erucylphosphocholine profile

erucylphosphocholine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	6439461
CHEMBL ID	229567
SCHEMBL ID	4064798
MeSH ID	M0202269

Synonym
ethanaminium, 2-(((13-docosenyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethyl-, hydroxide, inner salt, (z)-
erucylphosphocholine
CHEMBL229567
[(z)-docos-13-enyl] 2-(trimethylazaniumyl)ethyl phosphate
143317-74-2
SCHEMBL4064798
DTXSID601315365

Excerpt	Reference	Relevance
"Erucylphosphocholine (ErPC) is a promising candidate for the treatment of human brain tumors. "	( Structure-activity relationships of alkylphosphocholine derivatives: antineoplastic action on brain tumor cell lines in vitro. Eibl, H; Erdlenbruch, B; Hammersen, K; Jendrossek, V; Krügener, R; Kugler, W; Lakomek, M, 2002)	1.76
"Erucylphosphocholine (ErPC) is a promising anti-neoplastic drug for the treatment of malignant brain tumours. "	( Erucylphosphocholine-induced apoptosis in glioma cells: involvement of death receptor signalling and caspase activation. Eibl, H; Erdlenbruch, B; Heinemann, D; Jünemann, A; Kugler, W; Lakomek, M, 2002)	3.2
"Erucylphosphocholine (ErPC) is a promising antineoplastic drug for the treatment of malignant brain tumors. "	( MAP kinase pathways involved in glioblastoma response to erucylphosphocholine. Eibl, H; Erdlenbruch, B; Jendrossek, V; Kugler, W; Lakomek, M; Otten, K, 2004)	2.01

Excerpt	Reference	Relevance
"Erucylphosphocholine (ErPC) has been shown to exert strong antineoplastic effects against various brain tumor cell lines in vitro. "	( Increased delivery of erucylphosphocholine to C6 gliomas by chemical opening of the blood-brain barrier using intracarotid pentylglycerol in rats. Eibl, H; Erdlenbruch, B; Jendrossek, V; Kugler, W; Lakomek, M, 2002)	2.07

Excerpt	Reference	Relevance
" Adverse effects on the anterior and posterior segment were assessed by slit-lamp biomicroscopy and ophthalmoscopy."	( Toxicity study of erucylphosphocholine in a rat model. Blatsios, G; Eibl, KH; May, CA; Rejdak, R; Schuettauf, F; Shinoda, K; Thaler, S; Welge-Lussen, U, 2005)	0.66

Excerpt	Reference	Relevance
" Moreover, activity of the survival kinase PKB/Akt was downregulated upon treatment with ErPC/ErPC3 alone or in combination with ionizing radiation."	( Increased cytotoxicity of ionizing radiation in combination with membrane-targeted apoptosis modulators involves downregulation of protein kinase B/Akt-mediated survival-signaling. Belka, C; Eibl, H; Faltin, H; Handrick, R; Jendrossek, V; Rübel, A, 2006)	0.33

Excerpt	Reference	Relevance
"To develop a stable micellar formulation of vitamin K for oral delivery, because the commercial and clinically used formulation of vitamin K (Konakion® MM) destabilizes at gastric pH resulting in low bioavailability of this vitamin in neonates with cholestasis."	( A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Hennink, WE; Jaspers, TC; Sun, F; van Hasselt, PM; van Nostrum, CF, 2016)	0.43

Bioassays (17)

