A lanosterol synthase that is encoded in the genome of rat. [OMA:P48450, PRO:DNx]
EC 5.4.99.7;
2,3-epoxysqualene--lanosterol cyclase;
Oxidosqualene--lanosterol cyclase;
OSC
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 3-(biphenyl-4-yl)-3-hydroxyquinuclidine | Rattus norvegicus (Norway rat) | IC50 | 0.1000 | 1 | 2 |
| sd-208 | Rattus norvegicus (Norway rat) | IC50 | 0.0530 | 1 | 1 |
| 4,4,10-trimethyl-trans-decal-3-ol | Rattus norvegicus (Norway rat) | IC50 | 9.0000 | 1 | 1 |