribosomal subunit assembly	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
DNA repair	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
negative regulation of microtubule depolymerization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
central nervous system neuron development	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
regulation of cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
neuron cellular homeostasis	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
execution phase of apoptosis	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
positive regulation of protein acetylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein phosphorylation	STE20-related kinase adapter protein alpha	Homo sapiens (human)
G1 to G0 transition	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein export from nucleus	STE20-related kinase adapter protein alpha	Homo sapiens (human)
activation of protein kinase activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
skeletal muscle contraction	Myosin-14	Homo sapiens (human)
mitochondrion organization	Myosin-14	Homo sapiens (human)
skeletal muscle tissue development	Myosin-14	Homo sapiens (human)
sensory perception of sound	Myosin-14	Homo sapiens (human)
regulation of cell shape	Myosin-14	Homo sapiens (human)
neuronal action potential	Myosin-14	Homo sapiens (human)
actin filament-based movement	Myosin-14	Homo sapiens (human)
actomyosin structure organization	Myosin-14	Homo sapiens (human)
vocalization behavior	Myosin-14	Homo sapiens (human)
negative regulation of mitochondrial fusion	AarF domain-containing protein kinase 1	Homo sapiens (human)
positive regulation of cristae formation	AarF domain-containing protein kinase 1	Homo sapiens (human)
mitochondrion organization	AarF domain-containing protein kinase 1	Homo sapiens (human)
lipid homeostasis	AarF domain-containing protein kinase 1	Homo sapiens (human)
chromatin organization	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
chromosome segregation	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
negative regulation of autophagy	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
nucleus localization	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
cellular response to gamma radiation	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
regulation of chromatin organization	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 32C	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 32C	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
negative regulation of insulin secretion involved in cellular response to glucose stimulus	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
regulation of interleukin-1-mediated signaling pathway	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
eye development	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
protein phosphorylation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
cell population proliferation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
positive regulation of cell population proliferation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
anterior/posterior pattern specification	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
retina layer formation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
neuron differentiation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
adherens junction assembly	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
positive regulation of angiogenesis	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
embryonic camera-type eye morphogenesis	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
embryonic retina morphogenesis in camera-type eye	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
definitive hemopoiesis	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
lens induction in camera-type eye	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
iris morphogenesis	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
endothelial cell apoptotic process	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
smoothened signaling pathway	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
inflammatory response	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
nervous system development	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
positive regulation of neuron projection development	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
positive regulation of apoptotic process	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
negative regulation of apoptotic process	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
positive regulation of phagocytosis	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
regulation of dendrite development	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
positive regulation of respiratory burst	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
regulation of granulocyte chemotaxis	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
positive regulation of neutrophil chemotaxis	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
response to UV	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
response to tumor necrosis factor	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein modification process	Cyclin-dependent kinase-like 3	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase-like 3	Homo sapiens (human)
negative regulation of axon extension	Cyclin-dependent kinase-like 3	Homo sapiens (human)
positive regulation of dendrite morphogenesis	Cyclin-dependent kinase-like 3	Homo sapiens (human)
dendrite extension	Cyclin-dependent kinase-like 3	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase-like 3	Homo sapiens (human)
MAPK cascade	MAP kinase-activated protein kinase 5	Homo sapiens (human)
regulation of translation	MAP kinase-activated protein kinase 5	Homo sapiens (human)
signal transduction	MAP kinase-activated protein kinase 5	Homo sapiens (human)
Ras protein signal transduction	MAP kinase-activated protein kinase 5	Homo sapiens (human)
negative regulation of TOR signaling	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein autophosphorylation	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of telomerase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of dendritic spine development	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cellular senescence	MAP kinase-activated protein kinase 5	Homo sapiens (human)
stress-induced premature senescence	MAP kinase-activated protein kinase 5	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of telomere capping	MAP kinase-activated protein kinase 5	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP kinase-activated protein kinase 5	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
exocytosis	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
regulation of neuron projection development	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
neuron differentiation	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
ERAD pathway	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
regulation of ATP-dependent activity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
microtubule cytoskeleton organization involved in establishment of planar polarity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
regulation of retrograde protein transport, ER to cytosol	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
regulation of synaptic vesicle clustering	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase NIM1	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
response to starvation	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
collateral sprouting	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
axon extension	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
reticulophagy	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
piecemeal microautophagy of the nucleus	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
negative regulation of collateral sprouting	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
autophagosome assembly	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
microvillus assembly	Misshapen-like kinase 1	Homo sapiens (human)
regulation of cell-matrix adhesion	Misshapen-like kinase 1	Homo sapiens (human)
protein phosphorylation	Misshapen-like kinase 1	Homo sapiens (human)
JNK cascade	Misshapen-like kinase 1	Homo sapiens (human)
chemical synaptic transmission	Misshapen-like kinase 1	Homo sapiens (human)
brain development	Misshapen-like kinase 1	Homo sapiens (human)
regulation of cell-cell adhesion	Misshapen-like kinase 1	Homo sapiens (human)
actin cytoskeleton organization	Misshapen-like kinase 1	Homo sapiens (human)
regulation of cell migration	Misshapen-like kinase 1	Homo sapiens (human)
positive regulation of JNK cascade	Misshapen-like kinase 1	Homo sapiens (human)
protein autophosphorylation	Misshapen-like kinase 1	Homo sapiens (human)
dendrite morphogenesis	Misshapen-like kinase 1	Homo sapiens (human)
positive regulation of p38MAPK cascade	Misshapen-like kinase 1	Homo sapiens (human)
regulation of AMPA receptor activity	Misshapen-like kinase 1	Homo sapiens (human)
MAPK cascade	Misshapen-like kinase 1	Homo sapiens (human)
neuron projection morphogenesis	Misshapen-like kinase 1	Homo sapiens (human)
regulation of MAPK cascade	Misshapen-like kinase 1	Homo sapiens (human)
hippocampus development	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
pyramidal neuron development	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
protein localization to nucleus	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
negative regulation of protein localization to nucleus	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
intracellular signal transduction	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform alpha-like	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform alpha-like	Homo sapiens (human)
signal transduction	Casein kinase I isoform alpha-like	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Casein kinase I isoform alpha-like	Homo sapiens (human)
kidney development	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
liver development	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of receptor recycling	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of receptor internalization	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
positive regulation of receptor internalization	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
triglyceride metabolic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
phospholipid metabolic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
apoptotic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
lysosomal transport	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
cholesterol metabolic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
cellular response to starvation	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
regulation of signaling receptor activity	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of low-density lipoprotein particle clearance	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
protein autoprocessing	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
neurogenesis	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
neuron differentiation	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
low-density lipoprotein particle receptor catabolic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
positive regulation of low-density lipoprotein particle receptor catabolic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
cellular response to insulin stimulus	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
lipoprotein metabolic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
cholesterol homeostasis	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
regulation of neuron apoptotic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
positive regulation of neuron apoptotic process	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of low-density lipoprotein particle receptor binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of low-density lipoprotein receptor activity	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of receptor-mediated endocytosis involved in cholesterol transport	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
negative regulation of sodium ion transmembrane transporter activity	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
chromatin remodeling	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
peptidyl-threonine phosphorylation	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
peptidyl-serine phosphorylation	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
visual perception	Myosin-IIIa	Homo sapiens (human)
sensory perception of sound	Myosin-IIIa	Homo sapiens (human)
protein autophosphorylation	Myosin-IIIa	Homo sapiens (human)
cochlea morphogenesis	Myosin-IIIa	Homo sapiens (human)
regulation of actin filament length	Myosin-IIIa	Homo sapiens (human)
positive regulation of filopodium assembly	Myosin-IIIa	Homo sapiens (human)
peptidyl-serine phosphorylation	Myosin-IIIa	Homo sapiens (human)
regulation of cell cycle process	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
regulation of cell cycle process	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
mitotic intra-S DNA damage checkpoint signaling	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
regulation of mitotic cell cycle phase transition	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
protein phosphorylation	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
ubiquinone biosynthetic process	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
phosphorylation	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
regulation of autophagy	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
positive regulation of autophagosome assembly	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 15	Homo sapiens (human)
regulation of COPII vesicle coating	Mitogen-activated protein kinase 15	Homo sapiens (human)
DNA damage response	Mitogen-activated protein kinase 15	Homo sapiens (human)
endoplasmic reticulum organization	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of cell population proliferation	Mitogen-activated protein kinase 15	Homo sapiens (human)
regulation of autophagy	Mitogen-activated protein kinase 15	Homo sapiens (human)
negative regulation of cell migration	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
dopamine uptake	Mitogen-activated protein kinase 15	Homo sapiens (human)
regulation of cilium assembly	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein localization to ciliary transition zone	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of metaphase/anaphase transition of meiosis I	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of spindle assembly	Mitogen-activated protein kinase 15	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 15	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
response to ionizing radiation	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
response to UV	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
neurotransmitter secretion	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
associative learning	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
response to UV	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
regulation of neuron projection development	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
neuron differentiation	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
regulation of synaptic plasticity	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
centrosome duplication	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
microtubule cytoskeleton organization involved in establishment of planar polarity	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
synaptic vesicle cycle	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
regulation of synaptic vesicle clustering	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
regulation of translational initiation by eIF2 alpha phosphorylation	Serine/threonine-protein kinase 35	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
cellular response to potassium ion	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
spindle assembly	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of telomerase activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of telomere capping	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
signal transduction	Rhodopsin kinase GRK7	Homo sapiens (human)
visual perception	Rhodopsin kinase GRK7	Homo sapiens (human)
regulation of opsin-mediated signaling pathway	Rhodopsin kinase GRK7	Homo sapiens (human)
protein autophosphorylation	Rhodopsin kinase GRK7	Homo sapiens (human)
regulation of signal transduction	Rhodopsin kinase GRK7	Homo sapiens (human)
protein phosphorylation	Rhodopsin kinase GRK7	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 32A	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 32A	Homo sapiens (human)
visual perception	Myosin-IIIb	Homo sapiens (human)
sensory perception of sound	Myosin-IIIb	Homo sapiens (human)
cochlea morphogenesis	Myosin-IIIb	Homo sapiens (human)
regulation of actin filament length	Myosin-IIIb	Homo sapiens (human)
peptidyl-serine phosphorylation	Myosin-IIIb	Homo sapiens (human)
positive regulation of filopodium assembly	Myosin-IIIb	Homo sapiens (human)
spliceosomal complex assembly	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
positive regulation of myeloid dendritic cell cytokine production	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
double-strand break repair	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
tRNA splicing, via endonucleolytic cleavage and ligation	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
regulation of translational initiation	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
DNA duplex unwinding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
response to exogenous dsRNA	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
innate immune response	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
defense response to virus	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nucleic acid metabolic process	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
protein localization to cytoplasmic stress granule	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
protein phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
DNA damage response	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
smoothened signaling pathway	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
negative regulation of calcineurin-NFAT signaling cascade	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase-like 2	Homo sapiens (human)
sex differentiation	Cyclin-dependent kinase-like 2	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase-like 2	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase-like 2	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
cell population proliferation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
positive regulation of MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
cellular response to phorbol 13-acetate 12-myristate	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
regulation of cell migration	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
regulation of cell population proliferation	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
protein phosphorylation	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
ubiquinone biosynthetic process	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
cerebellar Purkinje cell layer morphogenesis	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Aurora kinase B	Homo sapiens (human)
mitotic cell cycle	Aurora kinase B	Homo sapiens (human)
mitotic cytokinesis	Aurora kinase B	Homo sapiens (human)
negative regulation of B cell apoptotic process	Aurora kinase B	Homo sapiens (human)
protein phosphorylation	Aurora kinase B	Homo sapiens (human)
spindle organization	Aurora kinase B	Homo sapiens (human)
attachment of spindle microtubules to kinetochore	Aurora kinase B	Homo sapiens (human)
abscission	Aurora kinase B	Homo sapiens (human)
negative regulation of protein binding	Aurora kinase B	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Aurora kinase B	Homo sapiens (human)
negative regulation of cytokinesis	Aurora kinase B	Homo sapiens (human)
positive regulation of cytokinesis	Aurora kinase B	Homo sapiens (human)
protein localization to kinetochore	Aurora kinase B	Homo sapiens (human)
cellular response to UV	Aurora kinase B	Homo sapiens (human)
cleavage furrow formation	Aurora kinase B	Homo sapiens (human)
post-translational protein modification	Aurora kinase B	Homo sapiens (human)
cell cycle G2/M phase transition	Aurora kinase B	Homo sapiens (human)
mitotic cytokinesis checkpoint signaling	Aurora kinase B	Homo sapiens (human)
negative regulation of innate immune response	Aurora kinase B	Homo sapiens (human)
protein autophosphorylation	Aurora kinase B	Homo sapiens (human)
mitotic spindle midzone assembly	Aurora kinase B	Homo sapiens (human)
positive regulation of telomerase activity	Aurora kinase B	Homo sapiens (human)
regulation of chromosome segregation	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic sister chromatid segregation	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic cell cycle spindle assembly checkpoint	Aurora kinase B	Homo sapiens (human)
mitotic spindle assembly	Aurora kinase B	Homo sapiens (human)
negative regulation of cGAS/STING signaling pathway	Aurora kinase B	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic sister chromatid separation	Aurora kinase B	Homo sapiens (human)
positive regulation of attachment of mitotic spindle microtubules to kinetochore	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic cytokinesis	Aurora kinase B	Homo sapiens (human)
positive regulation of telomere capping	Aurora kinase B	Homo sapiens (human)
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	Aurora kinase B	Homo sapiens (human)
mitotic spindle organization	Aurora kinase B	Homo sapiens (human)
regulation of cytokinesis	Aurora kinase B	Homo sapiens (human)
microtubule cytoskeleton organization	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of cell cycle	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule cytoskeleton organization	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule bundle formation	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein phosphorylation	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
nervous system development	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of programmed cell death	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cilium organization	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of cilium assembly	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
regulation of centrosome cycle	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cell division	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of protein localization to centrosome	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
intracellular signal transduction	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 15	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 15	Homo sapiens (human)
protein phosphorylation	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
regulation of respiratory gaseous exchange	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of glycogen biosynthetic process	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of translation	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
protein autophosphorylation	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
regulation of glucagon secretion	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
energy homeostasis	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
MAPK cascade	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
calcium-mediated signaling	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
cellular response to reactive oxygen species	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
regulation of protein kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
CAMKK-AMPK signaling cascade	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
positive regulation of autophagy of mitochondrion	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein phosphorylation	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
tRNA processing	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
tRNA threonylcarbamoyladenosine metabolic process	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein phosphorylation	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
spermatogenesis	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
actin cytoskeleton organization	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
focal adhesion assembly	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
protein phosphorylation	SRSF protein kinase 1	Homo sapiens (human)
chromosome segregation	SRSF protein kinase 1	Homo sapiens (human)
RNA splicing	SRSF protein kinase 1	Homo sapiens (human)
sperm DNA condensation	SRSF protein kinase 1	Homo sapiens (human)
intracellular signal transduction	SRSF protein kinase 1	Homo sapiens (human)
positive regulation of viral genome replication	SRSF protein kinase 1	Homo sapiens (human)
negative regulation of viral genome replication	SRSF protein kinase 1	Homo sapiens (human)
innate immune response	SRSF protein kinase 1	Homo sapiens (human)
regulation of mRNA splicing, via spliceosome	SRSF protein kinase 1	Homo sapiens (human)
regulation of mRNA processing	SRSF protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	SRSF protein kinase 1	Homo sapiens (human)
spliceosomal complex assembly	SRSF protein kinase 1	Homo sapiens (human)
regulation of cyclin-dependent protein serine/threonine kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
mitotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
regulation of mitotic nuclear division	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
negative regulation of G2/M transition of mitotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein phosphorylation	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
negative regulation of G2/MI transition of meiotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
meiotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
response to ischemia	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
response to endoplasmic reticulum stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
neuron intrinsic apoptotic signaling pathway in response to oxidative stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
innate immune response	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of myoblast differentiation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of protein kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of DNA-templated transcription	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
neuron apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to hydrogen peroxide	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
endothelial cell apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
apoptotic signaling pathway	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
programmed necrotic cell death	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to reactive nitrogen species	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
glycerophospholipid metabolic process	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
phosphatidylinositol biosynthetic process	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
phagocytosis	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
signal transduction	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
phospholipid biosynthetic process	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
fibroblast migration	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
cell migration	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
actin cytoskeleton organization	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
keratinocyte differentiation	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
focal adhesion assembly	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
cell chemotaxis	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
protein localization to plasma membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
activation of GTPase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
ruffle assembly	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
blood vessel development	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of cell proliferation in bone marrow	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
negative regulation of cellular senescence	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
acute inflammatory response	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
phagocytosis	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
negative regulation of cell population proliferation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
regulation of eIF2 alpha phosphorylation by heme	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
macrophage differentiation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
negative regulation of translational initiation by iron	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protoporphyrinogen IX metabolic process	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein autophosphorylation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
negative regulation of hemoglobin biosynthetic process	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
establishment of localization in cell	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
multicellular organismal-level iron ion homeostasis	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
integrated stress response signaling	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
HRI-mediated signaling	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
positive regulation of mitophagy	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
response to iron ion starvation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
regulation of translational initiation by eIF2 alpha phosphorylation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
maturation of SSU-rRNA	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
ribosomal small subunit biogenesis	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
positive regulation of rRNA processing	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
regulation of translation	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein phosphorylation	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
intracellular signal transduction	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein autophosphorylation	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
regulation of mitotic metaphase/anaphase transition	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
maturation of SSU-rRNA	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
ribosomal small subunit biogenesis	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
positive regulation of ribosomal small subunit export from nucleus	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
positive regulation of rRNA processing	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
positive regulation of apoptotic process	Cyclin-dependent kinase 19	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 19	Homo sapiens (human)
cellular response to lipopolysaccharide	Cyclin-dependent kinase 19	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 19	Homo sapiens (human)
response to toxic substance	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
protein tetramerization	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
calcium ion transmembrane transport	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
metal ion transport	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
monoatomic cation transmembrane transport	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
protein phosphorylation	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
spermatid development	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 33	Homo sapiens (human)
mitotic DNA damage checkpoint signaling	Serine/threonine-protein kinase 33	Homo sapiens (human)
regulation of cyclin-dependent protein serine/threonine kinase activity	Nucleolar GTP-binding protein 1	Homo sapiens (human)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Nucleolar GTP-binding protein 1	Homo sapiens (human)
osteoblast differentiation	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of DNA replication	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of cell population proliferation	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of cell-cell adhesion	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of cell migration	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of protein ubiquitination	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of collagen binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
ribosomal large subunit biogenesis	Nucleolar GTP-binding protein 1	Homo sapiens (human)
protein stabilization	Nucleolar GTP-binding protein 1	Homo sapiens (human)
angiogenesis	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Serine/threonine-protein kinase D2	Homo sapiens (human)
adaptive immune response	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
cell adhesion	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of endothelial cell migration	Serine/threonine-protein kinase D2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of interleukin-2 production	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of interleukin-8 production	Serine/threonine-protein kinase D2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of fibroblast growth factor receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of cell adhesion	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
T cell receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of T cell receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
endothelial tube morphogenesis	Serine/threonine-protein kinase D2	Homo sapiens (human)
regulation of T cell apoptotic process	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Serine/threonine-protein kinase D2	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
protein phosphorylation	NUAK family SNF1-like kinase 2	Homo sapiens (human)
apoptotic process	NUAK family SNF1-like kinase 2	Homo sapiens (human)
actin cytoskeleton organization	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein localization to nucleus	NUAK family SNF1-like kinase 2	Homo sapiens (human)
regulation of hippo signaling	NUAK family SNF1-like kinase 2	Homo sapiens (human)
cellular response to glucose starvation	NUAK family SNF1-like kinase 2	Homo sapiens (human)
negative regulation of apoptotic process	NUAK family SNF1-like kinase 2	Homo sapiens (human)
rRNA modification	RNA cytidine acetyltransferase	Homo sapiens (human)
regulation of translation	RNA cytidine acetyltransferase	Homo sapiens (human)
protein acetylation	RNA cytidine acetyltransferase	Homo sapiens (human)
regulation of centrosome duplication	RNA cytidine acetyltransferase	Homo sapiens (human)
negative regulation of telomere maintenance via telomerase	RNA cytidine acetyltransferase	Homo sapiens (human)
ribosomal small subunit biogenesis	RNA cytidine acetyltransferase	Homo sapiens (human)
positive regulation of translation	RNA cytidine acetyltransferase	Homo sapiens (human)
tRNA acetylation	RNA cytidine acetyltransferase	Homo sapiens (human)
rRNA acetylation involved in maturation of SSU-rRNA	RNA cytidine acetyltransferase	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
regulation of insulin receptor signaling pathway	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
striated muscle contraction	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
neuromuscular synaptic transmission	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
positive regulation of gene expression	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
skeletal muscle satellite cell differentiation	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
peptidyl-threonine phosphorylation	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
regulation of muscle filament sliding	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
skeletal muscle cell differentiation	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
protein autophosphorylation	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
cardiac muscle tissue morphogenesis	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
cardiac muscle contraction	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
apoptotic process	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell migration	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cytoplasmic microtubule organization	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
regulation of apoptotic process	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein autophosphorylation	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
regulation of focal adhesion assembly	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
DNA repair	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
positive regulation of JUN kinase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
negative regulation of JNK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
neuron projection morphogenesis	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
eye development	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
respiratory system process	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein phosphorylation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
adult walking behavior	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
cell population proliferation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of cell population proliferation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
anterior/posterior pattern specification	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
gene expression	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
retina layer formation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
neuron differentiation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
erythrocyte differentiation	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of transforming growth factor beta receptor signaling pathway	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
negative regulation of BMP signaling pathway	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
PML body organization	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
thyroid gland development	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of protein binding	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
epigenetic regulation of gene expression	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
negative regulation of neuron apoptotic process	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of angiogenesis	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of JNK cascade	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
embryonic camera-type eye morphogenesis	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
voluntary musculoskeletal movement	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
neuron apoptotic process	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
regulation of cell cycle	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
embryonic retina morphogenesis in camera-type eye	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
lens induction in camera-type eye	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
SMAD protein signal transduction	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
lung morphogenesis	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
iris morphogenesis	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
cellular response to hypoxia	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
intrinsic apoptotic signaling pathway	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
negative regulation of ubiquitin-dependent protein catabolic process	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
smoothened signaling pathway	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
negative regulation of signal transduction	Tyrosine-protein kinase Srms	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Srms	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Tyrosine-protein kinase Srms	Homo sapiens (human)
positive regulation of TORC1 signaling	Tyrosine-protein kinase Srms	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Srms	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Srms	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Srms	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Srms	Homo sapiens (human)
protein phosphorylation	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
apoptotic process	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
mRNA transcription	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
peptidyl-serine phosphorylation	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
peptidyl-threonine phosphorylation	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
negative regulation of apoptotic process	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
negative regulation of JUN kinase activity	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
response to reactive oxygen species	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
response to osmotic stress	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
endomitotic cell cycle	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
response to radiation	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
cytoplasmic microtubule organization	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
regulation of cytokinesis	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
mitotic G1/S transition checkpoint signaling	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
regulation of cell division	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
Golgi disassembly	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
positive regulation of intracellular protein transport	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
positive regulation of chaperone-mediated autophagy	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
mitotic spindle organization	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
dTTP catabolic process	dCTP pyrophosphatase 1	Homo sapiens (human)
dCTP catabolic process	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleoside triphosphate catabolic process	dCTP pyrophosphatase 1	Homo sapiens (human)
DNA protection	dCTP pyrophosphatase 1	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK4	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity protein kinase CLK4	Homo sapiens (human)
regulation of translation	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein phosphorylation	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cell surface receptor signaling pathway	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
hemopoiesis	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
intracellular signal transduction	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to arsenic-containing substance	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligand	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein autophosphorylation	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
mitotic spindle organization	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
chromosome segregation	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
mitotic nuclear membrane disassembly	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
regulation of mitotic metaphase/anaphase transition	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
spindle assembly	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
regulation of cellular senescence	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform gamma-1	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform gamma-1	Homo sapiens (human)
signal transduction	Casein kinase I isoform gamma-1	Homo sapiens (human)
endocytosis	Casein kinase I isoform gamma-1	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform gamma-1	Homo sapiens (human)
regulation of DNA-templated transcription	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
learning	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
memory	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
locomotory behavior	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
neuron projection arborization	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
neuron projection extension	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein phosphorylation	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
myeloid cell differentiation	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
inner cell mass cell fate commitment	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
inner cell mass cellular morphogenesis	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
protein localization	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
hormone-mediated signaling pathway	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
regulation of transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
keratinocyte differentiation	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
negative regulation of cyclin-dependent protein serine/threonine kinase activity	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
canonical Wnt signaling pathway	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
negative regulation of protein localization to nucleus	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
regulation of organ growth	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
epithelial cilium movement involved in extracellular fluid movement	Serine/threonine-protein kinase 36	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 36	Homo sapiens (human)
smoothened signaling pathway	Serine/threonine-protein kinase 36	Homo sapiens (human)
brain development	Serine/threonine-protein kinase 36	Homo sapiens (human)
post-embryonic development	Serine/threonine-protein kinase 36	Homo sapiens (human)
axoneme assembly	Serine/threonine-protein kinase 36	Homo sapiens (human)
positive regulation of smoothened signaling pathway	Serine/threonine-protein kinase 36	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase 36	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase 36	Homo sapiens (human)
translation	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
phenylalanyl-tRNA aminoacylation	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
protein heterotetramerization	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
tRNA aminoacylation for protein translation	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
aminoacyl-tRNA metabolism involved in translational fidelity	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
isoleucyl-tRNA aminoacylation	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
mitochondrial translation	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
positive regulation of Notch signaling pathway	BMP-2-inducible protein kinase	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	BMP-2-inducible protein kinase	Homo sapiens (human)
regulation of bone mineralization	BMP-2-inducible protein kinase	Homo sapiens (human)
ATP metabolic process	Obg-like ATPase 1	Homo sapiens (human)
ribosomal large subunit assembly	Midasin	Homo sapiens (human)
ribosomal large subunit export from nucleus	Midasin	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
neutrophil mediated immunity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
JNK cascade	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
toll-like receptor 9 signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
interleukin-33-mediated signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
innate immune response	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
neutrophil migration	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
Toll signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cellular response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
intracellular signal transduction	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 32B	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 32B	Homo sapiens (human)
positive regulation of programmed cell death	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
GCN2-mediated signaling	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
pyroptosis	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
DNA damage checkpoint signaling	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
inflammatory response	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytoskeleton organization	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cell death	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cell differentiation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
embryonic digit morphogenesis	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
limb development	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cellular response to gamma radiation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cellular response to UV-B	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
positive regulation of mitotic DNA damage checkpoint	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
regulation of mitotic metaphase/anaphase transition	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
chromosome segregation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
transcription by RNA polymerase II	Cyclin-dependent kinase 12	Homo sapiens (human)
mRNA processing	Cyclin-dependent kinase 12	Homo sapiens (human)
RNA splicing	Cyclin-dependent kinase 12	Homo sapiens (human)
positive regulation of transcription elongation by RNA polymerase II	Cyclin-dependent kinase 12	Homo sapiens (human)
regulation of MAP kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 12	Homo sapiens (human)
protein autophosphorylation	Cyclin-dependent kinase 12	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 12	Homo sapiens (human)
negative regulation of stem cell differentiation	Cyclin-dependent kinase 12	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 12	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
mitotic spindle organization	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
Ras protein signal transduction	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
memory	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
negative regulation of angiogenesis	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
Rap protein signal transduction	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
positive regulation of protein catabolic process	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
regulation of centriole replication	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
regulation of synaptic plasticity	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
long-term synaptic potentiation	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
long-term synaptic depression	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
negative regulation of apoptotic process in bone marrow cell	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
negative regulation of cellular senescence	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
aerobic respiration	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
negative regulation of cell growth	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial respiratory chain complex I assembly	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cellular response to interferon-beta	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
proton motive force-driven mitochondrial ATP synthesis	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
protein insertion into mitochondrial inner membrane	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
positive regulation of protein catabolic process	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
negative regulation of DNA-templated transcription	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cellular response to retinoic acid	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
reactive oxygen species metabolic process	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
apoptotic signaling pathway	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
extrinsic apoptotic signaling pathway	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
positive regulation of execution phase of apoptosis	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
positive regulation of gene expression	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
negative regulation of gene expression	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
neuron migration	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
negative regulation of epithelial to mesenchymal transition	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
regulation of neuron projection development	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
Wnt signaling pathway	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
regulation of dendrite development	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
establishment of mitochondrion localization	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
negative regulation of cell population proliferation	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
apoptotic mitochondrial changes	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
response to virus	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
macroautophagy	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
positive regulation of macroautophagy	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
learning	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
memory	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
locomotory behavior	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
cell population proliferation	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 26	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 26	Homo sapiens (human)
cellular response to starvation	Serine/threonine-protein kinase 26	Homo sapiens (human)
microvillus assembly	Serine/threonine-protein kinase 26	Homo sapiens (human)
negative regulation of cell migration	Serine/threonine-protein kinase 26	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase 26	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 26	Homo sapiens (human)
regulation of apoptotic process	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 26	Homo sapiens (human)
DNA damage checkpoint signaling	eIF-2-alpha kinase GCN2	Homo sapiens (human)
positive regulation of defense response to virus by host	eIF-2-alpha kinase GCN2	Homo sapiens (human)
adaptive immune response	eIF-2-alpha kinase GCN2	Homo sapiens (human)
T cell activation involved in immune response	eIF-2-alpha kinase GCN2	Homo sapiens (human)
positive regulation of adaptive immune response	eIF-2-alpha kinase GCN2	Homo sapiens (human)
regulation of translational initiation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
protein phosphorylation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
learning	eIF-2-alpha kinase GCN2	Homo sapiens (human)
long-term memory	eIF-2-alpha kinase GCN2	Homo sapiens (human)
regulation of translational initiation by eIF2 alpha phosphorylation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
viral translation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
negative regulation of translational initiation in response to stress	eIF-2-alpha kinase GCN2	Homo sapiens (human)
negative regulation of CREB transcription factor activity	eIF-2-alpha kinase GCN2	Homo sapiens (human)
cellular response to amino acid starvation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
cellular response to UV	eIF-2-alpha kinase GCN2	Homo sapiens (human)
eiF2alpha phosphorylation in response to endoplasmic reticulum stress	eIF-2-alpha kinase GCN2	Homo sapiens (human)
negative regulation by host of viral genome replication	eIF-2-alpha kinase GCN2	Homo sapiens (human)
negative regulation of neuron differentiation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
negative regulation of translational initiation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
protein autophosphorylation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
defense response to virus	eIF-2-alpha kinase GCN2	Homo sapiens (human)
regulation of feeding behavior	eIF-2-alpha kinase GCN2	Homo sapiens (human)
cellular response to cold	eIF-2-alpha kinase GCN2	Homo sapiens (human)
positive regulation of translational initiation in response to starvation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
GCN2-mediated signaling	eIF-2-alpha kinase GCN2	Homo sapiens (human)
positive regulation of long-term synaptic potentiation	eIF-2-alpha kinase GCN2	Homo sapiens (human)
neuron projection extension	eIF-2-alpha kinase GCN2	Homo sapiens (human)
negative regulation of cytoplasmic translational initiation in response to stress	eIF-2-alpha kinase GCN2	Homo sapiens (human)
tricarboxylic acid cycle	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate metabolic process	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinyl-CoA pathway	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinyl-CoA catabolic process	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinyl-CoA metabolic process	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase NLK	Homo sapiens (human)
regulation of DNA-templated transcription	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase NLK	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase NLK	Homo sapiens (human)
Wnt signaling pathway, calcium modulating pathway	Serine/threonine-protein kinase NLK	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase NLK	Homo sapiens (human)
negative regulation of Wnt signaling pathway	Serine/threonine-protein kinase NLK	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase NLK	Homo sapiens (human)
cellular response to osmotic stress	Serine/threonine-protein kinase NLK	Homo sapiens (human)
negative regulation of TORC1 signaling	Serine/threonine-protein kinase NLK	Homo sapiens (human)
positive regulation of receptor signaling pathway via STAT	Serine/threonine-protein kinase NLK	Homo sapiens (human)
lysosome organization	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
phosphatidylinositol biosynthetic process	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
receptor-mediated endocytosis	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
signal transduction	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
inner ear development	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 17A	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 17A	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 17A	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase 17A	Homo sapiens (human)
positive regulation of fibroblast apoptotic process	Serine/threonine-protein kinase 17A	Homo sapiens (human)
regulation of reactive oxygen species metabolic process	Serine/threonine-protein kinase 17A	Homo sapiens (human)
response to dietary excess	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
protein phosphorylation	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cell volume homeostasis	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
inflammatory response	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
signal transduction	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
regulation of blood pressure	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
positive regulation of T cell chemotaxis	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
peptidyl-threonine phosphorylation	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
intracellular chloride ion homeostasis	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
positive regulation of ion transmembrane transporter activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
intracellular signal transduction	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
sodium ion transmembrane transport	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cellular response to potassium ion	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
maintenance of lens transparency	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
chemokine (C-X-C motif) ligand 12 signaling pathway	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
macrophage activation	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
positive regulation of potassium ion transport	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
protein autophosphorylation	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
regulation of inflammatory response	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
renal sodium ion absorption	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cellular hyperosmotic response	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cellular hypotonic response	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
negative regulation of pancreatic juice secretion	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
positive regulation of p38MAPK cascade	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
negative regulation of potassium ion transmembrane transporter activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
negative regulation of potassium ion transmembrane transport	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
response to aldosterone	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
negative regulation of creatine transmembrane transporter activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cellular response to chemokine	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
negative regulation of sodium ion transmembrane transporter activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
biological_process	Ephrin type-A receptor 6	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 6	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 6	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 6	Homo sapiens (human)
glycogen metabolic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of glycolytic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
negative regulation of protein kinase activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
ATP biosynthetic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
sterol biosynthetic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of fatty acid metabolic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
intracellular signal transduction	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
positive regulation of protein kinase activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of fatty acid oxidation	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of glucose import	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of catalytic activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
activation of innate immune response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytoplasmic pattern recognition receptor signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
inflammatory response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
response to virus	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
negative regulation of gene expression	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of macroautophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
regulation of type I interferon production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of type I interferon production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of interferon-alpha production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of interferon-beta production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
dendritic cell proliferation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
innate immune response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
defense response to Gram-positive bacterium	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
defense response to virus	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
type I interferon-mediated signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of type I interferon-mediated signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
antiviral innate immune response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cGAS/STING signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
negative regulation of TORC1 signaling	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of TORC1 signaling	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of xenophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
macroautophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of non-motile cilium assembly	Septin-9	Homo sapiens (human)
protein localization	Septin-9	Homo sapiens (human)
cytoskeleton-dependent cytokinesis	Septin-9	Homo sapiens (human)
protein phosphorylation	Death-associated protein kinase 2	Homo sapiens (human)
apoptotic process	Death-associated protein kinase 2	Homo sapiens (human)
regulation of autophagy	Death-associated protein kinase 2	Homo sapiens (human)
intracellular signal transduction	Death-associated protein kinase 2	Homo sapiens (human)
regulation of apoptotic process	Death-associated protein kinase 2	Homo sapiens (human)
anoikis	Death-associated protein kinase 2	Homo sapiens (human)
protein autophosphorylation	Death-associated protein kinase 2	Homo sapiens (human)
positive regulation of neutrophil chemotaxis	Death-associated protein kinase 2	Homo sapiens (human)
positive regulation of eosinophil chemotaxis	Death-associated protein kinase 2	Homo sapiens (human)
regulation of intrinsic apoptotic signaling pathway	Death-associated protein kinase 2	Homo sapiens (human)
positive regulation of apoptotic process	Death-associated protein kinase 2	Homo sapiens (human)
potassium ion transport	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
protein homooligomerization	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
membrane repolarization	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
membrane repolarization during cardiac muscle cell action potential	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
membrane repolarization during ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
ventricular cardiac muscle cell membrane repolarization	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
action potential	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
central nervous system development	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
negative regulation of embryonic development	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
negative regulation of mesoderm development	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
positive regulation of protein phosphorylation	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein phosphorylation	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoskeleton organization	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
response to organonitrogen compound	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
Wnt signaling pathway	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
microvillus assembly	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
actin cytoskeleton organization	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
intracellular signal transduction	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
positive regulation of JNK cascade	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein autophosphorylation	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
regulation of dendrite morphogenesis	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein localization to plasma membrane	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
neuron projection morphogenesis	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
regulation of MAPK cascade	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
MAPK cascade	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
chromatin organization	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
intracellular protein transport	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
regulation of chromatin organization	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
chromosome segregation	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein targeting to membrane	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
regulation of cell shape	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of protein autophosphorylation	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
activation of protein kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of MAPK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
focal adhesion assembly	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
stress-activated MAPK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
basal dendrite morphogenesis	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
basal dendrite arborization	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 14	Homo sapiens (human)
protein autophosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
signal transduction	ALK tyrosine kinase receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	ALK tyrosine kinase receptor	Homo sapiens (human)
phosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
hippocampus development	ALK tyrosine kinase receptor	Homo sapiens (human)
adult behavior	ALK tyrosine kinase receptor	Homo sapiens (human)
swimming behavior	ALK tyrosine kinase receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of apoptotic process	ALK tyrosine kinase receptor	Homo sapiens (human)
protein autophosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
neuron development	ALK tyrosine kinase receptor	Homo sapiens (human)
negative regulation of lipid catabolic process	ALK tyrosine kinase receptor	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of dopamine receptor signaling pathway	ALK tyrosine kinase receptor	Homo sapiens (human)
response to environmental enrichment	ALK tyrosine kinase receptor	Homo sapiens (human)
energy homeostasis	ALK tyrosine kinase receptor	Homo sapiens (human)
positive regulation of dendrite development	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of neuron differentiation	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of cell population proliferation	ALK tyrosine kinase receptor	Homo sapiens (human)
multicellular organism development	ALK tyrosine kinase receptor	Homo sapiens (human)
positive regulation of kinase activity	ALK tyrosine kinase receptor	Homo sapiens (human)
lipid transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
organic anion transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
urate transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
biotin transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
sphingolipid biosynthetic process	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
riboflavin transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
urate metabolic process	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
transmembrane transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
transepithelial transport	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
renal urate salt excretion	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
export across plasma membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
transport across blood-brain barrier	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
cellular detoxification	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
xenobiotic transport across blood-brain barrier	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
skeletal muscle tissue development	SRSF protein kinase 3	Homo sapiens (human)
cell differentiation	SRSF protein kinase 3	Homo sapiens (human)
muscle tissue development	SRSF protein kinase 3	Homo sapiens (human)
peptidyl-serine phosphorylation	SRSF protein kinase 3	Homo sapiens (human)
spliceosomal complex assembly	SRSF protein kinase 3	Homo sapiens (human)
intracellular signal transduction	SRSF protein kinase 3	Homo sapiens (human)
regulation of mRNA processing	SRSF protein kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase ICK	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intraciliary anterograde transport	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intraciliary retrograde transport	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intraciliary transport	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase ICK	Homo sapiens (human)
mitotic cell cycle	Cyclin-dependent kinase 11A	Homo sapiens (human)
regulation of cell growth	Cyclin-dependent kinase 11A	Homo sapiens (human)
regulation of DNA-templated transcription	Cyclin-dependent kinase 11A	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 11A	Homo sapiens (human)
apoptotic process	Cyclin-dependent kinase 11A	Homo sapiens (human)
regulation of mRNA processing	Cyclin-dependent kinase 11A	Homo sapiens (human)
regulation of mitotic cell cycle	Cyclin-dependent kinase 11A	Homo sapiens (human)
protein phosphorylation	Aurora kinase C	Homo sapiens (human)
attachment of spindle microtubules to kinetochore	Aurora kinase C	Homo sapiens (human)
positive regulation of cytokinesis	Aurora kinase C	Homo sapiens (human)
mitotic spindle midzone assembly	Aurora kinase C	Homo sapiens (human)
cell division	Aurora kinase C	Homo sapiens (human)
meiotic cell cycle	Aurora kinase C	Homo sapiens (human)
regulation of cytokinesis	Aurora kinase C	Homo sapiens (human)
mitotic spindle organization	Aurora kinase C	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
response to ischemia	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
calcium ion transport	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
cellular response to interferon-beta	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
angiotensin-activated signaling pathway	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
regulation of neurotransmitter secretion	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
regulation of neuronal synaptic plasticity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
negative regulation of hydrolase activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
positive regulation of calcium ion transport	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
dendritic spine development	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
cellular response to type II interferon	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
regulation of mitochondrial membrane permeability involved in apoptotic process	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
peptidyl-threonine autophosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
regulation of endocannabinoid signaling pathway	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
regulation of neuron migration	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
mitochondrial genome maintenance	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endothelial cell proliferation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of TOR signaling	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of angiogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell size	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
brain morphogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
homeostasis of number of cells within a tissue	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of vascular endothelial cell proliferation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of artery morphogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cellular senescence	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
response to bacterium	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
one-carbon metabolic process	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
negative regulation of autophagy	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
regulation of cellular component organization	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
postsynapse organization	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
protein phosphorylation	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
cytoskeleton organization	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
brain development	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
intracellular signal transduction	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
positive regulation of TORC1 signaling	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
positive regulation of TORC2 signaling	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
regulation of alternative mRNA splicing, via spliceosome	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear-transcribed mRNA catabolic process	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
mRNA processing	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
circadian rhythm	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
RNA splicing	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of circadian rhythm	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of mRNA splicing, via spliceosome	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
mRNA stabilization	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
DNA repair	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
myoblast fusion	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
adipose tissue development	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
peptidyl-threonine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
regulation of T cell mediated cytotoxicity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of adaptive immune response	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of phosphatase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
activation of protein kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of type II interferon production	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
T cell differentiation in thymus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein modification process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
non-canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of apoptotic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
T cell homeostasis	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of activated T cell proliferation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein autophosphorylation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
lymph node development	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
spleen development	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
thymus development	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
defense response to virus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of necroptotic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of activation-induced cell death of T cells	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
necroptotic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cellular response to hydrogen peroxide	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
reactive oxygen species metabolic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
programmed necrotic cell death	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
necroptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
execution phase of necroptosis	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
amyloid fibril formation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
signal transduction	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
establishment or maintenance of cell polarity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actomyosin structure organization	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
positive regulation of cytokine production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein phosphorylation	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to virus	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
positive regulation of macrophage tolerance induction	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of macrophage cytokine production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to peptidoglycan	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of interleukin-12 production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of interleukin-6 production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of tumor necrosis factor production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of protein catabolic process	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of protein-containing complex disassembly	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
regulation of protein-containing complex disassembly	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to exogenous dsRNA	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of MAP kinase activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of innate immune response	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to interleukin-1	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
Toll signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cellular response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
intracellular signal transduction	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 24	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase 24	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Serine/threonine-protein kinase 24	Homo sapiens (human)
cellular response to starvation	Serine/threonine-protein kinase 24	Homo sapiens (human)
negative regulation of cell migration	Serine/threonine-protein kinase 24	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 24	Homo sapiens (human)
regulation of axon regeneration	Serine/threonine-protein kinase 24	Homo sapiens (human)
positive regulation of axon regeneration	Serine/threonine-protein kinase 24	Homo sapiens (human)
execution phase of apoptosis	Serine/threonine-protein kinase 24	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform gamma-3	Homo sapiens (human)
protein modification process	Casein kinase I isoform gamma-3	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform gamma-3	Homo sapiens (human)
signal transduction	Casein kinase I isoform gamma-3	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform gamma-3	Homo sapiens (human)
endocytosis	Casein kinase I isoform gamma-3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
placenta development	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
response to UV-C	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
regulation of gene expression	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
male germ-line sex determination	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
chorionic trophoblast cell differentiation	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (618)

Process	via Protein(s)	Taxonomy
protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
transmembrane signaling receptor activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
protein binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
ATP binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
BMP binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
SMAD binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
metal ion binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
BMP receptor activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
amyloid-beta binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
steroid binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
protein binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
heme binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
protein homodimerization activity	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
metal ion binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
protein kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein binding	Cell division cycle 7-related protein kinase	Homo sapiens (human)
ATP binding	Cell division cycle 7-related protein kinase	Homo sapiens (human)
kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
metal ion binding	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein serine kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
1-phosphatidylinositol-3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 25	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 25	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 25	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 25	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 25	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 25	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 25	Homo sapiens (human)
DNA binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
DNA helicase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
mRNA binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
GTPase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
transcription factor binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
poly(A) binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
eukaryotic initiation factor 4E binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ribonucleoside triphosphate phosphatase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
translation initiation factor binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA strand annealing activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
signaling adaptor activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA stem-loop binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
gamma-tubulin binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ribosomal small subunit binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
CTPase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein serine/threonine kinase activator activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cadherin binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
mRNA 5'-UTR binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein binding	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
1-phosphatidylinositol-3-kinase activity	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 3-kinase activity	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
phosphatidylinositol binding	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
magnesium ion binding	Pyridoxal kinase	Homo sapiens (human)
ATP binding	Pyridoxal kinase	Homo sapiens (human)
zinc ion binding	Pyridoxal kinase	Homo sapiens (human)
pyridoxal kinase activity	Pyridoxal kinase	Homo sapiens (human)
pyridoxal phosphate binding	Pyridoxal kinase	Homo sapiens (human)
potassium ion binding	Pyridoxal kinase	Homo sapiens (human)
sodium ion binding	Pyridoxal kinase	Homo sapiens (human)
lithium ion binding	Pyridoxal kinase	Homo sapiens (human)
protein homodimerization activity	Pyridoxal kinase	Homo sapiens (human)
transcription coactivator binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Citron Rho-interacting kinase	Homo sapiens (human)
protein binding	Citron Rho-interacting kinase	Homo sapiens (human)
ATP binding	Citron Rho-interacting kinase	Homo sapiens (human)
SH3 domain binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein kinase binding	Citron Rho-interacting kinase	Homo sapiens (human)
PDZ domain binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine/threonine kinase inhibitor activity	Citron Rho-interacting kinase	Homo sapiens (human)
metal ion binding	Citron Rho-interacting kinase	Homo sapiens (human)
scaffold protein binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine kinase activity	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
caspase binding	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
magnesium ion binding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
MAP kinase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
JUN kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
enzyme binding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
protein kinase binding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
protein phosphatase binding	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
molecular function activator activity	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein domain specific binding	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
histone H3T11 kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein serine/threonine kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein binding	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
ATP binding	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
IkappaB kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein kinase binding	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
identical protein binding	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein homodimerization activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein heterodimerization activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
scaffold protein binding	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
protein serine kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
transferrin receptor binding	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
guanylate kinase activity	Peripheral plasma membrane protein CASK	Homo sapiens (human)
protein serine/threonine kinase activity	Peripheral plasma membrane protein CASK	Homo sapiens (human)
protein binding	Peripheral plasma membrane protein CASK	Homo sapiens (human)
calmodulin binding	Peripheral plasma membrane protein CASK	Homo sapiens (human)
ATP binding	Peripheral plasma membrane protein CASK	Homo sapiens (human)
neurexin family protein binding	Peripheral plasma membrane protein CASK	Homo sapiens (human)
protein serine kinase activity	Peripheral plasma membrane protein CASK	Homo sapiens (human)
signaling receptor binding	Peripheral plasma membrane protein CASK	Homo sapiens (human)
protein kinase activity	Aurora kinase A	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase A	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Aurora kinase A	Homo sapiens (human)
protein binding	Aurora kinase A	Homo sapiens (human)
ATP binding	Aurora kinase A	Homo sapiens (human)
protein kinase binding	Aurora kinase A	Homo sapiens (human)
ubiquitin protein ligase binding	Aurora kinase A	Homo sapiens (human)
histone H3S10 kinase activity	Aurora kinase A	Homo sapiens (human)
protein heterodimerization activity	Aurora kinase A	Homo sapiens (human)
protein serine kinase activity	Aurora kinase A	Homo sapiens (human)
molecular function activator activity	Aurora kinase A	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-G-associated kinase	Homo sapiens (human)
protein binding	Cyclin-G-associated kinase	Homo sapiens (human)
ATP binding	Cyclin-G-associated kinase	Homo sapiens (human)
cyclin binding	Cyclin-G-associated kinase	Homo sapiens (human)
protein-folding chaperone binding	Cyclin-G-associated kinase	Homo sapiens (human)
protein serine kinase activity	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin binding	Cyclin-G-associated kinase	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
protein kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein serine/threonine kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein binding	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
ATP binding	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
IkappaB kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein homodimerization activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein-containing complex binding	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein heterodimerization activity	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
scaffold protein binding	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
transferrin receptor binding	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
protein tyrosine kinase activity	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
protein binding	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
ATP binding	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
metal ion binding	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
Wnt-protein binding	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
ephrin receptor activity	Ephrin type-B receptor 6	Homo sapiens (human)
protein binding	Ephrin type-B receptor 6	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 6	Homo sapiens (human)
signaling receptor activity	Ephrin type-B receptor 6	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 6	Homo sapiens (human)
FAD binding	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
flavin adenine dinucleotide binding	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
pristanoyl-CoA oxidase activity	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
fatty acid binding	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 13	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 13	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 13	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 13	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 13	Homo sapiens (human)
protein serine/threonine kinase activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
3-phosphoinositide-dependent protein kinase activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
protein binding	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
ATP binding	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
phospholipase activator activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
phospholipase binding	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
protein serine kinase activity	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
enzyme binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein serine/threonine kinase activator activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
IkappaB kinase complex binding	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
protein serine/threonine kinase activity	Death-associated protein kinase 3	Homo sapiens (human)
protein binding	Death-associated protein kinase 3	Homo sapiens (human)
ATP binding	Death-associated protein kinase 3	Homo sapiens (human)
cAMP response element binding protein binding	Death-associated protein kinase 3	Homo sapiens (human)
small GTPase binding	Death-associated protein kinase 3	Homo sapiens (human)
identical protein binding	Death-associated protein kinase 3	Homo sapiens (human)
protein homodimerization activity	Death-associated protein kinase 3	Homo sapiens (human)
leucine zipper domain binding	Death-associated protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Death-associated protein kinase 3	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
transcription coactivator binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
type II transforming growth factor beta receptor binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
receptor tyrosine kinase binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
ubiquitin protein ligase binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
histone kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
scaffold protein binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
protein serine/threonine kinase binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
DNA-binding transcription factor binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
linear polyubiquitin binding	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
protein serine/threonine kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
signaling receptor binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
ATP binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
LIM domain binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
signaling adaptor activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
identical protein binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein homodimerization activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
CARD domain binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
caspase binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
JUN kinase kinase kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 12	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 12	Homo sapiens (human)
protein kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein binding	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
ATP binding	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein serine kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
histone H2A kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
p53 binding	NUAK family SNF1-like kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	NUAK family SNF1-like kinase 1	Homo sapiens (human)
protein binding	NUAK family SNF1-like kinase 1	Homo sapiens (human)
ATP binding	NUAK family SNF1-like kinase 1	Homo sapiens (human)
metal ion binding	NUAK family SNF1-like kinase 1	Homo sapiens (human)
protein serine kinase activity	NUAK family SNF1-like kinase 1	Homo sapiens (human)
magnesium ion binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTPase activity	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
protein binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTP binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
phosphatidic acid binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTPase-dependent fusogenic activity	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane bending activity	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cardiolipin binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
microtubule binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
protein binding	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
phosphatidylinositol kinase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
growth hormone receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-12 receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
heme binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
type 1 angiotensin receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
acetylcholine receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
histone H3Y41 kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
histone binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
insulin receptor substrate binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
peptide hormone receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
metal ion binding	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
high voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
tRNA binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
RNA binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
translation initiation factor activity	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
GTPase activity	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
protein binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
GTP binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
metal ion binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
protease binding	Rho-associated protein kinase 2	Homo sapiens (human)
RNA binding	Rho-associated protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
structural molecule activity	Rho-associated protein kinase 2	Homo sapiens (human)
protein binding	Rho-associated protein kinase 2	Homo sapiens (human)
ATP binding	Rho-associated protein kinase 2	Homo sapiens (human)
small GTPase binding	Rho-associated protein kinase 2	Homo sapiens (human)
metal ion binding	Rho-associated protein kinase 2	Homo sapiens (human)
tau protein binding	Rho-associated protein kinase 2	Homo sapiens (human)
tau-protein kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
endopeptidase activator activity	Rho-associated protein kinase 2	Homo sapiens (human)
Rho-dependent protein serine/threonine kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
GTPase binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
RNA endonuclease activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
platelet-derived growth factor receptor binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
enzyme binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
Hsp70 protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
ADP binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
Hsp90 protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
unfolded protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein tyrosine kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
histone H3S10 kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
histone H3S28 kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
histone H2AS1 kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
RNA binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
RNA helicase activity	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
helicase activity	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
protein binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
ATP binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
ATP hydrolysis activity	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
identical protein binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
histone H3S10 kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
histone H3S28 kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Serine/threonine-protein kinase 16	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 16	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 16	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
1-phosphatidylinositol-3-kinase activity	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 3-kinase activity	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
phosphatidylinositol binding	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
phosphatidylinositol kinase activity	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
neurotransmitter transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
protein binding	Solute carrier family 22 member 3	Homo sapiens (human)
monoamine transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
organic anion transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
organic cation transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
spermidine transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
quaternary ammonium group transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
toxin transmembrane transporter activity	Solute carrier family 22 member 3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
MAP kinase kinase activity	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
SH3 domain binding	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase-like 5	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein binding	Cyclin-dependent kinase-like 5	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase-like 5	Homo sapiens (human)
kinase activity	Cyclin-dependent kinase-like 5	Homo sapiens (human)
small GTPase binding	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase-like 5	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 17B	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 17B	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 17B	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 17B	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 10	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 10	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 10	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 14	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 14	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 14	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 14	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 14	Homo sapiens (human)
single-stranded DNA binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
protein binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
ATP binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
ATP hydrolysis activity	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
chromatin binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
creatine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
microtubule binding	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
nuclear estrogen receptor binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cadherin binding involved in cell-cell adhesion	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
ubiquitin protein ligase binding	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
supercoiled DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
magnesium ion binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
four-way junction DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
bubble DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
transcription coactivator activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin monomer binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nicotinate-nucleotide adenylyltransferase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein kinase C binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
SH3 domain binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
syntaxin binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
manganese ion binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuropilin binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin filament binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitogen-activated protein kinase binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
proline-rich region binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
delta-catenin binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
sequence-specific double-stranded DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
protein binding	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
ATP binding	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
protein phosphatase binding	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
heme binding	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
connexin binding	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
signaling receptor binding	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
epidermal growth factor receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
virus receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
chromatin binding	Epidermal growth factor receptor	Homo sapiens (human)
double-stranded DNA binding	Epidermal growth factor receptor	Homo sapiens (human)
MAP kinase kinase kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
protein tyrosine kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
transmembrane signaling receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
integrin binding	Epidermal growth factor receptor	Homo sapiens (human)
protein binding	Epidermal growth factor receptor	Homo sapiens (human)
calmodulin binding	Epidermal growth factor receptor	Homo sapiens (human)
ATP binding	Epidermal growth factor receptor	Homo sapiens (human)
enzyme binding	Epidermal growth factor receptor	Homo sapiens (human)
kinase binding	Epidermal growth factor receptor	Homo sapiens (human)
protein kinase binding	Epidermal growth factor receptor	Homo sapiens (human)
protein phosphatase binding	Epidermal growth factor receptor	Homo sapiens (human)
protein tyrosine kinase activator activity	Epidermal growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activator activity	Epidermal growth factor receptor	Homo sapiens (human)
ubiquitin protein ligase binding	Epidermal growth factor receptor	Homo sapiens (human)
identical protein binding	Epidermal growth factor receptor	Homo sapiens (human)
cadherin binding	Epidermal growth factor receptor	Homo sapiens (human)
actin filament binding	Epidermal growth factor receptor	Homo sapiens (human)
ATPase binding	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor binding	Epidermal growth factor receptor	Homo sapiens (human)
arylesterase activity	Carbonic anhydrase 1	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 1	Homo sapiens (human)
protein binding	Carbonic anhydrase 1	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 1	Homo sapiens (human)
hydro-lyase activity	Carbonic anhydrase 1	Homo sapiens (human)
cyanamide hydratase activity	Carbonic anhydrase 1	Homo sapiens (human)
arylesterase activity	Carbonic anhydrase 2	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 2	Homo sapiens (human)
protein binding	Carbonic anhydrase 2	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 2	Homo sapiens (human)
cyanamide hydratase activity	Carbonic anhydrase 2	Homo sapiens (human)
amyloid-beta binding	Low-density lipoprotein receptor	Homo sapiens (human)
virus receptor activity	Low-density lipoprotein receptor	Homo sapiens (human)
protease binding	Low-density lipoprotein receptor	Homo sapiens (human)
low-density lipoprotein particle receptor activity	Low-density lipoprotein receptor	Homo sapiens (human)
calcium ion binding	Low-density lipoprotein receptor	Homo sapiens (human)
protein binding	Low-density lipoprotein receptor	Homo sapiens (human)
low-density lipoprotein particle binding	Low-density lipoprotein receptor	Homo sapiens (human)
very-low-density lipoprotein particle receptor activity	Low-density lipoprotein receptor	Homo sapiens (human)
clathrin heavy chain binding	Low-density lipoprotein receptor	Homo sapiens (human)
identical protein binding	Low-density lipoprotein receptor	Homo sapiens (human)
molecular adaptor activity	Low-density lipoprotein receptor	Homo sapiens (human)
lipoprotein particle binding	Low-density lipoprotein receptor	Homo sapiens (human)
protease binding	Fibronectin	Homo sapiens (human)
signaling receptor binding	Fibronectin	Homo sapiens (human)
integrin binding	Fibronectin	Homo sapiens (human)
extracellular matrix structural constituent	Fibronectin	Homo sapiens (human)
protein binding	Fibronectin	Homo sapiens (human)
collagen binding	Fibronectin	Homo sapiens (human)
heparin binding	Fibronectin	Homo sapiens (human)
peptidase activator activity	Fibronectin	Homo sapiens (human)
identical protein binding	Fibronectin	Homo sapiens (human)
proteoglycan binding	Fibronectin	Homo sapiens (human)
small GTPase binding	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
protein kinase activity	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
enzyme binding	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
identical protein binding	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
metal ion binding	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
MAP kinase kinase kinase activity	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
growth factor binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
RNA polymerase I core binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
protein tyrosine kinase activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
transmembrane signaling receptor activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
signaling receptor binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
protein binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ATP binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
coreceptor activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
receptor tyrosine kinase binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
identical protein binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ErbB-3 class receptor binding	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
protein heterodimerization activity	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
protein tyrosine kinase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
GPI-linked ephrin receptor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin p75 receptor binding	High affinity nerve growth factor receptor	Homo sapiens (human)
protein binding	High affinity nerve growth factor receptor	Homo sapiens (human)
ATP binding	High affinity nerve growth factor receptor	Homo sapiens (human)
nerve growth factor receptor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
kinase binding	High affinity nerve growth factor receptor	Homo sapiens (human)
identical protein binding	High affinity nerve growth factor receptor	Homo sapiens (human)
protein homodimerization activity	High affinity nerve growth factor receptor	Homo sapiens (human)
nerve growth factor binding	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin binding	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin receptor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
adenine nucleotide transmembrane transporter activity	ADP/ATP translocase 2	Homo sapiens (human)
RNA binding	ADP/ATP translocase 2	Homo sapiens (human)
ATP:ADP antiporter activity	ADP/ATP translocase 2	Homo sapiens (human)
protein binding	ADP/ATP translocase 2	Homo sapiens (human)
proton transmembrane transporter activity	ADP/ATP translocase 2	Homo sapiens (human)
adenine transmembrane transporter activity	ADP/ATP translocase 2	Homo sapiens (human)
oxidative phosphorylation uncoupler activity	ADP/ATP translocase 2	Homo sapiens (human)
ubiquitin protein ligase binding	ADP/ATP translocase 2	Homo sapiens (human)
chromatin binding	Protein kinase C beta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C beta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C beta type	Homo sapiens (human)
protein kinase C binding	Protein kinase C beta type	Homo sapiens (human)
calcium channel regulator activity	Protein kinase C beta type	Homo sapiens (human)
protein binding	Protein kinase C beta type	Homo sapiens (human)
ATP binding	Protein kinase C beta type	Homo sapiens (human)
zinc ion binding	Protein kinase C beta type	Homo sapiens (human)
nuclear receptor coactivator activity	Protein kinase C beta type	Homo sapiens (human)
histone H3T6 kinase activity	Protein kinase C beta type	Homo sapiens (human)
histone binding	Protein kinase C beta type	Homo sapiens (human)
nuclear androgen receptor binding	Protein kinase C beta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C beta type	Homo sapiens (human)
amyloid-beta binding	Insulin receptor	Homo sapiens (human)
protein tyrosine kinase activity	Insulin receptor	Homo sapiens (human)
insulin receptor activity	Insulin receptor	Homo sapiens (human)
insulin-like growth factor receptor binding	Insulin receptor	Homo sapiens (human)
protein binding	Insulin receptor	Homo sapiens (human)
ATP binding	Insulin receptor	Homo sapiens (human)
GTP binding	Insulin receptor	Homo sapiens (human)
protein domain specific binding	Insulin receptor	Homo sapiens (human)
insulin-like growth factor I binding	Insulin receptor	Homo sapiens (human)
insulin-like growth factor II binding	Insulin receptor	Homo sapiens (human)
cargo receptor activity	Insulin receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Insulin receptor	Homo sapiens (human)
insulin binding	Insulin receptor	Homo sapiens (human)
insulin receptor substrate binding	Insulin receptor	Homo sapiens (human)
protein-containing complex binding	Insulin receptor	Homo sapiens (human)
PTB domain binding	Insulin receptor	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein serine/threonine phosphatase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
CD4 receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
CD8 receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
ATPase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
enzyme binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
type 5 metabotropic glutamate receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
alpha-tubulin binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
tau protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
tau-protein kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
growth factor receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
disordered domain specific binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
virus receptor activity	Cyclin-dependent kinase 1	Homo sapiens (human)
chromatin binding	Cyclin-dependent kinase 1	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 1	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 1	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 1	Homo sapiens (human)
Hsp70 protein binding	Cyclin-dependent kinase 1	Homo sapiens (human)
histone kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
purine nucleobase binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
protein binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
ATP binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
glucose binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
glycogen phosphorylase activity	Glycogen phosphorylase, liver form	Homo sapiens (human)
AMP binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
vitamin binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
bile acid binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
identical protein binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
linear malto-oligosaccharide phosphorylase activity	Glycogen phosphorylase, liver form	Homo sapiens (human)
SHG alpha-glucan phosphorylase activity	Glycogen phosphorylase, liver form	Homo sapiens (human)
pyridoxal phosphate binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
microtubule binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
immunoglobulin receptor binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
phosphatidylinositol binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein tyrosine kinase activity	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
macrophage colony-stimulating factor receptor activity	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
protein binding	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
ATP binding	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
protein phosphatase binding	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cytokine binding	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
protein homodimerization activity	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
growth factor binding	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 3	Homo sapiens (human)
protein binding	Carbonic anhydrase 3	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 3	Homo sapiens (human)
nickel cation binding	Carbonic anhydrase 3	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Yes	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
enzyme binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
platelet-derived growth factor receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
integrin binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
SH3 domain binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ubiquitin protein ligase binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
gamma-tubulin binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
glycosphingolipid binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphoprotein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphorylation-dependent protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
calcium ion binding	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
protein binding	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
ATP binding	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
signaling receptor activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
G-protein alpha-subunit binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein tyrosine kinase activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor receptor activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
ATP binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor I binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
identical protein binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor substrate binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein-containing complex binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein transporter activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
RNA binding	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
GTP binding	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
ATP hydrolysis activity	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
signal recognition particle binding	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
GTPase activity	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
protein binding	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
ubiquinol-cytochrome-c reductase activity	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
heme binding	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
metal ion binding	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
protein tyrosine kinase activity	Hepatocyte growth factor receptor	Homo sapiens (human)
protein binding	Hepatocyte growth factor receptor	Homo sapiens (human)
ATP binding	Hepatocyte growth factor receptor	Homo sapiens (human)
semaphorin receptor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
protein phosphatase binding	Hepatocyte growth factor receptor	Homo sapiens (human)
identical protein binding	Hepatocyte growth factor receptor	Homo sapiens (human)
molecular function activator activity	Hepatocyte growth factor receptor	Homo sapiens (human)
hepatocyte growth factor receptor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipid binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
monooxygenase activity	Cytochrome P450 3A4	Homo sapiens (human)
steroid binding	Cytochrome P450 3A4	Homo sapiens (human)
iron ion binding	Cytochrome P450 3A4	Homo sapiens (human)
protein binding	Cytochrome P450 3A4	Homo sapiens (human)
steroid hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
retinoic acid 4-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
oxidoreductase activity	Cytochrome P450 3A4	Homo sapiens (human)
oxygen binding	Cytochrome P450 3A4	Homo sapiens (human)
enzyme binding	Cytochrome P450 3A4	Homo sapiens (human)
heme binding	Cytochrome P450 3A4	Homo sapiens (human)
vitamin D3 25-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
caffeine oxidase activity	Cytochrome P450 3A4	Homo sapiens (human)
quinine 3-monooxygenase activity	Cytochrome P450 3A4	Homo sapiens (human)
testosterone 6-beta-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
anandamide 8,9 epoxidase activity	Cytochrome P450 3A4	Homo sapiens (human)
anandamide 11,12 epoxidase activity	Cytochrome P450 3A4	Homo sapiens (human)
anandamide 14,15 epoxidase activity	Cytochrome P450 3A4	Homo sapiens (human)
aromatase activity	Cytochrome P450 3A4	Homo sapiens (human)
vitamin D 24-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
estrogen 16-alpha-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
estrogen 2-hydroxylase activity	Cytochrome P450 3A4	Homo sapiens (human)
1,8-cineole 2-exo-monooxygenase activity	Cytochrome P450 3A4	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
protein binding	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
ATP binding	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
protein phosphatase binding	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
protein tyrosine kinase activity	Macrophage colony-stimulating factor 1 receptor	Mus musculus (house mouse)
protein kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein tyrosine kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet activating factor receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor beta-receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
signaling receptor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
ATP binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
enzyme binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein kinase binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
vascular endothelial growth factor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fgr	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fgr	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
immunoglobulin receptor binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
Fc-gamma receptor I complex binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Fgr	Homo sapiens (human)
magnesium ion binding	Wee1-like protein kinase 2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Wee1-like protein kinase 2	Homo sapiens (human)
ATP binding	Wee1-like protein kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Wee1-like protein kinase 2	Homo sapiens (human)
protein binding	Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)
ATP binding	Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)
protein serine kinase activity	Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)
protein serine/threonine kinase activity	Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
MAP kinase kinase kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protease binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein tyrosine kinase activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
stem cell factor receptor activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
ATP binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cytokine binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
SH2 domain binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein homodimerization activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
metal ion binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
growth factor binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein binding	Glycogen phosphorylase, brain form	Homo sapiens (human)
glycogen phosphorylase activity	Glycogen phosphorylase, brain form	Homo sapiens (human)
linear malto-oligosaccharide phosphorylase activity	Glycogen phosphorylase, brain form	Homo sapiens (human)
SHG alpha-glucan phosphorylase activity	Glycogen phosphorylase, brain form	Homo sapiens (human)
pyridoxal phosphate binding	Glycogen phosphorylase, brain form	Homo sapiens (human)
protein serine/threonine kinase activity	Breakpoint cluster region protein	Homo sapiens (human)
protein tyrosine kinase activity	Breakpoint cluster region protein	Homo sapiens (human)
guanyl-nucleotide exchange factor activity	Breakpoint cluster region protein	Homo sapiens (human)
GTPase activator activity	Breakpoint cluster region protein	Homo sapiens (human)
protein binding	Breakpoint cluster region protein	Homo sapiens (human)
ATP binding	Breakpoint cluster region protein	Homo sapiens (human)
protein serine kinase activity	Breakpoint cluster region protein	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
transcription factor binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
manganese ion binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
ribosomal small subunit binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein tyrosine kinase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
ATP binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
heparin binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
SH2 domain binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
identical protein binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein homodimerization activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
receptor-receptor interaction	Fibroblast growth factor receptor 1	Homo sapiens (human)
magnesium ion binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
chromatin binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
RNA binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	DNA topoisomerase 2-alpha	Homo sapiens (human)
protein kinase C binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
protein binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
ATP binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
ATP-dependent activity, acting on DNA	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA binding, bending	DNA topoisomerase 2-alpha	Homo sapiens (human)
protein homodimerization activity	DNA topoisomerase 2-alpha	Homo sapiens (human)
ubiquitin binding	DNA topoisomerase 2-alpha	Homo sapiens (human)
protein heterodimerization activity	DNA topoisomerase 2-alpha	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 4	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 4	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase regulator activity	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 4	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 4	Homo sapiens (human)
ATP:ADP antiporter activity	ADP/ATP translocase 3	Homo sapiens (human)
protein binding	ADP/ATP translocase 3	Homo sapiens (human)
nucleotide binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
DNA binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
RNA binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
IMP dehydrogenase activity	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
protein binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
metal ion binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
protein kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein kinase C binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signaling receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
insulin receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
integrin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ATP binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phospholipase activator activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
enzyme binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
heme binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nuclear estrogen receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
SH2 domain binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phospholipase binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transmembrane transporter binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cadherin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ephrin receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ATPase binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phosphoprotein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
BMP receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
connexin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
scaffold protein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cAMP-dependent protein kinase inhibitor activity	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cAMP-dependent protein kinase regulator activity	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein domain specific binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
ubiquitin protein ligase binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein kinase A catalytic subunit binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cAMP binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Insulin receptor-related protein	Homo sapiens (human)
protein binding	Insulin receptor-related protein	Homo sapiens (human)
ATP binding	Insulin receptor-related protein	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Insulin receptor-related protein	Homo sapiens (human)
insulin receptor substrate binding	Insulin receptor-related protein	Homo sapiens (human)
insulin receptor activity	Insulin receptor-related protein	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
MAP kinase kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
calcium ion binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
mitogen-activated protein kinase kinase binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
scaffold protein binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
MAP kinase kinase kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
voltage-gated potassium channel activity	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