Assay ID	Title	Year	Journal	Article
AID288954	Antifungal activity against Cryptococcus neoformans ATCC 90112	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID633816	Cytotoxicity against human KATO III cells after 24 hrs by FACS analysis	2012	European journal of medicinal chemistry, Jan, Volume: 47, Issue:1	Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation.
AID633734	Inhibition of Akt phosphorylation in insulin-stimulated human A549 cells at 10 uM treated 2 hrs before insulin stimulation measured after 30 mins by ELISA	2012	European journal of medicinal chemistry, Jan, Volume: 47, Issue:1	Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation.
AID288968	Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID633814	Cytotoxicity against human A549 cells after 24 hrs by FACS analysis	2012	European journal of medicinal chemistry, Jan, Volume: 47, Issue:1	Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation.
AID288970	Antibacterial activity against vancomycin-resistant Enterococcus ATCC 51299 after 24 hrs	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288964	Toxicity assessed as haemolytic activity against human erythrocytes at 44 uM	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288969	Antibacterial activity against methicillin-resistant Staphylococcus aureus after 24 hrs	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID633813	Inhibition of Akt phosphorylation in insulin-stimulated human A549 cells treated 2 hrs before insulin stimulation measured after 30 mins by ELISA	2012	European journal of medicinal chemistry, Jan, Volume: 47, Issue:1	Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation.
AID633815	Cytotoxicity against human MCF7 cells after 24 hrs by FACS analysis	2012	European journal of medicinal chemistry, Jan, Volume: 47, Issue:1	Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation.
AID288965	Toxicity assessed as haemolytic activity against human erythrocytes at 17.5 uM	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288967	Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288955	Antifungal activity against Candida albicans ATCC 10231	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288963	Toxicity assessed as haemolytic activity against human erythrocytes at 88 uM	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288961	Toxicity assessed as haemolytic activity against human erythrocytes at 350 uM	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288966	Toxicity assessed as haemolytic activity against human erythrocytes at 3.5 uM	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
AID288962	Toxicity assessed as haemolytic activity against human erythrocytes at 175 uM	2007	Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15	Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	10 (25.64)	18.2507
2000's	19 (48.72)	29.6817
2010's	10 (25.64)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (2.38%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	41 (97.62%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
glycerol Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.	7.41	2	alditol; triol	algal metabolite; detergent; Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; solvent
phosphorylcholine Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.. phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.	6.06	37	phosphocholines	allergen; epitope; hapten; human metabolite; mouse metabolite
edelfosine edelfosine: RN given refers to parent cpd. edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.. 1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.	4.27	5	glycerophosphocholine
miltefosine miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin. miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.	4.83	10	phosphocholines; phospholipid	anti-inflammatory agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antiprotozoal drug; apoptosis inducer; immunomodulator; protein kinase inhibitor
bromodeoxyuridine Bromodeoxyuridine: A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.	2.03	1	pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent
1,2-dipalmitoylphosphatidylcholine 1,2-Dipalmitoylphosphatidylcholine: Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.	2.08	1
glycocholic acid Glycocholic Acid: The glycine conjugate of CHOLIC ACID. It acts as a detergent to solubilize fats for absorption and is itself absorbed.. glycocholic acid : A bile acid glycine conjugate having cholic acid as the bile acid component.. glycocholate : A cholanic acid conjugate anion that is the conjugate base of glycocholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.	2.13	1	bile acid glycine conjugate	human metabolite
methylnitrosourea Methylnitrosourea: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.. N-methyl-N-nitrosourea : A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.	1.98	1	N-nitrosoureas	alkylating agent; carcinogenic agent; mutagen; teratogenic agent
vancomycin Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.	2.03	1	glycopeptide	antibacterial drug; antimicrobial agent; bacterial metabolite
dodecyldimethylamine oxide dodecyldimethylamine oxide: zwitterionic detergent. dodecyldimethylamine N-oxide : A tertiary amine oxide resulting from the formal oxidation of the amino group of dodecyldimethylamine.	2.03	1	tertiary amine oxide	detergent; plant metabolite
4-nitrobenzofurazan 4-nitrobenzofurazan: structure	2.1	1
amoxicillin Amoxicillin: A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.. amoxicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group.	2.03	1	penicillin allergen; penicillin	antibacterial drug
paclitaxel Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).	2	1	taxane diterpenoid; tetracyclic diterpenoid	antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent
1-o-pentylglycerol 1-O-pentylglycerol: an alkylglycerol, increases the transfer of ErPC into the brain	2.01	1
n-octadecylphosphocholine n-octadecylphosphocholine: substrate analog for phospholipase A2	2.4	2
perifosine [no description available]	4.41	6	ammonium betaine; phospholipid	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
hydroxyl radical Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.	1.99	1	oxygen hydride; oxygen radical; reactive oxygen species
1,2-dilauroylphosphatidylcholine 1,2-dilauroylphosphatidylcholine: RN given refers to cpd without isomeric designation. 1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) : A A 1,2-diacyl-sn-glycero-3-phosphocholine(1+) that is the dilauroyl diester of phosphatidiylcholine.	2.03	1	1,2-diacyl-sn-glycero-3-phosphocholine(1+)
oleic acid Oleic Acid: An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed). oleic acid : An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.	2.01	1	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent
dodecylphosphocholine dodecylphosphocholine: phospholipase A2 inhibitor; RN refers to chloride. dodecylphosphocholine : A phosphocholine that is the monododecyl ester of phosphocholine	2.03	1	phosphocholines	detergent
vitamin k semiquinone radical vitamin K semiquinone radical: found in active preparations of vitamin K-dependent carboxylase. vitamin K : Any member of a group of fat-soluble 2-methyl-1,4-napthoquinones that exhibit biological activity against vitamin K deficiency. Vitamin K is required for the synthesis of prothrombin and certain other blood coagulation factors.	2.13	1
amphotericin b Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.	2.03	1	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite
vitamin k 1 Vitamin K 1: A family of phylloquinones that contains a ring of 2-methyl-1,4-naphthoquinone and an isoprenoid side chain. Members of this group of vitamin K 1 have only one double bond on the proximal isoprene unit. Rich sources of vitamin K 1 include green plants, algae, and photosynthetic bacteria. Vitamin K1 has antihemorrhagic and prothrombogenic activity.. phylloquinone : A member of the class of phylloquinones that consists of 1,4-naphthoquinone having methyl and phytyl groups at positions 2 and 3 respectively. The parent of the class of phylloquinones.	2.13	1	phylloquinones; vitamin K	cofactor; human metabolite; plant metabolite
lysophosphatidylcholines lysophosphatidylcholine : An acylglycerophosphocholine resulting from partial hydrolysis of a phosphatidylcholine, which removes one of the fatty acyl groups. The structure is depicted in the image where R1 = acyl, R2 = H or where R1 = H, R2 = acyl.	2	1	1-O-acyl-sn-glycero-3-phosphocholine
1,2-oleoylphosphatidylcholine 1,2-oleoylphosphatidylcholine: RN given refers to (Z,Z)-isomer. dioleoyl phosphatidylcholine : A phosphatidylcholine in which the phosphatidyl acyl groups are both oleoyl.	2.42	2	phosphatidylcholine(1+)
sulfur Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.	2.01	1	chalcogen; nonmetal atom	macronutrient
dioleoylphosphatidic acid dioleoylphosphatidic acid: RN given refers to (Z)-isomer. dioleoyl phosphatidic acid : A phosphatidic acid in which the phosphatidyl acyl groups are both oleoyl.	2	1	1,2-bis(octadec-9-enoyl)phosphatidic acid
erucylphospho-n,n,n-trimethylpropylammonium erucylphospho-N,N,N-trimethylpropylammonium: an antineoplastic agent	3.56	2
oxadiazoles Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms.	2.1	1
cytochrome c-t Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.	2.02	1
phosphatidylcholines Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	2.69	3	1,2-diacyl-sn-glycero-3-phosphocholine
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone: an interleukin-1beta converting enzyme (ICE)-like protease inhibitor	2.01	1
trypan blue Trypan Blue: A diazo-naphthalene sulfonate that is widely used as a stain.. trypan blue : An organosulfonate salt that is the tetrasodium salt of 3,3'-[(3,3'-dimethylbiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis(5-amino-4-hydroxynaphthalene-2,7-disulfonic acid).	2.02	1

