dacarbazine has been researched along with Sensitivity and Specificity in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (10.53) | 18.2507 |
| 2000's | 15 (39.47) | 29.6817 |
| 2010's | 19 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, SH; Kang, KM; Kim, JH; Lim, WH; Nam, JG; Sohn, CH; Yoo, RE; Yun, TJ | 1 |
| Agrawal, JP; Erickson, BJ; Korfiatis, P; Perry, LA | 1 |
| Farinotti, R; Fernandez, C; Goldwirt, L; Zahr, N | 1 |
| Aaløkken, TM; Bogsrud, TV; Geier, OM; Hagtvedt, T; Holte, H; Lund, KV; Løndalen, AM; Seierstad, T; Smith, HJ | 1 |
| Athawale, R; Bajaj, A; Jain, D; Shrikhande, S | 1 |
| Baden, A; Doi, Y; Kanagawa, M; Mizoi, K; Oka, S; Ono, M; Ono, T; Sasajima, T; Shimizu, H | 1 |
| Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Sohn, CH; Yoo, RE; Yun, TJ | 1 |
| Bulik, M; Jancalek, R; Kazda, T; Slampa, P | 1 |
| Crippa, F; Galldiks, N; Hofer, S; Nowosielski, M; Roelcke, U; Roth, P; Rudà, R; Soffietti, R; Weller, M; Wyss, MT | 1 |
| Arús, C; Candiota, AP; Ciezka, M; Delgado-Goñi, T; Fernández, F; Julià-Sapé, M; Lisboa, PJ; Olier, I; Ortega-Martorell, S; Pumarola, M | 1 |
| Liu, Y; Yang, Y; Zhang, W | 1 |
| Aikawa, E; Chen, JW; Figueiredo, JL; McCann, CM; Waterman, P; Weissleder, R | 1 |
| Andrasi, M; Bustos, R; Gaspar, A; Gomez, FA; Klekner, A | 1 |
| Elandt, K; Heinzl, H; Marosi, C; Preusser, M; Schwarzinger, I | 1 |
| Payer, F | 1 |
| Berkhof, J; Bosma, I; Buter, J; Heimans, JJ; Hoekstra, OS; Lagerwaard, FJ; Noske, DP; Postma, TJ; Reijneveld, JC; Sanchez, E; Sizoo, EM; Vos, MJ | 1 |
| Bolacchi, F; Danieli, R; Della Gatta, F; Gaspari, E; Mancini, A; Orlacchio, A; Ragano Caracciolo, C; Schillaci, O; Simonetti, G | 1 |
| Gerson, SL; Liu, L; Savvides, P; Xu, Y; Yang, S | 1 |
| Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Lee, WJ; Park, CK; Park, SH; Sohn, CH; Yi, KS | 1 |
| Andreo, FC; Navarro, JT; Ribera, JM; Torrent, A | 1 |
| Advani, R; Ambinder, RF; Bartlett, NL; Cheson, BD; Fisher, RI; Gascoyne, RD; Gellert, LL; Gordon, LI; Hong, F; Horning, SJ; Hsieh, WS; Kahl, BS; Kanakry, JA; Lemas, MV; Li, H; Miller, TP; Stiff, P; Tan, KL | 1 |
| Ambrosetti, A; Benedetti, F; Nadali, G; Pizzolo, G; Ricetti, MM; Trolese, A; Visco, C; Zanotti, R | 1 |
| Baayen, HC; Barkhof, F; Boogerd, W; Castelijns, JA; Elkhuizen, PH; Heimans, JJ; Postma, TJ; Uitdehaag, BM; Vos, MJ | 1 |
| Caldwell, D; Kelley, MR; Rinne, M | 1 |
| Friedman, HS; Grubbs, E; Ko, SH; Pruitt, SK; Tyler, DS; Ueno, T | 1 |
| Chiang, SY; Huang, TH; Lin, HY; Swenberg, JA; Uang, SN; Wei, YC; Wu, HD; Wu, KY | 1 |
| Burghaus, L; Galldiks, N; Heiss, WD; Herholz, K; Jacobs, AH; Kracht, LW; Thomas, A | 1 |
| Guadagnolo, BA; Kuntz, KM; Mauch, PM; Ng, AK; Punglia, RS | 1 |
| Hegi, ME; Stupp, R | 1 |
| Attilio, G; Cristina, L; Edoardo, DN; Giuseppe, L; Loredana, G; Vincenzo, L | 1 |
| Friedman, HS; Maxwell, J | 1 |
| Biollax, J; Decosterd, LA; Gander, M; Lejeune, F; Leyvraz, S; Shen, F | 1 |
| Belladonna, ML; Bianchi, R; Fioretti, MC; Grohmann, U; Puccetti, P | 1 |
| Kim, HK; Likhari, P; Lim, J; Lin, CC; Marco, A; Nomeir, AA; Parker, D; Statkevich, P; Veals, J | 1 |
| Bonmassar, E; De Vecchis, L; Faraoni, I; Graziani, G; Masci, G; Shay, JW; Turriziani, M | 1 |
| Braybrooke, JP; Crawley, JE; Harris, AL; Houlbrook, S; O'Byrne, KJ; Propper, DJ; Shuker, DE; Stratford, IJ; Talbot, DC | 1 |
| Hall, CN; Harrison, KL; Lees, NP; Margison, GP; Povey, AC; Wood, M | 1 |
| Fueyo, J; Gomez-Manzano, C; Groves, MD; He, J; Hu, M; Lemoine, MG; Liu, TJ; Mitlianga, P; Yung, AW | 1 |
1 review(s) available for dacarbazine and Sensitivity and Specificity
| Article | Year |
|---|---|
[Pseudoprogression or pseudoresponse: a challenge for the diagnostic imaging in Glioblastoma multiforme].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brain; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Diagnosis, Differential; Diagnostic Imaging; Diffusion Magnetic Resonance Imaging; Disease Progression; Glioblastoma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Positron-Emission Tomography; Radiation Injuries; Sensitivity and Specificity; Temozolomide; Tumor Burden | 2011 |
7 trial(s) available for dacarbazine and Sensitivity and Specificity
| Article | Year |
|---|---|