protein binding	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
potassium channel regulator activity	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
telethonin binding	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
protein-containing complex binding	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
transmembrane transporter binding	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
protein serine/threonine kinase activity	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
phosphorylase kinase activity	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
protein binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
calmodulin binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
ATP binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
enzyme binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
tau-protein kinase activity	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
dihydronicotinamide riboside quinone reductase activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
protein binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
zinc ion binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
electron transfer activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
oxidoreductase activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
oxidoreductase activity, acting on other nitrogenous compounds as donors	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
chloride ion binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
protein homodimerization activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
FAD binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
melatonin binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
resveratrol binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
NAD(P)H dehydrogenase (quinone) activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
protein kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor alpha-receptor activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
ATP binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
vascular endothelial growth factor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein homodimerization activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein-containing complex binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fer	Homo sapiens (human)
epidermal growth factor receptor binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein phosphatase 1 binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
lipid binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein kinase activity	Protein kinase C alpha type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
calcium,diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
integrin binding	Protein kinase C alpha type	Homo sapiens (human)
protein binding	Protein kinase C alpha type	Homo sapiens (human)
ATP binding	Protein kinase C alpha type	Homo sapiens (human)
zinc ion binding	Protein kinase C alpha type	Homo sapiens (human)
enzyme binding	Protein kinase C alpha type	Homo sapiens (human)
histone H3T6 kinase activity	Protein kinase C alpha type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
diacylglycerol binding	Protein kinase C alpha type	Homo sapiens (human)
magnesium ion binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein serine/threonine kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
AMP-activated protein kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein domain specific binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
manganese ion binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
ubiquitin protein ligase binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase A regulatory subunit binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
channel activator activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
placental growth factor receptor activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
protein binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
ATP binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
ATP hydrolysis activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
protein-macromolecule adaptor activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
5'-3' DNA helicase activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
metal ion binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
4 iron, 4 sulfur cluster binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
DNA helicase activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
damaged DNA binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
RNA binding	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
double-stranded RNA binding	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein kinase activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
eukaryotic translation initiation factor 2alpha kinase activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein binding	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
ATP binding	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
kinase activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein phosphatase regulator activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
identical protein binding	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein serine kinase activity	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase II subunit alpha'	Homo sapiens (human)
protein binding	Casein kinase II subunit alpha'	Homo sapiens (human)
ATP binding	Casein kinase II subunit alpha'	Homo sapiens (human)
protein serine kinase activity	Casein kinase II subunit alpha'	Homo sapiens (human)
GTPase activity	Ras-related protein Rab-6A	Homo sapiens (human)
protein binding	Ras-related protein Rab-6A	Homo sapiens (human)
GTP binding	Ras-related protein Rab-6A	Homo sapiens (human)
protein domain specific binding	Ras-related protein Rab-6A	Homo sapiens (human)
myosin V binding	Ras-related protein Rab-6A	Homo sapiens (human)
transcription coactivator activity	Serine/threonine-protein kinase MAK	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase MAK	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MAK	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MAK	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase MAK	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MAK	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MAK	Homo sapiens (human)
RNA binding	Cyclin-dependent kinase 11B	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 11B	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 11B	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 11B	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 11B	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 11B	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 11B	Homo sapiens (human)
fibronectin binding	Ephrin type-A receptor 1	Homo sapiens (human)
protein kinase activity	Ephrin type-A receptor 1	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 1	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 1	Homo sapiens (human)
protein kinase binding	Ephrin type-A receptor 1	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Ephrin type-A receptor 1	Homo sapiens (human)
protein tyrosine kinase activity	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor receptor activity	Fibroblast growth factor receptor 2	Homo sapiens (human)
protein binding	Fibroblast growth factor receptor 2	Homo sapiens (human)
ATP binding	Fibroblast growth factor receptor 2	Homo sapiens (human)
heparin binding	Fibroblast growth factor receptor 2	Homo sapiens (human)
fibroblast growth factor binding	Fibroblast growth factor receptor 2	Homo sapiens (human)
protein homodimerization activity	Fibroblast growth factor receptor 2	Homo sapiens (human)
protein tyrosine kinase activity	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
transmembrane signaling receptor activity	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
protein binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
ATP binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
growth factor binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
protein tyrosine kinase activator activity	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
ubiquitin protein ligase binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
neuregulin binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
identical protein binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
ErbB-3 class receptor binding	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
protein heterodimerization activity	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
neuregulin receptor activity	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
phosphoribosylaminoimidazole carboxylase activity	Multifunctional protein ADE2	Homo sapiens (human)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	Multifunctional protein ADE2	Homo sapiens (human)
protein binding	Multifunctional protein ADE2	Homo sapiens (human)
ATP binding	Multifunctional protein ADE2	Homo sapiens (human)
identical protein binding	Multifunctional protein ADE2	Homo sapiens (human)
5-amino-4-imidazole carboxylate lyase activity	Multifunctional protein ADE2	Homo sapiens (human)
cadherin binding	Multifunctional protein ADE2	Homo sapiens (human)
fibroblast growth factor receptor activity	Fibroblast growth factor receptor 4	Homo sapiens (human)
protein binding	Fibroblast growth factor receptor 4	Homo sapiens (human)
ATP binding	Fibroblast growth factor receptor 4	Homo sapiens (human)
heparin binding	Fibroblast growth factor receptor 4	Homo sapiens (human)
fibroblast growth factor binding	Fibroblast growth factor receptor 4	Homo sapiens (human)
protein tyrosine kinase activity	Fibroblast growth factor receptor 3	Homo sapiens (human)
fibroblast growth factor receptor activity	Fibroblast growth factor receptor 3	Homo sapiens (human)
protein binding	Fibroblast growth factor receptor 3	Homo sapiens (human)
ATP binding	Fibroblast growth factor receptor 3	Homo sapiens (human)
fibroblast growth factor binding	Fibroblast growth factor receptor 3	Homo sapiens (human)
identical protein binding	Fibroblast growth factor receptor 3	Homo sapiens (human)
protein serine/threonine kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
AMP-activated protein kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein kinase A regulatory subunit binding	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
magnesium ion binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein serine/threonine kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
AMP-activated protein kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ubiquitin protein ligase binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein binding	Carbonic anhydrase 4	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 4	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 4	Homo sapiens (human)
ferrochelatase activity	Ferrochelatase, mitochondrial	Homo sapiens (human)
protein binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
ferrous iron binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
iron-responsive element binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
identical protein binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
protein homodimerization activity	Ferrochelatase, mitochondrial	Homo sapiens (human)
2 iron, 2 sulfur cluster binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 6	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 6	Homo sapiens (human)
protein kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
PDZ domain binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
peptide binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
identical protein binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein phosphatase 2A binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase JAK1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase JAK1	Homo sapiens (human)
growth hormone receptor binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
ubiquitin protein ligase binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
CCR5 chemokine receptor binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein kinase activity	Protein kinase C eta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C eta type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C eta type	Homo sapiens (human)
protein binding	Protein kinase C eta type	Homo sapiens (human)
ATP binding	Protein kinase C eta type	Homo sapiens (human)
enzyme binding	Protein kinase C eta type	Homo sapiens (human)
small GTPase binding	Protein kinase C eta type	Homo sapiens (human)
metal ion binding	Protein kinase C eta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C eta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C eta type	Homo sapiens (human)
histone kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
magnesium ion binding	Cyclin-dependent kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 2	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 2	Homo sapiens (human)
protein domain specific binding	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin-dependent protein kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
protein kinase activity	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled receptor kinase activity	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
protein binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
ATP binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
alpha-2A adrenergic receptor binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
Edg-2 lysophosphatidic acid receptor binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
beta-adrenergic receptor kinase activity	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled receptor binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
RNA binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
RNA helicase activity	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
helicase activity	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
protein binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
ATP binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
ATP hydrolysis activity	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
protein domain specific binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cadherin binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
mRNA binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
protein binding	Activin receptor type-2A	Homo sapiens (human)
activin receptor activity	Activin receptor type-2A	Homo sapiens (human)
activin binding	Activin receptor type-2A	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-2A	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Activin receptor type-2A	Homo sapiens (human)
protein binding	Activin receptor type-2A	Homo sapiens (human)
ATP binding	Activin receptor type-2A	Homo sapiens (human)
coreceptor activity	Activin receptor type-2A	Homo sapiens (human)
activin receptor activity	Activin receptor type-2A	Homo sapiens (human)
growth factor binding	Activin receptor type-2A	Homo sapiens (human)
PDZ domain binding	Activin receptor type-2A	Homo sapiens (human)
inhibin binding	Activin receptor type-2A	Homo sapiens (human)
metal ion binding	Activin receptor type-2A	Homo sapiens (human)
BMP receptor activity	Activin receptor type-2A	Homo sapiens (human)
phosphotyrosine residue binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
phosphatase binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
DNA-binding transcription factor binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
protein binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
ATP binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
tau protein binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
tau-protein kinase activity	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
protein serine kinase activity	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
deoxyadenosine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
deoxycytidine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
deoxyguanosine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
ATP binding	Deoxycytidine kinase	Homo sapiens (human)
protein homodimerization activity	Deoxycytidine kinase	Homo sapiens (human)
cytidine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
phosphotyrosine residue binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
DNA binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
phosphatase binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
virus receptor activity	Ephrin type-A receptor 2	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Ephrin type-A receptor 2	Homo sapiens (human)
ephrin receptor activity	Ephrin type-A receptor 2	Homo sapiens (human)
protein binding	Ephrin type-A receptor 2	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 2	Homo sapiens (human)
growth factor binding	Ephrin type-A receptor 2	Homo sapiens (human)
cadherin binding	Ephrin type-A receptor 2	Homo sapiens (human)
molecular function activator activity	Ephrin type-A receptor 2	Homo sapiens (human)
ephrin receptor activity	Ephrin type-A receptor 3	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 3	Homo sapiens (human)
protein binding	Ephrin type-A receptor 3	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 3	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 3	Homo sapiens (human)
ephrin receptor activity	Ephrin type-A receptor 8	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 8	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 8	Homo sapiens (human)
growth factor binding	Ephrin type-A receptor 8	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 8	Homo sapiens (human)
amyloid-beta binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein tyrosine kinase activity	Ephrin type-B receptor 2	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
signaling receptor binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein binding	Ephrin type-B receptor 2	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 2	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
identical protein binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein-containing complex binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein kinase activity	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
protein tyrosine kinase activity	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
protein binding	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
ATP binding	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
receptor signaling protein tyrosine kinase activator activity	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
growth hormone receptor binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
protein binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
ATP binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type 1 angiotensin receptor binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
nucleoside diphosphate kinase activity	UMP-CMP kinase	Homo sapiens (human)
uridine kinase activity	UMP-CMP kinase	Homo sapiens (human)
ATP binding	UMP-CMP kinase	Homo sapiens (human)
UMP kinase activity	UMP-CMP kinase	Homo sapiens (human)
CMP kinase activity	UMP-CMP kinase	Homo sapiens (human)
dCMP kinase activity	UMP-CMP kinase	Homo sapiens (human)
nucleoside monophosphate kinase activity	UMP-CMP kinase	Homo sapiens (human)
cytidylate kinase activity	UMP-CMP kinase	Homo sapiens (human)
RNA binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
serine-type endopeptidase inhibitor activity	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
protein binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
ATP binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
phosphatidylethanolamine binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
enzyme binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
protein kinase binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
magnesium ion binding	Wee1-like protein kinase	Homo sapiens (human)
protein tyrosine kinase activity	Wee1-like protein kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Wee1-like protein kinase	Homo sapiens (human)
protein binding	Wee1-like protein kinase	Homo sapiens (human)
ATP binding	Wee1-like protein kinase	Homo sapiens (human)
heme oxygenase (decyclizing) activity	Heme oxygenase 2	Homo sapiens (human)
protein binding	Heme oxygenase 2	Homo sapiens (human)
metal ion binding	Heme oxygenase 2	Homo sapiens (human)
heme binding	Heme oxygenase 2	Homo sapiens (human)
virus receptor activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
phosphatidylserine binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
protein binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
myosin heavy chain binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 4	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 4	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 4	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 4	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase 4	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase 4	Homo sapiens (human)
protein heterodimerization activity	Mitogen-activated protein kinase 4	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 4	Homo sapiens (human)
methionine adenosyltransferase activity	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
ATP binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
small molecule binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
identical protein binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
metal ion binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
G protein-coupled receptor binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
ATPase activator activity	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
ATP binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
Hsp70 protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
Tat protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
ubiquitin protein ligase binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
metal ion binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
low-density lipoprotein particle receptor binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
unfolded protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein-folding chaperone binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
C3HC4-type RING finger domain binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
calmodulin binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol-3,4,5-trisphosphate binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
enzyme binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein kinase binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nitric-oxide synthase regulator activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase inhibitor activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
identical protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein homodimerization activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol-3,4-bisphosphate binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
14-3-3 protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
potassium channel activator activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
metal ion binding	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
molecular function activator activity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	G protein-coupled receptor kinase 4	Homo sapiens (human)
rhodopsin kinase activity	G protein-coupled receptor kinase 4	Homo sapiens (human)
protein kinase activity	G protein-coupled receptor kinase 4	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
protein binding	Dual specificity protein kinase TTK	Homo sapiens (human)
ATP binding	Dual specificity protein kinase TTK	Homo sapiens (human)
identical protein binding	Dual specificity protein kinase TTK	Homo sapiens (human)
kinetochore binding	Dual specificity protein kinase TTK	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
DNA helicase activity	DNA replication licensing factor MCM4	Homo sapiens (human)
single-stranded DNA binding	DNA replication licensing factor MCM4	Homo sapiens (human)
protein binding	DNA replication licensing factor MCM4	Homo sapiens (human)
ATP binding	DNA replication licensing factor MCM4	Homo sapiens (human)
ATP hydrolysis activity	DNA replication licensing factor MCM4	Homo sapiens (human)
single-stranded DNA helicase activity	DNA replication licensing factor MCM4	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
peroxidase activity	Prostaglandin G/H synthase 2	Homo sapiens (human)
prostaglandin-endoperoxide synthase activity	Prostaglandin G/H synthase 2	Homo sapiens (human)
protein binding	Prostaglandin G/H synthase 2	Homo sapiens (human)
enzyme binding	Prostaglandin G/H synthase 2	Homo sapiens (human)
heme binding	Prostaglandin G/H synthase 2	Homo sapiens (human)
protein homodimerization activity	Prostaglandin G/H synthase 2	Homo sapiens (human)
metal ion binding	Prostaglandin G/H synthase 2	Homo sapiens (human)
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Prostaglandin G/H synthase 2	Homo sapiens (human)
microfilament motor activity	Myosin-10	Homo sapiens (human)
actin filament binding	Myosin-10	Homo sapiens (human)
microfilament motor activity	Myosin-10	Homo sapiens (human)
actin binding	Myosin-10	Homo sapiens (human)
protein binding	Myosin-10	Homo sapiens (human)
calmodulin binding	Myosin-10	Homo sapiens (human)
ATP binding	Myosin-10	Homo sapiens (human)
RNA stem-loop binding	Myosin-10	Homo sapiens (human)
ADP binding	Myosin-10	Homo sapiens (human)
mRNA 5'-UTR binding	Myosin-10	Homo sapiens (human)
actin filament binding	Myosin-10	Homo sapiens (human)
protein binding	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein phosphatase binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein homodimerization activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein tyrosine kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
integrin binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
coreceptor activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
identical protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cadherin binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
Hsp90 protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
MAP-kinase scaffold activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
PDZ domain binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein serine/threonine kinase activator activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
metal ion binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
scaffold protein binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytokine receptor activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
ATP binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
nuclear glucocorticoid receptor binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein-containing complex binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
growth factor binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
protein binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ATP binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
BMP binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
protein homodimerization activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
SMAD binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
metal ion binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
BMP receptor activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
activin receptor activity	Activin receptor type-1B	Homo sapiens (human)
growth factor binding	Activin receptor type-1B	Homo sapiens (human)
activin binding	Activin receptor type-1B	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-1B	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Activin receptor type-1B	Homo sapiens (human)
protein binding	Activin receptor type-1B	Homo sapiens (human)
ATP binding	Activin receptor type-1B	Homo sapiens (human)
activin receptor activity, type I	Activin receptor type-1B	Homo sapiens (human)
activin receptor activity	Activin receptor type-1B	Homo sapiens (human)
ubiquitin protein ligase binding	Activin receptor type-1B	Homo sapiens (human)
inhibin binding	Activin receptor type-1B	Homo sapiens (human)
SMAD binding	Activin receptor type-1B	Homo sapiens (human)
metal ion binding	Activin receptor type-1B	Homo sapiens (human)
I-SMAD binding	Activin receptor type-1B	Homo sapiens (human)
transforming growth factor beta receptor activity	TGF-beta receptor type-1	Homo sapiens (human)
growth factor binding	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-1	Homo sapiens (human)
protein kinase activity	TGF-beta receptor type-1	Homo sapiens (human)
protein serine/threonine kinase activity	TGF-beta receptor type-1	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor activity	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	TGF-beta receptor type-1	Homo sapiens (human)
type II transforming growth factor beta receptor binding	TGF-beta receptor type-1	Homo sapiens (human)
protein binding	TGF-beta receptor type-1	Homo sapiens (human)
ATP binding	TGF-beta receptor type-1	Homo sapiens (human)
ubiquitin protein ligase binding	TGF-beta receptor type-1	Homo sapiens (human)
SMAD binding	TGF-beta receptor type-1	Homo sapiens (human)
metal ion binding	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-1	Homo sapiens (human)
I-SMAD binding	TGF-beta receptor type-1	Homo sapiens (human)
activin receptor activity, type I	TGF-beta receptor type-1	Homo sapiens (human)
activin binding	TGF-beta receptor type-1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
transforming growth factor beta receptor activity	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
activin receptor activity, type I	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
SMAD binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
activin binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
transforming growth factor beta binding	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
BMP receptor activity	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-2	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor activity	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor activity, type II	TGF-beta receptor type-2	Homo sapiens (human)
protein binding	TGF-beta receptor type-2	Homo sapiens (human)
ATP binding	TGF-beta receptor type-2	Homo sapiens (human)
glycosaminoglycan binding	TGF-beta receptor type-2	Homo sapiens (human)
kinase activator activity	TGF-beta receptor type-2	Homo sapiens (human)
type I transforming growth factor beta receptor binding	TGF-beta receptor type-2	Homo sapiens (human)
SMAD binding	TGF-beta receptor type-2	Homo sapiens (human)
metal ion binding	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-2	Homo sapiens (human)
molecular adaptor activity	TGF-beta receptor type-2	Homo sapiens (human)
activin receptor activity	TGF-beta receptor type-2	Homo sapiens (human)
activin binding	TGF-beta receptor type-2	Homo sapiens (human)
protein serine/threonine kinase activity	TGF-beta receptor type-2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein kinase A catalytic subunit binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
proline-rich region binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein tyrosine kinase binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase CSK	Homo sapiens (human)
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	Glycine--tRNA ligase	Homo sapiens (human)
glycine-tRNA ligase activity	Glycine--tRNA ligase	Homo sapiens (human)
protein binding	Glycine--tRNA ligase	Homo sapiens (human)
ATP binding	Glycine--tRNA ligase	Homo sapiens (human)
transferase activity	Glycine--tRNA ligase	Homo sapiens (human)
identical protein binding	Glycine--tRNA ligase	Homo sapiens (human)
protein dimerization activity	Glycine--tRNA ligase	Homo sapiens (human)
protein kinase activity	Protein kinase C iota type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C iota type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C iota type	Homo sapiens (human)
protein binding	Protein kinase C iota type	Homo sapiens (human)
ATP binding	Protein kinase C iota type	Homo sapiens (human)
phospholipid binding	Protein kinase C iota type	Homo sapiens (human)
metal ion binding	Protein kinase C iota type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C iota type	Homo sapiens (human)
RNA binding	Exosome RNA helicase MTR4	Homo sapiens (human)
RNA helicase activity	Exosome RNA helicase MTR4	Homo sapiens (human)
protein binding	Exosome RNA helicase MTR4	Homo sapiens (human)
ATP binding	Exosome RNA helicase MTR4	Homo sapiens (human)
ATP hydrolysis activity	Exosome RNA helicase MTR4	Homo sapiens (human)
protein serine/threonine kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
protein binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
1-phosphatidylinositol-3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
protein kinase activator activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
insulin receptor substrate binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
protein serine kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
protein binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
1-phosphatidylinositol-3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
insulin receptor substrate binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
protein serine kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
RNA polymerase III type 1 promoter sequence-specific DNA binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
RNA polymerase III type 2 promoter sequence-specific DNA binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
RNA polymerase III type 3 promoter sequence-specific DNA binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
TFIIIC-class transcription factor complex binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
ribosome binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
phosphoprotein binding	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
protein tyrosine kinase activity	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
protein binding	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
ATP binding	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Tec	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
phospholipid binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
protein binding	Tyrosine-protein kinase TXK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase TXK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase TXK	Homo sapiens (human)
magnesium ion binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
actin monomer binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
manganese ion binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
actin filament binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase FRK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase FRK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase FRK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase FRK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase FRK	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 7	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 7	Homo sapiens (human)
protein binding	G protein-coupled receptor kinase 6	Homo sapiens (human)
ATP binding	G protein-coupled receptor kinase 6	Homo sapiens (human)
beta-adrenergic receptor kinase activity	G protein-coupled receptor kinase 6	Homo sapiens (human)
G protein-coupled receptor kinase activity	G protein-coupled receptor kinase 6	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein serine/threonine kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
integrin binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
interleukin-15 receptor binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
phosphatase binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
Toll-like receptor binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein binding	26S proteasome regulatory subunit 6B	Homo sapiens (human)
ATP binding	26S proteasome regulatory subunit 6B	Homo sapiens (human)
ATP hydrolysis activity	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome-activating activity	26S proteasome regulatory subunit 6B	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
JUN kinase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
enzyme binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein phosphatase binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
histone deacetylase regulator activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
histone deacetylase binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein serine/threonine kinase binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
JUN kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 9	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
JUN kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
molecular adaptor activity	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein kinase binding	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
ATP binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
1-phosphatidylinositol-5-phosphate 4-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
protein homodimerization activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform alpha	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform alpha	Homo sapiens (human)
protein binding	Casein kinase I isoform alpha	Homo sapiens (human)
ATP binding	Casein kinase I isoform alpha	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform alpha	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein binding	Casein kinase I isoform delta	Homo sapiens (human)
ATP binding	Casein kinase I isoform delta	Homo sapiens (human)
cadherin binding	Casein kinase I isoform delta	Homo sapiens (human)
tau-protein kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
protein serine/threonine kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
protein binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
1-phosphatidylinositol-3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
identical protein binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
ephrin receptor binding	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
protein serine kinase activity	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
protein kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
ATP binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein serine kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
calmodulin binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
calmodulin-dependent protein kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
mitogen-activated protein kinase binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 8	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 8	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 8	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 8	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 8	Homo sapiens (human)
ubiquitin protein ligase activity	Cyclin-dependent kinase 8	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 8	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 8	Homo sapiens (human)
RNA binding	Elongation factor Tu, mitochondrial	Homo sapiens (human)
translation elongation factor activity	Elongation factor Tu, mitochondrial	Homo sapiens (human)
GTPase activity	Elongation factor Tu, mitochondrial	Homo sapiens (human)
protein binding	Elongation factor Tu, mitochondrial	Homo sapiens (human)
GTP binding	Elongation factor Tu, mitochondrial	Homo sapiens (human)
tRNA binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cysteine-tRNA ligase activity	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
protein binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
ATP binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
identical protein binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
metal ion binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
RNA binding	Casein kinase I isoform epsilon	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform epsilon	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform epsilon	Homo sapiens (human)
protein binding	Casein kinase I isoform epsilon	Homo sapiens (human)
ATP binding	Casein kinase I isoform epsilon	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform epsilon	Homo sapiens (human)
acyl-CoA dehydrogenase activity	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
long-chain fatty acyl-CoA dehydrogenase activity	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
protein binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
very-long-chain fatty acyl-CoA dehydrogenase activity	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
identical protein binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
flavin adenine dinucleotide binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
fatty-acyl-CoA binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK1	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK2	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK2	Homo sapiens (human)
identical protein binding	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
RNA binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
identical protein binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine/threonine kinase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
signaling receptor binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
ATP binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein kinase A catalytic subunit binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
tau protein binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
tau-protein kinase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein serine kinase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protease binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
p53 binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein serine/threonine kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
ATP binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
beta-catenin binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
ubiquitin protein ligase binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase A catalytic subunit binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
dynactin binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
tau protein binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
tau-protein kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
NF-kappaB binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein serine kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 7	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 7	Homo sapiens (human)
ATP-dependent activity, acting on DNA	Cyclin-dependent kinase 7	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription coactivator binding	Cyclin-dependent kinase 9	Homo sapiens (human)
DNA binding	Cyclin-dependent kinase 9	Homo sapiens (human)
chromatin binding	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation factor activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 9	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 9	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein kinase binding	Cyclin-dependent kinase 9	Homo sapiens (human)
7SK snRNA binding	Cyclin-dependent kinase 9	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
GTPase activity	Ras-related protein Rab-27A	Homo sapiens (human)
G protein activity	Ras-related protein Rab-27A	Homo sapiens (human)
protein binding	Ras-related protein Rab-27A	Homo sapiens (human)
GTP binding	Ras-related protein Rab-27A	Homo sapiens (human)
GDP binding	Ras-related protein Rab-27A	Homo sapiens (human)
protein domain specific binding	Ras-related protein Rab-27A	Homo sapiens (human)
myosin V binding	Ras-related protein Rab-27A	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Blk	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Blk	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
protein kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
ATP binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein kinase binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
heat shock protein binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
identical protein binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein homodimerization activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein heterodimerization activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein serine kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
voltage-gated potassium channel activity	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
voltage-gated potassium channel activity	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
protein binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
calmodulin binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
phosphatidylinositol-4,5-bisphosphate binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
protein phosphatase 1 binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
outward rectifier potassium channel activity	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
protein kinase A catalytic subunit binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
protein kinase A regulatory subunit binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
transmembrane transporter binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
scaffold protein binding	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein kinase binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein tyrosine kinase activity	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
protein binding	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
ATP binding	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
metal ion binding	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein phosphatase binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
manganese ion binding	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase JAK3	Homo sapiens (human)
protein binding	Tyrosine-protein kinase JAK3	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase JAK3	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase JAK3	Homo sapiens (human)
growth hormone receptor binding	Tyrosine-protein kinase JAK3	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase JAK3	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein kinase binding	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
microtubule binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
anaphase-promoting complex binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein kinase activity	Death-associated protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Death-associated protein kinase 1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Death-associated protein kinase 1	Homo sapiens (human)
protein binding	Death-associated protein kinase 1	Homo sapiens (human)
calmodulin binding	Death-associated protein kinase 1	Homo sapiens (human)
ATP binding	Death-associated protein kinase 1	Homo sapiens (human)
GTP binding	Death-associated protein kinase 1	Homo sapiens (human)
syntaxin-1 binding	Death-associated protein kinase 1	Homo sapiens (human)
identical protein binding	Death-associated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Death-associated protein kinase 1	Homo sapiens (human)
protein kinase activity	LIM domain kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	LIM domain kinase 1	Homo sapiens (human)
protein binding	LIM domain kinase 1	Homo sapiens (human)
ATP binding	LIM domain kinase 1	Homo sapiens (human)
heat shock protein binding	LIM domain kinase 1	Homo sapiens (human)
metal ion binding	LIM domain kinase 1	Homo sapiens (human)
protein serine kinase activity	LIM domain kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	LIM domain kinase 2	Homo sapiens (human)
protein binding	LIM domain kinase 2	Homo sapiens (human)
ATP binding	LIM domain kinase 2	Homo sapiens (human)
metal ion binding	LIM domain kinase 2	Homo sapiens (human)
protein serine kinase activity	LIM domain kinase 2	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase 12	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 12	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 12	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 12	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 12	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 12	Homo sapiens (human)
JUN kinase activity	Mitogen-activated protein kinase 10	Homo sapiens (human)
MAP kinase kinase activity	Mitogen-activated protein kinase 10	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 10	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 10	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 10	Homo sapiens (human)
tRNA binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
RNA binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
tyrosine-tRNA ligase activity	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
interleukin-8 receptor binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
protein binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
ATP binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
small molecule binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
protein kinase activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cAMP-dependent protein kinase activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cAMP-dependent protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
AMP binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein kinase binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
ADP binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
chromatin binding	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein serine/threonine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
AMP-activated protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
metal ion binding	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
protein serine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
histone H2BS36 kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
ephrin receptor activity	Ephrin type-B receptor 3	Homo sapiens (human)
protein binding	Ephrin type-B receptor 3	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 3	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-B receptor 3	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 3	Homo sapiens (human)
ephrin receptor activity	Ephrin type-A receptor 5	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 5	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 5	Homo sapiens (human)
protein binding	Ephrin type-A receptor 5	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 5	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Ephrin type-B receptor 4	Homo sapiens (human)
ephrin receptor activity	Ephrin type-B receptor 4	Homo sapiens (human)
protein binding	Ephrin type-B receptor 4	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 4	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 1	Homo sapiens (human)
protein binding	Ephrin type-B receptor 1	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 1	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-B receptor 1	Homo sapiens (human)
protein-containing complex binding	Ephrin type-B receptor 1	Homo sapiens (human)
amyloid-beta binding	Ephrin type-A receptor 4	Homo sapiens (human)
protein kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
protein tyrosine kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 4	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 4	Homo sapiens (human)
protein binding	Ephrin type-A receptor 4	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 4	Homo sapiens (human)
kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
PH domain binding	Ephrin type-A receptor 4	Homo sapiens (human)
identical protein binding	Ephrin type-A receptor 4	Homo sapiens (human)
ephrin receptor binding	Ephrin type-A receptor 4	Homo sapiens (human)
DH domain binding	Ephrin type-A receptor 4	Homo sapiens (human)
protein tyrosine kinase binding	Ephrin type-A receptor 4	Homo sapiens (human)
adenylate kinase activity	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
protein binding	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
ATP binding	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
RNA binding	Adenosine kinase	Homo sapiens (human)
deoxyadenosine kinase activity	Adenosine kinase	Homo sapiens (human)
ATP binding	Adenosine kinase	Homo sapiens (human)
metal ion binding	Adenosine kinase	Homo sapiens (human)
adenosine kinase activity	Adenosine kinase	Homo sapiens (human)
protein binding	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
ATP binding	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
protein serine kinase activity	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
cAMP response element binding protein binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
histone deacetylase binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
14-3-3 protein binding	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
protein serine/threonine kinase activity	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
protein binding	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
ATP binding	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine kinase activity	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
G protein activity	Ras-related protein Rab-10	Homo sapiens (human)
protein binding	Ras-related protein Rab-10	Homo sapiens (human)
GTP binding	Ras-related protein Rab-10	Homo sapiens (human)
GDP binding	Ras-related protein Rab-10	Homo sapiens (human)
myosin V binding	Ras-related protein Rab-10	Homo sapiens (human)
cadherin binding involved in cell-cell adhesion	Ras-related protein Rab-10	Homo sapiens (human)
actin filament binding	Actin-related protein 3	Homo sapiens (human)
structural constituent of cytoskeleton	Actin-related protein 3	Homo sapiens (human)
protein binding	Actin-related protein 3	Homo sapiens (human)
ATP binding	Actin-related protein 3	Homo sapiens (human)
actin filament binding	Actin-related protein 2	Homo sapiens (human)
structural constituent of cytoskeleton	Actin-related protein 2	Homo sapiens (human)
protein binding	Actin-related protein 2	Homo sapiens (human)
ATP binding	Actin-related protein 2	Homo sapiens (human)
nuclear export signal receptor activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
pre-miRNA binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
magnesium ion binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
chromatin binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
RNA binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTPase activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
G protein activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTP binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GDP binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein domain specific binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
cadherin binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
dynein intermediate chain binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein heterodimerization activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
importin-alpha family protein binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTPase activity	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
G protein activity	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
protein binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
GTP binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
enzyme binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
protein kinase binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
thioesterase binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
protein-containing complex binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
Rho GDP-dissociation inhibitor binding	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase II subunit alpha	Homo sapiens (human)
protein binding	Casein kinase II subunit alpha	Homo sapiens (human)
ATP binding	Casein kinase II subunit alpha	Homo sapiens (human)
kinase activity	Casein kinase II subunit alpha	Homo sapiens (human)
identical protein binding	Casein kinase II subunit alpha	Homo sapiens (human)
Hsp90 protein binding	Casein kinase II subunit alpha	Homo sapiens (human)
protein serine kinase activity	Casein kinase II subunit alpha	Homo sapiens (human)
protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
ATP binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
GTP binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
protein homodimerization activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
1-phosphatidylinositol-5-phosphate 4-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
magnesium ion binding	SRSF protein kinase 2	Homo sapiens (human)
RNA binding	SRSF protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	SRSF protein kinase 2	Homo sapiens (human)
protein binding	SRSF protein kinase 2	Homo sapiens (human)
ATP binding	SRSF protein kinase 2	Homo sapiens (human)
14-3-3 protein binding	SRSF protein kinase 2	Homo sapiens (human)
protein serine kinase activity	SRSF protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform gamma-2	Homo sapiens (human)
protein binding	Casein kinase I isoform gamma-2	Homo sapiens (human)
ATP binding	Casein kinase I isoform gamma-2	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform gamma-2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
MAP kinase kinase activity	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
molecular function activator activity	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 3	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 3	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 3	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 3	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 3	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase-like 1	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase-like 1	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase-like 1	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase-like 1	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 6	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 6	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 6	Homo sapiens (human)
FBXO family protein binding	Cyclin-dependent kinase 6	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 6	Homo sapiens (human)
microtubule binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
p53 binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
ErbB-2 class receptor binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
ATP binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
acetylcholine receptor activator activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
ErbB-3 class receptor binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
tau protein binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
tau-protein kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
Hsp90 protein binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 16	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 16	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 16	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 16	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 16	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 17	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 17	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 17	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 17	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 17	Homo sapiens (human)
high voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
protein binding	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
ankyrin binding	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
metal ion binding	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
alpha-actinin binding	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
voltage-gated calcium channel activity involved in cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
voltage-gated calcium channel activity involved SA node cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
6-phosphofructokinase activity	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
protein binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
protein-containing complex binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
cadherin binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
metal ion binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
ATP binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
monosaccharide binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
AMP binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
identical protein binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
fructose-6-phosphate binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
actin monomer binding	Protein kinase C epsilon type	Homo sapiens (human)
protein kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
protein binding	Protein kinase C epsilon type	Homo sapiens (human)
ATP binding	Protein kinase C epsilon type	Homo sapiens (human)
enzyme activator activity	Protein kinase C epsilon type	Homo sapiens (human)
enzyme binding	Protein kinase C epsilon type	Homo sapiens (human)
signaling receptor activator activity	Protein kinase C epsilon type	Homo sapiens (human)
ethanol binding	Protein kinase C epsilon type	Homo sapiens (human)
metal ion binding	Protein kinase C epsilon type	Homo sapiens (human)
14-3-3 protein binding	Protein kinase C epsilon type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
MAP-kinase scaffold activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein kinase activator activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activator activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
scaffold protein binding	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
protein binding	Angiopoietin-1 receptor	Homo sapiens (human)
ATP binding	Angiopoietin-1 receptor	Homo sapiens (human)
growth factor binding	Angiopoietin-1 receptor	Homo sapiens (human)
signaling receptor activity	Angiopoietin-1 receptor	Homo sapiens (human)
identical protein binding	Angiopoietin-1 receptor	Homo sapiens (human)
transcription corepressor activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
bHLH transcription factor binding	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
DNA binding	DNA topoisomerase 2-beta	Homo sapiens (human)
chromatin binding	DNA topoisomerase 2-beta	Homo sapiens (human)
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	DNA topoisomerase 2-beta	Homo sapiens (human)
protein binding	DNA topoisomerase 2-beta	Homo sapiens (human)
ATP binding	DNA topoisomerase 2-beta	Homo sapiens (human)
ribonucleoprotein complex binding	DNA topoisomerase 2-beta	Homo sapiens (human)
metal ion binding	DNA topoisomerase 2-beta	Homo sapiens (human)
protein kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C theta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein binding	Protein kinase C theta type	Homo sapiens (human)
ATP binding	Protein kinase C theta type	Homo sapiens (human)
metal ion binding	Protein kinase C theta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C theta type	Homo sapiens (human)
activin receptor activity, type I	Activin receptor type-1	Homo sapiens (human)
protein kinase activity	Activin receptor type-1	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-1	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Activin receptor type-1	Homo sapiens (human)
protein binding	Activin receptor type-1	Homo sapiens (human)
ATP binding	Activin receptor type-1	Homo sapiens (human)
peptide hormone binding	Activin receptor type-1	Homo sapiens (human)
protein homodimerization activity	Activin receptor type-1	Homo sapiens (human)
cadherin binding	Activin receptor type-1	Homo sapiens (human)
SMAD binding	Activin receptor type-1	Homo sapiens (human)
metal ion binding	Activin receptor type-1	Homo sapiens (human)
activin binding	Activin receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	Activin receptor type-1	Homo sapiens (human)
BMP receptor activity	Activin receptor type-1	Homo sapiens (human)
protein tyrosine kinase binding	Activin receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Activin receptor type-1	Homo sapiens (human)
macrophage colony-stimulating factor receptor activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
protein binding	Macrophage-stimulating protein receptor	Homo sapiens (human)
ATP binding	Macrophage-stimulating protein receptor	Homo sapiens (human)
enzyme binding	Macrophage-stimulating protein receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
actin binding	Focal adhesion kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Focal adhesion kinase 1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Focal adhesion kinase 1	Homo sapiens (human)
protein tyrosine phosphatase activity	Focal adhesion kinase 1	Homo sapiens (human)
integrin binding	Focal adhesion kinase 1	Homo sapiens (human)
protein binding	Focal adhesion kinase 1	Homo sapiens (human)
ATP binding	Focal adhesion kinase 1	Homo sapiens (human)
JUN kinase binding	Focal adhesion kinase 1	Homo sapiens (human)
protein kinase binding	Focal adhesion kinase 1	Homo sapiens (human)
protein phosphatase binding	Focal adhesion kinase 1	Homo sapiens (human)
SH2 domain binding	Focal adhesion kinase 1	Homo sapiens (human)
molecular function activator activity	Focal adhesion kinase 1	Homo sapiens (human)
protein kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein binding	Protein kinase C zeta type	Homo sapiens (human)
ATP binding	Protein kinase C zeta type	Homo sapiens (human)
potassium channel regulator activity	Protein kinase C zeta type	Homo sapiens (human)
protein kinase binding	Protein kinase C zeta type	Homo sapiens (human)
phospholipase binding	Protein kinase C zeta type	Homo sapiens (human)
insulin receptor substrate binding	Protein kinase C zeta type	Homo sapiens (human)
protein-containing complex binding	Protein kinase C zeta type	Homo sapiens (human)
metal ion binding	Protein kinase C zeta type	Homo sapiens (human)
14-3-3 protein binding	Protein kinase C zeta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein binding	Protein kinase C delta type	Homo sapiens (human)
ATP binding	Protein kinase C delta type	Homo sapiens (human)
enzyme activator activity	Protein kinase C delta type	Homo sapiens (human)
enzyme binding	Protein kinase C delta type	Homo sapiens (human)
protein kinase binding	Protein kinase C delta type	Homo sapiens (human)
insulin receptor substrate binding	Protein kinase C delta type	Homo sapiens (human)
metal ion binding	Protein kinase C delta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
phosphatidylinositol-3,4,5-trisphosphate binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
virus receptor activity	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
protein binding	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 18	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 18	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 18	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 18	Homo sapiens (human)
protein serine/threonine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
GTPase inhibitor activity	Activated CDC42 kinase 1	Homo sapiens (human)
epidermal growth factor receptor binding	Activated CDC42 kinase 1	Homo sapiens (human)
protein binding	Activated CDC42 kinase 1	Homo sapiens (human)
ATP binding	Activated CDC42 kinase 1	Homo sapiens (human)
ubiquitin protein ligase binding	Activated CDC42 kinase 1	Homo sapiens (human)
identical protein binding	Activated CDC42 kinase 1	Homo sapiens (human)
metal ion binding	Activated CDC42 kinase 1	Homo sapiens (human)
WW domain binding	Activated CDC42 kinase 1	Homo sapiens (human)
protein serine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
protein binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
collagen binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
ATP binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
protein tyrosine kinase collagen receptor activity	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
metal ion binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
protein serine/threonine kinase activity	Myotonin-protein kinase	Homo sapiens (human)
protein binding	Myotonin-protein kinase	Homo sapiens (human)
ATP binding	Myotonin-protein kinase	Homo sapiens (human)
myosin phosphatase regulator activity	Myotonin-protein kinase	Homo sapiens (human)
metal ion binding	Myotonin-protein kinase	Homo sapiens (human)
protein serine kinase activity	Myotonin-protein kinase	Homo sapiens (human)
transcription cis-regulatory region binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
inward rectifier potassium channel activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
ubiquitin protein ligase binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
identical protein binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein homodimerization activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
C3HC4-type RING finger domain binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
scaffold protein binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
mitogen-activated protein kinase kinase kinase binding	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein serine/threonine kinase activator activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Mer	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Mer	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Tyrosine-protein kinase Mer	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
chromatin binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein serine/threonine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
AMP-activated protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cAMP-dependent protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
metal ion binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
tau protein binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
tau-protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein serine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
histone H2BS36 kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
collagen binding	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
gamma-tubulin binding	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
metal ion binding	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
enzyme inhibitor activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 7	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 7	Homo sapiens (human)
mitogen-activated protein kinase binding	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein tyrosine kinase activator activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
zinc ion binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein kinase activity	cGMP-dependent protein kinase 2	Homo sapiens (human)
cGMP-dependent protein kinase activity	cGMP-dependent protein kinase 2	Homo sapiens (human)
ATP binding	cGMP-dependent protein kinase 2	Homo sapiens (human)
cGMP binding	cGMP-dependent protein kinase 2	Homo sapiens (human)
identical protein binding	cGMP-dependent protein kinase 2	Homo sapiens (human)
mitogen-activated protein kinase binding	cGMP-dependent protein kinase 2	Homo sapiens (human)
protein serine kinase activity	cGMP-dependent protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Integrin-linked protein kinase	Homo sapiens (human)
protein binding	Integrin-linked protein kinase	Homo sapiens (human)
ATP binding	Integrin-linked protein kinase	Homo sapiens (human)
protein kinase binding	Integrin-linked protein kinase	Homo sapiens (human)
protein serine kinase activity	Integrin-linked protein kinase	Homo sapiens (human)
protein kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein binding	Rho-associated protein kinase 1	Homo sapiens (human)
ATP binding	Rho-associated protein kinase 1	Homo sapiens (human)
small GTPase binding	Rho-associated protein kinase 1	Homo sapiens (human)
metal ion binding	Rho-associated protein kinase 1	Homo sapiens (human)
tau protein binding	Rho-associated protein kinase 1	Homo sapiens (human)
tau-protein kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
Rho-dependent protein serine/threonine kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
protein binding	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
ATP binding	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
RNA binding	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
protein kinase activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
death receptor binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
ATP binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
ubiquitin protein ligase binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
signaling adaptor activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
identical protein binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein homodimerization activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein-containing complex binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
death domain binding	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
JUN kinase kinase kinase activity	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
actin binding	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
identical protein binding	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
protein homodimerization activity	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
calcium-dependent protein serine/threonine phosphatase activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
identical protein binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein homodimerization activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
sodium channel inhibitor activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
titin binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
identical protein binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein homodimerization activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
transmembrane transporter binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
ATP binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
identical protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
tau protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
tau-protein kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein serine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
histone H3T45 kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
transcription coactivator activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
protein binding	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
calmodulin binding	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
high voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
small molecule binding	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
metal ion binding	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
molecular function activator activity	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
activin receptor activity, type II	Activin receptor type-2B	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-2B	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Activin receptor type-2B	Homo sapiens (human)
protein binding	Activin receptor type-2B	Homo sapiens (human)
ATP binding	Activin receptor type-2B	Homo sapiens (human)
activin receptor activity, type II	Activin receptor type-2B	Homo sapiens (human)
kinase activator activity	Activin receptor type-2B	Homo sapiens (human)
growth factor binding	Activin receptor type-2B	Homo sapiens (human)
metal ion binding	Activin receptor type-2B	Homo sapiens (human)
activin binding	Activin receptor type-2B	Homo sapiens (human)
activin receptor activity	Activin receptor type-2B	Homo sapiens (human)
protein binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
ATP binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
activin receptor activity, type II	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
growth factor binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
BMP binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cadherin binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
metal ion binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
BMP receptor activity	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein tyrosine kinase binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor activity	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein tyrosine kinase activity	Protein-tyrosine kinase 6	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein-tyrosine kinase 6	Homo sapiens (human)
protein binding	Protein-tyrosine kinase 6	Homo sapiens (human)
ATP binding	Protein-tyrosine kinase 6	Homo sapiens (human)
identical protein binding	Protein-tyrosine kinase 6	Homo sapiens (human)
signaling receptor binding	Protein-tyrosine kinase 6	Homo sapiens (human)
high voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
voltage-gated calcium channel activity involved in cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
protein binding	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
calmodulin binding	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
high voltage-gated calcium channel activity	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
metal ion binding	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
alpha-actinin binding	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
voltage-gated calcium channel activity involved in cardiac muscle cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
voltage-gated calcium channel activity involved in AV node cell action potential	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
protein kinase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
cGMP-dependent protein kinase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
calcium channel regulator activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
protein binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
ATP binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
cGMP binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
identical protein binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
mitogen-activated protein kinase p38 binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
protein serine kinase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
RNA binding	Cyclin-dependent kinase 13	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 13	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 13	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
protein kinase binding	Cyclin-dependent kinase 13	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 13	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
K63-linked polyubiquitin modification-dependent protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
protein serine/threonine kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
ATP binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
IkappaB kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
protein phosphatase binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
ubiquitin protein ligase binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
K48-linked polyubiquitin modification-dependent protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
identical protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein tyrosine kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
ATP binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
ubiquitin protein ligase binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
glutamate receptor binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
3-phosphoinositide-dependent protein kinase binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein-containing complex binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
neurotransmitter receptor regulator activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
voltage-gated sodium channel activity	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
protein binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
calmodulin binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
fibroblast growth factor binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
enzyme binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
protein kinase binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
protein domain specific binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
ankyrin binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
ubiquitin protein ligase binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
transmembrane transporter binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
nitric-oxide synthase binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
voltage-gated sodium channel activity involved in AV node cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
voltage-gated sodium channel activity involved in bundle of His cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
voltage-gated sodium channel activity involved in Purkinje myocyte action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
voltage-gated sodium channel activity involved in SA node cell action potential	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
scaffold protein binding	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
protein serine/threonine kinase activity	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
calcium ion binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
ATP binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
lipid binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein serine kinase activity	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
chromatin binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
RNA binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
protein binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
ATP binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
ATP hydrolysis activity	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mediator complex binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
protein heterodimerization activity	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
DNA binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleosomal DNA binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
transcription coregulator binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
transcription corepressor activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
helicase activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
protein binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
ATP binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
zinc ion binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
ATP hydrolysis activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
histone deacetylase binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
ATP-dependent chromatin remodeler activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
chromatin binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
DNA binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
histone binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein kinase C binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
heat shock protein binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 38	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 38	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 38	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 38	Homo sapiens (human)
mitogen-activated protein kinase kinase kinase binding	Serine/threonine-protein kinase 38	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase 38	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 38	Homo sapiens (human)
histone reader activity	Serine/threonine-protein kinase 38	Homo sapiens (human)
UFM1-modified protein reader activity	Serine/threonine-protein kinase 38	Homo sapiens (human)
transcription cis-regulatory region binding	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
protein tyrosine kinase activity	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
epidermal growth factor receptor activity	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
epidermal growth factor receptor binding	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
protein binding	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
ATP binding	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
neuregulin receptor activity	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
protein homodimerization activity	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
GABA receptor binding	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
protein tyrosine kinase activity	Ephrin type-A receptor 7	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 7	Homo sapiens (human)
protein binding	Ephrin type-A receptor 7	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 7	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-A receptor 7	Homo sapiens (human)
growth factor binding	Ephrin type-A receptor 7	Homo sapiens (human)
chemorepellent activity	Ephrin type-A receptor 7	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 7	Homo sapiens (human)
delta24(24-1) sterol reductase activity	Delta(24)-sterol reductase	Homo sapiens (human)
protein binding	Delta(24)-sterol reductase	Homo sapiens (human)
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	Delta(24)-sterol reductase	Homo sapiens (human)
enzyme binding	Delta(24)-sterol reductase	Homo sapiens (human)
peptide antigen binding	Delta(24)-sterol reductase	Homo sapiens (human)
delta24-sterol reductase activity	Delta(24)-sterol reductase	Homo sapiens (human)
FAD binding	Delta(24)-sterol reductase	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein kinase activity	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein binding	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
ATP binding	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein kinase binding	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
metal ion binding	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
actin binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
myosin light chain kinase activity	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
protein binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
calmodulin binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
ATP binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
metal ion binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 11	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 11	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 11	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 11	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 11	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
p53 binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
LRR domain binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein kinase activator activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein kinase activity	Rhodopsin kinase GRK1	Homo sapiens (human)
ATP binding	Rhodopsin kinase GRK1	Homo sapiens (human)
rhodopsin kinase activity	Rhodopsin kinase GRK1	Homo sapiens (human)
p53 binding	NT-3 growth factor receptor	Homo sapiens (human)
neurotrophin receptor activity	NT-3 growth factor receptor	Homo sapiens (human)
protein binding	NT-3 growth factor receptor	Homo sapiens (human)
ATP binding	NT-3 growth factor receptor	Homo sapiens (human)
neurotrophin binding	NT-3 growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	NT-3 growth factor receptor	Homo sapiens (human)
chromatin binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein kinase C binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
nuclear receptor coactivator activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
histone H3T11 kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
histone binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
histone deacetylase binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
nuclear androgen receptor binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
RNA binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
histone deacetylase binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
RNA polymerase binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
MAP kinase kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
enzyme binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
protein phosphatase binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
mitogen-activated protein kinase p38 binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
NFAT protein binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
small GTPase binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
mitogen-activated protein kinase kinase binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
mitogen-activated protein kinase kinase kinase binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protease binding	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
protein binding	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
ATP binding	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
protein homodimerization activity	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
neurotrophin binding	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
brain-derived neurotrophic factor binding	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
brain-derived neurotrophic factor receptor activity	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 6	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 6	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 6	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 6	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase 6	Homo sapiens (human)
protein heterodimerization activity	Mitogen-activated protein kinase 6	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 6	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 9	Homo sapiens (human)
protein binding	Carbonic anhydrase 9	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 9	Homo sapiens (human)
molecular function activator activity	Carbonic anhydrase 9	Homo sapiens (human)
phosphorylase kinase activity	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
calmodulin binding	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
ATP binding	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
enzyme binding	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
tau-protein kinase activity	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
protein serine kinase activity	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein binding	Discoidin domain-containing receptor 2	Homo sapiens (human)
collagen binding	Discoidin domain-containing receptor 2	Homo sapiens (human)
ATP binding	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein tyrosine kinase collagen receptor activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein serine/threonine kinase activity	AP2-associated protein kinase 1	Homo sapiens (human)
Notch binding	AP2-associated protein kinase 1	Homo sapiens (human)
protein binding	AP2-associated protein kinase 1	Homo sapiens (human)
ATP binding	AP2-associated protein kinase 1	Homo sapiens (human)
AP-2 adaptor complex binding	AP2-associated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	AP2-associated protein kinase 1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Myosin light chain kinase 3	Homo sapiens (human)
myosin light chain kinase activity	Myosin light chain kinase 3	Homo sapiens (human)
protein binding	Myosin light chain kinase 3	Homo sapiens (human)
ATP binding	Myosin light chain kinase 3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase SBK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase SBK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase SBK1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)
molecular_function	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
ATP hydrolysis activity	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
ATP-dependent protein folding chaperone	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
disordered domain specific binding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
ATP binding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
unfolded protein binding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
protein binding	Rab-like protein 3	Homo sapiens (human)
GTP binding	Rab-like protein 3	Homo sapiens (human)
protein homodimerization activity	Rab-like protein 3	Homo sapiens (human)
GTPase activity	Rab-like protein 3	Homo sapiens (human)
SNARE binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
magnesium ion binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
actin binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
GTPase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
JUN kinase kinase kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
MAP kinase kinase kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
GTPase activator activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
ATP binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
GTP binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
microtubule binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
tubulin binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
syntaxin-1 binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
signaling receptor complex adaptor activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
clathrin binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
small GTPase binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
GTP-dependent protein kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
peroxidase inhibitor activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
co-receptor binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
identical protein binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein homodimerization activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
transmembrane transporter binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein kinase A binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
beta-catenin destruction complex binding	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
flavin adenine dinucleotide binding	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek5	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek5	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek5	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek5	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Nek5	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase N3	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase N3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase N3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase N3	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase N3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase N3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase N3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein serine/threonine kinase activity	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
protein tyrosine kinase activity	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
protein binding	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
ATP binding	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
protein serine kinase activity	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)
acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
long-chain fatty acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
protein binding	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
very-long-chain fatty acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
flavin adenine dinucleotide binding	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
medium-chain fatty acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
endonuclease activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
RNA endonuclease activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
unfolded protein binding	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
RNA binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
lipid binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein kinase activator activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
chromatin binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
double-stranded RNA binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
G-quadruplex RNA binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
DNA helicase activity	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
transferase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
alpha-tubulin binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
beta-tubulin binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein kinase activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein binding	STE20-related kinase adapter protein alpha	Homo sapiens (human)
ATP binding	STE20-related kinase adapter protein alpha	Homo sapiens (human)
kinase binding	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein kinase activator activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein serine/threonine kinase activator activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
microfilament motor activity	Myosin-14	Homo sapiens (human)
actin filament binding	Myosin-14	Homo sapiens (human)
calmodulin binding	Myosin-14	Homo sapiens (human)
ATP binding	Myosin-14	Homo sapiens (human)
protein serine/threonine kinase activity	AarF domain-containing protein kinase 1	Homo sapiens (human)
ATP binding	AarF domain-containing protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 32C	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 32C	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 32C	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 32C	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 32C	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein domain specific binding	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein binding	Myosin light chain kinase family member 4	Homo sapiens (human)
ATP binding	Myosin light chain kinase family member 4	Homo sapiens (human)
protein serine kinase activity	Myosin light chain kinase family member 4	Homo sapiens (human)
myosin light chain kinase activity	Myosin light chain kinase family member 4	Homo sapiens (human)
protein binding	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
ATP binding	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase-like 3	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase-like 3	Homo sapiens (human)
protein binding	Cyclin-dependent kinase-like 3	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase-like 3	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase-like 3	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase-like 3	Homo sapiens (human)
p53 binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
MAP kinase kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
ATP binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein serine kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
calmodulin-dependent protein kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
mitogen-activated protein kinase binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
calmodulin binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
ATPase binding	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
ATPase regulator activity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase NIM1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase NIM1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase NIM1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase NIM1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
protein kinase activity	Misshapen-like kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Misshapen-like kinase 1	Homo sapiens (human)
protein binding	Misshapen-like kinase 1	Homo sapiens (human)
ATP binding	Misshapen-like kinase 1	Homo sapiens (human)
protein serine kinase activity	Misshapen-like kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
microtubule binding	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
ATP binding	Casein kinase I isoform alpha-like	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform alpha-like	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform alpha-like	Homo sapiens (human)
RNA binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
serine-type endopeptidase activity	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
protein binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
sodium channel inhibitor activity	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
low-density lipoprotein particle binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
signaling receptor inhibitor activity	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
apolipoprotein binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
very-low-density lipoprotein particle binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
apolipoprotein receptor binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
low-density lipoprotein particle receptor binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
very-low-density lipoprotein particle receptor binding	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
protein binding	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
ATP binding	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
histone kinase activity	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
protein serine kinase activity	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
protein tyrosine kinase activity	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
microfilament motor activity	Myosin-IIIa	Homo sapiens (human)
actin binding	Myosin-IIIa	Homo sapiens (human)
protein kinase activity	Myosin-IIIa	Homo sapiens (human)
protein binding	Myosin-IIIa	Homo sapiens (human)
calmodulin binding	Myosin-IIIa	Homo sapiens (human)
ATP binding	Myosin-IIIa	Homo sapiens (human)
ADP binding	Myosin-IIIa	Homo sapiens (human)
plus-end directed microfilament motor activity	Myosin-IIIa	Homo sapiens (human)
protein serine kinase activity	Myosin-IIIa	Homo sapiens (human)
protein serine/threonine kinase activity	Myosin-IIIa	Homo sapiens (human)
protein serine/threonine kinase activity	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
protein binding	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
ATP binding	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
protein serine kinase activity	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
protein kinase activity	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
protein binding	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
ATP binding	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
kinase activity	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
ADP binding	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
ATP binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
identical protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
1-phosphatidylinositol-5-phosphate 4-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
chromatin binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
SH3 domain binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein kinase activator activity	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
gamma-tubulin binding	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 35	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 35	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 35	Homo sapiens (human)
eukaryotic translation initiation factor 2alpha kinase activity	Serine/threonine-protein kinase 35	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
molecular function activator activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
protein binding	Rhodopsin kinase GRK7	Homo sapiens (human)
ATP binding	Rhodopsin kinase GRK7	Homo sapiens (human)
rhodopsin kinase activity	Rhodopsin kinase GRK7	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 32A	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 32A	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 32A	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 32A	Homo sapiens (human)
actin binding	Myosin-IIIb	Homo sapiens (human)
protein binding	Myosin-IIIb	Homo sapiens (human)
ATP binding	Myosin-IIIb	Homo sapiens (human)
protein serine kinase activity	Myosin-IIIb	Homo sapiens (human)
protein serine/threonine kinase activity	Myosin-IIIb	Homo sapiens (human)
microfilament motor activity	Myosin-IIIb	Homo sapiens (human)
DNA binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
chromatin binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
transcription coregulator activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
double-stranded RNA binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nuclease activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
exonuclease activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
poly(A) binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
DNA/RNA helicase activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
magnesium ion binding	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
ATP binding	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
manganese ion binding	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
protein serine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase-like 2	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase-like 2	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase-like 2	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase-like 2	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase-like 2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
calcium channel regulator activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
potassium channel regulator activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
sodium channel regulator activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
chloride channel regulator activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
phosphatidylinositol binding	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
protein kinase activity	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
ATP binding	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
lipid binding	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
ATP hydrolysis activity	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase B	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase B	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Aurora kinase B	Homo sapiens (human)
protein binding	Aurora kinase B	Homo sapiens (human)
ATP binding	Aurora kinase B	Homo sapiens (human)
kinase binding	Aurora kinase B	Homo sapiens (human)
protein serine kinase activity	Aurora kinase B	Homo sapiens (human)
protein serine/threonine kinase activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
ATP binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytoskeletal anchor activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
gamma-tubulin binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
ubiquitin binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
tau protein binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
tau-protein kinase activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein serine kinase activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein tyrosine kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
14-3-3 protein binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 15	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 15	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 15	Homo sapiens (human)
metal ion binding	Cyclin-dependent kinase 15	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 15	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 15	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 15	Homo sapiens (human)
protein serine/threonine kinase activity	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
protein binding	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol binding	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
calcium ion binding	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
p53 binding	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein serine/threonine kinase activity	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein binding	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
ATP binding	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
hydrolase activity	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein serine kinase activity	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein kinase activity	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
protein binding	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
ATP binding	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
metal ion binding	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
magnesium ion binding	SRSF protein kinase 1	Homo sapiens (human)
RNA binding	SRSF protein kinase 1	Homo sapiens (human)
protein kinase activity	SRSF protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	SRSF protein kinase 1	Homo sapiens (human)
protein binding	SRSF protein kinase 1	Homo sapiens (human)
ATP binding	SRSF protein kinase 1	Homo sapiens (human)
protein serine kinase activity	SRSF protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein binding	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
ATP binding	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
metal ion binding	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein serine kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein phosphatase binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein domain specific binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
1-phosphatidylinositol-3-phosphate 5-kinase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
protein binding	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
kinase binding	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
phosphatidylinositol kinase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
1-phosphatidylinositol-5-kinase activity	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
eukaryotic translation initiation factor 2alpha kinase activity	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein binding	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
ATP binding	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
heme binding	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein homodimerization activity	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein serine kinase activity	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
hydrolase activity	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
protein serine/threonine kinase activity	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein binding	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
ATP binding	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
metal ion binding	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine kinase activity	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
calmodulin binding	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 19	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 19	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 19	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 19	Homo sapiens (human)
protein serine/threonine kinase activity	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
calcium channel activity	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
protein binding	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
ATP binding	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
metal ion binding	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
protein serine kinase activity	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
monoatomic cation channel activity	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
magnesium ion binding	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
protein binding	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
ATP binding	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
protein-containing complex binding	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 33	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 33	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 33	Homo sapiens (human)
RNA binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
GTPase activity	Nucleolar GTP-binding protein 1	Homo sapiens (human)
protein binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
GTP binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
preribosome binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein kinase C binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
magnesium ion binding	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein binding	NUAK family SNF1-like kinase 2	Homo sapiens (human)
ATP binding	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein serine kinase activity	NUAK family SNF1-like kinase 2	Homo sapiens (human)
RNA binding	RNA cytidine acetyltransferase	Homo sapiens (human)
protein binding	RNA cytidine acetyltransferase	Homo sapiens (human)
ATP binding	RNA cytidine acetyltransferase	Homo sapiens (human)
N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
tRNA N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
DNA polymerase binding	RNA cytidine acetyltransferase	Homo sapiens (human)
mRNA N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
tRNA binding	RNA cytidine acetyltransferase	Homo sapiens (human)
rRNA cytidine N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
myosin light chain kinase activity	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
protein binding	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
calmodulin binding	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
ATP binding	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
myosin light chain binding	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
protein serine/threonine kinase activity	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
identical protein binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein homodimerization activity	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cadherin binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein kinase inhibitor activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
transferase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
transcription coactivator activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
transcription corepressor activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein kinase activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein binding	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
ATP binding	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
SMAD binding	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
virion binding	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Srms	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Srms	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Srms	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Srms	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Srms	Homo sapiens (human)
protein kinase activity	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
ATP binding	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
protein tyrosine kinase activity	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
p53 binding	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
magnesium ion binding	dCTP pyrophosphatase 1	Homo sapiens (human)
protein binding	dCTP pyrophosphatase 1	Homo sapiens (human)
pyrimidine deoxyribonucleotide binding	dCTP pyrophosphatase 1	Homo sapiens (human)
identical protein binding	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleoside triphosphate diphosphatase activity	dCTP pyrophosphatase 1	Homo sapiens (human)
dCTP diphosphatase activity	dCTP pyrophosphatase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK4	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein serine/threonine kinase activity	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein binding	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
ATP binding	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
metal ion binding	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein serine kinase activity	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
calmodulin-dependent protein kinase activity	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
calmodulin binding	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
transcription corepressor binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
kinesin binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
ubiquitin protein ligase binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
DNA-binding transcription factor binding	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform gamma-1	Homo sapiens (human)
protein binding	Casein kinase I isoform gamma-1	Homo sapiens (human)
ATP binding	Casein kinase I isoform gamma-1	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform gamma-1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
magnesium ion binding	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
transcription corepressor binding	Serine/threonine-protein kinase 36	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 36	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 36	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 36	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 36	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 36	Homo sapiens (human)
magnesium ion binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
RNA binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
phenylalanine-tRNA ligase activity	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
protein binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
ATP binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
tRNA binding	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
aminoacyl-tRNA editing activity	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
isoleucine-tRNA ligase activity	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
ATP binding	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
protein binding	BMP-2-inducible protein kinase	Homo sapiens (human)
ATP binding	BMP-2-inducible protein kinase	Homo sapiens (human)
protein serine kinase activity	BMP-2-inducible protein kinase	Homo sapiens (human)
phosphatase regulator activity	BMP-2-inducible protein kinase	Homo sapiens (human)
AP-2 adaptor complex binding	BMP-2-inducible protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	BMP-2-inducible protein kinase	Homo sapiens (human)
protein binding	Obg-like ATPase 1	Homo sapiens (human)
ATP binding	Obg-like ATPase 1	Homo sapiens (human)
GTP binding	Obg-like ATPase 1	Homo sapiens (human)
ATP hydrolysis activity	Obg-like ATPase 1	Homo sapiens (human)
ribosomal large subunit binding	Obg-like ATPase 1	Homo sapiens (human)
cadherin binding	Obg-like ATPase 1	Homo sapiens (human)
metal ion binding	Obg-like ATPase 1	Homo sapiens (human)
protein binding	Midasin	Homo sapiens (human)
ATP binding	Midasin	Homo sapiens (human)
ATP hydrolysis activity	Midasin	Homo sapiens (human)
magnesium ion binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
interleukin-1 receptor binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
ATP binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
kinase activity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein kinase binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein serine kinase activity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 32B	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 32B	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 32B	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 32B	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
RNA binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein kinase activator activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
ribosome binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
small ribosomal subunit rRNA binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 12	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 12	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
protein kinase binding	Cyclin-dependent kinase 12	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 12	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
ATP-dependent protein binding	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
protein binding	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
ATP binding	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
endopeptidase activator activity	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
phosphatidylserine binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
phosphatidylinositol-4,5-bisphosphate binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
phosphatidic acid binding	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
tRNA binding	eIF-2-alpha kinase GCN2	Homo sapiens (human)
protein serine/threonine kinase activity	eIF-2-alpha kinase GCN2	Homo sapiens (human)
eukaryotic translation initiation factor 2alpha kinase activity	eIF-2-alpha kinase GCN2	Homo sapiens (human)
ATP binding	eIF-2-alpha kinase GCN2	Homo sapiens (human)
protein serine kinase activity	eIF-2-alpha kinase GCN2	Homo sapiens (human)
magnesium ion binding	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate-CoA ligase (ADP-forming) activity	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
protein binding	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
ATP binding	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
MAP kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
ubiquitin protein ligase binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
SH2 domain binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
DNA-binding transcription factor binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
1-phosphatidylinositol 4-kinase activity	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
protein binding	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
ATP binding	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
14-3-3 protein binding	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 17A	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 17A	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 17A	Homo sapiens (human)
protein serine/threonine kinase activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
protein binding	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
ATP binding	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
kinase activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
protein kinase binding	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
protein serine kinase activity	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
molecular_function	Ephrin type-A receptor 6	Homo sapiens (human)
protein binding	Ephrin type-A receptor 6	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 6	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 6	Homo sapiens (human)
AMP-activated protein kinase activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cAMP-dependent protein kinase inhibitor activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cAMP-dependent protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
phosphorylase kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein kinase binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein kinase activator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
ADP binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
AMP binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleic acid binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein phosphatase binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
phosphoprotein binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein binding	Septin-9	Homo sapiens (human)
GTP binding	Septin-9	Homo sapiens (human)
cadherin binding	Septin-9	Homo sapiens (human)
GTPase activity	Septin-9	Homo sapiens (human)
molecular adaptor activity	Septin-9	Homo sapiens (human)
protein serine/threonine kinase activity	Death-associated protein kinase 2	Homo sapiens (human)
protein binding	Death-associated protein kinase 2	Homo sapiens (human)
calmodulin binding	Death-associated protein kinase 2	Homo sapiens (human)
ATP binding	Death-associated protein kinase 2	Homo sapiens (human)
identical protein binding	Death-associated protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Death-associated protein kinase 2	Homo sapiens (human)
A-type (transient outward) potassium channel activity	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
protein binding	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
transmembrane transporter binding	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
metal ion binding	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
voltage-gated potassium channel activity	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein kinase activity	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein kinase activity	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein binding	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
ATP binding	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein serine kinase activity	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
MAP kinase kinase kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
mitogen-activated protein kinase kinase binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
neuropilin binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 14	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 14	Homo sapiens (human)
protein tyrosine kinase activity	ALK tyrosine kinase receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	ALK tyrosine kinase receptor	Homo sapiens (human)
protein binding	ALK tyrosine kinase receptor	Homo sapiens (human)
ATP binding	ALK tyrosine kinase receptor	Homo sapiens (human)
heparin binding	ALK tyrosine kinase receptor	Homo sapiens (human)
receptor signaling protein tyrosine kinase activator activity	ALK tyrosine kinase receptor	Homo sapiens (human)
identical protein binding	ALK tyrosine kinase receptor	Homo sapiens (human)
protein binding	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
ATP binding	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
organic anion transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
ABC-type xenobiotic transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
urate transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
biotin transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
efflux transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
ATP hydrolysis activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
riboflavin transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
ATPase-coupled transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
identical protein binding	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
protein homodimerization activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
xenobiotic transmembrane transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
sphingolipid transporter activity	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
protein binding	SRSF protein kinase 3	Homo sapiens (human)
ATP binding	SRSF protein kinase 3	Homo sapiens (human)
protein serine kinase activity	SRSF protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	SRSF protein kinase 3	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 11A	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 11A	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 11A	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 11A	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 11A	Homo sapiens (human)
protein kinase activity	Aurora kinase C	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase C	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Aurora kinase C	Homo sapiens (human)
protein binding	Aurora kinase C	Homo sapiens (human)
ATP binding	Aurora kinase C	Homo sapiens (human)
protein serine kinase activity	Aurora kinase C	Homo sapiens (human)
protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
glutamate receptor binding	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
identical protein binding	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
protein homodimerization activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
metal ion binding	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
protein kinase activity	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
carbonate dehydratase activity	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
zinc ion binding	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
actin binding	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
magnesium ion binding	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
protein binding	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
ATP binding	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
microtubule binding	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
transcription coregulator activity	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
transcription coactivator activity	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
RNA binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
protein binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
ATP binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear receptor coactivator activity	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear vitamin D receptor binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear thyroid hormone receptor binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
phosphoprotein binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
DNA binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
transcription coactivator activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
ATP binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein serine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
transcription coactivator activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
ATP binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
identical protein binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein-containing complex binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
magnesium ion binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
ATP binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein kinase binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein homodimerization activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein heterodimerization activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform gamma-3	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform gamma-3	Homo sapiens (human)
ATP binding	Casein kinase I isoform gamma-3	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform gamma-3	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (481)