Condition	Relationship Strength	Studies
Cancer of Prostate [description not available]	2.1	1
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	2.1	1
Schistosoma mansoni Infection [description not available]	2.1	1
Schistosomiasis mansoni Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.	2.1	1
Cancer of Ovary [description not available]	2.04	1
Cancer of Endometrium [description not available]	2.04	1
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.	2.04	1
Endometrial Neoplasms Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.	2.04	1
Hepatocellular Carcinoma [description not available]	2.05	1
Cancer of Liver [description not available]	2.05	1
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	2.05	1
Liver Neoplasms Tumors or cancer of the LIVER.	2.05	1
Cancer of the Uterus [description not available]	2.06	1
Choriocarcinoma A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).	7.06	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	2.06	1
Uterine Neoplasms Tumors or cancer of the UTERUS.	2.06	1
Benign Neoplasms [description not available]	3	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	3	1
Benign Neoplasms, Brain [description not available]	3.1	5
Astrocytoma, Grade IV [description not available]	2.93	4
Extravascular Hemolysis [description not available]	2.01	1
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.	3.1	5
Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.	7.93	4
Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.	2.01	1
Glial Cell Tumors [description not available]	2.7	3
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)	2.7	3
Breast Cancer [description not available]	2.02	1
Breast Neoplasms Tumors or cancer of the human BREAST.	2.02	1
Anaplastic Astrocytoma [description not available]	2.03	1
Astrocytoma Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)	2.03	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.03	1
Retinal Pigment Epithelial Detachment [description not available]	2.44	2
Retinal Detachment Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).	2.44	2
Proliferative Vitreoretinopathy [description not available]	2.03	1
Vitreoretinopathy, Proliferative Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.	2.03	1
Experimental Mammary Neoplasms [description not available]	2.39	2
Cadaver A dead body, usually a human body.	2.4	2
Bladder Cancer [description not available]	2	1
Carcinoma, Anaplastic [description not available]	2	1
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER.	2	1
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.	2	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	2	1
Injury, Myocardial Reperfusion [description not available]	1.99	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2	1

erucylphosphocholine

Description

Cross-References

Synonyms (7)

Research Excerpts

Overview

Effects

Toxicity

Compound-Compound Interactions

Bioavailability

Bioassays (17)

Research

Studies (39)

Market Indicators

Research Demand Index: 10.74

Study Types

erucylphosphocholine

Description

Cross-References

Synonyms (7)

Research Excerpts

Overview

Effects

Toxicity

Compound-Compound Interactions

Bioavailability

Bioassays (17)

Research

Studies (39)

Market Indicators

Research Demand Index: 10.74

Study Types

Related Drugs (33)

Related Conditions (44)