Page last updated: 2024-08-07 17:11:23
Vitamin D3 receptor
A vitamin D3 receptor that is encoded in the genome of cow. [OMA:Q28037, PRO:DNx]
Synonyms
VDR;
1,25-dihydroxyvitamin D3 receptor;
Nuclear receptor subfamily 1 group I member 1
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| calcitriol | Bos taurus (cattle) | IC50 | 0.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| calcitriol | Bos taurus (cattle) | EC50 | 0.0001 | 2 | 2 |
Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists.Journal of medicinal chemistry, , 01-14, Volume: 64, Issue:1, 2021
A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.Journal of medicinal chemistry, , Mar-12, Volume: 52, Issue:5, 2009
22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor.Journal of medicinal chemistry, , Mar-08, Volume: 50, Issue:5, 2007