Process	via Protein(s)	Taxonomy
plasma membrane	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
dendrite	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
neuronal cell body	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
receptor complex	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
HFE-transferrin receptor complex	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
plasma membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
extracellular region	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
mitochondrial outer membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
endoplasmic reticulum	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
plasma membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
smooth endoplasmic reticulum membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
specific granule membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
neuron projection	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
neuronal cell body	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
cell body	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
synapse	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
endoplasmic reticulum	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
endomembrane system	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
nucleus	Cell division cycle 7-related protein kinase	Homo sapiens (human)
nucleoplasm	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cytoplasm	Cell division cycle 7-related protein kinase	Homo sapiens (human)
intercellular bridge	Cell division cycle 7-related protein kinase	Homo sapiens (human)
mitotic spindle	Cell division cycle 7-related protein kinase	Homo sapiens (human)
nucleus	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cytoplasm	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cytosol	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex, class IA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)
XY body	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
centriole	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
cleavage furrow	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
deuterosome	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
procentriole	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
procentriole replication complex	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 25	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 25	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 25	Homo sapiens (human)
FAR/SIN/STRIPAK complex	Serine/threonine-protein kinase 25	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 25	Homo sapiens (human)
eukaryotic translation initiation factor 3 complex	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytosolic small ribosomal subunit	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extracellular region	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleoplasm	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
centrosome	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
plasma membrane	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytoplasmic stress granule	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
lamellipodium	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cell leading edge	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
secretory granule lumen	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extracellular exosome	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ficolin-1-rich granule lumen	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
NLRP3 inflammasome complex	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
P granule	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
endoplasmic reticulum	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
cytosol	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
endocytic vesicle	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
intracellular membrane-bounded organelle	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
phosphatidylinositol 3-kinase complex	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)
extracellular region	Pyridoxal kinase	Homo sapiens (human)
nucleus	Pyridoxal kinase	Homo sapiens (human)
nucleoplasm	Pyridoxal kinase	Homo sapiens (human)
cytosol	Pyridoxal kinase	Homo sapiens (human)
secretory granule lumen	Pyridoxal kinase	Homo sapiens (human)
specific granule lumen	Pyridoxal kinase	Homo sapiens (human)
extracellular exosome	Pyridoxal kinase	Homo sapiens (human)
cytosol	Pyridoxal kinase	Homo sapiens (human)
cytosol	Citron Rho-interacting kinase	Homo sapiens (human)
membrane	Citron Rho-interacting kinase	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
preribosome, small subunit precursor	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase RIO3	Homo sapiens (human)
nucleus	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
cytoplasm	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)
chromosome, telomeric region	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
condensed nuclear chromosome	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
extracellular space	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
replication fork	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
intracellular membrane-bounded organelle	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
chromatin	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
nucleus	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
cytosol	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
IkappaB kinase complex	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
cytoplasmic side of plasma membrane	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
membrane raft	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
CD40 receptor complex	Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)
basement membrane	Peripheral plasma membrane protein CASK	Homo sapiens (human)
nuclear lamina	Peripheral plasma membrane protein CASK	Homo sapiens (human)
nucleolus	Peripheral plasma membrane protein CASK	Homo sapiens (human)
cytoplasm	Peripheral plasma membrane protein CASK	Homo sapiens (human)
cytosol	Peripheral plasma membrane protein CASK	Homo sapiens (human)
cell-cell junction	Peripheral plasma membrane protein CASK	Homo sapiens (human)
focal adhesion	Peripheral plasma membrane protein CASK	Homo sapiens (human)
actin cytoskeleton	Peripheral plasma membrane protein CASK	Homo sapiens (human)
nuclear matrix	Peripheral plasma membrane protein CASK	Homo sapiens (human)
vesicle	Peripheral plasma membrane protein CASK	Homo sapiens (human)
presynaptic membrane	Peripheral plasma membrane protein CASK	Homo sapiens (human)
ciliary membrane	Peripheral plasma membrane protein CASK	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Peripheral plasma membrane protein CASK	Homo sapiens (human)
basement membrane	Peripheral plasma membrane protein CASK	Homo sapiens (human)
cell-cell junction	Peripheral plasma membrane protein CASK	Homo sapiens (human)
basolateral plasma membrane	Peripheral plasma membrane protein CASK	Homo sapiens (human)
plasma membrane	Peripheral plasma membrane protein CASK	Homo sapiens (human)
spindle microtubule	Aurora kinase A	Homo sapiens (human)
nucleus	Aurora kinase A	Homo sapiens (human)
nucleoplasm	Aurora kinase A	Homo sapiens (human)
centrosome	Aurora kinase A	Homo sapiens (human)
centriole	Aurora kinase A	Homo sapiens (human)
spindle	Aurora kinase A	Homo sapiens (human)
cytosol	Aurora kinase A	Homo sapiens (human)
postsynaptic density	Aurora kinase A	Homo sapiens (human)
microtubule cytoskeleton	Aurora kinase A	Homo sapiens (human)
basolateral plasma membrane	Aurora kinase A	Homo sapiens (human)
midbody	Aurora kinase A	Homo sapiens (human)
spindle pole centrosome	Aurora kinase A	Homo sapiens (human)
ciliary basal body	Aurora kinase A	Homo sapiens (human)
germinal vesicle	Aurora kinase A	Homo sapiens (human)
axon hillock	Aurora kinase A	Homo sapiens (human)
pronucleus	Aurora kinase A	Homo sapiens (human)
perinuclear region of cytoplasm	Aurora kinase A	Homo sapiens (human)
mitotic spindle	Aurora kinase A	Homo sapiens (human)
meiotic spindle	Aurora kinase A	Homo sapiens (human)
mitotic spindle pole	Aurora kinase A	Homo sapiens (human)
glutamatergic synapse	Aurora kinase A	Homo sapiens (human)
spindle pole centrosome	Aurora kinase A	Homo sapiens (human)
chromosome passenger complex	Aurora kinase A	Homo sapiens (human)
spindle midzone	Aurora kinase A	Homo sapiens (human)
kinetochore	Aurora kinase A	Homo sapiens (human)
Golgi apparatus	Cyclin-G-associated kinase	Homo sapiens (human)
cytosol	Cyclin-G-associated kinase	Homo sapiens (human)
focal adhesion	Cyclin-G-associated kinase	Homo sapiens (human)
membrane	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin-coated vesicle	Cyclin-G-associated kinase	Homo sapiens (human)
vesicle	Cyclin-G-associated kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	Cyclin-G-associated kinase	Homo sapiens (human)
perinuclear region of cytoplasm	Cyclin-G-associated kinase	Homo sapiens (human)
presynapse	Cyclin-G-associated kinase	Homo sapiens (human)
vesicle	Cyclin-G-associated kinase	Homo sapiens (human)
cytoplasm	Cyclin-G-associated kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	Cyclin-G-associated kinase	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
postsynaptic density	Serine/threonine-protein kinase DCLK1	Homo sapiens (human)
nucleoplasm	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cytosol	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
IkappaB kinase complex	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cytoplasmic side of plasma membrane	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
CD40 receptor complex	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)
plasma membrane	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
neuromuscular junction	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
postsynaptic membrane	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
receptor complex	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
plasma membrane	Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 6	Homo sapiens (human)
cytosol	Ephrin type-B receptor 6	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 6	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 6	Homo sapiens (human)
dendrite	Ephrin type-B receptor 6	Homo sapiens (human)
peroxisome	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
peroxisomal matrix	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
cytosol	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
membrane	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
peroxisome	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 13	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 13	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 13	Homo sapiens (human)
nucleus	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cytoplasm	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cytosol	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
plasma membrane	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
focal adhesion	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
postsynaptic density	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cytoplasmic vesicle	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cell projection	3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
membrane	Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)
nucleus	Death-associated protein kinase 3	Homo sapiens (human)
nucleoplasm	Death-associated protein kinase 3	Homo sapiens (human)
cytosol	Death-associated protein kinase 3	Homo sapiens (human)
PML body	Death-associated protein kinase 3	Homo sapiens (human)
nucleus	Death-associated protein kinase 3	Homo sapiens (human)
cytoplasm	Death-associated protein kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
endosome membrane	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
ATAC complex	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)
plasma membrane	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytoplasm	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
endoplasmic reticulum	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytosol	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytoskeleton	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
vesicle	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein-containing complex	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 12	Homo sapiens (human)
membrane	Carbonic anhydrase 12	Homo sapiens (human)
basolateral plasma membrane	Carbonic anhydrase 12	Homo sapiens (human)
apical plasma membrane	Carbonic anhydrase 12	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 12	Homo sapiens (human)
kinetochore	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
nucleoplasm	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
cytosol	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
membrane	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
intracellular membrane-bounded organelle	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
outer kinetochore	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
kinetochore	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
nucleus	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
fibrillar center	NUAK family SNF1-like kinase 1	Homo sapiens (human)
nucleus	NUAK family SNF1-like kinase 1	Homo sapiens (human)
nucleoplasm	NUAK family SNF1-like kinase 1	Homo sapiens (human)
cytoplasm	NUAK family SNF1-like kinase 1	Homo sapiens (human)
microtubule cytoskeleton	NUAK family SNF1-like kinase 1	Homo sapiens (human)
nucleoplasm	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial outer membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial intermembrane space	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cytosol	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial crista	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
dendrite	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
axon cytoplasm	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial intermembrane space	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cytoplasm	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
microtubule	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
phagocytic cup	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
uropod	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
cytosol	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
adherens junction	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
focal adhesion	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
endosome membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
ruffle membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
presynapse	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)
extrinsic component of plasma membrane	Tyrosine-protein kinase JAK2	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK2	Homo sapiens (human)
nucleus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase JAK2	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase JAK2	Homo sapiens (human)
caveola	Tyrosine-protein kinase JAK2	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
granulocyte macrophage colony-stimulating factor receptor complex	Tyrosine-protein kinase JAK2	Homo sapiens (human)
endosome lumen	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-12 receptor complex	Tyrosine-protein kinase JAK2	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-23 receptor complex	Tyrosine-protein kinase JAK2	Homo sapiens (human)
postsynapse	Tyrosine-protein kinase JAK2	Homo sapiens (human)
glutamatergic synapse	Tyrosine-protein kinase JAK2	Homo sapiens (human)
euchromatin	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK2	Homo sapiens (human)
photoreceptor outer segment	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
membrane	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
perikaryon	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)
nucleus	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
cytoplasm	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
cytosol	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
synapse	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
cytoplasm	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
nucleus	Rho-associated protein kinase 2	Homo sapiens (human)
centrosome	Rho-associated protein kinase 2	Homo sapiens (human)
cytosol	Rho-associated protein kinase 2	Homo sapiens (human)
plasma membrane	Rho-associated protein kinase 2	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Rho-associated protein kinase 2	Homo sapiens (human)
centrosome	Rho-associated protein kinase 2	Homo sapiens (human)
cytoskeleton	Rho-associated protein kinase 2	Homo sapiens (human)
cytoplasm	Rho-associated protein kinase 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagosome membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
mitochondrial outer membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
axon	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
recycling endosome	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
omegasome membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
Atg1/ULK1 kinase complex	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
nuclear inner membrane	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
endoplasmic reticulum	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
Ire1 complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
AIP1-IRE1 complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
IRE1-TRAF2-ASK1 complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
IRE1-RACK1-PP2A complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
nucleus	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
nucleus	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
nucleoplasm	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
membrane	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U4/U6 x U5 tri-snRNP complex	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
spliceosomal complex	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U5 snRNP	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U2-type precatalytic spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U2-type catalytic step 1 spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
catalytic step 2 spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
nucleus	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 16	Homo sapiens (human)
Golgi-associated vesicle	Serine/threonine-protein kinase 16	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 16	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 16	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase 16	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 16	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 16	Homo sapiens (human)
cytosol	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
membrane	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
phosphatidylinositol 3-kinase complex	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)
nuclear outer membrane	Solute carrier family 22 member 3	Homo sapiens (human)
plasma membrane	Solute carrier family 22 member 3	Homo sapiens (human)
endomembrane system	Solute carrier family 22 member 3	Homo sapiens (human)
membrane	Solute carrier family 22 member 3	Homo sapiens (human)
basolateral plasma membrane	Solute carrier family 22 member 3	Homo sapiens (human)
apical plasma membrane	Solute carrier family 22 member 3	Homo sapiens (human)
mitochondrial membrane	Solute carrier family 22 member 3	Homo sapiens (human)
neuronal cell body	Solute carrier family 22 member 3	Homo sapiens (human)
presynapse	Solute carrier family 22 member 3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
postsynaptic density	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
glutamatergic synapse	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 3	Homo sapiens (human)
ruffle membrane	Cyclin-dependent kinase-like 5	Homo sapiens (human)
glutamatergic synapse	Cyclin-dependent kinase-like 5	Homo sapiens (human)
nucleus	Cyclin-dependent kinase-like 5	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase-like 5	Homo sapiens (human)
centrosome	Cyclin-dependent kinase-like 5	Homo sapiens (human)
dendrite cytoplasm	Cyclin-dependent kinase-like 5	Homo sapiens (human)
ciliary basal body	Cyclin-dependent kinase-like 5	Homo sapiens (human)
dendritic growth cone	Cyclin-dependent kinase-like 5	Homo sapiens (human)
perinuclear region of cytoplasm	Cyclin-dependent kinase-like 5	Homo sapiens (human)
ciliary tip	Cyclin-dependent kinase-like 5	Homo sapiens (human)
postsynaptic density, intracellular component	Cyclin-dependent kinase-like 5	Homo sapiens (human)
nucleus	Cyclin-dependent kinase-like 5	Homo sapiens (human)
dendrite cytoplasm	Cyclin-dependent kinase-like 5	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 17B	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 17B	Homo sapiens (human)
endoplasmic reticulum-Golgi intermediate compartment	Serine/threonine-protein kinase 17B	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 17B	Homo sapiens (human)
actin cytoskeleton	Serine/threonine-protein kinase 17B	Homo sapiens (human)
Flemming body	Serine/threonine-protein kinase 17B	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 17B	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 10	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 10	Homo sapiens (human)
specific granule membrane	Serine/threonine-protein kinase 10	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 10	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 10	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D3	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D3	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 14	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 14	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 14	Homo sapiens (human)
plasma membrane	Cyclin-dependent kinase 14	Homo sapiens (human)
cytoplasmic cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 14	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 14	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 14	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 14	Homo sapiens (human)
nuclear chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensed chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensed nuclear chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensin complex	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
nucleus	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
nucleoplasm	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
nucleolus	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cytoplasm	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cytosol	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
extracellular exosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensed chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
chromatin	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase OSR1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
focal adhesion	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
midbody	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
adherens junction	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
focal adhesion	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
chromosome, telomeric region	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
PML body	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Chk2	Homo sapiens (human)
ruffle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nucleus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nucleolus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitochondrion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nuclear body	Tyrosine-protein kinase ABL1	Homo sapiens (human)
dendrite	Tyrosine-protein kinase ABL1	Homo sapiens (human)
growth cone	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nuclear membrane	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuronal cell body	Tyrosine-protein kinase ABL1	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase ABL1	Homo sapiens (human)
postsynapse	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein-containing complex	Tyrosine-protein kinase ABL1	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cytosol	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
nucleus	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
mitochondrial inner membrane	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
cytoskeleton	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
focal adhesion	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
endosome membrane	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
membrane	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
cell junction	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
perinuclear region of cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
protein-containing complex	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)
endosome	Epidermal growth factor receptor	Homo sapiens (human)
plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
ruffle membrane	Epidermal growth factor receptor	Homo sapiens (human)
Golgi membrane	Epidermal growth factor receptor	Homo sapiens (human)
extracellular space	Epidermal growth factor receptor	Homo sapiens (human)
nucleus	Epidermal growth factor receptor	Homo sapiens (human)
cytoplasm	Epidermal growth factor receptor	Homo sapiens (human)
endosome	Epidermal growth factor receptor	Homo sapiens (human)
endoplasmic reticulum membrane	Epidermal growth factor receptor	Homo sapiens (human)
plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
focal adhesion	Epidermal growth factor receptor	Homo sapiens (human)
cell surface	Epidermal growth factor receptor	Homo sapiens (human)
endosome membrane	Epidermal growth factor receptor	Homo sapiens (human)
membrane	Epidermal growth factor receptor	Homo sapiens (human)
basolateral plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
apical plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
cell junction	Epidermal growth factor receptor	Homo sapiens (human)
clathrin-coated endocytic vesicle membrane	Epidermal growth factor receptor	Homo sapiens (human)
early endosome membrane	Epidermal growth factor receptor	Homo sapiens (human)
nuclear membrane	Epidermal growth factor receptor	Homo sapiens (human)
membrane raft	Epidermal growth factor receptor	Homo sapiens (human)
perinuclear region of cytoplasm	Epidermal growth factor receptor	Homo sapiens (human)
multivesicular body, internal vesicle lumen	Epidermal growth factor receptor	Homo sapiens (human)
intracellular vesicle	Epidermal growth factor receptor	Homo sapiens (human)
protein-containing complex	Epidermal growth factor receptor	Homo sapiens (human)
receptor complex	Epidermal growth factor receptor	Homo sapiens (human)
Shc-EGFR complex	Epidermal growth factor receptor	Homo sapiens (human)
basal plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
cytosol	Carbonic anhydrase 1	Homo sapiens (human)
extracellular exosome	Carbonic anhydrase 1	Homo sapiens (human)
cytoplasm	Carbonic anhydrase 2	Homo sapiens (human)
cytosol	Carbonic anhydrase 2	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 2	Homo sapiens (human)
myelin sheath	Carbonic anhydrase 2	Homo sapiens (human)
apical part of cell	Carbonic anhydrase 2	Homo sapiens (human)
extracellular exosome	Carbonic anhydrase 2	Homo sapiens (human)
cytoplasm	Carbonic anhydrase 2	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 2	Homo sapiens (human)
apical part of cell	Carbonic anhydrase 2	Homo sapiens (human)
lysosome	Low-density lipoprotein receptor	Homo sapiens (human)
early endosome	Low-density lipoprotein receptor	Homo sapiens (human)
late endosome	Low-density lipoprotein receptor	Homo sapiens (human)
Golgi apparatus	Low-density lipoprotein receptor	Homo sapiens (human)
plasma membrane	Low-density lipoprotein receptor	Homo sapiens (human)
clathrin-coated pit	Low-density lipoprotein receptor	Homo sapiens (human)
external side of plasma membrane	Low-density lipoprotein receptor	Homo sapiens (human)
cell surface	Low-density lipoprotein receptor	Homo sapiens (human)
endosome membrane	Low-density lipoprotein receptor	Homo sapiens (human)
membrane	Low-density lipoprotein receptor	Homo sapiens (human)
basolateral plasma membrane	Low-density lipoprotein receptor	Homo sapiens (human)
clathrin-coated endocytic vesicle membrane	Low-density lipoprotein receptor	Homo sapiens (human)
endolysosome membrane	Low-density lipoprotein receptor	Homo sapiens (human)
somatodendritic compartment	Low-density lipoprotein receptor	Homo sapiens (human)
apical part of cell	Low-density lipoprotein receptor	Homo sapiens (human)
sorting endosome	Low-density lipoprotein receptor	Homo sapiens (human)
PCSK9-LDLR complex	Low-density lipoprotein receptor	Homo sapiens (human)
low-density lipoprotein particle	Low-density lipoprotein receptor	Homo sapiens (human)
receptor complex	Low-density lipoprotein receptor	Homo sapiens (human)
early endosome	Low-density lipoprotein receptor	Homo sapiens (human)
plasma membrane	Low-density lipoprotein receptor	Homo sapiens (human)
collagen-containing extracellular matrix	Fibronectin	Homo sapiens (human)
extracellular matrix	Fibronectin	Homo sapiens (human)
extracellular region	Fibronectin	Homo sapiens (human)
fibrinogen complex	Fibronectin	Homo sapiens (human)
basement membrane	Fibronectin	Homo sapiens (human)
extracellular space	Fibronectin	Homo sapiens (human)
endoplasmic reticulum lumen	Fibronectin	Homo sapiens (human)
endoplasmic reticulum-Golgi intermediate compartment	Fibronectin	Homo sapiens (human)
plasma membrane	Fibronectin	Homo sapiens (human)
apical plasma membrane	Fibronectin	Homo sapiens (human)
platelet alpha granule lumen	Fibronectin	Homo sapiens (human)
collagen-containing extracellular matrix	Fibronectin	Homo sapiens (human)
extracellular exosome	Fibronectin	Homo sapiens (human)
blood microparticle	Fibronectin	Homo sapiens (human)
plasma membrane	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
nucleus	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
mitochondrial outer membrane	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
Golgi apparatus	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
cytosol	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
pseudopodium	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
cytosol	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
mitochondrion	RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)
semaphorin receptor complex	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
nucleus	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
nucleoplasm	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
early endosome	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
cytosol	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
plasma membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
endosome membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
basolateral plasma membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
apical plasma membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
neuromuscular junction	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ruffle membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
presynaptic membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
myelin sheath	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
perinuclear region of cytoplasm	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
ERBB3:ERBB2 complex	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
receptor complex	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
plasma membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
basal plasma membrane	Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)
early endosome	High affinity nerve growth factor receptor	Homo sapiens (human)
late endosome	High affinity nerve growth factor receptor	Homo sapiens (human)
plasma membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
cell surface	High affinity nerve growth factor receptor	Homo sapiens (human)
endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
dendrite	High affinity nerve growth factor receptor	Homo sapiens (human)
early endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
late endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
neuronal cell body	High affinity nerve growth factor receptor	Homo sapiens (human)
recycling endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
protein-containing complex	High affinity nerve growth factor receptor	Homo sapiens (human)
receptor complex	High affinity nerve growth factor receptor	Homo sapiens (human)
axon	High affinity nerve growth factor receptor	Homo sapiens (human)
plasma membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
nucleus	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrion	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial inner membrane	ADP/ATP translocase 2	Homo sapiens (human)
plasma membrane	ADP/ATP translocase 2	Homo sapiens (human)
membrane	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial nucleoid	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial permeability transition pore complex	ADP/ATP translocase 2	Homo sapiens (human)
MMXD complex	ADP/ATP translocase 2	Homo sapiens (human)
nucleus	Protein kinase C beta type	Homo sapiens (human)
nucleoplasm	Protein kinase C beta type	Homo sapiens (human)
cytoplasm	Protein kinase C beta type	Homo sapiens (human)
centrosome	Protein kinase C beta type	Homo sapiens (human)
cytosol	Protein kinase C beta type	Homo sapiens (human)
plasma membrane	Protein kinase C beta type	Homo sapiens (human)
brush border membrane	Protein kinase C beta type	Homo sapiens (human)
calyx of Held	Protein kinase C beta type	Homo sapiens (human)
extracellular exosome	Protein kinase C beta type	Homo sapiens (human)
presynaptic cytosol	Protein kinase C beta type	Homo sapiens (human)
spectrin	Protein kinase C beta type	Homo sapiens (human)
nuclear envelope	Insulin receptor	Homo sapiens (human)
nuclear lumen	Insulin receptor	Homo sapiens (human)
lysosome	Insulin receptor	Homo sapiens (human)
late endosome	Insulin receptor	Homo sapiens (human)
plasma membrane	Insulin receptor	Homo sapiens (human)
caveola	Insulin receptor	Homo sapiens (human)
external side of plasma membrane	Insulin receptor	Homo sapiens (human)
endosome membrane	Insulin receptor	Homo sapiens (human)
membrane	Insulin receptor	Homo sapiens (human)
dendrite membrane	Insulin receptor	Homo sapiens (human)
neuronal cell body membrane	Insulin receptor	Homo sapiens (human)
extracellular exosome	Insulin receptor	Homo sapiens (human)
insulin receptor complex	Insulin receptor	Homo sapiens (human)
receptor complex	Insulin receptor	Homo sapiens (human)
plasma membrane	Insulin receptor	Homo sapiens (human)
axon	Insulin receptor	Homo sapiens (human)
pericentriolar material	Tyrosine-protein kinase Lck	Homo sapiens (human)
immunological synapse	Tyrosine-protein kinase Lck	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Lck	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lck	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Lck	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Lck	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lck	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite	Tyrosine-protein kinase Fyn	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
mitochondrion	Tyrosine-protein kinase Fyn	Homo sapiens (human)
endosome	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fyn	Homo sapiens (human)
actin filament	Tyrosine-protein kinase Fyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
postsynaptic density	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perikaryon	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell body	Tyrosine-protein kinase Fyn	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perinuclear endoplasmic reticulum	Tyrosine-protein kinase Fyn	Homo sapiens (human)
glial cell projection	Tyrosine-protein kinase Fyn	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Tyrosine-protein kinase Fyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
mitochondrial matrix	Cyclin-dependent kinase 1	Homo sapiens (human)
chromosome, telomeric region	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 1	Homo sapiens (human)
mitochondrion	Cyclin-dependent kinase 1	Homo sapiens (human)
endoplasmic reticulum membrane	Cyclin-dependent kinase 1	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 1	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 1	Homo sapiens (human)
spindle microtubule	Cyclin-dependent kinase 1	Homo sapiens (human)
membrane	Cyclin-dependent kinase 1	Homo sapiens (human)
midbody	Cyclin-dependent kinase 1	Homo sapiens (human)
extracellular exosome	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic spindle	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin A1-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin A2-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin B1-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
extracellular region	Glycogen phosphorylase, liver form	Homo sapiens (human)
cytosol	Glycogen phosphorylase, liver form	Homo sapiens (human)
secretory granule lumen	Glycogen phosphorylase, liver form	Homo sapiens (human)
extracellular exosome	Glycogen phosphorylase, liver form	Homo sapiens (human)
ficolin-1-rich granule lumen	Glycogen phosphorylase, liver form	Homo sapiens (human)
cytoplasm	Glycogen phosphorylase, liver form	Homo sapiens (human)
cytoplasmic vesicle	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
microtubule cytoskeleton	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
nucleoplasm	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
plasma membrane	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cell surface	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
intracellular membrane-bounded organelle	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
CSF1-CSF1R complex	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
receptor complex	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
plasma membrane	Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)
cytosol	Carbonic anhydrase 3	Homo sapiens (human)
cytosol	Carbonic anhydrase 3	Homo sapiens (human)
cytoplasm	Carbonic anhydrase 3	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Yes	Homo sapiens (human)
centrosome	Tyrosine-protein kinase Yes	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Yes	Homo sapiens (human)
actin filament	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Yes	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase Yes	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Lyn	Homo sapiens (human)
lysosomal membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Lyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
adherens junction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
mitochondrial crista	Tyrosine-protein kinase Lyn	Homo sapiens (human)
endocytic vesicle membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase Lyn	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Lyn	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase Lyn	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Lyn	Homo sapiens (human)
glutamatergic synapse	Tyrosine-protein kinase Lyn	Homo sapiens (human)
postsynaptic specialization, intracellular component	Tyrosine-protein kinase Lyn	Homo sapiens (human)
integrin alpha2-beta1 complex	Tyrosine-protein kinase Lyn	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
early endosome	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
endosome membrane	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
dendrite	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neuronal cell body	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
receptor complex	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
plasma membrane protein complex	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
axon	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
plasma membrane	Insulin-like growth factor 1 receptor	Homo sapiens (human)
caveola	Insulin-like growth factor 1 receptor	Homo sapiens (human)
membrane	Insulin-like growth factor 1 receptor	Homo sapiens (human)
T-tubule	Insulin-like growth factor 1 receptor	Homo sapiens (human)
neuronal cell body	Insulin-like growth factor 1 receptor	Homo sapiens (human)
intracellular membrane-bounded organelle	Insulin-like growth factor 1 receptor	Homo sapiens (human)
alphav-beta3 integrin-IGF-1-IGF1R complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
receptor complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein kinase complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
axon	Insulin-like growth factor 1 receptor	Homo sapiens (human)
plasma membrane	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
signal recognition particle receptor complex	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
extracellular exosome	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
nucleus	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
mitochondrion	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
mitochondrial respiratory chain complex III	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
membrane	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
extracellular region	Hepatocyte growth factor receptor	Homo sapiens (human)
plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
basal plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface	Hepatocyte growth factor receptor	Homo sapiens (human)
membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
postsynapse	Hepatocyte growth factor receptor	Homo sapiens (human)
basal plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
receptor complex	Hepatocyte growth factor receptor	Homo sapiens (human)
actin filament	Tyrosine-protein kinase HCK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase HCK	Homo sapiens (human)
lysosome	Tyrosine-protein kinase HCK	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase HCK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
caveola	Tyrosine-protein kinase HCK	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
transport vesicle	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell projection	Tyrosine-protein kinase HCK	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase HCK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytoplasm	Cytochrome P450 3A4	Homo sapiens (human)
endoplasmic reticulum membrane	Cytochrome P450 3A4	Homo sapiens (human)
intracellular membrane-bounded organelle	Cytochrome P450 3A4	Homo sapiens (human)
membrane	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
receptor complex	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)
plasma membrane	Macrophage colony-stimulating factor 1 receptor	Mus musculus (house mouse)
nucleus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoplasm	Platelet-derived growth factor receptor beta	Homo sapiens (human)
Golgi apparatus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
focal adhesion	Platelet-derived growth factor receptor beta	Homo sapiens (human)
membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
apical plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoplasmic vesicle	Platelet-derived growth factor receptor beta	Homo sapiens (human)
lysosomal lumen	Platelet-derived growth factor receptor beta	Homo sapiens (human)
intracellular membrane-bounded organelle	Platelet-derived growth factor receptor beta	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
receptor complex	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase Fgr	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase Fgr	Homo sapiens (human)
ruffle membrane	Tyrosine-protein kinase Fgr	Homo sapiens (human)
extracellular region	Tyrosine-protein kinase Fgr	Homo sapiens (human)
mitochondrial inner membrane	Tyrosine-protein kinase Fgr	Homo sapiens (human)
mitochondrial intermembrane space	Tyrosine-protein kinase Fgr	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fgr	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fgr	Homo sapiens (human)
aggresome	Tyrosine-protein kinase Fgr	Homo sapiens (human)
secretory granule lumen	Tyrosine-protein kinase Fgr	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Fgr	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fgr	Homo sapiens (human)
nucleoplasm	Wee1-like protein kinase 2	Homo sapiens (human)
cytosol	Wee1-like protein kinase 2	Homo sapiens (human)
plasma membrane	Wee1-like protein kinase 2	Homo sapiens (human)
cytoplasm	Wee1-like protein kinase 2	Homo sapiens (human)
nucleus	Wee1-like protein kinase 2	Homo sapiens (human)
cellular_component	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
fibrillar center	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
acrosomal vesicle	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
extracellular space	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cell-cell junction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
external side of plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cytoplasmic side of plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
receptor complex	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
extracellular region	Glycogen phosphorylase, brain form	Homo sapiens (human)
cytoplasm	Glycogen phosphorylase, brain form	Homo sapiens (human)
membrane	Glycogen phosphorylase, brain form	Homo sapiens (human)
azurophil granule lumen	Glycogen phosphorylase, brain form	Homo sapiens (human)
extracellular exosome	Glycogen phosphorylase, brain form	Homo sapiens (human)
cytoplasm	Glycogen phosphorylase, brain form	Homo sapiens (human)
cytosol	Breakpoint cluster region protein	Homo sapiens (human)
plasma membrane	Breakpoint cluster region protein	Homo sapiens (human)
postsynaptic density	Breakpoint cluster region protein	Homo sapiens (human)
membrane	Breakpoint cluster region protein	Homo sapiens (human)
axon	Breakpoint cluster region protein	Homo sapiens (human)
dendritic spine	Breakpoint cluster region protein	Homo sapiens (human)
extracellular exosome	Breakpoint cluster region protein	Homo sapiens (human)
protein-containing complex	Breakpoint cluster region protein	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Breakpoint cluster region protein	Homo sapiens (human)
glutamatergic synapse	Breakpoint cluster region protein	Homo sapiens (human)
membrane	Breakpoint cluster region protein	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
extracellular region	Fibroblast growth factor receptor 1	Homo sapiens (human)
nucleus	Fibroblast growth factor receptor 1	Homo sapiens (human)
cytosol	Fibroblast growth factor receptor 1	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 1	Homo sapiens (human)
membrane	Fibroblast growth factor receptor 1	Homo sapiens (human)
cytoplasmic vesicle	Fibroblast growth factor receptor 1	Homo sapiens (human)
receptor complex	Fibroblast growth factor receptor 1	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 1	Homo sapiens (human)
nucleolus	DNA topoisomerase 2-alpha	Homo sapiens (human)
nuclear chromosome	DNA topoisomerase 2-alpha	Homo sapiens (human)
centriole	DNA topoisomerase 2-alpha	Homo sapiens (human)
chromosome, centromeric region	DNA topoisomerase 2-alpha	Homo sapiens (human)
condensed chromosome	DNA topoisomerase 2-alpha	Homo sapiens (human)
male germ cell nucleus	DNA topoisomerase 2-alpha	Homo sapiens (human)
nucleus	DNA topoisomerase 2-alpha	Homo sapiens (human)
nucleoplasm	DNA topoisomerase 2-alpha	Homo sapiens (human)
nucleolus	DNA topoisomerase 2-alpha	Homo sapiens (human)
cytoplasm	DNA topoisomerase 2-alpha	Homo sapiens (human)
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	DNA topoisomerase 2-alpha	Homo sapiens (human)
protein-containing complex	DNA topoisomerase 2-alpha	Homo sapiens (human)
ribonucleoprotein complex	DNA topoisomerase 2-alpha	Homo sapiens (human)
nucleus	DNA topoisomerase 2-alpha	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleolus	Cyclin-dependent kinase 4	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 4	Homo sapiens (human)
bicellular tight junction	Cyclin-dependent kinase 4	Homo sapiens (human)
nuclear membrane	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin D1-CDK4 complex	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin D2-CDK4 complex	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin D3-CDK4 complex	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 4	Homo sapiens (human)
chromatin	Cyclin-dependent kinase 4	Homo sapiens (human)
transcription regulator complex	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 4	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleus	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrion	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrial inner membrane	ADP/ATP translocase 3	Homo sapiens (human)
membrane	ADP/ATP translocase 3	Homo sapiens (human)
TIM23 mitochondrial import inner membrane translocase complex	ADP/ATP translocase 3	Homo sapiens (human)
extracellular region	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
nucleus	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cytoplasm	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
peroxisomal membrane	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cytosol	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
membrane	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
secretory granule lumen	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
extracellular exosome	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
ficolin-1-rich granule lumen	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cytoplasm	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
podosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nucleoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
mitochondrion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
mitochondrial inner membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
lysosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
late endosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cytosol	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
actin filament	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
caveola	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
focal adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell junction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ruffle membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
neuronal cell body	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
dendritic growth cone	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
membrane raft	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
perinuclear region of cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
extracellular exosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
synaptic membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
glutamatergic synapse	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
postsynaptic specialization, intracellular component	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
dendritic filopodium	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
axoneme	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
centrosome	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
plasma membrane	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
focal adhesion	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
membrane	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
plasma membrane raft	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
extracellular exosome	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
nucleotide-activated protein kinase complex	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein-containing complex	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
plasma membrane	Solute carrier family 2, facilitated glucose transporter member 4	Mus musculus (house mouse)
cytoplasmic vesicle membrane	Solute carrier family 2, facilitated glucose transporter member 4	Mus musculus (house mouse)
plasma membrane	Insulin receptor-related protein	Homo sapiens (human)
receptor complex	Insulin receptor-related protein	Homo sapiens (human)
insulin receptor complex	Insulin receptor-related protein	Homo sapiens (human)
plasma membrane	Insulin receptor-related protein	Homo sapiens (human)
axon	Insulin receptor-related protein	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
neuron projection	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
intracellular membrane-bounded organelle	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cell body	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
presynapse	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
voltage-gated potassium channel complex	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
lysosome	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cell surface	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
apical plasma membrane	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
Z disc	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
membrane raft	Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)
cytosol	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
phosphorylase kinase complex	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
nucleoplasm	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
cytosol	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
extracellular exosome	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
cytosol	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
nucleus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
nucleoplasm	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cytoplasm	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
Golgi apparatus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
microvillus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cilium	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
external side of plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell junction	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein-containing complex	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
receptor complex	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase Fer	Homo sapiens (human)
microtubule cytoskeleton	Tyrosine-protein kinase Fer	Homo sapiens (human)
lamellipodium	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell junction	Tyrosine-protein kinase Fer	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fer	Homo sapiens (human)
adherens junction	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell cortex	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Fer	Homo sapiens (human)
chromatin	Tyrosine-protein kinase Fer	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fer	Homo sapiens (human)
ciliary basal body	Protein kinase C alpha type	Homo sapiens (human)
nucleoplasm	Protein kinase C alpha type	Homo sapiens (human)
cytoplasm	Protein kinase C alpha type	Homo sapiens (human)
mitochondrion	Protein kinase C alpha type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C alpha type	Homo sapiens (human)
cytosol	Protein kinase C alpha type	Homo sapiens (human)
plasma membrane	Protein kinase C alpha type	Homo sapiens (human)
mitochondrial membrane	Protein kinase C alpha type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C alpha type	Homo sapiens (human)
extracellular exosome	Protein kinase C alpha type	Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complex	Protein kinase C alpha type	Homo sapiens (human)
axoneme	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
acrosomal vesicle	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
mitochondrial matrix	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
centrosome	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
plasma membrane	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nuclear speck	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
neuromuscular junction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
sperm flagellum	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
dendritic spine	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
plasma membrane raft	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
extracellular exosome	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
glutamatergic synapse	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
calcium channel complex	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
extracellular space	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
endosome	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
focal adhesion	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
actin cytoskeleton	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
nucleus	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
nucleoplasm	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
cytoplasm	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
spindle	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
cytosol	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription factor TFIIH core complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription factor TFIID complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription factor TFIIH holo complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
CAK-ERCC2 complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
MMXD complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
nucleus	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
cytoplasm	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
nucleoplasm	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
cytoplasm	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
cytosol	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
ribosome	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
membrane	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
perinuclear region of cytoplasm	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
nucleus	Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)
PcG protein complex	Casein kinase II subunit alpha'	Homo sapiens (human)
acrosomal vesicle	Casein kinase II subunit alpha'	Homo sapiens (human)
nucleus	Casein kinase II subunit alpha'	Homo sapiens (human)
nucleoplasm	Casein kinase II subunit alpha'	Homo sapiens (human)
cytosol	Casein kinase II subunit alpha'	Homo sapiens (human)
protein kinase CK2 complex	Casein kinase II subunit alpha'	Homo sapiens (human)
chromatin	Casein kinase II subunit alpha'	Homo sapiens (human)
cytosol	Casein kinase II subunit alpha'	Homo sapiens (human)
nucleus	Casein kinase II subunit alpha'	Homo sapiens (human)
Golgi membrane	Ras-related protein Rab-6A	Homo sapiens (human)
acrosomal membrane	Ras-related protein Rab-6A	Homo sapiens (human)
endoplasmic reticulum membrane	Ras-related protein Rab-6A	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-6A	Homo sapiens (human)
trans-Golgi network	Ras-related protein Rab-6A	Homo sapiens (human)
cytosol	Ras-related protein Rab-6A	Homo sapiens (human)
plasma membrane	Ras-related protein Rab-6A	Homo sapiens (human)
membrane	Ras-related protein Rab-6A	Homo sapiens (human)
secretory granule membrane	Ras-related protein Rab-6A	Homo sapiens (human)
cytoplasmic vesicle	Ras-related protein Rab-6A	Homo sapiens (human)
trans-Golgi network membrane	Ras-related protein Rab-6A	Homo sapiens (human)
extracellular exosome	Ras-related protein Rab-6A	Homo sapiens (human)
endosome to plasma membrane transport vesicle	Ras-related protein Rab-6A	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-6A	Homo sapiens (human)
endomembrane system	Ras-related protein Rab-6A	Homo sapiens (human)
photoreceptor outer segment	Serine/threonine-protein kinase MAK	Homo sapiens (human)
photoreceptor inner segment	Serine/threonine-protein kinase MAK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase MAK	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase MAK	Homo sapiens (human)
axoneme	Serine/threonine-protein kinase MAK	Homo sapiens (human)
midbody	Serine/threonine-protein kinase MAK	Homo sapiens (human)
motile cilium	Serine/threonine-protein kinase MAK	Homo sapiens (human)
photoreceptor connecting cilium	Serine/threonine-protein kinase MAK	Homo sapiens (human)
mitotic spindle	Serine/threonine-protein kinase MAK	Homo sapiens (human)
cilium	Serine/threonine-protein kinase MAK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase MAK	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MAK	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 11B	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 11B	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 11B	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 1	Homo sapiens (human)
receptor complex	Ephrin type-A receptor 1	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 1	Homo sapiens (human)
collagen-containing extracellular matrix	Fibroblast growth factor receptor 2	Homo sapiens (human)
extracellular region	Fibroblast growth factor receptor 2	Homo sapiens (human)
nucleus	Fibroblast growth factor receptor 2	Homo sapiens (human)
cytoplasm	Fibroblast growth factor receptor 2	Homo sapiens (human)
Golgi apparatus	Fibroblast growth factor receptor 2	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 2	Homo sapiens (human)
cell cortex	Fibroblast growth factor receptor 2	Homo sapiens (human)
cell surface	Fibroblast growth factor receptor 2	Homo sapiens (human)
membrane	Fibroblast growth factor receptor 2	Homo sapiens (human)
cytoplasmic vesicle	Fibroblast growth factor receptor 2	Homo sapiens (human)
excitatory synapse	Fibroblast growth factor receptor 2	Homo sapiens (human)
receptor complex	Fibroblast growth factor receptor 2	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 2	Homo sapiens (human)
extracellular space	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
plasma membrane	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
basolateral plasma membrane	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
apical plasma membrane	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
lateral plasma membrane	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
ERBB3:ERBB2 complex	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
receptor complex	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
plasma membrane	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
basal plasma membrane	Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)
cytoplasm	Multifunctional protein ADE2	Homo sapiens (human)
cytosol	Multifunctional protein ADE2	Homo sapiens (human)
membrane	Multifunctional protein ADE2	Homo sapiens (human)
extracellular exosome	Multifunctional protein ADE2	Homo sapiens (human)
cell-cell junction	Fibroblast growth factor receptor 4	Homo sapiens (human)
extracellular region	Fibroblast growth factor receptor 4	Homo sapiens (human)
endosome	Fibroblast growth factor receptor 4	Homo sapiens (human)
endoplasmic reticulum	Fibroblast growth factor receptor 4	Homo sapiens (human)
Golgi apparatus	Fibroblast growth factor receptor 4	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 4	Homo sapiens (human)
transport vesicle	Fibroblast growth factor receptor 4	Homo sapiens (human)
receptor complex	Fibroblast growth factor receptor 4	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 4	Homo sapiens (human)
focal adhesion	Fibroblast growth factor receptor 3	Homo sapiens (human)
extracellular region	Fibroblast growth factor receptor 3	Homo sapiens (human)
endoplasmic reticulum	Fibroblast growth factor receptor 3	Homo sapiens (human)
Golgi apparatus	Fibroblast growth factor receptor 3	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 3	Homo sapiens (human)
cell surface	Fibroblast growth factor receptor 3	Homo sapiens (human)
transport vesicle	Fibroblast growth factor receptor 3	Homo sapiens (human)
receptor complex	Fibroblast growth factor receptor 3	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 3	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
centrosome	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
plasma membrane	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
extracellular exosome	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
basolateral plasma membrane	Carbonic anhydrase 4	Homo sapiens (human)
rough endoplasmic reticulum	Carbonic anhydrase 4	Homo sapiens (human)
endoplasmic reticulum-Golgi intermediate compartment	Carbonic anhydrase 4	Homo sapiens (human)
Golgi apparatus	Carbonic anhydrase 4	Homo sapiens (human)
trans-Golgi network	Carbonic anhydrase 4	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 4	Homo sapiens (human)
external side of plasma membrane	Carbonic anhydrase 4	Homo sapiens (human)
cell surface	Carbonic anhydrase 4	Homo sapiens (human)
membrane	Carbonic anhydrase 4	Homo sapiens (human)
apical plasma membrane	Carbonic anhydrase 4	Homo sapiens (human)
transport vesicle membrane	Carbonic anhydrase 4	Homo sapiens (human)
secretory granule membrane	Carbonic anhydrase 4	Homo sapiens (human)
brush border membrane	Carbonic anhydrase 4	Homo sapiens (human)
perinuclear region of cytoplasm	Carbonic anhydrase 4	Homo sapiens (human)
extracellular exosome	Carbonic anhydrase 4	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 4	Homo sapiens (human)
mitochondrial inner membrane	Ferrochelatase, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Ferrochelatase, mitochondrial	Homo sapiens (human)
mitochondrion	Ferrochelatase, mitochondrial	Homo sapiens (human)
extracellular region	Carbonic anhydrase 6	Homo sapiens (human)
extracellular space	Carbonic anhydrase 6	Homo sapiens (human)
cytosol	Carbonic anhydrase 6	Homo sapiens (human)
extracellular exosome	Carbonic anhydrase 6	Homo sapiens (human)
extracellular space	Carbonic anhydrase 6	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
mitochondrion	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
mitochondrial outer membrane	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cell surface	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
neuron projection	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
perinuclear region of cytoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
postsynapse	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
glutamatergic synapse	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase JAK1	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK1	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK1	Homo sapiens (human)
nucleus	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase JAK1	Homo sapiens (human)
endosome	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase JAK1	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoplasm	Protein kinase C eta type	Homo sapiens (human)
cytosol	Protein kinase C eta type	Homo sapiens (human)
plasma membrane	Protein kinase C eta type	Homo sapiens (human)
cell-cell junction	Protein kinase C eta type	Homo sapiens (human)
extracellular exosome	Protein kinase C eta type	Homo sapiens (human)
chromosome, telomeric region	Cyclin-dependent kinase 2	Homo sapiens (human)
condensed chromosome	Cyclin-dependent kinase 2	Homo sapiens (human)
X chromosome	Cyclin-dependent kinase 2	Homo sapiens (human)
Y chromosome	Cyclin-dependent kinase 2	Homo sapiens (human)
male germ cell nucleus	Cyclin-dependent kinase 2	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 2	Homo sapiens (human)
nuclear envelope	Cyclin-dependent kinase 2	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 2	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 2	Homo sapiens (human)
endosome	Cyclin-dependent kinase 2	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 2	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 2	Homo sapiens (human)
Cajal body	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin A1-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin A2-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin E1-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin E2-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 2	Homo sapiens (human)
transcription regulator complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 2	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 2	Homo sapiens (human)
cytoplasm	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
cytosol	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
plasma membrane	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
cilium	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
membrane	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
presynapse	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
postsynapse	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
P-body	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
nucleus	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasm	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytosol	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasmic stress granule	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
membrane	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
RISC complex	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasmic stress granule	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
P-body	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasm	Activin receptor type-2A	Homo sapiens (human)
plasma membrane	Activin receptor type-2A	Homo sapiens (human)
cell surface	Activin receptor type-2A	Homo sapiens (human)
inhibin-betaglycan-ActRII complex	Activin receptor type-2A	Homo sapiens (human)
receptor complex	Activin receptor type-2A	Homo sapiens (human)
plasma membrane	Activin receptor type-2A	Homo sapiens (human)
activin receptor complex	Activin receptor type-2A	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 3	Homo sapiens (human)
nuclear envelope	Mitogen-activated protein kinase 3	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 3	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 3	Homo sapiens (human)
early endosome	Mitogen-activated protein kinase 3	Homo sapiens (human)
late endosome	Mitogen-activated protein kinase 3	Homo sapiens (human)
endoplasmic reticulum lumen	Mitogen-activated protein kinase 3	Homo sapiens (human)
Golgi apparatus	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoskeleton	Mitogen-activated protein kinase 3	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 3	Homo sapiens (human)
caveola	Mitogen-activated protein kinase 3	Homo sapiens (human)
focal adhesion	Mitogen-activated protein kinase 3	Homo sapiens (human)
pseudopodium	Mitogen-activated protein kinase 3	Homo sapiens (human)
glutamatergic synapse	Mitogen-activated protein kinase 3	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
cytosol	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
plasma membrane	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
dendrite	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
extracellular exosome	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
plasma membrane	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
nucleoplasm	Deoxycytidine kinase	Homo sapiens (human)
cytosol	Deoxycytidine kinase	Homo sapiens (human)
mitochondrion	Deoxycytidine kinase	Homo sapiens (human)
cytoplasm	Deoxycytidine kinase	Homo sapiens (human)
extracellular region	Mitogen-activated protein kinase 1	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 1	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 1	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 1	Homo sapiens (human)
early endosome	Mitogen-activated protein kinase 1	Homo sapiens (human)
late endosome	Mitogen-activated protein kinase 1	Homo sapiens (human)
endoplasmic reticulum lumen	Mitogen-activated protein kinase 1	Homo sapiens (human)
Golgi apparatus	Mitogen-activated protein kinase 1	Homo sapiens (human)
centrosome	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytoskeleton	Mitogen-activated protein kinase 1	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 1	Homo sapiens (human)
caveola	Mitogen-activated protein kinase 1	Homo sapiens (human)
focal adhesion	Mitogen-activated protein kinase 1	Homo sapiens (human)
pseudopodium	Mitogen-activated protein kinase 1	Homo sapiens (human)
azurophil granule lumen	Mitogen-activated protein kinase 1	Homo sapiens (human)
synapse	Mitogen-activated protein kinase 1	Homo sapiens (human)
mitotic spindle	Mitogen-activated protein kinase 1	Homo sapiens (human)
ficolin-1-rich granule lumen	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 1	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 1	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
focal adhesion	Ephrin type-A receptor 2	Homo sapiens (human)
cell surface	Ephrin type-A receptor 2	Homo sapiens (human)
lamellipodium	Ephrin type-A receptor 2	Homo sapiens (human)
leading edge membrane	Ephrin type-A receptor 2	Homo sapiens (human)
lamellipodium membrane	Ephrin type-A receptor 2	Homo sapiens (human)
ruffle membrane	Ephrin type-A receptor 2	Homo sapiens (human)
tight junction	Ephrin type-A receptor 2	Homo sapiens (human)
receptor complex	Ephrin type-A receptor 2	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
extracellular region	Ephrin type-A receptor 3	Homo sapiens (human)
nucleoplasm	Ephrin type-A receptor 3	Homo sapiens (human)
early endosome	Ephrin type-A receptor 3	Homo sapiens (human)
cytosol	Ephrin type-A receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 3	Homo sapiens (human)
actin cytoskeleton	Ephrin type-A receptor 3	Homo sapiens (human)
nuclear membrane	Ephrin type-A receptor 3	Homo sapiens (human)
dendrite	Ephrin type-A receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 8	Homo sapiens (human)
early endosome membrane	Ephrin type-A receptor 8	Homo sapiens (human)
neuron projection	Ephrin type-A receptor 8	Homo sapiens (human)
dendrite	Ephrin type-A receptor 8	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 8	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 2	Homo sapiens (human)
nucleoplasm	Ephrin type-B receptor 2	Homo sapiens (human)
cytosol	Ephrin type-B receptor 2	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 2	Homo sapiens (human)
cell surface	Ephrin type-B receptor 2	Homo sapiens (human)
axon	Ephrin type-B receptor 2	Homo sapiens (human)
dendrite	Ephrin type-B receptor 2	Homo sapiens (human)
presynaptic membrane	Ephrin type-B receptor 2	Homo sapiens (human)
neuronal cell body	Ephrin type-B receptor 2	Homo sapiens (human)
dendritic spine	Ephrin type-B receptor 2	Homo sapiens (human)
postsynaptic membrane	Ephrin type-B receptor 2	Homo sapiens (human)
hippocampal mossy fiber to CA3 synapse	Ephrin type-B receptor 2	Homo sapiens (human)
postsynapse	Ephrin type-B receptor 2	Homo sapiens (human)
glutamatergic synapse	Ephrin type-B receptor 2	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 2	Homo sapiens (human)
dendrite	Ephrin type-B receptor 2	Homo sapiens (human)
plasma membrane	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
membrane	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
receptor complex	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
plasma membrane	Leukocyte tyrosine kinase receptor	Homo sapiens (human)
plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytoplasmic side of plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
extrinsic component of plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
nucleus	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytoplasm	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytosol	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytoskeleton	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-12 receptor complex	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
extracellular exosome	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-23 receptor complex	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytosol	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
nucleoplasm	UMP-CMP kinase	Homo sapiens (human)
nucleolus	UMP-CMP kinase	Homo sapiens (human)
cytosol	UMP-CMP kinase	Homo sapiens (human)
extracellular exosome	UMP-CMP kinase	Homo sapiens (human)
cytoplasm	UMP-CMP kinase	Homo sapiens (human)
nucleus	UMP-CMP kinase	Homo sapiens (human)
nucleus	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
cytosol	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
extracellular exosome	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
nucleus	Wee1-like protein kinase	Homo sapiens (human)
nucleoplasm	Wee1-like protein kinase	Homo sapiens (human)
nucleolus	Wee1-like protein kinase	Homo sapiens (human)
cytoplasm	Wee1-like protein kinase	Homo sapiens (human)
endoplasmic reticulum membrane	Heme oxygenase 2	Homo sapiens (human)
plasma membrane	Heme oxygenase 2	Homo sapiens (human)
membrane	Heme oxygenase 2	Homo sapiens (human)
specific granule membrane	Heme oxygenase 2	Homo sapiens (human)
extracellular space	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell surface	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
receptor complex	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 4	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 4	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 4	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 4	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 4	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 4	Homo sapiens (human)
cytosol	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
methionine adenosyltransferase complex	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
cytosol	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
nucleus	DnaJ homolog subfamily A member 1	Homo sapiens (human)
mitochondrion	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytosol	DnaJ homolog subfamily A member 1	Homo sapiens (human)
microtubule cytoskeleton	DnaJ homolog subfamily A member 1	Homo sapiens (human)
membrane	DnaJ homolog subfamily A member 1	Homo sapiens (human)
perinuclear region of cytoplasm	DnaJ homolog subfamily A member 1	Homo sapiens (human)
extracellular exosome	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytoplasmic side of endoplasmic reticulum membrane	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytoplasm	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytosol	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytoplasm	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
mitochondrial intermembrane space	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nucleus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
spindle	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cytosol	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell-cell junction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell cortex	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
microtubule cytoskeleton	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
lamellipodium	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
vesicle	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
ciliary basal body	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
postsynapse	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glutamatergic synapse	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein-containing complex	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nucleus	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
early endosome	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cytosol	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cell cortex	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
ruffle membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cytosol	G protein-coupled receptor kinase 4	Homo sapiens (human)
plasma membrane	G protein-coupled receptor kinase 4	Homo sapiens (human)
cell cortex	G protein-coupled receptor kinase 4	Homo sapiens (human)
photoreceptor disc membrane	G protein-coupled receptor kinase 4	Homo sapiens (human)
cytoplasm	G protein-coupled receptor kinase 4	Homo sapiens (human)
cytoplasm	Dual specificity protein kinase TTK	Homo sapiens (human)
spindle	Dual specificity protein kinase TTK	Homo sapiens (human)
membrane	Dual specificity protein kinase TTK	Homo sapiens (human)
kinetochore	Dual specificity protein kinase TTK	Homo sapiens (human)
nucleus	Dual specificity protein kinase TTK	Homo sapiens (human)
chromosome, telomeric region	DNA replication licensing factor MCM4	Homo sapiens (human)
nucleus	DNA replication licensing factor MCM4	Homo sapiens (human)
nucleoplasm	DNA replication licensing factor MCM4	Homo sapiens (human)
membrane	DNA replication licensing factor MCM4	Homo sapiens (human)
MCM complex	DNA replication licensing factor MCM4	Homo sapiens (human)
CMG complex	DNA replication licensing factor MCM4	Homo sapiens (human)
nucleus	DNA replication licensing factor MCM4	Homo sapiens (human)
mitochondrial matrix	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
mitochondrion	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
cytoplasm	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
mitochondrion	Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)
nuclear inner membrane	Prostaglandin G/H synthase 2	Homo sapiens (human)
nuclear outer membrane	Prostaglandin G/H synthase 2	Homo sapiens (human)
cytoplasm	Prostaglandin G/H synthase 2	Homo sapiens (human)
endoplasmic reticulum	Prostaglandin G/H synthase 2	Homo sapiens (human)
endoplasmic reticulum lumen	Prostaglandin G/H synthase 2	Homo sapiens (human)
endoplasmic reticulum membrane	Prostaglandin G/H synthase 2	Homo sapiens (human)
caveola	Prostaglandin G/H synthase 2	Homo sapiens (human)
neuron projection	Prostaglandin G/H synthase 2	Homo sapiens (human)
protein-containing complex	Prostaglandin G/H synthase 2	Homo sapiens (human)
neuron projection	Prostaglandin G/H synthase 2	Homo sapiens (human)
cytoplasm	Prostaglandin G/H synthase 2	Homo sapiens (human)
postsynaptic actin cytoskeleton	Myosin-10	Homo sapiens (human)
stress fiber	Myosin-10	Homo sapiens (human)
nucleus	Myosin-10	Homo sapiens (human)
cytoplasm	Myosin-10	Homo sapiens (human)
cytosol	Myosin-10	Homo sapiens (human)
cell cortex	Myosin-10	Homo sapiens (human)
lamellipodium	Myosin-10	Homo sapiens (human)
midbody	Myosin-10	Homo sapiens (human)
cleavage furrow	Myosin-10	Homo sapiens (human)
actomyosin	Myosin-10	Homo sapiens (human)
extracellular exosome	Myosin-10	Homo sapiens (human)
myosin II filament	Myosin-10	Homo sapiens (human)
myosin complex	Myosin-10	Homo sapiens (human)
myosin II complex	Myosin-10	Homo sapiens (human)
myosin filament	Myosin-10	Homo sapiens (human)
cytoplasm	Myosin-10	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
receptor complex	Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)
extracellular region	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
nucleoplasm	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
cytosol	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
extracellular region	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
nucleus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
early endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endoplasmic reticulum	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
Golgi apparatus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
external side of plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell junction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
membrane raft	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
anchoring junction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
sorting endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
extracellular region	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
nucleus	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
mitochondrion	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
early endosome	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
late endosome	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
peroxisomal membrane	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
endoplasmic reticulum	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
Golgi apparatus	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
microtubule	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
cell-cell junction	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
focal adhesion	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
cytoplasmic side of plasma membrane	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
perinuclear region of cytoplasm	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
endoplasmic reticulum	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
endoplasmic reticulum lumen	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
plasma membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
endosome membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
receptor complex	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
plasma membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
caveola	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
external side of plasma membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dendrite	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
neuronal cell body	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
HFE-transferrin receptor complex	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
receptor complex	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cytosol	Activin receptor type-1B	Homo sapiens (human)
plasma membrane	Activin receptor type-1B	Homo sapiens (human)
cell surface	Activin receptor type-1B	Homo sapiens (human)
receptor complex	Activin receptor type-1B	Homo sapiens (human)
activin receptor complex	Activin receptor type-1B	Homo sapiens (human)
plasma membrane	Activin receptor type-1B	Homo sapiens (human)
nucleus	TGF-beta receptor type-1	Homo sapiens (human)
endosome	TGF-beta receptor type-1	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-1	Homo sapiens (human)
bicellular tight junction	TGF-beta receptor type-1	Homo sapiens (human)
cell surface	TGF-beta receptor type-1	Homo sapiens (human)
membrane raft	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta ligand-receptor complex	TGF-beta receptor type-1	Homo sapiens (human)
receptor complex	TGF-beta receptor type-1	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-1	Homo sapiens (human)
activin receptor complex	TGF-beta receptor type-1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
cell surface	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
neuronal cell body	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
BMP receptor complex	Serine/threonine-protein kinase receptor R3	Homo sapiens (human)
extracellular region	TGF-beta receptor type-2	Homo sapiens (human)
cytosol	TGF-beta receptor type-2	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-2	Homo sapiens (human)
caveola	TGF-beta receptor type-2	Homo sapiens (human)
external side of plasma membrane	TGF-beta receptor type-2	Homo sapiens (human)
membrane	TGF-beta receptor type-2	Homo sapiens (human)
membrane raft	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta ligand-receptor complex	TGF-beta receptor type-2	Homo sapiens (human)
receptor complex	TGF-beta receptor type-2	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-2	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase CSK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase CSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase CSK	Homo sapiens (human)
cell-cell junction	Tyrosine-protein kinase CSK	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase CSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase CSK	Homo sapiens (human)
mitochondrial matrix	Glycine--tRNA ligase	Homo sapiens (human)
cytosol	Glycine--tRNA ligase	Homo sapiens (human)
secretory granule	Glycine--tRNA ligase	Homo sapiens (human)
axon	Glycine--tRNA ligase	Homo sapiens (human)
extracellular exosome	Glycine--tRNA ligase	Homo sapiens (human)
cytoplasm	Glycine--tRNA ligase	Homo sapiens (human)
mitochondrion	Glycine--tRNA ligase	Homo sapiens (human)
Golgi membrane	Protein kinase C iota type	Homo sapiens (human)
nucleus	Protein kinase C iota type	Homo sapiens (human)
nucleoplasm	Protein kinase C iota type	Homo sapiens (human)
endosome	Protein kinase C iota type	Homo sapiens (human)
cytosol	Protein kinase C iota type	Homo sapiens (human)
plasma membrane	Protein kinase C iota type	Homo sapiens (human)
brush border	Protein kinase C iota type	Homo sapiens (human)
bicellular tight junction	Protein kinase C iota type	Homo sapiens (human)
microtubule cytoskeleton	Protein kinase C iota type	Homo sapiens (human)
apical plasma membrane	Protein kinase C iota type	Homo sapiens (human)
cell leading edge	Protein kinase C iota type	Homo sapiens (human)
Schmidt-Lanterman incisure	Protein kinase C iota type	Homo sapiens (human)
intercellular bridge	Protein kinase C iota type	Homo sapiens (human)
extracellular exosome	Protein kinase C iota type	Homo sapiens (human)
tight junction	Protein kinase C iota type	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein kinase C iota type	Homo sapiens (human)
glutamatergic synapse	Protein kinase C iota type	Homo sapiens (human)
PAR polarity complex	Protein kinase C iota type	Homo sapiens (human)
nuclear exosome (RNase complex)	Exosome RNA helicase MTR4	Homo sapiens (human)
exosome (RNase complex)	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleus	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleoplasm	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleolus	Exosome RNA helicase MTR4	Homo sapiens (human)
nuclear speck	Exosome RNA helicase MTR4	Homo sapiens (human)
TRAMP complex	Exosome RNA helicase MTR4	Homo sapiens (human)
catalytic step 2 spliceosome	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleus	Exosome RNA helicase MTR4	Homo sapiens (human)
cytosol	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex, class IA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
intercalated disc	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
lamellipodium	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
perinuclear region of cytoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex, class IB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)
nucleus	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
nucleolus	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
cytosol	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex, class IA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
midbody	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
intracellular membrane-bounded organelle	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)
PML body	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
lysosomal membrane	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
Golgi membrane	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
mitochondrial outer membrane	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
lysosome	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
lysosomal membrane	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
endomembrane system	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
membrane	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
TORC1 complex	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
TORC2 complex	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
phagocytic vesicle	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
nuclear envelope	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase mTOR	Homo sapiens (human)
cytosol	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
plasma membrane	Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Tec	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase Tec	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Tec	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Tec	Homo sapiens (human)
nucleus	Tyrosine-protein kinase TXK	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase TXK	Homo sapiens (human)
nucleolus	Tyrosine-protein kinase TXK	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase TXK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase TXK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase TXK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase TXK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ABL2	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase ABL2	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ABL2	Homo sapiens (human)
extracellular region	Tyrosine-protein kinase FRK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase FRK	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase FRK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase FRK	Homo sapiens (human)
azurophil granule lumen	Tyrosine-protein kinase FRK	Homo sapiens (human)
specific granule lumen	Tyrosine-protein kinase FRK	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase FRK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase FRK	Homo sapiens (human)
cytosol	Carbonic anhydrase 7	Homo sapiens (human)
cytoplasm	Carbonic anhydrase 7	Homo sapiens (human)
plasma membrane	G protein-coupled receptor kinase 6	Homo sapiens (human)
membrane	G protein-coupled receptor kinase 6	Homo sapiens (human)
cytoplasm	G protein-coupled receptor kinase 6	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
immunological synapse	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cell-cell junction	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell receptor complex	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase SYK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase SYK	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase SYK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase SYK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase SYK	Homo sapiens (human)
early phagosome	Tyrosine-protein kinase SYK	Homo sapiens (human)
B cell receptor complex	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein-containing complex	Tyrosine-protein kinase SYK	Homo sapiens (human)
T cell receptor complex	Tyrosine-protein kinase SYK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase SYK	Homo sapiens (human)
proteasome complex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
nucleus	26S proteasome regulatory subunit 6B	Homo sapiens (human)
nucleoplasm	26S proteasome regulatory subunit 6B	Homo sapiens (human)
cytosol	26S proteasome regulatory subunit 6B	Homo sapiens (human)
membrane	26S proteasome regulatory subunit 6B	Homo sapiens (human)
inclusion body	26S proteasome regulatory subunit 6B	Homo sapiens (human)
synapse	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome accessory complex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
cytosolic proteasome complex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome regulatory particle, base subcomplex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 8	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 8	Homo sapiens (human)
axon	Mitogen-activated protein kinase 8	Homo sapiens (human)
synapse	Mitogen-activated protein kinase 8	Homo sapiens (human)
basal dendrite	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 9	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 9	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 9	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 9	Homo sapiens (human)
nuclear speck	Mitogen-activated protein kinase 9	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Mitogen-activated protein kinase 9	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 9	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 9	Homo sapiens (human)
nucleus	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
axon	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
dendrite cytoplasm	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
perikaryon	Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)
cytoplasm	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
nucleoplasm	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
membrane	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
photoreceptor outer segment	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
photoreceptor inner segment	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
lysosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
autophagosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
cytosol	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
mRNA cleavage and polyadenylation specificity factor complex	Casein kinase I isoform alpha	Homo sapiens (human)
keratin filament	Casein kinase I isoform alpha	Homo sapiens (human)
kinetochore	Casein kinase I isoform alpha	Homo sapiens (human)
centrosome	Casein kinase I isoform alpha	Homo sapiens (human)
spindle	Casein kinase I isoform alpha	Homo sapiens (human)
cytosol	Casein kinase I isoform alpha	Homo sapiens (human)
cilium	Casein kinase I isoform alpha	Homo sapiens (human)
membrane	Casein kinase I isoform alpha	Homo sapiens (human)
nuclear speck	Casein kinase I isoform alpha	Homo sapiens (human)
beta-catenin destruction complex	Casein kinase I isoform alpha	Homo sapiens (human)
ciliary basal body	Casein kinase I isoform alpha	Homo sapiens (human)
cytoplasm	Casein kinase I isoform alpha	Homo sapiens (human)
nucleus	Casein kinase I isoform alpha	Homo sapiens (human)
nucleus	Casein kinase I isoform delta	Homo sapiens (human)
nucleoplasm	Casein kinase I isoform delta	Homo sapiens (human)
Golgi apparatus	Casein kinase I isoform delta	Homo sapiens (human)
centrosome	Casein kinase I isoform delta	Homo sapiens (human)
spindle	Casein kinase I isoform delta	Homo sapiens (human)
cytosol	Casein kinase I isoform delta	Homo sapiens (human)
spindle microtubule	Casein kinase I isoform delta	Homo sapiens (human)
plasma membrane	Casein kinase I isoform delta	Homo sapiens (human)
endoplasmic reticulum-Golgi intermediate compartment membrane	Casein kinase I isoform delta	Homo sapiens (human)
ciliary basal body	Casein kinase I isoform delta	Homo sapiens (human)
perinuclear region of cytoplasm	Casein kinase I isoform delta	Homo sapiens (human)
nucleus	Casein kinase I isoform delta	Homo sapiens (human)
cytoplasm	Casein kinase I isoform delta	Homo sapiens (human)
spindle microtubule	Casein kinase I isoform delta	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
cytosol	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex, class IA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
phosphatidylinositol 3-kinase complex, class IB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)
nucleus	MAP kinase-activated protein kinase 2	Homo sapiens (human)
nucleoplasm	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cytoplasm	MAP kinase-activated protein kinase 2	Homo sapiens (human)
centrosome	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cytosol	MAP kinase-activated protein kinase 2	Homo sapiens (human)
extracellular exosome	MAP kinase-activated protein kinase 2	Homo sapiens (human)
nucleus	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cytoplasm	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 8	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 8	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 8	Homo sapiens (human)
nucleolus	Cyclin-dependent kinase 8	Homo sapiens (human)
CKM complex	Cyclin-dependent kinase 8	Homo sapiens (human)
ubiquitin ligase complex	Cyclin-dependent kinase 8	Homo sapiens (human)
mediator complex	Cyclin-dependent kinase 8	Homo sapiens (human)
protein-containing complex	Cyclin-dependent kinase 8	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 8	Homo sapiens (human)
mitochondrion	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrial outer membrane	Elongation factor Tu, mitochondrial	Homo sapiens (human)
membrane	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrial nucleoid	Elongation factor Tu, mitochondrial	Homo sapiens (human)
synapse	Elongation factor Tu, mitochondrial	Homo sapiens (human)
extracellular exosome	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrion	Elongation factor Tu, mitochondrial	Homo sapiens (human)
cytoplasm	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytosol	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytoplasm	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
nucleus	Casein kinase I isoform epsilon	Homo sapiens (human)
nucleoplasm	Casein kinase I isoform epsilon	Homo sapiens (human)
cytoplasm	Casein kinase I isoform epsilon	Homo sapiens (human)
cytosol	Casein kinase I isoform epsilon	Homo sapiens (human)
growth cone	Casein kinase I isoform epsilon	Homo sapiens (human)
neuronal cell body	Casein kinase I isoform epsilon	Homo sapiens (human)
ribonucleoprotein complex	Casein kinase I isoform epsilon	Homo sapiens (human)
cytoplasm	Casein kinase I isoform epsilon	Homo sapiens (human)
nucleus	Casein kinase I isoform epsilon	Homo sapiens (human)
nucleoplasm	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
nucleolus	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrion	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial membrane	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial nucleoid	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK1	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK2	Homo sapiens (human)
nucleoplasm	Dual specificity protein kinase CLK2	Homo sapiens (human)
nuclear body	Dual specificity protein kinase CLK2	Homo sapiens (human)
nuclear speck	Dual specificity protein kinase CLK2	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK2	Homo sapiens (human)
acrosomal vesicle	Dual specificity protein kinase CLK3	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK3	Homo sapiens (human)
nucleoplasm	Dual specificity protein kinase CLK3	Homo sapiens (human)
membrane	Dual specificity protein kinase CLK3	Homo sapiens (human)
nuclear speck	Dual specificity protein kinase CLK3	Homo sapiens (human)
intermediate filament cytoskeleton	Dual specificity protein kinase CLK3	Homo sapiens (human)
mitochondrion	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
beta-catenin destruction complex	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
neuronal cell body	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
apical dendrite	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
postsynapse	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
proximal dendrite	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cytoplasm	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
nucleus	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
axon	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
glutamatergic synapse	Glycogen synthase kinase-3 beta	Homo sapiens (human)
nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
nucleoplasm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytoplasm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
mitochondrion	Glycogen synthase kinase-3 beta	Homo sapiens (human)
centrosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 beta	Homo sapiens (human)
plasma membrane	Glycogen synthase kinase-3 beta	Homo sapiens (human)
axon	Glycogen synthase kinase-3 beta	Homo sapiens (human)
dendrite	Glycogen synthase kinase-3 beta	Homo sapiens (human)
beta-catenin destruction complex	Glycogen synthase kinase-3 beta	Homo sapiens (human)
presynapse	Glycogen synthase kinase-3 beta	Homo sapiens (human)
postsynapse	Glycogen synthase kinase-3 beta	Homo sapiens (human)
Wnt signalosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 beta	Homo sapiens (human)
axon	Glycogen synthase kinase-3 beta	Homo sapiens (human)
nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytoplasm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 7	Homo sapiens (human)
fibrillar center	Cyclin-dependent kinase 7	Homo sapiens (human)
male germ cell nucleus	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 7	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 7	Homo sapiens (human)
plasma membrane	Cyclin-dependent kinase 7	Homo sapiens (human)
perinuclear region of cytoplasm	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription factor TFIIH core complex	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription factor TFIIH holo complex	Cyclin-dependent kinase 7	Homo sapiens (human)
CAK-ERCC2 complex	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription factor TFIIK complex	Cyclin-dependent kinase 7	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 9	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 9	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 9	Homo sapiens (human)
cyclin/CDK positive transcription elongation factor complex	Cyclin-dependent kinase 9	Homo sapiens (human)
membrane	Cyclin-dependent kinase 9	Homo sapiens (human)
PML body	Cyclin-dependent kinase 9	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation factor complex	Cyclin-dependent kinase 9	Homo sapiens (human)
P-TEFb complex	Cyclin-dependent kinase 9	Homo sapiens (human)
photoreceptor outer segment	Ras-related protein Rab-27A	Homo sapiens (human)
extracellular region	Ras-related protein Rab-27A	Homo sapiens (human)
lysosome	Ras-related protein Rab-27A	Homo sapiens (human)
late endosome	Ras-related protein Rab-27A	Homo sapiens (human)
cytosol	Ras-related protein Rab-27A	Homo sapiens (human)
dendrite	Ras-related protein Rab-27A	Homo sapiens (human)
multivesicular body membrane	Ras-related protein Rab-27A	Homo sapiens (human)
Weibel-Palade body	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome membrane	Ras-related protein Rab-27A	Homo sapiens (human)
specific granule lumen	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome	Ras-related protein Rab-27A	Homo sapiens (human)
extracellular exosome	Ras-related protein Rab-27A	Homo sapiens (human)
exocytic vesicle	Ras-related protein Rab-27A	Homo sapiens (human)
exocytic vesicle	Ras-related protein Rab-27A	Homo sapiens (human)
apical plasma membrane	Ras-related protein Rab-27A	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-27A	Homo sapiens (human)
secretory granule	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome	Ras-related protein Rab-27A	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Blk	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Blk	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cell surface	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
nucleoplasm	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
lipid droplet	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cytosol	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
endosome membrane	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein-containing complex	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
early endosome	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
endoplasmic reticulum	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cytoplasm	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
lysosome	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
early endosome	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
late endosome	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
endoplasmic reticulum	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
voltage-gated potassium channel complex	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
basolateral plasma membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
apical plasma membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
transport vesicle	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
cytoplasmic vesicle membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
neuron projection	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
neuronal cell body	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane raft	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
ciliary base	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
lumenal side of membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
basolateral part of cell	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
monoatomic ion channel complex	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
membrane	Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
nucleolus	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
nucleoplasm	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
cytosol	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
plasma membrane	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
ruffle membrane	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
plasma membrane	Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
condensed nuclear chromosome	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
microtubule	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
midbody	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
axon	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
ciliary rootlet	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
ciliary transition zone	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
ciliary basal body	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
ciliary plasm	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek4	Homo sapiens (human)
extrinsic component of plasma membrane	Tyrosine-protein kinase JAK3	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK3	Homo sapiens (human)
endosome	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase JAK3	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK3	Homo sapiens (human)
cytoplasm	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
nucleoplasm	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cytoskeleton	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
spindle microtubule	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
synaptonemal complex	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centriole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
microtubule cytoskeleton	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
midbody	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle midzone	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic spindle pole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
chromatin	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
outer kinetochore	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
cytoplasm	Death-associated protein kinase 1	Homo sapiens (human)
plasma membrane	Death-associated protein kinase 1	Homo sapiens (human)
postsynaptic density	Death-associated protein kinase 1	Homo sapiens (human)
actin cytoskeleton	Death-associated protein kinase 1	Homo sapiens (human)
glutamatergic synapse	Death-associated protein kinase 1	Homo sapiens (human)
DAPK1-calmodulin complex	Death-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Death-associated protein kinase 1	Homo sapiens (human)
nucleus	Death-associated protein kinase 1	Homo sapiens (human)
postsynapse	LIM domain kinase 1	Homo sapiens (human)
glutamatergic synapse	LIM domain kinase 1	Homo sapiens (human)
male germ cell nucleus	LIM domain kinase 1	Homo sapiens (human)
cytoplasm	LIM domain kinase 1	Homo sapiens (human)
cytosol	LIM domain kinase 1	Homo sapiens (human)
cytoskeleton	LIM domain kinase 1	Homo sapiens (human)
focal adhesion	LIM domain kinase 1	Homo sapiens (human)
membrane	LIM domain kinase 1	Homo sapiens (human)
nuclear speck	LIM domain kinase 1	Homo sapiens (human)
lamellipodium	LIM domain kinase 1	Homo sapiens (human)
neuron projection	LIM domain kinase 1	Homo sapiens (human)
nucleus	LIM domain kinase 1	Homo sapiens (human)
neuron projection	LIM domain kinase 1	Homo sapiens (human)
cytoplasm	LIM domain kinase 1	Homo sapiens (human)
nucleus	LIM domain kinase 2	Homo sapiens (human)
cytoplasm	LIM domain kinase 2	Homo sapiens (human)
cis-Golgi network	LIM domain kinase 2	Homo sapiens (human)
centrosome	LIM domain kinase 2	Homo sapiens (human)
perinuclear region of cytoplasm	LIM domain kinase 2	Homo sapiens (human)
mitotic spindle	LIM domain kinase 2	Homo sapiens (human)
nucleus	LIM domain kinase 2	Homo sapiens (human)
cytoplasm	LIM domain kinase 2	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 12	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 12	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 12	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 12	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 12	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 10	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 10	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 10	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 10	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 10	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 10	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 10	Homo sapiens (human)
nucleus	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytoplasm	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytosol	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
extracellular space	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytosol	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
nuclear body	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
membrane	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
Golgi apparatus	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cytoplasmic stress granule	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
nuclear speck	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
axon	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
dendrite	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
neuronal cell body	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 3	Homo sapiens (human)
cytosol	Ephrin type-B receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 3	Homo sapiens (human)
dendrite	Ephrin type-B receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 3	Homo sapiens (human)
rough endoplasmic reticulum	Ephrin type-A receptor 5	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 5	Homo sapiens (human)
external side of plasma membrane	Ephrin type-A receptor 5	Homo sapiens (human)
axon	Ephrin type-A receptor 5	Homo sapiens (human)
dendrite	Ephrin type-A receptor 5	Homo sapiens (human)
neuronal cell body	Ephrin type-A receptor 5	Homo sapiens (human)
perinuclear region of cytoplasm	Ephrin type-A receptor 5	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 5	Homo sapiens (human)
dendrite	Ephrin type-A receptor 5	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 4	Homo sapiens (human)
cytosol	Ephrin type-B receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 4	Homo sapiens (human)
extracellular exosome	Ephrin type-B receptor 4	Homo sapiens (human)
receptor complex	Ephrin type-B receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 4	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 1	Homo sapiens (human)
endoplasmic reticulum	Ephrin type-B receptor 1	Homo sapiens (human)
cytosol	Ephrin type-B receptor 1	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 1	Homo sapiens (human)
axon	Ephrin type-B receptor 1	Homo sapiens (human)
early endosome membrane	Ephrin type-B receptor 1	Homo sapiens (human)
filopodium tip	Ephrin type-B receptor 1	Homo sapiens (human)
membrane raft	Ephrin type-B receptor 1	Homo sapiens (human)
extracellular exosome	Ephrin type-B receptor 1	Homo sapiens (human)
glutamatergic synapse	Ephrin type-B receptor 1	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 1	Homo sapiens (human)
dendrite	Ephrin type-B receptor 1	Homo sapiens (human)
cytoplasm	Ephrin type-A receptor 4	Homo sapiens (human)
mitochondrial outer membrane	Ephrin type-A receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 4	Homo sapiens (human)
adherens junction	Ephrin type-A receptor 4	Homo sapiens (human)
cell surface	Ephrin type-A receptor 4	Homo sapiens (human)
filopodium	Ephrin type-A receptor 4	Homo sapiens (human)
axon	Ephrin type-A receptor 4	Homo sapiens (human)
dendrite	Ephrin type-A receptor 4	Homo sapiens (human)
neuromuscular junction	Ephrin type-A receptor 4	Homo sapiens (human)
early endosome membrane	Ephrin type-A receptor 4	Homo sapiens (human)
presynaptic membrane	Ephrin type-A receptor 4	Homo sapiens (human)
dendritic spine	Ephrin type-A receptor 4	Homo sapiens (human)
dendritic shaft	Ephrin type-A receptor 4	Homo sapiens (human)
perikaryon	Ephrin type-A receptor 4	Homo sapiens (human)
axon terminus	Ephrin type-A receptor 4	Homo sapiens (human)
axonal growth cone	Ephrin type-A receptor 4	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Ephrin type-A receptor 4	Homo sapiens (human)
postsynaptic density membrane	Ephrin type-A receptor 4	Homo sapiens (human)
glutamatergic synapse	Ephrin type-A receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 4	Homo sapiens (human)
dendrite	Ephrin type-A receptor 4	Homo sapiens (human)
mitochondrial intermembrane space	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
extracellular exosome	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
sperm mitochondrial sheath	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
cytoplasm	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
mitochondrion	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
nucleoplasm	Adenosine kinase	Homo sapiens (human)
cytosol	Adenosine kinase	Homo sapiens (human)
plasma membrane	Adenosine kinase	Homo sapiens (human)
nucleus	Adenosine kinase	Homo sapiens (human)
cytosol	Adenosine kinase	Homo sapiens (human)
cytoplasm	Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK1	Homo sapiens (human)
cytoplasm	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
membrane	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
cytoplasm	Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)
virion membrane	Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus
exocyst	Ras-related protein Rab-10	Homo sapiens (human)
plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
Golgi membrane	Ras-related protein Rab-10	Homo sapiens (human)
endosome	Ras-related protein Rab-10	Homo sapiens (human)
endoplasmic reticulum membrane	Ras-related protein Rab-10	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-10	Homo sapiens (human)
trans-Golgi network	Ras-related protein Rab-10	Homo sapiens (human)
cytosol	Ras-related protein Rab-10	Homo sapiens (human)
cytoskeleton	Ras-related protein Rab-10	Homo sapiens (human)
plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
adherens junction	Ras-related protein Rab-10	Homo sapiens (human)
focal adhesion	Ras-related protein Rab-10	Homo sapiens (human)
cilium	Ras-related protein Rab-10	Homo sapiens (human)
endosome membrane	Ras-related protein Rab-10	Homo sapiens (human)
cytoplasmic vesicle membrane	Ras-related protein Rab-10	Homo sapiens (human)
secretory granule membrane	Ras-related protein Rab-10	Homo sapiens (human)
phagocytic vesicle membrane	Ras-related protein Rab-10	Homo sapiens (human)
insulin-responsive compartment	Ras-related protein Rab-10	Homo sapiens (human)
perinuclear region of cytoplasm	Ras-related protein Rab-10	Homo sapiens (human)
recycling endosome	Ras-related protein Rab-10	Homo sapiens (human)
recycling endosome membrane	Ras-related protein Rab-10	Homo sapiens (human)
extracellular exosome	Ras-related protein Rab-10	Homo sapiens (human)
exocytic vesicle	Ras-related protein Rab-10	Homo sapiens (human)
endoplasmic reticulum tubular network	Ras-related protein Rab-10	Homo sapiens (human)
recycling endosome	Ras-related protein Rab-10	Homo sapiens (human)
secretory vesicle	Ras-related protein Rab-10	Homo sapiens (human)
membrane	Ras-related protein Rab-10	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-10	Homo sapiens (human)
nucleus	Actin-related protein 3	Homo sapiens (human)
cytoplasm	Actin-related protein 3	Homo sapiens (human)
cytosol	Actin-related protein 3	Homo sapiens (human)
brush border	Actin-related protein 3	Homo sapiens (human)
cell-cell junction	Actin-related protein 3	Homo sapiens (human)
focal adhesion	Actin-related protein 3	Homo sapiens (human)
actin cytoskeleton	Actin-related protein 3	Homo sapiens (human)
membrane	Actin-related protein 3	Homo sapiens (human)
lamellipodium	Actin-related protein 3	Homo sapiens (human)
site of double-strand break	Actin-related protein 3	Homo sapiens (human)
extracellular exosome	Actin-related protein 3	Homo sapiens (human)
Arp2/3 protein complex	Actin-related protein 3	Homo sapiens (human)
extracellular region	Actin-related protein 2	Homo sapiens (human)
nucleus	Actin-related protein 2	Homo sapiens (human)
cytoplasm	Actin-related protein 2	Homo sapiens (human)
cytosol	Actin-related protein 2	Homo sapiens (human)
focal adhesion	Actin-related protein 2	Homo sapiens (human)
actin cytoskeleton	Actin-related protein 2	Homo sapiens (human)
membrane	Actin-related protein 2	Homo sapiens (human)
actin cap	Actin-related protein 2	Homo sapiens (human)
azurophil granule lumen	Actin-related protein 2	Homo sapiens (human)
site of double-strand break	Actin-related protein 2	Homo sapiens (human)
cell projection	Actin-related protein 2	Homo sapiens (human)
extracellular exosome	Actin-related protein 2	Homo sapiens (human)
ficolin-1-rich granule lumen	Actin-related protein 2	Homo sapiens (human)
Arp2/3 protein complex	Actin-related protein 2	Homo sapiens (human)
cell cortex	Actin-related protein 2	Homo sapiens (human)
Flemming body	GTP-binding nuclear protein Ran	Homo sapiens (human)
male germ cell nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
manchette	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
nuclear envelope	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleoplasm	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleolus	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytoplasm	GTP-binding nuclear protein Ran	Homo sapiens (human)
centriole	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytosol	GTP-binding nuclear protein Ran	Homo sapiens (human)
membrane	GTP-binding nuclear protein Ran	Homo sapiens (human)
midbody	GTP-binding nuclear protein Ran	Homo sapiens (human)
sperm flagellum	GTP-binding nuclear protein Ran	Homo sapiens (human)
melanosome	GTP-binding nuclear protein Ran	Homo sapiens (human)
recycling endosome	GTP-binding nuclear protein Ran	Homo sapiens (human)
extracellular exosome	GTP-binding nuclear protein Ran	Homo sapiens (human)
chromatin	GTP-binding nuclear protein Ran	Homo sapiens (human)
nuclear pore	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein-containing complex	GTP-binding nuclear protein Ran	Homo sapiens (human)
RNA nuclear export complex	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytoplasm	GTP-binding nuclear protein Ran	Homo sapiens (human)
actin filament	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
postsynapse	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
glutamatergic synapse	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
nucleus	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cytoplasm	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
endoplasmic reticulum membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
trans-Golgi network	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cytosol	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
plasma membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
focal adhesion	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cell cortex	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
lamellipodium	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
secretory granule membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
ruffle membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
melanosome	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
NADPH oxidase complex	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
dendritic spine	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
recycling endosome membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
extracellular exosome	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
ficolin-1-rich granule membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cytoplasmic vesicle	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
plasma membrane	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
dendritic spine	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
cytoskeleton	Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)
PcG protein complex	Casein kinase II subunit alpha	Homo sapiens (human)
PML body	Casein kinase II subunit alpha	Homo sapiens (human)
nucleus	Casein kinase II subunit alpha	Homo sapiens (human)
nucleoplasm	Casein kinase II subunit alpha	Homo sapiens (human)
cytosol	Casein kinase II subunit alpha	Homo sapiens (human)
plasma membrane	Casein kinase II subunit alpha	Homo sapiens (human)
protein kinase CK2 complex	Casein kinase II subunit alpha	Homo sapiens (human)
Sin3-type complex	Casein kinase II subunit alpha	Homo sapiens (human)
cytosol	Casein kinase II subunit alpha	Homo sapiens (human)
nucleus	Casein kinase II subunit alpha	Homo sapiens (human)
nucleus	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
autophagosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
endoplasmic reticulum membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
cytosol	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)
nucleus	SRSF protein kinase 2	Homo sapiens (human)
nucleoplasm	SRSF protein kinase 2	Homo sapiens (human)
nucleolus	SRSF protein kinase 2	Homo sapiens (human)
cytoplasm	SRSF protein kinase 2	Homo sapiens (human)
cytosol	SRSF protein kinase 2	Homo sapiens (human)
nuclear speck	SRSF protein kinase 2	Homo sapiens (human)
chromatin	SRSF protein kinase 2	Homo sapiens (human)
nucleus	SRSF protein kinase 2	Homo sapiens (human)
cytoplasm	SRSF protein kinase 2	Homo sapiens (human)
cytosol	Casein kinase I isoform gamma-2	Homo sapiens (human)
cell cortex	Casein kinase I isoform gamma-2	Homo sapiens (human)
membrane	Casein kinase I isoform gamma-2	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-2	Homo sapiens (human)
plasma membrane	Casein kinase I isoform gamma-2	Homo sapiens (human)
nucleus	Casein kinase I isoform gamma-2	Homo sapiens (human)
cellular_component	Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 3	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 3	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 3	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase-like 1	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase-like 1	Homo sapiens (human)
ciliary transition zone	Cyclin-dependent kinase-like 1	Homo sapiens (human)
intracellular membrane-bounded organelle	Cyclin-dependent kinase-like 1	Homo sapiens (human)
extracellular exosome	Cyclin-dependent kinase-like 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase-like 1	Homo sapiens (human)
ruffle	Cyclin-dependent kinase 6	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 6	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 6	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 6	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 6	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin D1-CDK6 complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin D3-CDK6 complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin D2-CDK6 complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 6	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 6	Homo sapiens (human)
microtubule	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent-like kinase 5	Homo sapiens (human)
nucleus	Cyclin-dependent-like kinase 5	Homo sapiens (human)
nucleoplasm	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cytoplasm	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cytosol	Cyclin-dependent-like kinase 5	Homo sapiens (human)
plasma membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
postsynaptic density	Cyclin-dependent-like kinase 5	Homo sapiens (human)
membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein kinase 5 complex	Cyclin-dependent-like kinase 5	Homo sapiens (human)
lamellipodium	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cell junction	Cyclin-dependent-like kinase 5	Homo sapiens (human)
filopodium	Cyclin-dependent-like kinase 5	Homo sapiens (human)
axon	Cyclin-dependent-like kinase 5	Homo sapiens (human)
dendrite	Cyclin-dependent-like kinase 5	Homo sapiens (human)
growth cone	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuromuscular junction	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron projection	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuronal cell body	Cyclin-dependent-like kinase 5	Homo sapiens (human)
perikaryon	Cyclin-dependent-like kinase 5	Homo sapiens (human)
presynapse	Cyclin-dependent-like kinase 5	Homo sapiens (human)
nucleus	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cytoplasm	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle	Cyclin-dependent kinase 16	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 16	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 16	Homo sapiens (human)
plasma membrane	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasmic side of plasma membrane	Cyclin-dependent kinase 16	Homo sapiens (human)
microtubule cytoskeleton	Cyclin-dependent kinase 16	Homo sapiens (human)
neuron projection	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 16	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 17	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 17	Homo sapiens (human)
plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
Z disc	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
L-type voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)
nucleus	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
cytoplasm	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
cytosol	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
membrane	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
extracellular exosome	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
membrane	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
6-phosphofructokinase complex	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
Golgi apparatus	Protein kinase C epsilon type	Homo sapiens (human)
nucleus	Protein kinase C epsilon type	Homo sapiens (human)
cytoplasm	Protein kinase C epsilon type	Homo sapiens (human)
mitochondrion	Protein kinase C epsilon type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C epsilon type	Homo sapiens (human)
cytosol	Protein kinase C epsilon type	Homo sapiens (human)
plasma membrane	Protein kinase C epsilon type	Homo sapiens (human)
intracellular membrane-bounded organelle	Protein kinase C epsilon type	Homo sapiens (human)
intermediate filament cytoskeleton	Protein kinase C epsilon type	Homo sapiens (human)
synapse	Protein kinase C epsilon type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C epsilon type	Homo sapiens (human)
cell periphery	Protein kinase C epsilon type	Homo sapiens (human)
nucleus	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
mitochondrion	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
early endosome	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
late endosome	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
endoplasmic reticulum	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
Golgi apparatus	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
centrosome	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
plasma membrane	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
focal adhesion	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
stress fiber	Angiopoietin-1 receptor	Homo sapiens (human)
actin filament	Angiopoietin-1 receptor	Homo sapiens (human)
extracellular region	Angiopoietin-1 receptor	Homo sapiens (human)
cytoplasm	Angiopoietin-1 receptor	Homo sapiens (human)
plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
microvillus	Angiopoietin-1 receptor	Homo sapiens (human)
cell-cell junction	Angiopoietin-1 receptor	Homo sapiens (human)
focal adhesion	Angiopoietin-1 receptor	Homo sapiens (human)
basal plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
cell surface	Angiopoietin-1 receptor	Homo sapiens (human)
basolateral plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
apical plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
centriolar satellite	Angiopoietin-1 receptor	Homo sapiens (human)
membrane raft	Angiopoietin-1 receptor	Homo sapiens (human)
plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
receptor complex	Angiopoietin-1 receptor	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)
nucleolus	DNA topoisomerase 2-beta	Homo sapiens (human)
heterochromatin	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleus	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleoplasm	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleolus	DNA topoisomerase 2-beta	Homo sapiens (human)
cytosol	DNA topoisomerase 2-beta	Homo sapiens (human)
ribonucleoprotein complex	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleus	DNA topoisomerase 2-beta	Homo sapiens (human)
immunological synapse	Protein kinase C theta type	Homo sapiens (human)
cytosol	Protein kinase C theta type	Homo sapiens (human)
plasma membrane	Protein kinase C theta type	Homo sapiens (human)
aggresome	Protein kinase C theta type	Homo sapiens (human)
centriolar satellite	Protein kinase C theta type	Homo sapiens (human)
plasma membrane	Activin receptor type-1	Homo sapiens (human)
apical part of cell	Activin receptor type-1	Homo sapiens (human)
activin receptor complex	Activin receptor type-1	Homo sapiens (human)
BMP receptor complex	Activin receptor type-1	Homo sapiens (human)
plasma membrane	Activin receptor type-1	Homo sapiens (human)
stress fiber	Macrophage-stimulating protein receptor	Homo sapiens (human)
vacuole	Macrophage-stimulating protein receptor	Homo sapiens (human)
plasma membrane	Macrophage-stimulating protein receptor	Homo sapiens (human)
cell surface	Macrophage-stimulating protein receptor	Homo sapiens (human)
receptor complex	Macrophage-stimulating protein receptor	Homo sapiens (human)
plasma membrane	Macrophage-stimulating protein receptor	Homo sapiens (human)
stress fiber	Focal adhesion kinase 1	Homo sapiens (human)
nucleus	Focal adhesion kinase 1	Homo sapiens (human)
cytoplasm	Focal adhesion kinase 1	Homo sapiens (human)
centrosome	Focal adhesion kinase 1	Homo sapiens (human)
cytosol	Focal adhesion kinase 1	Homo sapiens (human)
cytoskeleton	Focal adhesion kinase 1	Homo sapiens (human)
plasma membrane	Focal adhesion kinase 1	Homo sapiens (human)
focal adhesion	Focal adhesion kinase 1	Homo sapiens (human)
cell cortex	Focal adhesion kinase 1	Homo sapiens (human)
ciliary basal body	Focal adhesion kinase 1	Homo sapiens (human)
intracellular membrane-bounded organelle	Focal adhesion kinase 1	Homo sapiens (human)
perinuclear region of cytoplasm	Focal adhesion kinase 1	Homo sapiens (human)
plasma membrane	Focal adhesion kinase 1	Homo sapiens (human)
focal adhesion	Focal adhesion kinase 1	Homo sapiens (human)
dendritic spine	Focal adhesion kinase 1	Homo sapiens (human)
stress fiber	Protein kinase C zeta type	Homo sapiens (human)
nuclear envelope	Protein kinase C zeta type	Homo sapiens (human)
cytoplasm	Protein kinase C zeta type	Homo sapiens (human)
endosome	Protein kinase C zeta type	Homo sapiens (human)
microtubule organizing center	Protein kinase C zeta type	Homo sapiens (human)
cytosol	Protein kinase C zeta type	Homo sapiens (human)
plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
cell-cell junction	Protein kinase C zeta type	Homo sapiens (human)
bicellular tight junction	Protein kinase C zeta type	Homo sapiens (human)
postsynaptic density	Protein kinase C zeta type	Homo sapiens (human)
membrane	Protein kinase C zeta type	Homo sapiens (human)
apical plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
nuclear matrix	Protein kinase C zeta type	Homo sapiens (human)
cell junction	Protein kinase C zeta type	Homo sapiens (human)
cell leading edge	Protein kinase C zeta type	Homo sapiens (human)
vesicle	Protein kinase C zeta type	Homo sapiens (human)
myelin sheath abaxonal region	Protein kinase C zeta type	Homo sapiens (human)
axon hillock	Protein kinase C zeta type	Homo sapiens (human)
apical cortex	Protein kinase C zeta type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C zeta type	Homo sapiens (human)
extracellular exosome	Protein kinase C zeta type	Homo sapiens (human)
tight junction	Protein kinase C zeta type	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein kinase C zeta type	Homo sapiens (human)
glutamatergic synapse	Protein kinase C zeta type	Homo sapiens (human)
PAR polarity complex	Protein kinase C zeta type	Homo sapiens (human)
extracellular region	Protein kinase C delta type	Homo sapiens (human)
nucleus	Protein kinase C delta type	Homo sapiens (human)
nucleoplasm	Protein kinase C delta type	Homo sapiens (human)
cytoplasm	Protein kinase C delta type	Homo sapiens (human)
mitochondrion	Protein kinase C delta type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C delta type	Homo sapiens (human)
cytosol	Protein kinase C delta type	Homo sapiens (human)
plasma membrane	Protein kinase C delta type	Homo sapiens (human)
cell-cell junction	Protein kinase C delta type	Homo sapiens (human)
nuclear matrix	Protein kinase C delta type	Homo sapiens (human)
azurophil granule lumen	Protein kinase C delta type	Homo sapiens (human)
endolysosome	Protein kinase C delta type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C delta type	Homo sapiens (human)
extracellular exosome	Protein kinase C delta type	Homo sapiens (human)
nucleus	Tyrosine-protein kinase BTK	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase BTK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase BTK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase BTK	Homo sapiens (human)
cytoplasmic vesicle	Tyrosine-protein kinase BTK	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase BTK	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase BTK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase BTK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
nuclear envelope	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
endoplasmic reticulum membrane	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
cell surface	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
receptor complex	Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)
cellular_component	Cyclin-dependent kinase 18	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 18	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 18	Homo sapiens (human)
nucleus	Activated CDC42 kinase 1	Homo sapiens (human)
cytoplasm	Activated CDC42 kinase 1	Homo sapiens (human)
endosome	Activated CDC42 kinase 1	Homo sapiens (human)
cytosol	Activated CDC42 kinase 1	Homo sapiens (human)
plasma membrane	Activated CDC42 kinase 1	Homo sapiens (human)
clathrin-coated pit	Activated CDC42 kinase 1	Homo sapiens (human)
adherens junction	Activated CDC42 kinase 1	Homo sapiens (human)
membrane	Activated CDC42 kinase 1	Homo sapiens (human)
clathrin-coated vesicle	Activated CDC42 kinase 1	Homo sapiens (human)
cytoplasmic vesicle membrane	Activated CDC42 kinase 1	Homo sapiens (human)
intracellular membrane-bounded organelle	Activated CDC42 kinase 1	Homo sapiens (human)
perinuclear region of cytoplasm	Activated CDC42 kinase 1	Homo sapiens (human)
cytoophidium	Activated CDC42 kinase 1	Homo sapiens (human)
Grb2-EGFR complex	Activated CDC42 kinase 1	Homo sapiens (human)
plasma membrane	Activated CDC42 kinase 1	Homo sapiens (human)
extracellular space	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
plasma membrane	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
extracellular exosome	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
receptor complex	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
plasma membrane	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
nucleus	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
cell-cell junction	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)
nuclear outer membrane	Myotonin-protein kinase	Homo sapiens (human)
mitochondrial outer membrane	Myotonin-protein kinase	Homo sapiens (human)
endoplasmic reticulum membrane	Myotonin-protein kinase	Homo sapiens (human)
cytosol	Myotonin-protein kinase	Homo sapiens (human)
plasma membrane	Myotonin-protein kinase	Homo sapiens (human)
nuclear membrane	Myotonin-protein kinase	Homo sapiens (human)
sarcoplasmic reticulum membrane	Myotonin-protein kinase	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
cell surface	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
perinuclear region of cytoplasm	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel complex	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
inward rectifier potassium channel complex	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
Golgi membrane	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
basolateral plasma membrane	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
membrane	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
growth cone	Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)
photoreceptor outer segment	Tyrosine-protein kinase Mer	Homo sapiens (human)
extracellular space	Tyrosine-protein kinase Mer	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Mer	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Mer	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Mer	Homo sapiens (human)
receptor complex	Tyrosine-protein kinase Mer	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 4	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 4	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 4	Homo sapiens (human)
nuclear body	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase 4	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
apical plasma membrane	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nuclear speck	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
axon	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
dendrite	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
neuronal cell body	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
chromatin	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
ruffle	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
chromosome	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
actin filament	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
focal adhesion	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
intercalated disc	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
Z disc	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
axon	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
nuclear membrane	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
ruffle membrane	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 1	Homo sapiens (human)
spindle	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 7	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 7	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 7	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 7	Homo sapiens (human)
PML body	Mitogen-activated protein kinase 7	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 7	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 7	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
postsynaptic density	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
secretory granule	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
glutamatergic synapse	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 3	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase 3	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cytosol	cGMP-dependent protein kinase 2	Homo sapiens (human)
apical plasma membrane	cGMP-dependent protein kinase 2	Homo sapiens (human)
nuclear membrane	cGMP-dependent protein kinase 2	Homo sapiens (human)
cytosol	Integrin-linked protein kinase	Homo sapiens (human)
plasma membrane	Integrin-linked protein kinase	Homo sapiens (human)
focal adhesion	Integrin-linked protein kinase	Homo sapiens (human)
membrane	Integrin-linked protein kinase	Homo sapiens (human)
sarcomere	Integrin-linked protein kinase	Homo sapiens (human)
lamellipodium	Integrin-linked protein kinase	Homo sapiens (human)
focal adhesion	Integrin-linked protein kinase	Homo sapiens (human)
stress fiber	Integrin-linked protein kinase	Homo sapiens (human)
Golgi membrane	Rho-associated protein kinase 1	Homo sapiens (human)
ruffle	Rho-associated protein kinase 1	Homo sapiens (human)
extracellular region	Rho-associated protein kinase 1	Homo sapiens (human)
centriole	Rho-associated protein kinase 1	Homo sapiens (human)
cytosol	Rho-associated protein kinase 1	Homo sapiens (human)
cytoskeleton	Rho-associated protein kinase 1	Homo sapiens (human)
plasma membrane	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasmic stress granule	Rho-associated protein kinase 1	Homo sapiens (human)
lamellipodium	Rho-associated protein kinase 1	Homo sapiens (human)
bleb	Rho-associated protein kinase 1	Homo sapiens (human)
secretory granule lumen	Rho-associated protein kinase 1	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Rho-associated protein kinase 1	Homo sapiens (human)
cytoskeleton	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasmic stress granule	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
membrane	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
plasma membrane	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
nuclear speck	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
catalytic step 2 spliceosome	Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)
mitochondrion	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
cytosol	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
plasma membrane	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
endosome membrane	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
death-inducing signaling complex	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
protein-containing complex	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
receptor complex	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
ripoptosome	Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
centrosome	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
endocytic vesicle membrane	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
sarcoplasmic reticulum membrane	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
synapse	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
membrane	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
endocytic vesicle membrane	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
sarcoplasmic reticulum membrane	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
membrane	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
endocytic vesicle membrane	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
sarcoplasmic reticulum membrane	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
sarcolemma	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytoskeleton	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nucleoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
cytoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nuclear speck	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
axon	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
dendrite	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
ribonucleoprotein complex	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
cytoplasm	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
sarcoplasmic reticulum	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
T-tubule	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
I band	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
L-type voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)
cytoplasm	Activin receptor type-2B	Homo sapiens (human)
plasma membrane	Activin receptor type-2B	Homo sapiens (human)
protein-containing complex	Activin receptor type-2B	Homo sapiens (human)
receptor complex	Activin receptor type-2B	Homo sapiens (human)
activin receptor complex	Activin receptor type-2B	Homo sapiens (human)
plasma membrane	Activin receptor type-2B	Homo sapiens (human)
caveola	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
extracellular space	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
nucleoplasm	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
clathrin-coated pit	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
adherens junction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
basal plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cell surface	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
postsynaptic density	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
apical plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
axon	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
dendrite	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
neuronal cell body	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
receptor complex	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
ruffle	Protein-tyrosine kinase 6	Homo sapiens (human)
nucleus	Protein-tyrosine kinase 6	Homo sapiens (human)
nucleoplasm	Protein-tyrosine kinase 6	Homo sapiens (human)
cytoplasm	Protein-tyrosine kinase 6	Homo sapiens (human)
cytosol	Protein-tyrosine kinase 6	Homo sapiens (human)
plasma membrane	Protein-tyrosine kinase 6	Homo sapiens (human)
nuclear body	Protein-tyrosine kinase 6	Homo sapiens (human)
plasma membrane	Protein-tyrosine kinase 6	Homo sapiens (human)
cytoplasm	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
plasma membrane	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
postsynaptic density	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
membrane	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
Z disc	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
dendrite	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
perikaryon	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
postsynaptic density membrane	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
L-type voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
voltage-gated calcium channel complex	Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)
acrosomal vesicle	cGMP-dependent protein kinase 1	Homo sapiens (human)
nucleoplasm	cGMP-dependent protein kinase 1	Homo sapiens (human)
cytoplasm	cGMP-dependent protein kinase 1	Homo sapiens (human)
Golgi apparatus	cGMP-dependent protein kinase 1	Homo sapiens (human)
cytosol	cGMP-dependent protein kinase 1	Homo sapiens (human)
plasma membrane	cGMP-dependent protein kinase 1	Homo sapiens (human)
sarcolemma	cGMP-dependent protein kinase 1	Homo sapiens (human)
cyclin K-CDK13 complex	Cyclin-dependent kinase 13	Homo sapiens (human)
extracellular region	Cyclin-dependent kinase 13	Homo sapiens (human)
extracellular space	Cyclin-dependent kinase 13	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 13	Homo sapiens (human)
Golgi apparatus	Cyclin-dependent kinase 13	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 13	Homo sapiens (human)
nuclear speck	Cyclin-dependent kinase 13	Homo sapiens (human)
ficolin-1-rich granule lumen	Cyclin-dependent kinase 13	Homo sapiens (human)
nuclear cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 13	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 13	Homo sapiens (human)
cyclin/CDK positive transcription elongation factor complex	Cyclin-dependent kinase 13	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
intracellular anatomical structure	Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
nucleus	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
nucleoplasm	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
cytosol	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
PML body	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
mitochondrial membrane	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
serine/threonine protein kinase complex	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
NMDA selective glutamate receptor complex	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
nucleus	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cytoplasm	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cytosol	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cytoskeleton	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
focal adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cell cortex	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
postsynaptic density	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
lamellipodium	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
dendrite	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
growth cone	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
neuronal cell body	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cell body	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
perinuclear region of cytoplasm	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
apical dendrite	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
presynapse	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
glutamatergic synapse	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
postsynaptic density, intracellular component	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
dendritic spine	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
focal adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
plasma membrane	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
caveola	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
nucleoplasm	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
nucleolus	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
endoplasmic reticulum	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
plasma membrane	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
caveola	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
cell surface	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
intercalated disc	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
membrane	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
lateral plasma membrane	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
Z disc	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
T-tubule	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
sarcolemma	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
perinuclear region of cytoplasm	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
voltage-gated sodium channel complex	Sodium channel protein type 5 subunit alpha	Homo sapiens (human)
plasma membrane	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
cell cortex	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
membrane	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
cytoplasm	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
chromosome, centromeric region	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
kinetochore	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
condensed nuclear chromosome	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleus	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleoplasm	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
chromosome	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
cytosol	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nuclear matrix	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic cohesin complex	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
meiotic cohesin complex	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic spindle pole	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
cohesin complex	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleus	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
chromosome, telomeric region	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
nucleus	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
nucleoplasm	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
cytoplasm	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
centrosome	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
membrane	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
NuRD complex	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
site of DNA damage	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
cerebellar granule cell to Purkinje cell synapse	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
chromatin	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
protein-containing complex	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
RNA polymerase II transcription regulator complex	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
nucleus	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
autophagosome membrane	Serine/threonine-protein kinase D1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase D1	Homo sapiens (human)
trans-Golgi network	Serine/threonine-protein kinase D1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D1	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase D1	Homo sapiens (human)
cell cortex	Serine/threonine-protein kinase D1	Homo sapiens (human)
Z disc	Serine/threonine-protein kinase D1	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase D1	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase D1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D1	Homo sapiens (human)
site of double-strand break	Serine/threonine-protein kinase 38	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 38	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 38	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 38	Homo sapiens (human)
glutamatergic synapse	Serine/threonine-protein kinase 38	Homo sapiens (human)
plasma membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
extracellular region	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
nucleus	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
nucleoplasm	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
mitochondrion	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
mitochondrial matrix	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
cytosol	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
plasma membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
basolateral plasma membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
neuromuscular junction	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
presynaptic membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
postsynaptic membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
postsynaptic density membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
glutamatergic synapse	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
GABA-ergic synapse	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
receptor complex	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
basal plasma membrane	Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)
nucleus	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 7	Homo sapiens (human)
glutamatergic synapse	Ephrin type-A receptor 7	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 7	Homo sapiens (human)
dendrite	Ephrin type-A receptor 7	Homo sapiens (human)
Golgi membrane	Delta(24)-sterol reductase	Homo sapiens (human)
nucleus	Delta(24)-sterol reductase	Homo sapiens (human)
endoplasmic reticulum	Delta(24)-sterol reductase	Homo sapiens (human)
endoplasmic reticulum membrane	Delta(24)-sterol reductase	Homo sapiens (human)
membrane	Delta(24)-sterol reductase	Homo sapiens (human)
cytoplasm	Delta(24)-sterol reductase	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cytoplasmic vesicle	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
cytoplasm	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
centrosome	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
cytosol	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
lamellipodium	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
perinuclear region of cytoplasm	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
cytoplasm	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
nucleus	Dual specificity testis-specific protein kinase 1	Homo sapiens (human)
stress fiber	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cytoplasm	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cytosol	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
plasma membrane	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
actin cytoskeleton	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
lamellipodium	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cleavage furrow	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cleavage furrow	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
stress fiber	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
lamellipodium	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cytoplasm	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 11	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 11	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 11	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 11	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase STK11	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase STK11	Homo sapiens (human)
membrane	Serine/threonine-protein kinase STK11	Homo sapiens (human)
Z disc	Serine/threonine-protein kinase STK11	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase STK11	Homo sapiens (human)
serine/threonine protein kinase complex	Serine/threonine-protein kinase STK11	Homo sapiens (human)
intracellular protein-containing complex	Serine/threonine-protein kinase STK11	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase STK11	Homo sapiens (human)
photoreceptor disc membrane	Rhodopsin kinase GRK1	Homo sapiens (human)
cytoplasm	Rhodopsin kinase GRK1	Homo sapiens (human)
plasma membrane	NT-3 growth factor receptor	Homo sapiens (human)
receptor complex	NT-3 growth factor receptor	Homo sapiens (human)
plasma membrane	NT-3 growth factor receptor	Homo sapiens (human)
axon	NT-3 growth factor receptor	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase N1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase N1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase N1	Homo sapiens (human)
endosome	Serine/threonine-protein kinase N1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase N1	Homo sapiens (human)
midbody	Serine/threonine-protein kinase N1	Homo sapiens (human)
cleavage furrow	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase N1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase N2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase N2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase N2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase N2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase N2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase N2	Homo sapiens (human)
nuclear body	Serine/threonine-protein kinase N2	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase N2	Homo sapiens (human)
midbody	Serine/threonine-protein kinase N2	Homo sapiens (human)
cleavage furrow	Serine/threonine-protein kinase N2	Homo sapiens (human)
apical junction complex	Serine/threonine-protein kinase N2	Homo sapiens (human)
intermediate filament cytoskeleton	Serine/threonine-protein kinase N2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase N2	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 14	Homo sapiens (human)
spindle pole	Mitogen-activated protein kinase 14	Homo sapiens (human)
extracellular region	Mitogen-activated protein kinase 14	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 14	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 14	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 14	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 14	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 14	Homo sapiens (human)
nuclear speck	Mitogen-activated protein kinase 14	Homo sapiens (human)
secretory granule lumen	Mitogen-activated protein kinase 14	Homo sapiens (human)
glutamatergic synapse	Mitogen-activated protein kinase 14	Homo sapiens (human)
ficolin-1-rich granule lumen	Mitogen-activated protein kinase 14	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 14	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 14	Homo sapiens (human)
fibrillar center	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
extracellular exosome	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
centrosome	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
microtubule	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
membrane	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
centrosome	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
early endosome	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
cytosol	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
plasma membrane	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
postsynaptic density	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
axon	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
dendrite	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
early endosome membrane	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
terminal bouton	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
perinuclear region of cytoplasm	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
receptor complex	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
axon terminus	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
plasma membrane	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
postsynaptic density	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
axon	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
dendritic spine	BDNF/NT-3 growth factors receptor	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 6	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 6	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 6	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 6	Homo sapiens (human)
septin cytoskeleton	Mitogen-activated protein kinase 6	Homo sapiens (human)
protein-containing complex	Mitogen-activated protein kinase 6	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 6	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 6	Homo sapiens (human)
nucleolus	Carbonic anhydrase 9	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 9	Homo sapiens (human)
membrane	Carbonic anhydrase 9	Homo sapiens (human)
basolateral plasma membrane	Carbonic anhydrase 9	Homo sapiens (human)
microvillus membrane	Carbonic anhydrase 9	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 9	Homo sapiens (human)
cytosol	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
phosphorylase kinase complex	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)
plasma membrane	Discoidin domain-containing receptor 2	Homo sapiens (human)
focal adhesion	Discoidin domain-containing receptor 2	Homo sapiens (human)
actin cytoskeleton	Discoidin domain-containing receptor 2	Homo sapiens (human)
apical plasma membrane	Discoidin domain-containing receptor 2	Homo sapiens (human)
receptor complex	Discoidin domain-containing receptor 2	Homo sapiens (human)
plasma membrane	Discoidin domain-containing receptor 2	Homo sapiens (human)
cytosol	AP2-associated protein kinase 1	Homo sapiens (human)
plasma membrane	AP2-associated protein kinase 1	Homo sapiens (human)
clathrin-coated pit	AP2-associated protein kinase 1	Homo sapiens (human)
clathrin-coated vesicle	AP2-associated protein kinase 1	Homo sapiens (human)
cell leading edge	AP2-associated protein kinase 1	Homo sapiens (human)
terminal bouton	AP2-associated protein kinase 1	Homo sapiens (human)
intracellular membrane-bounded organelle	AP2-associated protein kinase 1	Homo sapiens (human)
presynapse	AP2-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Myosin light chain kinase 3	Homo sapiens (human)
cytosol	Myosin light chain kinase 3	Homo sapiens (human)
cytoplasm	Myosin light chain kinase 3	Homo sapiens (human)
actin cytoskeleton	Myosin light chain kinase 3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SBK1	Homo sapiens (human)
extracellular exosome	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
perinuclear region of cytoplasm	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein-containing complex	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
plasma membrane	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
cytosol	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)
endomembrane system	Rab-like protein 3	Homo sapiens (human)
Golgi membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
extracellular space	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cytoplasm	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrion	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrial outer membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrial inner membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrial matrix	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
lysosome	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
endosome	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
endoplasmic reticulum	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
endoplasmic reticulum membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
Golgi apparatus	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
Golgi-associated vesicle	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
trans-Golgi network	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cytosol	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cytoskeleton	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
plasma membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
microvillus	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
axon	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
dendrite	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
growth cone	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
synaptic vesicle membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cytoplasmic vesicle	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
mitochondrial membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cytoplasmic side of mitochondrial outer membrane	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
dendrite cytoplasm	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
neuron projection	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
neuronal cell body	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
terminal bouton	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
perikaryon	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
intracellular membrane-bounded organelle	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
amphisome	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
autolysosome	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
extracellular exosome	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
endoplasmic reticulum exit site	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
multivesicular body, internal vesicle	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
postsynapse	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
glutamatergic synapse	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
caveola neck	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
presynaptic cytosol	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
ribonucleoprotein complex	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
Wnt signalosome	Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cell leading edge	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
cell leading edge	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
mitochondrion	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
mitochondrial matrix	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
cytoplasm	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase N3	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase N3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase N3	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase N3	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
ciliary tip	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytoplasm	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
basolateral plasma membrane	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
apical plasma membrane	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
anchoring junction	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
cytoplasm	Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)
nucleus	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mitochondrial inner membrane	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
peroxisome	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mitochondrial membrane	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mitochondrion	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
cytoplasm	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
endoplasmic reticulum	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
endoplasmic reticulum quality control compartment	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
IRE1-TRAF2-ASK1 complex	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
actin filament	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
membrane	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
lateral plasma membrane	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
microtubule bundle	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
mitochondrion	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
ribonucleoprotein granule	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
mitochondrial nucleoid	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
intracellular anatomical structure	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
microtubule cytoskeleton	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
nucleus	STE20-related kinase adapter protein alpha	Homo sapiens (human)
nucleoplasm	STE20-related kinase adapter protein alpha	Homo sapiens (human)
cytoplasm	STE20-related kinase adapter protein alpha	Homo sapiens (human)
cytosol	STE20-related kinase adapter protein alpha	Homo sapiens (human)
serine/threonine protein kinase complex	STE20-related kinase adapter protein alpha	Homo sapiens (human)
intracellular protein-containing complex	STE20-related kinase adapter protein alpha	Homo sapiens (human)
stress fiber	Myosin-14	Homo sapiens (human)
cytosol	Myosin-14	Homo sapiens (human)
brush border	Myosin-14	Homo sapiens (human)
membrane	Myosin-14	Homo sapiens (human)
growth cone	Myosin-14	Homo sapiens (human)
actomyosin	Myosin-14	Homo sapiens (human)
extracellular exosome	Myosin-14	Homo sapiens (human)
myosin II filament	Myosin-14	Homo sapiens (human)
myosin II complex	Myosin-14	Homo sapiens (human)
cytoplasm	Myosin-14	Homo sapiens (human)
myosin filament	Myosin-14	Homo sapiens (human)
mitochondrion	AarF domain-containing protein kinase 1	Homo sapiens (human)
mitochondrial inner membrane	AarF domain-containing protein kinase 1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
intermediate filament	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase pim-3	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
nuclear envelope	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
endoplasmic reticulum	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
mitochondrial membrane	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase VRK2	Homo sapiens (human)
nucleus	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
nucleoplasm	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
cytoplasm	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
centrosome	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
cytosol	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
nuclear speck	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
cytoplasm	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
PML body	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
nucleus	Homeodomain-interacting protein kinase 1	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
intracellular anatomical structure	Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase-like 3	Homo sapiens (human)
nucleus	Cyclin-dependent kinase-like 3	Homo sapiens (human)
nucleoplasm	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cytosol	MAP kinase-activated protein kinase 5	Homo sapiens (human)
septin cytoskeleton	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein-containing complex	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cytoplasm	MAP kinase-activated protein kinase 5	Homo sapiens (human)
nucleus	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
endoplasmic reticulum	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
distal axon	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase BRSK2	Homo sapiens (human)
cytoplasmic vesicle membrane	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK2	Homo sapiens (human)
cytoplasm	Misshapen-like kinase 1	Homo sapiens (human)
Golgi apparatus	Misshapen-like kinase 1	Homo sapiens (human)
cytosol	Misshapen-like kinase 1	Homo sapiens (human)
postsynaptic density	Misshapen-like kinase 1	Homo sapiens (human)
axon	Misshapen-like kinase 1	Homo sapiens (human)
dendrite	Misshapen-like kinase 1	Homo sapiens (human)
extracellular exosome	Misshapen-like kinase 1	Homo sapiens (human)
cytoplasm	Misshapen-like kinase 1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase DCLK2	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)
cytosol	Casein kinase I isoform alpha-like	Homo sapiens (human)
nucleus	Casein kinase I isoform alpha-like	Homo sapiens (human)
cytoplasm	Casein kinase I isoform alpha-like	Homo sapiens (human)
extracellular region	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
extracellular space	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
cytoplasm	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
lysosome	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
lysosomal membrane	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
early endosome	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
late endosome	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
endoplasmic reticulum	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
endoplasmic reticulum lumen	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
Golgi apparatus	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
plasma membrane	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
cell surface	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
COPII-coated ER to Golgi transport vesicle	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
extrinsic component of external side of plasma membrane	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
endolysosome membrane	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
perinuclear region of cytoplasm	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
PCSK9-AnxA2 complex	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
PCSK9-LDLR complex	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
extracellular space	Proprotein convertase subtilisin/kexin type 9	Homo sapiens (human)
nucleus	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
cytoplasm	Homeodomain-interacting protein kinase 4	Homo sapiens (human)
cytoplasm	Myosin-IIIa	Homo sapiens (human)
filopodium	Myosin-IIIa	Homo sapiens (human)
stereocilium tip	Myosin-IIIa	Homo sapiens (human)
filopodium tip	Myosin-IIIa	Homo sapiens (human)
myosin complex	Myosin-IIIa	Homo sapiens (human)
filamentous actin	Myosin-IIIa	Homo sapiens (human)
photoreceptor inner segment	Myosin-IIIa	Homo sapiens (human)
stereocilium tip	Myosin-IIIa	Homo sapiens (human)
filopodium tip	Myosin-IIIa	Homo sapiens (human)
nucleus	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
cell projection	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
cytoplasm	Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek11	Homo sapiens (human)
mitochondrion	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
membrane	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
autophagosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
endoplasmic reticulum	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
cytosol	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
intracellular organelle	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
extracellular exosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
axoneme	Mitogen-activated protein kinase 15	Homo sapiens (human)
extracellular region	Mitogen-activated protein kinase 15	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 15	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 15	Homo sapiens (human)
autophagosome	Mitogen-activated protein kinase 15	Homo sapiens (human)
Golgi apparatus	Mitogen-activated protein kinase 15	Homo sapiens (human)
centriole	Mitogen-activated protein kinase 15	Homo sapiens (human)
cell-cell junction	Mitogen-activated protein kinase 15	Homo sapiens (human)
bicellular tight junction	Mitogen-activated protein kinase 15	Homo sapiens (human)
cytoplasmic vesicle	Mitogen-activated protein kinase 15	Homo sapiens (human)
ciliary basal body	Mitogen-activated protein kinase 15	Homo sapiens (human)
meiotic spindle	Mitogen-activated protein kinase 15	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 15	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 15	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
synaptic vesicle	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
cell junction	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
presynaptic active zone	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
distal axon	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase BRSK1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 35	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase 35	Homo sapiens (human)
nuclear body	Serine/threonine-protein kinase 35	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 35	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 35	Homo sapiens (human)
microtubule organizing center	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
microtubule	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
photoreceptor disc membrane	Rhodopsin kinase GRK7	Homo sapiens (human)
cytoplasm	Rhodopsin kinase GRK7	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 32A	Homo sapiens (human)
cytoplasm	Myosin-IIIb	Homo sapiens (human)
stereocilium tip	Myosin-IIIb	Homo sapiens (human)
myosin complex	Myosin-IIIb	Homo sapiens (human)
stereocilium tip	Myosin-IIIb	Homo sapiens (human)
filopodium tip	Myosin-IIIb	Homo sapiens (human)
photoreceptor inner segment	Myosin-IIIb	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nucleoplasm	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
mitochondrion	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cytoplasmic stress granule	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
membrane	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cleavage body	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
tRNA-splicing ligase complex	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
ribonucleoprotein complex	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
nucleoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
cytoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
cytosol	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
ubiquitin ligase complex	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
ribonucleoprotein complex	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
cytoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
cytoskeleton	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase-like 2	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase-like 2	Homo sapiens (human)
centrosome	Cyclin-dependent kinase-like 2	Homo sapiens (human)
nucleus	Cyclin-dependent kinase-like 2	Homo sapiens (human)
membrane	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
early endosome	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
recycling endosome	Serine/threonine-protein kinase Sgk3	Homo sapiens (human)
mitochondrion	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
cytosol	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
plasma membrane	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
mitochondrial membrane	Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)
kinetochore	Aurora kinase B	Homo sapiens (human)
condensed chromosome, centromeric region	Aurora kinase B	Homo sapiens (human)
nucleus	Aurora kinase B	Homo sapiens (human)
nucleoplasm	Aurora kinase B	Homo sapiens (human)
spindle	Aurora kinase B	Homo sapiens (human)
cytosol	Aurora kinase B	Homo sapiens (human)
chromocenter	Aurora kinase B	Homo sapiens (human)
microtubule cytoskeleton	Aurora kinase B	Homo sapiens (human)
midbody	Aurora kinase B	Homo sapiens (human)
chromosome passenger complex	Aurora kinase B	Homo sapiens (human)
mitotic spindle pole	Aurora kinase B	Homo sapiens (human)
mitotic spindle midzone	Aurora kinase B	Homo sapiens (human)
kinetochore	Aurora kinase B	Homo sapiens (human)
spindle pole centrosome	Aurora kinase B	Homo sapiens (human)
spindle microtubule	Aurora kinase B	Homo sapiens (human)
spindle midzone	Aurora kinase B	Homo sapiens (human)
microtubule organizing center	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
centrosome	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule organizing center	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytosol	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule cytoskeleton	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
dendrite	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
midbody	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
neuron projection	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
gamma-tubulin complex	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
ciliary basal body	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
Golgi membrane	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
plasma membrane	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
intracellular anatomical structure	Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)
pericentriolar material	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 15	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 15	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 15	Homo sapiens (human)
nucleus	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
cytosol	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
cytosol	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
nucleus	PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
nucleus	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
nucleoplasm	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
cytoplasm	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
EKC/KEOPS complex	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
cytosol	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
nucleus	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
nucleus	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
nucleoplasm	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
nuclear body	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
nucleus	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
cytoplasm	Dual specificity testis-specific protein kinase 2	Homo sapiens (human)
nucleus	SRSF protein kinase 1	Homo sapiens (human)
nucleoplasm	SRSF protein kinase 1	Homo sapiens (human)
cytoplasm	SRSF protein kinase 1	Homo sapiens (human)
endoplasmic reticulum	SRSF protein kinase 1	Homo sapiens (human)
cytosol	SRSF protein kinase 1	Homo sapiens (human)
plasma membrane	SRSF protein kinase 1	Homo sapiens (human)
nuclear matrix	SRSF protein kinase 1	Homo sapiens (human)
nuclear speck	SRSF protein kinase 1	Homo sapiens (human)
chromatin	SRSF protein kinase 1	Homo sapiens (human)
nucleus	SRSF protein kinase 1	Homo sapiens (human)
cytoplasm	SRSF protein kinase 1	Homo sapiens (human)
Golgi membrane	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
nucleoplasm	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
nucleolus	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
endoplasmic reticulum	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
endoplasmic reticulum membrane	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
Golgi apparatus	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
cytosol	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
membrane	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
cytoplasm	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
nucleus	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
external side of plasma membrane	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein-containing complex	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase complex	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
IRE1-TRAF2-ASK1 complex	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
mRNA cleavage and polyadenylation specificity factor complex	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
nucleus	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
cytosol	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
focal adhesion	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
nuclear speck	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
lamellipodium	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
ruffle membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
cytosol	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
cytosol	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
nucleus	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
cytoplasm	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
preribosome, small subunit precursor	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
methyltransferase complex	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase RIO1	Homo sapiens (human)
nucleoplasm	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
cytosol	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
cytoplasm	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
nucleus	MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
preribosome, small subunit precursor	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase RIO2	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 19	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 19	Homo sapiens (human)
perinuclear region of cytoplasm	Cyclin-dependent kinase 19	Homo sapiens (human)
CKM complex	Cyclin-dependent kinase 19	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 19	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 19	Homo sapiens (human)
plasma membrane	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
brush border membrane	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
apical plasma membrane	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
plasma membrane	Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)
acrosomal vesicle	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
motile cilium	Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase 33	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 33	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 33	Homo sapiens (human)
nucleus	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleoplasm	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleolus	Nucleolar GTP-binding protein 1	Homo sapiens (human)
cytoplasm	Nucleolar GTP-binding protein 1	Homo sapiens (human)
cytosol	Nucleolar GTP-binding protein 1	Homo sapiens (human)
membrane	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nuclear membrane	Nucleolar GTP-binding protein 1	Homo sapiens (human)
perinuclear region of cytoplasm	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleolus	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase D2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase D2	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase DCLK3	Homo sapiens (human)
chromosome, telomeric region	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleus	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleoplasm	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleolus	RNA cytidine acetyltransferase	Homo sapiens (human)
membrane	RNA cytidine acetyltransferase	Homo sapiens (human)
midbody	RNA cytidine acetyltransferase	Homo sapiens (human)
telomerase holoenzyme complex	RNA cytidine acetyltransferase	Homo sapiens (human)
small-subunit processome	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleolus	RNA cytidine acetyltransferase	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
nucleus	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
cytoplasm	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
sarcomere	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
synapse	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
cytoplasm	Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)
cytoplasm	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cytosol	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cell leading edge	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
perinuclear region of cytoplasm	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
extracellular exosome	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
PML body	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
nucleus	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
nucleoplasm	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
cytoplasm	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
cytoplasmic stress granule	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
nuclear body	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
RNA polymerase II transcription regulator complex	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
nucleus	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
cytoplasm	Homeodomain-interacting protein kinase 2	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Srms	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Srms	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Srms	Homo sapiens (human)
cytosol	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
plasma membrane	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
nuclear body	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
cytoplasm	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
nucleus	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
PML body	Homeodomain-interacting protein kinase 3	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
Golgi stack	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
neuronal cell body	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PLK3	Homo sapiens (human)
nucleus	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleoplasm	dCTP pyrophosphatase 1	Homo sapiens (human)
mitochondrion	dCTP pyrophosphatase 1	Homo sapiens (human)
cytosol	dCTP pyrophosphatase 1	Homo sapiens (human)
cytosol	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK4	Homo sapiens (human)
nucleoplasm	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
nuclear body	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
PML body	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
nucleus	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytoplasm	MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
microtubule	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
nuclear speck	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek6	Homo sapiens (human)
cytosol	Casein kinase I isoform gamma-1	Homo sapiens (human)
nucleus	Casein kinase I isoform gamma-1	Homo sapiens (human)
plasma membrane	Casein kinase I isoform gamma-1	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-1	Homo sapiens (human)
fibrillar center	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
postsynaptic density	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cell junction	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
nucleus	SNF-related serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase LATS2	Homo sapiens (human)
extracellular region	Serine/threonine-protein kinase 36	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 36	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 36	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 36	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase 36	Homo sapiens (human)
cell projection	Serine/threonine-protein kinase 36	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 36	Homo sapiens (human)
cytoplasm	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
cytosol	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
phenylalanine-tRNA ligase complex	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
membrane	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
mitochondrial matrix	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
mitochondrion	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
nuclear speck	BMP-2-inducible protein kinase	Homo sapiens (human)
cytoplasm	BMP-2-inducible protein kinase	Homo sapiens (human)
nucleus	BMP-2-inducible protein kinase	Homo sapiens (human)
extracellular region	Obg-like ATPase 1	Homo sapiens (human)
nucleolus	Obg-like ATPase 1	Homo sapiens (human)
cytoplasm	Obg-like ATPase 1	Homo sapiens (human)
centrosome	Obg-like ATPase 1	Homo sapiens (human)
cytosol	Obg-like ATPase 1	Homo sapiens (human)
membrane	Obg-like ATPase 1	Homo sapiens (human)
platelet alpha granule lumen	Obg-like ATPase 1	Homo sapiens (human)
extracellular exosome	Obg-like ATPase 1	Homo sapiens (human)
cytoplasm	Obg-like ATPase 1	Homo sapiens (human)
nucleus	Midasin	Homo sapiens (human)
nucleoplasm	Midasin	Homo sapiens (human)
nucleolus	Midasin	Homo sapiens (human)
cytosol	Midasin	Homo sapiens (human)
membrane	Midasin	Homo sapiens (human)
intermediate filament cytoskeleton	Midasin	Homo sapiens (human)
nucleus	Midasin	Homo sapiens (human)
preribosome, large subunit precursor	Midasin	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cell surface	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
extrinsic component of plasma membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
extracellular space	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cytosol	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
endosome membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cyclin K-CDK12 complex	Cyclin-dependent kinase 12	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 12	Homo sapiens (human)
nuclear speck	Cyclin-dependent kinase 12	Homo sapiens (human)
nuclear cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 12	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 12	Homo sapiens (human)
cyclin/CDK positive transcription elongation factor complex	Cyclin-dependent kinase 12	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
centriole	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
chromatin	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
centriole	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK2	Homo sapiens (human)
nucleoplasm	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cytoplasm	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrion	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial inner membrane	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial respirasome	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial respiratory chain complex I	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial membrane	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
microtubule cytoskeleton	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MARK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase pim-2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
nuclear membrane	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
synapse	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 5	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 26	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 26	Homo sapiens (human)
Golgi-associated vesicle	Serine/threonine-protein kinase 26	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 26	Homo sapiens (human)
vesicle membrane	Serine/threonine-protein kinase 26	Homo sapiens (human)
membrane	Serine/threonine-protein kinase 26	Homo sapiens (human)
apical plasma membrane	Serine/threonine-protein kinase 26	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase 26	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 26	Homo sapiens (human)
cell periphery	Serine/threonine-protein kinase 26	Homo sapiens (human)
FAR/SIN/STRIPAK complex	Serine/threonine-protein kinase 26	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 26	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 26	Homo sapiens (human)
cytoplasm	eIF-2-alpha kinase GCN2	Homo sapiens (human)
cytosolic ribosome	eIF-2-alpha kinase GCN2	Homo sapiens (human)
cytosol	eIF-2-alpha kinase GCN2	Homo sapiens (human)
cytoplasm	eIF-2-alpha kinase GCN2	Homo sapiens (human)
nucleus	eIF-2-alpha kinase GCN2	Homo sapiens (human)
mitochondrion	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate-CoA ligase complex (ADP-forming)	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
extracellular exosome	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
mitochondrion	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate-CoA ligase complex	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase NLK	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase NLK	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase NLK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase NLK	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase NLK	Homo sapiens (human)
Golgi membrane	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
mitochondrial outer membrane	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
endosome	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
Golgi apparatus	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
cytosol	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
rough endoplasmic reticulum membrane	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
perinuclear region of cytoplasm	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
membrane	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
cytoplasm	Phosphatidylinositol 4-kinase beta	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 17A	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 17A	Homo sapiens (human)
nuclear speck	Serine/threonine-protein kinase 17A	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 17A	Homo sapiens (human)
nucleoplasm	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cytosol	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cell cortex	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
basolateral plasma membrane	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
apical plasma membrane	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cell body	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cytoplasm	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
cytosol	STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)
nucleoplasm	Ephrin type-A receptor 6	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 6	Homo sapiens (human)
dendrite	Ephrin type-A receptor 6	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 6	Homo sapiens (human)
extracellular space	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
intracellular membrane-bounded organelle	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
serine/threonine protein kinase complex	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
stress fiber	Septin-9	Homo sapiens (human)
cytoplasm	Septin-9	Homo sapiens (human)
microtubule	Septin-9	Homo sapiens (human)
axoneme	Septin-9	Homo sapiens (human)
actin cytoskeleton	Septin-9	Homo sapiens (human)
perinuclear region of cytoplasm	Septin-9	Homo sapiens (human)
non-motile cilium	Septin-9	Homo sapiens (human)
septin complex	Septin-9	Homo sapiens (human)
septin ring	Septin-9	Homo sapiens (human)
microtubule cytoskeleton	Septin-9	Homo sapiens (human)
cell division site	Septin-9	Homo sapiens (human)
cytoplasm	Death-associated protein kinase 2	Homo sapiens (human)
Golgi apparatus	Death-associated protein kinase 2	Homo sapiens (human)
cytoplasmic vesicle	Death-associated protein kinase 2	Homo sapiens (human)
autophagosome lumen	Death-associated protein kinase 2	Homo sapiens (human)
intracellular membrane-bounded organelle	Death-associated protein kinase 2	Homo sapiens (human)
cytoplasm	Death-associated protein kinase 2	Homo sapiens (human)
nucleus	Death-associated protein kinase 2	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
sarcolemma	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
GABA-ergic synapse	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
postsynaptic specialization membrane	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
voltage-gated potassium channel complex	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
dendritic spine	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
neuronal cell body	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
postsynaptic membrane	Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)
fibrillar center	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleolus	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
mitochondrion	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleus	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
nucleoplasm	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoplasm	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytosol	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoskeleton	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
apical plasma membrane	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
recycling endosome	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
extracellular exosome	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
presynapse	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
glutamatergic synapse	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
postsynaptic density, intracellular component	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoplasm	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)
actin cytoskeleton	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
axon	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytoplasmic vesicle membrane	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytoplasmic vesicle	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
neuron projection	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
dendritic growth cone	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
axonal growth cone	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
receptor complex	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 14	Homo sapiens (human)
membrane	Carbonic anhydrase 14	Homo sapiens (human)
basolateral plasma membrane	Carbonic anhydrase 14	Homo sapiens (human)
apical plasma membrane	Carbonic anhydrase 14	Homo sapiens (human)
plasma membrane	Carbonic anhydrase 14	Homo sapiens (human)
plasma membrane	ALK tyrosine kinase receptor	Homo sapiens (human)
plasma membrane	ALK tyrosine kinase receptor	Homo sapiens (human)
extracellular exosome	ALK tyrosine kinase receptor	Homo sapiens (human)
protein-containing complex	ALK tyrosine kinase receptor	Homo sapiens (human)
receptor complex	ALK tyrosine kinase receptor	Homo sapiens (human)
nucleoplasm	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
plasma membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
apical plasma membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
brush border membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
mitochondrial membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
membrane raft	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
external side of apical plasma membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
plasma membrane	Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)
cellular_component	SRSF protein kinase 3	Homo sapiens (human)
nucleus	SRSF protein kinase 3	Homo sapiens (human)
cytoplasm	SRSF protein kinase 3	Homo sapiens (human)
fibrillar center	Serine/threonine-protein kinase ICK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cilium	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ciliary basal body	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ciliary tip	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ciliary base	Serine/threonine-protein kinase ICK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cilium	Serine/threonine-protein kinase ICK	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 11A	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 11A	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 11A	Homo sapiens (human)
condensed chromosome	Aurora kinase C	Homo sapiens (human)
nucleus	Aurora kinase C	Homo sapiens (human)
cytoplasm	Aurora kinase C	Homo sapiens (human)
spindle	Aurora kinase C	Homo sapiens (human)
midbody	Aurora kinase C	Homo sapiens (human)
spindle midzone	Aurora kinase C	Homo sapiens (human)
chromosome passenger complex	Aurora kinase C	Homo sapiens (human)
kinetochore	Aurora kinase C	Homo sapiens (human)
spindle midzone	Aurora kinase C	Homo sapiens (human)
spindle pole centrosome	Aurora kinase C	Homo sapiens (human)
spindle microtubule	Aurora kinase C	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
mitochondrion	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
postsynaptic density	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
endocytic vesicle membrane	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
dendritic spine	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)
nucleus	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
membrane	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
mitochondrion	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
mitochondrion	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
cytoplasm	Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
actin cytoskeleton	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
membrane	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
glutamatergic synapse	Serine/threonine-protein kinase 38-like	Homo sapiens (human)
cytoplasm	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
cytoskeleton	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
plasma membrane	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
axon	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
dendrite	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
neuron projection	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
neuronal cell body	Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
exon-exon junction complex	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nucleus	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nucleoplasm	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear speck	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
extracellular exosome	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
mediator complex	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nucleoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
chromosome	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
nucleolus	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
nucleus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
nucleus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein-containing complex	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cytoplasm	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cell leading edge	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
Golgi membrane	Serine/threonine-protein kinase 24	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 24	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 24	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 24	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 24	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 24	Homo sapiens (human)
FAR/SIN/STRIPAK complex	Serine/threonine-protein kinase 24	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-3	Homo sapiens (human)
plasma membrane	Casein kinase I isoform gamma-3	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-3	Homo sapiens (human)
nucleus	Casein kinase I isoform gamma-3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
perinuclear region of cytoplasm	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (1197)

Assay ID	Title	Year	Journal	Article
AID624842	Binding constant for BMX kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424980	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID428371	Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1785173	Reduction in alpha-syn PFF-induced pS129 alpha-syn immunoreactivity in C57BL/6 mouse primary cortical neurons at 10 nM pretreated for 1 hr followed by exposed with alpha-syn PFF for 10 to 14 days by immunostaining based confocal fluorescence microscopy	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625022	Binding constant for MUSK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425166	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425094	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625130	Binding constant for FGFR4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424974	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1436039	Binding affinity to full length recombinant human CLK1 (M1 to I484 residues) expressed in bacterial expression system by KinomeScan assay	2017	European journal of medicinal chemistry, Jan-27, Volume: 126	Novel CLK1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands.
AID625082	Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624862	Binding constant for LYN kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624913	Binding constant for TYK2(JH2domain-pseudokinase) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424890	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865219	Inhibition of cell adhesion in human Escherichia coli stimulated-THP-1 cells by crystal violet staining based assay	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1454442	Displacement of CAT-1 from catalytic site of N-terminal His6-tagged ABL T315I mutant (unknown origin) at 25 uM by 19F NMR spectroscopy based dual-site competition assay	2017	ACS medicinal chemistry letters, Jun-08, Volume: 8, Issue:6
AID1757430	Inhibition of human c-KIT at 100 nM using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by radiometric assay relative to control	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID1425156	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724677	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL G250E mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID624735	Binding constant for ANKK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625143	Binding constant for CAMKK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624916	Binding constant for ULK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625107	Binding constant for DMPK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785157	Tmax in ICR mouse plasma at 5 mg/kg, po measured up to 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425190	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625115	Binding constant for PAK6 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624836	Binding constant for IKK-beta kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624969	Binding constant for ROCK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722266	Binding affinity to human FLT3	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID625117	Binding constant for PAK7 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624854	Binding constant for FLT4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425181	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624760	Binding constant for PFPK5(P.falciparum) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425062	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624943	Binding constant for ACVR1B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624987	Binding constant for ABL1(Q252H)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425213	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625081	Binding constant for RSK4(Kin.Dom.1-N-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624961	Binding constant for TGFBR1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624709	Binding constant for MYLK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624774	Binding constant for QSK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865217	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as suppression of CD49a expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs by flow cytometric analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID625076	Binding constant for PLK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424983	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625056	Binding constant for TESK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424988	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624948	Binding constant for CSK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624712	Binding constant for DYRK1A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286571	Antiproliferative activity against human CHL cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425189	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1886534	Vasculo-toxicity in human HMVEC cells assessed as reduction in vascular structure integrity at 10 uM measured after 6 hrs by calcein AM dye based fluorescence assay	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID624941	Binding constant for CDKL1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785196	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopamine transporters in striatum at 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624897	Binding constant for RAF1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425074	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865235	Inhibition of MK2 in Escherichia coli-stimulated human NCI-H929 cells assessed as reduction in MK2 phosphorylation pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 15 mins by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425160	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425140	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID732825	Antiproliferative activity against human K562 cells after 72 hrs by CCK8 assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1425163	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624968	Binding constant for DRAK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624817	Binding constant for MYO3B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624992	Binding constant for ABL1-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424909	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624907	Binding constant for SYK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1701216	Antiproliferative activity against human HCT-116 cells overexpressing DDR1 assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	2021	Bioorganic & medicinal chemistry, 01-01, Volume: 29	Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors.
AID1425043	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424943	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425065	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624917	Binding constant for MST3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1817046	Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
AID625011	Binding constant for FGR kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724977	Inhibition of human recombinant ABL1 G250E mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1424998	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625041	Binding constant for PIK3CA(H1047L) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722258	Inhibition of human c-Kit T670I mutant using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID624896	Binding constant for PRKR kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424917	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1854087	Inhibition of BCR-ABL (unknown origin)	2022	European journal of medicinal chemistry, Aug-05, Volume: 238	The progress of small-molecules and degraders against BCR-ABL for the treatment of CML.
AID1425047	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID722259	Inhibition of human c-Kit V654A mutant using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1425211	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865230	Inhibition of MK2 in Escherichia coli -stimulated human THP-1 cells assessed as reduction in p38alpha MAPK phosphorylation at 5 uM pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 15 mins by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1424929	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425014	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1186996	Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 24 hrs by Cell-Titer Glo assay	2014	Journal of medicinal chemistry, Oct-09, Volume: 57, Issue:19	Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
AID1648799	Inhibition of human ERG incubated for 4 hrs by competitive fluorescence tracer binding based assay	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID624706	Binding constant for MLK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424896	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785194	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-protein level in ventral mid brain at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624727	Binding constant for FYN kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785229	In vivo inhibition of alpha-syn PFF-induced c-Abl activation in C57BL/6 mouse PD model assessed as decrease in pY245-c-Abl protein level in ventral midbrain at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF stereotaxic injection f	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624761	Binding constant for CDC2L5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624873	Binding constant for PAK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624858	Binding constant for JAK1(JH2domain-pseudokinase) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425096	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID322453	Inhibition of Raf1 kinase	2008	Bioorganic & medicinal chemistry letters, Apr-01, Volume: 18, Issue:7	Pharmacophore identification of Raf-1 kinase inhibitors.
AID624769	Binding constant for AURKC kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1886530	Inhibition of ABL1 (unknown origin)	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID625136	Binding constant for YSK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1666984	Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-labelled P22 peptide as substrate preincubated for 10 mins followed by substrate addition and measured after 1	2020	Bioorganic & medicinal chemistry, 03-15, Volume: 28, Issue:6	A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
AID1207533	Inhibition of rapid delayed inward rectifying potassium current (IKr) measured using manual patch clamp assay
AID624831	Binding constant for CHEK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424889	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286555	Inhibition of TEL-BLK (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1386089	Inhibition of BCR-ABL1 E355G mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID625040	Binding constant for PIK3CA(E545K) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625031	Binding constant for MRCKB kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785161	Ratio of free drug level in brain to plasma of ICR mouse at 5 mg/kg, po measured up to 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624751	Binding constant for PIP5K1C kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286543	Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID515837	Antiproliferative activity against human GIST882 cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1424961	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515833	Inhibition of autophosphorylation of CSF1R expressed in HEK293 cells by ELISA	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1425138	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624963	Binding constant for LATS1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625046	Binding constant for PIK3CB kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286567	Antiproliferative activity against human MOLM14 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID428369	Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1425154	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286556	Inhibition of TEL-HCK (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1386084	Inhibition of BCR-ABL1 G250H mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID624850	Binding constant for DDR1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1207755	Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunits	2013	Scientific reports, , Volume: 3	MICE models: superior to the HERG model in predicting Torsade de Pointes.
AID1425084	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1240468	Inhibition of wild type Bcr-Abl (unknown origin) using Tyr2 peptide substrate after 2 hrs by FRET-based Z'-lyte assay	2015	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17	Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant.
AID1424954	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID732831	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID625020	Binding constant for ITK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624934	Binding constant for FLT3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1202713	Inhibition of DDR2 (unknown origin) assessed as reduction in collagen-induced DDR2 activation	2015	Journal of medicinal chemistry, Apr-23, Volume: 58, Issue:8	Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.
AID624985	Binding constant for ABL1(M351T)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1519875	Cytotoxicity against human LAMA84-s cells expressing IM-sensitive wild type Bcr/Abl assessed as reduction in cell viability incubated for 48 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID1785216	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in grip strength at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by grip strength test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425109	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624783	Binding constant for FGFR3(G697C) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1186995	Cytotoxicity against human HepG2 cells assessed as cell viability at 10 uM after 24 hrs by Cell-Titer Glo assay	2014	Journal of medicinal chemistry, Oct-09, Volume: 57, Issue:19	Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
AID1283290	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL T315I mutant after 72 hrs by MTT assay	2016	Journal of medicinal chemistry, Feb-11, Volume: 59, Issue:3	Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A.
AID625140	Binding constant for MARK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624729	Binding constant for FAK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724674	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL Y253H mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1757432	Inhibition of human FLT3 at 100 nM using EAIYAAPFAKKK as substrate in presence of [gamma-33P]-ATP by radiometric assay relative to control	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID1785230	In vivo inhibition of alpha-syn PFF-induced c-Abl activation in C57BL/6 mouse PD model assessed as decrease in pY245-c-Abl protein level in ventral midbrain at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF stereotaxic injection for 1 m	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425132	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1611402	Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID1519877	Cytotoxicity against human KBM5 cells expressing IM- sensitive wild type Bcr/Abl assessed as reduction in cell viability incubated for 48 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID624820	Binding constant for ACVR2B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624804	Binding constant for ERBB2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424993	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425038	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624767	Binding constant for MERTK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624991	Binding constant for ABL1-non phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424941	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1648809	Inhibition of VEGFR (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID625012	Binding constant for GAK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624802	Binding constant for PIM3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425167	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424995	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625088	Binding constant for ARK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624813	Binding constant for MINK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624837	Binding constant for IRAK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625032	Binding constant for TRKB kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1611401	Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID625125	Binding constant for CLK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425107	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1474167	Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status	2016	Drug discovery today, Apr, Volume: 21, Issue:4	DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
AID624770	Binding constant for CAMK2D kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624860	Binding constant for VEGFR2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624724	Binding constant for TAK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624810	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425144	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID463623	Inhibition of PDGFR	2010	Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4	Selectively nonselective kinase inhibition: striking the right balance.
AID724676	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL Q252H mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID722263	Inhibition of human c-Kit D816V mutant using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1424920	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625055	Binding constant for MST1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425057	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424935	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1817042	Cytotoxicity against mouse BAF3 cells expressing BCR-ABL T315I mutant assessed as inhibition of cell growth measured after 48 hrs by trypan blue assay
AID1425129	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624887	Binding constant for ERK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1918399	Cytotoxicity against human SH-SY5Y cells incubated for 48 hrs and measured by MTT assay	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID709936	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl H396R mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID625129	Binding constant for HIPK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID744877	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	2013	Bioorganic & medicinal chemistry, May-01, Volume: 21, Issue:9	Design, synthesis and biological activities of Nilotinib derivates as antitumor agents.
AID1785223	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse neuroinflammation PD model assessed as Iba-1 immunoreactivity in SNpc at 1 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF in to striatum for 1 month by by immunohistologi	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1424981	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625100	Binding constant for NLK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425203	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625124	Binding constant for RET(V804M) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID709997	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl M351T mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1666983	Inhibition of recombinant human His-tagged PCSK9 interaction with recombinant LDLR AB domain (unknown origin) measured after 3 hrs by horseradish peroxidase-coupled TMB substrate based spectrophotometry	2020	Bioorganic & medicinal chemistry, 03-15, Volume: 28, Issue:6	A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
AID625095	Binding constant for SIK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID590030	Antiproliferative activity against human KU812 cells	2011	Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7	Hybrid compounds as new Bcr/Abl inhibitors.
AID1865183	Antiinflammatory activity against LPS-stimulated human THP-1 cells assessed as disappearance inflammatory phenotype at 5 uM pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID428367	Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID624718	Binding constant for PFTAIRE2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425145	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425126	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724675	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL Y253F mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1496121	Ratio of drug level in CSF to plasma in human at 150 mg, po up to 5 hrs by mass spectrometric analysis	2018	Bioorganic & medicinal chemistry letters, 06-15, Volume: 28, Issue:11	Brain penetrant kinase inhibitors: Learning from kinase neuroscience discovery.
AID624829	Binding constant for CDK8 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624900	Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625006	Binding constant for EGFR(S752-I759del) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624990	Binding constant for ABL1(Y253F)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424986	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424952	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785218	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in pole climb down time at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by pole test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID421475	Antitumor activity against mouse BA/F3 cells expressing wild type Bcr-Abl xenografted in CB17 SCID mouse assessed as increase in mouse survival at 75 mg/kg, po administered on day 3 once daily for 19 days relative to control	2009	Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15	9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation.
AID1286570	Antiproliferative activity against human HEL cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425051	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1886532	Vasculo-toxicity in human HMVEC cells assessed as reduction in vascular structure integrity by measuring AUC measured after 6 hrs by calcein AM dye based fluorescence assay	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID1701215	Antiproliferative activity against human HCT-116 cells overexpressing DDR1 assessed as inhibition of cell proliferation at 10 uM measured after 72 hrs by MTT assay relative to control	2021	Bioorganic & medicinal chemistry, 01-01, Volume: 29	Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors.
AID1865221	Inhibition of P38 MAPK in Escherichia coli -stimulated human OCI-AML2 cells assessed as reduction in p38 MAPK phosphorylation pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 15 mins by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425046	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424975	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624797	Binding constant for PHKG2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785208	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse Le-wy body pathology PD model assessed as reduction in alpha-syn aggregates in TX-insoluble fraction in ventral midbrain at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1785195	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopamine transporters in striatum at 3 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1648802	Inhibition of PDGFRalpha (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1424953	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID732857	Inhibition of DDR2 (unknown origin) using fluorescein-labeled poly GAT as substrate incubated for 1 hr prior to substrate addition measured after 1 hr by TR-FRET assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1425142	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625090	Binding constant for ICK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865202	Inhibition of P38 MAPK pathway in Escherichia coli-stimulated human THP-1 cells assessed as reduction in IL-1beta expression at 5 uM pretreated for 1 hr followed by Escherichia coli stimulation and measured upto 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624989	Binding constant for ABL1(T315I)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1496117	Inhibition of Bcr-Abl (unknown origin)	2018	Bioorganic & medicinal chemistry letters, 06-15, Volume: 28, Issue:11	Brain penetrant kinase inhibitors: Learning from kinase neuroscience discovery.
AID1425169	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624703	Binding constant for MAPKAPK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625120	Binding constant for EPHA8 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624880	Binding constant for PIK4CB kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624823	Binding constant for MKNK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425089	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624947	Binding constant for BRAF(V600E) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865225	Antiinflammatory activity against LPS-stimulated human primary monocyte cells assessed reduction in TNFalpha level measured at 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624906	Binding constant for S6K1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625048	Binding constant for PRKCD kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625063	Binding constant for PLK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625027	Binding constant for MAP3K4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1242637	Antiproliferative activity against human NCI-H2286 cells expressing DDR2 mutant after 72 hrs by alamar blue assay	2015	ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7	Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors.
AID515829	Inhibition of human PDGFRalpha autophosphorylation in human A31 cells by ELISA	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID515830	Inhibition of human KIT autophosphorylation in human GIST882 cells by ELISA	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1785188	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopaminergic neuron in SNpc at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425093	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624932	Binding constant for CLK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424965	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425175	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515834	Antiproliferative activity against human K562 cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1283286	Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by MTT assay	2016	Journal of medicinal chemistry, Feb-11, Volume: 59, Issue:3	Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A.
AID1425102	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1875885	Volume of distribution at steady state in CD-1 mouse plasma at 10 mg/kg, iv at 0.083 hrs LC-MS/MS analysis	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID724668	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL M351T mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1785197	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopamine transporters in striatum at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624780	Binding constant for CDK4-cyclinD1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424921	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424933	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865191	Thermal stabilization of LPS-stimulated P38alpha in human THP-1 cells at 5 uM pretreated for 1 hr followed by LPS-stimulation and measured after 15 min by western blot based cellular thermal shift assay	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1207473	Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using IonWorks Quattro automated patch clamp platform
AID625033	Binding constant for PCTK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624754	Binding constant for NEK7 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425128	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624772	Binding constant for AURKB kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424898	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425136	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625110	Binding constant for TRPM6 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624904	Binding constant for NEK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625003	Binding constant for EGFR(L858R) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624749	Binding constant for CASK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425182	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624933	Binding constant for PLK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625009	Binding constant for EPHA3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648806	Inhibition of LCK (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID625111	Binding constant for RIOK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625083	Binding constant for LATS2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624816	Binding constant for HPK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625108	Binding constant for MKNK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425061	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424977	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID722274	Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1785226	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse neuroinflammation PD model assessed as Glial fibrillary acidic protein level in ventral midbrain at 1 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF in to striatum for 1	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID732828	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1817039	Cytotoxicity against mouse BAF3 cells expressing native BCR-ABL assessed as inhibition of cell growth measured after 72 hrs by MTT assay
AID624918	Binding constant for DYRK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1817045	Cytotoxicity against human U-937 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
AID1611410	Inhibition of BCR/Abl P190 mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID624949	Binding constant for CSNK1G3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722261	Binding affinity to human PDGFRalpha	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID625052	Binding constant for PRKG1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625094	Binding constant for CDK11 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865208	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as decrease in CD44 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624891	Binding constant for JNK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724980	Inhibition of human recombinant ABL1 T315I mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID590028	Inhibition of Bcr/Abl by FRET-based Z-lyte assay	2011	Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7	Hybrid compounds as new Bcr/Abl inhibitors.
AID624921	Binding constant for MAP4K3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID732830	Antiproliferative activity against human NCI-H23 cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID624867	Binding constant for MLK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425053	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624762	Binding constant for DLK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425108	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515826	Inhibition of autophosphorylation of DDR2 expressed in HEK293 cells by ELISA	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID624976	Binding constant for PRKX kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425042	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425067	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID732827	Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1425198	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286550	Inhibition of BCR/ABL p210 (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID709935	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl Y253F mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID625004	Binding constant for EGFR(L858R,T790M) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648803	Inhibition of SRC (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1865233	Binding affinity to P38alpha (unknown origin) measured at 0.05 to 333.33 nM after 600 secs by SPR analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624919	Binding constant for AURKA kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425177	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1207289	Inhibition of long-lasting type calcium current (ICaL) in HEK293 cells (alpha1C/beta2a/alpha2delta1) cells measured using IonWorks Barracuda automated patch clamp platform
AID1912478	Inhibition of the Organic Cation Transporter 3 (OCT3, SLC22A3) as assessed by a phenotypic impedance-based assay detecting changes in cell morphology by MPP+ uptake in HEK-293 JumpIN-SLC22A3 cells (PubChem AID: 1745861)	2022	International journal of molecular sciences, Jan-21, Volume: 23, Issue:3	MPP
AID1425076	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425171	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625123	Binding constant for RET(V804L) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424908	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624910	Binding constant for TTK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1519876	Cytotoxicity against IM resistant human LAMA84-r cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID329192	Inhibition of LPS-induced Btk autophosphorylation on Tyr223 in human U937 cells after 1 hr	2007	Proceedings of the National Academy of Sciences of the United States of America, Aug-14, Volume: 104, Issue:33	The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.
AID624959	Binding constant for MAP4K2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425134	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425151	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624806	Binding constant for RPS6KA4(Kin.Dom.1-N-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1337173	Inhibition of kinobead binding to NQO2 in human K562 cells incubated for 30 mins by iTRAQ reagent-based mass spectrometric method	2017	Nature reviews. Drug discovery, Jun, Volume: 16, Issue:6	Non-kinase targets of protein kinase inhibitors.
AID1785175	Reduction in alpha-syn PFF-induced TX-insoluble alpha-syn accumulation in C57BL/6 mouse primary cortical neurons at 10 nM pretreated for 1 hr followed by exposed with alpha-syn PFF for 10 to 14 days by Western blotting analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624908	Binding constant for TEC kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425058	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624827	Binding constant for CAMK2B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1240407	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl T315I mutant after 72 hrs by CCK-8 assay	2015	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17	Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant.
AID624782	Binding constant for FGFR3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624869	Binding constant for NEK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624877	Binding constant for PIK3C2B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624871	Binding constant for PAK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624828	Binding constant for CDK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425039	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425113	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625053	Binding constant for PRKG2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425071	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1873222	Inhibition of human ABCG2 expressed in human HEK293 cells membrane vesicles mediated transport of 3[H]-MTX for 1 hr using [3H]-methotrexate as substrate by rapid filtration technique	2022	European journal of medicinal chemistry, Jul-05, Volume: 237	Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
AID624863	Binding constant for MARK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1886523	Growth inhibition of human K562 cells measured after 48 hrs by alamarblue assay	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID625017	Binding constant for TIE1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID709991	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl H396P mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID625074	Binding constant for IKK-epsilon kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624801	Binding constant for MAP3K15 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424924	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1666986	Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system using FAM-labelled P22 peptide as substrate preincubated for 10 mins followed by substrate addition and me	2020	Bioorganic & medicinal chemistry, 03-15, Volume: 28, Issue:6	A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
AID724669	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL F317V mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID624923	Binding constant for MAPKAPK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425050	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624705	Binding constant for MYLK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624876	Binding constant for PDPK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625026	Binding constant for MAP3K1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865187	Antiinflammatory activity against LPS-stimulated human THP-1 cells assessed as TNF-alpha secretion pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624966	Binding constant for DCAMKL1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648797	Metabolic stability in mouse liver microsomes assessed as half life at 3 uM measured up to 30 mins in presence of NADPH by LS-MS/MS analysis	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1817043	Cytotoxicity against human K562 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
AID1425037	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424910	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID463625	Inhibition of wild type Abl	2010	Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4	Selectively nonselective kinase inhibition: striking the right balance.
AID624786	Binding constant for KIT kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624931	Binding constant for CLK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624758	Binding constant for RIPK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424891	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424918	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625101	Binding constant for TAOK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624716	Binding constant for CSNK1D kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625037	Binding constant for PIK3CA(C420R) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1611403	Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID1424990	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1386087	Inhibition of BCR-ABL1 E255K mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID624811	Binding constant for PAK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785225	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse neuroinflammation PD model assessed as Iba-1 protein level in ventral midbrain at 1 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF in to striatum for 1 month by Western b	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1648801	Inhibition of DDR2 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1286562	Inhibition of BCR/ABL p210-Y253F mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID624790	Binding constant for KIT(L576P) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID677646	Antiangiogenic activity in HUVEC co-cultured with vascular smooth muscle cells assessed as inhibition of network formation at 10 to 15 uM after 72 hrs	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
AID1865211	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as decrease in MMP9 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1424905	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1611406	Inhibition of BCR/Abl F317L mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID428366	Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1785186	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopaminergic neuron in SNpc at 3 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425135	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425148	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625071	Binding constant for STK39 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425192	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624962	Binding constant for ASK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624993	Binding constant for ABL2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625016	Binding constant for SRC kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625035	Binding constant for PHKG1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785198	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-protein level in ventral mid brain at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624830	Binding constant for CDK9 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624856	Binding constant for GSK3B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865195	Thermal stabilization of LPS-stimulated MKK4 in human THP-1 cells assessed as upregulation of protein at 5 uM pretreated for 1 hr followed by LPS-stimulation and measured after 15 min by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425010	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424948	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1386088	Inhibition of BCR-ABL1 E255V mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID1240405	Antiproliferative activity against human K562 cells expressing wild type Bcr-Abl after 72 hrs by CCK-8 assay	2015	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17	Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant.
AID744878	Inhibition of Bcr-Abl kinase (unknown origin) after 30 mins by HTRF assay	2013	Bioorganic & medicinal chemistry, May-01, Volume: 21, Issue:9	Design, synthesis and biological activities of Nilotinib derivates as antitumor agents.
AID1425028	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625021	Binding constant for LIMK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425070	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425170	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624874	Binding constant for PCTK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865212	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as decrease in TLR2 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1207567	Inhibition of long-lasting type calcium current (hICa) in Chinese Hamster Ovary (CHO) cells expressing hCav1.2 measured using IonWorks Quattro automated patch clamp platform
AID1666985	Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 peptide as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr in presenc	2020	Bioorganic & medicinal chemistry, 03-15, Volume: 28, Issue:6	A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
AID1424939	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424944	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624734	Binding constant for YANK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425115	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624972	Binding constant for MTOR kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1283298	Resistance index, ratio IC50 for mouse BA/F3 cells expressing BCR-ABL T315I mutant to IC50 for human K562 cells	2016	Journal of medicinal chemistry, Feb-11, Volume: 59, Issue:3	Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A.
AID624719	Binding constant for GRK7 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID515828	Inhibition of PDGFRbeta autophosphorylation in human A31 cells by ELISA	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1386051	Inhibition of BCR-ABL1 T315I mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID1865198	Inhibition of P38 MAPK pathway in Escherichia coli-stimulated human THP-1 cells assessed as reduction in TNFalpha expression at 5 uM pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1424984	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865215	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as suppression of CD11c expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs by flow cytometric analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1865216	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as suppression of CD14 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID625068	Binding constant for NEK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624746	Binding constant for WEE2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625005	Binding constant for EGFR(L861Q) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624764	Binding constant for CLK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624841	Binding constant for BLK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865213	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as upregulation of MMP9 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID625013	Binding constant for LCK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624826	Binding constant for BMPR2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625001	Binding constant for EGFR(L747-S752del, P753S) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424915	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515838	Antiproliferative activity against mouse M-NFS-60 cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1425195	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1141137	Inhibition of DDR2 T654M mutant (unknown origin) preincubated for 30 mins before substrate addition by FRET assay	2014	Journal of medicinal chemistry, May-22, Volume: 57, Issue:10	Identification of type II and III DDR2 inhibitors.
AID624771	Binding constant for TLK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID428460	Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID624859	Binding constant for JAK1(JH1domain-catalytic) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624835	Binding constant for ERN1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624915	Binding constant for PIP5K2B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865220	Inhibition of P38 MAPK in Escherichia coli -stimulated human NCI-H929 cells assessed as reduction in p38 MAPK phosphorylation pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 15 mins by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624944	Binding constant for ALK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624759	Binding constant for PFCDPK1(P.falciparum) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625092	Binding constant for NDR2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625085	Binding constant for ULK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425004	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624809	Binding constant for MYLK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425003	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID722272	Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1425044	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724985	Cytotoxicity against mouse BA/F3 cells expressing wild type BCR-ABL assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1424959	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424949	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1666987	Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labelled P4 peptide as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr	2020	Bioorganic & medicinal chemistry, 03-15, Volume: 28, Issue:6	A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
AID1519874	Cytotoxicity against human KU812 cells expressing IM- sensitive wild type Bcr/Abl assessed as reduction in cell viability incubated for 48 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID1865232	Inhibition of LPS-stimulated wildtype p38alpha MAPK expressed in human HEK293 cells assessed as reduction in IL-6 level at 5 uM pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by RT-qPCR analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425026	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624776	Binding constant for PCTK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425077	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865199	Inhibition of p38alpha MAPK in Escherichia coli -stimulated human THP-1 cells assessed as reduction in p38alpha MAPK phosphorylation at 5 uM pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 15 mins by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624935	Binding constant for FLT3(D835H) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624773	Binding constant for AMPK-alpha1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID709937	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl F359V mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1648798	Inhibition of human recombinant CYP3A4 expressed in insect cell microsomes in presence of NADPH by fluorescence assay	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1875887	Volume of distribution at steady state in Han-Wistar rat plasma at 5 mg/kg, iv at 0.083 hrs LC-MS/MS analysis	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID1207379	Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using IonWorks Quattro automated patch clamp platform
AID1425209	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624909	Binding constant for TGFBR2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425146	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425105	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425030	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1648795	Metabolic stability in human liver microsomes assessed as half life at 3 uM measured up to 30 mins in presence of NADPH by LS-MS/MS analysis	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID624925	Binding constant for RIPK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID732824	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1425158	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424967	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624747	Binding constant for SgK110 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724979	Inhibition of human recombinant ABL1 E255K mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1918400	Cytotoxicity against rat H9c2 cells incubated for 48 hrs and measured by MTT assay	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID624996	Binding constant for EGFR kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1876260	Inhibition of Abl (unknown origin)	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Kinase Inhibitors as Underexplored Antiviral Agents.
AID1424923	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID732829	Antiproliferative activity against human NCI-H460 cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID625142	Binding constant for TSSK1B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1386050	Inhibition of wild type BCR-ABL1 (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID1424946	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624784	Binding constant for INSR kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785228	In vivo inhibition of alpha-syn PFF-induced c-Abl activation in C57BL/6 mouse PD model assessed as decrease in pY245-c-Abl immunoreactivity in TH-positive neuron in SNpc at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF stereotaxic inje	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1865190	Thermal stabilization of LPS-stimulated P38alpha in human THP-1 cells assessed as thermal denaturation at 5 uM pretreated for 1 hr followed by LPS-stimulation and measured after 15 min by western blot based cellular thermal shift assay	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1845984	Antiproliferative activity against human Daoy cells assessed as inhibition of cell growth incubated for 72 hrs by Alamar blue dye based fluorescence spectrophotometric assay	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Medulloblastoma drugs in development: Current leads, trials and drawbacks.
AID1424913	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424931	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424904	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286569	Antiproliferative activity against human MEG01 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID624848	Binding constant for CSNK2A1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625097	Binding constant for TNNI3K kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624889	Binding constant for JNK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624964	Binding constant for DYRK1B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724673	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL E255V mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1425137	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624849	Binding constant for CSNK2A2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425188	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625128	Binding constant for CSNK1G1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID709995	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl Q252H mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1286551	Inhibition of TEL-SRC (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1589060	Inhibition of cell expansion in human KCL22 cells at 10 nM incubated for 48 hrs by trypan blue dye exclusion counting method	2019	Bioorganic & medicinal chemistry letters, 09-15, Volume: 29, Issue:18	An investigation of targeted inhibition of transcription factor activity with pyrrole imidazole polyamide (PA) in chronic myeloid leukemia (CML) blast crisis cells.
AID724671	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL T315I mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID624711	Binding constant for STK35 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624982	Binding constant for ABL1(F317L)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1454437	Displacement of CAT-1 from catalytic site of N-terminal His6-tagged ABL (83 to 534 residues) (unknown origin) expressed in Escherichia coli co-expressing Protein Tyrosine Phosphatase 1b at 25 uM by 19F NMR spectroscopy based dual-site competition assay	2017	ACS medicinal chemistry letters, Jun-08, Volume: 8, Issue:6
AID1424997	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1207439	Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWorks Quattro automated patch clamp platform
AID624998	Binding constant for EGFR(G719C) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1519878	Cytotoxicity against human KBM5 cells expressing IM-resistant Bcr/Abl T315I mutant assessed as reduction in cell viability incubated for 48 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID724667	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL E355G mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID624722	Binding constant for MKK7 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425116	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425054	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625134	Binding constant for PIP5K2C kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785214	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in number of turns at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by amphetamine rotation test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID722275	Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1424991	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425097	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425009	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624745	Binding constant for PKN1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1876259	Antiviral activity against SARS-CoV infected in african green monkey Vero E6 cells measured after 50 hrs by cell-titre glo assay	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Kinase Inhibitors as Underexplored Antiviral Agents.
AID624710	Binding constant for SRMS kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1916983	Cytotoxicity against HEK293 cells expressing ABCG2-482-R in presence of methotrexate	2022	European journal of medicinal chemistry, Nov-05, Volume: 241	Updated chemical scaffolds of ABCG2 inhibitors and their structure-inhibition relationships for future development.
AID722273	Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID624795	Binding constant for MET(M1250T) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425023	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1918398	Inhibition of full-length N-terminal His-tagged human c-Abl kinase (2 to 1130 residues) expressed in baculovirus expression system using Tk-substrate preincubated for 5 to 10 mins followed by substrate addition and measured after 40 mins by HTRF assay	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID624938	Binding constant for FLT3(K663Q) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425208	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624902	Binding constant for MEK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648808	Inhibition of NEK6 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1425073	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424911	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286625	Binding affinity to P38-alpha (unknown origin)	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1865237	Antiinflammatory activity against LPS-stimulated patient derived primary AML cells assessed reduction in TNFalpha level measured at 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1918403	Neuroprotective activity against MPP+-induced cell death in human SH-SY5Y cells assessed as increase in cell viability at 0.08 to 20 uM measured after 48 hrs by propidium iodide staining method	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID1865184	Antiinflammatory activity against LPS-stimulated human THP-1 cells assessed as reduction in TNFalpha level pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1186991	Cytotoxicity against human HepG2 cells assessed as cell viability at 1 uM after 4 hrs by Cell-Titer Glo assay	2014	Journal of medicinal chemistry, Oct-09, Volume: 57, Issue:19	Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
AID428368	Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID625073	Binding constant for SGK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624870	Binding constant for NEK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425121	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625079	Binding constant for NEK6 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625060	Binding constant for CAMKK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624920	Binding constant for MRCKA kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625109	Binding constant for BIKE kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424996	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1886531	Inhibition of ABL1 T315I mutant (unknown origin)	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID1337172	Inhibition of kinobead binding to DDR1 in human K562 cells incubated for 30 mins by iTRAQ reagent-based mass spectrometric method	2017	Nature reviews. Drug discovery, Jun, Volume: 16, Issue:6	Non-kinase targets of protein kinase inhibitors.
AID1865209	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as decrease in ICAM-1 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624955	Binding constant for EPHB3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865192	Thermal stabilization of P38 in human THP-1 cells at 5 uM measured after 15 min by TPP analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1424969	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424925	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424894	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424970	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286568	Antiproliferative activity against human MV4-11 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425110	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624864	Binding constant for CTK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624794	Binding constant for MET kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425207	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425212	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624882	Binding constant for PKAC-beta kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425072	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID709994	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl Y253H mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1425180	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID722270	Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1141140	Binding affinity to wild type DDR2 (unknown origin) by FLiK assay	2014	Journal of medicinal chemistry, May-22, Volume: 57, Issue:10	Identification of type II and III DDR2 inhibitors.
AID1425008	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286558	Inhibition of BCR/ABL p210-F317L mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID624924	Binding constant for RIPK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625086	Binding constant for SLK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624843	Binding constant for CAMK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425176	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424972	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID677648	Antiangiogenic activity in HUVEC co-cultured with vascular smooth muscle cells assessed as inhibition of network formation at 1.8 after 72 hrs	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
AID1648805	Inhibition of EPHB3 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID624757	Binding constant for PKMYT1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286553	Inhibition of TEL-DDR2 (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1424900	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1186992	Cytotoxicity against human HepG2 cells assessed as cell viability at 10 uM after 4 hrs by Cell-Titer Glo assay	2014	Journal of medicinal chemistry, Oct-09, Volume: 57, Issue:19	Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
AID724650	Inhibition of BCR-ABL T315I mutant in mouse BA/F3 cells after 4 hrs by Western blotting analysis	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1186993	Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 4 hrs by Cell-Titer Glo assay	2014	Journal of medicinal chemistry, Oct-09, Volume: 57, Issue:19	Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
AID624777	Binding constant for DDR2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624775	Binding constant for STK16 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624930	Binding constant for TNK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624789	Binding constant for KIT(D816V) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624872	Binding constant for PAK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425201	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624803	Binding constant for CHEK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624707	Binding constant for DCAMKL3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625062	Binding constant for MAP3K2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625066	Binding constant for IRAK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425019	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424922	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425187	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425081	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785215	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in pole climb down time at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by pole test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1815851	Aggregation in human HeLa cells expressing HSP27:GFP protein sensor assessed as number of HSP27:GFP foci per cell at 5 uM incubated for 48 hr by green fluorescent protein based confocal microscopy (rvb = 0.71)	2022	ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3	Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes.
AID1785191	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-positive fiber density at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by immune histochemical analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624974	Binding constant for PIK3CD kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785160	Ratio of total drug level in brain to plasma of ICR mouse at 5 mg/kg, po measured up to 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624903	Binding constant for SRPK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425133	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425027	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624815	Binding constant for ERBB4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865207	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as decrease in CD14 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624768	Binding constant for SRPK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625114	Binding constant for GSK3A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID590031	Antiproliferative activity against human imatinib-resistant K562 cells	2011	Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7	Hybrid compounds as new Bcr/Abl inhibitors.
AID1785190	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-positive fiber density at 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by immune histochemical analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625029	Binding constant for BRK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625045	Binding constant for PIK3CA(Q546K) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624853	Binding constant for FLT1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1242635	Inhibition of collagen I-induced DDR2 I638F mutant (unknown origin) phosphorylation expressed in HEK293 cells at 0.1 to 1 uM after 16 hrs by Western blotting	2015	ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7	Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors.
AID1424985	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424932	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724664	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL F486S mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1876144	Cytotoxicity against African green monkey Vero E6 cells at 250 nM	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID624732	Binding constant for PYK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625002	Binding constant for EGFR(L747-T751del,Sins) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286566	Antiproliferative activity against human U937 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425099	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424987	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624980	Binding constant for ABL1(F317I)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624708	Binding constant for CDC2L1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624781	Binding constant for CDK4-cyclinD3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625047	Binding constant for AMPK-alpha2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624999	Binding constant for EGFR(G719S) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624899	Binding constant for ROS1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624723	Binding constant for CSNK1A1L kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724976	Inhibition of human recombinant ABL1 H396P mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1286557	Inhibition of BCR/ABL p210-E255K mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425124	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625116	Binding constant for ADCK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865201	Inhibition of P38 MAPK pathway in Escherichia coli-stimulated human THP-1 cells assessed as reduction in IL-6 expression at 5 uM pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624978	Binding constant for ABL1(E255K)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625030	Binding constant for LOK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624894	Binding constant for MEK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1474166	Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index	2016	Drug discovery today, Apr, Volume: 21, Issue:4	DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
AID624890	Binding constant for p38-beta kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424994	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1886524	Growth inhibition of human K562 cells expressing BCR-ABL T315I mutant measured after 48 hrs by alamarblue assay	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID624721	Binding constant for MEK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865189	Thermal stabilization of LPS-stimulated P38gamma in human THP-1 cells assessed as change in melting temperature at 5 uM pretreated for 1 hr followed by LPS-stimulation and measured after 15 mins by thermal proteome profiling analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624742	Binding constant for NEK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625072	Binding constant for TBK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624960	Binding constant for RSK2(Kin.Dom.1-N-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425029	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID428374	Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID625067	Binding constant for NDR1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625014	Binding constant for PRKCE kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425056	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625043	Binding constant for PIK3CA(I800L) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624995	Binding constant for CSF1R kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624927	Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425083	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624833	Binding constant for CSNK1G2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425036	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1186994	Cytotoxicity against human HepG2 cells assessed as cell viability at 1 uM after 24 hrs by Cell-Titer Glo assay	2014	Journal of medicinal chemistry, Oct-09, Volume: 57, Issue:19	Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
AID1425141	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624884	Binding constant for PRKD1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425080	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624741	Binding constant for LRRK2(G2019S) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425082	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624973	Binding constant for JAK2(JH1domain-catalytic) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625091	Binding constant for MAST1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425022	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625121	Binding constant for RET kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624720	Binding constant for HIPK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624739	Binding constant for GRK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722269	Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID625099	Binding constant for TAOK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624983	Binding constant for ABL1(H396P)-non phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286563	Inhibition of BCR/ABL p210-H369P mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425060	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624971	Binding constant for DAPK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425147	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785189	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-positive fiber density at 3 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by immune histochemical analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID709990	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl E255K mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID624787	Binding constant for KIT(A829P) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865188	Thermal stabilization of LPS-stimulated P38alpha in human THP-1 cells assessed as change in melting temperature at 5 uM pretreated for 1 hr followed by LPS-stimulation and measured after 15 mins by thermal proteome profiling analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1875897	Antiviral activity against SARSCoV-2 African green monkey Vero E6 cells assessed as inhibition of viral replication by TCID50 assay	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID1876065	Inhibition of BCR-Abl (unknown origin)	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID1424968	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625098	Binding constant for IRAK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624956	Binding constant for EPHB4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425131	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424919	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425098	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1918402	Cytotoxicity against human L02 cells incubated for 48 hrs and measured by MTT assay	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID1424966	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624984	Binding constant for ABL1(H396P)-phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425210	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624812	Binding constant for SBK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865210	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as decrease in IL-1beta expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624796	Binding constant for MET(Y1235D) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624997	Binding constant for EGFR(E746-A750del) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424962	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624748	Binding constant for EPHA6 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624847	Binding constant for CSNK1E kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624940	Binding constant for FLT3(R834Q) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624901	Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722257	Inhibition of human c-Kit V650G mutant using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1425033	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1817044	Cytotoxicity against human KU812 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
AID624861	Binding constant for LIMK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624766	Binding constant for p38-gamma kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724975	Inhibition of human recombinant ABL1 M351T mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID709992	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl M244V mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID624912	Binding constant for TYK2(JH1domain-catalytic) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785211	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse Le-wy body pathology PD model assessed as reduction in pS129-alpha-syn in TX-insoluble fraction in ventral midbrain at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 m	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625087	Binding constant for MELK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624840	Binding constant for AXL kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785207	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse Le-wy body pathology PD model assessed as reduction in pS129-alpha-syn in TX-insoluble fraction in ventral midbrain at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF fo	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625084	Binding constant for HUNK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624954	Binding constant for EPHB1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1611408	Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID625039	Binding constant for PIK3CA(E545A) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1386086	Inhibition of BCR-ABL1 Y253H mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID624733	Binding constant for SIK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722268	Binding affinity to human ABL1	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1425125	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1286552	Inhibition of TEL-DDR1 (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1918419	Oral bioavailability in male Sprague-Dawley rat at 20 mg/kg measured by LC-MS/MS analysis	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID1785177	Reduction in alpha-syn PFF-induced pS129 alpha-syn accumulation in C57BL/6 mouse primary cortical neurons at 10 nM pretreated for 1 hr followed by exposed with alpha-syn PFF for 10 to 14 days by Western blotting analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425104	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624911	Binding constant for TXK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID677651	Antiangiogenic activity in HUVEC co-cultured with vascular smooth muscle cells assessed as inhibition of network formation at 0.15 uM after 72 hrs	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
AID1425130	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865214	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as upregulation of CD44 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1424978	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515835	Antiproliferative activity against BCR-ABL1 transfected mouse BA/F3 cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID625028	Binding constant for ASK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425143	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1240469	Inhibition of Bcr-Abl T315I mutant (unknown origin) using Tyr2 peptide substrate after 2 hrs by FRET-based Z'-lyte assay	2015	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17	Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant.
AID624970	Binding constant for CDK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624832	Binding constant for IKK-alpha kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424947	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1141136	Inhibition of wild type DDR2 (unknown origin) preincubated for 30 mins before substrate addition by FRET assay	2014	Journal of medicinal chemistry, May-22, Volume: 57, Issue:10	Identification of type II and III DDR2 inhibitors.
AID1424893	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865194	Thermal stabilization of LPS-stimulated MKK3 in human THP-1 cells assessed as upregulation of protein at 5 uM pretreated for 1 hr followed by LPS-stimulation and measured after 15 min by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425153	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724678	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL L248V mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1611404	Inhibition of BCR/Abl E255K mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID1425185	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1875882	Antiviral activity against SARSCoV-2	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID624824	Binding constant for PIP5K1A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1611405	Inhibition of BCR/Abl V299L mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID625069	Binding constant for TLK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624785	Binding constant for JAK3(JH1domain-catalytic) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624845	Binding constant for CDK7 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1611411	Inhibition of BCR/Abl P230 mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID732855	Inhibition of c-KIT (unknown origin) using Ser/Thr 6 peptide as substrate incubated for 1 hr prior to substrate addition measured after 2 hrs by FRET assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1425000	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425064	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625080	Binding constant for EIF2AK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624988	Binding constant for ABL1(T315I)-non phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425112	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624922	Binding constant for CAMK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785210	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse Le-wy body pathology PD model assessed as reduction in alpha-syn aggregates in TX-insoluble fraction in ventral midbrain at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF fo	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1207319	Inhibition of fast sodium current (INa) in Chinese Hamster Ovary (CHO) K1 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platform
AID1785227	In vivo inhibition of alpha-syn PFF-induced c-Abl activation in C57BL/6 mouse PD model assessed as decrease in pY245-c-Abl immunoreactivity in TH-positive neuron in SNpc at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF stereotaxi	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624893	Binding constant for MEK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425012	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785224	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse neuroinflammation PD model assessed as restoration of alpha-syn PFF-induced morphological abnormalities of astrocytes in SNpc at 1 to 10 mg/kg, po once a day for 5 months pretreated with alpha-	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625036	Binding constant for PIK3CA kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625025	Binding constant for MAK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785184	Reduction of alpha-syn PFF-induced Iba-1 immunoreactivity in mouse primary microglia at 10 nM treated for 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425006	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625138	Binding constant for STK33 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424950	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425068	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1525531	Binding affinity to ABL1 (unknown origin)	2019	Journal of medicinal chemistry, 11-27, Volume: 62, Issue:22	Why Some Targets Benefit from beyond Rule of Five Drugs.
AID1757431	Inhibition of human FLT3 at 10 nM using EAIYAAPFAKKK as substrate in presence of [gamma-33P]-ATP by radiometric assay relative to control	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID724666	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL E359V mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID722267	Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1785209	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse Le-wy body pathology PD model assessed as reduction in pS129-alpha-syn in TX-insoluble fraction in ventral midbrain at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 mo	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425161	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625059	Binding constant for YSK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625112	Binding constant for YANK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625019	Binding constant for AKT3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624778	Binding constant for ACVRL1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425159	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625089	Binding constant for AAK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625113	Binding constant for MARK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286559	Inhibition of BCR/ABL p210-F317I mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID624979	Binding constant for ABL1(F317I)-non phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1757433	Inhibition of human CSF1R at 10 nM using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by radiometric assay relative to control	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID724974	Inhibition of human recombinant ABL1 Y253F mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID624755	Binding constant for ZAK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624726	Binding constant for HIPK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424940	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625137	Binding constant for MEK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1496118	Drug uptake in mouse brain at 10 to 20 mg/kg, ip after 3 to 4 hrs by mass spectrometric analysis	2018	Bioorganic & medicinal chemistry letters, 06-15, Volume: 28, Issue:11	Brain penetrant kinase inhibitors: Learning from kinase neuroscience discovery.
AID1207503	Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) cells stable expressing hERG measured using IonWorks Barracuda automated patch clamp platform
AID1425191	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624737	Binding constant for EPHA5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624914	Binding constant for WEE1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865196	Thermal stabilization of LPS-stimulated MKK6 in human THP-1 cells assessed as upregulation of protein at 5 uM pretreated for 1 hr followed by Escherichia coli -stimulation and measured after 15 min by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID724984	Cytotoxicity against mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1425034	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425172	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624808	Binding constant for TRKA kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624844	Binding constant for CDK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624765	Binding constant for TRKC kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425086	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID709934	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl G250E mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1918397	Inhibition of full-length N-terminal His-tagged human c-Abl kinase (2 to 1130 residues) expressed in baculovirus expression system using Tk-substrate preincubated for 5 to 10 mins followed by substrate addition at 1 uM and measured after 40 mins by HTRF a	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID624875	Binding constant for PDGFRB kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625133	Binding constant for CDC2L2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425168	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625044	Binding constant for PIK3CA(M1043I) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID428370	Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1425048	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515827	Inhibition of autophosphorylation of DDR1 expressed in HEK293 cells by ELISA	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID624881	Binding constant for PKAC-alpha kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425155	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625127	Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID710011	Antiproliferative activity against mouse BA/F3 cells expressing wild type Bcr-Abl after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1425165	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625126	Binding constant for TAOK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785159	AUC (infinitive) in ICR mouse plasma at 5 mg/kg, po measured up to 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID421473	Antitumor activity against mouse BA/F3 cells expressing wild type Bcr-Abl xenografted in CB17 SCID mouse assessed as median survival time at 75 mg/kg, po administered on day 3 once daily for 19 days relative to control	2009	Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15	9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation.
AID625106	Binding constant for MARK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425174	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625008	Binding constant for EPHA1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625135	Binding constant for ADCK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625050	Binding constant for PKN2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1496120	Ratio of drug level in CSF to plasma in human at 300 mg, po up to 5 hrs by mass spectrometric analysis	2018	Bioorganic & medicinal chemistry letters, 06-15, Volume: 28, Issue:11	Brain penetrant kinase inhibitors: Learning from kinase neuroscience discovery.
AID625132	Binding constant for FGFR1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID677650	Antiangiogenic activity in HUVEC co-cultured with vascular smooth muscle cells assessed as inhibition of cell growth at 0.15 uM after 72 hrs	2012	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17	A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
AID1337170	Inhibition of kinobead binding to ABL in human K562 cells incubated for 30 mins by iTRAQ reagent-based mass spectrometric method	2017	Nature reviews. Drug discovery, Jun, Volume: 16, Issue:6	Non-kinase targets of protein kinase inhibitors.
AID624868	Binding constant for MST1R kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424907	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624839	Binding constant for AKT2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424971	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624888	Binding constant for ERK5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624883	Binding constant for PRKCI kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425078	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID722262	Binding affinity to human PDGFRbeata	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID624878	Binding constant for PIM1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID590029	Antiproliferative activity against human K562 cells	2011	Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7	Hybrid compounds as new Bcr/Abl inhibitors.
AID624819	Binding constant for ACVR1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624714	Binding constant for p38-alpha kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286560	Inhibition of BCR/ABL p210-M351T mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1153574	Antiproliferative activity against human BJ cells after 72 hrs by PrestoBlue colorimetric assay	2014	Bioorganic & medicinal chemistry letters, Jul-01, Volume: 24, Issue:13	Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives.
AID1425055	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624952	Binding constant for EPHA4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624834	Binding constant for DAPK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624986	Binding constant for ABL1(Q252H)-non phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1916984	Cytotoxicity against HEK293 cells expressing ABCG2-482-T7 in presence of methotrexate	2022	European journal of medicinal chemistry, Nov-05, Volume: 241	Updated chemical scaffolds of ABCG2 inhibitors and their structure-inhibition relationships for future development.
AID1424951	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424892	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1386090	Inhibition of BCR-ABL1 F359V mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID624798	Binding constant for LKB1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624958	Binding constant for PIK3C2G kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624865	Binding constant for MAP3K3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625093	Binding constant for TNIK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624731	Binding constant for CAMK2G kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624950	Binding constant for DMPK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425052	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624715	Binding constant for ERK8 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625078	Binding constant for SRPK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648800	Inhibition of ABL1 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1785187	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopaminergic neuron in SNpc at 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID732856	Inhibition of BCR/ABL (unknown origin) using tyrosine 2 peptide as substrate incubated for 1 hr prior to substrate addition measured after 2 hrs by FRET assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID624807	Binding constant for TNK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425100	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425020	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1519908	Induction of apoptotic cell death in human KBM5 cells expressing IM-sensitive wild type Bcr/Abl at 10 nM incubated for 48 hrs by Annexin V-staining based flow cytometry	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID625065	Binding constant for CIT kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286541	Antiproliferative activity against mouse BA/F3 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID624793	Binding constant for KIT(V559D,V654A) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1207409	Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells transfected with KCNQ1 / Kv1.7 / KvLQT1 and KCNE1/minK measured using IonWorks automated patch clamp platform
AID1701217	Antiproliferative activity against human MDA-MB-231 cells overexpressing DDR1 assessed as inhibition of cell proliferation at 10 uM measured after 72 hrs by MTT assay relative to control	2021	Bioorganic & medicinal chemistry, 01-01, Volume: 29	Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors.
AID1785193	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-protein level in ventral mid brain at 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625122	Binding constant for RET(M918T) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425152	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785217	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in number of turns at 1 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by amphetamine rotation test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID722265	Binding affinity to human DDR2	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID709933	Antiproliferative activity against mouse BA/F3 cells after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1425025	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425085	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425117	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425162	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624750	Binding constant for PRP4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624942	Binding constant for DRAK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID515832	Inhibition of BCR-ABL1 autophosphorylation in human K562 cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1242634	Inhibition of collagen I-induced DDR2 (unknown origin) phosphorylation expressed in HEK293 cells at 0.1 to 1 uM after 16 hrs by Western blotting	2015	ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7	Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors.
AID710013	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl T315I mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID624738	Binding constant for MLCK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624926	Binding constant for RIOK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625010	Binding constant for FER kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625105	Binding constant for EPHB2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424989	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1202712	Inhibition of DDR1b (unknown origin) assessed as reduction in collagen-induced DDR1b activation	2015	Journal of medicinal chemistry, Apr-23, Volume: 58, Issue:8	Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.
AID1286554	Inhibition of TEL-LCK (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1286565	Antiproliferative activity against human KU812 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425173	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624740	Binding constant for LRRK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724648	Inhibition of BCR-ABL T315I mutant-mediated STAT5 phosphorylation in mouse BA/F3 cells after 4 hrs by Western blotting analysis	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID625051	Binding constant for PRKCQ kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624994	Binding constant for AKT1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425204	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424899	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624885	Binding constant for ERK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624946	Binding constant for BRAF kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624792	Binding constant for KIT(V559D,T670I) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1519909	Induction of apoptotic cell death in human KBM5 cells expressing IM-resistant Bcr/Abl T315I mutant at 10 nM incubated for 48 hrs by Annexin V-staining based flow cytometry	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.
AID625103	Binding constant for MST4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624788	Binding constant for KIT(D816H) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625075	Binding constant for INSRR kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1496119	Drug uptake in mouse brain at 10 to 20 mg/kg, ip after 7 to 8 hrs by mass spectrometric analysis	2018	Bioorganic & medicinal chemistry letters, 06-15, Volume: 28, Issue:11	Brain penetrant kinase inhibitors: Learning from kinase neuroscience discovery.
AID624879	Binding constant for PIK3CG kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625096	Binding constant for STK36 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624928	Binding constant for CDKL2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865203	Inhibition of LPS-stimulated drug resitant p38alpha T106M mutant MAPK expressed in human HEK293 cells assessed as reduction in IL-6 level at 5 uM pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by RT-qPCR analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425088	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425045	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625007	Binding constant for EGFR(T790M) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865224	Antiinflammatory activity against Escherichia coli-stimulated human OCI-AML2 cells assessed reduction in IL-1beta level measured at 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425018	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424964	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624977	Binding constant for OSR1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425157	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424926	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1785199	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of dopamine transporters in striatum at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID624814	Binding constant for DCAMKL2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624713	Binding constant for ERK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624791	Binding constant for KIT(V559D) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425016	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625061	Binding constant for MAP4K5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425090	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424902	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425179	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624736	Binding constant for RPS6KA5(Kin.Dom.1-N-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648810	Inhibition of MAP4K3 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1785206	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse Le-wy body pathology PD model assessed as reduction in alpha-syn aggregates in TX-insoluble fraction in ventral midbrain at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn P	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1425079	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624822	Binding constant for CDKL3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624981	Binding constant for ABL1(F317L)-non phosphorylated kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625049	Binding constant for PRKCH kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1424934	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624779	Binding constant for BTK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425013	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425002	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724672	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL E255K mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID724670	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL F317L mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1757429	Inhibition of human c-KIT at 10 nM using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by radiometric assay relative to control	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID624730	Binding constant for CAMK2A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625058	Binding constant for VRK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624898	Binding constant for GRK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624763	Binding constant for RIPK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648807	Inhibition of EPHB4 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID1865218	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as suppression of CD54 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs by flow cytometric analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425178	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1701218	Antiproliferative activity against human MDA-MB-231 cells overexpressing DDR1 assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	2021	Bioorganic & medicinal chemistry, 01-01, Volume: 29	Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors.
AID1785219	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in grip strength at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by grip strength test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1865186	Antiinflammatory activity against LPS-stimulated human THP-1 cells assessed as reduction in IL-1beta level pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID625070	Binding constant for PFTK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID709993	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl E355G mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID624852	Binding constant for FES kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1611407	Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID1424960	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID515839	Antiproliferative activity mouse BA/F3 cells in presence of interleukin 3	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1785220	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in number of turns at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by amphetamine rotation test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1424912	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624945	Binding constant for BMPR1A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865236	Inhibition of MK2 in Escherichia coli-stimulated human OCI-AML2 cells assessed as reduction inMK2 phosphorylation pretreated for 1 hr followed by Escherichia coli stimulation and measured up to 15 mins by western blot analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1207349	Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platform
AID1425040	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624752	Binding constant for SNRK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624702	Binding constant for BRSK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624799	Binding constant for TIE2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425193	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1845986	Antiproliferative activity against human pateint derived Medulloblastoma cells assessed as inhibition of cell growth incubated for 72 hrs by Alamar blue dye based fluorescence spectrophotometric assay	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Medulloblastoma drugs in development: Current leads, trials and drawbacks.
AID1425059	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625015	Binding constant for ROCK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624937	Binding constant for FLT3(ITD) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625064	Binding constant for PIM2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865206	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as increase in Filamin-B expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1425095	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625018	Binding constant for YES kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID515831	Inhibition of autophosphorylation of BCR-ABL1 expressed in Ba/F cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID1425194	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424901	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID428372	Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1425122	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424958	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1757434	Inhibition of human CSF1R at 100 nM using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by radiometric assay relative to control	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID1141134	Binding affinity to human acrylodan-labeled N-terminal His-tagged DDR2 (558 to 855 aa) by FLiK assay	2014	Journal of medicinal chemistry, May-22, Volume: 57, Issue:10	Identification of type II and III DDR2 inhibitors.
AID1424937	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425196	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624939	Binding constant for FLT3(N841I) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648804	Inhibition of EPHB2 (unknown origin) assessed as residual activity at 10 uM incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID625054	Binding constant for MST2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722260	Inhibition of human c-Kit D816H mutant using poly[Glu:Tyr] (4:1) peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1785171	Decrease of alpha-syn PFF-induced pY245 c-Abl protein expression in C57BL/6 mouse primary cortical neurons at 10 nM pretreated for 1 hr followed by exposed with alpha-syn PFF for 10 to 14 days by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1865193	Antiinflammatory activity against Escherichia coli induced human THP-1 cells assessed as reduction in proinflammatory phenotype at 5 uM for 1 hr followed by Escherichia coli stimulation and measured upto 24 hrs by MALDI-TOF MS analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1424992	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1339539	Inhibition of full length human His6/GST-tagged NQO2 expressed in Escherichia coli Tuner(DE3)pLysS using menadione as substrate and CCHP as co-substrate preincubated with enzyme followed by substrate addition by MTT dye based continuous spectrophotometric	2017	ACS medicinal chemistry letters, Feb-09, Volume: 8, Issue:2	Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2.
AID722264	Binding affinity to human c-Kit	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID1425197	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1846058	Inhibition of hedgehog signalling in mouse NIH3T3 cells cotransfected with Gli/RE luciferase reporter gene assessed as Gli luciferase activity preincubated for 15 to 30 mins followed by ShhN stimulation and after 28 hrs by Steady-Glo reagent based lucifer	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Medulloblastoma drugs in development: Current leads, trials and drawbacks.
AID624951	Binding constant for EPHA2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1065976	Inhibition of human ABCG2 ATPase activity expressed in Sf9 insect cell membranes at 0.1 uM after 30 mins by colorimetric analysis relative to basal control in presence of sodium orthovanadate	2013	Journal of medicinal chemistry, Dec-27, Volume: 56, Issue:24	Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2.
AID1865185	Antiinflammatory activity against LPS-stimulated human THP-1 cells assessed as reduction in IL-6 level pretreated for 1 hr followed by LPS stimulation and measured upto 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID625131	Binding constant for FGFR2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425206	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624892	Binding constant for p38-delta kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425106	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624965	Binding constant for LZK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1875884	Volume of distribution at steady state in Beagle dog plasma at 1 mg/kg, iv at 0.083 hrs LC-MS/MS analysis	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID1785185	Reduction of alpha-syn PFF-induced iNOS immunoreactivity in mouse primary microglia at 10 nM treated for 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID515836	Antiproliferative activity against PDGFRbeta transfected mouse BA/F3 cells	2010	Bioorganic & medicinal chemistry, Oct-01, Volume: 18, Issue:19	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
AID624851	Binding constant for ERBB3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624717	Binding constant for JNK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625057	Binding constant for TYRO3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624800	Binding constant for IGF1R kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624743	Binding constant for LTK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785213	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in grip strength at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by grip strength test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625141	Binding constant for RIOK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425149	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425123	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865222	Antiinflammatory activity against Escherichia coli-stimulated human OCI-AML2 cells assessed reduction in TNFalpha level measured at 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624967	Binding constant for RPS6KA5(Kin.Dom.2-C-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624929	Binding constant for BRSK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425063	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425007	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625119	Binding constant for CAMK1G kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785212	Neuroprotective effect in alpha-syn PFF-induced C57BL/6 mouse motor behavioral deficit assessed as reduction in pole climb down time at 3 to 10 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by pole test	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID724981	Inhibition of human recombinant wild type ABL1 expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1425035	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID709996	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl F486S mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1425024	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1886527	Cytotoxicity against human iPSC-CM cells assessed as reduction in contractile alterations or amplitude in cell voltage by VF2.1.Cl dye based assay	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID1785192	Neuroprotective effect in C57BL/6 mouse assessed as prevention of alpha-syn PFF-induced loss of TH-protein level in ventral mid brain at 3 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF for 1 month by Western blot analysis	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1424928	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID625034	Binding constant for PDGFRA kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624838	Binding constant for ACVR2A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425202	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1865205	Inhibition of human Escherichia coli stimulated monocyte activation in human THP-1 cells assessed as increase in ROCK1 expression level at 5 uM pretreated for 1 hr and measured up to 24 hrs	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID624957	Binding constant for EPHB6 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625024	Binding constant for PRKD3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1286564	Inhibition of BCR/ABL p210-T315I mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID624753	Binding constant for PKNB(M.tuberculosis) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425075	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID428373	Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID624855	Binding constant for FRK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425118	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID732826	Antiproliferative activity against human T47D cells after 72 hrs by MTT assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID1424979	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425017	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID428458	Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID624756	Binding constant for MAP4K4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1648793	Inhibition of human ABL1 assessed as residual activity using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assay	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease.
AID625139	Binding constant for SNARK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425186	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624857	Binding constant for HCK kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625038	Binding constant for PIK3CA(E542K) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1153573	Antiproliferative activity against apoptosis-resistant, Philadelphia chromosome-positive human K562 cells after 72 hrs by PrestoBlue colorimetric assay	2014	Bioorganic & medicinal chemistry letters, Jul-01, Volume: 24, Issue:13	Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives.
AID624866	Binding constant for MLK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1757435	Inhibition of CSF1R in mouse MNFS-60 cells assessed as reduction in CSF-induced cell viability after 48 hrs by Ez-cytox reagent based assay	2021	European journal of medicinal chemistry, Apr-15, Volume: 216	Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
AID625000	Binding constant for EGFR(L747-E749del, A750P) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425087	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424936	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1386085	Inhibition of BCR-ABL1 Q252H mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID625118	Binding constant for CAMK1D kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1886533	Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue assay	2022	Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16	Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.
AID624846	Binding constant for CSNK1A1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID709938	Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl E255V mutant after 72 hrs by CCK-8 assay	2012	Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22	Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
AID1425119	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425164	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624821	Binding constant for YANK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624953	Binding constant for EPHA7 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID463624	Inhibition of KIT	2010	Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4	Selectively nonselective kinase inhibition: striking the right balance.
AID624805	Binding constant for RSK3(Kin.Dom.2-C-terminal) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID732858	Inhibition of DDR1 (unknown origin) using fluorescein-labeled poly GAT as substrate incubated for 1 hr prior to substrate addition measured after 1 hr by TR-FRET assay	2013	Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.
AID724978	Inhibition of human recombinant ABL1 Q252H mutant expressed in insect cells after 30 mins by FRET assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1424973	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425200	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1875886	Volume of distribution at steady state in cynomolgus monkey plasma at 3 mg/kg, iv at 0.083 hrs LC-MS/MS analysis	2022	Journal of medicinal chemistry, 01-27, Volume: 65, Issue:2	Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
AID1425150	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID428457	Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1425199	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1918401	Cytotoxicity against HEK293 cells incubated for 48 hrs and measured by MTT assay	2022	Bioorganic & medicinal chemistry, Nov-15, Volume: 74	Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.
AID624895	Binding constant for MEK6 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID724649	Inhibition of BCR-ABL T315I mutant-mediated CRK1 phosphorylation in mouse BA/F3 cells after 4 hrs by Western blotting analysis	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID1424945	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624936	Binding constant for FLT3(D835Y) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624886	Binding constant for ERK4 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1785158	Cmax in ICR mouse plasma at 5 mg/kg, po measured up to 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1424963	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1386091	Inhibition of BCR-ABL1 E459K mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of BCR-ABL1-mediated cell proliferation after 48 hrs by BriteLight luciferase assay	2018	Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.
AID1785156	Half life in ICR mouse plasma at 5 mg/kg, po measured up to 24 hrs	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID625077	Binding constant for DAPK2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1815855	Aggregation in human HeLa cells expressing HSP27:GFP protein in sensor assessed as HSP27:GFP foci area per cell at 5 uM incubated for 48 hrs by green fluorescent protein based confocal microscopy (rvb = 0.6)	2022	ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3	Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes.
AID1286561	Inhibition of BCR/ABL p210-Q252H mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay	2016	Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5	Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
AID1425111	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624744	Binding constant for ZAP70 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625104	Binding constant for MYO3A kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425001	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1611409	Inhibition of BCR/Abl H396P mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs by CellTiter-Glo luminescent cell viability assay	2019	Bioorganic & medicinal chemistry letters, 12-15, Volume: 29, Issue:24	Structure-based analysis and biological characterization of imatinib derivatives reveal insights towards the inhibition of wild-type BCR-ABL and its mutants.
AID624975	Binding constant for PLK1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625023	Binding constant for HIPK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1865223	Antiinflammatory activity against Escherichia coli-stimulated human OCI-AML2 cells assessed reduction in IL-6 level measured at 24 hrs by ELISA analysis	2022	Journal of medicinal chemistry, 09-22, Volume: 65, Issue:18	A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
AID1785125	In vivo inhibition of alpha-syn PFF-induced c-Abl activation in C57BL/6 mouse PD model assessed as decrease in pY245-c-Abl immunoreactivity in TH-positive neuron in SNpc at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF stereotaxic inj	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID1785231	In vivo inhibition of alpha-syn PFF-induced c-Abl activation in C57BL/6 mouse PD model assessed as decrease in pY245-c-Abl protein level in ventral midbrain at 30 mg/kg, po once a day for 5 months pretreated with alpha-syn PFF stereotaxic injection for 1	2021	Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20	A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson's Disease.
AID428459	Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay	2009	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15	The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
AID1424942	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425127	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID724665	Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL H396R mutant assessed as growth inhibition after 72 hrs by CCK-8 assay	2013	Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
AID625102	Binding constant for PRKD2 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425069	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624905	Binding constant for CDKL5 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624704	Binding constant for NEK9 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID625042	Binding constant for PIK3CA(H1047Y) kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1425049	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID624725	Binding constant for NEK11 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624728	Binding constant for NIM1 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID624818	Binding constant for ULK3 kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID722271	Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrate	2013	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3	Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.
AID624825	Binding constant for BMPR1B kinase domain	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
AID1347124	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for RD cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347089	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347117	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-37 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347095	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347107	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1296008	Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening	2020	SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1	Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347093	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347116	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SJ-GBM2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347082	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347127	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Saos-2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347090	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347104	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508591	NCATS Rat Liver Microsome Stability Profiling	2020	Scientific reports, 11-26, Volume: 10, Issue:1	Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
AID1347083	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID1347096	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347114	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for DAOY cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347125	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh18 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347115	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB-EBc1 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347111	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-MC cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347112	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-12 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347128	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for OHS-50 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347113	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for LAN-5 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508612	NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling	2017	Bioorganic & medicinal chemistry, 02-01, Volume: 25, Issue:3	Highly predictive and interpretable models for PAMPA permeability.
AID1347122	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for U-2 OS cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347110	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for A673 cells)	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347129	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-SH cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1346987	P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347154	Primary screen GU AMC qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347091	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347086	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347123	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh41 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347119	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for MG 63 (6-TG R) cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347102	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1346986	P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347100	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347097	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347121	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for control Hh wild type fibroblast cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347092	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347098	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347106	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630	Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay	2021	Cell reports, 04-27, Volume: 35, Issue:4	A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID686947	qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen	2013	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15	Identification of potent Yes1 kinase inhibitors using a library screening approach.
AID1347118	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for TC32 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347109	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB1643 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347126	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh30 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347105	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347160	Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347159	Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1645848	NCATS Kinetic Aqueous Solubility Profiling	2019	Bioorganic & medicinal chemistry, 07-15, Volume: 27, Issue:14	Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
AID1347411	qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary	2020	ACS chemical biology, 07-17, Volume: 15, Issue:7	High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1799594	In Vitro Kinase Assay from Article 10.1111/j.1747-0285.2009.00905.x: \\Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template.\\	2010	Chemical biology & drug design, Jan, Volume: 75, Issue:1	Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template.
AID1800098	EC50 Test from Article 10.1021/cb400430t: \\Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.\\	2013	ACS chemical biology, Oct-18, Volume: 8, Issue:10	Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.
AID1800272	Kinase Assays from Article 10.1111/cbdd.12272: \\Design, synthesis and biological evaluation of pyridin-3-yl pyrimidines as potent Bcr-Abl inhibitors.\\	2014	Chemical biology & drug design, May, Volume: 83, Issue:5	Design, synthesis and biological evaluation of pyridin-3-yl pyrimidines as potent Bcr-Abl inhibitors.
AID1802323	Kinobeads Competition Assay from Article 10.1021/acschembio.6b00709: \\Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.\\	2016	ACS chemical biology, 12-16, Volume: 11, Issue:12	Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.
AID1801733	Kinome-Wide Inhibitor Profiling for Phosphorylated c-Abl from Article 10.1021/acschembio.5b01018: \\Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity.\\	2016	ACS chemical biology, 05-20, Volume: 11, Issue:5	Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity.
AID1801713	Competition Binding Assays from Article 10.1021/acschembio.5b01063: \\Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.\\	2016	ACS chemical biology, 05-20, Volume: 11, Issue:5	Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
AID1802324	HotSpot Kinase Activity Assay from Article 10.1021/acschembio.6b00709: \\Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.\\	2016	ACS chemical biology, 12-16, Volume: 11, Issue:12	Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.
AID1801731	Kinome-Wide Inhibitor Profiling from Article 10.1021/acschembio.5b01018: \\Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity.\\	2016	ACS chemical biology, 05-20, Volume: 11, Issue:5	Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity.
AID1345524	Human discoidin domain receptor tyrosine kinase 2 (Type XVI RTKs: DDR (collagen receptor) family)	2013	ACS chemical biology, Oct-18, Volume: 8, Issue:10	Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.
AID1345562	Human discoidin domain receptor tyrosine kinase 1 (Type XVI RTKs: DDR (collagen receptor) family)	2013	ACS chemical biology, Oct-18, Volume: 8, Issue:10	Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.
AID1345606	Human ABL proto-oncogene 1, non-receptor tyrosine kinase (Abl family)	2005	Cancer research, Jun-01, Volume: 65, Issue:11	In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants.
AID977611	Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB	2011	Nature biotechnology, Oct-30, Volume: 29, Issue:11	Comprehensive analysis of kinase inhibitor selectivity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	214 (15.60)	29.6817
2010's	959 (69.90)	24.3611
2020's	199 (14.50)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	147 (10.45%)	5.53%
Reviews	227 (16.13%)	6.00%
Case Studies	177 (12.58%)	4.05%
Observational	21 (1.49%)	0.25%
Other	835 (59.35%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
adenine [no description available]	2.85	3	0	6-aminopurines; purine nucleobase	Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
betaine glycine betaine : The amino acid betaine derived from glycine.	3.23	1	0	amino-acid betaine; glycine derivative	fundamental metabolite
methane Methane: The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed). methane : A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).	2.08	1	0	alkane; gas molecular entity; mononuclear parent hydride; one-carbon compound	bacterial metabolite; fossil fuel; greenhouse gas
salicylic acid Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).	2.13	1	0	monohydroxybenzoic acid	algal metabolite; antifungal agent; antiinfective agent; EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor; keratolytic drug; plant hormone; plant metabolite
bupropion Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.. bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.	3.23	1	0	aromatic ketone; monochlorobenzenes; secondary amino compound	antidepressant; environmental contaminant; xenobiotic
3,4-dihydroxyphenylacetic acid 3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.. (3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.. dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.	3.59	1	1	catechols; dihydroxyphenylacetic acid	human metabolite
aminocaproic acid Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.. 6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.	3.23	1	0	amino acid zwitterion; epsilon-amino acid; omega-amino fatty acid	antifibrinolytic drug; hematologic agent; metabolite
creatine [no description available]	2.55	2	0	glycine derivative; guanidines; zwitterion	geroprotector; human metabolite; mouse metabolite; neuroprotective agent; nutraceutical
niacinamide nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.	8.84	32	0	pyridine alkaloid; pyridinecarboxamide; vitamin B3	anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor
niacin Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.. vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).. nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.	3.23	1	0	pyridine alkaloid; pyridinemonocarboxylic acid; vitamin B3	antidote; antilipemic drug; EC 3.5.1.19 (nicotinamidase) inhibitor; Escherichia coli metabolite; human urinary metabolite; metabolite; mouse metabolite; plant metabolite; vasodilator agent
nitrates Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.	2.5	2	0	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species
nitrites Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)	2.5	2	0	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species	human metabolite
pteridines [no description available]	2.49	2	0	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; pteridines
pyrazinamide pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.	3.23	1	0	monocarboxylic acid amide; N-acylammonia; pyrazines	antitubercular agent; prodrug
pyridoxamine [no description available]	2.15	1	0	aminoalkylpyridine; hydroxymethylpyridine; monohydroxypyridine; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite
pyridoxine 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source. vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).	3.23	1	0	hydroxymethylpyridine; methylpyridines; monohydroxypyridine; vitamin B6	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
thiamine thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.	3.23	1	0	primary alcohol; vitamin B1	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
thymine [no description available]	2.03	1	0	pyrimidine nucleobase; pyrimidone	Escherichia coli metabolite; human metabolite; mouse metabolite
uracil 2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder	2.03	1	0	pyrimidine nucleobase; pyrimidone	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; prodrug; Saccharomyces cerevisiae metabolite
uric acid Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.. uric acid : An oxopurine that is the final oxidation product of purine metabolism.. 6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.. 7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.	2.31	1	0	uric acid	Escherichia coli metabolite; human metabolite; mouse metabolite
b 844-39 [no description available]	3.73	2	0	diarylmethane
pk 11195 PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine	3.07	4	0	aromatic amide; isoquinolines; monocarboxylic acid amide; monochlorobenzenes	antineoplastic agent
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.49	2	0	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.	2.1	1	0	methylpyridines; phenylpyridine; tetrahydropyridine	neurotoxin
pd 173074 [no description available]	2.08	1	0	aromatic amine; biaryl; dimethoxybenzene; pyridopyrimidine; tertiary amino compound; ureas	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist
jtv519 [no description available]	2.89	3	0
homovanillic acid Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.. homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.. homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.	3.59	1	1	guaiacols; monocarboxylic acid	human metabolite; mouse metabolite
phenytoin [no description available]	3.61	2	0	imidazolidine-2,4-dione	anticonvulsant; drug allergen; sodium channel blocker; teratogenic agent
abt 702 [no description available]	2.08	1	0	bipyridines
acebutolol Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.. acebutolol : An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.	3.23	1	0	aromatic amide; ethanolamines; ether; monocarboxylic acid amide; propanolamine; secondary amino compound	anti-arrhythmia drug; antihypertensive agent; beta-adrenergic antagonist; sympathomimetic agent
acetaminophen Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.. paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.	3.95	3	0	acetamides; phenols	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; cyclooxygenase 3 inhibitor; environmental contaminant; ferroptosis inducer; geroprotector; hepatotoxic agent; human blood serum metabolite; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
acetazolamide Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)	3.58	2	0	monocarboxylic acid amide; sulfonamide; thiadiazoles	anticonvulsant; diuretic; EC 4.2.1.1 (carbonic anhydrase) inhibitor
acetohydroxamic acid acetohydroxamic acid: urease inhibitor. oxime : Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes.. N-hydroxyacetimidic acid : A carbohydroximic acid consisting of acetimidic acid having a hydroxy group attached to the imide nitrogen.. acetohydroxamic acid : A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group.	3.23	1	0	acetohydroxamic acids; carbohydroximic acid	algal metabolite; EC 3.5.1.5 (urease) inhibitor
rtki cpd [no description available]	3.51	1	0	aromatic ether; monochlorobenzenes; quinazolines	antineoplastic agent; antiviral agent; epidermal growth factor receptor antagonist; geroprotector
alaproclate alaproclate: specific 5-hydroxytryptamine uptake inhibitors; RN given refers to (DL)-isomer	3.23	1	0	alpha-amino acid ester
albendazole [no description available]	3.23	1	0	aryl sulfide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	anthelminthic drug; microtubule-destabilising agent; tubulin modulator
albuterol Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.. albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).	3.23	1	0	phenols; phenylethanolamines; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; environmental contaminant; xenobiotic
alendronate alendronic acid : A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.	3.23	1	0	1,1-bis(phosphonic acid); primary amino compound	bone density conservation agent; EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor
alfuzosin alfuzosin: structure given in first source	3.23	1	0	monocarboxylic acid amide; quinazolines; tetrahydrofuranol	alpha-adrenergic antagonist; antihypertensive agent; antineoplastic agent
alosetron alosetron : A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.	3.23	1	0	imidazoles; pyridoindole	antiemetic; gastrointestinal drug; serotonergic antagonist
alprazolam Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238). alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.	4.19	4	0	organochlorine compound; triazolobenzodiazepine	anticonvulsant; anxiolytic drug; GABA agonist; muscle relaxant; sedative; xenobiotic
altretamine Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.	3.23	1	0	triamino-1,3,5-triazine
amantadine amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source	3.23	1	0	adamantanes; primary aliphatic amine	analgesic; antiparkinson drug; antiviral drug; dopaminergic agent; NMDA receptor antagonist; non-narcotic analgesic
ambenonium ambenonium : A symmetrical oxalamide-based bis-quaternary ammonium ion having ethyl and 2-chlorobenzyl groups attached to the nitrogens.	3.23	1	0	quaternary ammonium ion	EC 3.1.1.8 (cholinesterase) inhibitor
diatrizoic acid Diatrizoate: A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.. amidotrizoic acid : A member of the class of benzoic acids that is benzoic acid having iodo substituents at the 2-, 4- and 6-positions and acetamido substituents at the 3- and 5-positions. It is used, mainly as its N-methylglucamine and sodium salts, as an X-ray contrast medium in gastrointestinal studies, angiography, and urography.	3.23	1	0	acetamides; benzoic acids; organoiodine compound	environmental contaminant; radioopaque medium; xenobiotic
amifostine anhydrous Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.. amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.	3.23	1	0	diamine; organic thiophosphate	antioxidant; prodrug; radiation protective agent
p-aminohippuric acid p-Aminohippuric Acid: The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.. p-aminohippurate : A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.. p-aminohippuric acid : An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.	3.23	1	0	N-acylglycine	Daphnia magna metabolite
theophylline [no description available]	3.23	1	0	dimethylxanthine	adenosine receptor antagonist; anti-asthmatic drug; anti-inflammatory agent; bronchodilator agent; drug metabolite; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; fungal metabolite; human blood serum metabolite; immunomodulator; muscle relaxant; vasodilator agent
amiodarone Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.. amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.	3.61	2	0	1-benzofurans; aromatic ketone; organoiodine compound; tertiary amino compound	cardiovascular drug
dan 2163 [no description available]	2.89	3	0	aromatic amide; aromatic amine; benzamides; pyrrolidines; sulfone	environmental contaminant; second generation antipsychotic; xenobiotic
amitriptyline Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.. amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.	3.69	2	0	carbotricyclic compound; tertiary amine	adrenergic uptake inhibitor; antidepressant; environmental contaminant; tropomyosin-related kinase B receptor agonist; xenobiotic
amlexanox amlexanox: SRA-A antagonist;structure given in first source. amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.	2.89	3	0	monocarboxylic acid; pyridochromene	anti-allergic agent; anti-ulcer drug; non-steroidal anti-inflammatory drug
amlodipine Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.. amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.	3.23	1	0	dihydropyridine; ethyl ester; methyl ester; monochlorobenzenes; primary amino compound	antihypertensive agent; calcium channel blocker; vasodilator agent
amoxapine Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.. amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.	3.23	1	0	dibenzooxazepine	adrenergic uptake inhibitor; antidepressant; dopaminergic antagonist; geroprotector; serotonin uptake inhibitor
anastrozole [no description available]	3.6	2	0	nitrile; triazoles	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
aspirin Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5). acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.. acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.	3.64	2	0	benzoic acids; phenyl acetates; salicylates	anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent
astemizole Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.. astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.	3.07	4	0	benzimidazoles; piperidines	anti-allergic agent; anticoronaviral agent; H1-receptor antagonist
atenolol Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.. atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.	3.23	1	0	ethanolamines; monocarboxylic acid amide; propanolamine	anti-arrhythmia drug; antihypertensive agent; beta-adrenergic antagonist; environmental contaminant; sympatholytic agent; xenobiotic
azathioprine Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed). azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.	3.23	1	0	aryl sulfide; C-nitro compound; imidazoles; thiopurine	antimetabolite; antineoplastic agent; carcinogenic agent; DNA synthesis inhibitor; hepatotoxic agent; immunosuppressive agent; prodrug
baclofen [no description available]	3.23	1	0	amino acid zwitterion; gamma-amino acid; monocarboxylic acid; monochlorobenzenes; primary amino compound	central nervous system depressant; GABA agonist; muscle relaxant
bendazac bendazac : A monocarboxylic acid that is glycolic acid in which the hydrogen attached to the 2-hydroxy group is replaced by a 1-benzyl-1H-indazol-3-yl group. Although it has anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties and has been used for the treatment of various inflammatory skin disorders, its principal effect is to inhibit the denaturation of proteins. Its lysine salt is used in the management of cataracts.	3.23	1	0	indazoles; monocarboxylic acid	non-steroidal anti-inflammatory drug; radical scavenger
bendroflumethiazide Bendroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810). bendroflumethiazide : A sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group.	3.23	1	0	benzothiadiazine; sulfonamide	antihypertensive agent; diuretic
benzbromarone Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.. benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.	4.91	5	0	1-benzofurans; aromatic ketone	uricosuric drug
bepridil Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.. bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.	2.08	1	0	pyrrolidines; tertiary amine	anti-arrhythmia drug; antihypertensive agent; calcium channel blocker; vasodilator agent
betaxolol [no description available]	3.23	1	0	propanolamine	antihypertensive agent; beta-adrenergic antagonist; sympatholytic agent
bethanechol Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.. bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.	3.23	1	0	carbamate ester; quaternary ammonium ion	muscarinic agonist
bicalutamide bicalutamide: approved for treatment of advanced prostate cancer. N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide : A member of the class of (trifluoromethyl)benzenes that is 4-amino-2-(trifluoromethyl)benzonitrile in which one of the amino hydrogens is substituted by a 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoyl group.. bicalutamide : A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism.	3.61	2	0	(trifluoromethyl)benzenes; monocarboxylic acid amide; monofluorobenzenes; nitrile; sulfone; tertiary alcohol
biperiden Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.. biperiden : A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.	3.23	1	0	piperidines; tertiary alcohol; tertiary amino compound	antidote to sarin poisoning; antidyskinesia agent; antiparkinson drug; muscarinic antagonist; parasympatholytic
bisacodyl Bisacodyl: A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)	3.23	1	0	diarylmethane
bisindolylmaleimide i bisindolylmaleimide I: a bis(indolyl)maleimide	2.89	3	0
bisindolylmaleimide iv [no description available]	2.41	1	0	indoles; maleimides
bisoprolol Bisoprolol: A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.	3.23	1	0	secondary alcohol; secondary amine	anti-arrhythmia drug; antihypertensive agent; beta-adrenergic antagonist; sympatholytic agent
bufexamac Bufexamac: A benzeneacetamide with anti-inflammatory, analgesic, and antipyretic action. It is administered topically, orally, or rectally.. bufexamac : A hydroxamic acid derived from phenylacetamide in which the benzene moiety is substituted at C-4 by a butoxy group. It has anti-inflammatory, analgesic, and antipyretic properties.	2.89	3	0	aromatic ether; hydroxamic acid	antipyretic; non-narcotic analgesic; non-steroidal anti-inflammatory drug
bumetanide [no description available]	3.23	1	0	amino acid; benzoic acids; sulfonamide	diuretic; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
buspirone Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.. buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.	3.23	1	0	azaspiro compound; N-alkylpiperazine; N-arylpiperazine; organic heteropolycyclic compound; piperidones; pyrimidines	anxiolytic drug; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; sedative; serotonergic agonist
busulfan [no description available]	4.41	3	0	methanesulfonate ester	alkylating agent; antineoplastic agent; carcinogenic agent; insect sterilant; teratogenic agent
secbutabarbital secbutabarbital: Butabarbital (a synonym for Secbutabarbital) should be distinguished from Butobarbital	3.23	1	0	barbiturates
cadralazine cadralazine: structure given in first source	2.89	3	0	organic molecular entity
caffeine [no description available]	4.22	2	0	purine alkaloid; trimethylxanthine	adenosine A2A receptor antagonist; adenosine receptor antagonist; adjuvant; central nervous system stimulant; diuretic; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; environmental contaminant; food additive; fungal metabolite; geroprotector; human blood serum metabolite; mouse metabolite; mutagen; plant metabolite; psychotropic drug; ryanodine receptor agonist; xenobiotic
verapamil Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.. verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.. 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.	3.89	3	0	aromatic ether; nitrile; polyether; tertiary amino compound
candesartan cilexetil candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects	3.51	1	0	biphenyls
candesartan candesartan: a nonpeptide angiotensin II receptor antagonist. candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.	3.23	1	0	benzimidazolecarboxylic acid; biphenylyltetrazole	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
carbamazepine Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.. carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.	3.23	1	0	dibenzoazepine; ureas	analgesic; anticonvulsant; antimanic drug; drug allergen; EC 3.5.1.98 (histone deacetylase) inhibitor; environmental contaminant; glutamate transporter activator; mitogen; non-narcotic analgesic; sodium channel blocker; xenobiotic
carbinoxamine carbinoxamine: Note: tradenames that start with Histex refer to more than one drug. carbinoxamine : An organochlorine compound that is 2-(4-chlorobenzyl)pyridine in which one of the benzylic hydrogens is substituted by 2-(dimethylamino)ethoxy group. It is an ethanolamine-type antihistamine, used as its maleate salt for treating hay fever, as well as mild cases of Parkinson's disease.	3.23	1	0	monochlorobenzenes; pyridines; tertiary amino compound	anti-allergic agent; antiparkinson drug; H1-receptor antagonist; muscarinic antagonist
carisoprodol Carisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202). carisoprodol : A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.	3.23	1	0	carbamate ester	muscle relaxant
carvedilol [no description available]	3.98	3	0	carbazoles; secondary alcohol; secondary amino compound	alpha-adrenergic antagonist; antihypertensive agent; beta-adrenergic antagonist; cardiovascular drug; vasodilator agent
celecoxib [no description available]	3.9	3	0	organofluorine compound; pyrazoles; sulfonamide; toluenes	cyclooxygenase 2 inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug
cetirizine Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.. cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.	3.98	3	0	ether; monocarboxylic acid; monochlorobenzenes; piperazines	anti-allergic agent; environmental contaminant; H1-receptor antagonist; xenobiotic
chelerythrine chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.	2.08	1	0	benzophenanthridine alkaloid; organic cation	antibacterial agent; antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor
chlorambucil Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed). chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.	3.59	2	0	aromatic amine; monocarboxylic acid; nitrogen mustard; organochlorine compound; tertiary amino compound	alkylating agent; antineoplastic agent; carcinogenic agent; drug allergen; immunosuppressive agent
chlorcyclizine chlorcyclizine: was heading 1964-94 (Prov 1964-73); CHLOROCYCLIZINE & HISTACHLORAZINE were see CHLORCYCLIZINE 1977-94; use PIPERAZINES to search CHLORCYCLIZINE 1966-94; histamine H1-blocker used both orally and topically in allergies and also for the prevention of motion sickness	4.19	4	0	diarylmethane
chlordiazepoxide Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.. chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.	3.23	1	0	benzodiazepine
chlormezanone Chlormezanone: A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.. chlormezanone : A 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions.	3.23	1	0	1,3-thiazine; lactam; monochlorobenzenes; sulfone	antipsychotic agent; anxiolytic drug; muscle relaxant
chloroquine Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.	3.9	3	0	aminoquinoline; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; autophagy inhibitor; dermatologic drug
chlorothiazide Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812). thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.. chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.	3.23	1	0	benzothiadiazine	antihypertensive agent; diuretic
chlorpheniramine Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.. chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.	3.23	1	0	monochlorobenzenes; pyridines; tertiary amino compound	anti-allergic agent; antidepressant; antipruritic drug; H1-receptor antagonist; histamine antagonist; serotonin uptake inhibitor
chlorpromazine Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.. chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.	3.61	2	0	organochlorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; phenothiazine antipsychotic drug
chlorpropamide Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277). chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.	3.23	1	0	monochlorobenzenes; N-sulfonylurea	hypoglycemic agent; insulin secretagogue
chlorthalidone Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.	3.23	1	0	isoindoles; monochlorobenzenes; sulfonamide
chlorzoxazone Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202). chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.	3.23	1	0	1,3-benzoxazoles; heteroaryl hydroxy compound; organochlorine compound	muscle relaxant; sedative
ci 994 tacedinaline: oral cytostatic drug with impressive differential activity against leukemic cells & normal stem-cells. tacedinaline : A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.	2.89	3	0	acetamides; benzamides; substituted aniline	antineoplastic agent; EC 3.5.1.98 (histone deacetylase) inhibitor
cilostazol [no description available]	3.61	2	0	lactam; tetrazoles	anticoagulant; bronchodilator agent; EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor; fibrin modulating drug; neuroprotective agent; platelet aggregation inhibitor; vasodilator agent
cimetidine Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.. cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.	3.23	1	0	aliphatic sulfide; guanidines; imidazoles; nitrile	adjuvant; analgesic; anti-ulcer drug; H2-receptor antagonist; P450 inhibitor
ciprofloxacin Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.	3.23	1	0	aminoquinoline; cyclopropanes; fluoroquinolone antibiotic; N-arylpiperazine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone; zwitterion	antibacterial drug; antiinfective agent; antimicrobial agent; DNA synthesis inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; environmental contaminant; topoisomerase IV inhibitor; xenobiotic
cisapride Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed). cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.	2.08	1	0	benzamides
citalopram Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.. citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.. 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.	3.23	1	0	2-benzofurans; cyclic ether; nitrile; organofluorine compound; tertiary amino compound
clofazimine Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619). clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.	3.51	1	0	monochlorobenzenes; phenazines	dye; leprostatic drug; non-steroidal anti-inflammatory drug
clofibrate angiokapsul: contains clofibrate & insoitolnicotinate	3.23	1	0	aromatic ether; ethyl ester; monochlorobenzenes	anticholesteremic drug; antilipemic drug; geroprotector; PPARalpha agonist
clomiphene [no description available]	3.23	1	0	tertiary amine	estrogen antagonist; estrogen receptor modulator
clomipramine Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.. clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.	3.23	1	0	dibenzoazepine	anticoronaviral agent; antidepressant; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; serotonergic antagonist; serotonergic drug; serotonin uptake inhibitor
clonazepam Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.. clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.	3.23	1	0	1,4-benzodiazepinone; monochlorobenzenes	anticonvulsant; anxiolytic drug; GABA modulator
clonidine Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.. clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.	3.23	1	0	clonidine; imidazoline
chlorazepate clorazepic acid : A 1,4-benzodiazepinone in which the oxo group is at position 2, and which is substituted at positions 3, 5, and 7 by carboxy, phenyl and chloro groups, respectively.	3.23	1	0	1,4-benzodiazepinone	anticonvulsant; anxiolytic drug; GABA modulator; prodrug
clotrimazole [no description available]	3.23	1	0	conazole antifungal drug; imidazole antifungal drug; imidazoles; monochlorobenzenes	antiinfective agent; environmental contaminant; xenobiotic
cyclobenzaprine cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure. cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.	3.23	1	0	carbotricyclic compound	antidepressant; muscle relaxant; tranquilizing drug
cyclofenil Cyclofenil: A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE.	3.23	1	0	organic molecular entity
cyclosporine cyclosporin A : A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle.	2.59	2	0
cyproheptadine Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.. cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.	3.65	2	0	piperidines; tertiary amine	anti-allergic agent; antipruritic drug; gastrointestinal drug; H1-receptor antagonist; serotonergic antagonist
dapsone [no description available]	3.23	1	0	substituted aniline; sulfone	anti-inflammatory drug; antiinfective agent; antimalarial; leprostatic drug
deferoxamine Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.. desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.	3.23	1	0	acyclic desferrioxamine	bacterial metabolite; ferroptosis inhibitor; iron chelator; siderophore
desipramine Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.. desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.	3.23	1	0	dibenzoazepine; secondary amino compound	adrenergic uptake inhibitor; alpha-adrenergic antagonist; antidepressant; cholinergic antagonist; drug allergen; EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; H1-receptor antagonist; serotonin uptake inhibitor
amphetamine Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.. 1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.. amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.	3.23	1	0	primary amine
diazepam Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.. diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.	3.61	2	0	1,4-benzodiazepinone; organochlorine compound	anticonvulsant; anxiolytic drug; environmental contaminant; sedative; xenobiotic
diazoxide Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.. diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.	3.23	1	0	benzothiadiazine; organochlorine compound; sulfone	antihypertensive agent; beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; diuretic; K-ATP channel agonist; sodium channel blocker; sympathomimetic agent; vasodilator agent
diclofenac Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.. diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.	3.23	1	0	amino acid; aromatic amine; dichlorobenzene; monocarboxylic acid; secondary amino compound	antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
dichlorphenamide Dichlorphenamide: A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.. diclofenamide : A sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma.	3.23	1	0	dichlorobenzene; sulfonamide	antiglaucoma drug; EC 4.2.1.1 (carbonic anhydrase) inhibitor; ophthalmology drug
dicyclomine Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.. dicyclomine : The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.	3.23	1	0	carboxylic ester; tertiary amine	antispasmodic drug; muscarinic antagonist; parasympatholytic
pentetic acid Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.	3.23	1	0	pentacarboxylic acid	copper chelator
diflunisal Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.. diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.	3.23	1	0	monohydroxybenzoic acid; organofluorine compound	non-narcotic analgesic; non-steroidal anti-inflammatory drug
dimercaprol Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.. dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.	3.23	1	0	dithiol; primary alcohol	chelator
diphenhydramine Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.. diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.. antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.	3.23	1	0	ether; tertiary amino compound	anti-allergic agent; antidyskinesia agent; antiemetic; antiparkinson drug; antipruritic drug; antitussive; H1-receptor antagonist; local anaesthetic; muscarinic antagonist; oneirogen; sedative
dipyridamole Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752). dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.	4.22	2	0	piperidines; pyrimidopyrimidine; tertiary amino compound; tetrol	adenosine phosphodiesterase inhibitor; EC 3.5.4.4 (adenosine deaminase) inhibitor; platelet aggregation inhibitor; vasodilator agent
disopyramide Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.. disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.	3.61	2	0	monocarboxylic acid amide; pyridines; tertiary amino compound	anti-arrhythmia drug
disulfiram [no description available]	3.23	1	0	organic disulfide; organosulfur acaricide	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; EC 3.1.1.1 (carboxylesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; ferroptosis inducer; fungicide; NF-kappaB inhibitor
valproic acid Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.. valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.	3.23	1	0	branched-chain fatty acid; branched-chain saturated fatty acid	anticonvulsant; antimanic drug; EC 3.5.1.98 (histone deacetylase) inhibitor; GABA agent; neuroprotective agent; psychotropic drug; teratogenic agent
donepezil Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.. donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.. 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.	3.61	2	0	aromatic ether; indanones; piperidines; racemate	EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; nootropic agent
doxapram Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225). doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.	3.23	1	0	morpholines; pyrrolidin-2-ones	central nervous system stimulant
doxazosin Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.. doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.	3.23	1	0	aromatic amine; benzodioxine; monocarboxylic acid amide; N-acylpiperazine; N-arylpiperazine; quinazolines	alpha-adrenergic antagonist; antihyperplasia drug; antihypertensive agent; antineoplastic agent; vasodilator agent
doxepin Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.. doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.	3.23	1	0	dibenzooxepine; tertiary amino compound	antidepressant
doxylamine Doxylamine: Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.	3.23	1	0	pyridines; tertiary amine	anti-allergic agent; antiemetic; antitussive; cholinergic antagonist; H1-receptor antagonist; histamine antagonist; sedative
droperidol Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593). droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.	3.61	2	0	aromatic ketone; benzimidazoles; organofluorine compound	anaesthesia adjuvant; antiemetic; dopaminergic antagonist; first generation antipsychotic
dyphylline Dyphylline: A THEOPHYLLINE derivative with broncho- and vasodilator properties. It is used in the treatment of asthma, cardiac dyspnea, and bronchitis.. dyphylline : An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs.	3.23	1	0	oxopurine; propane-1,2-diols	bronchodilator agent; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; muscle relaxant; vasodilator agent
edrophonium Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.. edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.	3.23	1	0	phenols; quaternary ammonium ion	antidote; diagnostic agent; EC 3.1.1.8 (cholinesterase) inhibitor
estazolam Estazolam: A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than DIAZEPAM or NITRAZEPAM.. estazolam : A triazolo[4,3-a][1,4]benzodiazepine having a phenyl group at position 6 and a chloro substituent at position 8. A short-acting benzodiazepine with general properties similar to diazepam, it is given by mouth as a hypnotic in the short-term management of insomnia.	3.23	1	0	triazoles; triazolobenzodiazepine	anticonvulsant; anxiolytic drug; GABA modulator
ethacrynic acid Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.. etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.	3.23	1	0	aromatic ether; aromatic ketone; dichlorobenzene; monocarboxylic acid	EC 2.5.1.18 (glutathione transferase) inhibitor; ion transport inhibitor; loop diuretic
ethosuximide Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.. ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.	3.23	1	0	dicarboximide; pyrrolidinone	anticonvulsant; geroprotector; T-type calcium channel blocker
ethotoin ethotoin: was heading 1966-94 (see under HYDANTOINS 1966-90); use HYDANTOINS to search ETHOTOIN 1966-94. ethotoin : An imidazolidine-2,4-dione that is hydantoin substituted by ethyl and phenyl at positions 3 and 5, respectively. An antiepileptic, it is less toxic than phenytoin but also less effective.	3.23	1	0	imidazolidine-2,4-dione	anticonvulsant
etidronate Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.. etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.	3.23	1	0	1,1-bis(phosphonic acid)	antineoplastic agent; bone density conservation agent; chelator
etodolac Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).. etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.	3.23	1	0	monocarboxylic acid; organic heterotricyclic compound	antipyretic; cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
brl 42810 [no description available]	3.23	1	0	2-aminopurines; acetate ester	antiviral drug; prodrug
famotidine Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.	3.47	1	1	1,3-thiazoles; guanidines; sulfonamide	anti-ulcer drug; H2-receptor antagonist; P450 inhibitor
felbamate Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.. felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.	3.23	1	0	carbamate ester	anticonvulsant; neuroprotective agent
felodipine Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.. felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.	3.23	1	0	dichlorobenzene; dihydropyridine; ethyl ester; methyl ester	anti-arrhythmia drug; antihypertensive agent; calcium channel blocker; vasodilator agent
fenbendazole Fenbendazole: Antinematodal benzimidazole used in veterinary medicine.. fenbendazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.	2.89	3	0	aryl sulfide; benzimidazoles; carbamate ester	antinematodal drug
fenofibrate Pharmavit: a polyvitamin product, comprising vitamins A, D2, B1, B2, B6, C, E, nicotinamide, & calcium pantothene; may be a promising agent for application to human populations exposed to carcinogenic and genetic hazards of ionizing radiation; RN from CHEMLINE	4.22	2	0	aromatic ether; chlorobenzophenone; isopropyl ester; monochlorobenzenes	antilipemic drug; environmental contaminant; geroprotector; xenobiotic
fenoldopam Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.	3.23	1	0	benzazepine	alpha-adrenergic agonist; antihypertensive agent; dopamine agonist; dopaminergic antagonist; vasodilator agent
fenoprofen Fenoprofen: A propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.. fenoprofen : A monocarboxylic acid that is propanoic acid in which one of the hydrogens at position 2 is substituted by a 3-phenoxyphenyl group. A non-steroidal anti-inflammatory drug, the dihydrate form of the calcium salt is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.	3.23	1	0	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; non-narcotic analgesic; non-steroidal anti-inflammatory drug
berotek Fenoterol: A synthetic adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.. fenoterol : A member of the class resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction.	2.15	1	0	resorcinols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; sympathomimetic agent; tocolytic agent
fexofenadine fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl. fexofenadine : A piperidine-based anti-histamine compound.	3.23	1	0	piperidines; tertiary amine	anti-allergic agent; H1-receptor antagonist
fipexide fipexide: regulates dopaminergic systems at macromolecular level	3.23	1	0	benzodioxoles
flavoxate Flavoxate: A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist.. flavoxate : A carboxylic ester resulting from the formal condensation of 3-methylflavone-8-carboxylic acid with 2-(1-piperidinyl)ethanol.	3.23	1	0	carboxylic ester; flavones; piperidines; tertiary amino compound	antispasmodic drug; muscarinic antagonist; parasympatholytic
flecainide Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.. flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).	3.61	2	0	aromatic ether; monocarboxylic acid amide; organofluorine compound; piperidines	anti-arrhythmia drug
fluconazole Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.. fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.	3.66	2	0	conazole antifungal drug; difluorobenzene; tertiary alcohol; triazole antifungal drug	environmental contaminant; P450 inhibitor; xenobiotic
flucytosine Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.. flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.	3.23	1	0	aminopyrimidine; nucleoside analogue; organofluorine compound; pyrimidine antifungal drug; pyrimidone	prodrug
fluphenazine [no description available]	3.23	1	0	N-alkylpiperazine; organofluorine compound; phenothiazines	anticoronaviral agent; dopaminergic antagonist; phenothiazine antipsychotic drug
flumazenil Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.. flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.	3.23	1	0	ethyl ester; imidazobenzodiazepine; organofluorine compound	antidote to benzodiazepine poisoning; GABA antagonist
fluorescite fluorescein (acid form) : A xanthene dye that is highly fluorescent and commonly used as a fluorescent tracer.	3.23	1	0	benzoic acids; cyclic ketone; hydroxy monocarboxylic acid; organic heterotricyclic compound; phenols; xanthene dye	fluorescent dye; radioopaque medium
fluorouracil Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.	3.58	2	0	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
fluoxetine Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.. fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.. N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.	3.23	1	0	(trifluoromethyl)benzenes; aromatic ether; secondary amino compound
flurazepam Flurazepam: A benzodiazepine derivative used mainly as a hypnotic.. flurazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.	3.23	1	0	1,4-benzodiazepinone; monofluorobenzenes; organochlorine compound; tertiary amino compound	anticonvulsant; anxiolytic drug; GABAA receptor agonist; sedative
flurbiprofen Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.. flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.	3.23	1	0	fluorobiphenyl; monocarboxylic acid	antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
flutamide Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.	3.23	1	0	(trifluoromethyl)benzenes; monocarboxylic acid amide	androgen antagonist; antineoplastic agent
fomepizole Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.. fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.	3.23	1	0	pyrazoles	antidote; EC 1.1.1.1 (alcohol dehydrogenase) inhibitor; protective agent
foscarnet Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.. phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.	3.23	1	0	carboxylic acid; one-carbon compound; phosphonic acids	antiviral drug; geroprotector; HIV-1 reverse transcriptase inhibitor; sodium-dependent Pi-transporter inhibitor
furosemide Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.. furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.	4.45	3	0	chlorobenzoic acid; furans; sulfonamide	environmental contaminant; loop diuretic; xenobiotic
gabapentin Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.. gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.	3.23	1	0	gamma-amino acid	anticonvulsant; calcium channel blocker; environmental contaminant; xenobiotic
gemfibrozil [no description available]	3.23	1	0	aromatic ether	antilipemic drug
glafenine Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.. glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.	3.23	1	0	aminoquinoline; carboxylic ester; glycol; organochlorine compound; secondary amino compound	inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
glimepiride glimepiride: structure given in first source	3.23	1	0	sulfonamide
glipizide Glipizide: An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.. glipizide : An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.	3.68	2	0	aromatic amide; monocarboxylic acid amide; N-sulfonylurea; pyrazines	EC 2.7.1.33 (pantothenate kinase) inhibitor; hypoglycemic agent; insulin secretagogue
glyburide Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide. glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.	4.52	3	0	monochlorobenzenes; N-sulfonylurea	anti-arrhythmia drug; EC 2.7.1.33 (pantothenate kinase) inhibitor; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor; hypoglycemic agent
2-cyclopentyl-2-hydroxy-2-phenylacetic acid (1,1-dimethyl-3-pyrrolidin-1-iumyl) ester [no description available]	3.23	1	0	benzenes
go 6976 [no description available]	2.89	3	0	indolocarbazole; organic heterohexacyclic compound	EC 2.7.11.13 (protein kinase C) inhibitor
gossypol Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.	2.46	2	0
granisetron [no description available]	3.23	1	0	aromatic amide; indazoles
guaifenesin Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.	3.23	1	0	methoxybenzenes
guanethidine Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.. guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.. guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.	3.23	1	0	azocanes; guanidines	adrenergic antagonist; antihypertensive agent; sympatholytic agent
guanfacine Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.	3.23	1	0	acetamides
guanidine Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.. guanidine : An aminocarboxamidine, the parent compound of the guanidines.	3.23	1	0	carboxamidine; guanidines; one-carbon compound
fasudil fasudil: intracellular calcium antagonist; structure in first source. fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.	2.52	2	0	isoquinolines; N-sulfonyldiazepane	antihypertensive agent; calcium channel blocker; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; geroprotector; neuroprotective agent; nootropic agent; vasodilator agent
haloperidol Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279). haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.	4.35	5	0	aromatic ketone; hydroxypiperidine; monochlorobenzenes; organofluorine compound; tertiary alcohol	antidyskinesia agent; antiemetic; dopaminergic antagonist; first generation antipsychotic; serotonergic antagonist
homochlorocyclizine homochlorocyclizine: RN given refers to parent cpd	2.89	3	0	diarylmethane
hydralazine Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.. hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.	3.23	1	0	azaarene; hydrazines; ortho-fused heteroarene; phthalazines	antihypertensive agent; vasodilator agent
hydrochlorothiazide Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.. hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.	3.23	1	0	benzothiadiazine; organochlorine compound; sulfonamide	antihypertensive agent; diuretic; environmental contaminant; xenobiotic
hydroflumethiazide Hydroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822). hydroflumethiazide : A benzothiadiazine consisting of a 3,4-dihydro-HH-1,2,4-benzothiadiazine bicyclic system dioxygenated on sulfur and carrying trifluoromethyl and aminosulfonyl groups at positions 6 and 7 respectively. A diuretic with actions and uses similar to those of hydrochlorothiazide.	3.23	1	0	benzothiadiazine; thiazide	antihypertensive agent; diuretic
hydroxychloroquine Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970). hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.	3.23	1	0	aminoquinoline; organochlorine compound; primary alcohol; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; dermatologic drug
hydroxyurea [no description available]	5.93	12	0	one-carbon compound; ureas	antimetabolite; antimitotic; antineoplastic agent; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; genotoxin; immunomodulator; radical scavenger; teratogenic agent
hydroxyzine Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.. hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.	4.19	4	0	hydroxyether; monochlorobenzenes; N-alkylpiperazine	anticoronaviral agent; antipruritic drug; anxiolytic drug; dermatologic drug; H1-receptor antagonist
ibuprofen Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine	3.23	1	0	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; radical scavenger; xenobiotic
phenelzine Phenelzine: One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.	3.23	1	0	primary amine
lidocaine Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.. lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.	3.23	1	0	benzenes; monocarboxylic acid amide; tertiary amino compound	anti-arrhythmia drug; drug allergen; environmental contaminant; local anaesthetic; xenobiotic
ifenprodil ifenprodil: NMDA receptor antagonist	2.89	3	0	piperidines
ifosfamide [no description available]	3.23	1	0	ifosfamides	alkylating agent; antineoplastic agent; environmental contaminant; immunosuppressive agent; xenobiotic
imipramine Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.. imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.	3.23	1	0	dibenzoazepine	adrenergic uptake inhibitor; antidepressant; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
amrinone Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.. amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.	3.23	1	0	bipyridines	EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
indapamide Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.. indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.	3.23	1	0	indoles; organochlorine compound; sulfonamide	antihypertensive agent; diuretic
indirubin-3'-monoxime indirubin-3'-monoxime: has antiangiogenic activity. indirubin-3'-monoxime : A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.	2.08	1	0
indomethacin Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.. indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.	3.62	2	0	aromatic ether; indole-3-acetic acids; monochlorobenzenes; N-acylindole	analgesic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; gout suppressant; non-steroidal anti-inflammatory drug; xenobiotic metabolite; xenobiotic
ioversol [no description available]	3.23	1	0	amidobenzoic acid
iproniazid [no description available]	3.23	1	0	carbohydrazide; pyridines
avapro Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.. irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.	3.23	1	0	azaspiro compound; biphenylyltetrazole	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
isocarboxazid Isocarboxazid: An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)	3.23	1	0	benzenes
isoniazid Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.. hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).	3.23	1	0	carbohydrazide	antitubercular agent; drug allergen
isoproterenol Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.. isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.	3.23	1	0	catechols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; sympathomimetic agent
isoxsuprine Isoxsuprine: A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.	3.23	1	0	alkylbenzene
isradipine Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.	3.66	2	0	benzoxadiazole; dihydropyridine; isopropyl ester; methyl ester
itraconazole [no description available]	4.22	2	0	piperazines
4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline WHI P131: a quinazoline derivative, inhibitor of glioblastoma cell adhesion and migration	2.15	1	0
1-(2-naphthalenyl)-3-[(phenylmethyl)-propan-2-ylamino]-1-propanone ZM39923: structure in first source	2.89	3	0	naphthalenes
ketamine Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.. ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.	4.19	4	0	cyclohexanones; monochlorobenzenes; secondary amino compound	analgesic; environmental contaminant; intravenous anaesthetic; neurotoxin; NMDA receptor antagonist; xenobiotic
ketoconazole 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.	5.27	3	1	dichlorobenzene; dioxolane; ether; imidazoles; N-acylpiperazine; N-arylpiperazine
ketoprofen Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.. ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.	4.19	4	0	benzophenones; oxo monocarboxylic acid	antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-steroidal anti-inflammatory drug; xenobiotic
ketorolac Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed). ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.. 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.	3.23	1	0	amino acid; aromatic ketone; monocarboxylic acid; pyrrolizines; racemate	analgesic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
labetalol Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.. labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.. 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.	3.23	1	0	benzamides; benzenes; phenols; primary carboxamide; salicylamides; secondary alcohol; secondary amino compound
lamotrigine [no description available]	3.23	1	0	1,2,4-triazines; dichlorobenzene; primary arylamine	anticonvulsant; antidepressant; antimanic drug; calcium channel blocker; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; excitatory amino acid antagonist; geroprotector; non-narcotic analgesic; xenobiotic
lansoprazole Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.	4.22	2	0	benzimidazoles; pyridines; sulfoxide	anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
leflunomide Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.. leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.	3.94	3	0	(trifluoromethyl)benzenes; isoxazoles; monocarboxylic acid amide	antineoplastic agent; antiparasitic agent; EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; hepatotoxic agent; immunosuppressive agent; non-steroidal anti-inflammatory drug; prodrug; pyrimidine synthesis inhibitor; tyrosine kinase inhibitor
letrozole [no description available]	3.61	2	0	nitrile; triazoles	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
lg 100268 LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source	2.08	1	0
lomefloxacin lomefloxacin: structure given in first source. lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.	3.23	1	0	fluoroquinolone antibiotic; N-arylpiperazine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone	antimicrobial agent; antitubercular agent; photosensitizing agent
lomustine [no description available]	3.23	1	0	N-nitrosoureas; organochlorine compound	alkylating agent; antineoplastic agent
loperamide Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.. loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.	3.23	1	0	monocarboxylic acid amide; monochlorobenzenes; piperidines; tertiary alcohol	anticoronaviral agent; antidiarrhoeal drug; mu-opioid receptor agonist
loratadine Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.. loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.	3.61	2	0	benzocycloheptapyridine; ethyl ester; N-acylpiperidine; organochlorine compound; tertiary carboxamide	anti-allergic agent; cholinergic antagonist; geroprotector; H1-receptor antagonist
lorazepam Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.	3.23	1	0	benzodiazepine
losartan Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.. losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position	4.52	3	0	biphenylyltetrazole; imidazoles	angiotensin receptor antagonist; anti-arrhythmia drug; antihypertensive agent; endothelin receptor antagonist
loxapine Loxapine: An antipsychotic agent used in SCHIZOPHRENIA.	3.23	1	0	dibenzooxazepine	antipsychotic agent; dopaminergic antagonist
ly 303511 LY 303511: inhibitor of phosphatidylinositol 3-kinase	3.25	1	0	N-arylpiperazine
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source	4.76	4	0	chromones; morpholines; organochlorine compound	autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector
maprotiline Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.	3.23	1	0	anthracenes
mebendazole Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.. mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.	4.9	5	0	aromatic ketone; benzimidazoles; carbamate ester	antinematodal drug; microtubule-destabilising agent; tubulin modulator
mecamylamine Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.	3.23	1	0	primary aliphatic amine
mechlorethamine nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.	3.23	1	0	nitrogen mustard; organochlorine compound	alkylating agent
meclizine Meclizine: A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.	3.23	1	0	diarylmethane
meclofenamic acid Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.. meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.	3.23	1	0	aminobenzoic acid; organochlorine compound; secondary amino compound	analgesic; anticonvulsant; antineoplastic agent; antipyretic; antirheumatic drug; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-steroidal anti-inflammatory drug
mefenamic acid Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.. mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.	3.23	1	0	aminobenzoic acid; secondary amino compound	analgesic; antipyretic; antirheumatic drug; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-steroidal anti-inflammatory drug; xenobiotic
memantine [no description available]	3.23	1	0	adamantanes; primary aliphatic amine	antidepressant; antiparkinson drug; dopaminergic agent; neuroprotective agent; NMDA receptor antagonist
mepenzolate mepenzolic acid: anticholinergic, antispasmodic agent; RN given refers to parent cpd; structure	3.23	1	0	diarylmethane
meperidine Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.. pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.	3.23	1	0	ethyl ester; piperidinecarboxylate ester; tertiary amino compound	antispasmodic drug; kappa-opioid receptor agonist; mu-opioid receptor agonist; opioid analgesic
mephenesin Mephenesin: A centrally acting muscle relaxant with a short duration of action.. 1-(2-methylphenyl)glycerol : A glycerol ether in which a single 2-methylphenyl group is attached at position 1 of glycerol via an ether linkage.	2.89	3	0	aromatic ether; glycerol ether
mephenytoin Mephenytoin: An anticonvulsant effective in tonic-clonic epilepsy (EPILEPSY, TONIC-CLONIC). It may cause blood dyscrasias.. mephenytoin : An imidazolidine-2,4-dione (hydantoin) in which the imidazolidine nucleus carries a methyl group at N-3 and has ethyl and phenyl substituents at C-5. An anticonvulsant, it is no longer available in the USA or the UK but is still studied largely because of its interesting hydroxylation polymorphism.	3.23	1	0	imidazolidine-2,4-dione	anticonvulsant
mepivacaine Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168). mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.	3.23	1	0	piperidinecarboxamide	drug allergen; local anaesthetic
meprobamate Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)	3.23	1	0	organic molecular entity
mesalamine Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed). mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.	3.23	1	0	amino acid; aromatic amine; monocarboxylic acid; monohydroxybenzoic acid; phenols	non-steroidal anti-inflammatory drug
mesoridazine Mesoridazine: A phenothiazine antipsychotic with effects similar to CHLORPROMAZINE.. mesoridazine : A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group.	3.23	1	0	phenothiazines; sulfoxide; tertiary amino compound	dopaminergic antagonist; first generation antipsychotic
metaproterenol Metaproterenol: A beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.. orciprenaline : A racemate composed of equimolar amounts of (R)- and (S)-orciprenaline. Used (as its sulfate salt) to relax the airway muscles and improve breathing for patients suffering from asthma or bronchitis.. 5-[1-hydroxy-2-(isopropanylamino)ethyl]benzene-1,3-diol : A member of the class of resorcinols bearing an additional 1-hydroxy-2-(isopropanylamino)ethyl substituent at position 5 of resorcinol itself.	3.23	1	0	aralkylamino compound; phenylethanolamines; resorcinols; secondary alcohol; secondary amino compound
metformin Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289). metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.	3.93	3	0	guanidines	environmental contaminant; geroprotector; hypoglycemic agent; xenobiotic
methadone Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3). methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.. 6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.	3.61	2	0	benzenes; diarylmethane; ketone; tertiary amino compound
methazolamide Methazolamide: A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.	3.23	1	0	sulfonamide; thiadiazoles
methocarbamol Methocarbamol: A centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1206). methocarbamol : A racemate comprising equimolar amounts of (R)- and (S)-methocarbamol. A centrally acting skeletal muscle relaxant, it is used as an adjunct in the short-term symptomatic treatment of painful muscle spasm. The (R)-enantiomer is more active than the (S)-enantiomer.. 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate : A carbamate ester that is glycerol in which one of the primary alcohol groups has been converted to its 2-methoxyphenyl ether while the other has been converted to the corresponding carbamate ester.	3.23	1	0	aromatic ether; carbamate ester; secondary alcohol
methoxsalen Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.. methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.	3.23	1	0	aromatic ether; psoralens	antineoplastic agent; cross-linking reagent; dermatologic drug; photosensitizing agent; plant metabolite
methyclothiazide Methyclothiazide: A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)	3.23	1	0	benzothiadiazine
methylphenidate Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.. methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.. methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.	3.23	1	0	beta-amino acid ester; methyl ester; piperidines
metoclopramide Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.. metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.	3.23	1	0	benzamides; monochlorobenzenes; substituted aniline; tertiary amino compound	antiemetic; dopaminergic antagonist; environmental contaminant; gastrointestinal drug; xenobiotic
metolazone Metolazone: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.. metolazone : A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.	3.23	1	0	organochlorine compound; quinazolines; sulfonamide	antihypertensive agent; diuretic; ion transport inhibitor
metoprolol Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.. metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.	3.23	1	0	aromatic ether; propanolamine; secondary alcohol; secondary amino compound	antihypertensive agent; beta-adrenergic antagonist; environmental contaminant; geroprotector; xenobiotic
metronidazole Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.. metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.	3.61	2	0	C-nitro compound; imidazoles; primary alcohol	antiamoebic agent; antibacterial drug; antimicrobial agent; antiparasitic agent; antitrichomonal drug; environmental contaminant; prodrug; radiosensitizing agent; xenobiotic
metyrapone Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.. metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.	3.23	1	0	aromatic ketone	antimetabolite; diagnostic agent; EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
mexiletine Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.. mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.	3.23	1	0	aromatic ether; primary amino compound	anti-arrhythmia drug
midazolam Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.. midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.	5.01	2	1	imidazobenzodiazepine; monofluorobenzenes; organochlorine compound	anticonvulsant; antineoplastic agent; anxiolytic drug; apoptosis inducer; central nervous system depressant; GABAA receptor agonist; general anaesthetic; muscle relaxant; sedative
midodrine Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.. midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.	3.23	1	0	amino acid amide; aromatic ether; secondary alcohol	alpha-adrenergic agonist; prodrug; sympathomimetic agent; vasoconstrictor agent
milrinone [no description available]	3.23	1	0	bipyridines; nitrile; pyridone	cardiotonic drug; EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor; platelet aggregation inhibitor; vasodilator agent
minoxidil Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371). minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.	3.23	1	0	dialkylarylamine; tertiary amino compound
mirtazapine Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.	3.23	1	0	benzazepine; tetracyclic antidepressant	alpha-adrenergic antagonist; anxiolytic drug; H1-receptor antagonist; histamine antagonist; oneirogen; serotonergic antagonist
mitotane Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.	3.23	1	0	diarylmethane
mitoxantrone Mitoxantrone: An anthracenedione-derived antineoplastic agent.. mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.	4.32	5	0	dihydroxyanthraquinone	analgesic; antineoplastic agent
modafinil Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.. modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.. 2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.	3.23	1	0	monocarboxylic acid amide; sulfoxide
moxisylyte Moxisylyte: An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)	3.23	1	0	monoterpenoid
entinostat [no description available]	2.08	1	0	benzamides; carbamate ester; primary amino compound; pyridines; substituted aniline	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
nabumetone Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.. nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.	3.23	1	0	methoxynaphthalene; methyl ketone	cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug
nadolol [no description available]	3.23	1	0	tetralins
nalidixic acid [no description available]	3.23	1	0	1,8-naphthyridine derivative; monocarboxylic acid; quinolone antibiotic	antibacterial drug; antimicrobial agent; DNA synthesis inhibitor
naratriptan naratriptan: structure given in first source	3.23	1	0	heteroarylpiperidine; sulfonamide; tryptamines	serotonergic agonist; vasoconstrictor agent
nefazodone nefazodone: may be useful as an opiate adjunct	3.23	1	0	aromatic ether; monochlorobenzenes; N-alkylpiperazine; N-arylpiperazine; triazoles	alpha-adrenergic antagonist; analgesic; antidepressant; serotonergic antagonist; serotonin uptake inhibitor
nevirapine Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.. nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.	3.23	1	0	cyclopropanes; dipyridodiazepine	antiviral drug; HIV-1 reverse transcriptase inhibitor
nialamide Nialamide: An MAO inhibitor that is used as an antidepressive agent.	3.23	1	0	organonitrogen compound; organooxygen compound
nicardipine Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.. nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.. 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.	4.22	2	0	benzenes; C-nitro compound; diester; dihydropyridine; methyl ester; tertiary amino compound
niclosamide Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48). niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.	2.89	3	0	benzamides; C-nitro compound; monochlorobenzenes; salicylanilides; secondary carboxamide	anthelminthic drug; anticoronaviral agent; antiparasitic agent; apoptosis inducer; molluscicide; piscicide; STAT3 inhibitor
nifedipine Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.	4.45	3	0	C-nitro compound; dihydropyridine; methyl ester	calcium channel blocker; human metabolite; tocolytic agent; vasodilator agent
nilutamide [no description available]	3.23	1	0	(trifluoromethyl)benzenes; C-nitro compound; imidazolidinone	androgen antagonist; antineoplastic agent
nimesulide nimesulide: structure. nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.	3.23	1	0	aromatic ether; C-nitro compound; sulfonamide	cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
nimodipine Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.. nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.	4.22	2	0	2-methoxyethyl ester; C-nitro compound; dicarboxylic acids and O-substituted derivatives; diester; dihydropyridine; isopropyl ester	antihypertensive agent; calcium channel blocker; cardiovascular drug; vasodilator agent
nisoldipine Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.. nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.. methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.	3.23	1	0	C-nitro compound; dicarboxylic acids and O-substituted derivatives; diester; dihydropyridine; methyl ester
nitrendipine Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.. nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.	3.66	2	0	C-nitro compound; dicarboxylic acids and O-substituted derivatives; diester; dihydropyridine; ethyl ester; methyl ester	antihypertensive agent; calcium channel blocker; geroprotector; vasodilator agent
nitroglycerin Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.. nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.. nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.	3.23	1	0	nitroglycerol	explosive; muscle relaxant; nitric oxide donor; prodrug; tocolytic agent; vasodilator agent; xenobiotic
nizatidine [no description available]	3.23	1	0	1,3-thiazoles; C-nitro compound; carboxamidine; organic sulfide; tertiary amino compound	anti-ulcer drug; cholinergic drug; H2-receptor antagonist
nomifensine Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266). nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.	3.23	1	0	isoquinolines	dopamine uptake inhibitor
norfloxacin Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.. norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.	3.23	1	0	fluoroquinolone antibiotic; N-arylpiperazine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone	antibacterial drug; DNA synthesis inhibitor; environmental contaminant; xenobiotic
nortriptyline Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.. nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.	3.23	1	0	organic tricyclic compound; secondary amine	adrenergic uptake inhibitor; analgesic; antidepressant; antineoplastic agent; apoptosis inducer; drug metabolite
ofloxacin Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.. 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.. ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.	3.23	1	0	3-oxo monocarboxylic acid; N-arylpiperazine; N-methylpiperazine; organofluorine compound; oxazinoquinoline
olomoucine olomoucine: inhibits protein P34CDC2. olomoucine : A 9H-purine that is substituted by a (2-hydroxyethyl)nitrilo, benzylnitrilo and a methyl group at positions 2,6 and 9, respectively. It is a cyclin-dependent kinase inhibitor.	2.41	1	0	2,6-diaminopurines; ethanolamines	EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
olprinone olprinone: RN refers to HCl; structure given in first source	2.08	1	0	bipyridines
omeprazole Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.. omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.. 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.	4.45	3	0	aromatic ether; benzimidazoles; pyridines; sulfoxide
ondansetron Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.	3.23	1	0	carbazoles
orphenadrine Orphenadrine: A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.. orphenadrine : A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.	3.23	1	0	ether; tertiary amino compound	antidyskinesia agent; antiparkinson drug; H1-receptor antagonist; muscarinic antagonist; muscle relaxant; NMDA receptor antagonist; parasympatholytic
oxaprozin Oxaprozin: An oxazole-propionic acid derivative, cyclooxygenase inhibitor, and non-steroidal anti-inflammatory drug that is used in the treatment of pain and inflammation associated with of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; and ARTHRITIS, JUVENILE.. oxaprozin : A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis.	3.23	1	0	1,3-oxazoles; monocarboxylic acid	analgesic; non-steroidal anti-inflammatory drug
oxazepam Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.. oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.	3.23	1	0	1,4-benzodiazepinone; organochlorine compound	anxiolytic drug; environmental contaminant; xenobiotic
oxibendazole oxibendazole: structure	2.89	3	0	benzimidazoles; carbamate ester
oxybutynin oxybutynin: RN given refers to parent cpd. oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.	3.23	1	0	acetylenic compound; carboxylic ester; racemate; tertiary alcohol; tertiary amino compound	antispasmodic drug; calcium channel blocker; local anaesthetic; muscarinic antagonist; muscle relaxant; parasympatholytic
aminosalicylic acid Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.. 4-aminosalicylic acid : An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.	3.23	1	0	aminobenzoic acid; phenols	antitubercular agent
4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine: a 5-HT(1A) ligand; structure in first source	2.89	3	0
pamidronate [no description available]	3.23	1	0	phosphonoacetic acid
pantoprazole Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.. pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.	4.22	2	0	aromatic ether; benzimidazoles; organofluorine compound; pyridines; sulfoxide	anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; environmental contaminant; xenobiotic
papaverine Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.. papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.	4.22	2	0	benzylisoquinoline alkaloid; dimethoxybenzene; isoquinolines	antispasmodic drug; vasodilator agent
pd 98059 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source. 2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.	2.17	1	0	aromatic amine; monomethoxyflavone	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector
pemoline Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.. pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.	3.23	1	0	1,3-oxazoles	central nervous system stimulant
pentamidine Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.. pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.	3.23	1	0	aromatic ether; carboxamidine; diether	anti-inflammatory agent; antifungal agent; calmodulin antagonist; chemokine receptor 5 antagonist; EC 2.3.1.48 (histone acetyltransferase) inhibitor; NMDA receptor antagonist; S100 calcium-binding protein B inhibitor; trypanocidal drug; xenobiotic
pentobarbital Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236). pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.	3.61	2	0	barbiturates	GABAA receptor agonist
pentoxifylline [no description available]	3.64	2	0	oxopurine
perhexiline Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.	3.23	1	0	piperidines	cardiovascular drug
perphenazine Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.. perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.	4.19	4	0	N-(2-hydroxyethyl)piperazine; N-alkylpiperazine; organochlorine compound; phenothiazines	antiemetic; dopaminergic antagonist; phenothiazine antipsychotic drug
phenobarbital Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.. phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.	3.23	1	0	barbiturates	anticonvulsant; drug allergen; excitatory amino acid antagonist; sedative
phenoxybenzamine Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.	3.23	1	0	aromatic amine
phentermine Phentermine: A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.	3.23	1	0	primary amine	adrenergic agent; appetite depressant; central nervous system drug; central nervous system stimulant; dopaminergic agent; sympathomimetic agent
4-phenylbutyric acid 4-phenylbutyric acid: RN refers to the parent cpd. 4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.	3.23	1	0	monocarboxylic acid	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor; prodrug
pimobendan pimobendan: produces arterial & venous dilatation in dogs; structure given in first source	2.89	3	0	benzimidazoles; pyridazinone	cardiotonic drug; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent
pindolol Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638). pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.	3.23	1	0	indoles; secondary amine	antiglaucoma drug; antihypertensive agent; beta-adrenergic antagonist; serotonergic antagonist; vasodilator agent
pioglitazone Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.. pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.	3.61	2	0	aromatic ether; pyridines; thiazolidinediones	antidepressant; cardioprotective agent; EC 2.7.1.33 (pantothenate kinase) inhibitor; EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; geroprotector; hypoglycemic agent; insulin-sensitizing drug; PPARgamma agonist; xenobiotic
polythiazide [no description available]	3.23	1	0	benzothiadiazine
ag 1879 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor	2.89	3	0	aromatic amine; monochlorobenzenes; pyrazolopyrimidine	beta-adrenergic antagonist; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector
duodote duodote: consists of atropine and pralidoxime chloride; for treating those exposed to organophosphorus-containing nerve agents	3.23	1	0	pyridinium ion	antidote to organophosphate poisoning; antidote to sarin poisoning; cholinergic drug; cholinesterase reactivator
praziquantel azinox: Russian drug	3.23	1	0	isoquinolines
prazosin Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.. prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.	4.11	4	0	aromatic ether; furans; monocarboxylic acid amide; piperazines; quinazolines	alpha-adrenergic antagonist; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
primaquine Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404). primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.	3.23	1	0	aminoquinoline; aromatic ether; N-substituted diamine	antimalarial
primidone Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.. primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.	3.23	1	0	pyrimidone	anticonvulsant; environmental contaminant; xenobiotic
probenecid Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.. probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.	3.23	1	0	benzoic acids; sulfonamide	uricosuric drug
procainamide Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.. procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.	3.61	2	0	benzamides	anti-arrhythmia drug; platelet aggregation inhibitor; sodium channel blocker
procarbazine Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.. procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.	3.23	1	0	benzamides; hydrazines	antineoplastic agent
prochlorperazine Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612). prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.	3.23	1	0	N-alkylpiperazine; N-methylpiperazine; organochlorine compound; phenothiazines	alpha-adrenergic antagonist; antiemetic; cholinergic antagonist; dopamine receptor D2 antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; first generation antipsychotic
procyclidine Procyclidine: A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.. procyclidine : A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.	3.23	1	0	pyrrolidines; tertiary alcohol	antidyskinesia agent; antiparkinson drug; muscarinic antagonist
promethazine Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.. promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.	3.23	1	0	phenothiazines; tertiary amine	anti-allergic agent; anticoronaviral agent; antiemetic; antipruritic drug; H1-receptor antagonist; local anaesthetic; sedative
propafenone Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.. propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.	3.23	1	0	aromatic ketone; secondary alcohol; secondary amino compound	anti-arrhythmia drug
propantheline Propantheline: A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.	3.23	1	0	xanthenes
propofol Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.. propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.	3.23	1	0	phenols	anticonvulsant; antiemetic; intravenous anaesthetic; radical scavenger; sedative
propranolol Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.. propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.	3.23	1	0	naphthalenes; propanolamine; secondary amine	anti-arrhythmia drug; antihypertensive agent; anxiolytic drug; beta-adrenergic antagonist; environmental contaminant; human blood serum metabolite; vasodilator agent; xenobiotic
protriptyline Protriptyline: Tricyclic antidepressant similar in action and side effects to IMIPRAMINE. It may produce excitation.	3.23	1	0	carbotricyclic compound	antidepressant
pyridostigmine [no description available]	3.23	1	0	pyridinium ion
pyrimethamine Maloprim: contains above 2 cpds	3.68	2	0	aminopyrimidine; monochlorobenzenes	antimalarial; antiprotozoal drug; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
sch 16134 quazepam: structure given in first source	3.23	1	0	benzodiazepine
quetiapine [no description available]	3.23	1	0	dibenzothiazepine; N-alkylpiperazine; N-arylpiperazine	adrenergic antagonist; dopaminergic antagonist; histamine antagonist; second generation antipsychotic; serotonergic antagonist
rabeprazole Rabeprazole: A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.	4.22	2	0	benzimidazoles; pyridines; sulfoxide	anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one [no description available]	2.83	3	0	indoles
raloxifene raloxifene : A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogens at positions 2, 3, and 6 have been replaced by p-hydroxyphenyl, p-[2-(piperidin-1-yl)ethoxy]benzoyl, and hydroxy groups, respectively.	3.23	1	0	1-benzothiophenes; aromatic ketone; N-oxyethylpiperidine; phenols	bone density conservation agent; estrogen antagonist; estrogen receptor modulator
riluzole Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.	3.61	2	0	benzothiazoles
rimantadine Rimantadine: An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.	3.23	1	0	alkylamine
risperidone Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.. risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.	3.61	2	0	1,2-benzoxazoles; heteroarylpiperidine; organofluorine compound; pyridopyrimidine	alpha-adrenergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; H1-receptor antagonist; psychotropic drug; second generation antipsychotic; serotonergic antagonist
rizatriptan rizatriptan: structure given in first source; RN given refers to benzoate	3.23	1	0	tryptamines	anti-inflammatory drug; serotonergic agonist; vasoconstrictor agent
ro 31-8220 Ro 31-8220: a protein kinase C inhibitor	2.89	3	0	imidothiocarbamic ester; indoles; maleimides	EC 2.7.11.13 (protein kinase C) inhibitor
ropinirole [no description available]	4.19	4	0	indolones; tertiary amine	antidyskinesia agent; antiparkinson drug; central nervous system drug; dopamine agonist
salicylsalicylic acid salicylsalicylic acid: structure. salsalate : A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.	3.23	1	0	benzoate ester; benzoic acids; phenols; salicylates	antineoplastic agent; antirheumatic drug; EC 3.5.2.6 (beta-lactamase) inhibitor; hypoglycemic agent; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug
sb 206553 SB 206553: a high-affinity 5-HT(2C/2B) antagonist; structure given in first source	2.08	1	0	pyrroloindole
sb 220025 SB 220025: inhibits p38 mitogen-activated protein kinase; structure in first source. SB220025 : Am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively.	2.08	1	0	aminopyrimidine; imidazoles; organofluorine compound; piperidines	angiogenesis inhibitor; anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sb 239063 SB 239063: structure in first source. SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.	2.04	1	0	imidazoles
sb 202190 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase	3.61	2	0	imidazoles; organofluorine compound; phenols; pyridines	apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
secobarbital Secobarbital: A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.. secobarbital : A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.	3.23	1	0	barbiturates	anaesthesia adjuvant; GABA modulator; sedative
sibutramine sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride	3.23	1	0	organochlorine compound; tertiary amino compound	anti-obesity agent; serotonin uptake inhibitor
sulfadiazine Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.. sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.. diazine : The parent structure of the diazines.	3.23	1	0	pyrimidines; substituted aniline; sulfonamide antibiotic; sulfonamide	antiinfective agent; antimicrobial agent; antiprotozoal drug; coccidiostat; drug allergen; EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor; EC 2.5.1.15 (dihydropteroate synthase) inhibitor; environmental contaminant; xenobiotic
sk&f 86002 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole: inhibits p38 MAP kinase	2.08	1	0	imidazoles
risedronic acid Risedronic Acid: A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.	3.23	1	0	pyridines
sotalol Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.. sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.	3.61	2	0	ethanolamines; secondary alcohol; secondary amino compound; sulfonamide	anti-arrhythmia drug; beta-adrenergic antagonist; environmental contaminant; xenobiotic
imatinib [no description available]	7.56	30	0	aromatic amine; benzamides; N-methylpiperazine; pyridines; pyrimidines	antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
vorinostat Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.. vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).	4.35	5	0	dicarboxylic acid diamide; hydroxamic acid	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
succinylcholine Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.. succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.	3.23	1	0	quaternary ammonium ion; succinate ester	drug allergen; muscle relaxant; neuromuscular agent
sulfamethizole Sulfamethizole: A sulfathiazole antibacterial agent.. sulfamethizole : A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2.	3.23	1	0	sulfonamide antibiotic; sulfonamide; thiadiazoles	antiinfective agent; antimicrobial agent; drug allergen; EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfasalazine Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907). sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.	4.45	3	0
sulfathiazole Sulfathiazole: A sulfathiazole compound that is used as a short-acting anti-infective agent. It is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine.. sulfathiazole : A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position.	3.23	1	0	1,3-thiazoles; substituted aniline; sulfonamide antibiotic; sulfonamide	antiinfective agent; drug allergen; EC 2.5.1.15 (dihydropteroate synthase) inhibitor; environmental contaminant; xenobiotic
2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol [no description available]	3.23	1	0	alkylbenzene
sumatriptan Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.. sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.	3.23	1	0	sulfonamide; tryptamines	serotonergic agonist; vasoconstrictor agent
2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine [no description available]	2.08	1	0	stilbenoid
temazepam Temazepam: A benzodiazepine that acts as a GAMMA-AMINOBUTYRIC ACID modulator and anti-anxiety agent.	3.23	1	0	benzodiazepine
temozolomide [no description available]	3.23	1	0	imidazotetrazine; monocarboxylic acid amide; triazene derivative	alkylating agent; antineoplastic agent; prodrug
terazosin Terazosin: induces decreased blood pressure; used in the treatment of benign prostatic hyperplasia	3.23	1	0	furans; piperazines; primary amino compound; quinazolines	alpha-adrenergic antagonist; antihypertensive agent; antineoplastic agent
terbutaline Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.. terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.	3.23	1	0	phenylethanolamines; resorcinols	anti-asthmatic drug; beta-adrenergic agonist; bronchodilator agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; hypoglycemic agent; sympathomimetic agent; tocolytic agent
terfenadine Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.	2.08	1	0	diarylmethane
tetraethylammonium Tetraethylammonium: A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)	2.05	1	0	quaternary ammonium ion
thalidomide Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.. thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.. 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.	4.4	3	0	phthalimides; piperidones
thiabendazole Tresaderm: dermatologic soln containing dexamethasone, thiabendazole & neomycin sulfate	3.23	1	0	1,3-thiazoles; benzimidazole fungicide; benzimidazoles	antifungal agrochemical; antinematodal drug
thioridazine Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.. thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.	4.45	3	0	phenothiazines; piperidines	alpha-adrenergic antagonist; dopaminergic antagonist; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; first generation antipsychotic; H1-receptor antagonist; serotonergic antagonist
thiotepa Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).	3.23	1	0	aziridines
ticlopidine Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.. ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.	3.23	1	0	monochlorobenzenes; thienopyridine	anticoagulant; fibrin modulating drug; hematologic agent; P2Y12 receptor antagonist; platelet aggregation inhibitor
tinidazole Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.. tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.	3.23	1	0	imidazoles	antiamoebic agent; antibacterial drug; antiparasitic agent; antiprotozoal drug
tiopronin Tiopronin: Sulfhydryl acylated derivative of GLYCINE.	3.23	1	0	N-acyl-amino acid
tizanidine tizanidine: RN given refers to parent cpd; structure. tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.	3.23	1	0	benzothiadiazole; imidazoles	alpha-adrenergic agonist; muscle relaxant
tolazamide Tolazamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.. tolazamide : An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus.	3.23	1	0	N-sulfonylurea	hypoglycemic agent; potassium channel blocker
tolbutamide Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290). tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.	3.23	1	0	N-sulfonylurea	human metabolite; hypoglycemic agent; insulin secretagogue; potassium channel blocker
tolmetin Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.. tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.	3.23	1	0	aromatic ketone; monocarboxylic acid; pyrroles	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-steroidal anti-inflammatory drug
2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine [no description available]	2.59	2	0	stilbenoid
ultram 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol : A tertiary alcohol that is cyclohexanol substituted at positions 1 and 2 by 3-methoxyphenyl and dimethylaminomethyl groups respectively.	3.23	1	0	aromatic ether; tertiary alcohol; tertiary amino compound
tranexamic acid Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.	3.23	1	0	amino acid
trazodone Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309). trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.	3.23	1	0	monochlorobenzenes; N-alkylpiperazine; N-arylpiperazine; triazolopyridine	adrenergic antagonist; antidepressant; anxiolytic drug; H1-receptor antagonist; sedative; serotonin uptake inhibitor
triamterene Triamterene: A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.. triamterene : Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.	3.23	1	0	pteridines	diuretic; sodium channel blocker
triazolam Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.	3.23	1	0	triazolobenzodiazepine	sedative
trifluoperazine [no description available]	3.23	1	0	N-alkylpiperazine; N-methylpiperazine; organofluorine compound; phenothiazines	antiemetic; calmodulin antagonist; dopaminergic antagonist; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor; phenothiazine antipsychotic drug
trifluperidol Trifluperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in the treatment of PSYCHOSES including MANIA and SCHIZOPHRENIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p621)	2.15	1	0	aromatic ketone
trihexyphenidyl Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.	3.23	1	0	amine
trimethadione Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378). trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.	3.23	1	0	oxazolidinone	anticonvulsant; geroprotector
trimethobenzamide trimethobenzamide: major descriptor (64-84); on-line search BENZAMIDES (64-84); Index Medicus search TRIMETHOBENZAMIDE (64-84); RN given refers to parent cpd. trimethobenzamide : The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.	3.23	1	0	benzamides; tertiary amino compound	antiemetic
trimethoprim Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.. trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.	3.23	1	0	aminopyrimidine; methoxybenzenes	antibacterial drug; diuretic; drug allergen; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; environmental contaminant; xenobiotic
trimetrexate Trimetrexate: A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.	3.23	1	0
trimipramine Trimipramine: Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.. trimipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.	3.23	1	0	dibenzoazepine; tertiary amino compound	antidepressant; environmental contaminant; xenobiotic
troglitazone Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.	3.61	2	0	chromanes; thiazolidinone	anticoagulant; anticonvulsant; antineoplastic agent; antioxidant; EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; hypoglycemic agent; platelet aggregation inhibitor; vasodilator agent
tyramine [no description available]	3.23	1	0	monoamine molecular messenger; primary amino compound; tyramines	EC 3.1.1.8 (cholinesterase) inhibitor; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter
tyrphostin a9 [no description available]	3.92	2	0	alkylbenzene	geroprotector
delavirdine Delavirdine: A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.. delavirdine : The amide resulting from the formal condensation of 5-[(methylsulfonyl)amino]-1H-indole-2-carboxylic acid and 4-amino group of 1-[3-(isopropylamino)pyridin-2-yl]piperazine, delavirdine is a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection.	4.22	2	0	aminopyridine; indolecarboxamide; N-acylpiperazine; sulfonamide	antiviral drug; HIV-1 reverse transcriptase inhibitor
venlafaxine venlafaxine : A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group.	3.23	1	0	cyclohexanols; monomethoxybenzene; tertiary alcohol; tertiary amino compound	adrenergic uptake inhibitor; analgesic; antidepressant; dopamine uptake inhibitor; environmental contaminant; serotonin uptake inhibitor; xenobiotic
vigabatrin [no description available]	3.23	1	0	gamma-amino acid	anticonvulsant; EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source. lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.	2.89	3	0	aromatic primary alcohol; furans; indazoles	antineoplastic agent; apoptosis inducer; platelet aggregation inhibitor; soluble guanylate cyclase activator; vasodilator agent
ici 204,219 zafirlukast: a leukotriene D4 receptor antagonist	3.59	2	0	carbamate ester; indoles; N-sulfonylcarboxamide	anti-asthmatic agent; leukotriene antagonist
zaleplon zaleplon: an azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; a hypnotic with less marked effect on psychomotor functions compared to lorazepam. zaleplon : A pyrazolo[1,5-a]pyrimidine having a nitrile group at position 3 and a 3-(N-ethylacetamido)phenyl substituent at the 7-position.	3.23	1	0	nitrile; pyrazolopyrimidine	anticonvulsant; anxiolytic drug; central nervous system depressant; sedative
zm 336372 N-(5-(3-dimethylaminobenzamido)-2-methylphenyl)-4-hydroxybenzamide: an inhibitor of c-Raf; activates Raf-1; structure in first source	2.04	1	0	benzamides
zolpidem Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.. zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.	3.23	1	0	imidazopyridine	central nervous system depressant; GABA agonist; sedative
zonisamide Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.. zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.	3.23	1	0	1,2-benzoxazoles; sulfonamide	anticonvulsant; antioxidant; central nervous system drug; protective agent; T-type calcium channel blocker
zotepine zotepine: structure	2.89	3	0	dibenzothiepine; tertiary amino compound	alpha-adrenergic drug; second generation antipsychotic; serotonergic drug
cortisone acetate Cortisone Acetate: The acetate ester of cortisone that is used mainly for replacement therapy in adrenocortical insufficiency and in the treatment of many allergic and inflammatory disorders.	3.23	1	0	corticosteroid hormone
mitomycin Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.. mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.	3.23	1	0	mitomycin	alkylating agent; antineoplastic agent
corticosterone [no description available]	2.41	1	0	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite
prednisolone Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.. prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.	9.67	9	3	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antineoplastic agent; drug metabolite; environmental contaminant; immunosuppressive agent; xenobiotic
reserpine Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.. reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.	4.22	2	0	alkaloid ester; methyl ester; yohimban alkaloid	adrenergic uptake inhibitor; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; first generation antipsychotic; plant metabolite; xenobiotic
phentolamine Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.. phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.	3.23	1	0	imidazoles; phenols; substituted aniline; tertiary amino compound	alpha-adrenergic antagonist; vasodilator agent
sorbitol D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).	3.23	1	0	glucitol	cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent
thymidine [no description available]	2.07	1	0	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite
hydroxyproline Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.. hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.	2.51	2	0	4-hydroxyproline; L-alpha-amino acid zwitterion	human metabolite; mouse metabolite; plant metabolite
thyroxine Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.. thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.	3.23	1	0	2-halophenol; iodophenol; L-phenylalanine derivative; non-proteinogenic L-alpha-amino acid; thyroxine zwitterion; thyroxine	antithyroid drug; human metabolite; mouse metabolite; thyroid hormone
dextroamphetamine Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.. (S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.	3.23	1	0	1-phenylpropan-2-amine	adrenergic agent; adrenergic uptake inhibitor; dopamine uptake inhibitor; dopaminergic agent; neurotoxin; sympathomimetic agent
spironolactone Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827). spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.	3.23	1	0	3-oxo-Delta(4) steroid; oxaspiro compound; steroid lactone; thioester	aldosterone antagonist; antihypertensive agent; diuretic; environmental contaminant; xenobiotic
penicillamine Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.. penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.	3.23	1	0	non-proteinogenic alpha-amino acid; penicillamine	antirheumatic drug; chelator; copper chelator; drug allergen
cysteine [no description available]	3.23	1	0	cysteine zwitterion; cysteine; L-alpha-amino acid; proteinogenic amino acid; serine family amino acid	EC 4.3.1.3 (histidine ammonia-lyase) inhibitor; flour treatment agent; human metabolite
prednisone Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.. prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.	4.29	5	0	11-oxo steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antineoplastic agent; immunosuppressive agent; prodrug
estrone Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.	3.23	1	0	17-oxo steroid; 3-hydroxy steroid; phenolic steroid; phenols	antineoplastic agent; bone density conservation agent; estrogen; human metabolite; mouse metabolite
oxandrolone Oxandrolone: A synthetic hormone with anabolic and androgenic properties.	3.23	1	0	17beta-hydroxy steroid; 3-oxo steroid; anabolic androgenic steroid; oxa-steroid	anabolic agent; androgen
penicillin g Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.. benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.	3.23	1	0	penicillin allergen; penicillin	antibacterial drug; drug allergen; epitope
pilocarpine Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.. (+)-pilocarpine : The (+)-enantiomer of pilocarpine.	3.23	1	0	pilocarpine	antiglaucoma drug
pentylenetetrazole Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.. pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.	2.21	1	0	organic heterobicyclic compound; organonitrogen heterocyclic compound
triiodothyronine Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.. 3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.	3.23	1	0	2-halophenol; amino acid zwitterion; iodophenol; iodothyronine	human metabolite; mouse metabolite; thyroid hormone
carbon tetrachloride Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed). tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.	2.83	3	0	chlorocarbon; chloromethanes	hepatotoxic agent; refrigerant
alanine Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.	2.11	1	0	alanine zwitterion; alanine; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor; fundamental metabolite
chloramphenicol Amphenicol: Chloramphenicol and its derivatives.	3.23	1	0	C-nitro compound; carboxamide; diol; organochlorine compound	antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor
glutamine Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.	3.23	1	0	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
lysine Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine.	2.07	1	0	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
vincristine [no description available]	3.23	1	0	acetate ester; formamides; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; tertiary alcohol; tertiary amino compound; vinca alkaloid	antineoplastic agent; drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
physostigmine Physostigmine: A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.	3.23	1	0	carbamate ester; indole alkaloid	antidote to curare poisoning; EC 3.1.1.8 (cholinesterase) inhibitor; miotic
tubocurarine Tubocurarine: A neuromuscular blocker and active ingredient in CURARE; plant based alkaloid of Menispermaceae.. tubocurarine : A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.. isoquinoline alkaloid : Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine.	2.21	1	0	bisbenzylisoquinoline alkaloid	drug allergen; muscle relaxant; nicotinic antagonist
apomorphine Apomorphine: A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.	3.23	1	0	aporphine alkaloid	alpha-adrenergic drug; antidyskinesia agent; antiparkinson drug; dopamine agonist; emetic; serotonergic drug
methyltestosterone Methyltestosterone: A synthetic hormone used for androgen replacement therapy and as an hormonal antineoplastic agent (ANTINEOPLASTIC AGENTS, HORMONAL).. methyltestosterone : A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position.	3.23	1	0	17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; enone	anabolic agent; androgen; antineoplastic agent
tetrabenazine 9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one : A benzoquinolizine that is 1,2,3,4,4a,9,10,10a-octahydrophenanthrene in which the carbon at position 10a is replaced by a nitrogen and which is substituted by an isobutyl group at position 2, an oxo group at position 3, and methoxy groups at positions 6 and 7.	3.23	1	0	benzoquinolizine; cyclic ketone; tertiary amino compound
kanamycin a Kanamycin: Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.. kanamycin : Kanamycin is a naturally occurring antibiotic complex from Streptomyces kanamyceticus that consists of several components: kanamycin A, the major component (also usually designated as kanamycin), and kanamycins B, C, D and X the minor components.	3.23	1	0	kanamycins	bacterial metabolite
carbostyril Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.	2.13	1	0	monohydroxyquinoline; quinolone	bacterial xenobiotic metabolite
levodopa Levodopa: The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.. L-dopa : An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease	3.7	1	1	amino acid zwitterion; dopa; L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	allelochemical; antidyskinesia agent; antiparkinson drug; dopaminergic agent; hapten; human metabolite; mouse metabolite; neurotoxin; plant growth retardant; plant metabolite; prodrug
edetic acid Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.	3.23	1	0	ethylenediamine derivative; polyamino carboxylic acid; tetracarboxylic acid	anticoagulant; antidote; chelator; copper chelator; geroprotector
tyrosine Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.	3	4	0	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
cysteamine Cysteamine: A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.. cysteamine : An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2.	3.23	1	0	amine; thiol	geroprotector; human metabolite; mouse metabolite; radiation protective agent
acetylcholine chloride acetylcholine chloride : The chloride salt of acetylcholine, and a parasympatomimetic drug.	3.23	1	0	quaternary ammonium salt
mepazine mepazine: major descriptor (66-85); on-line search PHENOTHIAZINES (66-85); Index Medicus search MEPAZINE (66-85); RN given refers to parent cpd. pacatal : A phenothiazine derivative in which 10H-phenothiazine has an N-methylpiperidin-4-ylmethyl substituent at the N-10 position.	3.23	1	0	phenothiazines
cloxacillin Cloxacillin: A semi-synthetic antibiotic that is a chlorinated derivative of OXACILLIN.. cloxacillin : A semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6.	3.23	1	0	penicillin allergen; penicillin; semisynthetic derivative	antibacterial agent; antibacterial drug
methylene blue Methylene Blue: A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.. methylene blue : An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.	2.15	1	0	organic chloride salt	acid-base indicator; antidepressant; antimalarial; antimicrobial agent; antioxidant; cardioprotective agent; EC 1.4.3.4 (monoamine oxidase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 4.6.1.2 (guanylate cyclase) inhibitor; fluorochrome; histological dye; neuroprotective agent; physical tracer
leucine Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.	2.07	1	0	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
calcium acetate calcium acetate: a principal compound used as phosphate binders in patients with chronic renal failure; used like sevelamer. calcium acetate : The calcium salt of acetic acid. It is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is excreted in the faeces.	3.23	1	0	calcium salt	chelator
methionine Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.	3.23	1	0	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical
phenylalanine Phenylalanine: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.. L-phenylalanine : The L-enantiomer of phenylalanine.. phenylalanine : An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.	2.07	1	0	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
colchicine (S)-colchicine : A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions.	4.38	5	0	alkaloid; colchicine	anti-inflammatory agent; gout suppressant; mutagen
mebanazine mebanazine: RN given refers to parent cpd without isomeric designation; structure	3.23	1	0	benzenes
oxacillin Oxacillin: An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.. oxacillin : A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta.	3.23	1	0	penicillin	antibacterial agent; antibacterial drug
cycloheximide Cycloheximide: Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.. cycloheximide : A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.	2.04	1	0	antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol	anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor
cycloserine Cycloserine: Antibiotic substance produced by Streptomyces garyphalus.. D-cycloserine : A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanine--D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis).	3.23	1	0	4-amino-1,2-oxazolidin-3-one; organonitrogen heterocyclic antibiotic; organooxygen heterocyclic antibiotic; zwitterion	antiinfective agent; antimetabolite; antitubercular agent; metabolite; NMDA receptor agonist
benziodarone benziodarone: minor descriptor (75-89); on-line & INDEX MEDICUS search BENZOFURANS (68-89) & IODOBENZOATES (74)	4.19	4	0	aromatic ketone
ampicillin Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.. ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.	3.23	1	0	beta-lactam antibiotic; penicillin allergen; penicillin	antibacterial drug
mannitol [no description available]	3.23	1	0	mannitol	allergen; antiglaucoma drug; compatible osmolytes; Escherichia coli metabolite; food anticaking agent; food bulking agent; food humectant; food stabiliser; food thickening agent; hapten; metabolite; osmotic diuretic; sweetening agent
cytarabine [no description available]	5.1	7	0	beta-D-arabinoside; monosaccharide derivative; pyrimidine nucleoside	antimetabolite; antineoplastic agent; antiviral agent; immunosuppressive agent
trifluridine Trifluridine: An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557). trifluridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-trifluoromethyluracil as the nucleobase. An antiviral drug used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis.	2.03	1	0	nucleoside analogue; organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; EC 2.1.1.45 (thymidylate synthase) inhibitor
isoleucine Isoleucine: An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.. isoleucine : A 2-amino-3-methylpentanoic acid having either (2R,3R)- or (2S,3S)-configuration.. L-isoleucine : The L-enantiomer of isoleucine.	2.07	1	0	aspartate family amino acid; isoleucine; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
arginine Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group.	3.64	2	0	arginine; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	biomarker; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical
perflutren Definity: a fluorocarbon-filled ultrasonic contrast agent; Definity is tradename. octafluoropropane : A fluorocarbon that is propane in which all of the hydrogens have been replaced by fluorines.	3.23	1	0	fluoroalkane; fluorocarbon
fluoxymesterone Fluoxymesterone: An anabolic steroid that has been used in the treatment of male HYPOGONADISM, delayed puberty in males, and in the treatment of breast neoplasms in women.	3.23	1	0	11beta-hydroxy steroid; 17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; anabolic androgenic steroid; fluorinated steroid	anabolic agent; antineoplastic agent
methsuximide methsuximide: anticonvulsant effective in petit mal & psychomotor epilepsy; has a number of unpleasant & toxic side effects; minor descriptor (75-86); on-line & INDEX MEDICUS search SUCCINIMIDES (75-86); RN given refers to parent cpd without isomeric designation	3.23	1	0	organic molecular entity
tromethamine Tromethamine: An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)	3.23	1	0	primary amino compound; triol	buffer
cyclizine Cyclizine: A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935). cyclizine : An N-alkylpiperazine in which one nitrogen of the piperazine ring is substituted by a methyl group, while the other is substituted by a diphenylmethyl group.	2.21	1	0	N-alkylpiperazine	antiemetic; central nervous system depressant; cholinergic antagonist; H1-receptor antagonist; local anaesthetic
methylprednisolone Methylprednisolone: A PREDNISOLONE derivative with similar anti-inflammatory action.. 6alpha-methylprednisolone : The 6alpha-stereoisomer of 6-methylprednisolone.	3.23	1	0	6-methylprednisolone; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antiemetic; environmental contaminant; neuroprotective agent; xenobiotic
brompheniramine Brompheniramine: Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.. brompheniramine : Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.	3.23	1	0	organobromine compound; pyridines	anti-allergic agent; H1-receptor antagonist
penicillin v Penicillin V: A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.. phenoxymethylpenicillin : A penicillin compound having a 6beta-(phenoxyacetyl)amino side-chain.	3.23	1	0	penicillin allergen; penicillin
isosorbide dinitrate Isosorbide Dinitrate: A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.	3.23	1	0	glucitol derivative; nitrate ester	nitric oxide donor; vasodilator agent
pseudoephedrine Pseudoephedrine: A phenethylamine that is an isomer of EPHEDRINE which has less central nervous system effects and usage is mainly for respiratory tract decongestion.. pseudoephedrine : A member of the class of the class of phenylethanolamines that is (1S)-2-(methylamino)-1-phenylethan-1-ol in which the pro-S hydrogen at position 2 is replaced by a methyl group.	3.23	1	0	phenylethanolamines; secondary alcohol; secondary amino compound	anti-asthmatic drug; bronchodilator agent; central nervous system drug; nasal decongestant; plant metabolite; sympathomimetic agent; vasoconstrictor agent; xenobiotic
diethylpropion Diethylpropion: A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290). diethylpropion : An aromatic ketone that is propiophenone in which one of the hydrogens alpha- to the carbonyl is substituted by a diethylamino group. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as the hydrochloride as an anoretic in the short term management of obesity.	3.23	1	0	aromatic ketone; tertiary amine	appetite depressant
quinoxalines quinoxaline : A naphthyridine in which the nitrogens are at positions 1 and 4.	2.1	1	0	mancude organic heterobicyclic parent; naphthyridine; ortho-fused heteroarene
trehalose alpha,alpha-trehalose : A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon.	2.89	3	0	trehalose	Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
triclocarban triclocarban: bacteriostat; antiseptic in soaps & other cleansing solns; germicide; structure. triclocarban : A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.	2.89	3	0	dichlorobenzene; monochlorobenzenes; phenylureas	antimicrobial agent; antiseptic drug; disinfectant; environmental contaminant; xenobiotic
benzonatate benzonatate: structure in Merck Index, 9th ed, #1107. benzonatate : The ester obtained by formal condensation of 4-butylaminobenzoic acid with nonaethylene glycol monomethyl ether. Structurally related to procaine and benzocaine, it has an anaesthetic effect on the stretch sensors in the lungs, and is used as a non-narcotic cough suppressant.	3.23	1	0	benzoate ester; secondary amino compound; substituted aniline	anaesthetic; antitussive
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	12.78	38	3	pyrrole; secondary amine
methylergonovine Methylergonovine: A homolog of ERGONOVINE containing one more CH2 group. (Merck Index, 11th ed)	3.23	1	0	ergoline alkaloid
pyrazolanthrone pyrazolanthrone: JNK (c-Jun N-terminal kinase) inhibitor; structure in first source. anthra[1,9-cd]pyrazol-6(2H)-one : A member of the class of anthrapyrazoles that is anthra[1,9-cd]pyrazole substituted at position 6 by an oxo group. An inhibitor of c-Jun N-terminal kinase.	4.03	3	0	anthrapyrazole; aromatic ketone; cyclic ketone	antineoplastic agent; c-Jun N-terminal kinase inhibitor; geroprotector
cinchophen cinchophen: was heading 1963-94; ACIPHENOCHINOLIUM was see CHINOPHEN 1978-94; use QUINOLINES to search CINCHOPHEN 1966-94	3.23	1	0	quinolines
4-tert-octylphenol 4-tert-octylphenol: structure given in first source	2.89	3	0	alkylbenzene
nafcillin Nafcillin: A semi-synthetic antibiotic related to penicillin.. nafcillin : A penicillin in which the substituent at position 6 of the penam ring is a (2-ethoxy-1-naphthoyl)amino group.	3.23	1	0	penicillin allergen; penicillin	antibacterial drug
methohexital Methohexital: An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.. methohexital : A barbiturate, the structure of which is that of barbituric acid substituted at N-1 by a methyl group and at C-5 by allyl and 1-methylpent-2-ynyl groups.	3.23	1	0	acetylenic compound; barbiturates	drug allergen; intravenous anaesthetic
quinazolines Quinazolines: A group of aromatic heterocyclic compounds that contain a bicyclic structure with two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring.. quinazoline : A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.. quinazolines : Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives.	7.89	19	0	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinazolines
indazoles Indazoles: A group of heterocyclic aromatic organic compounds consisting of the fusion of BENZENE and PYRAZOLES.	4.17	4	0	indazole
1,3-benzodioxole 1,3-benzodioxole : A benzodioxole consisting of a benzene ring substituted by a the methylenedioxy group.	3.51	1	0	benzodioxole
adamantane Adamantane: A tricyclo bridged hydrocarbon.	2.17	1	0	adamantanes; polycyclic alkane
isoxazoles Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.	2.06	1	0	isoxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
thiazoles [no description available]	20.64	327	23	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
pyrazines Pyrazines: A heterocyclic aromatic organic compound with the chemical formula C4H4N2.. pyrazine : A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms.	4.7	8	0	diazine; pyrazines	Daphnia magna metabolite
ephedrine Ephedrine: A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.. (-)-ephedrine : A phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively.	3.23	1	0	phenethylamine alkaloid; phenylethanolamines	bacterial metabolite; environmental contaminant; nasal decongestant; plant metabolite; sympathomimetic agent; vasoconstrictor agent; xenobiotic
hydrazine diamine : Any polyamine that contains two amino groups.	3.14	1	0	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
ethamivan ethamivan: minor descriptor (65-72); major descriptor (73-86); on-line search BENZAMIDES (66-86); INDEX MEDICUS search BENZAMIDES (65-72); ETHAMIVAN (73-86). etamivan : Phenol substituted at C-2 and C-4 by a methoxy group and an N,N-diethylaminocarbonyl group respectively. A respiratory stimulant drug related to nikethamide, it has now fallen largely into disuse.	2.89	3	0	methoxybenzenes; phenols
monocrotaline Monocrotaline: A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.	2.07	1	0	pyrrolizidine alkaloid
aminophylline Aminophylline: A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.. aminophylline : A mixture comprising of theophylline and ethylenediamine in a 2:1 ratio.	3.23	1	0	mixture	bronchodilator agent; cardiotonic drug
azacitidine Azacitidine: A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.. 5-azacytidine : An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.	4.31	5	0	N-glycosyl-1,3,5-triazine; nucleoside analogue	antineoplastic agent
galantamine Galantamine: A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.. galanthamine : A benzazepine alkaloid isolated from certain species of daffodils.	3.23	1	0	benzazepine alkaloid fundamental parent; benzazepine alkaloid; organic heterotetracyclic compound; tertiary amino compound	antidote to curare poisoning; cholinergic drug; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant metabolite
nandrolone decanoate Nandrolone Decanoate: Decanoic acid ester of nandrolone that is used as an anabolic agent to prevent or treat WASTING SYNDROME associated with severe chronic illness or HIV infection (HIV WASTING SYNDROME). It may also be used in the treatment of POSTMENOPAUSAL OSTEOPOROSIS.	3.23	1	0	steroid ester
methysergide Methysergide: An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.. methysergide : A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.	2.89	3	0	ergoline alkaloid
dextropropoxyphene Dextropropoxyphene: A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.. propoxyphene : A racemate of the (1R,2R)- and (1S,2R)- diastereoisomers.. dextropropoxyphene : The (1S,2R)-(+)-diastereoisomer of propoxyphene.	3.23	1	0	1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate	mu-opioid receptor agonist; opioid analgesic
limestone Calcium Carbonate: Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.. calcium carbonate : A calcium salt with formula CCaO3.	3.47	1	1	calcium salt; carbonate salt; inorganic calcium salt; one-carbon compound	antacid; fertilizer; food colouring; food firming agent
chenodeoxycholic acid Chenodeoxycholic Acid: A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.. chenodeoxycholic acid : A dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively.. chenodeoxycholate : Conjugate base of chenodeoxycholic acid; major species at pH 7.3.	3.23	1	0	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite
cepharanthine cepharanthine: isoquinoline alkaloid from tubers of STEPHANIA; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation. cepharanthine : A bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation.	3.19	1	0	bisbenzylisoquinoline alkaloid; isoquinolines
emetine Emetine: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.. emetine : A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.	2.89	3	0	isoquinoline alkaloid; pyridoisoquinoline	antiamoebic agent; anticoronaviral agent; antiinfective agent; antimalarial; antineoplastic agent; antiprotozoal drug; antiviral agent; autophagy inhibitor; emetic; expectorant; plant metabolite; protein synthesis inhibitor
4-hydroxybutyric acid 4-hydroxybutyric acid: was an entry term to Sodium Oxybate (74-98). 4-hydroxybutyric acid : A 4-hydroxy monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a hydroxy group.	3.23	1	0	4-hydroxy monocarboxylic acid; hydroxybutyric acid	general anaesthetic; GHB receptor agonist; neurotoxin; sedative
dihydroergotamine Dihydroergotamine: A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the therapy of MIGRAINE DISORDERS.. dihydroergotamine : Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension.	3.23	1	0	ergot alkaloid; semisynthetic derivative	dopamine agonist; non-narcotic analgesic; serotonergic agonist; sympatholytic agent; vasoconstrictor agent
podophyllotoxin Podophyllum: A genus of poisonous American herbs, family BERBERIDACEAE. The roots yield PODOPHYLLOTOXIN and other pharmacologically important agents. The plant was formerly used as a cholagogue and cathartic. It is different from the European mandrake, MANDRAGORA.	3.07	4	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antimitotic; antineoplastic agent; keratolytic drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
medroxyprogesterone [no description available]	3.23	1	0	17alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(4) steroid; tertiary alpha-hydroxy ketone	contraceptive drug; progestin; synthetic oral contraceptive
dimenhydrinate gravinol: has antioxidant and ant-inflammatory activities; structure in first source	3.23	1	0	diarylmethane
gluconic acid gluconic acid: zinc gluconate has anti-inflammatory activity; RN given refers to (D)-isomer; all RRs refers to (D)-isomer unless otherwise noted. ketogluconic acid : A gluconic acid that contains a ketonic carbonyl group.. D-gluconic acid : A gluconic acid having D-configuration.	2.1	1	0	gluconic acid	chelator; Penicillium metabolite
copper gluconate Gluconates: Derivatives of gluconic acid (the structural formula HOCH2(CHOH)4COOH), including its salts and esters.	2.1	1	0	organic molecular entity
methamphetamine Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.. methamphetamine : A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.	3.23	1	0	amphetamines; secondary amine	central nervous system stimulant; environmental contaminant; neurotoxin; psychotropic drug; xenobiotic
levocarnitine (R)-carnitine : The (R)-enantiomer of carnitine.	3.23	1	0	carnitine	antilipemic drug; nootropic agent; nutraceutical; Saccharomyces cerevisiae metabolite; water-soluble vitamin (role)
malondialdehyde Malondialdehyde: The dialdehyde of malonic acid.. malonaldehyde : A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.	2.84	3	0	dialdehyde	biomarker
myristic acid Myristic Acid: A saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. It is used to synthesize flavor and as an ingredient in soaps and cosmetics. (From Dorland, 28th ed). tetradecanoic acid : A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.. tetradecanoate : A long-chain fatty acid anion that is the conjugate base of myristic acid; major species at pH 7.3.	2.06	1	0	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite
sulfanilylurea sulfanilylurea: antimicrobial agent; structure	3.23	1	0	benzenes; sulfonamide
trinitrobenzenesulfonic acid Trinitrobenzenesulfonic Acid: A reagent that is used to neutralize peptide terminal amino groups.. 2,4,6-trinitrobenzenesulfonic acid : The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.	2.08	1	0	arenesulfonic acid; C-nitro compound	epitope; explosive; reagent
formestane [no description available]	2.08	1	0	17-oxo steroid; 3-oxo-Delta(4) steroid; enol; hydroxy steroid	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
lactulose [no description available]	3.23	1	0	glycosylfructose	gastrointestinal drug; laxative
diphenylamine Diphenylamine: In humans it may be irritating to mucous membranes. Methemoglobinemia has been produced experimentally. In veterinary use, it is one of active ingredients in topical agents for prevention and treatment of screwworm infestation. An indicator in tests for nitrate poisoning.. diphenylamine : An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union.	2.05	1	0	aromatic amine; bridged diphenyl fungicide; secondary amino compound	antifungal agrochemical; antioxidant; carotogenesis inhibitor; EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor; ferroptosis inhibitor; radical scavenger
pamabrom [no description available]	3.23	1	0
acetylcysteine N-acetyl-L-cysteine : An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.	3.23	1	0	acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid	antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary
erythromycin Erythromycin: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.. erythromycin : Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus).. erythromycin A : An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively.	3.23	1	0	cyclic ketone; erythromycin
hydroxychloroquine sulfate [no description available]	2.08	1	0
ethylnitrosourea Ethylnitrosourea: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.. N-ethyl-N-nitrosourea : A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.	2.03	1	0	N-nitrosoureas	alkylating agent; carcinogenic agent; genotoxin; mutagen
levonorgestrel Levonorgestrel: A synthetic progestational hormone with actions similar to those of PROGESTERONE and about twice as potent as its racemic or (+-)-isomer (NORGESTREL). It is used for contraception, control of menstrual disorders, and treatment of endometriosis.	3.23	1	0	17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; terminal acetylenic compound	contraceptive drug; female contraceptive drug; progestin; synthetic oral contraceptive
4-methylimidazole 4-methylimidazole: RN given refers to parent cpd. 4-methylimidazole : Imidazole substituted at position 4 by a methyl group.	2.07	1	0	imidazoles	carcinogenic agent; reaction intermediate
etonitazene etonitazene: was heading 1979-94 (see under BENZIMIDAZOLES 1979-90); ETONITAZIN was see ETONITAZENE 1979-94; use BENZIMIDAZOLES to search ETONITAZENE 1979-94; narcotic analgesic similar to morphine in action; used mainly to study narcotic habituation, tolerance, and withdrawal in laboratory animals	2.89	3	0
diphenoxylate Diphenoxylate: A MEPERIDINE congener used as an antidiarrheal, usually in combination with ATROPINE. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity.. diphenoxylate : A piperidinecarboxylate ester that is the ethyl ester of difenoxin.	3.23	1	0	ethyl ester; nitrile; piperidinecarboxylate ester; tertiary amine	antidiarrhoeal drug
ethambutol Ethambutol: An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863). ethambutol : An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.	3.23	1	0	ethanolamines; ethylenediamine derivative	antitubercular agent; environmental contaminant; xenobiotic
arsenic trioxide Arsenic Trioxide: An inorganic compound with the chemical formula As2O3 that is used for the treatment of ACUTE PROMYELOCYTIC LEUKEMIA in patients who have relapsed from, or are resistant to, conventional drug therapy.	2.08	1	0
vancomycin Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.	3.23	1	0	glycopeptide	antibacterial drug; antimicrobial agent; bacterial metabolite
d-alpha tocopherol Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.. tocopherol : A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.. vitamin E : Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.. (R,R,R)-alpha-tocopherol : An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.	3.23	1	0	alpha-tocopherol	algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite
ibufenac ibufenac: used in the treatment of rheumatism; also possesses antipyretic properties; minor descriptor (75-84); on-line & Index Medicus search PHENYLACETATES (75-84); RN given refers to parent cpd. ibufenac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 4-isobutylphenyl group. Although it was shown to be effective in treatment of rheumatoid arthritis, the clinical use of ibufenac was discontinued due to hepatotoxic side-effects.	3.23	1	0	monocarboxylic acid	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; hepatotoxic agent; non-narcotic analgesic; non-steroidal anti-inflammatory drug
metaxalone [no description available]	3.23	1	0	aromatic ether
spectinomycin Spectinomycin: An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of GONORRHEA.. spectinomycin dihydrochloride : A hydrochloride obtained by combining spectinomycin with two molar equivalents of hydrochloric acid. An antibiotic that is active against gram-negative bacteria and used (as its pentahydrate) to treat gonorrhea.. spectinomycin : A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis.	3.23	1	0	cyclic acetal; cyclic hemiketal; cyclic ketone; pyranobenzodioxin; secondary alcohol; secondary amino compound	antibacterial drug; antimicrobial agent; bacterial metabolite
dronabinol Dronabinol: A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.. Delta(9)-tetrahydrocannabinol : A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. The principal psychoactive constituent of the cannabis plant, it is used for treatment of anorexia associated with AIDS as well as nausea and vomiting associated with cancer chemotherapy.	3.23	1	0	benzochromene; diterpenoid; phytocannabinoid; polyketide	cannabinoid receptor agonist; epitope; hallucinogen; metabolite; non-narcotic analgesic
amiloride hydrochloride, anhydrous amiloride hydrochloride : A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.	2.08	1	0	hydrochloride	diuretic; sodium channel blocker
amiloride Amiloride: A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705). amiloride : A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.	3.66	2	0	aromatic amine; guanidines; organochlorine compound; pyrazines	diuretic; sodium channel blocker
clothiapine clothiapine: was heading 1975-94 (was see under DIBENZOTHIAZEPINES 1975-90); CLOTIAPINE was see CLOTHIAPINE 1978-94; use DIBENZOTHIAZEPINES to search CLOTHIAPINE 1975-94; antipsychotic similar to clozapine	2.89	3	0	dibenzothiazepine
pimozide Pimozide: A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403). pimozide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluorophenyl)butyl group.	3.61	2	0	benzimidazoles; heteroarylpiperidine; organofluorine compound	antidyskinesia agent; dopaminergic antagonist; first generation antipsychotic; H1-receptor antagonist; serotonergic antagonist
benperidol Benperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It has been used in the treatment of aberrant sexual behavior. (From Martindale, The Extra Pharmacopoeia, 30th ed, p567)	2.89	3	0	aromatic ketone
7-hydroxychlorpromazine 7-hydroxychlorpromazine: RN given refers to parent cpd	2.89	3	0	phenothiazines
dexbrompheniramine dexbrompheniramine : The (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.	3.23	1	0	brompheniramine	anti-allergic agent; H1-receptor antagonist
acadesine [no description available]	2.08	1	0	1-ribosylimidazolecarboxamide; aminoimidazole; nucleoside analogue	antineoplastic agent; platelet aggregation inhibitor
stavudine Stavudine: A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.. stavudine : A nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase	3.23	1	0	dihydrofuran; nucleoside analogue; organic molecular entity	antimetabolite; antiviral agent; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
dicloxacillin Dicloxacillin: One of the PENICILLINS which is resistant to PENICILLINASE.. dicloxacillin : A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group.	3.23	1	0	dichlorobenzene; penicillin	antibacterial drug
megestrol Megestrol: A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.. megestrol : A 3-oxo Delta(4)-steroid that is pregna-4,6-diene-3,20-dione substituted by a methyl group at position 6 and a hydroxy group at position 17.	3.23	1	0	17alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(4) steroid; tertiary alpha-hydroxy ketone	antineoplastic agent; appetite enhancer; contraceptive drug; progestin; synthetic oral contraceptive
streptomycin [no description available]	3.23	1	0	antibiotic antifungal drug; antibiotic fungicide; streptomycins	antibacterial drug; antifungal agrochemical; antimicrobial agent; antimicrobial drug; bacterial metabolite; protein synthesis inhibitor
cladribine [no description available]	4.26	5	0	organochlorine compound; purine 2'-deoxyribonucleoside	antineoplastic agent; immunosuppressive agent
carbenicillin Carbenicillin: Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.. carbenicillin : A penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain.	3.23	1	0	penicillin allergen; penicillin	antibacterial drug
clomacran clomacran: RN given refers to parent cpd; structure	3.23	1	0	acridines
vidarabine adenine arabinoside : A purine nucleoside in which adenine is attached to arabinofuranose via a beta-N(9)-glycosidic bond.	4.76	5	0	beta-D-arabinoside; purine nucleoside	antineoplastic agent; bacterial metabolite; nucleoside antibiotic
methenamine hippurate methenamine hippurate: both parts of molecule contribute to its antibacterial action	3.23	1	0	N-acylglycine
olsalazine olsalazine: cpd with 2 salicylate molecules linked together by an azo bond. olsalazine : An azobenzene that consists of two molecules of 4-aminosalicylic acid joined by an azo linkage. A prodrug for mesalazine, an anti-inflammatory drug, it is used (as the disodium salt) in the treatment of inflammatory bowel disease.	3.23	1	0	azobenzenes; dicarboxylic acid	non-steroidal anti-inflammatory drug; prodrug
terodiline [no description available]	2.08	1	0	diarylmethane
palladium Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.	2.07	1	0	metal allergen; nickel group element atom; platinum group metal atom
gold Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.	2.15	1	0	copper group element atom; elemental gold
galactosamine 2-amino-2-deoxy-D-galactopyranose : The pyranose form of D-galactosamine.. D-galactosamine : The D-stereoisomer of galactosamine.	2.17	1	0	D-galactosamine; primary amino compound	toxin
camptothecin NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source	3.06	4	0	delta-lactone; pyranoindolizinoquinoline; quinoline alkaloid; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; genotoxin; plant metabolite
sodium thiosulfate sodium thiosulfate: do not confuse synonym sodium hyposulfite with sodium hyposulfite, synonym for di-Na salt of dithionous acid. sodium thiosulfate : An inorganic sodium salt composed of sodium and thiosulfate ions in a 2:1 ratio.	3.23	1	0	inorganic sodium salt	antidote to cyanide poisoning; antifungal drug; nephroprotective agent
fluorine Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	2.08	1	0	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
selegiline Selegiline: A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.	3.23	1	0	selegiline; terminal acetylenic compound	geroprotector
clemastine Clemastine: A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.. clemastine : 2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions.	3.23	1	0	monochlorobenzenes; N-alkylpyrrolidine	anti-allergic agent; antipruritic drug; H1-receptor antagonist; muscarinic antagonist
cephalexin Cephalexin: A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.. cephalexin : A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract.	3.23	1	0	beta-lactam antibiotic allergen; cephalosporin; semisynthetic derivative	antibacterial drug
thenalidine thenalidine: antihistaminic, antipruritic; RN in Chemline for thenalidine calcium: 67250-62-8; structure	2.89	3	0	dialkylarylamine; tertiary amino compound
danazol Danazol: A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.	3.23	1	0	17beta-hydroxy steroid; terminal acetylenic compound	anti-estrogen; estrogen antagonist; geroprotector
fenclozic acid fenclozic acid: an analgesic & antipyretic with anti-inflammatory properties; minor descriptor (75-86); on-line & INDEX MEDICUS search THIAZOLES (75-86); RN given refers to parent cpd	3.23	1	0
laxagetten 4,4'-diacetoxydiphenylpyridylemethane [no description available]	3.23	1	0
daunorubicin Daunorubicin: A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.. anthracycline : Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.. daunorubicin : A natural product found in Actinomadura roseola.	8.58	7	3	aminoglycoside antibiotic; anthracycline; p-quinones; tetracenequinones	antineoplastic agent; bacterial metabolite
fludarabine phosphate fludarabine phosphate: structure given in first source. fludarabine phosphate : A purine arabinonucleoside monophosphate having 2-fluoroadenine as the nucleobase. A prodrug, it is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. Once incorporated into DNA, 2-fluoro-ara-ATP functions as a DNA chain terminator. It is used for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to, or whose disease has progressed during, treatment with at least one standard alkylating-agent containing regimenas.	3.23	1	0	nucleoside analogue; organofluorine compound; purine arabinonucleoside monophosphate	antimetabolite; antineoplastic agent; antiviral agent; DNA synthesis inhibitor; immunosuppressive agent; prodrug
phosphotyrosine Phosphotyrosine: An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.. O(4)-phospho-L-tyrosine : A non-proteinogenic L-alpha-amino acid that is L-tyrosine phosphorylated at the phenolic hydroxy group.	2.96	4	0	L-tyrosine derivative; non-proteinogenic L-alpha-amino acid; O(4)-phosphotyrosine	Escherichia coli metabolite; immunogen
alclofenac alclofenac: was heading 1975-94 (was see under PHENYLACETATES 1975-90); use PHENYLACETATES to search ALCLOFENAC 1975-94; an anti-inflammatory agent used in the treatment of rheumatoid arthritis; acts also as an analgesic and an antipyretic. alclofenac : An aromatic ether in which the ether oxygen links an allyl group to the 4-position of (3-chlorophenyl)acetic acid.A non-steroidal anti-inflammatory drug, it was withdrawn from the UK market in 1979 due to concerns with its association with vasculitis and rash.	3.23	1	0	aromatic ether; monocarboxylic acid; monochlorobenzenes	drug allergen; non-narcotic analgesic; non-steroidal anti-inflammatory drug
bromocriptine Bromocriptine: A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.	4.19	4	0	indole alkaloid	antidyskinesia agent; antiparkinson drug; dopamine agonist; hormone antagonist
oxyphenisatin [no description available]	3.23	1	0	indoles
fludrocortisone Fludrocortisone: A synthetic mineralocorticoid with anti-inflammatory activity.	3.23	1	0	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; fluorinated steroid; mineralocorticoid	adrenergic agent; anti-inflammatory drug
ursodeoxycholic acid Ursodeoxycholic Acid: An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.. ursodeoxycholic acid : A bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones.. ursodeoxycholate : A bile acid anion that is the conjugate base of ursodeoxycholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.	3.23	1	0	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite
glutamic acid Glutamic Acid: A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.. glutamic acid : An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.	2.07	1	0	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical
dexchlorpheniramine dexchlorpheniramine: RN given refers to parent cpd(S)-isomer	4.19	4	0	chlorphenamine
clometacin clometacin: structure	3.23	1	0	N-acylindole
cefazolin Cefazolin: A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.. cefazolin : A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively.	3.23	1	0	beta-lactam antibiotic allergen; cephalosporin; tetrazoles; thiadiazoles	antibacterial drug
amoxicillin Amoxicillin: A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.. amoxicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group.	3.23	1	0	penicillin allergen; penicillin	antibacterial drug
timolol (S)-timolol (anhydrous) : The (S)-(-) (more active) enantiomer of timolol. A beta-adrenergic antagonist, both the hemihydrate and the maleate salt are used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.	3.23	1	0	timolol	anti-arrhythmia drug; antiglaucoma drug; antihypertensive agent; beta-adrenergic antagonist
dv 1006 [no description available]	2.89	3	0
nicergoline Nicergoline: An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It may ameliorate cognitive deficits in CEREBROVASCULAR DISORDERS.	2.15	1	0	organic heterotetracyclic compound; organonitrogen heterocyclic compound
oxcarbazepine Oxcarbazepine: A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.. oxcarbazepine : A dibenzoazepine derivative, having a carbamoyl group at the ring nitrogen, substituted with an oxo group at C-4 of the azepeine ring which is also hydrogenated at C-4 and C-5. It is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy.	3.23	1	0	cyclic ketone; dibenzoazepine	anticonvulsant; drug allergen
carbidopa carbidopa (anhydrous) : 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.	3.23	1	0	catechols; hydrazines; monocarboxylic acid	antiparkinson drug; dopaminergic agent; EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
moricizine Moricizine: An antiarrhythmia agent used primarily for ventricular rhythm disturbances.. moricizine : A phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group.	3.23	1	0	carbamate ester; morpholines; phenothiazines	anti-arrhythmia drug
amineptin amineptin: used in treatment of neuroses with psychoasthenic, anxio-phobic & depressive manifestations; synonym S 1694 refers to HCl; structure. amineptine : A carbocyclic fatty acid that is 5-aminoheptanoic acid in which one of the hydrogens attached to the nitrogen is replaced by a 10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl group. A tricyclic antidepressant, it was never approved in the US and was withdrawn from the French market in 1999 due to concerns over abuse, dependence and severe acne.	3.23	1	0	amino acid; carbocyclic fatty acid; carbotricyclic compound; secondary amino compound	antidepressant; dopamine uptake inhibitor
zidovudine Zidovudine: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.. zidovudine : A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.	3.61	2	0	azide; pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor
pirprofen pirprofen: anti-inflammatory agent used in therapy of rheumatoid arthritis; prostaglandin synthetase inhibitor; more potent than indomethacin; structure	3.23	1	0	pyrroline
paclitaxel Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).	5.64	8	0	taxane diterpenoid; tetracyclic diterpenoid	antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent
etoposide [no description available]	3.91	3	0	beta-D-glucoside; furonaphthodioxole; organic heterotetracyclic compound	antineoplastic agent; DNA synthesis inhibitor
dobutamine Dobutamine: A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.. dobutamine : A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.	3.23	1	0	catecholamine; secondary amine	beta-adrenergic agonist; cardiotonic drug; sympathomimetic agent
halofantrine halofantrine: used in treatment of mild to moderate acute malaria	2.08	1	0	phenanthrenes
penbutolol Penbutolol: A nonselective beta-blocker used as an antihypertensive and an antianginal agent.	3.23	1	0	ethanolamines
ribavirin Rebetron: Rebetron is tradename	3.61	2	0	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide	anticoronaviral agent; antiinfective agent; antimetabolite; antiviral agent; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
amikacin Amikacin: A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.. amikacin : An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.	3.23	1	0	alpha-D-glucoside; amino cyclitol glycoside; aminoglycoside; carboxamide	antibacterial drug; antimicrobial agent; nephrotoxin
climbazole 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one : A ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3.	2.89	3	0	aromatic ether; hemiaminal ether; imidazoles; ketone; monochlorobenzenes
cephradine Cephradine: A semi-synthetic cephalosporin antibiotic.. cephradine : A first-generation cephalosporin antibiotic with a methyl substituent at position 3, and a (2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetamido substituent at position 7, of the cephem skeleton.	3.23	1	0	beta-lactam antibiotic allergen; cephalosporin	antibacterial drug
ticrynafen Ticrynafen: A novel diuretic with uricosuric action. It has been proposed as an antihypertensive agent.. tienilic acid : An aromatic ketone that is 2,3-dichlorophenoxyacetic acid in which the hydrogen at position 4 on the benzene ring is replaced by a thiophenecarbonyl group. A loop diuretic used to treat hypertension, it was withdrawn from the market in 1982 due to links with hepatitis.	3.23	1	0	aromatic ether; aromatic ketone; dichlorobenzene; monocarboxylic acid; thiophenes	antihypertensive agent; hepatotoxic agent; loop diuretic
methyldopa Methyldopa: An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.. alpha-methyl-L-dopa : A derivative of L-tyrosine having a methyl group at the alpha-position and an additional hydroxy group at the 3-position on the phenyl ring.	3.23	1	0	L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	alpha-adrenergic agonist; antihypertensive agent; hapten; peripheral nervous system drug; sympatholytic agent
diltiazem Diltiazem: A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.. diltiazem : A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have S configuration. A calcium-channel blocker and vasodilator, it is used as the hydrochloride in the management of angina pectoris and hypertension.	3.61	2	0	5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate	antihypertensive agent; calcium channel blocker; vasodilator agent
lonidamine lonidamine: structure. lonidamine : A member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively.	2.08	1	0	dichlorobenzene; indazoles; monocarboxylic acid	antineoplastic agent; antispermatogenic agent; EC 2.7.1.1 (hexokinase) inhibitor; geroprotector
vecuronium vecuronium : A 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidino- and 16beta-N-methylpiperidinium substituents.	3.23	1	0	acetate ester; androstane; quaternary ammonium ion	drug allergen; muscle relaxant; neuromuscular agent; nicotinic antagonist
ng-nitroarginine methyl ester NG-Nitroarginine Methyl Ester: A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.	2.25	1	0	alpha-amino acid ester; L-arginine derivative; methyl ester; N-nitro compound	EC 1.14.13.39 (nitric oxide synthase) inhibitor
benoxaprofen benoxaprofen: RN given refers to parent cpd; structure. benoxaprofen : A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group. It was used as a non-steroidal anti-inflammatory drug until 1982 when it was withdrawn from the market due to adverse side-effects including liver necrosis, photosensitivity, and carcinogenicity in animals.	3.23	1	0	1,3-benzoxazoles; monocarboxylic acid; monochlorobenzenes	antipsoriatic; antipyretic; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; hepatotoxic agent; nephrotoxin; non-narcotic analgesic; non-steroidal anti-inflammatory drug; protein kinase C agonist
exifone [no description available]	3.23	1	0	benzophenones
mefloquine (-)-(11S,2'R)-erythro-mefloquine : An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (-)-(11S,2'R)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown.	4.22	2	0	[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol	antimalarial
triadimenol triadimenol : A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O1 by a 4-chlorophenyl group. A fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.	2.89	3	0	aromatic ether; conazole fungicide; hemiaminal ether; monochlorobenzenes; secondary alcohol; triazole fungicide	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; xenobiotic metabolite
nitazoxanide nitazoxanide: a 5-nitrothiazolyl derivative used for a broad range of intestinal parasitic infections including CRYPTOSPORIDIUM and GIARDIA; it is a redox-active nitrothiazolyl-salicylamide prodrug	3.23	1	0	benzamides; carboxylic ester
sufentanil Sufentanil: An opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent.. sufentanil : An anilide resulting from the formal condensation of the aryl amino group of 4-(methoxymethyl)-N-phenyl-1-[2-(2-thienyl)ethyl]piperidin-4-amine with propanoic acid.	3.23	1	0	anilide; ether; piperidines; thiophenes	anaesthesia adjuvant; intravenous anaesthetic; mu-opioid receptor agonist; opioid analgesic
acarbose [no description available]	3.23	1	0	tetrasaccharide derivative	EC 3.2.1.1 (alpha-amylase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; geroprotector; hypoglycemic agent
torsemide Torsemide: A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.. torasemide : An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.	3.23	1	0	aminopyridine; N-sulfonylurea; secondary amino compound	antihypertensive agent; loop diuretic
epirubicin Epirubicin: An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.	3.23	1	0	aminoglycoside; anthracycline antibiotic; anthracycline; deoxy hexoside; monosaccharide derivative; p-quinones; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	antimicrobial agent; antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
idarubicin Idarubicin: An orally administered anthracycline antineoplastic. The compound has shown activity against BREAST NEOPLASMS; LYMPHOMA; and LEUKEMIA.	3.6	2	0	anthracycline antibiotic; deoxy hexoside; monosaccharide derivative
piperacillin Piperacillin: Semisynthetic, broad-spectrum, AMPICILLIN derived ureidopenicillin antibiotic proposed for PSEUDOMONAS infections. It is also used in combination with other antibiotics.. piperacillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group.	3.61	2	0	penicillin allergen; penicillin	antibacterial drug
paroxetine Paroxetine: A serotonin uptake inhibitor that is effective in the treatment of depression.. paroxetine : A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3S,4R)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo.	3.61	2	0	aromatic ether; benzodioxoles; organofluorine compound; piperidines	antidepressant; anxiolytic drug; hepatotoxic agent; P450 inhibitor; serotonin uptake inhibitor
triciribine phosphate [no description available]	2.15	1	0
captopril Captopril: A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.. captopril : A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug.	3.23	1	0	alkanethiol; L-proline derivative; N-acylpyrrolidine; pyrrolidinemonocarboxylic acid	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
cefoperazone Cefoperazone: Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.. cefoperazone : A semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance.	3.23	1	0	cephalosporin	antibacterial drug
staurosporine [no description available]	2.06	1	0	indolocarbazole alkaloid; organic heterooctacyclic compound	apoptosis inducer; bacterial metabolite; EC 2.7.11.13 (protein kinase C) inhibitor; geroprotector
atracurium Atracurium: A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.. atracurium : A diester compound consisting of pentane-1,5-diol with both hydroxyls bearing 3-[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolinium-2(1H)-yl]propanoyl groups.	3.23	1	0	diester; quaternary ammonium ion	muscle relaxant; nicotinic antagonist
pergolide Pergolide: A long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.. pergolide : A diamine that is ergoline in which the beta-hydrogen at position 8 is replaced by a (methylthio)methyl group and the hydrogen attached to the piperidine nitrogen (position 6) is replaced by a propyl group. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used as the mesylate salt in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.	3.23	1	0	diamine; methyl sulfide; organic heterotetracyclic compound	antiparkinson drug; dopamine agonist
cefadroxil anhydrous Cefadroxil: Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.. cefadroxil : A cephalosporin bearing methyl and (2R)-2-amino-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.	3.23	1	0	cephalosporin	antibacterial drug
fialuridine [no description available]	3.23	1	0
amonafide xanafide: salt formulation of amonafide; DNA-intercalating agent and topoisomerase II inhibitor	2.89	3	0	isoquinolines
cefaclor anhydrous Cefaclor: Semisynthetic, broad-spectrum antibiotic derivative of CEPHALEXIN.. cefaclor : A cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton.	3.23	1	0	cephalosporin	antibacterial drug; drug allergen
alfentanil Alfentanil: A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.. alfentanil : A member of the class of piperidines that is piperidine having a 2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl group at the 1-position as well as N-phenylpropanamido- and methoxymethyl groups at the 4-position.	3.23	1	0	monocarboxylic acid amide; piperidines	central nervous system depressant; intravenous anaesthetic; mu-opioid receptor agonist; opioid analgesic; peripheral nervous system drug
miglustat miglustat: a glucosylceramide synthase inhibitor. miglustat : A hydroxypiperidine that is deoxynojirimycin in which the amino hydrogen is replaced by a butyl group.	3.23	1	0	piperidines; tertiary amino compound	anti-HIV agent; EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
haloperidol decanoate [no description available]	3.23	1	0	organic molecular entity
cefotetan Cefotetan: A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.. cefotetan : A semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of beta-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms.	3.23	1	0
lovastatin Lovastatin: A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.. lovastatin : A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).	3.23	1	0	delta-lactone; fatty acid ester; hexahydronaphthalenes; polyketide; statin (naturally occurring)	anticholesteremic drug; antineoplastic agent; Aspergillus metabolite; prodrug
flupirtine flupirtine: RN given refers to parent cpd without isomeric designation	2.89	3	0	aminopyridine
chaetochromin chaetochromin: from Chaetomium spp.; RN given refers to chaetochromin A	2.89	3	0
tolrestat tolrestat: RN & structure given in first source	3.23	1	0	naphthalenes	EC 1.1.1.21 (aldehyde reductase) inhibitor
enoximone Enoximone: A selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with CONGESTIVE HEART FAILURE.	2.89	3	0	aromatic ketone
simvastatin Simvastatin: A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.. simvastatin : A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.	5.08	4	0	delta-lactone; fatty acid ester; hexahydronaphthalenes; statin (semi-synthetic)	EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor; EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor; ferroptosis inducer; geroprotector; prodrug
balsalazide balsalazide: a mesalamine 5-aminosalicylate prodrug; 99% of ingested drug remains intact through the stomach and is delivered to and activated in the colon; used for inflammatory bowel disease, ulcerative colitis and radiation-induced proctosigmoiditis but avoided in patients with known hypersensitivity reaction to salicylates or mesalamine; structure in first source. balsalazide : A monohydroxybenzoic acid consisting of 5-aminosalicylic acid (mesalazine) linked to 4-aminobenzoyl-beta-alanine via an azo bond.	3.23	1	0
pravastatin Pravastatin: An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).. pravastatin : A carboxylic ester resulting from the formal condensation of (S)-2-methylbutyric acid with the hydroxy group adjacent to the ring junction of (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. Derived from microbial transformation of mevastatin, pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). The sodium salt is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.	3.23	1	0	3-hydroxy carboxylic acid; carbobicyclic compound; carboxylic ester; hydroxy monocarboxylic acid; secondary alcohol; statin (semi-synthetic)	anticholesteremic drug; environmental contaminant; metabolite; xenobiotic
cabergoline Cabergoline: An ergoline derivative and dopamine D2-agonist that inhibits PROLACTIN secretion. It is used in the management of HYPERPROLACTINEMIA, and to suppress lactation following childbirth for medical reasons. Cabergoline is also used in the management of PARKINSON DISEASE.. cabergoline : An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.	3.23	1	0	N-acylurea	antineoplastic agent; antiparkinson drug; dopamine agonist
atomoxetine atomoxetine : A secondary amino compound having methyl and 3-(2-methylphenoxy)-3-phenylpropan-1-yl substituents.	3.23	1	0	aromatic ether; secondary amino compound; toluenes	adrenergic uptake inhibitor; antidepressant; environmental contaminant; xenobiotic
quinapril Quinapril: A tetrahydroisoquinoline derivative and ANGIOTENSIN CONVERTING ENZYME inhibitor that is used in the treatment of HYPERTENSION and HEART FAILURE.. quinapril : A member of the class of isoquinolines that is (3S)-2-L-alanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid in which the alpha-amino group of the alanyl residue has been substituted by a 1-ethoxycarbonyl-4-phenylbutan-2-yl group (the all-S isomer). A prodrug for quinaprilat (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) used (generally as the hydrochloride salt) for the treatment of hypertension and congestive heart failure.	3.23	1	0	dicarboxylic acid monoester; ethyl ester; isoquinolines; tertiary carboxamide	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; prodrug
alpidem [no description available]	3.23	1	0	imidazoles
mifepristone Mifepristone: A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.	3.23	1	0	3-oxo-Delta(4) steroid; acetylenic compound; tertiary amino compound	abortifacient; contraceptive drug; hormone antagonist; synthetic oral contraceptive
itraconazole Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.. itraconazole : An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis.	2.08	1	0	aromatic ether; conazole antifungal drug; cyclic ketal; dichlorobenzene; dioxolane; N-arylpiperazine; triazole antifungal drug; triazoles	EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor; Hedgehog signaling pathway inhibitor; P450 inhibitor
fosphenytoin fosphenytoin: structure given in first & second source	3.23	1	0	imidazolidine-2,4-dione
pravadoline [no description available]	2.08	1	0
ranolazine Ranolazine: An acetanilide and piperazine derivative that functions as a SODIUM CHANNEL BLOCKER and prevents the release of enzymes during MYOCARDIAL ISCHEMIA. It is used in the treatment of ANGINA PECTORIS.. N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide : An aromatic amide obtained by formal condensation of the carboxy group of 2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetic acid with the amino group of 2,6-dimethylaniline.. ranolazine : A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.	3.23	1	0	aromatic amide; monocarboxylic acid amide; monomethoxybenzene; N-alkylpiperazine; secondary alcohol
finasteride Finasteride: An orally active 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE inhibitor. It is used as a surgical alternative for treatment of benign PROSTATIC HYPERPLASIA.. finasteride : An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.	3.23	1	0	3-oxo steroid; aza-steroid; delta-lactam	androgen antagonist; antihyperplasia drug; EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
esmolol methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate : A methyl ester that is methyl 3-(4-hydroxyphenyl)propanoate in which the hydrogen attached to the phenolic hydroxy group is substituted by a 2-hydroxy-3-(isopropylamino)propyl group.. esmolol : A racemate comprising equimolar amounts of (R)- and (S)-esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. While the S enantiomer possesses all of the heart rate control, both enantiomers contribute to lowering blood pressure.	3.23	1	0	aromatic ether; ethanolamines; methyl ester; secondary alcohol; secondary amino compound
sertindole sertindole : A phenylindole that is 1H-indole which is substituted on the nitrogen by a p-chlorophenyl group, at position 5 by chlorine, and at position 3 by a piperidin-4-yl group, which is itself substituted on the nitrogen by a 2-(2-oxoimidazolidin-1-yl)ethyl group.	2.08	1	0	heteroarylpiperidine; imidazolidinone; organochlorine compound; organofluorine compound; phenylindole	alpha-adrenergic antagonist; H1-receptor antagonist; second generation antipsychotic; serotonergic antagonist
adefovir adefovir: inhibitor of African swine fever virus. adefovir(1-) : A organophosphonate oxoanion obtained by removal of a proton from the phosphonate group of adefovir, a nucleoside reverse transcriptase inhibitor. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).. adefovir : A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection.	3.23	1	0	6-aminopurines; ether; phosphonic acids	antiviral drug; DNA synthesis inhibitor; drug metabolite; HIV-1 reverse transcriptase inhibitor; nephrotoxic agent
aromasil [no description available]	3.23	1	0	17-oxo steroid; 3-oxo-Delta(1),Delta(4)-steroid	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor; environmental contaminant; xenobiotic
sparfloxacin [no description available]	2.08	1	0	fluoroquinolone antibiotic; N-arylpiperazine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone
zileuton [no description available]	3.61	2	0	1-benzothiophenes; ureas	anti-asthmatic drug; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; ferroptosis inhibitor; leukotriene antagonist; non-steroidal anti-inflammatory drug
niguldipine [no description available]	2.08	1	0	diarylmethane
clopidogrel Clopidogrel: A ticlopidine analog and platelet purinergic P2Y receptor antagonist that inhibits adenosine diphosphate-mediated PLATELET AGGREGATION. It is used to prevent THROMBOEMBOLISM in patients with ARTERIAL OCCLUSIVE DISEASES; MYOCARDIAL INFARCTION; STROKE; or ATRIAL FIBRILLATION.. clopidogrel : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group, the methylene hydrogen of which is replaced by a methoxycarbonyl group (the S enantiomer). A P2Y12 receptor antagonist, it is used to inhibit blood clots and prevent heart attacks.	3.66	2	0	methyl ester; monochlorobenzenes; thienopyridine	anticoagulant; P2Y12 receptor antagonist; platelet aggregation inhibitor
cidofovir anhydrous Cidofovir: An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.. cidofovir anhydrous : Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.	3.23	1	0	phosphonic acids; pyrimidone	anti-HIV agent; antineoplastic agent; antiviral drug; photosensitizing agent
tiagabine Tiagabine: A nipecotic acid derivative that acts as a GABA uptake inhibitor and anticonvulsant agent. It is used in the treatment of EPILEPSY, for refractory PARTIAL SEIZURES.. tiagabine : A piperidinemonocarboxylic acid that is (R)-nipecotic acid in which the hydrogen attached to the nitrogen has been replaced by a 1,1-bis(3-methyl-2-thienyl)but-1-en-4-yl group. A GABA reuptake inhibitor, it is used (generally as the hydrochloride salt) for the treatment of epilepsy.	3.23	1	0	beta-amino acid; piperidinemonocarboxylic acid; tertiary amino compound; thiophenes	anticonvulsant; GABA reuptake inhibitor
mibefradil Mibefradil: A benzimidazoyl-substituted tetraline that selectively binds and inhibits CALCIUM CHANNELS, T-TYPE.	2.08	1	0	tetralins	T-type calcium channel blocker
topotecan Topotecan: An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.. topotecan : A pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks.	3.61	2	0	pyranoindolizinoquinoline	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor
eliprodil 1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol : A member of the class of piperidines that is piperidine substituted by a 2-(4-chlorophenyl)-2-hydroxyethyl group at position 1 and by a 4-fluorobenzyl group at position 4.	2.08	1	0	monochlorobenzenes; monofluorobenzenes; piperidines; secondary alcohol; tertiary amino compound
bromfenac bromfenac: bromfenac sodium is the active cpd; structure in first source. bromfenac : Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure.	3.23	1	0	aromatic amino acid; benzophenones; organobromine compound; substituted aniline	non-narcotic analgesic; non-steroidal anti-inflammatory drug
gemcitabine gemcitabine : A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.	3.61	2	0	organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; environmental contaminant; immunosuppressive agent; photosensitizing agent; prodrug; radiosensitizing agent; xenobiotic
ibutilide ibutilide: RN & structure in first source; RN refers to the fumarate salt	3.61	2	0	benzenes; organic amino compound
aripiprazole Aripiprazole: A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.. aripiprazole : An N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders.	4.19	4	0	aromatic ether; delta-lactam; dichlorobenzene; N-alkylpiperazine; N-arylpiperazine; quinolone	drug metabolite; H1-receptor antagonist; second generation antipsychotic; serotonergic agonist
remifentanil Remifentanil: A piperidine-propionate derivative and opioid analgesic structurally related to FENTANYL. It functions as a short-acting MU OPIOID RECEPTOR agonist, and is used as an analgesic during induction or maintenance of general anesthesia, following surgery, during childbirth, and in mechanically ventilated patients under intensive care.. remifentanil : A piperidinecarboxylate ester that is methyl piperidine-4-carboxylate in which the hydrogen attached to the nitrogen is substituted by a 3-methoxy-3-oxopropyl group and the hydrogen at position 4 is substituted the nitrogen of N-propanoylaniline.	3.23	1	0	alpha-amino acid ester; anilide; monocarboxylic acid amide; piperidinecarboxylate ester	intravenous anaesthetic; mu-opioid receptor agonist; opioid analgesic; sedative
atorvastatin [no description available]	4.73	4	0	aromatic amide; dihydroxy monocarboxylic acid; monofluorobenzenes; pyrroles; statin (synthetic)	environmental contaminant; xenobiotic
lamivudine [no description available]	3.61	2	0	monothioacetal; nucleoside analogue; oxacycle; primary alcohol	allergen; anti-HBV agent; antiviral drug; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor; HIV-1 reverse transcriptase inhibitor; prodrug
duloxetine [no description available]	3.61	2	0	duloxetine
irinotecan [no description available]	3.59	2	0	carbamate ester; delta-lactone; N-acylpiperidine; pyranoindolizinoquinoline; ring assembly; tertiary alcohol; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 5.99.1.2 (DNA topoisomerase) inhibitor; prodrug
valsartan Valsartan: A tetrazole derivative and ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to treat HYPERTENSION.. valsartan : A monocarboxylic acid amide consisting of L-valine in which the amino hydrogens have been replaced by a pentanoyl and a [2'-(1H-tetrazol-5-yl)biphenyl]-4-yl]methyl group. It exhibits antihypertensive activity.	3.23	1	0	biphenylyltetrazole; monocarboxylic acid amide; monocarboxylic acid	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
ibandronic acid Ibandronic Acid: Aminobisphosphonate that is a potent inhibitor of BONE RESORPTION. It is used in the treatment of HYPERCALCEMIA associated with malignancy, for the prevention of fracture and bone complications in patients with breast cancer and bone metastases, and for the treatment and prevention of POSTMENOPAUSAL OSTEOPOROSIS.	3.23	1	0
ziprasidone ziprasidone: a benzisothiazoylpiperazine derivative; has combined dopamine and serotonin receptor antagonist activity; structurally related to tiospirone. ziprasidone : A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.	3.23	1	0	1,2-benzisothiazole; indolones; organochlorine compound; piperazines	antipsychotic agent; dopaminergic antagonist; histamine antagonist; muscarinic antagonist; psychotropic drug; serotonergic antagonist
zolmitriptan zolmitriptan: an antimigraine compound; a serotonin (5HT)-1D receptor agonist. zolmitriptan : A member of the class of tryptamines that is N,N-dimethyltryptamine in which the hydrogen at position 5 of the indole ring has been replaced by a [(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl group. A serotonin 5-HT1 B and D receptor agonist, it is used for the treatment of migraine.	3.23	1	0	oxazolidinone; tryptamines	anti-inflammatory drug; serotonergic agonist; vasoconstrictor agent
emtricitabine Emtricitabine: A deoxycytidine analog and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B viruses. It is used to treat HIV INFECTIONS.. emtricitabine : An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection.	3.23	1	0	monothioacetal; nucleoside analogue; organofluorine compound; pyrimidone	antiviral drug; HIV-1 reverse transcriptase inhibitor
tasosartan tasosartan: angiotensin II antagonist; structure given in first source	3.23	1	0	biphenyls
tiludronic acid tiludronic acid: a bone resorption inhibitor; an antihypercalcemic agent; used in the tratment of Paget's disease; used in the treatment and prevention of osteoporosis; structure given in first source	3.23	1	0	organochlorine compound
tirofiban Tirofiban: Tyrosine analog and PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX antagonist that inhibits PLATELET AGGREGATION and is used in the treatment of ACUTE CORONARY SYNDROME.. tirofiban : A member of the class of piperidines that is L-tyrosine in which a hydrogen attached to the amino group is replaced by a butylsulfonyl group and in which the hydrogen attached to the phenolic hydroxy group is replaced by a 4-(piperidin-4-yl)butyl group.	3.23	1	0	L-tyrosine derivative; piperidines; sulfonamide	anticoagulant; fibrin modulating drug; platelet glycoprotein-IIb/IIIa receptor antagonist
capecitabine Capecitabine: A deoxycytidine derivative and fluorouracil PRODRUG that is used as an ANTINEOPLASTIC ANTIMETABOLITE in the treatment of COLON CANCER; BREAST CANCER and GASTRIC CANCER.. capecitabine : A carbamate ester that is cytidine in which the hydrogen at position 5 is replaced by fluorine and in which the amino group attached to position 4 is converted into its N-(penyloxy)carbonyl derivative. Capecitabine is a antineoplastic agent used in the treatment of cancers.	3.23	1	0	carbamate ester; cytidines; organofluorine compound	antimetabolite; antineoplastic agent; prodrug
adenosine quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit	3.89	3	0	adenosines; purines D-ribonucleoside	analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent
trovafloxacin trovafloxacin: a trifluoronaphthyridone derivative of 7-(3-azabicyclo(3.1.0)hexyl)naphthyridone; has antineoplastic activity. trovafloxacin : A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure.	3.23	1	0
verapamil hydrochloride verapamil hydrochloride : A racemate comprising equimolar amounts of dexverapamil hydrochloride and (S)-verapamil hydrochloride.	2.08	1	0
cefprozil [no description available]	3.23	1	0	cephalosporin; semisynthetic derivative	antibacterial drug
efavirenz efavirenz: HIV-1 reverse transcriptase inhibitor. efavirenz : 1,4-Dihydro-2H-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (S configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor with activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection.	4.66	4	0	acetylenic compound; benzoxazine; cyclopropanes; organochlorine compound; organofluorine compound	antiviral drug; HIV-1 reverse transcriptase inhibitor
nelfinavir Nelfinavir: A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.. nelfinavir : An aryl sulfide that is used (as its mesylate salt) for treatment of HIV and also exhibits some anticancer properties.	4.22	2	0	aryl sulfide; benzamides; organic heterobicyclic compound; phenols; secondary alcohol; tertiary amino compound	antineoplastic agent; HIV protease inhibitor
mevastatin mevastatin: antifungal metabolite from Penicillium brevicopactum; potent inhibitory activity to sterol synthesis; structure. mevastatin : A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals.	2.21	1	0	2-pyranones; carboxylic ester; hexahydronaphthalenes; polyketide; statin (naturally occurring)	antifungal agent; apoptosis inducer; EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor; fungal metabolite; Penicillium metabolite
fenofibric acid fenofibric acid: RN given refers to parent cpd without isomeric designation; structure. fenofibric acid : A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate.	3.23	1	0	aromatic ketone; chlorobenzophenone; monocarboxylic acid	drug metabolite; marine xenobiotic metabolite
thiazolyl blue thiazolyl blue: RN & II refers to bromide. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide : The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.	2.96	1	0	organic bromide salt	colorimetric reagent; dye
plerixafor plerixafor: a bicyclam derivate, highly potent & selective inhibitor of HIV-1 & HIV-2. plerixafor : An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.	4.08	4	0	azacycloalkane; azamacrocycle; benzenes; crown amine; secondary amino compound; tertiary amino compound	anti-HIV agent; antineoplastic agent; C-X-C chemokine receptor type 4 antagonist; immunological adjuvant
amprenavir [no description available]	4.22	2	0	carbamate ester; sulfonamide; tetrahydrofuryl ester	antiviral drug; HIV protease inhibitor
oseltamivir Oseltamivir: An acetamido cyclohexene that is a structural homolog of SIALIC ACID and inhibits NEURAMINIDASE.. oseltamivir : A cyclohexenecarboxylate ester that is the ethyl ester of oseltamivir acid. An antiviral prodrug (it is hydrolysed to the active free carboxylic acid in the liver), it is used to slow the spread of influenza.	3.23	1	0	acetamides; amino acid ester; cyclohexenecarboxylate ester; primary amino compound	antiviral drug; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; environmental contaminant; prodrug; xenobiotic
histamine phosphate histamine phosphate : A phosphate salt that is the diphosphate salt of histamine.	3.23	1	0	phosphate salt	histamine agonist
tilbroquinol [no description available]	3.23	1	0	organohalogen compound; quinolines
bendamustine [no description available]	3.61	2	0	benzimidazoles
aloxistatin aloxistatin: a membrane-permeable cysteine protease inhibitor. aloxistatin : An L-leucine derivative that is the amide obtained by formal condensation of the carboxy group of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid with the amino group of N-(3-methylbutyl)-L-leucinamide.	2.21	1	0	epoxide; ethyl ester; L-leucine derivative; monocarboxylic acid amide	anticoronaviral agent; cathepsin B inhibitor
droxicam droxicam: structure given in first source. droxicam : An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respectively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.	3.23	1	0	organic heterotricyclic compound; pyridines	cyclooxygenase 1 inhibitor; hepatotoxic agent; non-narcotic analgesic; non-steroidal anti-inflammatory drug; platelet aggregation inhibitor; prodrug
caroverine caroverine: structure	2.08	1	0	quinoxaline derivative
indocate [no description available]	2.89	3	0
ebrotidine ebrotidine: an H2-receptor antagonist and gastric mucosa protector	3.23	1	0	sulfonamide
cgs 9343b [no description available]	2.08	1	0	benzimidazoles
repaglinide [no description available]	3.23	1	0	piperidines
telmisartan Telmisartan: A biphenyl compound and benzimidazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION.. telmisartan : A member of the class of benzimidazoles used widely in the treatment of hypertension.	4.45	3	0	benzimidazoles; biphenyls; carboxybiphenyl	angiotensin receptor antagonist; antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; environmental contaminant; xenobiotic
inogatran inogatran: a direct low molecular weight thrombin inhibitor	2.21	1	0
2-methoxyestradiol 2-methoxy-17beta-estradiol : A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2.	2.08	1	0	17beta-hydroxy steroid; 3-hydroxy steroid	angiogenesis modulating agent; antimitotic; antineoplastic agent; human metabolite; metabolite; mouse metabolite
N(4)-acetylsulfathiazole N(4)-acetylsulfathiazole : A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 1,3-thiazol-2-yl group at the nitrogen atom. It is a metabolite of sulfathiazole.	2.89	3	0	1,3-thiazoles; acetamides; sulfonamide	marine xenobiotic metabolite
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.78	3	0	1,2,3-triazole
cyclizine hydrochloride [no description available]	2.59	2	0
2,3-trimethylene-4-quinazolone 2,3-trimethylene-4-quinazolone: structure in first source	2.89	3	0	quinazolines
fluorodeoxyglucose f18 Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)	2.47	2	0	2-deoxy-2-((18)F)fluoro-D-glucose; 2-deoxy-2-fluoro-aldehydo-D-glucose
sertraline Sertraline: A selective serotonin uptake inhibitor that is used in the treatment of depression.. sertraline : A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.	3.23	1	0	dichlorobenzene; secondary amino compound; tetralins	antidepressant; serotonin uptake inhibitor
zoledronic acid Zoledronic Acid: An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.. zoledronic acid : An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.	3.23	1	0	1,1-bis(phosphonic acid); imidazoles	bone density conservation agent
1,3-dimethyluric acid 1,3-dimethyluric acid : An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trionesubstituted by methyl groups at N-1 and N-3.	2.89	3	0	oxopurine	metabolite
acamprosate Acamprosate: Structural analog of taurine that is used for the prevention of relapse in individuals with ALCOHOLISM.. acamprosate : An organosulfonic acid that is propane-1-sulfonic acid substituted by an acetylamino group at position 3.	3.23	1	0	acetamides; organosulfonic acid	environmental contaminant; neurotransmitter agent; xenobiotic
isaxonine isaxonine: promotes nerve growth	3.23	1	0	aminopyrimidine
nebivolol 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol] : A member of the class of chromanes that is 2,2'-iminodiethanol in which one hydrogen attached to each hydroxy-bearing carbon is replaced by a 6-fluorochroman-2-yl group.	3.23	1	0	chromanes; diol; organofluorine compound; secondary alcohol; secondary amino compound
uk 68798 [no description available]	3.61	2	0	aromatic ether; sulfonamide; tertiary amino compound	anti-arrhythmia drug; potassium channel blocker
danofloxacin [no description available]	2.89	3	0	quinolines
hp 873 iloperidone: an atypical, negative symptom antipsychotic agent. iloperidone : A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia.	3.23	1	0	1,2-benzoxazoles; aromatic ether; aromatic ketone; methyl ketone; monoamine; organofluorine compound; piperidines; tertiary amino compound	dopaminergic antagonist; second generation antipsychotic; serotonergic antagonist
dexrazoxane Dexrazoxane: The (+)-enantiomorph of razoxane.	3.23	1	0	razoxane	antineoplastic agent; cardiovascular drug; chelator; immunosuppressive agent
fenoxypropazine [no description available]	3.23	1	0	aromatic ether
voriconazole Voriconazole: A triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.. voriconazole : A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4.	3.92	3	0	conazole antifungal drug; difluorobenzene; pyrimidines; tertiary alcohol; triazole antifungal drug	P450 inhibitor
aceclofenac [no description available]	3.23	1	0	amino acid; carboxylic ester; dichlorobenzene; monocarboxylic acid; secondary amino compound	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
nitrefazole [no description available]	4.19	4	0	imidazoles
alacepril [no description available]	2.08	1	0	dipeptide; thioacetate ester	EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
ubenimex ubenimex: growth inhibitor	2.08	1	0
methotrimeprazine Methotrimeprazine: A phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604). methotrimeprazine : A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively.	2.89	3	0	phenothiazines; tertiary amine	anticoronaviral agent; cholinergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; non-narcotic analgesic; phenothiazine antipsychotic drug; serotonergic antagonist
honokiol [no description available]	2.89	3	0	biphenyls
picropodophyllin picropodophyllin: isolated from American May apple (Podophyllum); inhibits IGF-I autophosphorylation without interfering with tyrosine kinase activity. picropodophyllotoxin : An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing 3,4,5-trimethoxyphenyl and hydroxy substituents.	2.15	1	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antineoplastic agent; insulin-like growth factor receptor 1 antagonist; plant metabolite; tyrosine kinase inhibitor
9-methoxyellipticine 9-methoxyellipticine: RN given refers to parent cpd	2.89	3	0
3-aminophenoxazone 3-aminophenoxazone: also inhibits sulfatase; structure	2.89	3	0	phenoxazine
tetrandrine tetrandrine: a bisbenzylisoquinoline that exhibits antifibrogenic activity	2.06	1	0	bisbenzylisoquinoline alkaloid; isoquinolines
3-deazaneplanocin 3-deazaneplanocin: S-adenosylhomocysteine hydrolase antagonist	2.89	3	0
doripenem Doripenem: A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.	3.58	2	0	carbapenems
tryptanthrine tryptanthrine: minor constituent of traditional Chinese medicine qing dai	2.89	3	0	alkaloid antibiotic; organic heterotetracyclic compound; organonitrogen heterocyclic compound
atovaquone Atovaquone: A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.. atovaquone : A naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position.	4.22	2	0	hydroxy-1,2-naphthoquinone
2-chlorodiazepam [no description available]	2.89	3	0
bendamustine hydrochloride [no description available]	2.1	1	0
Polycartine B [no description available]	2.89	3	0	phenazines
rivastigmine [no description available]	3.23	1	0	carbamate ester; tertiary amino compound	cholinergic drug; EC 3.1.1.8 (cholinesterase) inhibitor; neuroprotective agent
frovatriptan [no description available]	3.23	1	0	carbazoles
eletriptan eletriptan: 5-HT(1B/1D) receptor agonist; structure in first source. eletriptan : An N-alkylpyrrolidine, that is N-methylpyrrolidine in which the pro-R hydrogen at position 2 is replaced by a {5-[2-(phenylsulfonyl)ethyl]-1H-indol-3-yl}methyl group.	3.23	1	0	indoles; N-alkylpyrrolidine; sulfone	non-steroidal anti-inflammatory drug; serotonergic agonist; vasoconstrictor agent
rosiglitazone [no description available]	3.23	1	0	aminopyridine; thiazolidinediones	EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; insulin-sensitizing drug
aminoquinuride dihydrochloride [no description available]	2.89	3	0
bexarotene [no description available]	3.23	1	0	benzoic acids; naphthalenes; retinoid	antineoplastic agent
clarithromycin Clarithromycin: A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.. clarithromycin : The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.	3.23	1	0	macrolide antibiotic	antibacterial drug; environmental contaminant; protein synthesis inhibitor; xenobiotic
moexipril [no description available]	3.23	1	0	peptide
homocysteine Homocysteine: A thiol-containing amino acid formed by a demethylation of METHIONINE.. homocysteine : A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.. L-homocysteine : A homocysteine that has L configuration.	2.13	1	0	amino acid zwitterion; homocysteine; serine family amino acid	fundamental metabolite; mouse metabolite
gliquidone gliquidone: structure; RN given refers to parent cpd	2.25	1	0	isoquinolines
thioproperazine mesylate [no description available]	2.89	3	0	phenothiazines
n(6)-(delta(2)-isopentenyl)adenine N(6)-dimethylallyladenine : A 6-isopentenylaminopurine in which has the isopentenyl double bond is located between the 2 and 3 positions of the isopentenyl group.	2.89	3	0	6-isopentenylaminopurine	cytokinin
mci 9038 [no description available]	3.23	1	0	peptide
lopinavir [no description available]	3.51	1	0	amphetamines; dicarboxylic acid diamide	anticoronaviral agent; antiviral drug; HIV protease inhibitor
firefly luciferin Firefly Luciferin: A benzothaizole which is oxidized by LUCIFERASES, FIREFLY to cause emission of light (LUMINESCENCE).. Photinus luciferin : A 1,3-thiazolemonocarboxylic acid consisting of 3,5-dihydrothiophene-4-carboxylic acid having a 6-hydroxybenzothiazol-2-yl group at the 2-position.	2.08	1	0	1,3-thiazolemonocarboxylic acid; benzothiazoles; imidothioate	luciferin
4-methyl-N-(phenylmethyl)benzenesulfonamide [no description available]	2.89	3	0	sulfonamide
zpck ZPCK: alkylates histidine residue at active center of bovine chymotrypsin	2.63	2	0
p-methoxy-n-methylphenethylamine p-Methoxy-N-methylphenethylamine: A potent mast cell degranulator. It is involved in histamine release.. N,O-dimethyltyramine : A secondary amino compound that is tyramine in which the hydrogen of the phenolic hydroxy group has been replaced by a methyl group.	2.07	1	0	aromatic ether; secondary amino compound	metabolite
fulvestrant Fulvestrant: An estradiol derivative and estrogen receptor antagonist that is used for the treatment of estrogen receptor-positive, locally advanced or metastatic breast cancer.. fulvestrant : A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.	3.23	1	0	17beta-hydroxy steroid; 3-hydroxy steroid; organofluorine compound; sulfoxide	antineoplastic agent; estrogen antagonist; estrogen receptor antagonist
mafosfamide mafosfamide: RN given refers to cis-(+-)-isomer	2.1	1	0
sr141716 [no description available]	2.89	3	0	amidopiperidine; carbohydrazide; dichlorobenzene; monochlorobenzenes; pyrazoles	anti-obesity agent; appetite depressant; CB1 receptor antagonist
bosentan anhydrous Bosentan: A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.	3.23	1	0	primary alcohol; pyrimidines; sulfonamide	antihypertensive agent; endothelin receptor antagonist
paxilline paxilline: structure given in first source; RN given refers to (2R-(2alpha,4bbeta,6aalpha,12bbeta,12calpha,14abeta))-isomer. paxilline : An indole diterpene alkaloid with formula C27H33NO4 isolated from Penicillium paxilli. It is a potent inhibitor of large conductance Ca2(+)- and voltage-activated K(+) (BK)-type channels.	2.13	1	0	diterpene alkaloid; enone; organic heterohexacyclic compound; terpenoid indole alkaloid; tertiary alcohol	anticonvulsant; Aspergillus metabolite; EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor; genotoxin; geroprotector; mycotoxin; Penicillium metabolite; potassium channel blocker
vinpocetine [no description available]	2.08	1	0
(6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide [no description available]	2.59	2	0	aromatic ketone
perindopril Perindopril: An angiotensin-converting enzyme inhibitor. It is used in patients with hypertension and heart failure.. perindopril : An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline	3.23	1	0	alpha-amino acid ester; dicarboxylic acid monoester; ethyl ester; organic heterobicyclic compound	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
deguelin deguelin: a natural product from Mundulea sericea; RN refers to (7aS-cis)-isomer; structure given in first source. deguelin : A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers.	2.08	1	0	aromatic ether; diether; organic heteropentacyclic compound; rotenones	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor; plant metabolite
fingolimod fingolimod : An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate.	4.23	4	0	aminodiol; primary amino compound	antineoplastic agent; CB1 receptor antagonist; immunosuppressive agent; prodrug; sphingosine-1-phosphate receptor agonist
triptolide [no description available]	2.08	1	0	diterpenoid; epoxide; gamma-lactam; organic heteroheptacyclic compound	antispermatogenic agent; plant metabolite
tryptoquivaline tryptoquivaline: tremor-producing metabolite from Aspergillus clavatus; tetrapeptide derived from tryptophan, anthranilic acid, valine, & methylalanine; structure & N1 names previously assigned to tryptoquivaline C & tryptoquivaline D found to be incorrect & are revised in third source; see also record for tryptoquivalone; structure in third source	2.05	1	0
tesmilifene [no description available]	2.89	3	0	diarylmethane
deoxyglucose Deoxyglucose: 2-Deoxy-D-arabino-hexose. An antimetabolite of glucose with antiviral activity.. deoxyglucose : A deoxyhexose comprising glucose having at least one hydroxy group replaced by hydrogen.	2.07	1	0
tadalafil [no description available]	3.23	1	0	benzodioxoles; pyrazinopyridoindole	EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor; vasodilator agent
1-phenyl-2-decanoylamino-3-morpholino-1-propanol RV 538: noninactivating inhibitor of ceramide-UDPG glucosyltransferase; RN given for unspecified HCl; structure given in first source	2.06	1	0
paliperidone 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one : A member of the class of pyridopyrimidines that is 9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.. paliperidone : A racemate comprising equimolar amounts of (R)- and (S)-paliperidone. Paliperidone is the primary active metabolite of the older antipsychotic risperidone and is used for treatment of schizophrenia.	3.61	2	0	1,2-benzoxazoles; heteroarylpiperidine; organofluorine compound; pyridopyrimidine; secondary alcohol
nitisinone [no description available]	3.23	1	0	(trifluoromethyl)benzenes; C-nitro compound; cyclohexanones; mesotrione	EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
clofarabine [no description available]	3.23	1	0	adenosines; organofluorine compound	antimetabolite; antineoplastic agent
sr 48692 SR 48692: structure in first source; a neurotensin receptor-1 antagonist	2.08	1	0	N-acyl-amino acid
elacridar Elacridar: inhibitor of MDR1 PROTEIN; structure given in first source	3.66	2	0
pramipexole Pramipexole: A benzothiazole derivative and dopamine agonist with antioxidant properties that is used in the treatment of PARKINSON DISEASE and RESTLESS LEGS SYNDROME.. pramipexole : A member of the class of benzothiazoles that is 4,5,6,7-tetrahydro-1,3-benzothiazole in which the hydrogens at the 2 and 6-pro-S-positions are substituted by amino and propylamino groups, respectively.	3.23	1	0	benzothiazoles; diamine	antidyskinesia agent; antiparkinson drug; dopamine agonist; radical scavenger
valdecoxib [no description available]	3.23	1	0	isoxazoles; sulfonamide	antipyretic; antirheumatic drug; cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
sr 27897 SR 27897: structure given in first source; a CCK(A) receptor antagonist	2.89	3	0	indolyl carboxylic acid
imatinib mesylate imatinib methanesulfonate : A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.	24.16	734	91	methanesulfonate salt	anticoronaviral agent; antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
almotriptan almotriptan : An indole compound having a 2-(dimethylamino)ethyl group at the 3-position and a (pyrrolidin-1-ylsulfonyl)methyl group at the 5-position.	3.23	1	0	indoles; sulfonamide; tertiary amine	non-steroidal anti-inflammatory drug; serotonergic agonist; vasoconstrictor agent
gefitinib [no description available]	7.94	17	0	aromatic ether; monochlorobenzenes; monofluorobenzenes; morpholines; quinazolines; secondary amino compound; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine N-(N-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine: inhibits calcium-activated neutral protease; see also record for E-64; RN given refers to (2-S-(2alpha,3beta)(R*)-isomer)	2.89	3	0	leucine derivative
bay x 1005 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid: inhibits synthesis of leukotriene B4 and 5-hydroxyeicosatetraenoic acid; inhibits five-lipoxygenase activating protein(FLAP)and leukotriene A4 hydrolase(LTA4H); structure given in first source;	2.08	1	0
norketamine norketamine: metabolite of ketamine; RN given refers to cpd without isomeric designation	2.89	3	0	organochlorine compound
desloratadine desloratadine: major metabolite of loratadine. desloratadine : Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.	3.23	1	0	benzocycloheptapyridine	anti-allergic agent; cholinergic antagonist; drug metabolite; H1-receptor antagonist
desvenlafaxine O-desmethylvenlafaxine : A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-hydroxyphenyl group. It is a metabolite of the drug venlafaxine.	3.23	1	0	cyclohexanols; phenols; tertiary amino compound	antidepressant; drug metabolite; marine xenobiotic metabolite
indatraline indatraline: RN given for (trans)-isomer; structure in first source	2.63	2	0	indanes
lestaurtinib [no description available]	4.82	5	0	indolocarbazole
gyki 53655 GYKI 53655: an AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate) receptor antagonist	2.08	1	0
methotrexate [no description available]	4.47	6	0	dicarboxylic acid; monocarboxylic acid amide; pteridines	abortifacient; antimetabolite; antineoplastic agent; antirheumatic drug; dermatologic drug; DNA synthesis inhibitor; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; immunosuppressive agent
salvinorin a salvinorin A: from the herb, Salvia divinorum	2.21	1	0	organic heterotricyclic compound; organooxygen compound	metabolite; oneirogen
tamsulosin [no description available]	3.23	1	0	5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide	alpha-adrenergic antagonist; antineoplastic agent
rufinamide rufinamide: for treatment of Lennox-Gastaut syndrome; structure in first source	3.23	1	0	aromatic amide; heteroarene
olmesartan medoxomil Olmesartan Medoxomil: An ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to manage HYPERTENSION.	3.23	1	0	biphenyls
dexpanthenol dexpanthenol: The alcohol of pantothenic acid	3.23	1	0	amino alcohol; monocarboxylic acid amide	cholinergic drug; provitamin
fosamprenavir fosamprenavir: a prodrug of the protease inhibitor amprenavir. fosamprenavir : A sulfonamide with a structure based on that of sulfanilamide substituted on the sulfonamide nitrogen by a (2R,3S)-4-phenyl-2-(phosphonooxy)-3-({[(3S)-tetrahydrofuran-3-yloxy]carbonyl}amino)butyl group. It is a pro-drug of the HIV protease inhibitor and antiretroviral drug amprenavir.	3.23	1	0	sulfonamide	prodrug
4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide 4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide: increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol	2.89	3	0
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide: binds with high affinity to glial mitochondrial diazepam binding inhibitor receptors & increases mitochondrial steroidogenesis	2.89	3	0	phenylindole
abiraterone [no description available]	2.54	2	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; pyridines	antineoplastic agent; EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
ml-3000 [no description available]	2.08	1	0
l 741626 3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole: structure in first source	2.89	3	0	piperidines
febuxostat Febuxostat: A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.. febuxostat : A 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout.	4.54	3	0	1,3-thiazolemonocarboxylic acid; aromatic ether; nitrile	EC 1.17.3.2 (xanthine oxidase) inhibitor
carbapenems [no description available]	2.04	1	0
cd 437 CD 437: selective for retinoic acid receptors gamma. CD437 : A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)gamma and induces cell cycle arrest and apoptosis in various cancer cells.	2.08	1	0	adamantanes; monocarboxylic acid; naphthoic acid; phenols	apoptosis inducer; retinoic acid receptor gamma agonist
proline Proline: A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.. proline : An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.	2.31	1	0	amino acid zwitterion; glutamine family amino acid; L-alpha-amino acid; proline; proteinogenic amino acid	algal metabolite; compatible osmolytes; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
escitalopram Escitalopram: S-enantiomer of CITALOPRAM. Belongs to a class of drugs known as SELECTIVE SEROTONIN REUPTAKE INHIBITORS, used to treat depression and generalized anxiety disorder.. escitalopram : A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has S-configuration at the chiral centre. It is the active enantiomer of citalopram.	3.23	1	0	1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile	antidepressant; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
10-propargyl-10-deazaaminopterin 10-propargyl-10-deazaaminopterin: structure in first source. pralatrexate : A pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma.	3.23	1	0	N-acyl-L-glutamic acid; pteridines; terminal acetylenic compound	antimetabolite; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
docetaxel anhydrous Docetaxel: A semisynthetic analog of PACLITAXEL used in the treatment of locally advanced or metastatic BREAST NEOPLASMS and NON-SMALL CELL LUNG CANCER.. docetaxel anhydrous : A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.	3.61	2	0	secondary alpha-hydroxy ketone; tetracyclic diterpenoid	antimalarial; antineoplastic agent; photosensitizing agent
perifosine [no description available]	2.52	2	0	ammonium betaine; phospholipid	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
atazanavir atazanavir : A heavily substituted carbohydrazide that is an antiretroviral drug of the protease inhibitor (PI) class used to treat infection of human immunodeficiency virus (HIV).	4.22	2	0	carbohydrazide	antiviral drug; HIV protease inhibitor
levofloxacin Levofloxacin: The L-isomer of Ofloxacin.. levofloxacin : An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase.	3.23	1	0	9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid; fluoroquinolone antibiotic; quinolone antibiotic	antibacterial drug; DNA synthesis inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; topoisomerase IV inhibitor
ezetimibe Ezetimibe: An azetidine derivative and ANTICHOLESTEREMIC AGENT that inhibits intestinal STEROL absorption. It is used to reduce total CHOLESTEROL; LDL CHOLESTEROL, and APOLIPOPROTEINS B in the treatment of HYPERLIPIDEMIAS.. ezetimibe : A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer).	3.65	2	0	azetidines; beta-lactam; organofluorine compound	anticholesteremic drug; antilipemic drug; antimetabolite
ertapenem Ertapenem: A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of Gram-positive and Gram-negative bacterial infections including intra-abdominal infections, acute gynecological infections, complicated urinary tract infections, skin infections, and respiratory tract infections. It is also used to prevent infection in colorectal surgery.. ertapenem : Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract.	3.23	1	0	carbapenemcarboxylic acid; pyrrolidinecarboxamide	antibacterial drug
dx 8951 [no description available]	2.89	3	0	pyranoindolizinoquinoline
cox 189 lumiracoxib: a COX-2 inhibitor. lumiracoxib : An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity.	3.23	1	0	amino acid; monocarboxylic acid; organochlorine compound; organofluorine compound; secondary amino compound	cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
conivaptan conivaptan : The amide resulting from the formal condensation of 4-[(biphenyl-2-ylcarbonyl)amino]benzoic acid with the benzazepine nitrogen of 2-methyl-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepine. It is an antagonist for two of the three types of arginine vasopressin (AVP) receptors, V1a and V2. It is used as its hydrochloride salt for the treatment of hyponatraemia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH).	3.23	1	0	benzazepine	aquaretic; vasopressin receptor antagonist
mk 767 5-((2,4-dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide: an antihyperlipidemic agent that also functions as an insulin sensitizer, PPARalpha agonist, and PPARgamma agonist; structure in first source	2.08	1	0
vatalanib [no description available]	3.86	3	0	monochlorobenzenes; phthalazines; pyridines; secondary amino compound	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist
moxifloxacin Moxifloxacin: A fluoroquinolone that acts as an inhibitor of DNA TOPOISOMERASE II and is used as a broad-spectrum antibacterial agent.. moxifloxacin : A quinolone that consists of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid bearing a cyclopropyl substituent at position 1, a fluoro substitiuent at position 6, a (4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl group at position 7 and a methoxy substituent at position 8. A member of the fluoroquinolone class of antibacterial agents.	3.61	2	0	aromatic ether; cyclopropanes; fluoroquinolone antibiotic; pyrrolidinopiperidine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone	antibacterial drug
pralnacasan pralnacasan: NSAID, ICE inhibitor & metastasis inhibitor; RN & structure in first source	3.23	1	0
clevidipine clevidipine: a calcium channel blocker and antihypertensive agent; structure in first source	3.23	1	0	dihydropyridine
ruboxistaurin ruboxistaurin: inhibits protein kinase C beta; structure in first source	2.5	2	0
solifenacin [no description available]	3.61	2	0	isoquinolines
dexmethylphenidate dexmethylphenidate : A methyl phenyl(piperidin-2-yl)acetate in which both stereocentres have R configuration. It is the active enantiomer in the racemic drug methylphenidate.	3.23	1	0	methyl phenyl(piperidin-2-yl)acetate	adrenergic agent
bazedoxifene acetate [no description available]	2.08	1	0
naproxen Naproxen: An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.. naproxen : A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes.	3.23	1	0	methoxynaphthalene; monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; gout suppressant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
canertinib [no description available]	3.04	4	0	monochlorobenzenes; morpholines; organofluorine compound; quinazolines	antineoplastic agent; tyrosine kinase inhibitor
cinacalcet cinacalcet : A secondary amino compound that is (1R)-1-(naphthalen-1-yl)ethanamine in which one of the hydrogens attached to the nitrogen is substituted by a 3-[3-(trifluoromethyl)phenyl]propyl group.	3.23	1	0	(trifluoromethyl)benzenes; naphthalenes; secondary amino compound	calcimimetic; P450 inhibitor
birb 796 [no description available]	4.3	5	0	aromatic ether; morpholines; naphthalenes; pyrazoles; ureas	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; immunomodulator
lubiprostone [no description available]	3.23	1	0
telbivudine [no description available]	3.61	2	0	pyrimidine 2'-deoxyribonucleoside	antiviral drug; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
tipifarnib [no description available]	3.07	4	0	imidazoles; monochlorobenzenes; primary amino compound; quinolone	antineoplastic agent; apoptosis inducer; EC 2.5.1.58 (protein farnesyltransferase) inhibitor
cyc 202 seliciclib : 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.	4.68	7	0	2,6-diaminopurines	antiviral drug; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
paromomycin Paromomycin: An aminoglycoside antibacterial and antiprotozoal agent produced by species of STREPTOMYCES.. paromomycin : An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis.	3.23	1	0	amino cyclitol glycoside; aminoglycoside antibiotic	anthelminthic drug; antibacterial drug; antiparasitic agent; antiprotozoal drug
anidulafungin Anidulafungin: Echinocandin antifungal agent that is used in the treatment of CANDIDEMIA and CANDIDIASIS.. anidulafungin : A semisynthetic echinocandin anti-fungal drug. It is active against Aspergillus and Candida species and is used for the treatment of invasive candidiasis.	3.23	1	0	antibiotic antifungal drug; azamacrocycle; echinocandin; heterodetic cyclic peptide; semisynthetic derivative
avasimibe [no description available]	2.89	3	0	monoterpenoid
17 alpha-hydroxyprogesterone caproate 17 alpha-Hydroxyprogesterone Caproate: Hydroxyprogesterone derivative that acts as a PROGESTIN and is used to reduce the risk of recurrent MISCARRIAGE and of PREMATURE BIRTH. It is also used in combination with ESTROGEN in the management of MENSTRUATION DISORDERS.	3.23	1	0	corticosteroid hormone
varenicline Varenicline: A benzazepine derivative that functions as an ALPHA4-BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION.. varenicline : An organic heterotetracyclic compound that acts as a partial agonist for nicotinic cholinergic receptors and is used (in the form of its tartate salt) as an aid to giving up smoking.	3.23	1	0
angiotensin ii Giapreza: injectable form of angiotensin II used to increase blood pressure in adult patients with septic or other distributive shock. Ile(5)-angiotensin II : An angiotensin II that acts on the central nervous system (PDB entry: 1N9V).	2.06	1	0	amino acid zwitterion; angiotensin II	human metabolite
fiduxosin fiduxosin: fiduxosin (ABT-980) is the (3aR,9bR)-isomer; structure in first source	3.23	1	0
atropine tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate : A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.	3.23	1	0
sb 203580 [no description available]	5.12	7	0	imidazoles; monofluorobenzenes; pyridines; sulfoxide	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector; Hsp90 inhibitor; neuroprotective agent
enzastaurin [no description available]	2.78	3	0	indoles; maleimides
erlotinib [no description available]	6.04	10	0	aromatic ether; quinazolines; secondary amino compound; terminal acetylenic compound	antineoplastic agent; epidermal growth factor receptor antagonist; protein kinase inhibitor
erlotinib hydrochloride [no description available]	7.21	11	0	hydrochloride; terminal acetylenic compound	antineoplastic agent; protein kinase inhibitor
piboserod Serotonin 5-HT4 Receptor Antagonists: Drugs that bind to but do not activate SEROTONIN 5-HT4 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN RECEPTOR AGONISTS.	2.08	1	0
l 163191 [no description available]	3.07	4	0
dizocilpine [no description available]	2.89	3	0	secondary amino compound; tetracyclic antidepressant	anaesthetic; anticonvulsant; neuroprotective agent; nicotinic antagonist; NMDA receptor antagonist
bd 1047 N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin: sigma receptor ligand; putative sigma receptor antagonist with antidystonic activity	2.08	1	0	primary amine
s-benzylcysteine [no description available]	2.89	3	0	S-aryl-L-cysteine zwitterion
etravirine [no description available]	3.23	1	0	aminopyrimidine; aromatic ether; dinitrile; organobromine compound	antiviral agent; HIV-1 reverse transcriptase inhibitor
chelidonine chelidonine: benzophenanthridine derived from scoulerine from Chelidonium majus; RN given refers to parent cpd (chelidonine, (5bR-(5balpha,6beta,12alpha))-isomer)	2.89	3	0	alkaloid antibiotic; alkaloid fundamental parent; benzophenanthridine alkaloid
dronedarone Dronedarone: A non-iodinated derivative of amiodarone that is used for the treatment of ARRHYTHMIA.. dronedarone : A member of the class of 1-benzofurans used for the treatment of cardiac arrhythmias.	3.23	1	0	1-benzofurans; aromatic ether; aromatic ketone; sulfonamide; tertiary amino compound	anti-arrhythmia drug; environmental contaminant; xenobiotic
ramelteon ramelteon: melatonin MT1/MT2 receptor agonist	3.23	1	0	indanes
lapatinib [no description available]	8	21	0	furans; organochlorine compound; organofluorine compound; quinazolines	antineoplastic agent; tyrosine kinase inhibitor
darunavir Darunavir: An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.. darunavir : An N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors.	3.23	1	0	carbamate ester; furofuran; sulfonamide	antiviral drug; HIV protease inhibitor
deferasirox Deferasirox: A triazole and benzoate derivative that acts as a selective iron chelator. It is used in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion dependent THALASSEMIA.. deferasirox : A member of the class of triazoles, deferasirox is 1,2,4-triazole substituted by a 4-carboxyphenyl group at position 1 and by 2-hydroxyphenyl groups at positions 3 and 5. An orally active iron chelator, it is used to manage chronic iron overload in patients receiving long-term blood transfusions.	3.23	1	0	benzoic acids; monocarboxylic acid; phenols; triazoles	iron chelator
dabigatran Dabigatran: A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.. dabigatran : An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-beta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.	2.21	1	0	aromatic amide; benzimidazoles; beta-alanine derivative; carboxamidine; pyridines	anticoagulant; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; EC 3.4.21.5 (thrombin) inhibitor
tbc-11251 sitaxsentan: endothelin A receptor antagonist; structure in first source	3.23	1	0	benzodioxoles
tolvaptan [no description available]	3.23	1	0	benzazepine; benzenedicarboxamide	aquaretic; vasopressin receptor antagonist
sorafenib [no description available]	9.42	41	0	(trifluoromethyl)benzenes; aromatic ether; monochlorobenzenes; phenylureas; pyridinecarboxamide	angiogenesis inhibitor; anticoronaviral agent; antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; ferroptosis inducer; tyrosine kinase inhibitor
lenalidomide [no description available]	4.62	4	0	aromatic amine; dicarboximide; isoindoles; piperidones	angiogenesis inhibitor; antineoplastic agent; immunomodulator
N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide [no description available]	2.08	1	0	aminoquinoline
regadenoson [no description available]	3.23	1	0	purine nucleoside
roxindole [no description available]	2.89	3	0	indoles	alpha-adrenergic antagonist; serotonergic drug
sr 142806 [no description available]	2.08	1	0
lacosamide Lacosamide: An acetamide derivative that acts as a blocker of VOLTAGE-GATED SODIUM CHANNELS. It is used as an anticonvulsant, for adjunctive or monotherapy, in the treatment of PARTIAL SEIZURES.	3.23	1	0	N-acyl-amino acid
conidendrin [no description available]	2.89	3	0
vincaleukoblastine [no description available]	3.23	1	0	acetate ester; indole alkaloid fundamental parent; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; tertiary alcohol; tertiary amino compound; vinca alkaloid	antineoplastic agent; immunosuppressive agent; microtubule-destabilising agent; plant metabolite
Porfiromycine [no description available]	2.89	3	0	mitomycin
benzarone benzarone: antihemorrhagic agent; structure	3.23	1	0	1-benzofurans
estramustine Estramustine: A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.. estramustine : A carbamate ester obtained by the formal condensation of the hydroxy group of 17beta-estradiol with the carboxy group of bis(2-chloroethyl)carbamic acid.	3.23	1	0	17beta-hydroxy steroid; carbamate ester; organochlorine compound	alkylating agent; antineoplastic agent; radiation protective agent
arsenic trioxide [no description available]	3.41	1	0
nsc 95397 [no description available]	2.89	3	0	1,4-naphthoquinones
4-methyl-2-quinazolinamine 4-methyl-2-quinazolinamine: from Streptomyces of TCM plant; structure in first source	2.89	3	0
berbamine [no description available]	3.51	1	0	bisbenzylisoquinoline alkaloid; isoquinolines
2-glycineamide-5-chlorophenyl-2-pyrryl ketone [no description available]	2.89	3	0
homoharringtonine Homoharringtonine: Semisynthetic derivative of harringtonine that acts as a protein synthesis inhibitor and induces APOPTOSIS in tumor cells. It is used in the treatment of MYELOID LEUKEMIA, CHRONIC.. omacetaxine mepesuccinate : A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.	4.95	6	0	alkaloid ester; enol ether; organic heteropentacyclic compound; tertiary alcohol	anticoronaviral agent; antineoplastic agent; apoptosis inducer; protein synthesis inhibitor
elesclomol [no description available]	2.08	1	0	carbohydrazide; thiocarbonyl compound	antineoplastic agent; apoptosis inducer
wortmannin [no description available]	2.21	1	0	acetate ester; cyclic ketone; delta-lactone; organic heteropentacyclic compound	anticoronaviral agent; antineoplastic agent; autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector; Penicillium metabolite; radiosensitizing agent
niguldipine hydrochloride [no description available]	2.63	2	0
2,5-bis(5-hydroxymethyl-2-thienyl)furan [no description available]	2.89	3	0	thiophenes
nsc 663284 NSC 663284: structure in first source	2.08	1	0	quinolone
bortezomib [no description available]	5.32	9	0	amino acid amide; L-phenylalanine derivative; pyrazines	antineoplastic agent; antiprotozoal drug; protease inhibitor; proteasome inhibitor
ritonavir Ritonavir: An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV. It also inhibits CYTOCHROME P-450 CYP3A.. ritonavir : An L-valine derivative that is L-valinamide in which alpha-amino group has been acylated by a [(2-isopropyl-1,3-thiazol-4-yl)methyl]methylcarbamoyl group and in which a hydrogen of the carboxamide amino group has been replaced by a (2R,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. A CYP3A inhibitor and antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir. Also used in combination with dasabuvir sodium hydrate, ombitasvir and paritaprevir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver.	4.35	5	0	1,3-thiazoles; carbamate ester; carboxamide; L-valine derivative; ureas	antiviral drug; environmental contaminant; HIV protease inhibitor; xenobiotic
bardoxolone methyl methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate: structure in first source	2.53	2	0	cyclohexenones
tryptoquivaline fumitremorgin C : An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.	3.51	1	0	aromatic ether; indole alkaloid; organic heteropentacyclic compound	breast cancer resistance protein inhibitor; mycotoxin
nsc 23766 [no description available]	2.08	1	0	aminopyrimidine; aminoquinoline; primary amino compound; secondary amino compound; tertiary amino compound	antiviral agent; apoptosis inducer; EC 3.6.5.2 (small monomeric GTPase) inhibitor; muscarinic antagonist
leupeptins Leupeptins: A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins.	2.02	1	0
carboplatin [no description available]	2.1	1	0
Destruxin B [no description available]	2.89	3	0	cyclodepsipeptide
s-adenosylhomocysteine S-Adenosylhomocysteine: 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.. S-adenosyl-L-homocysteine : An organic sulfide that is the S-adenosyl derivative of L-homocysteine.	2.21	1	0	adenosines; amino acid zwitterion; homocysteine derivative; homocysteines; organic sulfide	cofactor; EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor; EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor; epitope; fundamental metabolite
n-acetylneuraminic acid N-Acetylneuraminic Acid: An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518). N-acetylneuraminic acid : An N-acylneuraminic acid where the N-acyl group is specified as acetyl.	3.47	1	1	N-acetylneuraminic acids	antioxidant; bacterial metabolite; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; human metabolite; mouse metabolite
oxytocin Oxytocin: A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.. oxytocin : A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour.	3.23	1	0	heterodetic cyclic peptide; peptide hormone	oxytocic; vasodilator agent
tosylphenylalanyl chloromethyl ketone Tosylphenylalanyl Chloromethyl Ketone: An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.. N-tosyl-L-phenylalanyl chloromethyl ketone : The N-tosyl derivative of L-phenylalanyl chloromethyl ketone.	2.89	3	0	alpha-chloroketone; sulfonamide	alkylating agent; serine proteinase inhibitor
pentostatin Pentostatin: A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.. pentostatin : A member of the class of coformycins that is coformycin in which the hydroxy group at position 2' is replaced with a hydrogen. It is a drug used for the treatment of hairy cell leukaemia.	3.58	2	0	coformycins	antimetabolite; antineoplastic agent; Aspergillus metabolite; bacterial metabolite; EC 3.5.4.4 (adenosine deaminase) inhibitor
quinidine Quinidine: An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.. quinidine : A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.	3.61	2	0	cinchona alkaloid	alpha-adrenergic antagonist; anti-arrhythmia drug; antimalarial; drug allergen; EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor; EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor; muscarinic antagonist; P450 inhibitor; potassium channel blocker; sodium channel blocker
meropenem Meropenem: A thienamycin derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of bacterial infections, including infections in immunocompromised patients.. meropenem : A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively.	3.23	1	0	alpha,beta-unsaturated monocarboxylic acid; carbapenemcarboxylic acid; organic sulfide; pyrrolidinecarboxamide	antibacterial agent; antibacterial drug; drug allergen
griseofulvin Griseofulvin: An antifungal agent used in the treatment of TINEA infections.. griseofulvin : An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.	3.23	1	0	1-benzofurans; antibiotic antifungal drug; benzofuran antifungal drug; organochlorine compound; oxaspiro compound	antibacterial agent; Penicillium metabolite
cefoxitin Cefoxitin: A semisynthetic cephamycin antibiotic resistant to beta-lactamase.. cefoxitin : A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase.	3.23	1	0	beta-lactam antibiotic allergen; cephalosporin; cephamycin; semisynthetic derivative	antibacterial drug
saquinavir Saquinavir: An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits CYTOCHROME P-450 CYP3A.. saquinavir : An aspartic acid derivative obtained by formal condensation of the primary amino group of (2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl]-3-hydroxy-1-phenylbutan-2-ylamine with the carboxy group of N(2)(-quinolin-2-ylcarbonyl)-L-asparagine. An inhibitor of HIV-1 protease.	4.69	4	0	L-asparagine derivative; quinolines	antiviral drug; HIV protease inhibitor
pancuronium Pancuronium: A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than CURARE but has less effect on the circulatory system and on histamine release.. pancuronium : A steroid ester in which a 5alpha-androstane skeleton is C-3alpha- and C-17beta-disubstituted with acetoxy groups and 2beta- and 16beta-disubstituted with 1-methylpiperidinium-1-yl groups. It is a non-depolarizing curare-mimetic muscle relaxant.	3.23	1	0	acetate ester; steroid ester	cholinergic antagonist; muscle relaxant; nicotinic antagonist
abacavir abacavir: a carbocyclic nucleoside with potent selective anti-HIV activity. abacavir : A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection.	4.22	2	0	2,6-diaminopurines	antiviral drug; drug allergen; HIV-1 reverse transcriptase inhibitor
miglitol [no description available]	3.23	1	0	piperidines
mometasone furoate Mometasone Furoate: A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.	2.21	1	0	11beta-hydroxy steroid; 2-furoate ester; 20-oxo steroid; 3-oxo-Delta(1),Delta(4)-steroid; organochlorine compound; steroid ester	anti-allergic agent; anti-inflammatory drug
metyrosine alpha-methyl-L-tyrosine : An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma.	3.23	1	0	L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	antihypertensive agent; EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
linezolid [no description available]	3.61	2	0	acetamides; morpholines; organofluorine compound; oxazolidinone	antibacterial drug; protein synthesis inhibitor
cyclopamine [no description available]	2.04	1	0	piperidines	glioma-associated oncogene inhibitor
6-prenylchrysin 6-prenylchrysin: structure in first source. 6-(3,3-dimethylallyl)chrysin : A dihydroxyflavone that is chrysin substituted by a prenyl group at position 6.	4.43	2	0	7-hydroxyflavonol; dihydroxyflavone
clindamycin phosphate [no description available]	3.23	1	0
eplerenone Eplerenone: A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.	3.23	1	0	3-oxo-Delta(4) steroid; epoxy steroid; gamma-lactone; methyl ester; organic heteropentacyclic compound; oxaspiro compound; steroid acid ester	aldosterone antagonist; antihypertensive agent
tolterodine [no description available]	3.23	1	0	tertiary amine	antispasmodic drug; muscarinic antagonist; muscle relaxant
darifenacin darifenacin : 2-[(3S)-1-Ethylpyrrolidin-3-yl]-2,2-diphenylacetamide in which one of the hydrogens at the 2-position of the ethyl group is substituted by a 2,3-dihydro-1-benzofuran-5-yl group. It is a selective antagonist for the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions, and is used as the hydrobromide salt in the management of urinary incontinence.	3.23	1	0	1-benzofurans; monocarboxylic acid amide; pyrrolidines	antispasmodic drug; muscarinic antagonist
trichostatin a trichostatin A: chelates zinc ion in the active site of histone deacetylases, resulting in preventing histone unpacking so DNA is less available for transcription; do not confuse with TRICHOSANTHIN which is a protein; found in STREPTOMYCES	2.21	1	0	antibiotic antifungal agent; hydroxamic acid; trichostatin	bacterial metabolite; EC 3.5.1.98 (histone deacetylase) inhibitor; geroprotector
tretinoin Tretinoin: An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).. retinoic acid : A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified).. all-trans-retinoic acid : A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.	4.11	2	0	retinoic acid; vitamin A	anti-inflammatory agent; antineoplastic agent; antioxidant; AP-1 antagonist; human metabolite; keratolytic drug; retinoic acid receptor agonist; retinoid X receptor agonist; signalling molecule
retinol Vitamin A: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.. vitamin A : Any member of a group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids that exhibit biological activity against vitamin A deficiency. Vitamin A is involved in immune function, vision, reproduction, and cellular communication.. all-trans-retinol : A retinol in which all four exocyclic double bonds have E- (trans-) geometry.. retinol : A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraen-1-ol substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified).	3.23	1	0	retinol; vitamin A	human metabolite; mouse metabolite; plant metabolite
tacrolimus Tacrolimus: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.. tacrolimus (anhydrous) : A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis.	4.54	3	0	macrolide lactam	bacterial metabolite; immunosuppressive agent
rosuvastatin rosuvastatin : A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer).	3.23	1	0	dihydroxy monocarboxylic acid; monofluorobenzenes; pyrimidines; statin (synthetic); sulfonamide	anti-inflammatory agent; antilipemic drug; cardioprotective agent; CETP inhibitor; environmental contaminant; xenobiotic
mycophenolic acid Mycophenolic Acid: Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.. mycophenolate : A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of mycophenolic acid.. mycophenolic acid : A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.	3.23	1	0	2-benzofurans; gamma-lactone; monocarboxylic acid; phenols	anticoronaviral agent; antimicrobial agent; antineoplastic agent; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; environmental contaminant; immunosuppressive agent; mycotoxin; Penicillium metabolite; xenobiotic
clindamycin Clindamycin: An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.. clindamycin : A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic.	3.23	1	0
fosfomycin Fosfomycin: An antibiotic produced by Streptomyces fradiae.. fosfomycin : A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus.	3.23	1	0	epoxide; phosphonic acids	antimicrobial agent; EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor
zithromax Azithromycin: A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.. azithromycin : A macrolide antibiotic useful for the treatment of bacterial infections.	3.23	1	0	macrolide antibiotic	antibacterial drug; environmental contaminant; xenobiotic
pd 173955 PD 173955: inhibits src family-selective tyrosine kinase; structure in first source	2.49	2	0	aryl sulfide; dichlorobenzene; methyl sulfide; pyridopyrimidine	tyrosine kinase inhibitor
pd 166326 PD 166326: a pyrido(2,3-d)pyrimidine src tyrosine kinase inhibitor	3.6	2	0
gw 3965 GW 3965: a liver X receptor ligand	2.08	1	0	diarylmethane
y 27632 Y 27632: RN given for di-HCl salt; inhibits Rho-associated protein kinase; inhibits calcium sensitization to affect smooth muscle relaxation; structure in first source. Y-27632 : A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme.	2.08	1	0	aromatic amide
octreotide [no description available]	3.23	1	0
epothilone a Epothilones: A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).	2.04	1	0	epothilone; epoxide	antineoplastic agent; metabolite; microtubule-stabilising agent; tubulin modulator
eptifibatide [no description available]	3.23	1	0	homodetic cyclic peptide; macrocycle; organic disulfide	anticoagulant; platelet aggregation inhibitor
6-bromoindirubin-3'-oxime 6-bromoindirubin-3'-oxime: structure in first source. 6-bromoindirubin-3'-oxime : A member of the class of biindoles that is indirubin substituted at position 6 by a bromo group and in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.	2.08	1	0
purvalanol b purvalanol B: protein kinase inhibitor; structure in first source	2.08	1	0	purvalanol	protein kinase inhibitor
y-700 [no description available]	2.08	1	0
repsox RepSox: inhibits TGF-beta signaling; structure in first source appears to be incorrect	2.08	1	0	pyrazolopyridine
decitabine [no description available]	3.61	2	0	2'-deoxyribonucleoside
teniposide [no description available]	3.23	1	0	aromatic ether; beta-D-glucoside; cyclic acetal; furonaphthodioxole; gamma-lactone; monosaccharide derivative; phenols; thiophenes	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
ketoconazole (2R,4S)-ketoconazole : A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration.	3.51	1	0	cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
purvalanol a 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine: purvalanol A is the (1R)-isomer;	2.41	1	0	purvalanol
dactinomycin Dactinomycin: A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)	4.39	3	0	actinomycin	mutagen
melphalan Melphalan: An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.. melphalan : A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.	3.23	1	0	L-phenylalanine derivative; nitrogen mustard; non-proteinogenic L-alpha-amino acid; organochlorine compound	alkylating agent; antineoplastic agent; carcinogenic agent; drug allergen; immunosuppressive agent
sitafloxacin [no description available]	2.21	1	0	fluoroquinolone antibiotic; quinolines; quinolone antibiotic
benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde: proteasome inhibitor. N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal : A tripeptide that is L-leucyl-L-leucyl-L-leucine in which the C-terminal carboxy group has been reduced to the corresponding aldehyde and the N-terminal amino group is protected as its benzyloxycarbonyl derivative.	2.02	1	0	amino aldehyde; carbamate ester; tripeptide	proteasome inhibitor
tenofovir tenofovir (anhydrous) : A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.	3.23	1	0	nucleoside analogue; phosphonic acids	antiviral drug; drug metabolite; HIV-1 reverse transcriptase inhibitor
posaconazole [no description available]	4.22	2	0	aromatic ether; conazole antifungal drug; N-arylpiperazine; organofluorine compound; oxolanes; triazole antifungal drug; triazoles	trypanocidal drug
micafungin Micafungin: A cyclic lipo-hexapeptide echinocandin antifungal agent that is used for the treatment and prevention of CANDIDIASIS.. micafungin : A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy.	4.22	2	0	antibiotic antifungal drug; echinocandin	antiinfective agent
4,4-difluoro-N-[(1S)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]-1-cyclohexanecarboxamide [no description available]	2.08	1	0	tropane alkaloid
riboflavin vitamin B2 : Any member of a group of vitamers that belong to the chemical structural class called flavins that exhibit biological activity against vitamin B2 deficiency. Symptoms associated with vitamin B2 deficiency include glossitis, seborrhea, angular stomaitis, cheilosis and photophobia. The vitamers include riboflavin and its phosphate derivatives (and includes their salt, ionised and hydrate forms).	3.23	1	0	flavin; vitamin B2	anti-inflammatory agent; antioxidant; cofactor; Escherichia coli metabolite; food colouring; fundamental metabolite; human urinary metabolite; mouse metabolite; photosensitizing agent; plant metabolite
2'-c-methylcytidine 2'-C-methylcytidine: structure in first source	2.89	3	0
sodium bicarbonate Sodium Bicarbonate: A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.	3.23	1	0	one-carbon compound; organic sodium salt	antacid; food anticaking agent
arsenic trioxide Tetraarsenic Oxide: A form of As2O3 that exists as As4O6 in the solid state. It dissociates to As2O3 upon heating to the vapor phase above 800 degrees Celsius.	3.23	1	0	arsenic oxide	antineoplastic agent; insecticide
jp-1302 [no description available]	2.89	3	0
tolfenamic acid tolfenamic acid: structure. tolfenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 3-chloro-2-methylphenyl group. Tolfenamic acid is used specifically for relieving the pain of migraine. It also shows anticancer activity.	3.41	1	0	aminobenzoic acid; organochlorine compound; secondary amino compound	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; EC 2.7.1.33 (pantothenate kinase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one [no description available]	2.89	3	0	benzodiazepine
sr 90107 fondaparinux sodium : An organic sodium salt, being the decasodium salt of fondaparinux.	3.23	1	0
meglumine iodipamide [no description available]	3.23	1	0	organoammonium salt	radioopaque medium
tenatoprazole Tenatoprazole: structure in first source	2.89	3	0	imidazopyridine
thyrotropin-releasing hormone PR 546: no other info available 9/89. protirelin : A tripeptide composed of L-pyroglutamyl, L-histidyl and L-prolinamide residues joined in sequence.	3.23	1	0	peptide hormone; tripeptide	human metabolite
arginine vasopressin Arginine Vasopressin: The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.. argipressin : The predominant form of mammalian vasopressin (antidiuretic hormone). It is a nonapeptide containing an arginine at residue 8 and two disulfide-linked cysteines at residues of 1 and 6.	3.23	1	0	vasopressin	cardiovascular drug; hematologic agent; mitogen
5-[(2-fluoroanilino)methyl]-8-quinolinol [no description available]	2.89	3	0	hydroxyquinoline
benidipine hydrochloride [no description available]	2.59	2	0
benidipine benidipine: RN refers to (R,R)-(+-)-isomer	2.21	1	0
fludarabine [no description available]	4.76	5	0	purine nucleoside
propylthiouracil Propylthiouracil: A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534). 6-propyl-2-thiouracil : A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.	3.23	1	0	pyrimidinethione	antidote to paracetamol poisoning; antimetabolite; antioxidant; antithyroid drug; carcinogenic agent; EC 1.14.13.39 (nitric oxide synthase) inhibitor; hormone antagonist
2-(1,3-benzoxazol-2-ylamino)-5-spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclopentane]one [no description available]	2.89	3	0	quinazolines
sesquiterpenes [no description available]	2.52	2	0
chlorprothixene (E)-chlorprothixene : A chlorprothixene in which the double bond adopts an (E)-configuration.	2.89	3	0	chlorprothixene
chlorprothixene Chlorprothixene: A thioxanthine with effects similar to the phenothiazine antipsychotics.. (Z)-chlorprothixene : A chlorprothixene in which the double bond adopts a (Z)-configuration.	3.51	1	0	chlorprothixene
etomidate Etomidate: Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.. etomidate : The ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity.	3.23	1	0	ethyl ester; imidazoles	intravenous anaesthetic; sedative
mercaptopurine Mercaptopurine: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.. purine-6-thiol : A thiol that is the tautomer of mercaptopurine.. mercaptopurine : A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.	3.61	2	0	aryl thiol; purines; thiocarbonyl compound	anticoronaviral agent; antimetabolite; antineoplastic agent
jrf 12 N2,N4-dibenzylquinazoline-2,4-diamine: a selective, potent, reversible, and ATP-competitive p97 inhibitor	2.89	3	0
rg108 RG108: DNA methyltransferase inhibitor; structure in first source	2.08	1	0	indolyl carboxylic acid
pyrantel Pyrantel: A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It is a drug of second-choice after benzimidazoles for treatment of ascariasis, hookworm, and pinworm infections, being effective after a single dose. (From Smith and Reynard, Textbook of Pharmacology, 1992, p920). pyrantel : A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'.	3.23	1	0	1,4,5,6-tetrahydropyrimidines; carboxamidine; thiophenes	antinematodal drug
5-amino-3-(4-methoxyphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester [no description available]	2.89	3	0	methoxybenzenes; substituted aniline
stf 083010 [no description available]	2.08	1	0
4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol [no description available]	2.41	1	0	substituted aniline
3-hydroxypyridine, sodium salt [no description available]	2.89	3	0
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-naphthalenecarboxamide [no description available]	3.07	4	0	naphthalenecarboxamide
5-[(2-bromoanilino)methyl]-8-quinolinol [no description available]	2.89	3	0	hydroxyquinoline
3-amino-n-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide 3-amino-N-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide: structure in first source	2.89	3	0
N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)aniline [no description available]	2.89	3	0	aromatic amine
thiothixene [no description available]	3.23	1	0	N-methylpiperazine	anticoronaviral agent
eszopiclone Eszopiclone: A pyridine, pyrazine, and piperazine derivative that is used as a HYPNOTIC AND SEDATIVE in the treatment of INSOMNIA.. eszopiclone : The (5S)- (active) enantiomer of zopiclone. Unlike almost all other hypnotic sedatives, which are approved only for the relief of short-term (6-8 weeks) insomnia, eszopiclone is approved by the U.S. Food and Drug Administration for long-term use.	3.23	1	0	zopiclone	central nervous system depressant; sedative
curcumin Curcumin: A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.. curcumin : A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.	3.76	2	0	aromatic ether; beta-diketone; diarylheptanoid; enone; polyphenol	anti-inflammatory agent; antifungal agent; antineoplastic agent; biological pigment; contraceptive drug; dye; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor; EC 1.8.1.9 (thioredoxin reductase) inhibitor; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; flavouring agent; food colouring; geroprotector; hepatoprotective agent; immunomodulator; iron chelator; ligand; lipoxygenase inhibitor; metabolite; neuroprotective agent; nutraceutical; radical scavenger
cct018159 CCT018159: structure in first source. CCT-018159 : A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively.	2.08	1	0	benzodioxine; pyrazoles; resorcinols	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor
1-[4-(4-bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide [no description available]	2.89	3	0	piperidinecarboxamide
secinh3 SecinH3: a small molecule antagonist of cytohesins; structure in first source	2.08	1	0	triazoles
jk184 JK184: structure in first source	2.08	1	0
5-[[2-(trifluoromethyl)anilino]methyl]-8-quinolinol [no description available]	2.89	3	0	hydroxyquinoline
N-[3-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide [no description available]	2.89	3	0	acetamides; anilide
benztropine Benztropine: A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine.. benzatropine : Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.	3.23	1	0	diarylmethane
5-bromo-N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-thiophenecarboxamide [no description available]	2.89	3	0	aromatic amide; thiophenes
6-amino-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-sulfanylidene-4-pyrimidinone [no description available]	2.89	3	0	dimethoxybenzene
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide [no description available]	2.89	3	0	aromatic amide
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamide [no description available]	2.89	3	0	aromatic ether
methimazole Methimazole: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.. methimazole : A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen.	3.23	1	0	1,3-dihydroimidazole-2-thiones	antithyroid drug
3-chloro-1-(2,5-dimethoxyphenyl)-4-(1-piperidinyl)pyrrole-2,5-dione [no description available]	2.89	3	0	maleimides
Src Inhibitor-1 Src Inhibitor-1 : A member of the class of quinazolines that is quinazoline which is substituted at position 4 by a p-phenoxyanilino group and at positions 6 and 7 by methoxy groups. It is a potent, competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor. Src Inhibitor-1 is one of the 'gold standards' for Src kinase inhibition that has been shown to use PP1 or PP2 in parallel with Src-I1 to inhbit Src family kinases.	2.89	3	0	aromatic ether; polyether; quinazolines; secondary amino compound	EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
1-[2-(3,4-dimethoxyphenyl)ethyl]-6-propyl-2-sulfanylidene-7,8-dihydro-5H-pyrimido[4,5-d]pyrimidin-4-one [no description available]	2.89	3	0	dimethoxybenzene
sulindac Sulindac: A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.. sulindac : A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.	3.23	1	0	monocarboxylic acid; organofluorine compound; sulfoxide	analgesic; antineoplastic agent; antipyretic; apoptosis inducer; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug; tocolytic agent
terbinafine [no description available]	3.23	1	0	acetylenic compound; allylamine antifungal drug; enyne; naphthalenes; tertiary amine	EC 1.14.13.132 (squalene monooxygenase) inhibitor; P450 inhibitor; sterol biosynthesis inhibitor
2-phenyl-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamide [no description available]	2.89	3	0	quinolines
xl147 [no description available]	2.15	1	0	aromatic amine; benzothiadiazole; quinoxaline derivative; sulfonamide	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
3-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine [no description available]	2.89	3	0	pyrroles
thioguanine anhydrous Thioguanine: An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.. tioguanine : A 2-aminopurine that is the 6-thiono derivative of 2-amino-1,9-dihydro-6H-purine. Incorporates into DNA and inhibits synthesis. Used in the treatment of leukaemia.	3.23	1	0	2-aminopurines	anticoronaviral agent; antimetabolite; antineoplastic agent
thioacetamide Thioacetamide: A crystalline compound used as a laboratory reagent in place of HYDROGEN SULFIDE. It is a potent hepatocarcinogen.. thioacetamide : A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.	2.47	2	0	thiocarboxamide	hepatotoxic agent
succimer Succimer: A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.. succimer : A sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning.	3.23	1	0	dicarboxylic acid; dithiol; sulfur-containing carboxylic acid	chelator
digoxin Digoxin: A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666). digoxin : A cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.	4.2	2	0	cardenolide glycoside; steroid saponin	anti-arrhythmia drug; cardiotonic drug; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; epitope
streptozocin [no description available]	3.23	1	0
tamoxifen citrate [no description available]	2.08	1	0	citrate salt	angiogenesis inhibitor; anticoronaviral agent
tamoxifen [no description available]	3.61	2	0	stilbenoid; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; bone density conservation agent; EC 1.2.3.1 (aldehyde oxidase) inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; estrogen antagonist; estrogen receptor antagonist; estrogen receptor modulator
hc-067047 HC-067047: a TRPA1 antagonist; structure in first source	2.08	1	0
bi-78d3 [no description available]	3.07	4	0	aryl sulfide
ethionamide Ethionamide: A second-line antitubercular agent that inhibits mycolic acid synthesis.. ethionamide : A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide.	3.23	1	0	pyridines; thiocarboxamide	antilipemic drug; antitubercular agent; fatty acid synthesis inhibitor; leprostatic drug; prodrug
gsk 3787 [no description available]	2.08	1	0
kartogenin kartogenin: promotes chondrocyte differentiation; structure in first source	2.89	3	0
cancidas [no description available]	4.22	2	0
methyl-thiohydantoin-tryptophan methyl-thiohydantoin-tryptophan: structure in first source	3.61	2	0	organonitrogen compound; organooxygen compound
2-[2-chloro-6-ethoxy-4-[(3-methyl-5-oxo-1-phenyl-4-pyrazolylidene)methyl]phenoxy]acetic acid methyl ester [no description available]	2.08	1	0	monocarboxylic acid
4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1h-pyrazol-1-yl)benzenesulfonamide [no description available]	2.08	1	0	sulfonamide
fusidic acid Fusidic Acid: An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.. fusidic acid : A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum.	3.51	1	0	11alpha-hydroxy steroid; 3alpha-hydroxy steroid; alpha,beta-unsaturated monocarboxylic acid; steroid acid; steroid antibiotic; sterol ester	EC 2.7.1.33 (pantothenate kinase) inhibitor; Escherichia coli metabolite; protein synthesis inhibitor
lincomycin Lincomycin: An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.. lincomycin : A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis.	3.23	1	0	carbohydrate-containing antibiotic; L-proline derivative; monocarboxylic acid amide; pyrrolidinecarboxamide; S-glycosyl compound	antimicrobial agent; bacterial metabolite
ranitidine Ranitidine: A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.. ranitidine : A member of the class of furans used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease.	3.23	1	0	C-nitro compound; furans; organic sulfide; tertiary amino compound	anti-ulcer drug; drug allergen; environmental contaminant; H2-receptor antagonist; xenobiotic
aplaviroc aplaviroc: a spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly potent antiviral effects for HIV-1; structure in first source	3.23	1	0
hmr 3647 [no description available]	3.23	1	0
maraviroc [no description available]	3.58	2	0	tropane alkaloid
LSM-1318 [no description available]	2.08	1	0	oxa-steroid
toremifene Toremifene: A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.	3.66	2	0	aromatic ether; organochlorine compound; tertiary amine	antineoplastic agent; bone density conservation agent; estrogen antagonist; estrogen receptor modulator
u 0126 U 0126: protein kinase kinase inhibitor; structure in first source	3.92	2	0	aryl sulfide; dinitrile; enamine; substituted aniline	antineoplastic agent; antioxidant; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; osteogenesis regulator; vasoconstrictor agent
rwj 67657 RWJ 67657: inhibits p38 mitogen-activated protein kinase; structure in first source	2.08	1	0
nelarabine nelarabine: prodrug of ara-G. nelarabine : A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G).	3.23	1	0	beta-D-arabinoside; monosaccharide derivative; purine nucleoside	antineoplastic agent; DNA synthesis inhibitor; prodrug
6-methyl-2-(phenylethynyl)pyridine 6-methyl-2-(phenylethynyl)pyridine: an mGlu5 antagonist. 2-methyl-6-(phenylethynyl)pyridine : A methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.	2.08	1	0	acetylenic compound; methylpyridines	anxiolytic drug; metabotropic glutamate receptor antagonist
bms 387032 N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide: a CDK2 inhibitor with antineoplastic activity; structure in first source. N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of piperidine-4-carboxylic acid with the amino group of 5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-amine. It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases and exhibits anti-cancer properties.	2.78	3	0	1,3-oxazoles; 1,3-thiazoles; organic sulfide; piperidinecarboxamide; secondary carboxamide	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
lithium Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.	2.17	1	0	alkali metal atom
dermatan sulfate Dermatan Sulfate: A naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue. It differs from CHONDROITIN SULFATE A (see CHONDROITIN SULFATES) by containing IDURONIC ACID in place of glucuronic acid, its epimer, at carbon atom 5. (from Merck, 12th ed). alpha-L-IdopA-(1->3)-beta-D-GalpNAc4S : An oligosaccharide sulfate that is 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose in which the hydroxy group at position 3 has been converted to the corresponding alpha-L-idopyranuronoside.. dermatan sulfate : Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated beta1->4-linked L-iduronyl-(alpha1->3)-N-acetyl-D-galactosamine units.	3.23	1	0	amino disaccharide; glycosylgalactose derivative; iduronic acids; oligosaccharide sulfate
dolasetron [no description available]	3.23	1	0	indolyl carboxylic acid
orlistat Orlistat: A lactone derivative of LEUCINE that acts as a pancreatic lipase inhibitor to limit the absorption of dietary fat; it is used in the management of obesity.. orlistat : A carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug.	3.23	1	0	beta-lactone; carboxylic ester; formamides; L-leucine derivative	anti-obesity agent; bacterial metabolite; EC 2.3.1.85 (fatty acid synthase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor
quinine [no description available]	3.23	1	0	cinchona alkaloid	antimalarial; muscle relaxant; non-narcotic analgesic
sf 2370 SF 2370: indolocarbazole isolated from Actinomadura sp. SF-2370; structure given in first source. K-252a : A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a	2.15	1	0	bridged compound; gamma-lactam; methyl ester; organic heterooctacyclic compound	antimicrobial agent; bacterial metabolite; EC 2.7.11.13 (protein kinase C) inhibitor; tropomyosin-related kinase B receptor antagonist
fospropofol [no description available]	3.23	1	0	alkylbenzene
tandutinib [no description available]	2.78	3	0	aromatic ether; N-arylpiperazine; N-carbamoylpiperazine; phenylureas; piperidines; quinazolines; tertiary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
vx-745 [no description available]	3.39	6	0	aryl sulfide; dichlorobenzene; difluorobenzene; pyrimidopyridazine	anti-inflammatory drug; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
corlanor ivabradine hydrochloride : A hydrochloride obtained by combining ivabradine with one molar equivalent of hydrochloric acid. Used to treat patients with angina who have intolerance to beta blockers and/or heart failure.	2.08	1	0	hydrochloride	cardiotonic drug
rasagiline [no description available]	3.23	1	0	indanes; secondary amine; terminal acetylenic compound	EC 1.4.3.4 (monoamine oxidase) inhibitor; neuroprotective agent
dasatinib N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide: a dasatinib prodrug; structure in first source. dasatinib (anhydrous) : An aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN).	22.3	531	39	1,3-thiazoles; aminopyrimidine; monocarboxylic acid amide; N-(2-hydroxyethyl)piperazine; N-arylpiperazine; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
ha 1100 HA 1100: intracellular calcium antagonist	2.15	1	0
7-epi-hydroxystaurosporine [no description available]	2.15	1	0
zd 6474 CH 331: structure in first source	6.3	13	0	aromatic ether; organobromine compound; organofluorine compound; piperidines; quinazolines; secondary amine	antineoplastic agent; tyrosine kinase inhibitor
nitinol nitinol: RN given refers to cpd with MF of Ni-Ti; do not confuse with titanium nickelide; other nitinols (nitinol SE and nitinol 55) are Co-Ni-Ti alloys	2.21	1	0
N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide [no description available]	2.63	2	0	indoles
compound 968 compound 968: a glutaminase inhibitor. 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]phenanthridin-4(1H)-one : A partially hydrogenated benzophenanthridine carrying an oxo group at C-4, geminal methyl groups at C-2 and a 3-bromo-4-(dimethylamino)phenyl group at C-5.	2.08	1	0	benzophenanthridine	EC 3.5.1.2 (glutaminase) inhibitor
nih-12848 NIH-12848: inhibits phosphatidylinositol 5-phosphate 4-kinase gamma; structure in first source	2.89	3	0
2,4-dioxo-3-pentyl-N-[3-(1-piperidinyl)propyl]-1H-quinazoline-7-carboxamide [no description available]	2.89	3	0	quinazolines
[1-(3-methylphenyl)-5-benzimidazolyl]-(1-piperidinyl)methanone [no description available]	2.89	3	0	benzimidazoles
2-[[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile [no description available]	2.89	3	0	imidazopyridine
3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one [no description available]	2.89	3	0	aromatic ketone
ovalbumin Ovalbumin: An albumin obtained from the white of eggs. It is a member of the serpin superfamily.	2.5	2	0
sb-224289 SB 224289 : A member of the class of benzamides obtained by formal condensation of the carboxy group of 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid with the secondary amino group of 1'-methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidine]. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo.	2.08	1	0	1,2,4-oxadiazole; azaspiro compound; benzamides; organic heterotetracyclic compound	serotonergic antagonist
4-[[7-[(4-fluorophenyl)methyl]-1,3-dimethyl-2,6-dioxo-8-purinyl]methyl]-1-piperazinecarboxylic acid ethyl ester [no description available]	2.89	3	0	oxopurine
gw 7647 GW 7647: a PPAR-alpha agonist; structure in first source. GW 7647 : A monocarboxylic acid that is 2-(phenylsulfanyl)isobutyric acid in which the phenyl group is substituted at the para- position by a 3-aza-7-cyclohexylhept-1-yl group in which the nitrogen is acylated by a (cyclohexylamino)carbonyl group.	2.08	1	0	aryl sulfide; monocarboxylic acid; ureas	PPARalpha agonist
N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester [no description available]	2.89	3	0	organonitrogen compound; organosulfur compound
6-bromo-2-(4-methylphenyl)-N-[(1-methyl-4-pyrazolyl)methyl]-4-quinolinecarboxamide [no description available]	2.89	3	0	quinolines
8-(Trifluoromethyl)-9H-purin-6-amine [no description available]	2.15	1	0	6-aminopurines	anticoronaviral agent
l 663536 MK-886: orally active leukotriene biosynthesis inhibitor. 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid : A member of the class of indoles that is 1H-indole substituted by a isopropyl group at position 5, a tert-butylsulfanediyl group at position 3, a 4-chlorobenzyl group at position 1 and a 2-carboxy-2-methylpropyl group at position 2. It acts as an inhibitor of arachidonate 5-lipoxygenase.	2.08	1	0	aryl sulfide; indoles; monocarboxylic acid; monochlorobenzenes	antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; leukotriene antagonist
LSM-1924 [no description available]	2.89	3	0	organic heterotricyclic compound; organooxygen compound
1-[6-(4-chlorophenyl)-5-imidazo[2,1-b]thiazolyl]-N-[(3,4-dichlorophenyl)methoxy]methanimine [no description available]	2.08	1	0	imidazoles
zinc protoporphyrin ix [no description available]	2.07	1	0
sb 225002 [no description available]	2.31	1	0	nitrophenol
N4-ethyl-N6,1,2-trimethyl-N4-phenylpyrimidin-1-ium-4,6-diamine [no description available]	2.08	1	0	aromatic amine; tertiary amino compound
ferrostatin-1 ferrostatin-1: inhibits ferroptosis, an iron-dependent form of nonapoptotic cell death; structure in first source. ferrostatin-1 : An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.	2.89	3	0	ethyl ester; primary arylamine; substituted aniline	antifungal agent; antioxidant; ferroptosis inhibitor; neuroprotective agent; radiation protective agent; radical scavenger
2-[[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxo-5-isoquinolinyl]oxy]propanoic acid ethyl ester [no description available]	2.08	1	0	isoquinolines
sch 79797 [no description available]	2.08	1	0	quinazolines
6-(2-methyl-1-piperidinyl)-5-nitro-4-pyrimidinamine [no description available]	2.89	3	0	C-nitro compound
sitagliptin sitagliptin : A triazolopyrazine that exhibits hypoglycemic activity.	3.61	2	0	triazolopyrazine; trifluorobenzene	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; environmental contaminant; hypoglycemic agent; serine proteinase inhibitor; xenobiotic
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide: a TGF-beta type I receptor kinase activity inhibitor	2.08	1	0	benzamides; benzodioxoles; imidazoles; pyridines	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
rabeprazole(1-) [no description available]	2.63	2	0	organic nitrogen anion
tolcapone Tolcapone: A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated.. tolcapone : Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase.	3.23	1	0	2-nitrophenols; benzophenones; catechols	antiparkinson drug; EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one [no description available]	2.08	1	0	monobactam
alsterpaullone alsterpaullone: structure in first source. alsterpaullone : An organic heterotetracyclic compound that is 1,3-dihydro-2H-1-benzazepin-2-one which shares its 4-5 bond with the 3-2 bond of 5-nitro-1H-indole.	3.92	2	0	C-nitro compound; caprolactams; organic heterotetracyclic compound	anti-HIV-1 agent; antineoplastic agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor; EC 2.7.11.26 (tau-protein kinase) inhibitor
imd 0354 N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide: a cardioprotective agent that inhibits IkappaB kinase beta (IKKbeta); structure in first source	2.52	2	0	benzamides
ex 527 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide: structure in first source. 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide : A member of the class of carbazoles that is 2,3,4,9-tetrahydro-1H-carbazole which is substituted at position 1 by an aminocarbohyl group and at position 6 by a chlorine.	2.08	1	0	carbazoles; monocarboxylic acid amide; organochlorine compound
ncgc00099374 [no description available]	2.89	3	0
2-nitro-4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide [no description available]	2.89	3	0	benzamides
sq 109 N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine: has antitubercular activity	3.51	1	0
sphingosine sphing-4-enine : A sphingenine in which the C=C double bond is located at the 4-position.. sphingenine : A 2-aminooctadecene-1,3-diol having (2S,3R)-configuration.. sphingoid : Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds.. 2-aminooctadec-4-ene-1,3-diol : A 2-aminooctadecene-1,3-diol having its double bond at position 4.	2.06	1	0	sphing-4-enine	human metabolite; mouse metabolite
quercetin [no description available]	2.49	2	0	7-hydroxyflavonol; pentahydroxyflavone	antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger
bilirubin [no description available]	4.57	5	1	biladienes; dicarboxylic acid	antioxidant; human metabolite; mouse metabolite
apigenin Chamomile: Common name for several daisy-like plants (MATRICARIA; TRIPLEUROSPERMUM; ANTHEMIS; CHAMAEMELUM) native to Europe and Western Asia, now naturalized in the United States and Australia.	3.51	1	0	trihydroxyflavone	antineoplastic agent; metabolite
luteolin [no description available]	2.89	3	0	3'-hydroxyflavonoid; tetrahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; c-Jun N-terminal kinase inhibitor; EC 2.3.1.85 (fatty acid synthase) inhibitor; immunomodulator; nephroprotective agent; plant metabolite; radical scavenger; vascular endothelial growth factor receptor antagonist
calcitriol dihydroxy-vitamin D3: as a major in vitro metabolite of 1alpha,25-dihydroxyvitamin D3, produced in primary cultures of neonatal human keratinocytes	3.98	3	0	D3 vitamins; hydroxycalciol; triol	antineoplastic agent; antipsoriatic; bone density conservation agent; calcium channel agonist; calcium channel modulator; hormone; human metabolite; immunomodulator; metabolite; mouse metabolite; nutraceutical
cyclosporine [no description available]	2.21	1	0
vitamin d 2 Ergocalciferols: Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.. vitamin D2 : A vitamin D supplement and has been isolated from alfalfa.	3.23	1	0	hydroxy seco-steroid; seco-ergostane; vitamin D	bone density conservation agent; nutraceutical; plant metabolite; rodenticide
cholecalciferol Cholecalciferol: Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.. calciol : A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.	2.17	1	0	D3 vitamins; hydroxy seco-steroid; seco-cholestane; secondary alcohol; steroid hormone	geroprotector; human metabolite
kaempferol [no description available]	2.89	3	0	7-hydroxyflavonol; flavonols; tetrahydroxyflavone	antibacterial agent; geroprotector; human blood serum metabolite; human urinary metabolite; human xenobiotic metabolite; plant metabolite
genistein [no description available]	4.55	6	0	7-hydroxyisoflavones	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; human urinary metabolite; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
amphotericin b Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.	4.22	2	0	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite
pulmicort Budesonide: A glucocorticoid used in the management of ASTHMA, the treatment of various skin disorders, and allergic RHINITIS.. budesonide : A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.	3.23	1	0	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; cyclic acetal; glucocorticoid; primary alpha-hydroxy ketone	anti-inflammatory drug; bronchodilator agent; drug allergen
oxymetholone Oxymetholone: A synthetic hormone with anabolic and androgenic properties. It is used mainly in the treatment of anemias. According to the Fourth Annual Report on Carcinogens (NTP 85-002), this compound may reasonably be anticipated to be a carcinogen. (From Merck Index, 11th ed). oxymetholone : A 3-oxo-5alpha- steroid that is 4,5alpha-dihydrotestosterone which is substituted by a hydroxymethylidene group at position 2 and by a methyl group at the 17alpha position. A synthetic androgen, it was mainly used for the treatment of anaemias until being replaced by treatments with fewer side effects.	3.23	1	0
pyrvinium pyrvinium: RN given refers to parent cpd; synonyms vanquin & vankin refer to pamoate[2:1]; structure in Merck Index, 9th ed, #7810. pyrvinium : A quinolinium ion that is 1-methylquinolinium substituted by dimethylamino group at position 6 and a (E)-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl at position 2. It is a anthelminthic drug active against pinworms. The salts of pyrvinium can also be used as anticancer agents.	3.41	1	0	quinolinium ion	anthelminthic drug; antineoplastic agent
eprosartan eprosartan: angiotensin II receptor antagonist. eprosartan : A member of the class of imidazoles and thiophenes that is an angiotensin II receptor antagonist used for the treatment of high blood pressure.	3.23	1	0	dicarboxylic acid; imidazoles; thiophenes	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
montelukast montelukast: a leukotriene D4 receptor antagonist	3.23	1	0	aliphatic sulfide; monocarboxylic acid; quinolines	anti-arrhythmia drug; anti-asthmatic drug; leukotriene antagonist
mivacurium Mivacurium: An isoquinoline derivative that is used as a short-acting non-depolarizing agent.	3.23	1	0	isoquinolines
hemabate carboprost tromethamine : The tromethamine salt of carboprost. It is used as an abortifacient agent that is effective in both the first and second trimesters of pregnancy.	3.23	1	0
mycophenolate mofetil mycophenolate mofetil : A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.	4.19	4	0	carboxylic ester; ether; gamma-lactone; phenols; tertiary amino compound	anticoronaviral agent; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; immunosuppressive agent; prodrug
entacapone entacapone: structure given in first source. entacapone : A monocarboxylic acid amide that is N,N-diethylprop-2-enamide in which the hydrogen at position 2 is substituted by a cyano group and the hydrogen at the 3E position is substituted by a 3,4-dihydroxy-5-nitrophenyl group.	3.23	1	0	2-nitrophenols; catechols; monocarboxylic acid amide; nitrile	antidyskinesia agent; antiparkinson drug; central nervous system drug; EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
paricalcitol [no description available]	3.23	1	0	hydroxy seco-steroid; seco-cholestane	antiparathyroid drug
bruceantin [no description available]	2.89	3	0	triterpenoid
chrysin chrysin : A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.	2.89	3	0	7-hydroxyflavonol; dihydroxyflavone	anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite
diosmetin [no description available]	3.51	1	0	3'-hydroxyflavonoid; monomethoxyflavone; trihydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; bone density conservation agent; cardioprotective agent; plant metabolite; tropomyosin-related kinase B receptor agonist; vasodilator agent
daidzein [no description available]	2.89	3	0	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; phytoestrogen; plant metabolite
rottlerin rottlerin: an angiogenesis inhibitor; an inhibitor of protein kinase Cdelta (PKCdelta) and calmodulin kinase III; RN refers to (E)-isomer; do not confuse this chalcone with an anthraquinone that is also called rottlerin (RN 481-72-1);. rottlerin : A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis.	2.41	1	0	aromatic ketone; benzenetriol; chromenol; enone; methyl ketone	anti-allergic agent; antihypertensive agent; antineoplastic agent; apoptosis inducer; K-ATP channel agonist; metabolite
sdz psc 833 valspodar: nonimmunosuppressive cyclosporin analog which is a potent multidrug resistance modifier; 7-10 fold more potent than cyclosporin A; a potent P glycoprotein inhibitor; MW 1215	2.47	2	0	homodetic cyclic peptide
l 660,711 [no description available]	3.51	1	0	quinolines
tectochrysin tectochrysin: structure in first source. tectochrysin : A monohydroxyflavone that is flavone substituted by a hydroxy group at position 4 and a methoxy group at position 7 respectively.	3.51	1	0	monohydroxyflavone; monomethoxyflavone	antidiarrhoeal drug; antineoplastic agent; plant metabolite
7432 s Ceftibuten: A cephalosporin antibacterial agent that is used in the treatment of infections, including urinary-tract and respiratory-tract infections.. ceftibuten : A third-generation cephalosporin antibiotic with a [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino substituent at the 7 position of the cephem skeleton. An orally-administered agent, ceftibuten is used as the dihydrate to treat urinary-tract and respiratory-tract infections.	3.23	1	0	cephalosporin; dicarboxylic acid	antibacterial drug
isotretinoin Isotretinoin: A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. The drug has teratogenic and other adverse effects.. isotretinoin : A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.	3.23	1	0	retinoic acid	antineoplastic agent; keratolytic drug; teratogenic agent
epoprostenol [no description available]	3.23	1	0	prostaglandins I	mouse metabolite
indocyanine green [no description available]	3.23	1	0	1,1-diunsubstituted alkanesulfonate; benzoindole; cyanine dye
neticonazole neticonazole: RN refers to (E)-isomer. neticonazole : An enamine that is ethene which is substituted at positions 1, 1, and 2 by o-pentoxyphenyl, 1H-imidazol-1-yl, and methylthio groups, respectively (the E isomer). An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan (generally as the corresponding hydrochloride salt) as an antifungal drug for the treatment of superficial skin infections.	2.89	3	0	aromatic ether; benzenes; conazole antifungal drug; enamine; imidazole antifungal drug; imidazoles; methyl sulfide	antifungal drug; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
triprolidine Triprolidine: Histamine H1 antagonist used in allergic rhinitis; ASTHMA; and URTICARIA. It is a component of COUGH and COLD medicines. It may cause drowsiness.. triprolidine : An N-alkylpyrrolidine that is acrivastine in which the pyridine ring is lacking the propenoic acid substituent. It is a sedating antihistamine that is used (generally as the monohydrochloride monohydrate) for the relief of the symptoms of uticaria, rhinitis, and various pruritic skin disorders.	3.23	1	0	N-alkylpyrrolidine; olefinic compound; pyridines	H1-receptor antagonist
pitavastatin pitavastatin : A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.	3.23	1	0	cyclopropanes; dihydroxy monocarboxylic acid; monofluorobenzenes; quinolines; statin (synthetic)	antioxidant
ethamolin monoethanolamine oleate: used for treatment of pyogenic granuloma	3.23	1	0	long-chain fatty acid
alatrofloxacin mesylate [no description available]	3.23	1	0
N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine synaptamide: structurally similar to the endocannabinoid N-arachidonoylethanolamine (anandamide). N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine : An N-acylethanolamine 22:6 that is the ethanolamide of (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid.	2.89	3	0	endocannabinoid; N-acylethanolamine 22:6
n-oleoylethanolamine N-oleoylethanolamine: ceramidase inhibitor. oleoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide.	2.89	3	0	endocannabinoid; N-(long-chain-acyl)ethanolamine; N-acylethanolamine 18:1	EC 3.5.1.23 (ceramidase) inhibitor; geroprotector; PPARalpha agonist
1-monooleoyl-rac-glycerol Peceol: lipid excipient containing readily dispersible mixture of mono- & diglycerides of oleic acid. 1-oleoylglycerol : A 1-monoglyceride where the acyl group is oleoyl.. monooleoylglycerol : A monoglyceride in which the acyl group is oleoyl with the position of acylation unspecified.	2.25	1	0	1-acylglycerol 18:1; monooleoylglycerol	plant metabolite
sphingosine 1-phosphate sphingosine 1-phosphate: RN given refers to (R-(R,S-(E)))-isomer; RN for cpd without isomeric designation not available 8/89. sphingosine 1-phosphate : A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1	2.06	1	0	sphingoid 1-phosphate	mouse metabolite; signalling molecule; sphingosine-1-phosphate receptor agonist; T-cell proliferation inhibitor; vasodilator agent
codeine [no description available]	3.23	1	0	morphinane alkaloid; organic heteropentacyclic compound	antitussive; drug allergen; environmental contaminant; opioid analgesic; opioid receptor agonist; prodrug; xenobiotic
cyclosporine ramihyphin A: one of the metabolites produced by Fusarium sp. S-435; RN given refers to cpd with unknown MF	4.22	2	0	homodetic cyclic peptide	anti-asthmatic drug; anticoronaviral agent; antifungal agent; antirheumatic drug; carcinogenic agent; dermatologic drug; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; geroprotector; immunosuppressive agent; metabolite
acitretin Acitretin: An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate.. acitretin : A retinoid that consists of 3,7-dimethylnona-2,4,6,8-tetraenoic acid having a 4-methoxy-2,3,6-trimethylphenyl group attached at position 9.	3.23	1	0	acitretin; alpha,beta-unsaturated monocarboxylic acid; retinoid	keratolytic drug
estropipate estropipate: used therapeutically in menopausal patients	3.23	1	0	piperazinium salt; steroid sulfate
hydromorphone Hydromorphone: An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.. hydromorphone : A morphinane alkaloid that is a hydrogenated ketone derivative of morphine. A semi-synthetic drug, it is a centrally acting pain medication of the opioid class.	3.23	1	0	morphinane alkaloid; organic heteropentacyclic compound	mu-opioid receptor agonist; opioid analgesic
levetiracetam Levetiracetam: A pyrrolidinone and acetamide derivative that is used primarily for the treatment of SEIZURES and some movement disorders, and as a nootropic agent.. levetiracetam : A pyrrolidinone and carboxamide that is N-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the S enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine.	3.23	1	0	pyrrolidin-2-ones	anticonvulsant; environmental contaminant; xenobiotic
ly 163892 loracarbef: 1-carbacephem antibiotic; has a broad spectrum of antimicrobial activity; structure given in first source; carbacephems differ from cephalosporins in the substitution of a sulfur atom in the dihydrothiazine ring with a methylene group to form a tetrahydropyridine ring. loracarbef : A synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria.	3.23	1	0	carbacephem; zwitterion	antibacterial drug; antimicrobial agent
nabilone nabilone: cannabinol deriv; RN given refers to cpd without isomeric designation; structure	3.23	1	0
naloxone Naloxone: A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.. naloxone : A synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose.	3.23	1	0	morphinane alkaloid; organic heteropentacyclic compound; tertiary alcohol	antidote to opioid poisoning; central nervous system depressant; mu-opioid receptor antagonist
oxycodone Oxycodone: A semisynthetic derivative of CODEINE.. oxycodone : A semisynthetic opioid of formula C18H21NO4 that is derived from thebaine. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain.	3.23	1	0	organic heteropentacyclic compound; semisynthetic derivative	antitussive; mu-opioid receptor agonist; opioid analgesic
oxymorphone Oxymorphone: An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)	3.23	1	0	morphinane alkaloid
vitamin k 1 Vitamin K 1: A family of phylloquinones that contains a ring of 2-methyl-1,4-naphthoquinone and an isoprenoid side chain. Members of this group of vitamin K 1 have only one double bond on the proximal isoprene unit. Rich sources of vitamin K 1 include green plants, algae, and photosynthetic bacteria. Vitamin K1 has antihemorrhagic and prothrombogenic activity.. phylloquinone : A member of the class of phylloquinones that consists of 1,4-naphthoquinone having methyl and phytyl groups at positions 2 and 3 respectively. The parent of the class of phylloquinones.	3.23	1	0	phylloquinones; vitamin K	cofactor; human metabolite; plant metabolite
sirolimus Sirolimus: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.. sirolimus : A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.	6.23	13	0	antibiotic antifungal drug; cyclic acetal; cyclic ketone; ether; macrolide lactam; organic heterotricyclic compound; secondary alcohol	antibacterial drug; anticoronaviral agent; antineoplastic agent; bacterial metabolite; geroprotector; immunosuppressive agent; mTOR inhibitor
topiramate Topiramate: A sulfamate-substituted fructose analog that was originally identified as a hypoglycemic agent. It is used for the treatment of EPILEPSY and MIGRAINE DISORDERS, and may also promote weight loss.. topiramate : A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.	3.23	1	0	cyclic ketal; ketohexose derivative; sulfamate ester	anticonvulsant; sodium channel blocker
trospium chloride trospium chloride : An organic chloride salt of trospium. It is an antispasmodic drug used for the treatment of overactive bladder.	3.23	1	0
alpha-zearalenol [no description available]	2.89	3	0	macrolide
alvocidib alvocidib: structure given in first source. alvocidib : A synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the (-)-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation.	4.19	4	0	dihydroxyflavone; hydroxypiperidine; monochlorobenzenes; tertiary amino compound	antineoplastic agent; antirheumatic drug; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
fenretinide Fenretinide: A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.. 4-hydroxyphenyl retinamide : A retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.	3.65	2	0	monocarboxylic acid amide; retinoid	antineoplastic agent; antioxidant
topiroxostat FYX-051: xanthine oxidoreductase inhibitor	3.51	1	0
geldanamycin [no description available]	2.21	1	0	1,4-benzoquinones; ansamycin; carbamate ester; organic heterobicyclic compound	antimicrobial agent; antineoplastic agent; antiviral agent; cysteine protease inhibitor; Hsp90 inhibitor
ic 261 IC 261: a caseine kinase-1 inhibitor; structure in first source	3.25	1	0
morphine Meconium: The thick green-to-black mucilaginous material found in the intestines of a full-term fetus. It consists of secretions of the INTESTINAL GLANDS; BILE PIGMENTS; FATTY ACIDS; AMNIOTIC FLUID; and intrauterine debris. It constitutes the first stools passed by a newborn.	3.23	1	0	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic
su 9516 [no description available]	2.89	3	0
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine [no description available]	2.89	3	0	triazolopyrimidines
ter 199 [no description available]	2.08	1	0
arachidonylcyclopropylamide arachidonylcyclopropylamide: a potent and selective agonist of neuronal cannabinoid receptor; structure in first source	2.08	1	0
benzphetamine Benzphetamine: A sympathomimetic agent with properties similar to DEXTROAMPHETAMINE. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222). benzphetamine : Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity.	3.23	1	0	amphetamines; tertiary amine	adrenergic uptake inhibitor; appetite depressant; dopamine uptake inhibitor; sympathomimetic agent
deamino arginine vasopressin Deamino Arginine Vasopressin: A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR.	3.23	1	0	heterodetic cyclic peptide	diagnostic agent; renal agent; vasopressin receptor agonist
dexmedetomidine [no description available]	3.23	1	0	medetomidine	alpha-adrenergic agonist; analgesic; non-narcotic analgesic; sedative
sb 277011 SB 277011: structure in first source	2.89	3	0
fluticasone Fluticasone: A STEROID with GLUCOCORTICOID RECEPTOR activity that is used to manage the symptoms of ASTHMA; ALLERGIC RHINITIS, and ATOPIC DERMATITIS.. fluticasone : A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.	2.13	1	0	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 3-oxo-Delta(4) steroid; corticosteroid; fluorinated steroid; thioester	anti-allergic agent; anti-asthmatic drug
pd 180970 PD 180970: inhibits p210(Bcr-Abl) tyrosine kinase; structure in first source	3.13	1	0
goserelin Goserelin: A synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE. Goserelin is used in treatments of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast cancer.	3.23	1	0	organic molecular entity
ly 320135 LY 320135: cannabinoid receptor antagonist; structure in first source	2.08	1	0	benzofurans
nalbuphine Nalbuphine: A narcotic used as a pain medication. It appears to be an agonist at KAPPA RECEPTORS and an antagonist or partial agonist at MU RECEPTORS.	3.23	1	0	organic heteropentacyclic compound	mu-opioid receptor antagonist; opioid analgesic
nateglinide Nateglinide: A phenylalanine and cyclohexane derivative that acts as a hypoglycemic agent by stimulating the release of insulin from the pancreas. It is used in the treatment of TYPE 2 DIABETES.. nateglinide : An N-acyl-D-phenylalanine resulting from the formal condensation of the amino group of D-phenylalanine with the carboxy group of trans-4-isopropylcyclohexanecarboxylic acid. An orally-administered, rapidly-absorbed, short-acting insulinotropic agent, it is used for the treatment of type 2 diabetes mellitus.	3.23	1	0	phenylalanine derivative
pd 166285 [no description available]	2.08	1	0
sb 223412 SB 223412: SB-223412 is the (S)-(-)-isomer; RN given for (S)-isomer; structure in first source	2.89	3	0
sr 59230a [no description available]	2.89	3	0	tetralins
vinorelbine [no description available]	3.23	1	0	acetate ester; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; ring assembly; vinca alkaloid	antineoplastic agent; photosensitizing agent
3-[6-[4-(trifluoromethoxy)anilino]-4-pyrimidinyl]benzamide [no description available]	3.31	5	0	pyrimidines
silodosin silodosin: an alpha(1a)-adrenoceptor-selective antagonist; structure given in first source	3.23	1	0	indolecarboxamide
kn 62 KN 62: inhibitor of Ca/calmodulin-dependent protein kinase II	3.07	4	0	piperazines
su 6656 SU 6656: a c-Src kinase inhibitor; used to probe growth signaling; structure in first source. SU6656 : A member of the class of oxindoles that is 3-methyleneoxindole in which the hydrogeh at position 5 has been replaced by a dimethylaminosulfonyl group and in which one of the hydrogens of the methylene group has been replaced by a 4,5,6,7-tetrahydro-indol-2-yl group. It is a specific inhibitor of Src family kinase.	3.56	2	0
MeJA [no description available]	2.89	3	0	Jasmonate derivatives
fluvoxamine Fluvoxamine: A selective serotonin reuptake inhibitor that is used in the treatment of DEPRESSION and a variety of ANXIETY DISORDERS.. fluvoxamine : An oxime O-ether that is benzene substituted by a (1E)-N-(2-aminoethoxy)-5-methoxypentanimidoyl group at position 1 and a trifluoromethyl group at position 4. It is a selective serotonin reuptake inhibitor that is used for the treatment of obsessive-compulsive disorder.	3.23	1	0	(trifluoromethyl)benzenes; 5-methoxyvalerophenone O-(2-aminoethyl)oxime	antidepressant; anxiolytic drug; serotonin uptake inhibitor
1h-pyrrole-2,5-dione, 3-(1-methyl-1h-indol-3-yl)-4-(1-methyl-6-nitro-1h-indol-3-yl)- 1H-pyrrole-2,5-dione, 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)-: structure in first source	2.89	3	0
pd 161570 PD 161570: structure in first source	2.89	3	0
bosutinib 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile: a Src kinase inhibitor; structure in first source	14.61	77	3	aminoquinoline; aromatic ether; dichlorobenzene; N-methylpiperazine; nitrile; tertiary amino compound	antineoplastic agent; tyrosine kinase inhibitor
semaxinib semaxanib : An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is replaced by a 3,5-dimethylpyrrol-2-yl group.	2.08	1	0	olefinic compound; oxindoles; pyrroles	angiogenesis modulating agent; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist
orantinib orantinib: an antiangiogenic agent. orantinib : An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1.	2.15	1	0
su 11248 [no description available]	13.33	50	3	monocarboxylic acid amide; pyrroles	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; immunomodulator; neuroprotective agent; vascular endothelial growth factor receptor antagonist
palbociclib [no description available]	5.32	8	0	aminopyridine; aromatic ketone; cyclopentanes; piperidines; pyridopyrimidine; secondary amino compound; tertiary amino compound	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
jnj-7706621 [no description available]	3.07	4	0	sulfonamide
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid : A dihydroxy monocarboxylic acid that is N-isopropylindole which is substituted at position 3 by a p-fluorophenyl group and at position 2 by a 6-carboxy-3,5-dihydroxyhex-1-en-1-yl group. It has four possible diastereoisomers.	3.23	1	0	dihydroxy monocarboxylic acid; indoles; organofluorine compound
levorphanol Levorphanol: A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.	3.23	1	0	morphinane alkaloid
arsenic Arsenic: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)	2.08	1	0	metalloid atom; pnictogen	micronutrient
naltrexone Naltrexone: Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.. naltrexone : An organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A mu-opioid receptor antagonist, it is used to treat alcohol dependence.	3.23	1	0	cyclopropanes; morphinane-like compound; organic heteropentacyclic compound	antidote to opioid poisoning; central nervous system depressant; environmental contaminant; mu-opioid receptor antagonist; xenobiotic
dextromethorphan Dextromethorphan: Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.. dextromethorphan : A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.	3.23	1	0	6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene	antitussive; environmental contaminant; neurotoxin; NMDA receptor antagonist; oneirogen; prodrug; xenobiotic
butorphanol Butorphanol: A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.. butorphanol : Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.	3.23	1	0	morphinane alkaloid	antitussive; kappa-opioid receptor agonist; mu-opioid receptor agonist; opioid analgesic
cefixime [no description available]	3.23	1	0	cephalosporin	antibacterial drug; drug allergen
lisinopril Lisinopril: One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure.	3.23	1	0	dipeptide	EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
benazepril benazepril: structure given in first source. benazepril : A benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure.	3.23	1	0	benzazepine; dicarboxylic acid monoester; ethyl ester; lactam	EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; prodrug
ramipril Ramipril: A long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.. ramipril : A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.. quark : Quarks comprise one of two classes of the fundamental particles. Quarks possess fractional electric charges and are not observed in free state. The word "quark" first appears in James Joyce's Finnegans Wake and has been chosen by Murray Gell-Mann as a name for fundamental building blocks of particles.	3.23	1	0	azabicycloalkane; cyclopentapyrrole; dicarboxylic acid monoester; dipeptide; ethyl ester	bradykinin receptor B2 agonist; cardioprotective agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; matrix metalloproteinase inhibitor; prodrug
verteporfin (2R,2(1)S)-8-ethenyl-2(1),2(2)-bis(methoxycarbonyl)-17-(3-methoxy-3-oxopropyl)-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-13-propanoic acid : The 2(1),2(2),17-trimethyl ester of (2R,2(1)S)-2(1),2(2)-dicarboxy-8-ethenyl-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-13,17-dipropanoic acid.	3.23	1	0
indinavir sulfate Indinavir: A potent and specific HIV protease inhibitor that appears to have good oral bioavailability.	3.23	1	0	dicarboxylic acid diamide; N-(2-hydroxyethyl)piperazine; piperazinecarboxamide	HIV protease inhibitor
zimeldine Zimeldine: One of the SEROTONIN UPTAKE INHIBITORS formerly used for depression but was withdrawn worldwide in September 1983 because of the risk of GUILLAIN-BARRE SYNDROME associated with its use. (From Martindale, The Extra Pharmacopoeia, 29th ed, p385)	3.23	1	0	styrenes
3,3',4,5'-tetramethoxy-trans-stilbene (E)-3,4,3',5'-tetramethoxystilbene: from the leaves of Eugenia rigida; structure in first source	4.43	2	0
virginiamycin factor s1 virginiamycin factor S1: a component of VIRGINIAMYCIN; was EP to VIRGINIAMYCIN 1992-2001. virginiamycin S1 : A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others.	2.89	3	0	cyclodepsipeptide; macrolide antibiotic	antibacterial drug; bacterial metabolite
enalapril Enalapril: An angiotensin-converting enzyme inhibitor that is used to treat HYPERTENSION and HEART FAILURE.. enalapril : A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).	3.23	1	0	dicarboxylic acid monoester; dipeptide	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; geroprotector; prodrug
trientine hydrochloride [no description available]	3.23	1	0
n-methylscopolamine bromide scopolamine methobromide : A quaternary ammonium salt resulting from the reaction of the amino group of scopolamine with methyl bromide.	3.23	1	0
cisplatin [no description available]	2.08	1	0	diamminedichloroplatinum	antineoplastic agent; apoptosis inducer; cross-linking reagent; ferroptosis inducer; genotoxin; mutagen; nephrotoxin; photosensitizing agent
bleomycin [no description available]	3.23	1	0	bleomycin	antineoplastic agent; metabolite
enalaprilat anhydrous Enalaprilat: The active metabolite of ENALAPRIL and one of the potent, intravenously administered, ANGIOTENSIN-CONVERTING ENZYME INHIBITORS. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.. enalaprilat dihydrate : The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.. enalaprilat (anhydrous) : Enalapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid. Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor and is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is given by intravenous injection, usually as the dihydrate.	3.23	1	0	dicarboxylic acid; dipeptide	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
ximelagatran ximelagatran: prodrug (via hydroxylation) of melagatran & a direct thrombin inhibitor; liver toxicity concerns so AZD0837 being developed to replace this. ximelagatran : A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted into the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage.	3.66	2	0	amidoxime; azetidines; carboxamide; ethyl ester; hydroxylamines; secondary amino compound; secondary carboxamide; tertiary carboxamide	anticoagulant; EC 3.4.21.5 (thrombin) inhibitor; prodrug; serine protease inhibitor
cefuroxime [no description available]	3.23	1	0	3-(carbamoyloxymethyl)cephalosporin; furans; oxime O-ether	drug allergen
ceftriaxone [no description available]	3.61	2	0	1,2,4-triazines; 1,3-thiazoles; cephalosporin; oxime O-ether	antibacterial drug; drug allergen; EC 3.5.2.6 (beta-lactamase) inhibitor
cefepime Cefepime: A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.. cefepime : A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.	3.23	1	0	cephalosporin; oxime O-ether	antibacterial drug
pafuramidine pafuramidine: a prodrug of furamidine	3.23	1	0
ceftazidime [no description available]	3.23	1	0	cephalosporin; oxime O-ether	antibacterial drug; drug allergen; EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
trandolapril trandolapril : A heterobicylic compound that is (2S,3aR,7aS)-1-[(2S)-2-aminopropanoyl]octahydro-1H-indole-2-carboxylic acid in which the hydrogen of the amino group is substituted by a (2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl group. It is a angiotensin-converting enzyme inhibitor and a prodrug used for the treatment of hypertension.	3.23	1	0	dicarboxylic acid monoester; dipeptide; ethyl ester; organic heterobicyclic compound; secondary amino compound; tertiary carboxamide	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; prodrug
pregabalin Pregabalin: A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.. pregabalin : A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.	3.23	1	0	gamma-amino acid	anticonvulsant; calcium channel blocker
alvimopan anhydrous alvimopan: mu opioid receptor antagonist; intended to treat constipation in patients taking opiates for pain	3.23	1	0	peptide
aliskiren aliskiren: orally active nonpeptidic renin inhibitor. aliskiren : A monomethoxybenzene compound having a 3-methoxypropoxy group at the 2-position and a multi-substituted branched alkyl substituent at the 4-position.	3.23	1	0	monocarboxylic acid amide; monomethoxybenzene	antihypertensive agent
vx680 [no description available]	5.89	9	0	N-arylpiperazine
famotidine [no description available]	3.23	1	0	1,3-thiazoles; guanidines; sulfonamide	anti-ulcer drug; H2-receptor antagonist; P450 inhibitor
fenoterol fenoterol hydrobromide : The hydrobromide salt of fenoterol. A beta2-adrenergic agonist, it is used as a bronchodilator in the management of reversible airway obstruction.	2.63	2	0	hydrobromide	beta-adrenergic agonist; bronchodilator agent; sympathomimetic agent
bafilomycin a [no description available]	2.15	1	0
xib 4035 XIB 4035: a GFRalpha-1 agonist; structure in first source	2.89	3	0
cefotaxime Cefotaxime: Semisynthetic broad-spectrum cephalosporin.. cefotaxime : A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.	3.23	1	0	1,3-thiazoles; cephalosporin; oxime O-ether	antibacterial drug; drug allergen
aztreonam [no description available]	3.23	1	0	beta-lactam antibiotic allergen; monobactam	antibacterial drug; drug allergen; EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
viroxime [no description available]	2.41	1	0
gw-5074 [no description available]	2.21	1	0
bisabolol bisabolol: monocyclic sesquiterpene alcohol with strong bacteriocidal effects, especilly against M. Tuberc.; isolated from seed plant Populus tacamacaha; RN given refers to cpd without isomeric desigation	2.07	1	0
proguanil Proguanil: A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.. proguanil : A biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, which is involved in the reproduction of the malaria parasites Plasmodium falciparum and P. vivax within the red blood cells.	3.51	1	0	biguanides; monochlorobenzenes	antimalarial; antiprotozoal drug; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
ro 42-5892 remikiren : An L-histidine derivative that is L-histidine in which one of the amino hydrogens is replaced by a (2S)-2-[(2-methylpropane-2-sulfonyl)methyl]-3-phenylpropanoyl group and the carboxy group is replaced by a [(2S,3R,4S)-1-cyclohexyl-4-cyclopropyl-3,4-dihydroxybutan-2-yl]amino group. It is a renin inhibitor which was under development for the treatment of hypertension (now discontinued).	2.21	1	0	cyclopropanes; diol; L-histidine derivative; secondary carboxamide; sulfone	antihypertensive agent; EC 3.4.23.15 (renin) inhibitor; peptidomimetic; vasodilator agent
cefpodoxime [no description available]	3.23	1	0	carboxylic acid; cephalosporin	antibacterial drug
palonosetron Palonosetron: Isoquinoline and quinuclidine derivative that acts as a 5-HT3 RECEPTOR antagonist. It is used in the prevention of nausea and vomiting induced by cytotoxic chemotherapy, and for the prevention of post-operative nausea and vomiting.. palonosetron : An organic heterotricyclic compound that is an antiemetic used (as its hydrochloride salt) in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy.	3.23	1	0	azabicycloalkane; delta-lactam; organic heterotricyclic compound	antiemetic; serotonergic antagonist
d 4476 [no description available]	2.08	1	0	imidazoles
cyc 116 4-methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-amine: an aurora kinase inhibitor; structure in first source	2.81	3	0
bay 19-8004 BAY 19-8004: a PDE4 inhibitor; structure in first source	2.08	1	0
rifaximin [no description available]	3.23	1	0	acetate ester; cyclic ketal; lactam; macrocycle; organic heterohexacyclic compound; rifamycins; semisynthetic derivative	antimicrobial agent; gastrointestinal drug; orphan drug
bafilomycin a1 bafilomycin A1: from Streptomyces griseus; structure given in first source. bafilomycin A1 : The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.	2.05	1	0	cyclic hemiketal; macrolide antibiotic; oxanes	apoptosis inducer; autophagy inhibitor; bacterial metabolite; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor; ferroptosis inhibitor; fungicide; potassium ionophore; toxin
everolimus [no description available]	5.85	11	0	cyclic acetal; cyclic ketone; ether; macrolide lactam; primary alcohol; secondary alcohol	anticoronaviral agent; antineoplastic agent; geroprotector; immunosuppressive agent; mTOR inhibitor
laq824 LAQ824: Histone deacetylase inhibitor	3.41	1	0
ixabepilone [no description available]	3.58	2	0	1,3-thiazoles; beta-hydroxy ketone; epoxide; lactam; macrocycle	antineoplastic agent; microtubule-destabilising agent
ekb 569 EKB 569: an EGF receptor kinase inhibitor	2.54	2	0	aminoquinoline; monocarboxylic acid amide; monochlorobenzenes; nitrile	protein kinase inhibitor
axitinib [no description available]	3.02	4	0	aryl sulfide; benzamides; indazoles; pyridines	antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist
pai 039 tiplaxtinin: inhibitor of plasminogen activator inhibitor-1	2.08	1	0	indole-3-acetic acids
rilpivirine [no description available]	3.51	1	0	aminopyrimidine; nitrile	EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor; HIV-1 reverse transcriptase inhibitor
belotecan belotecan: structure in first source	2.89	3	0	pyranoindolizinoquinoline
tanespimycin CP 127374: analog of herbimycin A	2.03	1	0	1,4-benzoquinones; ansamycin; carbamate ester; organic heterobicyclic compound; secondary amino compound	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor
ceftizoxime [no description available]	3.23	1	0	cephalosporin	antibacterial drug
1-methyl-d-lysergic acid butanolamide [no description available]	3.23	1	0	ergot alkaloid; monocarboxylic acid amide	serotonergic antagonist; sympatholytic agent; vasoconstrictor agent
norgestimate [no description available]	2.89	3	0	ketoxime; steroid ester; terminal acetylenic compound	contraceptive drug; progestin; synthetic oral contraceptive
b 43 RK-24466 : A member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively).	2.89	3	0	aromatic amine; aromatic ether; cyclopentanes; primary amino compound; pyrrolopyrimidine	EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector
gw2974 GW2974: quinazoline derivative, which is able to block the activation of both the EGFR and erbB2	2.08	1	0	pyridopyrimidine
4-(2' methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-fluorobenzamido)ethyl)piperazine [no description available]	2.89	3	0
nitrofurantoin Nitrofurantoin: A urinary anti-infective agent effective against most gram-positive and gram-negative organisms. Although sulfonamides and antibiotics are usually the agents of choice for urinary tract infections, nitrofurantoin is widely used for prophylaxis and long-term suppression.. nitrofurantoin : An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA.	3.23	1	0	imidazolidine-2,4-dione; nitrofuran antibiotic; organonitrogen heterocyclic antibiotic; organooxygen heterocyclic antibiotic	antibacterial drug; antiinfective agent; hepatotoxic agent
methiazole methiazole: a parasitostatic agent	2.89	3	0	benzimidazoles; carbamate ester
sb 218795 SB 218795: structure in first source	2.89	3	0	quinolines
bvt.948 [no description available]	2.89	3	0
ca 074 methyl ester [no description available]	2.15	1	0
nifurtimox Nifurtimox: A nitrofuran thiazine that has been used against TRYPANOSOMIASIS.	3.16	1	0	nitrofuran antibiotic
ispinesib [no description available]	2.53	2	0	benzamides
6 beta-hydroxycortisol 6 beta-hydroxycortisol: RN given refers to the (6beta,11beta)-isomer; see also record for 6 alpha-hydrocortisol. 6beta-hydroxycortisol : A C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo.	3.45	1	1	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; 6beta-hydroxy steroid; C21-steroid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	human metabolite; mammalian metabolite; probe
eritoran eritoran : A lipid A derivative used for the treatment of severe sepsis.	2.21	1	0	lipid As
dantrolene [no description available]	3.23	1	0
fk 866 N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide: inhibits nicotinamide phosphoribosyltransferase; structure in first source	2.21	1	0	benzamides; N-acylpiperidine
cefdinir [no description available]	3.23	1	0	cephalosporin; ketoxime	antibacterial drug
etonogestrel [no description available]	3.23	1	0	17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; terminal acetylenic compound	contraceptive drug; female contraceptive drug; progestin
a 38503 [no description available]	2.89	3	0
temsirolimus [no description available]	3.91	3	0	macrolide lactam
dutasteride Dutasteride: A 5-ALPHA-REDUCTASE INHIBITOR that is reported to inhibit both type-1 and type2 isoforms of the enzyme and is used to treat BENIGN PROSTATIC HYPERPLASIA.. dutasteride : An aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland.	3.23	1	0	(trifluoromethyl)benzenes; aza-steroid; delta-lactam	antihyperplasia drug; EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
pd 184352 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide: inhibits MAP kinase kinase; structure in first source	4.45	6	0	aminobenzoic acid
retapamulin retapamulin: a synthetic pleuromutilin	2.17	1	0	carbotricyclic compound; carboxylic ester; cyclic ketone
isavuconazole isavuconazole : A 1,3-thiazole that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,5-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively. It is an antifungal drug used for the treatment of invasive aspergillosis and invasive mucormycosis.	3.51	1	0	1,3-thiazoles; conazole antifungal drug; difluorobenzene; nitrile; tertiary alcohol; triazole antifungal drug	EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; ergosterol biosynthesis inhibitor; orphan drug
lu 208075 ambrisentan: an ET(A) receptor antagonist and antihypertensive agent; studied for use in pulmonary arterial hypertension	3.23	1	0	diarylmethane
bibx 1382bs BIBX 1382BS: an ErbB receptor kinase inhibitor; no further information available 4/2001	3.94	3	0	substituted aniline
vildagliptin [no description available]	2.17	1	0	amino acid amide
fesoterodine fesoterodine: a muscarinic antagonist for treatment of overactive bladder	3.23	1	0	diarylmethane
on 01910 ON 01910: a Plk1 inhibitor with antineoplastic activity; structure in first source. N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine : A glycine derivative that is glycine in which one of the hydrogens of the amino group is substituted by a 2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl group.. rigosertib : An N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties.	2.15	1	0	N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine	antineoplastic agent; apoptosis inducer; EC 2.7.11.21 (polo kinase) inhibitor; microtubule-destabilising agent
panobinostat Panobinostat: An indole and hydroxamic acid derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used as an antineoplastic agent in combination with BORTEZOMIB and DEXAMETHASONE for the treatment of MULTIPLE MYELOMA.. panobinostat : A hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma.	4.37	3	0	cinnamamides; hydroxamic acid; methylindole; secondary amino compound	angiogenesis modulating agent; antineoplastic agent; EC 3.5.1.98 (histone deacetylase) inhibitor
hdac-42 HDAC-42: structure in first source	2.08	1	0	amidobenzoic acid
staurosporine staurosporinium : Conjugate acid of staurosporine.	5.79	11	0	ammonium ion derivative
parthenolide [no description available]	2.58	2	0	sesquiterpene lactone	drug allergen; inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug
krn 633 N-(2-chloro-4-((6,7-dimethoxy-4-quinazolinyl)oxy)phenyl)-N'-propylurea: a VEGF receptor-2 tyrosine kinase inhibitor; structure in first source	2.89	3	0
[4-[[4-(1-benzothiophen-2-yl)-2-pyrimidinyl]amino]phenyl]-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone [no description available]	2.08	1	0	benzamides; N-acylpiperidine
s 1743 Esomeprazole: The S-isomer of omeprazole.. esomeprazole : A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.	3.44	1	1	magnesium salt	anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
gemifloxacin Gemifloxacin: A naphthyridine and fluoroquinolone derivative antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used for the treatment of community-acquired pneumonia and acute bacterial infections associated with chronic bronchitis.. gemifloxacin : A 1,4-dihydro-1,8-naphthyridine with a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a substituted pyrrolin-1-yl group at the 7-position.	3.23	1	0	1,8-naphthyridine derivative; fluoroquinolone antibiotic; monocarboxylic acid; quinolone antibiotic	antibacterial drug; antimicrobial agent; topoisomerase IV inhibitor
dexlansoprazole Dexlansoprazole: The R-isomer of lansoprazole that is used to treat severe GASTROESOPHAGEAL REFLUX DISEASE.	3.23	1	0	benzimidazoles; sulfoxide
fosinopril [no description available]	3.23	1	0
vacuolin-1 vacuolin-1: inhibits Ca2-dependent lysosomal exocytosis	3.92	2	0
armodafinil armodafinil : A 2-[(diphenylmethyl)sulfinyl]acetamide that has R configuration at the sulfur atom. Like its racemate, modafinil, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. Peak concentration in the blood later occurs later following administration than with modafinil, so it is thought that armodafinil may be more effective than modafinil in treating people with excessive daytime sleepiness.	3.23	1	0	2-[(diphenylmethyl)sulfinyl]acetamide	central nervous system stimulant; eugeroic
5-amino-4-oxo-3-phenyl-1-thieno[3,4-d]pyridazinecarboxylic acid [no description available]	2.89	3	0	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
iniparib [no description available]	2.08	1	0	carbonyl compound; organohalogen compound
mk 0752 [no description available]	2.08	1	0
gw 501516 GW 501516: a selective PPARdelta agonist; structure in first source. GW 501516 : An aromatic ether that is phenoxyacetic acid in which the phenyl group is substituted at position 2 by a methyl group and at position 4 by a (1,3-thiazol-5-ylmethyl)sulfanediyl group, and in which the 1,3-thiazolyl group is substituted at positions 2 and 4 by p-trifluoromethylphenyl and methyl groups, respectively.	3.07	4	0	1,3-thiazoles; aromatic ether; aryl sulfide; monocarboxylic acid; organofluorine compound	carcinogenic agent; PPARbeta/delta agonist
av 412 [no description available]	2.52	2	0
ag-041r AG-041R: structure in first source	2.08	1	0
telatinib [no description available]	2.52	2	0
y-39983 Y-39983: SNJ-1656 is an ophthalmic solution of Y-39983; ROCK (rho kinase) inhibitor, promotes regeneration of crushed axons of retinal ganglion cells; structure in first source	2.15	1	0	pyrrolopyridine
dolastatin 10 dolastatin 10: from mollusk Dolabella auricularia; contains four amino acids, dolavaline, dolaisoleucine, dolaproine, valine and the primary amine dolaphenine; deo-dolastatin 10 is a new dolastatin 10 chiral derivative with MW of 784. dolastatin 10 : A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization.	2.89	3	0	1,3-thiazoles; tetrapeptide	animal metabolite; antineoplastic agent; apoptosis inducer; marine metabolite; microtubule-destabilising agent
cp 547632 3-(4-bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide: inhibits vascular endothelial growth factor receptor-2 tyrosine kinase; structure in first source	2.8	3	0
timcodar timcodar: a mutlidrug resistance inhibitor; structure in first source	3.51	1	0
bms345541 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline: structure in first source	2.06	1	0	quinoxaline derivative
spc-839 SPC-839: an inhibitor of activator protein 1; structure in first source	3.07	4	0
lenvatinib lenvatinib : A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine.	2.81	3	0	aromatic amide; aromatic ether; cyclopropanes; monocarboxylic acid amide; monochlorobenzenes; phenylureas; quinolines	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist; orphan drug; vascular endothelial growth factor receptor antagonist
andarine [no description available]	2.08	1	0	acetamides; anilide
gw843682x [no description available]	2.08	1	0	(trifluoromethyl)benzenes
pd 0325901 mirdametinib: has antineoplastic activity; appears to be a MEK inhibitor. PD 0325901 : A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position 2 by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).	3.03	4	0	difluorobenzene; hydroxamic acid ester; monofluorobenzenes; organoiodine compound; propane-1,2-diols; secondary amino compound	antineoplastic agent; EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
midostaurin midostaurin : An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.	6.22	17	0	benzamides; gamma-lactam; indolocarbazole; organic heterooctacyclic compound	antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor
sincalide Sincalide: An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.	3.23	1	0	oligopeptide
tapentadol Tapentadol: An opioid analgesic, MU OPIOID RECEPTOR agonist, and noradrenaline reuptake inhibitor that is used in the treatment of moderate to severe pain, and of pain associated with DIABETIC NEUROPATHIES.	3.23	1	0	alkylbenzene
ag 14361 [no description available]	2.08	1	0	benzimidazoles
sb 265610 [no description available]	2.08	1	0
px-866 PX-866: inhibitor of phosphoinositide-3-kinase signaling with antitumor activity; structure in first source. PX-866 : An organic heterotetracyclic compound that is obtained from wortmanin via aminolysis of its furan ring by diallyl amine.	2.15	1	0	acetate ester; delta-lactone; organic heterotetracyclic compound; tertiary amino compound	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
valnemulin [no description available]	2.63	2	0
gambogic acid gambogic acid: RN given refers to (1R-(1alpha,1(Z),3abeta,5alpha,11beta,14aS*))-isomer	3.51	1	0	pyranoxanthones	metabolite
bms201038 BMS201038: an anticholesteremic agent and microsomal triglycide transfer protein inhibitor. lomitapide : A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.	2.25	1	0	(trifluoromethyl)benzenes; benzamides; fluorenes; piperidines	anticholesteremic drug; MTP inhibitor
pentagastrin Pentagastrin: A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.	3.23	1	0	organic molecular entity
nu 7026 2-(morpholin-4-yl)benzo(h)chromen-4-one: a radiosensitizing agent that inhibits DNA-dependent protein kinase; structure in first source	2.89	3	0	organic heterotricyclic compound; organooxygen compound
ripasudil [no description available]	2.15	1	0	isoquinolines
fr 148083 5Z-7-oxozeaenol : A macrolide that is the 7-oxo derivative of zeaenol (the 5Z stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB.	3.66	2	0	aromatic ether; macrolide; phenols; secondary alcohol; secondary alpha-hydroxy ketone	antibacterial agent; antineoplastic agent; metabolite; NF-kappaB inhibitor
mocetinostat mocetinostat: undergoing phase II clinical trials for treatment of cancer. mocetinostat : A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).	2.08	1	0	aminopyrimidine; benzamides; pyridines; secondary amino compound; secondary carboxamide; substituted aniline	antineoplastic agent; apoptosis inducer; autophagy inducer; cardioprotective agent; EC 3.5.1.98 (histone deacetylase) inhibitor; hepatotoxic agent
osi 930 OSI 930: inhibits both receptor tyrosine kinase Kit and kinase insert domain receptor; structure in first source	3.25	5	0	aromatic amide
cgp 74588 CGP 74588: a metabolite of STI-571; structure in first source	2.48	2	0	benzamides
ki 20227 [no description available]	2.48	2	0
cefditoren cefditoren: structure given in first source; RN given refers to the (6R-(3(Z),6alpha,7beta(Z)))-isomer. cefditoren : A broad spectrum, third-generation cephalosporin antibiotic with (Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. Generally administered as its orally absorbed pivaloyloxymethyl ester prodrug, it is used for the treatment of mild to moderate infections caused by susceptible strains of microorganisms in acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections.	3.23	1	0	carboxylic acid; cephalosporin	antibacterial drug
scio-469 SCIO-469: a small-molecule p38 mitogen-activated protein (MAP) kinase inhibitor for potential oral therapy for inflammatory disorders; in phase lib clinical trials for rheumatoid arthritis 4/2004. talmapimod : An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.	2.52	2	0	aromatic amide; aromatic ketone; chloroindole; dicarboxylic acid diamide; indolecarboxamide; monofluorobenzenes; N-acylpiperazine; N-alkylpiperazine	antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
ticagrelor Ticagrelor: An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.. ticagrelor : A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome.	2.89	3	0	aryl sulfide; hydroxyether; organofluorine compound; secondary amino compound; triazolopyrimidines	P2Y12 receptor antagonist; platelet aggregation inhibitor
ssr 69071 SSR 69071: structure in first source	2.08	1	0	pyridopyrimidine
l 692585 [no description available]	2.89	3	0	peptide
cp 724714 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide: CP-724714 is the ((2E)-isomer, 1:1.5 succinate); structure in first source	2.54	2	0	2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide	antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; hepatotoxic agent
rivaroxaban Rivaroxaban: A morpholine and thiophene derivative that functions as a FACTOR XA INHIBITOR and is used in the treatment and prevention of DEEP-VEIN THROMBOSIS and PULMONARY EMBOLISM. It is also used for the prevention of STROKE and systemic embolization in patients with non-valvular ATRIAL FIBRILLATION, and for the prevention of atherothrombotic events in patients after an ACUTE CORONARY SYNDROME.. rivaroxaban : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.	2.21	1	0	aromatic amide; lactam; monocarboxylic acid amide; morpholines; organochlorine compound; oxazolidinone; thiophenes	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor
treosulfan treosulfan: immunosuppressant; RN given refers to (S-(R,R))-isomer	2.1	1	0	methanesulfonate ester
pi103 PI103: pyridofuropyrimidine antineoplastic; a potent inhibitor of class I phosphatidylinositide 3-kinases (PI3K); structure in first soruce	3.23	5	0	aromatic amine; morpholines; organic heterotricyclic compound; phenols; tertiary amino compound	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
sb 210313 [no description available]	2.08	1	0
hmn-214 (E)-4-(2-(2-(N-acetyl-N-(4-methoxybenzenesulfonyl)amino)stilbazole)) 1-oxide: an antineoplastic agent; structure in first source	2.15	1	0
gw 4064 [no description available]	2.08	1	0	stilbenoid
nnc 26-9100 NNC 26-9100: structure in first source	2.89	3	0	aminopyridine
2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine [no description available]	2.89	3	0
sa 4503 [no description available]	2.08	1	0
ic 87114 IC 87114: structure in first source	2.08	1	0	6-aminopurines; biaryl; quinazolines	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
zibotentan ZD4054: a potent endothelin receptor A antagonist that inhibits ovarian carcinoma cell proliferation	2.08	1	0	phenylpyridine
tivozanib N-(2-chloro-4-((6,7-dimethoxy-4-quinolyl)oxy)phenyl)-N'-(5-methyl-3-isoxazolyl)urea: KNR-951 is the HCl, monohydrate salt; an antineoplastic agent; structure in first source	4.65	7	0	aromatic ether
hki 272 [no description available]	3.21	5	0	nitrile; quinolines	antineoplastic agent; tyrosine kinase inhibitor
tofacitinib tofacitinib : A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis.	3.04	4	0	N-acylpiperidine; nitrile; pyrrolopyrimidine; tertiary amino compound	antirheumatic drug; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
bibr 1532 [no description available]	2.08	1	0
n-(6-chloro-7-methoxy-9h-beta-carbolin-8-yl)-2-methylnicotinamide [no description available]	3.23	5	0
rucaparib AG14447: Poly(ADP-ribose) polymerase inhibitor; structure in first source	2.08	1	0	azepinoindole; caprolactams; organofluorine compound; secondary amino compound	antineoplastic agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
cediranib [no description available]	2.78	3	0	aromatic ether
tae226 TAE226: an adhesion kinase inhibitor, offers an attractive therapeutic approach in ovarian carcinoma; structure in first source	2.89	3	0	morpholines
gw0742 GW 610742: structure in first source	3.07	4	0	monocarboxylic acid
ap23464 AP23464: a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases	3.13	1	0
6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-n-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6s)- [no description available]	3.41	1	0	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
ps1145 PS1145: IkappaB kinase inhibitor; structure in first source	2.08	1	0	beta-carbolines
l-779,450 L-779,450: B-Raf kinase inhibitor; structure in first source	2.04	1	0	imidazoles
bay 41-8543 BAY 41-8543: structure in first source	2.08	1	0	pyrazolopyridine
u 18666a 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one: inhibits cycloartenol synthase. 3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride : A hydrochloride obtained by reaction of 3beta-(2-diethylaminoethoxy)androst-5-en-17-one with one equivalent of hydrochloric acid. It is a cholesterol synthesis and transport inhibitor.	2.89	3	0	hydrochloride	antiviral agent; EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor; Hedgehog signaling pathway inhibitor; nicotinic antagonist; sterol biosynthesis inhibitor
chir 99021 Chir 99021: structure in first source. CHIR 99021 : A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.	2.08	1	0	aminopyridine; aminopyrimidine; cyanopyridine; diamine; dichlorobenzene; imidazoles; secondary amino compound	EC 2.7.11.26 (tau-protein kinase) inhibitor
ym 201636 6-amino-N-(3-(4-(4-morpholinyl)pyrido(3',2'-4,5)furo(3,2-d)pyrimidin-2-yl)phenyl)-3-pyridinecarboxamide: an antiviral agent; structure in first source	3.51	1	0	aromatic amide
sb 525334 6-(2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline: a TGF-betaR kinase inhibitor	3.07	4	0	quinoxaline derivative
way-362450 [no description available]	2.08	1	0	indoles
osu 03012 OSU 03012: a PDK-1 inhibitor; structure in first source	2.41	1	0	antibiotic antifungal drug; aromatic amide; glycine derivative; organofluorine compound; phenanthrenes; pyrazoles	antineoplastic agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
masitinib [no description available]	5.4	7	0	1,3-thiazoles; benzamides; N-alkylpiperazine; pyridines	antineoplastic agent; antirheumatic drug; tyrosine kinase inhibitor
bx795 BX795: structure in first source	3.28	5	0	ureas
ly-2157299 LY-2157299: an orally active transforming growth factor beta receptor (TGF-beraR) kinase inhibitor. LY-2157299 : A pyrrolopyrazole that is 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole which is substituted at positions 2 and 3 by 6-methylpyridin-2-yl and 6-(aminocarbonyl)quinolin-4-yl groups, respectively. A Transforming growth factor-betaRI (TGF-betaRI) kinase inhibitor, it blocks TGF-beta-mediated tumor growth in glioblastoma.	2.15	1	0	aromatic amide; methylpyridines; monocarboxylic acid amide; pyrrolopyrazole; quinolines	antineoplastic agent; TGFbeta receptor antagonist
pazopanib pazopanib: a protein kinase inhibitor. pazopanib : A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer.	5.85	11	0	aminopyrimidine; indazoles; sulfonamide	angiogenesis modulating agent; antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist
sepantronium sepantronium: a survivin suppressant with antineoplastic activity. sepantronium : An organic cation that is 1-(2-methoxyethyl)-2-methyl-1H-naphtho[2,3-d]imidazole-4,9-dione in which the nitrogen at position 3 of the napthoimidazole moiety has been alkylated by a pyrazin-2-ylmethyl group.	2.08	1	0	organic cation
azd 6244 AZD 6244: a MEK inhibitor	4.85	9	0	benzimidazoles; bromobenzenes; hydroxamic acid ester; monochlorobenzenes; organofluorine compound; secondary amino compound	anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
su 14813 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide: has both antineoplastic and antiangiogenic activities; structure in first source	2.5	2	0
prasugrel hydrochloride Prasugrel Hydrochloride: A piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those undergoing PERCUTANEOUS CORONARY INTERVENTIONS.. prasugrel hydrochloride : A racemate comprising equal amounts of (R)- and (S)-prasugrel hydrochloride. Used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.	3.23	1	0
1-(2-(1-adamantyl)ethyl)-1-pentyl-3-(3-(4-pyridyl)propyl)urea 1-(2-(1-adamantyl)ethyl)-1-pentyl-3-(3-(4-pyridyl)propyl)urea: structure in first source	3.07	4	0
a 443654 A 443654: an Akt kinase inhibitor; structure in first source	2.41	1	0	indoles
apilimod [no description available]	3.92	2	0
bibw 2992 [no description available]	2.81	3	0	aromatic ether; enamide; furans; monochlorobenzenes; organofluorine compound; quinazolines; secondary carboxamide; tertiary amino compound	antineoplastic agent; tyrosine kinase inhibitor
bay 61-3606 [no description available]	2.89	3	0	pyrimidines
N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide : A member of the class of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-4-carboxylic acid with the amino group of 3-cyanoaniline.	2.08	1	0	1,3,4-oxadiazoles; benzamides; biphenyls; nitrile	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
ar c155858 AR C155858: an MCT1 inhibitor; structure in first source	2.08	1	0
pik 75 PIK 75: structure in first source	2.41	1	0
binimetinib binimetinib : A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-fluorophenyl)nitrilo, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor (IC50= 12 nM). Approved by the FDA for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation in combination with encorafenib.	2.53	2	0	benzimidazoles; bromobenzenes; hydroxamic acid ester; monofluorobenzenes; secondary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sotrastaurin sotrastaurin: a potent protein kinase C-selective inhibitor; structure in first source. sotrastaurin : A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.	2.15	1	0	indoles; maleimides; N-alkylpiperazine; N-arylpiperazine; quinazolines	anticoronaviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunosuppressive agent
aee 788 AEE 788: structure in first source	4.12	4	0	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; epidermal growth factor receptor antagonist; trypanocidal drug
saracatinib [no description available]	5.16	7	0	aromatic ether; benzodioxoles; diether; N-methylpiperazine; organochlorine compound; oxanes; quinazolines; secondary amino compound	anticoronaviral agent; antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; radiosensitizing agent
alpha-synuclein alpha-Synuclein: A synuclein that is a major component of LEWY BODIES and plays a role in SYNUCLEINOPATHIES, neurodegeneration and neuroprotection.	6.74	8	1
sd-208 [no description available]	3.07	4	0
on012380 ON012380: a non-ATP-competitive inhibitor of BCR-ABL; structure in first source	4.05	2	0
ko 143 [no description available]	3.66	2	0	beta-carbolines; tert-butyl ester
vx 702 VX 702: a p38 MAP kinase inhibitor	2.52	2	0	phenylpyridine
crenolanib [no description available]	3.41	6	0	aminopiperidine; aromatic ether; benzimidazoles; oxetanes; quinolines; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
tg100-115 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol: for treatment of ischemia reperfusion injury; structure in first source	2.5	2	0	pteridines
cj 033466 CJ 033466: structure in first source	2.89	3	0
cc 401 CC 401: an anthrapyrazolone	3.1	4	0	pyrazoles; ring assembly
bms 599626 [no description available]	2.15	1	0
exel-7647 tesevatinib : A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties.	2.54	2	0
volasertib BI 6727: a polo-like kinase inhibitor with broad antitumor activity; structure in first source	3.91	3	0
pha 665752 [no description available]	2.06	1	0	dichlorobenzene; enamide; indolones; N-acylpyrrolidine; pyrrolecarboxamide; secondary carboxamide; sulfone; tertiary carboxamide	antineoplastic agent; c-Met tyrosine kinase inhibitor
PB28 PB28 : A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.	3.07	4	0	aromatic ether; piperazines; tetralins	anticoronaviral agent; antineoplastic agent; apoptosis inducer; sigma-2 receptor agonist
arterolane arterolane: a trioxolane with antimalarial activity; structure in first source. arterolane : An oxaspiro compound that is dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.1(3,7)]decane] substituted by a 2-[(2-amino-2-methylpropyl)amino]-2-oxoethyl group at position 4s. Its maleic acid salt is used as an antimalarial drug in combination with piperaquine.	2.89	3	0
oxadiazoles Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms.	2.13	1	0
baci-im [no description available]	3.23	1	0	homodetic cyclic peptide; polypeptide; zwitterion	antibacterial agent; antimicrobial agent
azd 7762 [no description available]	2.52	2	0	aromatic amide; thiophenes
cariprazine cariprazine: Structure in first source. cariprazine : An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.	2.89	3	0
krp-203 [no description available]	3.07	4	0
mk 0354 [no description available]	2.08	1	0
regorafenib [no description available]	5.49	10	0	(trifluoromethyl)benzenes; aromatic ether; monochlorobenzenes; monofluorobenzenes; phenylureas; pyridinecarboxamide	antineoplastic agent; hepatotoxic agent; tyrosine kinase inhibitor
at 7867 [no description available]	2.89	3	0	monochlorobenzenes; piperidines; pyrazoles	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
acetic acid 2-[4-methyl-8-(4-morpholinylsulfonyl)-1,3-dioxo-2-pyrrolo[3,4-c]quinolinyl]ethyl ester [no description available]	3.07	4	0	pyrroloquinoline
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one [no description available]	3.02	4	0	methoxybenzenes; substituted aniline
ptc 124 [no description available]	2.89	3	0	oxadiazole; ring assembly
degrasyn degrasyn: a JAK2 kinase inhibitor that induces rapid degradation of c-Myc protein in MM-1 multiple myeloma and other tumor cell lines; structure in first source	2.63	2	0
abt-737 [no description available]	2.52	2	0	aromatic amine; aryl sulfide; biphenyls; C-nitro compound; monochlorobenzenes; N-arylpiperazine; N-sulfonylcarboxamide; secondary amino compound; tertiary amino compound	anti-allergic agent; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
brivanib [no description available]	2.78	3	0	aromatic ether; diether; fluoroindole; pyrrolotriazine; secondary alcohol	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; drug metabolite; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist
icg 001 [no description available]	2.08	1	0	peptide
bms 477118 [no description available]	3.23	1	0	adamantanes; azabicycloalkane; monocarboxylic acid amide; nitrile; tertiary alcohol	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; hypoglycemic agent
mp470 [no description available]	2.52	2	0	N-arylpiperazine
rgb 286638 [no description available]	2.15	1	0
nystatin a1 Nystatin: Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Streptomyces species. The biologically active components of the complex are nystatin A1, A2, and A3.. nystatin : A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections.. nystatin A1 : A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species.	3.23	1	0	nystatins
np 031112 tideglusib: an NSAID and neuroprotective agent. tideglusib : A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy.	2.15	1	0	benzenes; naphthalenes; thiadiazolidine	anti-inflammatory agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; neuroprotective agent
nu 7441 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one: structure in first source	3.61	2	0	dibenzothiophenes
at 7519 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-pyrazole-3-carboxamide : A member of the class of pryrazoles that is 4-amino-1H-pyrazole-3-carboxylic acid in which the primary amino group has been acylated by a 2,6-dichlorobenzoyl group and in which the carboxylic acid has been converted into a carboxamide by formal condensation with the primary amino group of 4-aminopiperidine.	2.78	3	0	dichlorobenzene; piperidines; pyrazoles; secondary carboxamide	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
bms-690514 [no description available]	2.83	3	0
bi 2536 [no description available]	5.03	11	0
4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide [no description available]	3.25	1	0	biphenyls
inno-406 [no description available]	7.11	14	0	biaryl
nvp-ast487 NVP-AST487: antineoplastic; a RET kinase inhibitor that blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells	2.06	1	0
kw 2449 KW 2449: has both multikinase inhibitory activity and antineoplastic activity; structure in first source	3.93	3	0
nutlin-3a nutlin 3: an MDM2 antagonist; structure in first source	2.57	2	0	stilbenoid
danusertib [no description available]	2.52	2	0	piperazines
N-[4-(2-tert-butylphenyl)sulfonylphenyl]-2,3,4-trihydroxy-5-[(2-propan-2-ylphenyl)methyl]benzamide [no description available]	2.08	1	0	benzamides
N-[5-[[5-[(4-acetyl-1-piperazinyl)-oxomethyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[(3,3-dimethylbutan-2-ylamino)methyl]benzamide [no description available]	2.08	1	0	benzamides
nvp-aew541 [no description available]	2.13	1	0
abt 869 [no description available]	2.78	3	0	aromatic amine; indazoles; phenylureas	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
azd 8931 sapitinib : A member of the class of quinazolines that is 4-amino-7-methoxyquinazoline in which the amino group has been substituted by a 3-chloro-2-fluorophenyl group and in which position 6 of the quinoline ring has been substituted by a {1-[2-(methylamino)-2-oxoethyl]piperidin-4-yl}oxy group. Sapitinib is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3.	2.15	1	0	aromatic ether; monochlorobenzenes; monofluorobenzenes; piperidines; quinazolines; secondary amino compound; tertiary amino compound	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; epidermal growth factor receptor antagonist
arq 197 [no description available]	3.65	2	0	indoles
azd 1152 AZD-1152 : A member of the of quinazolines that is 4-aminoquinazolin-7-ol in which the amino group at position 4 has been substituted by a 5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl group, while the hydroxy group at position 7 has been converted into the corresponding 3-[ethyl(2-hydroxyethyl)aminopropyl ether.	3.1	4	0	anilide; monoalkyl phosphate; monofluorobenzenes; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor; prodrug
pf 00299804 dacomitinib: a pan-ERBB inhibitor. dacomitinib : A member of the class of quinazolines that is 7-methoxyquinazoline-4,6-diamine in which the amino group at position 4 is substituted by a 3-chloro-4-fluorophenyl group and the amino group at position 6 is substituted by an (E)-4-(piperidin-1-yl)but-2-enoyl group.	3.73	2	0	enamide; monochlorobenzenes; monofluorobenzenes; piperidines; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
ridaforolimus [no description available]	2.15	1	0	macrolide lactam
dorsomorphin dorsomorphin: an AMPK inhibitor. dorsomorphin : A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine which is substituted at positions 3 and 6 by pyridin-4-yl and p-[2-(piperidin-1-yl)ethoxy]phenyl groups, respectively. It is a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase, EC 2.7.11.31) and a selective inhibitor of bone morphogenetic protein (BMP) signaling.	3.66	2	0	aromatic ether; piperidines; pyrazolopyrimidine; pyridines	bone morphogenetic protein receptor antagonist; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
ac 261066 [no description available]	2.08	1	0
quisinostat [no description available]	3.41	1	0	indoles
ch 4987655 [no description available]	2.15	1	0
6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-n-(2,2-dimethylprpyl)-3-pyridinecarboxamide [no description available]	2.63	2	0	phenylpyridine
carfilzomib [no description available]	3.27	5	0	epoxide; morpholines; tetrapeptide	antineoplastic agent; proteasome inhibitor
gw9508 GW9508: structure in first source	2.08	1	0	aromatic amine
cc-930 [no description available]	2.15	1	0
N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide [no description available]	3.25	1	0	sulfonamide
jnj 26854165 [no description available]	2.08	1	0
pf 573228 6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one: structure in first source	2.08	1	0	quinolines
gw 2580 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine: a cFMS kinase inhibitor; structure in first source	2.8	3	0
tak 285 N-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide: also inhibits HER2; structure in first source	2.15	1	0
milnacipran [no description available]	3.23	1	0	acetamides
idelalisib idelalisib: an antineoplastic agent and p110delta inhibitor; structure in first source. idelalisib : A member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia.	3.41	6	0	aromatic amine; organofluorine compound; purines; quinazolines; secondary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
crizotinib Crizotinib: A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.. crizotinib : A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)	4.92	10	0	3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine	antineoplastic agent; biomarker; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile [no description available]	2.08	1	0	benzimidazoles
4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide Vx-11e: ERK1-2 inhibitor	2.08	1	0	aromatic amide; heteroarene
osi 906 [no description available]	2.81	3	0	cyclobutanes; quinolines
zstk474 ZSTK-474 : A triamino-1,3,5-triazine that is 1,3,5-triazine in which two of the hydrogens have been replaced by morpholin-4-yl groups while the third hydrogen has been replaced by a 2-(difluoromethyl)benzimidazol-1-yl group. It is an inhibitor of phosphatidylinositol 3-kinase.	2.15	1	0	benzimidazoles; morpholines; organofluorine compound; triamino-1,3,5-triazine	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
ly2109761 [no description available]	2.08	1	0
chir-265 [no description available]	2.78	3	0	aromatic ether
motesanib [no description available]	3.38	6	0	pyridinecarboxamide
fostamatinib fostamatinib: a spleen tyrosine kinase (Syk) inhibitor, metabolized to R406	3.73	2	0
az-628 AZ-628: a multikinase inhibitor; structure in first source	2.08	1	0	benzamides
jnj 28312141 [no description available]	2.06	1	0
4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine PF-670462 free base : A member of the class of imidazoles that is 1H-imidazole which is substituted at positions 1, 4, and 5 by cyclohexyl, p-fluorophenyl, and 2-aminopyrimidin-4-yl groups, respectively. It is a selective inhibitor of the delta- and epsilon-isoforms of casein kinase 1 (CK1delta and CK1epsilon).	3.25	1	0	aminopyrimidine; imidazoles; monofluorobenzenes	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
trametinib [no description available]	4.2	4	0	acetamides; aromatic amine; cyclopropanes; organofluorine compound; organoiodine compound; pyridopyrimidine; ring assembly	anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector
mln8054 [no description available]	2.8	3	0	benzazepine
pf-562,271 [no description available]	3.25	5	0	indoles
pha 767491 PHA 767491: a Cdc7 inhibitor; structure in first source	2.41	1	0	pyrrolopyridine
GDC-0879 [no description available]	2.06	1	0	indanes; ketoxime; primary alcohol; pyrazoles; pyridines	antineoplastic agent; B-Raf inhibitor
gliocladin c gliocladin C: structure in first source	2.89	3	0
losartan potassium Erythropoietin: Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.	2.46	2	0
sb 706504 [no description available]	2.89	3	0
jnj-26483327 JNJ-26483327: an orally active macrocyclic tyrosine kinase inhibitor for treatment of patients with advanced solid tumours; in Phase I trial, 9/2010	2.15	1	0
ly2603618 [no description available]	2.15	1	0	ureas
veliparib [no description available]	2.08	1	0	benzimidazoles	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
ku-0060648 [no description available]	3.07	4	0	dibenzothiophenes
scopolamine hydrobromide [no description available]	3.23	1	0
tg100801 [no description available]	2.15	1	0
dactolisib dactolisib: antineoplastic agent that inhibits both phosphatidylinositol 3-kinase and mTOR. dactolisib : An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.	3.38	6	0	imidazoquinoline; nitrile; quinolines; ring assembly; ureas	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
bgt226 BGT226 free base : An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 3-trifluoromethyl-4-(piperazin-1-yl)phenyl group and at position 8 by a 6-methoxypyridin-3-yl group. A dual PI3K/mTOR inhibitor.. BGT226 : The maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor.	3.27	5	0	aromatic ether; imidazoquinoline; N-arylpiperazine; organofluorine compound; pyridines	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
palomid 529 [no description available]	2.08	1	0
erythrosine Erythrosine: A tetraiodofluorescein used as a red coloring in some foods (cherries, fish), as a disclosure of DENTAL PLAQUE, and as a stain of some cell types. It has structural similarity to THYROXINE.. erythrosin B : An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.	2.31	1	0
n-desmethyldanofloxacin N-desmethyldanofloxacin: structure given in first source	2.89	3	0
rabeprazole sodium [no description available]	2.15	1	0	organic sodium salt
tosedostat [no description available]	2.08	1	0	carboxylic ester; hydroxamic acid; secondary carboxamide
3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide [no description available]	3.92	2	0	organochlorine compound
mdv 3100 [no description available]	2.08	1	0	(trifluoromethyl)benzenes; benzamides; imidazolidinone; monofluorobenzenes; nitrile; thiocarbonyl compound	androgen antagonist; antineoplastic agent
ku 60019 [no description available]	2.08	1	0
gsk 461364 GSK 461364: an antineoplastic agent that inhibits polo-like kinase 1	2.78	3	0	(trifluoromethyl)benzenes
n-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide: a MEK inhibitor; structure in first source	2.08	1	0
azd 1152-hqpa AZD2811: has antineoplastic activity; structure in first source	3.06	4	0	anilide; monofluorobenzenes; primary alcohol; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor
CDN1163 CDN1163: a SERCA2 activator with antidiabetic activity; structure in first source. CDN1163 : A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-isopropoxybenzoic acid with the primary amino group of 2-methylquinolin-8-amine. An allosteric activator of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA).	2.89	3	0	aromatic ether; quinolines; secondary carboxamide	SERCA activator
nvp-tae684 [no description available]	2.48	2	0	piperidines
enmd 2076 ENMD 2076: an antiangiogenic agent with aurora kinase inhibitory and antineoplastic activities	2.15	1	0
cytochrome c-t Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.	3.04	4	0
4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-n-(3-(trifluoromethyl)phenyl)benzamide 4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide: structure in first source	2.08	1	0
gsk 269962a [no description available]	3.07	4	0
e 7050 [no description available]	2.54	2	0	aromatic ether
2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-5-yl)-7-pyrido[2,3-d]pyrimidinone [no description available]	2.15	1	0	pyrazolopyridine
tak-901 [no description available]	2.54	2	0
bivalirudin bivalirudin: designed to bind to the alpha-thrombin catalytic site and anion-binding exosite for fibrin(ogen) recognition. bivalirudin : A synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant.	3.23	1	0	polypeptide	anticoagulant; EC 3.4.21.5 (thrombin) inhibitor
enfuvirtide Enfuvirtide: A synthetic 36-amino acid peptide that corresponds to the heptad repeat sequence of HIV-1 gp41. It blocks HIV cell fusion and viral entry and is used with other anti-retrovirals for combination therapy of HIV INFECTIONS and AIDS.. enfuvirtide : A synthetic 36-amino acid peptide consisting of N-acetyltyrosyl, threonyl, seryl, leucyl, isoleucyl, histidyl, seryl, leucyl, isoleucyl, alpha-glutamyl, alpha-glutamyl, seryl, glutaminyl, asparaginyl, glutaminyl, glutaminyl, alpha-glutamyl, lysyl, asparaginyl, alpha-glutamyl, alpha-glutamyl, alpha-glutamyl, leucyl, leucyl, alpha-glutamyl, leucyl, alpha-aspartyl, lysyl, tryptophyl, alanyl, seryl, leucyl, tryptophyl, asparaginyl, tryptophyl, and phenylalaninamide residues joined in sequence. An HIV fusion inhibitor, it was the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection. It interferes with entry of HIV into cells by binding to the gp41 sub-unit of the viral envelope glycoprotein, so inhibiting fusion of viral and cellular membranes.	3.23	1	0
ganirelix [no description available]	3.23	1	0	polypeptide
glucagon Glucagon: A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511). glucagon : A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.	2.21	1	0	peptide hormone
teriparatide [no description available]	3.23	1	0	polypeptide
salmon calcitonin [no description available]	3.23	1	0	heterodetic cyclic peptide; peptide hormone; polypeptide	bone density conservation agent; metabolite
oligonucleotides [no description available]	4.35	3	0
ly-146032 [no description available]	3.23	1	0	heterodetic cyclic peptide; lipopeptide antibiotic; lipopeptide; macrocycle; macrolide	antibacterial drug; bacterial metabolite; calcium-dependent antibiotics
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ilys-prolyl-alaninamide acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide: FE-200486 is the acetate salt	3.23	1	0	polypeptide
c-peptide C-Peptide: The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.	2.11	1	0
exenatide [no description available]	3.23	1	0
a-83-01 A-83-01: an ALK-5 inhibitor; structure in first source	2.08	1	0
3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one [no description available]	2.08	1	0	indoles
vx-770 ivacaftor: a CFTR potentiator; structure in first source. ivacaftor : An aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis.	2.08	1	0	aromatic amide; monocarboxylic acid amide; phenols; quinolone	CFTR potentiator; orphan drug
gdc-0973 cobimetinib: has antineoplastic activity; structure in first source. cobimetinib : A member of the class of N-acylazetidines obtained by selective formal condensation of the carboxy group of 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid with the secondary amino group from the azetidine ring of 3-[(2S)-piperidin-2-yl]azetidin-3-ol. An inhibitor of mitogen-activated protein kinase that is used (as its fumarate salt) in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma.	2.15	1	0	aromatic amine; difluorobenzene; N-acylazetidine; organoiodine compound; piperidines; secondary amino compound; tertiary alcohol	antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
buparlisib NVP-BKM120: a pan class I PI3 kinase inhibitor with antineoplastic activity; structure in first source	3.94	3	0	aminopyridine; aminopyrimidine; morpholines; organofluorine compound	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
azd 1480 [no description available]	2.52	2	0
azd8330 [no description available]	2.63	2	0	pyridinecarboxamide
pha 848125 N,1,4,4-tetramethyl-8-((4-(4-methylpiperazin-1-yl)phenyl)amino)-4,5-dihydro-1H-pyrazolo(4,3-h)quinazoline-3-carboxamide: a cyclin dependent kinase inhibitor	4.54	6	0
ro5126766 RO5126766: a dual MEK/RAF kinase inhibitor. CH5126766 : A member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3.	2.15	1	0	aryloxypyrimidine; coumarins; organofluorine compound; pyridines; sulfamides	antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
tg101209 [no description available]	3.25	1	0	N-alkylpiperazine; N-arylpiperazine; pyrimidines; secondary amino compound; sulfonamide	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
fedratinib fedratinib: a selective small-molecule inhibitor of JAK2	4.32	5	0	sulfonamide
gsk690693 [no description available]	3.02	4	0	1,2,5-oxadiazole; acetylenic compound; aromatic amine; aromatic ether; imidazopyridine; piperidines; primary amino compound; tertiary alcohol	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
cnf 2024 [no description available]	2.08	1	0	2-aminopurines; aromatic ether; organochlorine compound; pyridines	antineoplastic agent; Hsp90 inhibitor
ku 0063794 Ku 0063794: an mTOR inhibitor; structure in first source	2.08	1	0	benzyl alcohols; monomethoxybenzene; morpholines; pyridopyrimidine; tertiary amino compound	antineoplastic agent; mTOR inhibitor
14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene 14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene: has antineoplastic activity; also inhibits Fms-like tyrosine kinase-3; structure in first source	2.63	2	0
azd 7545 AZD 7545: an anilide tertiary carbinol; a pyruvate dehydrogenase kinase 2 inhibitor. AZD7545 : A sulfone that is benzene substituted by [4-(dimethylcarbamoyl)phenyl]sulfonyl, chloro and [(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino groups at positions 1, 3 and 4, respectively. It is a potent and non-ATP-competitive inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) with IC50 of 6.4 nM and exhibits glucose-lowering activity. Also inhibits PDHK1 at higher levels (IC50 = 36.8 nM).	2.08	1	0	benzamides; monochlorobenzenes; organofluorine compound; secondary carboxamide; sulfone; tertiary alcohol; tertiary carboxamide	EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor; hypoglycemic agent
nvp-bhg712 [no description available]	2.89	3	0	benzamides
azd5438 [no description available]	2.54	2	0	sulfonamide
nutlin-3b [no description available]	2.08	1	0	Nutlin; piperazinone	anticoronaviral agent
sphingosine kinase [no description available]	2.47	2	0
pf 04217903 [no description available]	3.25	5	0	quinolines
gdc 0941 pictrelisib : A sulfonamide composed of indazole, morpholine, and methylsulfonyl-substituted piperazine rings bound to a thienopyrimidine ring.	2.78	3	0	indazoles; morpholines; piperazines; sulfonamide; thienopyrimidine	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
sm 164 SM 164: a bivalent Smac mimetic with antineoplastic activity; structure in first source	2.08	1	0	benzenes; organic heterobicyclic compound; secondary carboxamide; triazoles	antineoplastic agent; apoptosis inducer; radiosensitizing agent
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-1,3-dihydroindol-2-one [no description available]	2.89	3	0	aromatic ketone
sapogenins Sapogenins: The aglucon moiety of a saponin molecule. It may be triterpenoid or steroid, usually spirostan, in nature.	2.17	1	0
icotinib [no description available]	3.61	2	0
ph 797804 PH 797804: an NSAID; structure in first source. PH 797804 : A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine.	3.25	5	0	aromatic ether; benzamides; organobromine compound; organofluorine compound; pyridone	anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
pha 408 PHA 408: an IKK-2 antagonist; structure in first source	2.08	1	0
gsk 1016790a GSK1016790A : A tertiary carboxamide that is piperazine in which one of the amino groups has undergone condensation with the carboxy group of N-[(2,4-dichlorophenyl)sulfonyl]-L-serine, while the other has undergone condensation with the carboxy group of N-(1-benzothiophen-2-ylcarbonyl)-L-leucine. It is a cell-permeable, potent and selective agonist of the TRPV4 (transient receptor potential vanilloid 4) channel.	2.08	1	0	1-benzothiophenes; aromatic primary alcohol; dichlorobenzene; N-acylpiperazine; sulfonamide; tertiary carboxamide	TRPV4 agonist
kx-01 [no description available]	2.15	1	0
mesna Mesna: A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.	3.23	1	0	organosulfonic acid
sodium lactate Sodium Lactate: The sodium salt of racemic or inactive lactic acid. It is a hygroscopic agent used intravenously as a systemic and urinary alkalizer.. sodium lactate : An organic sodium salt having lactate as the counterion.	3.23	1	0	lactate salt; organic sodium salt	food acidity regulator; food preservative
sodium iothalamate [no description available]	3.23	1	0
raltegravir potassium Raltegravir Potassium: A pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.	2.04	1	0
ro13-9904 Ceftriaxone: A broad-spectrum cephalosporin antibiotic and cefotaxime derivative with a very long half-life and high penetrability to meninges, eyes and inner ears.. ceftriaxone : A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups.	2.31	1	0
olaparib [no description available]	2.08	1	0	cyclopropanes; monofluorobenzenes; N-acylpiperazine; phthalazines	antineoplastic agent; apoptosis inducer; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
srt1720 [no description available]	3.07	4	0
plx 4720 PLX 4720: a B-Raf(V600E) kinase inhibitor; structure in first source	2.8	3	0	aromatic ketone; difluorobenzene; organochlorine compound; pyrrolopyridine; sulfonamide	antineoplastic agent; B-Raf inhibitor
mk 5108 [no description available]	2.54	2	0	aromatic ether
cx 4945 [no description available]	4.18	4	0
cudc 101 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide: a histone deacetylase inhibitor; structure in first source	4.11	4	0
purfalcamine purfalcamine: a PfCDPK-1 inhibitor; structure in first source	2.89	3	0
arry-614 pexmetinib: inhibits both p38 mitogen-activated protein kinase and Tie2 protein	2.15	1	0
tak 593 TAK 593: structure in first source	2.15	1	0
mln 8237 MLN 8237: an aurora kinase A inhibitor	3.02	4	0	benzazepine
lde225 sonidegib: specific Smoothened/Smo antagonist. sonidegib : A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma.	2.51	2	0	aminopyridine; aromatic ether; benzamides; biphenyls; morpholines; organofluorine compound; tertiary amino compound	antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist
gdc 0449 HhAntag691: inhibits the hedgehog pathway and ABC transporters; has antineoplastic activity	3.66	2	0	benzamides; monochlorobenzenes; pyridines; sulfone	antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist; teratogenic agent
sgx 523 [no description available]	2.78	3	0	aryl sulfide; biaryl; pyrazoles; quinolines; triazolopyridazine	c-Met tyrosine kinase inhibitor; nephrotoxic agent
bms 754807 BMS 754807: an IGR-1R kinase inhibitor; structure in first source	3.27	5	0	pyrazoles; pyridines; pyrrolidines; pyrrolotriazine	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
bms 777607 N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide: a Met kinase inhibitor; structure in first source	2.52	2	0	aromatic amide
sgi 1776 SGI 1776: a Pim kinase inhibitor; structure in first source	2.52	2	0	imidazoles
pci 32765 ibrutinib: a Btk protein inhibitor. ibrutinib : A member of the class of acrylamides that is (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies.	4.69	7	0	acrylamides; aromatic amine; aromatic ether; N-acylpiperidine; pyrazolopyrimidine; tertiary carboxamide	antineoplastic agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
ponatinib [no description available]	14.89	67	7	(trifluoromethyl)benzenes; acetylenic compound; benzamides; imidazopyridazine; N-methylpiperazine	antineoplastic agent; tyrosine kinase inhibitor
amg 900 N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine: a pan-aurora kinase inhibitor; structure in first source	2.52	2	0
mk-1775 adavosertib: a Wee1 kinase inhibitor; structure in first source	3.94	3	0	piperazines
AMG-208 [no description available]	2.15	1	0	aromatic ether; quinolines; triazolopyridazine	antineoplastic agent; c-Met tyrosine kinase inhibitor
bag956 BAG956: an imidazo[4,5-c]quinoline; dual PI3K/PDK-1 inhibitor, used in antileukemic therapies	2.08	1	0
quizartinib [no description available]	3.38	6	0	benzoimidazothiazole; isoxazoles; morpholines; phenylureas	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; necroptosis inhibitor
PP121 [no description available]	4.15	4	0	aromatic amine; cyclopentanes; pyrazolopyrimidine; pyrrolopyridine	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; tyrosine kinase inhibitor
at13148 [no description available]	2.15	1	0
N-[4-[3-[[[7-(hydroxyamino)-7-oxoheptyl]amino]-oxomethyl]-5-isoxazolyl]phenyl]carbamic acid tert-butyl ester CAY10603: a HDAC6 inhibitor	2.08	1	0	carbamate ester
tak 733 [no description available]	2.52	2	0
mk 2206 MK 2206: a protein kinase inhibitor and antineoplastic agent	4.13	4	0	organic heterotricyclic compound	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
navitoclax [no description available]	3.26	5	0	aryl sulfide; monochlorobenzenes; morpholines; N-sulfonylcarboxamide; organofluorine compound; piperazines; secondary amino compound; sulfone; tertiary amino compound	antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
sns 314 SNS 314: an aurora kinase inhibitor; structure in first source	2.52	2	0	ureas
jzl 184 JZL 184: inhibits monoacylglycerol lipase; structure in first source	2.08	1	0	benzodioxoles
gsk 650394 [no description available]	2.89	3	0	phenylpyridine
lucitanib E-3810: a multi-kinase inhibitor with antineoplastic activity; structure in first source. E-3810 : A hydrochloride salt obtained by reaction of 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide with one equivalent of hydrochloric acid. E-3810 is a dual VEGFR and FGFR inhibitor. E-3810 free base : A naphthalenecarboxamide obtained from formal condensation of the carboxy group of aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-1-naphthoic acid with methylamine.	2.15	1	0	aromatic ether; cyclopropanes; naphthalenecarboxamide; primary amino compound; quinolines	antineoplastic agent; fibroblast growth factor receptor antagonist; vascular endothelial growth factor receptor antagonist
pf-04691502 [no description available]	2.15	1	0
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene [no description available]	2.06	1	0	BODIPY compound
n-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide: a Janus kinase 1 and Janus kinase 2 inhibitor; structure in first source. momelotinib : A benzamide obtained by formal condensation of the carboxy group of 4-{2-[4-(morpholin-4-yl)anilino]pyrimidin-4-yl}benzoic acid with the primary amino group of aminoacetonitrile. It is an ATP-competitive JAK1/JAK2 inhibitor with IC50 of 11 nM and 18 nM, respectively. Used for the treatment of patients with intermediate- or high-risk myelofibrosis.	3.06	4	0	aminopyrimidine; benzamides; morpholines; nitrile; secondary amino compound; tertiary amino compound	anti-anaemic agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
dcc-2036 rebastinib: an inhibitor of Tie2 tyrosine kinase receptor and antineoplastic agent	4.65	7	0	organofluorine compound; phenylureas; pyrazoles; pyridinecarboxamide; quinolines	tyrosine kinase inhibitor
cetrorelix cetrorelix: LHRH antagonist. cetrorelix : A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-tyrosyl, N(5)-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.	3.23	1	0	oligopeptide	antineoplastic agent; GnRH antagonist
cabozantinib cabozantinib: a multikinase inhibitor. cabozantinib : A dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer.	4.65	7	0	aromatic ether; dicarboxylic acid diamide; organofluorine compound; quinolines	antineoplastic agent; tyrosine kinase inhibitor
defactinib [no description available]	2.15	1	0
ly2584702 [no description available]	2.15	1	0
N-(2,6-difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonyl-1-piperazinyl)-1-piperidinyl]anilino]-4-pyrimidinyl]-2-imidazo[1,2-a]pyridinyl]-2-methoxybenzamide [no description available]	2.08	1	0	benzamides
incb-018424 [no description available]	7.47	13	1	nitrile; pyrazoles; pyrrolopyrimidine	antineoplastic agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
poziotinib HM781-36B: antitumor irreversible Pan-HER inhibitor for treatment of gastric cancer	2.15	1	0	acrylamides; aromatic ether; dichlorobenzene; diether; monofluorobenzenes; N-acylpiperidine; quinazolines; secondary amino compound; substituted aniline	antineoplastic agent; apoptosis inducer; epidermal growth factor receptor antagonist
asp3026 ASP3026: an anaplastic lymphoma receptor tyrosine kinase inhibitor; structure in first source. ASP-3026 : A member of the class of diamino-1,3,5-triazines that is 1,3,5-triazine-2,4-diamine in which the amino groups at positions 2 and 4 are respectively carrying 2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl and 2-(propan-2-ylsulfonyl)phenyl substituents. It is a potent inhibitor of anaplastic lymphoma kinase (ALK), Ack and ROS1 activity (IC50 values are 3.5, 5.8 and 8.9 nM respectively) and exhibits anti-cancer properties.	2.54	2	0	aromatic amine; diamino-1,3,5-triazine; monomethoxybenzene; N-methylpiperazine; piperidines; secondary amino compound; sulfone	antimalarial; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
entrectinib entrectinib: inhibits TRK, ROS1, and ALK receptor tyrosine kinases; structure in first source. entrectinib : A member of the class of indazoles that is 1H-indazole substituted by [4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzoyl]amino and 3,5-difluorobenzyl groups at positions 3 and 5, respectively. It is a potent inhibitor of TRKA, TRKB, TRKC, ROS1, and ALK (IC50 values of 0.1 to 1.7 nM), and used for the treatment of NTRK, ROS1 and ALK gene fusion-positive solid tumours.	2.15	1	0	benzamides; difluorobenzene; indazoles; N-methylpiperazine; oxanes; secondary amino compound; secondary carboxamide	antibacterial agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
bix 01294 [no description available]	2.08	1	0	piperidines
pexidartinib pexidartinib: inhibits both CSF1R and c-kit receptor tyrosine kinase; structure in first source. pexidartinib : A pyrrolopyridine that is 5-chloro-1H-pyrrolo[2,3-b]pyridine which is substituted by a [6-({[6-(trifluoromethyl)pyridin-3-yl]methyl}amino)pyridin-3-yl]methyl group at position 3. It is a potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, KIT, and FLT3 (IC50 of 20 nM, 10 nM and 160 nM, respectively). Approved by the FDA for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT).	2.61	2	0	aminopyridine; organochlorine compound; organofluorine compound; pyrrolopyridine; secondary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
cobicistat [no description available]	3.51	1	0	1,3-thiazoles; carbamate ester; monocarboxylic acid amide; morpholines; ureas	P450 inhibitor
pf 3845 PF 3845: inhibits fatty acid amide hydrolase	2.08	1	0	piperidines
TAK-580 MLN 2480: brain-penetrant RAF dimer antagonist. TAK-580 : A 1,3-thiazolecarboxamide that is 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid in which the carboxy group undergoes formal condensation with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and in which the amino group undergoes formal condensation with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor which is currently in clinical development for the treatment of radiographically recurrent or progressive low-grade glioma in children and young adults.	3.27	5	0	1,3-thiazolecarboxamide; aminopyrimidine; chloropyridine; organofluorine compound; pyrimidinecarboxamide; secondary carboxamide	antineoplastic agent; apoptosis inducer; B-Raf inhibitor
gsk 2126458 omipalisib: inhibitor of mTOR protein. omipalisib : A member of the class of quinolines that is quinoline which is substituted by pyridazin-4-yl and 5-[(2,4-difluorobenzene-1-sulfonyl)amino]-6-methoxypyridin-3-yl groups at positions 4 and 6, respectively. It is a highly potent inhibitor of PI3K and mTOR developed by GlaxoSmithKline and was previously in human phase 1 clinical trials for the treatment of idiopathic pulmonary fibrosis and solid tumors.	2.52	2	0	aromatic ether; difluorobenzene; pyridazines; pyridines; quinolines; sulfonamide	anticoronaviral agent; antineoplastic agent; autophagy inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor; radiosensitizing agent
emd1214063 tepotinib: MET inhibitor	2.15	1	0
8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one [no description available]	2.89	3	0	chromones
gsk 1838705a [no description available]	2.06	1	0	organonitrogen compound; organooxygen compound
ixazomib ixazomib: a proteasome inhibitor with antineoplastic activity; MLN2238 is the biologically active form of MLN9708; structure in first source. ixazomib : A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma.	2.08	1	0	benzamides; boronic acids; dichlorobenzene; glycine derivative	antineoplastic agent; apoptosis inducer; drug metabolite; orphan drug; proteasome inhibitor
fit-039 FIT-039: CDK9 inhibitor; structure in first source	3.92	2	0
ldn 193189 LDN 193189: inhibits bone morphogenetic protein signaling	2.49	2	0	pyrimidines
pf 3758309 PF 3758309: a PAK4 p21-activated kinase inhibitor; structure in first source	3.1	4	0	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
jnj-40346527 JNJ-40346527: inhibits colony-stimulating factor-1 receptor kinase	2.31	1	0
gdc 0980 [no description available]	2.15	1	0
azd2014 vistusertib: potent and selective dual mTORC1 and mTORC2 inhibitor; structure in first source	2.88	3	0
(5-(2,4-bis((3s)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol: a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity; structure in first source	3.09	4	0	benzyl alcohols; morpholines; pyridopyrimidine; tertiary amino compound	antineoplastic agent; apoptosis inducer; mTOR inhibitor
plx4032 [no description available]	4.31	5	0	aromatic ketone; difluorobenzene; monochlorobenzenes; pyrrolopyridine; sulfonamide	antineoplastic agent; B-Raf inhibitor
(2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol [no description available]	2.08	1	0	biphenyls
gsk 1363089 GSK 1363089: a multikinase inhibitor that acts on Met, RON, Axl, and VEGFR; structure in first source	4.98	6	0	aromatic ether
arry-334543 ARRY-334543: an antagonist of ATP-binding cassette subfamily G member 2 (ABCG2); structure in first source	2.15	1	0
kin-193 [no description available]	2.52	2	0	pyridopyrimidine
mk 2461 [no description available]	2.54	2	0
5-(2-benzofuranyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine [no description available]	2.89	3	0	aryl sulfide; thienopyrimidine
5-(3-methylsulfonylphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine [no description available]	2.89	3	0	aryl sulfide; thienopyrimidine
5-bromo-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine [no description available]	2.89	3	0	aryl sulfide; thienopyrimidine
bay 869766 [no description available]	2.85	3	0
as 703026 [no description available]	2.15	1	0	pyridinecarboxamide
tak-441 TAK-441: structure in first source	3.41	1	0
baricitinib [no description available]	4.58	6	0	azetidines; nitrile; pyrazoles; pyrrolopyrimidine; sulfonamide	anti-inflammatory agent; antirheumatic drug; antiviral agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; immunosuppressive agent
4-[6-[4-(methoxycarbonylamino)phenyl]-4-(4-morpholinyl)-1-pyrazolo[3,4-d]pyrimidinyl]-1-piperidinecarboxylic acid methyl ester WYE-354: an mTOR inhibitor; structure in first source	2.08	1	0	carbamate ester
6-(1,3-benzodioxol-5-yl)-N-methyl-N-(thiophen-2-ylmethyl)-4-quinazolinamine [no description available]	2.89	3	0	quinazolines
piperidines Piperidines: A family of hexahydropyridines.	6.09	11	0
6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone ML-265: a small molecule activator of PKM2	3.07	4	0	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
interleukin-8 Interleukin-8: A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.	4.21	3	1
N-[(5-bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide [no description available]	2.89	3	0	hydroxyquinoline
p505-15 [no description available]	2.89	3	0
dabrafenib [no description available]	2.15	1	0	1,3-thiazoles; aminopyrimidine; organofluorine compound; sulfonamide	anticoronaviral agent; antineoplastic agent; B-Raf inhibitor
mrt67307 MRT67307: IKK (IκB(inhibitor of NF-κB (nuclear factor κB)) kinase) family inhibitor; structure in first source	2.89	3	0	aromatic amine
pki 587 gedatolisib: inhibits both phosphatidylinositol 3-kinase and mTOR; structure in first source	2.15	1	0
3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]aniline [no description available]	2.08	1	0	benzenes; sulfonamide
cp 466722 [no description available]	2.08	1	0	quinazolines
4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide: a protein kinase inhibitor; structure in first source	2.41	1	0
CAY10626 [no description available]	2.08	1	0	ureas
n-(3-fluoro-4-((1-methyl-6-(1h-pyrazol-4-yl)-1h-indazol-5 yl)oxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide merestinib: in phase I clinical trials (2013); structure in first source	2.15	1	0
N-[3-[[5-chloro-2-[4-(4-methyl-1-piperazinyl)anilino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide [no description available]	2.89	3	0	piperazines
thiopental sodium [no description available]	2.08	1	0	organochlorine compound; piperazines; pyrimidines	antineoplastic agent; tyrosine kinase inhibitor
pf 3644022 [no description available]	3.25	1	0
ribociclib ribociclib: inhibits both CDK4 and CDK6	3.1	4	0
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone [no description available]	2.89	3	0	aromatic ketone; thienopyrimidine
abt-450 paritaprevir: inhibits HCV NS3 protease. paritaprevir : An azamacrocycle which is used which is in combination with dasabuvir sodium hydrate, ombitasvir and ritonavir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver.	2.31	1	0
mk-8033 1-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo(4,5)cyclohepta(1,2-b)pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide: inhibits both Ron and c-Met kinases; structure in first source	2.54	2	0
3-(6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenol 3-(6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenol: inhibits ALK2 protein; structure in first source	2.1	1	0
pha 793887 [no description available]	3.25	5	0	piperidinecarboxamide
ly2784544 [no description available]	2.41	1	0	pyridazines
gsk 2334470 GSK 2334470: a PDK1 inhibitor; structure in first source	2.21	1	0	indazoles
sb 1518 [no description available]	2.63	2	0
abemaciclib [no description available]	3.73	2	0
mk-8776 [no description available]	2.15	1	0
nvp-bsk805 [no description available]	2.49	2	0
ml228 probe ML228 probe: structure in first source. ML228 : A member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway.	2.89	3	0	1,2,4-triazines; biphenyls; pyridines; secondary amino compound	hypoxia-inducible factor pathway activator
afuresertib [no description available]	2.15	1	0	amphetamines
xmd 8-92 XMD8-92 : A dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a [2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino substituent. It is an inhibitor of the BMK1 kinase pathway.	2.08	1	0	pyrimidobenzodiazepine	protein kinase inhibitor
hh-gv678 flumatinib: an antineoplastic agent and tyrosine kinase inhibitor	3.78	2	0
pf-03882845 [no description available]	2.89	3	0
bms 708163 BMS 708163: structure in first source	2.13	1	0	oxadiazole; ring assembly
gsk 1070916 GSK 1070916: an antineoplastic agent with aurora B/C kinase inhibitory activity	2.54	2	0	pyrazoles; ring assembly
jq1 compound [no description available]	4.37	5	0	carboxylic ester; organochlorine compound; tert-butyl ester; thienotriazolodiazepine	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; bromodomain-containing protein 4 inhibitor; cardioprotective agent; ferroptosis inducer
jnj38877605 [no description available]	2.52	2	0	quinolines
N-[3-(1,3-benzothiazol-2-yl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-2-yl]acetamide [no description available]	2.08	1	0	benzothiazoles
dinaciclib [no description available]	4.75	4	0	pyrazolopyrimidine
pf-04620110 PF-04620110: a DGAT1 inhibitor; structure in first source	2.89	3	0
gsk525762a molibresib: mimicks acetylated histones; structure in first source	2.89	3	0	benzodiazepine
calcipotriene calcipotriene: a topical dermatologic for the treatment of moderate plaque psoriasis; structure in first source. calcipotriol hydrate : A hydrate that is the monohydrate form of calcipotriol. It is used in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.	2.31	1	0	hydrate	antipsoriatic
gilteritinib gilteritinib: an FLT3/AXL protein tyrosine kinase inhibitor. gilteritinib : A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation.	2.63	2	0	aromatic amine; monomethoxybenzene; N-methylpiperazine; oxanes; piperidines; primary carboxamide; pyrazines; secondary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
alectinib [no description available]	3.73	2	0	aromatic ketone; morpholines; nitrile; organic heterotetracyclic compound; piperidines	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
glpg0634 [no description available]	2.63	2	0
birinapant birinapant: a Smac mimetic with antineoplastic activity	2.21	1	0	dipeptide
torin 1 torin 1 : A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.	3.07	4	0	N-acylpiperazine; N-arylpiperazine; organofluorine compound; pyridoquinoline; quinolines	antineoplastic agent; mTOR inhibitor
abt-199 venetoclax: A BCL-2 inhibitor with antineoplastic activity that is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA associated with chromosome 17p deletion; structure in first source.. venetoclax : A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion.	2.89	3	0	aromatic ether; C-nitro compound; monochlorobenzenes; N-alkylpiperazine; N-arylpiperazine; N-sulfonylcarboxamide; oxanes; pyrrolopyridine	antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
ly2940680 [no description available]	3.65	2	0
1-[4-fluoro-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea [no description available]	3.07	4	0	ureas
N-(4-methyl-2-pyridinyl)-4-[3-(trifluoromethyl)anilino]-1-piperidinecarbothioamide [no description available]	2.89	3	0	(trifluoromethyl)benzenes
ro 4929097 [no description available]	2.08	1	0	dibenzoazepine; dicarboxylic acid diamide; lactam; organofluorine compound	EC 3.4.23.46 (memapsin 2) inhibitor
LSM-6732 [no description available]	3.25	1	0	organonitrogen heterocyclic compound; organosulfur heterocyclic compound; tert-butyl ester
ncgc00242364 NCGC00242364: structure in first source	2.89	3	0	quinazolines
gsk4112 GSK4112: a Rev-erbalpha agonist; structure in first source	2.08	1	0
ipi-145 [no description available]	2.15	1	0	isoquinolines
delgocitinib delgocitinib: a Janus kinase inhibitor. delgocitinib : A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a (3S,4R)-1-(cyanoacetyl)-3-methyl-1,6-diazaspiro[3.4]octan-6-yl group at position 4. It is a pan-Janus kinase (JAK) inhibitor and is approved for treatment of atopic dermatitis (AD) in Japan.	2.41	1	0	azaspiro compound; N-acylazetidine; nitrile; pyrrolopyrimidine; tertiary amino compound; tertiary carboxamide	anti-inflammatory drug; antipsoriatic; antiseborrheic; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
encorafenib encorafenib: a BRAF inhibitor	2.15	1	0
bms-911543 N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo(4,5-d)pyrrolo(2,3b)pyridine-7-carboxamide: has antineoplastic activity; structure in first source	2.15	1	0
gsk2141795 GSK2141795: an Akt inhibitor with antineoplastic activity; structure in first source	2.15	1	0
methylcellulose Methylcellulose: Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.	2.11	1	0
torin 2 torin 2 : A member of the class of pyridoquinolines that is benzo[h][1,6]naphthyridin-2-one carrying additional 3-(trifluoromethyl)phenyl and 6-aminopyridin-3-yl substituents at positions 1 and 9 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.	2.08	1	0	aminopyridine; organofluorine compound; primary amino compound; pyridoquinoline	antineoplastic agent; mTOR inhibitor
pf-4708671 [no description available]	2.08	1	0
gsk1210151a GSK1210151A: inhibitor of the BET family of proteins; structure in first source	4.23	4	0	imidazoquinoline
azd8186 [no description available]	2.15	1	0
hs-173 [no description available]	2.89	3	0
sr1664 [no description available]	2.89	3	0	indolecarboxamide
4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-n-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide 4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide: inhibits phosphopantetheinyl transferase; structure in first source	2.89	3	0
natriuretic peptide, brain Natriuretic Peptide, Brain: A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.	2.07	1	0	polypeptide
incb039110 INCB039110: a JAK1 inhibitor; structure in first source	2.41	1	0
N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide [no description available]	2.83	3	0	benzamides; N-acylpiperidine
N-[4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide [no description available]	2.59	2	0	aminoquinoline
2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide : A member of the class of quinazolines that is quinazoline substituted by {3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}amino and 3-(2-methoxyacetamido)prop-1-en-1-yl groups at positions 4 and 6, respectively.	2.08	1	0	aromatic ether; methylpyridines; olefinic compound; quinazolines; secondary amino compound; secondary carboxamide; toluenes
belinostat [no description available]	2.08	1	0	olefinic compound
pf 4800567 PF-4800567 : A pyrazolopyrimidine that is 1H-pyrazolo[3,4-d]pyrimidin-4-amine which is substituted at positions 1 and 3 by tetrahydro-2H-pyran-4-yl and (m-chlorophenoxy)methyl groups, respectively. It is a selective inhibitor of the epsilon isoform of casein kinase 1 (CK1epsilon).	3.25	1	0	aromatic ether; monochlorobenzenes; oxanes; pyrazolopyrimidine	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
cudc-907 [no description available]	2.89	3	0
ascorbic acid Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.. L-ascorbic acid : The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.. L-ascorbate : The L-enantiomer of ascorbate and conjugate base of L-ascorbic acid, arising from selective deprotonation of the 3-hydroxy group. Required for a range of essential metabolic reactions in all animals and plants.. vitamin C : Any member of a group of vitamers that belong to the chemical structural class called butenolides that exhibit biological activity against vitamin C deficiency in animals. The vitamers include L-ascorbic acid and its salt, ionized and oxidized forms.	3.23	1	0	ascorbic acid; vitamin C	coenzyme; cofactor; flour treatment agent; food antioxidant; food colour retention agent; geroprotector; plant metabolite; skin lightening agent
raltegravir [no description available]	3.61	2	0	1,2,4-oxadiazole; dicarboxylic acid amide; hydroxypyrimidine; monofluorobenzenes; pyrimidone; secondary carboxamide	antiviral drug; HIV-1 integrase inhibitor
novobiocin Novobiocin: An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189). novobiocin : A coumarin-derived antibiotic obtained from Streptomyces niveus.	3.51	1	0	carbamate ester; ether; hexoside; hydroxycoumarin; monocarboxylic acid amide; monosaccharide derivative; phenols	antibacterial agent; antimicrobial agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; Escherichia coli metabolite; hepatoprotective agent
tetracycline Tetracycline: A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.. tetracycline : A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.	3.23	1	0
oxytetracycline, anhydrous Oxytetracycline: A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES RIMOSUS and used in a wide variety of clinical conditions.. oxytetracycline : A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.	3.23	1	0
minocycline Minocycline: A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.. minocycline : A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5.	3.23	1	0
methacycline Methacycline: A broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.. methacycline : A tetracycline that is the 6-methylene analogue of oxytetracycline, obtained by formal dehydration at position 6.	2.21	1	0
piroxicam [no description available]	3.23	1	0	benzothiazine; monocarboxylic acid amide; pyridines	analgesic; antirheumatic drug; cyclooxygenase 1 inhibitor; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-steroidal anti-inflammatory drug
mobic Meloxicam: A benzothiazine and thiazole derivative that acts as a NSAID and cyclooxygenase-2 (COX-2) inhibitor. It is used in the treatment of RHEUMATOID ARTHRITIS; OSTEOARTHRITIS; and ANKYLOSING SPONDYLITIS.. meloxicam : A benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis.	3.23	1	0	1,3-thiazoles; benzothiazine; monocarboxylic acid amide	analgesic; antirheumatic drug; cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate: RN & structure given in first source	2.08	1	0	carboxylic acid; pyrroline
warfarin Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.	5.29	3	1	benzenes; hydroxycoumarin; methyl ketone
demeclocycline Demeclocycline: A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.. demeclocycline : Tetracycline which lacks the methyl substituent at position 7 and in which the hydrogen para- to the phenolic hydroxy group is substituted by chlorine. Like tetracycline, it is an antibiotic, but being excreted more slowly, effective blood levels are maintained for longer. It is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.	3.23	1	0
tipranavir tipranavir: inhibits HIV-1 protease. tipranavir : A pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor.	3.23	1	0	sulfonamide	antiviral drug; HIV protease inhibitor
methacycline monohydrochloride [no description available]	2.59	2	0
2-[[[4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]-oxomethyl]amino]acetic acid [no description available]	2.89	3	0	quinolines
tigecycline [no description available]	3.23	1	0
a 769662 [no description available]	2.08	1	0	biphenyls
agi-5198 AGI-5198: inhibits isocitrate dehydrogenase 1; structure in first source	2.89	3	0
byl719 [no description available]	2.55	2	0	proline derivative
ent-crizotinib ent-crizotinib : A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that is the (S)-enantiomer of crizotinib.	3.25	1	0	3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
transforming growth factor beta Transforming Growth Factor beta: A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.	2.52	2	0
cep-32496 agerafenib: inhibitor of RAF family kinases; structure in first source	3.27	5	0
pf-5274857 1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one: a potent and selective Smoothened antagonist that penetrates the blood-brain barrier; structure in first source	3.41	1	0
epz004777 [no description available]	2.89	3	0	N-glycosyl compound
3-[[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid [no description available]	2.89	3	0	organonitrogen heterocyclic compound
LimKi 3 LIMKi3: LIMK inhibitor. LimKi 3 : A member of the class of pyrazoles that is 1-(2,6-dichlorophenyl)-1H-pyrazole which is substituted by a difluoromethyl group at position 3 and by a 2-(isobutyrylamino)-1,3-thiazol-5-yl group at position 5. It is a a potent cell-permeable inhibitor of LIM kinase 1 and 2.	2.08	1	0	1,3-thiazoles; dichlorobenzene; organofluorine compound; pyrazoles; secondary carboxamide	LIM kinase inhibitor
1-[4-amino-7-[3-(2-methoxyethylamino)propyl]-5-(4-methylphenyl)-6-pyrrolo[2,3-d]pyrimidinyl]-2-fluoroethanone [no description available]	2.08	1	0	pyrroles
rociletinib rociletinib: inhibits epidermal growth factor receptor tyrosine kinase activity; structure in first source	3.73	2	0
entecavir [no description available]	2.89	3	0	benzamides; N-acylpiperidine
epz-5676 [no description available]	2.21	1	0	5'-deoxyribonucleoside
2-[5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-4-methoxy-2-pyrrolylidene]indole [no description available]	2.08	1	0	dipyrrins
ceritinib ceritinib: an anaplastic lymphoma kinase inhibitor. ceritinib : A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonyl)phenyl substituents. Used for the treatment of ALK-positive metastatic non-small cell lung cancer.	2.58	2	0	aminopyrimidine; aromatic ether; organochlorine compound; piperidines; secondary amino compound; sulfone	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-2-propenamide [no description available]	2.08	1	0	tryptamines
3-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]-6-(phenylmethylene)piperazine-2,5-dione [no description available]	2.08	1	0	pyrazines
gsk837149a GSK837149A: structure in first source	2.08	1	0
N-[4-(3-chloro-4-fluoroanilino)-7-[[(3S)-3-oxolanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide [no description available]	2.08	1	0	quinazolines
N-[4-(3-chloro-4-fluoroanilino)-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide [no description available]	2.08	1	0	quinazolines
wnt-c59 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide: a PORCN acyltransferase inhibitor; structure in first source	2.08	1	0
5-[1-(2-hydroxyethyl)-3-pyridin-4-yl-4-pyrazolyl]-2,3-dihydroinden-1-one oxime [no description available]	2.08	1	0	indanes
azd1208 [no description available]	2.15	1	0
gkt137831 setanaxib: NOX4/NOX1 inhibitor; a pyrazolopyridine dione derivative	2.89	3	0
vx-509 [no description available]	3.1	4	0
vx-970 berzosertib: an ATR kinase inhibitor	4.45	5	0	sulfonamide
gs-9973 [no description available]	2.89	3	0
rki-1447 RKI-1447: an antineoplastic agent that inhibits ROCK1 and ROCK2; structure in first source	3.41	1	0
ldn-212854 [no description available]	2.1	1	0
amg 925 AMG-925 : An organic heterotricyclic compound that is 9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidine which is substituted by a [6-(hydroxyacetyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]nitrilo group at position 2 and by a trans-4-methylcyclohexyl group at position 9. It is a FLT3 and CDK4 dual kinase inhibitor that has antineoplastic activity. Currently under clinical investigation in patients with relapsed or refractory acute myeloid leukemia (AML).	2.89	3	0
debio 1347 CH5183284: a fibroblast growth factor receptor antagonist; structure in first source	2.15	1	0
gne-618 GNE-618: inhibits nicotinamide phosphoribosyl transferase; structure in first source	2.89	3	0
g007-lk G007-LK: potent and specific small-molecule tankyrase inhibitor; structure in first source	2.89	3	0
volitinib [no description available]	3.1	4	0
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester: a breast cancer resistance protein (BCRP) inhibitor; structure in first source	2.49	2	0
ML355 ML355: 12-Lipoxygenase inhibitor. ML355 : A sulfonamide resulting from the formal condensation of the amino group of 2-aminobenzothiazole with the sulfo group of 4-[(2-hydroxy-3-methoxybenzyl)amino]benzenesulfonic acid. It is an inhibitor of 12-lipoxygenase, being developed by Veralox Therapeutics for the treatment of heparin-induced thrombocytopenia and thrombosis.	2.89	3	0	benzothiazoles; monomethoxybenzene; phenols; secondary amino compound; substituted aniline; sulfonamide	EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; platelet aggregation inhibitor
acp-196 acalabrutinib: inhibits Bruton’s tyrosine kinase; has antineoplastic activity. acalabrutinib : A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy.	2.89	3	0	aromatic amine; benzamides; imidazopyrazine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; ynone	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
gsk343 GSK343: an EZH2 methyltransferase inhibitor. GSK343 : A member of the class of indazoles that is 1-isopropyl-1H-indazole-4-carboxamide in which the nitrogen of the carboxamide group is substituted by a (6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl group and in which the indazole ring is substituted at position 6 by a 2-(4-methylpiperazin-1-yl)pyridin-4-yl group. A highly potent and selective EZH2 inhibitor (IC50 = 4 nM).	2.89	3	0	aminopyridine; indazoles; N-alkylpiperazine; N-arylpiperazine; pyridone; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
agi-6780 AGI-6780: inhibits isocitrate dehydrogenases 1 and 2; structure in first source	2.89	3	0
khs101 KHS101: a small molecule accelerates neuronal differentiation in the adult rat	2.89	3	0
osimertinib osimertinib: an EGFR tyrosine kinase inhibitor. osimertinib : A member of the class of aminopyrimidines that is 4-(1-methylindol-3-yl)pyrimidin-2-amine in which one of the amino hydrogens is replaced by a 2-methoxy-4-[2-(dimethylamino)ethyl](methyl)amino-5-acrylamidophenyl group. Used (as the mesylate salt) for treatment of EGFR T790M mutation positive non-small cell lung cancer.	2.15	1	0	acrylamides; aminopyrimidine; biaryl; indoles; monomethoxybenzene; secondary amino compound; secondary carboxamide; substituted aniline; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
cb-839 [no description available]	2.89	3	0
gsk-j4 GSK-J4: a JMJD3 inhibitor; structure in first source	2.89	3	0	organonitrogen heterocyclic compound
pf-06424439 PF-06424439: an inhibitor of diacylglycerol acyltransferase 2; structure in first source	2.89	3	0
etp-46464 ETP-46464: inhibits ATM and Rad3-related kinase; structure in first source	2.89	3	0
DDR1-IN-1 DDR1-IN-1 : A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzoic acid with the amino group of 5-(5-amino-2-methylphenoxy)-1,3-dihydro-2H-indol-2-one. It is a potent inhibitor of discoidin domain receptor tyrosine kinase 1 and 2 (DDR1/2) with IC50 = 105 nM and 413 nM, respectively.	3.6	2	0	(trifluoromethyl)benzenes; aromatic ether; benzamides; N-alkylpiperazine; oxindoles; secondary carboxamide	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
imetelstat [no description available]	4.05	2	0
onc201 TIC10 compound: a TRAIL-dependent antitumor agent; structure in first source	2.89	3	0
kai407 KAI407: an antimalarial; structure in first source	2.89	3	0
fertinex [no description available]	3.23	1	0
ldc4297 LDC4297: a CDK7 inhibitor with antineoplastic activity; structure in first source. LDC4297 : A pyrazolotriazine that is pyrazolo[1,5-a][1,3,5]triazine substituted by a piperidin-3-yloxy group, [2-(1H-pyrazol-1-yl)benzyl]nitrilo group and an isopropyl group at positions 2, 4 and 8 respectively. It is a potent and selective CDK7 inhibitor and exhibits antiviral activity.	2.41	1	0	aromatic ether; piperidines; pyrazoles; pyrazolotriazine; secondary amino compound	antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
6,7-dimethoxy-2-(pyrrolidin-1-yl)-n-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine: a SETD8 inhibitor; structure in first source	2.89	3	0
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone: an interleukin-1beta converting enzyme (ICE)-like protease inhibitor	2.52	2	0
nitrophenols Nitrophenols: PHENOLS carrying nitro group substituents.	2.52	2	0
enasidenib [no description available]	2.89	3	0	1,3,5-triazines; aminopyridine; aromatic amine; organofluorine compound; secondary amino compound; tertiary alcohol	antineoplastic agent; EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
oicr-9429 OICR-9429: antineoplastic; structure in first source	2.89	3	0
lly-507 LLY-507: inhibits methyltransferase SMYD2; structure in first source. LLY-507 : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}[biphenyl]-3-carboxylic acid with the amino group of 3-(pyrrolidin-1-yl)propan-1-amine. It is a potent and selective inhibitor of SMYD2 and inhibits the ability of SMYD2 to methylate p53. It serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.	2.89	3	0
epoetin alfa Epoetin Alfa: A recombinant glycosylated form of erythropoietin which stimulates the differentiation and proliferation of erythroid precursors. It is used for the treatment of ANEMIA associated with CHRONIC RENAL FAILURE in dialysis and predialysis patients.	2.06	1	0
oblimersen oblimersen: targets the Bcl-2 oncogene good efficacy with low toxicity tumour regressions	2.03	1	0
cyclosporine Cyclosporine: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).	3.07	4	0
protopanaxatriol protopanaxatriol: triterpenoid sapogenin of ginsenosides from leaves of Panax ginseng; acid hydrolysis leads to panaxatriol. protopanaxatriol : A tetracyclic triterpenoid sapogenin (isolated from ginseng and notoginseng) that is that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions and in which a double bond has been introduced at the 24-25 position.	2.17	1	0
at 9283 [no description available]	4.58	6	0
otssp167 OTS167: inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity	2.15	1	0
akt-i-1,2 compound Akt-I-1,2 compound: an aminopeptidase P inhibitor; structure in first source	3.15	1	0
entecavir entecavir (anhydrous) : Guanine substituted at the 9 position by a 4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl group. A synthetic analogue of 2'-deoxyguanosine, it is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. Entecavir is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. It is used for the treatment of chronic hepatitis B.	3.23	1	0	2-aminopurines; oxopurine; primary alcohol; secondary alcohol	antiviral drug; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
chir 258 [no description available]	4.14	4	0
acyclovir Acyclovir: A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.. acyclovir : An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.	3.23	1	0	2-aminopurines; oxopurine	antimetabolite; antiviral drug
osi 027 OSI 027: inhibits both mTORC1 and mTORC2; structure in first source	2.81	3	0
hypoxanthine [no description available]	2.89	3	0	nucleobase analogue; oxopurine; purine nucleobase	fundamental metabolite
sapropterin sapropterin: RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases. (6R)-5,6,7,8-tetrahydrobiopterin : A 5,6,7,8-tetrahydrobiopterin in which the stereocentre at position 6 has R-configuration.. sapropterin : A tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3H)-one in which a hydrogen at position 6 is substituted by a 1,2-dihydroxypropyl group (6R,1'R,2'S-enantiomer).	2.04	1	0	5,6,7,8-tetrahydrobiopterin	coenzyme; cofactor; diagnostic agent; human metabolite
folic acid folcysteine: used to promote fertility in chickens. vitamin B9 : Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin.	3.66	2	0	folic acids; N-acyl-amino acid	human metabolite; mouse metabolite; nutrient
rifampin Rifampin: A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)	6.03	4	1	cyclic ketal; hydrazone; N-iminopiperazine; N-methylpiperazine; rifamycins; semisynthetic derivative; zwitterion	angiogenesis inhibitor; antiamoebic agent; antineoplastic agent; antitubercular agent; DNA synthesis inhibitor; EC 2.7.7.6 (RNA polymerase) inhibitor; Escherichia coli metabolite; geroprotector; leprostatic drug; neuroprotective agent; pregnane X receptor agonist; protein synthesis inhibitor
clozapine Clozapine: A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.. clozapine : A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia.	4.35	5	0	benzodiazepine; N-arylpiperazine; N-methylpiperazine; organochlorine compound	adrenergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; GABA antagonist; histamine antagonist; muscarinic antagonist; second generation antipsychotic; serotonergic antagonist; xenobiotic
dacarbazine (E)-dacarbazine : A dacarbazine in which the N=N double bond adopts a trans-configuration.	5.94	2	1	dacarbazine
didanosine Didanosine: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.. didanosine : A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen. An antiviral drug, it is used as a medication to treat HIV/AIDS.	3.23	1	0	purine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor; geroprotector; HIV-1 reverse transcriptase inhibitor
ganciclovir [no description available]	3.23	1	0	2-aminopurines; oxopurine	antiinfective agent; antiviral drug
valacyclovir Valacyclovir: A prodrug of acyclovir that is used in the treatment of HERPES ZOSTER and HERPES SIMPLEX VIRUS INFECTION of the skin and mucous membranes, including GENITAL HERPES.	3.23	1	0	L-valyl ester	antiviral drug
sildenafil sildenafil : A pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position.	3.23	1	0	piperazines; pyrazolopyrimidine; sulfonamide	EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor; vasodilator agent
olanzapine Olanzapine: A benzodiazepine derivative that binds SEROTONIN RECEPTORS; MUSCARINIC RECEPTORS; HISTAMINE H1 RECEPTORS; ADRENERGIC ALPHA-1 RECEPTORS; and DOPAMINE RECEPTORS. It is an antipsychotic agent used in the treatment of SCHIZOPHRENIA; BIPOLAR DISORDER; and MAJOR DEPRESSIVE DISORDER; it may also reduce nausea and vomiting in patients undergoing chemotherapy.. olanzapine : A benzodiazepine that is 10H-thieno[2,3-b][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4.	3.23	1	0	benzodiazepine; N-arylpiperazine; N-methylpiperazine	antiemetic; dopaminergic antagonist; histamine antagonist; muscarinic antagonist; second generation antipsychotic; serotonergic antagonist; serotonin uptake inhibitor
vardenafil vardenafil : The sulfonamide resulting from formal condensation of the sulfo group of 4-ethoxy-3-(5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one-2-yl)benzenesulfonic acid and the secondary amino group of 4-ethylpiperazine.	3.23	1	0	imidazotriazine; N-alkylpiperazine; N-sulfonylpiperazine	EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent
allopurinol Allopurinol: A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.. allopurinol : A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.	3.23	1	0	nucleobase analogue; organic heterobicyclic compound	antimetabolite; EC 1.17.3.2 (xanthine oxidase) inhibitor; gout suppressant; radical scavenger
hli 373 [no description available]	2.08	1	0
citrovorum factor [no description available]	3.23	1	0	tetrahydrofolic acid
leucovorin 5-formyltetrahydrofolic acid : A formyltetrahydrofolic acid in which the formyl group is located at position 5.	3.23	1	0	formyltetrahydrofolic acid	Escherichia coli metabolite; mouse metabolite
rifapentine rifapentine: cyclopentyl derivative of rifampicin	3.23	1	0	N-alkylpiperazine; N-iminopiperazine; rifamycins	antitubercular agent; leprostatic drug
bl 4162a anagrelide: imidazoquinazoline derivative which lowers platelet count probably by inhibiting thrombopoiesis and reduces platelet aggregation; used for thrombocythemia; structure in first source. anagrelide : A 1,5-dihydroimidazo[2,1-]quinazoline having an oxo substituent at the 2-position and chloro substituents at the 6- and 7-positions.	3.64	2	0	imidazoquinazoline	anticoagulant; antifibrinolytic drug; cardiovascular drug; platelet aggregation inhibitor
tegaserod tegaserod: a nonbenzamide 5-hydroxytryptamine(4) agonist; used in treatment of irritable bowel syndrome; marketing suspended 2007 in US due to higher incidence of MI, stroke, and unstable angina; structure given in first source	3.23	1	0	carboxamidine; guanidines; hydrazines; indoles	gastrointestinal drug; serotonergic agonist
pemetrexed pemetrexed disodium : An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).	3.93	3	0	N-acyl-L-glutamic acid; pyrrolopyrimidine	antimetabolite; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; EC 2.1.1.45 (thymidylate synthase) inhibitor; EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
1-hydroxyphenazine 1-hydroxyphenazine: a virulence factor of Pseudomonas aeruginosa. 1-hydroxyphenazine : A phenazine carrying a hydroxy substituent at the 1-position.	2.89	3	0	phenazines
sildenafil citrate Sildenafil Citrate: A PHOSPHODIESTERASE TYPE-5 INHIBITOR; VASODILATOR AGENT and UROLOGICAL AGENT that is used in the treatment of ERECTILE DYSFUNCTION and PRIMARY PULMONARY HYPERTENSION.. sildenafil citrate : The citrate salt of sildenafil.	3.59	2	0	citrate salt	EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor; vasodilator agent
valganciclovir Valganciclovir: A ganciclovir prodrug and antiviral agent that is used to treat CYTOMEGALOVIRUS RETINITIS in patients with AIDS, and for the prevention of CYTOMEGALOVIRUS INFECTIONS in organ transplant recipients who have received an organ from a CMV-positive donor.. valganciclovir : The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.	3.23	1	0	L-valyl ester; purines	antiviral drug; prodrug
aprepitant Aprepitant: A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.. aprepitant : A morpholine-based antiemetic, which is or the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.	3.61	2	0	(trifluoromethyl)benzenes; cyclic acetal; morpholines; triazoles	antidepressant; antiemetic; neurokinin-1 receptor antagonist; peripheral nervous system drug; substance P receptor antagonist
fosaprepitant fosaprepitant: a pro-drug form of aprepitant. fosaprepitant : A morpholine derivative that is the (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl ether of (3-{[(2R,3S)-3-(4-fluorophenyl)-2-hydroxymorpholin-4-yl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid.	3.23	1	0	(trifluoromethyl)benzenes; cyclic acetal; morpholines; phosphoramide; triazoles	antiemetic; neurokinin-1 receptor antagonist; prodrug
vardenafil dihydrochloride Vardenafil Dihydrochloride: A piperazine derivative, PHOSPHODIESTERASE 5 INHIBITOR and VASODILATOR AGENT that is used as a UROLOGICAL AGENT in the treatment of ERECTILE DYSFUNCTION.	3.19	1	0
rifabutin [no description available]	3.23	1	0
xav939 XAV939: selectively inhibits beta-catenin-mediated transcription; structure in first source. XAV939 : A thiopyranopyrimidine in which a 7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine skeleton is substituted at C-4 by a hydroxy group and at C-2 by a para-(trifluoromethyl)phenyl group.	2.08	1	0	(trifluoromethyl)benzenes; thiopyranopyrimidine	tankyrase inhibitor
ag-879 AG-879: structure given in first source	3.92	2	0
2-carboxyarabinitol 1-phosphate [no description available]	2.08	1	0
hesperadin [no description available]	2.41	1	0
ro 24-7429 Ro 24-7429: blocks the action of the HIV tat protein; an analog of Ro 5-3335; Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6395-9	2.89	3	0	benzodiazepine
nintedanib nintedanib : A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer.	4.75	8	0
amg531 [no description available]	4.13	2	0
debromohymenialdisine [no description available]	2.15	1	0
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide [no description available]	2.89	3	0	catechols; hydrazide; hydrazone; naphthols	EC 3.6.5.5 (dynamin GTPase) inhibitor
ver 52296 luminespib : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(2,4-dihydroxy-5-isopropylphenyl)-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxylic acid with the amino group of ethylamine.	3.07	4	0	aromatic amide; isoxazoles; monocarboxylic acid amide; morpholines; resorcinols	angiogenesis inhibitor; antineoplastic agent; Hsp90 inhibitor
levomefolate calcium levomefolate calcium: an ingredient in Contraceptives, Oral, Combined. levomefolate calcium : An organic calcium salt of (6S)-5-methyltetrahydrofolic acid.	3.23	1	0	organic calcium salt	antidepressant
sb-590885 N-{5-[2-{4-[2-(dimethylamino)ethoxy]phenyl}-4-(pyridin-4-yl)-1H-imidazol-5-yl]-2,3-dihydro-1H-inden-1-ylidene}hydroxylamine : A ketoxime that is the oxime of indan-1-one in which the hydrogen at position 5 has been replaced by an imidazol-5-yl group which has itself been substituted at positions 2 and 4 by p-[2-(dimethylamino)ethoxy]phenyl and pyridin-4-yl groups, respectively.	2.08	1	0	aromatic ether; imidazoles; ketoxime; pyridines; tertiary amino compound
rvx 208 apabetalone: a bromodomain and extra-terminal domain protein (BET) inhibitor; prevents interactions between BET proteins and acetyl-lysine residues on histone tails to modify epigenetic regulation	2.89	3	0
bmn 673 talazoparib: inhibits both PARP1 and PARP2; structure in first source	2.89	3	0
pf-477736 PF 00477736: a Chk1 inhibitor; structure in first source. PF-00477736 : A diazepinoindole that is 8-amino-4,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one which is substituted at position 2 by a 1-methylpyrazol-4-yl group and in which the amino group at position 8 has undergone condensation with the carboxy group of (2R)-2-cyclohexylglycine to give the corresponding carboxamide. It is an inhibitor of checkpoint kinase 1 (Chk 1).	2.08	1	0
bay 80-6946 copanlisib: an antineoplastic agent with PI3K inhibitory activity; structure in first source. copanlisib : An imidazoquinazoline that is 2,3-dihydroimidazo[1,2-c]quinazoline substituted by (2-aminopyrimidine-5-carbonyl)amino, methoxy, and 3-(morpholin-4-yl)propoxy groups at positions 5, 7 and 8, respectively. It is a intravenous pan-class I PI3K inhibitor used for the treatment of relapsed follicular lymphoma in patients who have received at least 2 prior systemic therapies.	2.54	2	0
pp242 torkinib : A member of the class of pyrazolopyrimidines that is 1H-pyrazolo[3,4-d]pyrimidine substituted by isopropyl, 5-hydroxyindol-2-yl and amino groups at positions 1, 3 and 4 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.	3.6	2	0	aromatic amine; biaryl; hydroxyindoles; phenols; primary amino compound; pyrazolopyrimidine	antineoplastic agent; mTOR inhibitor
fenobam fenobam: in USAN fenobam refers to monohydrate	2.08	1	0	ureas

Condition	Indicated	Relationship Strength	Studies	Trials
Granulocytic Leukemia, Chronic [description not available]	0	25.54	878	163
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.	1	27.54	878	163
Leucocythaemia [description not available]	0	6.02	18	0
Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)	1	8.02	18	0
Angiogenesis, Pathologic [description not available]	0	2.51	2	0
Torsade de Pointes [description not available]	0	2.08	1	0
Benign Neoplasms [description not available]	0	8.08	19	0
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	1	11.95	38	0
Fibrodysplasia Ossificans Progressiva [description not available]	0	2.1	1	0
Myositis Ossificans A disease characterized by bony deposits or the ossification of muscle tissue.	0	2.1	1	0
Innate Inflammatory Response [description not available]	0	7.77	13	1
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	0	7.77	13	1
Experimental Neoplasms [description not available]	0	3.22	5	0
Acute Liver Injury, Drug-Induced [description not available]	0	5.7	12	0
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.	0	5.7	12	0
Cancer of Lung [description not available]	0	2.83	3	0
Acute Myelogenous Leukemia [description not available]	0	5.73	11	0
Lung Neoplasms Tumors or cancer of the LUNG.	0	2.83	3	0
Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.	1	7.73	11	0
Degenerative Diseases, Central Nervous System [description not available]	0	4.67	3	0
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.	0	4.67	3	0
Blast Phase [description not available]	0	12.73	32	9
Blast Crisis An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.	0	12.73	32	9
Hematologic Malignancies [description not available]	0	5.68	6	1
Benign Neoplasms, Brain [description not available]	0	5.12	3	1
Astrocytoma, Grade IV [description not available]	0	2.58	2	0
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.	0	5.12	3	1
Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.	0	2.58	2	0
Hematologic Neoplasms Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.	0	5.68	6	1
Congenital Zika Syndrome [description not available]	0	2.25	1	0
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	0	9.16	48	0
Zika Virus Infection A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.	0	2.25	1	0
2019 Novel Coronavirus Disease [description not available]	0	3.04	3	0
Viral Diseases [description not available]	0	3.74	2	0
Virus Diseases A general term for diseases caused by viruses.	0	3.74	2	0
Benign Cerebellar Neoplasms [description not available]	0	3.23	1	0
Arachnoidal Cerebellar Sarcoma, Circumscribed [description not available]	0	3.57	2	0
Medulloblastoma A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)	0	3.57	2	0
Idiopathic Parkinson Disease [description not available]	0	11.3	25	13
Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)	1	13.3	25	13
Breast Cancer [description not available]	0	4.17	5	0
Breast Neoplasms Tumors or cancer of the human BREAST.	1	6.17	5	0
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)	0	2.63	2	0
Pleural Effusion Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.	0	4.53	8	0
Disease Exacerbation [description not available]	0	14.47	49	15
Acute Lymphoid Leukemia [description not available]	0	15.15	56	18
Precursor Cell Lymphoblastic Leukemia-Lymphoma A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.	1	17.15	56	18
Malignant Melanoma [description not available]	0	9.14	16	4
Cancer of Skin [description not available]	0	8.41	14	2
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)	1	14.95	48	12
Skin Neoplasms Tumors or cancer of the SKIN.	0	8.41	14	2
Leukemia, Pre-B-Cell [description not available]	0	4.25	3	1
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.	0	4.25	3	1
Granulocytic Leukemia, Chronic, Stable Phase [description not available]	0	17.76	107	37
Ph 1 Chromosome [description not available]	0	13.31	45	8
Autosomal Dominant Cerebellar Ataxia, Type II [description not available]	0	2.41	1	0
Spinocerebellar Ataxias A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)	0	2.41	1	0
Recrudescence [description not available]	0	13.58	32	14
Exanthem [description not available]	0	7.49	5	2
Lichen Ruber Planus [description not available]	0	2.82	2	0
Exanthema Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.	0	7.49	5	2
Lichen Planus An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.	0	2.82	2	0
Genetic Predisposition [description not available]	0	6.58	10	1
Diffuse Parenchymal Lung Disease [description not available]	0	3.61	8	0
Idiopathic Interstitial Pneumonia [description not available]	0	2.41	1	0
Cough A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.	0	2.41	1	0
Lung Diseases, Interstitial A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.	0	3.61	8	0
Smoking Cessation Discontinuing the habit of SMOKING.	0	3.33	1	0
Leukocytopenia [description not available]	0	2.41	1	0
Thrombopenia [description not available]	0	3.47	2	0
Leukopenia A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).	0	2.41	1	0
Thrombocytopenia A subnormal level of BLOOD PLATELETS.	0	3.47	2	0
Cutaneous T-Cell Lymphoma [description not available]	0	2.41	1	0
Lymphoma, T-Cell, Cutaneous A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders.	0	2.41	1	0
B-Cell Leukemia [description not available]	0	2.82	2	0
Arrhythmia [description not available]	0	2.41	1	0
Arrhythmias, Cardiac Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.	0	2.41	1	0
Aortic Stenosis [description not available]	0	2.41	1	0
Calcification, Pathologic [description not available]	0	2.41	1	0
Aortic Valve Stenosis A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.	0	2.41	1	0
Calcinosis Pathologic deposition of calcium salts in tissues.	0	2.41	1	0
Cognitive Decline [description not available]	0	2.41	1	0
Cognitive Dysfunction Diminished or impaired mental and/or intellectual function.	0	2.41	1	0
Fibrous Histiocytoma of Tendon Sheath [description not available]	0	5.02	2	1
Diffuse Tenosynovial Giant Cell Tumor [description not available]	0	7.32	4	2
Local Neoplasm Recurrence [description not available]	0	9.05	12	3
Giant Cell Tumor of Tendon Sheath A tumor arising in the SYNOVIAL MEMBRANE; SYNOVIAL BURSA; or TENDON sheath. It is characterized by OSTEOCLAST-like GIANT CELLS; FOAM CELLS; pigmented HEMOSIDERIN-laden MACROPHAGES and inflammatory infiltrate. It is classified either as diffuse or localized tenosynovitis.	0	5.02	2	1
Synovitis, Pigmented Villonodular Diffuse outgrowth arising from the SYNOVIAL MEMBRANE; SYNOVIAL BURSA; or TENDON sheath around the joint cavity, with extension to surrounding soft tissue. It is characterized by pigmented HEMOSIDERIN-containing MACROPHAGES; FOAM CELLS; and multinucleated GIANT CELLS. It usually occurs in the hands and feet, and around large joints, such as in the ankle and knee joints.	1	9.32	4	2
Chronic Illness [description not available]	0	10.06	19	8
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).	0	10.06	19	8
Clinically Isolated CNS Demyelinating Syndrome [description not available]	0	2.69	2	0
Demyelinating Diseases Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.	0	2.69	2	0
Dermatitis Medicamentosa [description not available]	0	5.35	12	0
Itching [description not available]	0	2.21	1	0
Asthenia Clinical sign or symptom manifested as debility, or lack or loss of strength and energy.	0	3.46	2	0
Pruritus An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.	0	2.21	1	0
Cirrhosis, Liver [description not available]	0	3.71	9	0
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.	0	3.71	9	0
Drug Withdrawal Symptoms [description not available]	0	3.89	2	1
Substance Withdrawal Syndrome Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.	0	3.89	2	1
Aura [description not available]	0	2.21	1	0
Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)	0	2.21	1	0
Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.	0	15.8	56	41
Acute Kidney Failure [description not available]	0	3.02	4	0
Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.	0	3.02	4	0
Bleeding [description not available]	0	3.23	5	0
Hemorrhage Bleeding or escape of blood from a vessel.	0	3.23	5	0
Thromboembolism Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.	0	2.25	1	0
Carcinoma, Anaplastic [description not available]	0	2.25	1	0
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.	0	2.25	1	0
Arterial Brain Diseases [description not available]	0	2.25	1	0
Hyperglycemia, Postprandial Abnormally high BLOOD GLUCOSE level after a meal.	0	2.52	2	0
Hyperglycemia Abnormally high BLOOD GLUCOSE level.	0	2.52	2	0
Hypertriglyceridemia A condition of elevated levels of TRIGLYCERIDES in the blood.	0	2.21	1	0
Cardiovascular Stroke [description not available]	0	2.83	3	0
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).	0	2.83	3	0
Cirrhosis [description not available]	0	4.62	9	0
Graft-Versus-Host Disease [description not available]	0	8.4	12	4
Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.	0	4.62	9	0
Graft vs Host Disease The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.	1	10.4	12	4
Hepatocellular Carcinoma [description not available]	0	2.81	3	0
Cancer of Liver [description not available]	0	4.52	8	0
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	0	2.81	3	0
Liver Neoplasms Tumors or cancer of the LIVER.	0	4.52	8	0
Diabetes Mellitus, Adult-Onset [description not available]	0	3.36	6	0
Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.	0	3.36	6	0
Multiple System Atrophy Syndrome [description not available]	0	2.59	2	0
a-Synucleinopathies [description not available]	0	2.25	1	0
Multiple System Atrophy A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)	0	2.59	2	0
Gastrointestinal Stromal Neoplasm [description not available]	0	12.94	45	5
Arteriosclerosis, Coronary [description not available]	0	4.4	7	0
Cancer of Gastrointestinal Tract [description not available]	0	7.87	18	1
Coronary Artery Disease Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.	0	4.4	7	0
Gastrointestinal Stromal Tumors All tumors in the GASTROINTESTINAL TRACT arising from mesenchymal cells (MESODERM) except those of smooth muscle cells (LEIOMYOMA) or Schwann cells (SCHWANNOMA).	1	14.94	45	5
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	0	5.7	9	0
Acute Confusional Senile Dementia [description not available]	0	5.29	10	0
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)	1	7.29	10	0
Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.	0	4.2	3	0
Blood Diseases [description not available]	0	7.96	7	1
Dermatoses [description not available]	0	2.25	1	0
Hematologic Diseases Disorders of the blood and blood forming tissues.	0	7.96	7	1
Skin Diseases Diseases involving the DERMIS or EPIDERMIS.	0	2.25	1	0
American Trypanosomiasis [description not available]	0	2.25	1	0
Chagas Disease Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.	0	2.25	1	0
Abnormalities, Multiple Congenital abnormalities that affect more than one organ or body structure.	0	4.25	5	0
Acantholytic Dyskeratotic Epidermal Nevi [description not available]	0	3.14	4	0
Chromosomal Translocation [description not available]	0	5.5	10	0
HPV Infection [description not available]	0	2.25	1	0
Carcinoma, Squamous Cell of Head and Neck [description not available]	0	2.25	1	0
Cancer of Head [description not available]	0	5.37	4	1
Squamous Cell Carcinoma of Head and Neck The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer.	0	2.25	1	0
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)	0	5.37	4	1
Papillomavirus Infections Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.	0	2.25	1	0
Pityriasis Rubra Pilaris A chronic skin disease characterized by small follicular papules, disseminated reddish-brown scaly patches, and often, palmoplantar hyperkeratosis. The papules are about the size of a pin and topped by a horny plug.	0	2.25	1	0
Sterility, Female [description not available]	0	2.25	1	0
Infertility, Female Diminished or absent ability of a female to achieve conception.	0	2.25	1	0
Adenocarcinoma, Basal Cell [description not available]	0	3.95	4	0
Animal Mammary Carcinoma [description not available]	0	2.25	1	0
Experimental Mammary Neoplasms [description not available]	0	2.25	1	0
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	0	3.95	4	0
Cortical Lewy Body Disease [description not available]	0	9.93	11	9
Lewy Body Disease A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)	0	9.93	11	9
Myeloproliferative Disorders Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.	0	7.71	9	1
Carcinoma, Epidermoid [description not available]	0	2.84	3	0
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	0	2.84	3	0
Kahler Disease [description not available]	0	3.71	3	0
Multiple Myeloma A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.	0	3.71	3	0
Bilirubinemia [description not available]	0	4.98	8	1
Chemical and Drug Induced Liver Injury, Chronic Liver disease lasting six months or more, caused by an adverse effect of a drug or chemical. The adverse effect may be caused by drugs, drug metabolites, chemicals from the environment, or an idiosyncratic response.	0	2.25	1	0
Left Ventricular Dysfunction [description not available]	0	2.52	2	0
Cardiac Toxicity [description not available]	0	3.99	4	0
Ventricular Dysfunction, Left A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.	0	2.52	2	0
Cardiotoxicity Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.	0	3.99	4	0
Thromboembolism, Venous [description not available]	0	2.25	1	0
Venous Thromboembolism Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.	0	2.25	1	0
Alopecia Cicatrisata [description not available]	0	2.89	3	0
Alopecia Absence of hair from areas where it is normally present.	0	2.89	3	0
Dyslipidemia [description not available]	0	3.08	4	0
Arterial Obstructive Diseases [description not available]	0	4.41	7	0
Arterial Occlusive Diseases Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.	0	4.41	7	0
Dyslipidemias Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.	0	3.08	4	0
Cardiac Rupture, Traumatic [description not available]	0	2.31	1	0
Vascular Diseases Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.	0	4.56	8	0
Familial Nonmedullary Thyroid Cancer [description not available]	0	2.41	1	0
Cancer of the Thyroid [description not available]	0	3.51	2	0
Thyroid Neoplasms Tumors or cancer of the THYROID GLAND.	0	3.51	2	0
Acanthocytosis with Neurologic Disorder [description not available]	0	2.31	1	0
Cerebral Infarction, Middle Cerebral Artery [description not available]	0	3.23	1	0
Acute Ischemic Stroke [description not available]	0	3.23	1	0
Cerebral Arteriosclerosis [description not available]	0	3.23	1	0
Ischemic Stroke Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.	0	3.23	1	0
Intracranial Arteriosclerosis Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.	0	3.23	1	0
Infarction, Middle Cerebral Artery NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.	0	3.23	1	0
Elephantiasis Neuromatosis [description not available]	0	2.57	2	0
Neurofibroma, Plexiform A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestation of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131(5):678-82)	0	2.57	2	0
Stunted Growth [description not available]	0	4.62	1	1
Growth Disorders Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.	0	4.62	1	1
Pulmonary Hypertension [description not available]	0	5.6	11	0
Hypertension, Pulmonary Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.	1	7.6	11	0
Cold Panniculitis [description not available]	0	2.15	1	0
Metastase [description not available]	0	7.19	7	3
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.	0	7.19	7	3
Tricuspid Incompetence [description not available]	0	2.15	1	0
Carotid Artery Narrowing [description not available]	0	2.87	3	0
Carotid Stenosis Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)	0	2.87	3	0
Granulocytic Leukemia [description not available]	0	4.8	2	1
Acute Disease Disease having a short and relatively severe course.	0	4.76	6	1
Leukemia, Myeloid Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.	1	6.8	2	1
Adiadochokinesis [description not available]	0	3.06	1	0
Cerebellar Ataxia Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)	1	5.06	1	0
Pleuropericarditis Inflammation of both the PERICARDIUM and the PLEURA.	0	2.15	1	0
Pericarditis Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.	0	2.15	1	0
Polyps Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.	0	3.06	1	0
Gastric Diseases [description not available]	0	3.06	1	0
Neurilemoma [description not available]	0	2.5	2	0
Acoustic Neurinoma, Bilateral [description not available]	0	2.79	3	0
Peripheral Nerve Neoplasms [description not available]	0	2.15	1	0
Neurilemmoma A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)	1	4.5	2	0
Peripheral Nervous System Neoplasms Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)	0	2.15	1	0
Neurofibromatosis 2 An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.	0	2.79	3	0
Koch's Disease [description not available]	0	2.15	1	0
Tuberculosis Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.	0	2.15	1	0
Prediabetes [description not available]	0	2.15	1	0
Prediabetic State The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2).	0	2.15	1	0
Atherogenesis [description not available]	0	2.83	3	0
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.	0	2.83	3	0
Peripheral Arterial Diseases [description not available]	0	5.35	12	1
Peripheral Arterial Disease Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.	0	5.35	12	1
Anasarca [description not available]	0	3.68	3	0
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.	0	3.68	3	0
Hematochezia The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.	0	2.51	2	0
Colicky Pain [description not available]	0	2.52	2	0
Jejunal Diseases Pathological development in the JEJUNUM region of the SMALL INTESTINE.	0	2.15	1	0
Hematoma A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue.	0	2.15	1	0
Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.	0	2.51	2	0
Abdominal Pain Sensation of discomfort, distress, or agony in the abdominal region.	0	2.52	2	0
Peripheral Nerve Diseases [description not available]	0	2.58	2	0
Polyneuropathy, Acquired [description not available]	0	2.17	1	0
Peripheral Nervous System Diseases Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.	0	2.58	2	0
Polyneuropathies Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.	0	2.17	1	0
Hyperlipemia [description not available]	0	2.57	2	0
Hyperlipidemias Conditions with excess LIPIDS in the blood.	0	2.57	2	0
Amentia [description not available]	0	9.93	11	9
Dementia An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.	0	9.93	11	9
Brill-Symmers Disease [description not available]	0	2.17	1	0
Lymphoma, Follicular Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES.	0	2.17	1	0
Arthritis, Spinal [description not available]	0	5.76	2	1
Central Nervous System Neoplasm [description not available]	0	2.8	3	0
Neoplasms, Bone Marrow [description not available]	0	2.17	1	0
Central Nervous System Neoplasms Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.	0	2.8	3	0
Bone Marrow Neoplasms Neoplasms located in the bone marrow. They are differentiated from neoplasms composed of bone marrow cells, such as MULTIPLE MYELOMA. Most bone marrow neoplasms are metastatic.	0	2.17	1	0
Embryopathies [description not available]	0	3.09	1	0
Allodynia [description not available]	0	2.17	1	0
Colorectal Cancer [description not available]	0	3.46	2	0
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.	0	3.46	2	0
Invasiveness, Neoplasm [description not available]	0	4.26	6	0
Lassitude [description not available]	0	3.71	3	0
Fatigue The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.	0	3.71	3	0
Sclerosis A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.	0	3.56	1	1
Cardiac Diseases [description not available]	0	3.19	5	0
Heart Diseases Pathological conditions involving the HEART including its structural and functional abnormalities.	0	3.19	5	0
Alveolar Echinococcosis, Hepatic [description not available]	0	2.17	1	0
Brain Vascular Disorders [description not available]	0	3.71	3	0
Cerebrovascular Disorders A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.	0	3.71	3	0
Libman-Sacks Disease [description not available]	0	2.61	2	0
Lupus Erythematosus, Systemic A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.	0	2.61	2	0
Chronic Kidney Diseases [description not available]	0	2.54	2	0
Heart Disease, Ischemic [description not available]	0	2.17	1	0
Myocardial Ischemia A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).	0	2.17	1	0
Renal Insufficiency, Chronic Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)	0	2.54	2	0
Nerve Degeneration Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.	0	2.17	1	0
Incontinentia Pigmenti Achromians [description not available]	0	3.44	2	0
Cytomegalic Inclusion Disease [description not available]	0	4.48	1	1
Cytomegalovirus Infections Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.	0	4.48	1	1
Ache [description not available]	0	4.4	4	1
Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.	0	4.4	4	1
Impaired Glucose Tolerance [description not available]	0	2.17	1	0
Compensatory Hyperinsulinemia A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.	0	2.17	1	0
Insulin Sensitivity [description not available]	0	3.04	4	0
Hyperinsulinism A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.	0	2.17	1	0
Insulin Resistance Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.	0	3.04	4	0
Glucose Intolerance A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.	0	2.17	1	0
Chordoma A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)	1	5.89	2	1
Muscle Pain [description not available]	0	2.17	1	0
Amaurosis Fugax Transient complete or partial monocular blindness due to retinal ischemia. This may be caused by emboli from the CAROTID ARTERY (usually in association with CAROTID STENOSIS) and other locations that enter the central RETINAL ARTERY. (From Adams et al., Principles of Neurology, 6th ed, p245)	0	2.17	1	0
Myalgia Painful sensation in the muscles.	0	2.17	1	0
Infection [description not available]	0	2.17	1	0
Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.	0	2.17	1	0
Complications, Hematologic Pregnancy [description not available]	0	2.17	1	0
Complications, Neoplastic Pregnancy [description not available]	0	4.39	4	0
Weight Gain Increase in BODY WEIGHT over existing weight.	0	2.25	1	0
Orthopedic Disorders [description not available]	0	3.12	1	0
Musculoskeletal Diseases Diseases of the muscles and their associated ligaments and other connective tissue and of the bones and cartilage viewed collectively.	0	3.12	1	0
Respiratory Tract Diseases Diseases involving the RESPIRATORY SYSTEM.	0	3.12	1	0
B16 Melanoma [description not available]	0	2.53	2	0
Adenoma, Prostatic [description not available]	0	2.21	1	0
Cancer of Prostate [description not available]	0	2.55	2	0
Prostatic Hyperplasia Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.	0	2.21	1	0
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	0	2.55	2	0
Intestinal Perforation Opening or penetration through the wall of the INTESTINES.	0	2.21	1	0
Intestinal Obstruction Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.	0	2.21	1	0
Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	0	2.21	1	0
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.	0	2.21	1	0
Coronary Artery Stenosis [description not available]	0	2.21	1	0
Coronary Stenosis Narrowing or constriction of a coronary artery.	0	2.21	1	0
Carcinoma, Non-Small Cell Lung [description not available]	0	2.21	1	0
Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.	0	2.21	1	0
Apoplexy [description not available]	0	2.53	2	0
Auricular Fibrillation [description not available]	0	2.21	1	0
Atrial Fibrillation Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.	0	2.21	1	0
Stroke A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)	0	2.53	2	0
Non-ST-Elevation Myocardial Infarction [description not available]	0	3.12	1	0
Cerebrovascular Moyamoya Disease [description not available]	0	3.12	1	0
Non-ST Elevated Myocardial Infarction A myocardial infarction that does not produce elevations in the ST segments of the ELECTROCARDIOGRAM. ST segment elevation of the ECG is often used in determining the treatment protocol (see also ST Elevation Myocardial Infarction).	0	3.12	1	0
Blood Clot [description not available]	0	13.97	40	37
Thrombosis Formation and development of a thrombus or blood clot in the blood vessel.	0	13.97	40	37
Leukemia, Lymphocytic, Chronic, T Cell [description not available]	0	2.21	1	0
Leukemia, Prolymphocytic, T-Cell A lymphoid leukemia characterized by a profound LYMPHOCYTOSIS with or without LYMPHADENOPATHY, hepatosplenomegaly, frequently rapid progression, and short survival. It was formerly called T-cell chronic lymphocytic leukemia.	0	2.21	1	0
Neointima The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.	0	2.21	1	0
Diathesis [description not available]	0	2.21	1	0
Angor Pectoris [description not available]	0	2.21	1	0
Cerebral Ischemia [description not available]	0	2.54	2	0
Diseases, Peripheral Vascular [description not available]	0	2.81	3	0
Angina Pectoris The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.	0	2.21	1	0
Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.	0	2.54	2	0
Peripheral Vascular Diseases Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.	0	2.81	3	0
Nephrotic Syndrome A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.	0	2.21	1	0
Anterior Choroidal Artery Infarction [description not available]	0	2.21	1	0
Cerebral Infarction The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).	0	2.21	1	0
Drug-Induced Cochlear Toxicity [description not available]	0	2.25	1	0
Ototoxicity Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.	0	2.25	1	0
Afibrinogenemia, Congenital [description not available]	0	2.21	1	0
Thrombocytopathy [description not available]	0	2.21	1	0
Afibrinogenemia A deficiency or absence of FIBRINOGEN in the blood.	0	2.21	1	0
Blood Platelet Disorders Disorders caused by abnormalities in platelet count or function.	0	2.21	1	0
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	0	2.54	2	0
Alloxan Diabetes [description not available]	0	2.55	2	0
Chylopericardium [description not available]	0	3.42	2	0
Pericardial Effusion Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.	0	3.42	2	0
Constitutional Liver Dysfunction [description not available]	0	2.21	1	0
Cancer of Intestines [description not available]	0	2.08	1	0
Sarcoma, Epithelioid [description not available]	0	2.48	2	0
Intestinal Neoplasms Tumors or cancer of the INTESTINES.	0	2.08	1	0
Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.	1	4.48	2	0
Chronic Hepatitis B [description not available]	0	2.08	1	0
Hepatitis B, Chronic INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.	0	2.08	1	0
Genome Instability [description not available]	0	2.48	2	0
Barrett Epithelium [description not available]	0	2.1	1	0
Cancer of Esophagus [description not available]	0	2.1	1	0
Barrett Esophagus A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.	0	2.1	1	0
Esophageal Neoplasms Tumors or cancer of the ESOPHAGUS.	0	2.1	1	0
Sycosis [description not available]	0	2.1	1	0
Folliculitis Inflammation of follicles, primarily hair follicles.	0	2.1	1	0
Tumour Lysis Syndrome [description not available]	0	2.46	2	0
Tumor Lysis Syndrome A syndrome resulting from cytotoxic therapy, occurring generally in aggressive, rapidly proliferating lymphoproliferative disorders. It is characterized by combinations of hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia.	0	2.46	2	0
Autosomal Dominant Juvenile Parkinson Disease [description not available]	0	6.37	9	0
Parkinsonian Disorders A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.	0	6.37	9	0
Cancer, Second Primary [description not available]	0	3.73	3	0
Palmoplantaris Pustulosis [description not available]	0	2.08	1	0
Psoriasis A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.	0	2.08	1	0
Cognition Disorders Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.	0	3	1	0
Lung Injury, Acute [description not available]	0	4.15	3	0
Neutropenia A decrease in the number of NEUTROPHILS found in the blood.	0	5.06	3	1
Acute Lung Injury A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).	0	4.15	3	0
Abnormalities, Autosome [description not available]	0	4.59	9	0
Atypical Chronic Myeloid Leukemia [description not available]	0	2.08	1	0
Sclerosis, Systemic [description not available]	0	4.84	7	0
Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.	0	4.84	7	0
Gastritis Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.	0	3.47	1	1
Heritable Pulmonary Arterial Hypertension [description not available]	0	3.4	2	0
Familial Primary Pulmonary Hypertension Familial or idiopathic hypertension in the PULMONARY CIRCULATION which is not secondary to other disease.	0	3.4	2	0
Blood Pressure, High [description not available]	0	4.39	4	0
Disease, Pulmonary [description not available]	0	3.42	2	0
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	0	4.39	4	0
Lung Diseases Pathological processes involving any part of the LUNG.	0	3.42	2	0
Endocarditis, Loeffler [description not available]	0	7.35	9	1
Hypereosinophilic Syndrome A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.	0	7.35	9	1
Weight Reduction [description not available]	0	2.08	1	0
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.	0	2.08	1	0
Weight Loss Decrease in existing BODY WEIGHT.	0	2.08	1	0
Cafe-au-Lait Spots with Pulmonic Stenosis [description not available]	0	2.1	1	0
Neoplasms, Nerve Sheath [description not available]	0	2.1	1	0
Neurofibromatosis 1 An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).	0	2.1	1	0
Nerve Sheath Neoplasms Neoplasms which arise from nerve sheaths formed by SCHWANN CELLS in the PERIPHERAL NERVOUS SYSTEM or by OLIGODENDROCYTES in the CENTRAL NERVOUS SYSTEM. Malignant peripheral nerve sheath tumors, NEUROFIBROMA, and NEURILEMMOMA are relatively common tumors in this category.	0	2.1	1	0
Pemphigus Foliaceus [description not available]	0	2.47	2	0
Pemphigus Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.	0	2.47	2	0
Leukemia, Myelogenous, Aggressive Phase [description not available]	0	10.35	12	7
Minimal Disease, Residual [description not available]	0	10.09	12	10
Tuberculosis, Drug-Resistant [description not available]	0	3.04	1	0
Agnogenic Myeloid Metaplasia [description not available]	0	3.04	1	0
Adverse Drug Event [description not available]	0	7.42	5	2
Eosinophilia, Tropical [description not available]	0	4.15	3	0
Mast Cell Activation Disease [description not available]	0	3.9	2	0
Erythremia [description not available]	0	3.39	2	0
Alveolitis, Fibrosing [description not available]	0	5.01	5	0
Alastrim [description not available]	0	3.04	1	0
Hemorrhagic Thrombocythemia [description not available]	0	3.04	1	0
Eosinophilia Abnormal increase of EOSINOPHILS in the blood, tissues or organs.	0	4.15	3	0
Mastocytosis A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).	0	3.9	2	0
Polycythemia Vera A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.	0	3.39	2	0
Pulmonary Fibrosis A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.	0	5.01	5	0
Smallpox An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed)	0	3.04	1	0
Thrombocythemia, Essential A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.	0	3.04	1	0
Tuberculosis, Multidrug-Resistant Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.	0	3.04	1	0
Primary Myelofibrosis A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.	0	3.04	1	0
Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.	0	7.42	5	2
Drug-Induced Stevens Johnson Syndrome [description not available]	0	2.1	1	0
Stevens-Johnson Syndrome Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.	0	2.1	1	0
Cancer of Stomach [description not available]	0	3.7	3	0
Stomach Neoplasms Tumors or cancer of the STOMACH.	0	3.7	3	0
Acute Hypercapnic Respiratory Failure [description not available]	0	2.1	1	0
Respiratory Insufficiency Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)	0	2.1	1	0
Leukemia, Lymphoblastic, Acute, T Cell [description not available]	0	2.1	1	0
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.	0	2.1	1	0
Elevated Cholesterol [description not available]	0	2.1	1	0
Hypercholesterolemia A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.	0	2.1	1	0
Airway Remodeling The structural changes in the number, mass, size and/or composition of the airway tissues.	0	2.52	2	0
Asthma, Bronchial [description not available]	0	2.52	2	0
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	0	2.52	2	0
Remission, Spontaneous A spontaneous diminution or abatement of a disease over time, without formal treatment.	0	2.11	1	0
Bone Marrow Diseases Diseases involving the BONE MARROW.	0	2.49	2	0
Cancer of Ovary [description not available]	0	2.77	3	0
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.	0	2.77	3	0
Alveolar Proteinoses, Pulmonary [description not available]	0	2.1	1	0
Pulmonary Alveolar Proteinosis A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.	0	2.1	1	0
Eye Disorders [description not available]	0	2.1	1	0
Xanthoma [description not available]	0	2.52	2	0
Eye Diseases Diseases affecting the eye.	0	2.1	1	0
Coronary Heart Disease [description not available]	0	2.11	1	0
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.	0	2.11	1	0
Acute Promyelocytic Leukemia [description not available]	0	2.11	1	0
Leukemia, Promyelocytic, Acute An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.	0	2.11	1	0
Glial Cell Tumors [description not available]	0	2.11	1	0
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)	1	4.11	1	0
ER-Negative PR-Negative HER2-Negative Breast Cancer [description not available]	0	2.11	1	0
Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.	0	2.49	2	0
Triple Negative Breast Neoplasms Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.	0	2.11	1	0
Aggressive Systemic Mastocytosis A form of systemic mastocytosis in which patients have impaired organ functions due to multifocal infiltrates of pathological MAST CELLS in bone marrow, liver, spleen, gastrointestinal tract, or skeletal system. The cytomorphology shows a low to high grade.	0	6.77	8	1
Mastocytosis, Systemic A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.	0	6.77	8	1
Neoplasms, Squamous Cell Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements.	0	2.11	1	0
Muscle Disorders [description not available]	0	2.49	2	0
Muscular Diseases Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.	0	2.49	2	0
Antidiuretic Hormone, Inappropriate Secretion [description not available]	0	2.13	1	0
Hyponatremia Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)	0	2.13	1	0
Inappropriate ADH Syndrome A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.	0	2.13	1	0
Leg Ulcer Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.	0	2.53	2	0
Amyloid Deposits [description not available]	0	3.03	1	0
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.	0	3.4	2	0
Diffuse Cutaneous Systemic Sclerosis [description not available]	0	4.41	1	1
Bilateral Headache [description not available]	0	6.47	3	3
Anemia A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.	0	4.41	1	1
Headache The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.	0	6.47	3	3
Nausea An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.	0	4.8	2	1
Scleroderma, Diffuse A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability.	0	4.41	1	1
Adenoma, Basal Cell [description not available]	0	2.11	1	0
Cancer of Pituitary [description not available]	0	2.11	1	0
Adenoma A benign epithelial tumor with a glandular organization.	0	2.11	1	0
Pituitary Neoplasms Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.	0	2.11	1	0
Diabetic Glomerulosclerosis [description not available]	0	2.49	2	0
Diabetic Nephropathies KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.	0	2.49	2	0
Fibromatosis [description not available]	0	3.03	1	0
Angioma A vascular anomaly due to proliferation of blood or lymphatic vessels that forms a tumor-like mass. Vessels in the angioma may or may not be dilated.	0	3.03	1	0
Cancer of Pancreas [description not available]	0	3.03	1	0
Acute Edematous Pancreatitis [description not available]	0	3.92	4	0
Papilloma, Squamous Cell [description not available]	0	3.03	1	0
Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.	0	4.33	2	0
Fibroma A benign tumor of fibrous or fully developed connective tissue.	0	3.03	1	0
Hemangioma A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)	0	3.03	1	0
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	0	3.03	1	0
Pancreatitis INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.	0	3.92	4	0
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)	0	3.03	1	0
Facial Dermatoses Skin diseases involving the FACE.	0	2.13	1	0
Acneiform Eruptions Visible efflorescent lesions of the skin caused by acne or resembling acne. (Dorland, 28th ed, p18, 575)	0	2.13	1	0
Hyperhomocysteinemia Condition in which the plasma levels of homocysteine and related metabolites are elevated (	0	2.13	1	0
Enterocolitis Inflammation of the MUCOSA of both the SMALL INTESTINE and the LARGE INTESTINE. Etiology includes ISCHEMIA, infections, allergic, and immune responses.	0	2.11	1	0
Antral Vascular Ectasia [description not available]	0	2.13	1	0
Eyelid Diseases Diseases involving the EYELIDS.	0	2.13	1	0
Liver Dysfunction [description not available]	0	2.54	2	0
Kidney Diseases Pathological processes of the KIDNEY or its component tissues.	0	2.53	2	0
Liver Diseases Pathological processes of the LIVER.	0	2.54	2	0
Androgen-Independent Prostatic Cancer [description not available]	0	2.13	1	0
Prostatic Neoplasms, Castration-Resistant Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE.	0	2.13	1	0
Abnormalities, Drug-Induced Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.	0	3.04	1	0
Keratoderma Blennorrhagicum [description not available]	0	2.53	2	0
Keratosis Any horny growth such as a wart or callus.	0	2.53	2	0
Glucose Metabolic Disorder [description not available]	0	3.04	1	0
Diseases of Endocrine System [description not available]	0	3.04	1	0
Endocrine System Diseases Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.	0	3.04	1	0
Hypoascorbemia [description not available]	0	2.13	1	0
Scurvy An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs.	0	2.13	1	0
Kidney Failure A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.	0	2.48	2	0
Renal Insufficiency Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.	0	2.48	2	0
Cholangiocellular Carcinoma [description not available]	0	2.15	1	0
Bile Duct Cancer [description not available]	0	2.15	1	0
Bile Duct Neoplasms Tumors or cancer of the BILE DUCTS.	0	2.15	1	0
Cholangiocarcinoma A malignant tumor arising from the epithelium of the BILE DUCTS.	0	2.15	1	0
Pneumatosis Cystoides Intestinalis A condition characterized by the presence of multiple gas-filled cysts in the intestinal wall, the submucosa and/or subserosa of the INTESTINE. The majority of the cysts are found in the JEJUNUM and the ILEUM.	0	3.04	1	0
Pyrexia [description not available]	0	4.43	1	1
Diseases, Metabolic [description not available]	0	4.79	2	1
Fever An abnormal elevation of body temperature, usually as a result of a pathologic process.	0	4.43	1	1
Metabolic Diseases Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)	0	4.79	2	1
Atheroma [description not available]	0	2.15	1	0
Dysembryoma [description not available]	0	2.13	1	0
Teratoma A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)	0	2.13	1	0
Rhabdoid Tumor A rare but highly lethal childhood tumor found almost exclusively in infants. Histopathologically, it resembles RHABDOMYOSARCOMA but the tumor cells are not of myogenic origin. Although it arises primarily in the kidney, it may be found in other parts of the body. The rhabdoid cytomorphology is believed to be the expression of a very primitive malignant cell. (From Holland et al., Cancer Medicine, 3d ed, p2210)	0	2.13	1	0
Chronic Lung Injury [description not available]	0	2.15	1	0
Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).	0	2.15	1	0
Hepatic Failure [description not available]	0	2.17	1	0
Liver Failure Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)	0	2.17	1	0
Renal Artery Stenosis [description not available]	0	3.06	1	0
Renal Artery Obstruction Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).	0	3.06	1	0
Desmoid [description not available]	0	4.45	1	1
Abdominal Neoplasms New abnormal growth of tissue in the ABDOMEN.	0	4.45	1	1
Multiple Primary Neoplasms [description not available]	0	4.45	1	1
Retroperitoneal Neoplasms New abnormal growth of tissue in the RETROPERITONEAL SPACE.	0	4.45	1	1
Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.	0	5.72	2	1
Thoracic Neoplasms New abnormal growth of tissue in the THORAX.	0	4.45	1	1
Fibromatosis, Aggressive A childhood counterpart of abdominal or extra-abdominal desmoid tumors, characterized by firm subcutaneous nodules that grow rapidly in any part of the body but do not metastasize. The adult form of abdominal fibromatosis is FIBROMATOSIS, ABDOMINAL. (Stedman, 25th ed)	0	4.45	1	1
Response Evaluation Criteria in Solid Tumors An internationally recognized set of published rules used for evaluation of cancer treatment that define when tumors found in cancer patients improve, worsen, or remain stable during treatment. These criteria are based specifically on the response of the tumor(s) to treatment, and not on the overall health status of the patient resulting from treatment.	0	4.45	1	1
Anemia, Hemolytic, Acquired [description not available]	0	2.96	1	0
Germinoblastoma [description not available]	0	2.96	1	0
Dysmyelopoietic Syndromes [description not available]	0	3.67	3	0
B-Cell Chronic Lymphocytic Leukemia [description not available]	0	3.37	2	0
Purpura, Thrombopenic [description not available]	0	2.96	1	0
Anemia, Hemolytic A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).	0	2.96	1	0
Lymphoma A general term for various neoplastic diseases of the lymphoid tissue.	0	2.96	1	0
Myelodysplastic Syndromes Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.	0	3.67	3	0
Purpura, Thrombocytopenic Any form of purpura in which the PLATELET COUNT is decreased. Many forms are thought to be caused by immunological mechanisms.	0	2.96	1	0
Leukemia, Lymphocytic, Chronic, B-Cell A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.	0	3.37	2	0
Inappropriate GH Secretion Syndrome (Acromegaly) [description not available]	0	2.04	1	0
BH4 Deficiency [description not available]	0	2.04	1	0
Acromegaly A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)	0	2.04	1	0
Phenylketonurias A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).	0	2.04	1	0
Pulmonary Sarcoidosis [description not available]	0	2.05	1	0
Sarcoidosis, Pulmonary Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)	0	2.05	1	0
Congestive Ophthalmopathy [description not available]	0	2.05	1	0
Graves Ophthalmopathy An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.	0	2.05	1	0
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	0	3.55	8	0
Serositis Inflammation of a serous membrane.	0	2.96	1	0
Anemia, Hypoplastic [description not available]	0	2.05	1	0
Anemia, Aplastic A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.	0	2.05	1	0
Actinic Keratosis [description not available]	0	2.05	1	0
Keratosis, Actinic White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.	0	2.05	1	0
Cat Diseases Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.	0	2.05	1	0
Paraneoplastic Syndromes In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumor cell metabolites or other products.	0	2.05	1	0
Maculopapular Cutaneous Mastocytosis [description not available]	0	2.05	1	0
Acute Hepatic Failure [description not available]	0	2.46	2	0
Liver Failure, Acute A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.	0	2.46	2	0
Chromosomal Triplication [description not available]	0	2.05	1	0
Hospital-Acquired Condition [description not available]	0	2.05	1	0
Emesis [description not available]	0	3.44	1	1
Vomiting The forcible expulsion of the contents of the STOMACH through the MOUTH.	0	3.44	1	1
Anomalous Ventricular Excitation Syndrome [description not available]	0	2.05	1	0
Wolff-Parkinson-White Syndrome A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.	0	2.05	1	0
Hepatic Insufficiency Conditions in which the LIVER functions fall below the normal ranges. Severe hepatic insufficiency may cause LIVER FAILURE or DEATH. Treatment may include LIVER TRANSPLANTATION.	0	4.35	1	1
Connective Tissue Disease, Mixed [description not available]	0	2.05	1	0
Cholera Infantum [description not available]	0	2.94	1	0
Acne Rosacea [description not available]	0	2.06	1	0
Rosacea A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).	0	2.06	1	0
Merkel Cell Cancer [description not available]	0	2.06	1	0
Carcinoma, Merkel Cell A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)	0	2.06	1	0
Peritoneal Carcinomatosis [description not available]	0	2.07	1	0
Peritoneal Neoplasms Tumors or cancer of the PERITONEUM.	0	2.07	1	0
Thyroid Diseases Pathological processes involving the THYROID GLAND.	0	2.05	1	0
Polyarthritis [description not available]	0	2.06	1	0
Autoimmune Disease [description not available]	0	2.06	1	0
Arthritis Acute or chronic inflammation of JOINTS.	0	2.06	1	0
Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.	0	2.06	1	0
Granuloma, Hodgkin [description not available]	0	2.06	1	0
Hodgkin Disease A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.	0	2.06	1	0
Carbon Tetrachloride Poisoning Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.	0	2.06	1	0
Cardiac Arrest, Sudden [description not available]	0	2.06	1	0
Death, Sudden, Cardiac Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)	0	2.06	1	0
Central Hypothyroidism [description not available]	0	2.06	1	0
Hypothyroidism A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.	0	2.06	1	0
Constriction, Pathological [description not available]	0	3.85	2	1
Constriction, Pathologic The condition of an anatomical structure's being constricted beyond normal dimensions.	0	3.85	2	1
Giant Cell Tumors Tumors of bone tissue or synovial or other soft tissue characterized by the presence of giant cells. The most common are giant cell tumor of tendon sheath and GIANT CELL TUMOR OF BONE.	1	5.86	2	0
Chronic Kidney Failure [description not available]	0	2.76	3	0
Hypertrophy General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).	0	2.06	1	0
Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.	0	2.76	3	0
Dysphagia [description not available]	0	4.37	1	1
Deglutition Disorders Difficulty in SWALLOWING which may result from neuromuscular disorder or mechanical obstruction. Dysphagia is classified into two distinct types: oropharyngeal dysphagia due to malfunction of the PHARYNX and UPPER ESOPHAGEAL SPHINCTER; and esophageal dysphagia due to malfunction of the ESOPHAGUS.	0	4.37	1	1
Bone Cancer [description not available]	0	2.06	1	0
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES.	0	2.06	1	0
Hairy Cell Leukemia [description not available]	0	2.07	1	0
Leukemia, Hairy Cell A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.	0	2.07	1	0
HIV Coinfection [description not available]	0	2.06	1	0
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).	0	2.06	1	0
Anaphylactic Reaction [description not available]	0	2.07	1	0
Allergic Reaction [description not available]	0	2.07	1	0
Anaphylaxis An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.	0	2.07	1	0
Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.	0	2.07	1	0
Kidney, Polycystic [description not available]	0	2.07	1	0
Polycystic Kidney Diseases Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.	0	2.07	1	0
Leukocytosis A transient increase in the number of leukocytes in a body fluid.	0	3.84	2	0
Hypertrophy, Right Ventricular Enlargement of the RIGHT VENTRICLE of the heart. This increase in ventricular mass is often attributed to PULMONARY HYPERTENSION and is a contributor to cardiovascular morbidity and mortality.	0	2.07	1	0
Anoxemia [description not available]	0	2.07	1	0
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	0	2.07	1	0
Chromosome Deletion Actual loss of portion of a chromosome.	0	2.07	1	0
Bone Diseases Diseases of BONES.	0	2.07	1	0
Diarrhea An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.	0	2.99	1	0
Injury, Ischemia-Reperfusion [description not available]	0	2.07	1	0
Reperfusion Injury Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.	0	2.07	1	0
Muscle Spasm [description not available]	0	2.07	1	0
Spasm An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.	0	2.07	1	0
Acoustic Neuroma [description not available]	0	2.07	1	0
Cold Fingers, Hereditary [description not available]	0	2.07	1	0
Raynaud Disease An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.	0	2.07	1	0
Tenosynovitis Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.	0	3	1	0
Phlegmon [description not available]	0	2.08	1	0
Cellulitis An acute, diffuse, and suppurative inflammation of loose connective tissue, particularly the deep subcutaneous tissues, and sometimes muscle, which is most commonly seen as a result of infection of a wound, ulcer, or other skin lesions.	0	2.08	1	0
Precordial Catch [description not available]	0	2.08	1	0
Breathlessness [description not available]	0	2.08	1	0
Chest Pain Pressure, burning, or numbness in the chest.	0	2.08	1	0
Dyspnea Difficult or labored breathing.	0	2.08	1	0
Disease A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.	0	2.08	1	0
Abnormal Karyotype A variation from the normal set of chromosomes characteristic of a species.	0	2.08	1	0
Mast-Cell Leukemia [description not available]	0	2.03	1	0
Leukemia, Mast-Cell A form of systemic mastocytosis (MASTOCYTOSIS, SYSTEMIC) characterized by the presence of large numbers of tissue MAST CELLS in the peripheral blood without skin lesions. It is a high-grade LEUKEMIA disease with bone marrow smear of	0	2.03	1	0
Enlarged Liver [description not available]	0	2.95	1	0
Enlarged Spleen [description not available]	0	2.95	1	0
Fasting Hypoglycemia HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.	0	2.03	1	0
Hypoglycemia A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.	0	2.03	1	0
Leukemia, Lymphocytic [description not available]	0	2.03	1	0
Leukemia, Lymphoid Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts.	0	2.03	1	0
Chromosomal Instability An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.	0	2.03	1	0
Monosomy The condition in which one chromosome of a pair is missing. In a normally diploid cell it is represented symbolically as 2N-1.	0	2.03	1	0
Experimental Leukemia [description not available]	0	2.44	2	0
Cancer of Granulosa Cells [description not available]	0	2.04	1	0
Complications of Diabetes Mellitus [description not available]	0	2.04	1	0
Acute Febrile Neutrophilic Dermatosis [description not available]	0	2.04	1	0
ATLL [description not available]	0	2.04	1	0
Leukemia-Lymphoma, Adult T-Cell Aggressive T-Cell malignancy with adult onset, caused by HUMAN T-LYMPHOTROPIC VIRUS 1. It is endemic in Japan, the Caribbean basin, Southeastern United States, Hawaii, and parts of Central and South America and sub-Saharan Africa.	0	2.04	1	0

s 1033

Cross-References

Synonyms (117)

Research Excerpts

Toxicity

Pharmacokinetics

Compound-Compound Interactions

Bioavailability

Dosage Studied

Roles (3)

Drug Classes (6)

Pathways (1)

Protein Targets (511)

Potency Measurements

Inhibition Measurements

Activation Measurements

Biological Processes (3190)

Molecular Functions (618)

Ceullar Components (481)

Bioassays (1197)

Research

Studies (1,372)

Market Indicators

Research Demand Index: 22.20

Study Types

s 1033

Cross-References

Synonyms (117)

Research Excerpts

Toxicity

Pharmacokinetics

Compound-Compound Interactions

Bioavailability

Dosage Studied

Roles (3)

Drug Classes (6)

Pathways (1)

Protein Targets (511)

Potency Measurements

Inhibition Measurements

Activation Measurements

Biological Processes (3190)

Molecular Functions (618)

Ceullar Components (481)

Bioassays (1197)

Research

Studies (1,372)

Market Indicators

Research Demand Index: 22.20

Study Types

Related Drugs (1,841)

Related Conditions (634)