Diffusion-weighted MRI compared to FDG PET/CT for assessment of early treatment response in lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Diffusion Magnetic Resonance Imaging; Doxorubicin; Early Diagnosis; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphoma; Male; Middle Aged; Multimodal Imaging; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed; Treatment Outcome; Vinblastine; Young Adult | 2015 |
The Diagnostic Ability of Follow-Up Imaging Biomarkers after Treatment of Glioblastoma in the Temozolomide Era: Implications from Proton MR Spectroscopy and Apparent Diffusion Coefficient Mapping.
Topics: Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Tensor Imaging; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Middle Aged; Molecular Imaging; Neoplasm Recurrence, Local; Outcome Assessment, Health Care; Prognosis; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Treatment Outcome | 2015 |
MRI and thallium-201 SPECT in the prediction of survival in glioma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Netherlands; Prevalence; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Survival Rate; Temozolomide; Thallium Radioisotopes; Treatment Outcome; Young Adult | 2012 |
Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Artifacts; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glioma; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Treatment Outcome; Young Adult | 2012 |
Plasma Epstein-Barr virus DNA predicts outcome in advanced Hodgkin lymphoma: correlative analysis from a large North American cooperative group trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; DNA, Viral; Doxorubicin; Epstein-Barr Virus Infections; Etoposide; Female; Herpesvirus 4, Human; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Neoadjuvant Therapy; North America; Prednisone; Prognosis; Sensitivity and Specificity; Vinblastine; Vincristine; Young Adult | 2013 |
Use of 11C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Glioma; Humans; Male; Methionine; Middle Aged; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Treatment Outcome | 2006 |
Ovarian function after cancer treatment in young women affected by Hodgkin disease (HD).
Topics: Adolescent; Adult; Amenorrhea; Anti-Mullerian Hormone; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Dexamethasone; Doxorubicin; Female; Follicle Stimulating Hormone; Glycoproteins; Hodgkin Disease; Humans; Infertility, Female; Inhibins; Luteinizing Hormone; Mechlorethamine; Ovarian Follicle; Ovary; Predictive Value of Tests; Prednisolone; Prednisone; Primary Ovarian Insufficiency; Procarbazine; Sensitivity and Specificity; Survivors; Testicular Hormones; Time Factors; Triptorelin Pamoate; Ultrasonography; Vinblastine; Vincristine | 2007 |
30 other study(ies) available for dacarbazine and Sensitivity and Specificity
| Article | Year |
|---|---|
Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast-Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Che
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Contrast Media; Dacarbazine; Disease Progression; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Reproducibility of Results; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Temozolomide | 2017 |
Increased signal intensity within glioblastoma resection cavities on fluid-attenuated inversion recovery imaging to detect early progressive disease in patients receiving radiotherapy with concomitant temozolomide therapy.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Retrospective Studies; Sensitivity and Specificity; Temozolomide | 2018 |
Development of a new UPLC-MSMS method for the determination of temozolomide in mice: application to plasma pharmacokinetics and brain distribution study.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dacarbazine; Female; Least-Squares Analysis; Mice; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temozolomide; Tissue Distribution | 2013 |
Double-salting out assisted liquid-liquid extraction (SALLE) HPLC method for estimation of temozolomide from biological samples.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Dacarbazine; Humans; Linear Models; Liquid-Liquid Extraction; Reproducibility of Results; Sensitivity and Specificity; Sodium Chloride; Sulfates; Temozolomide | 2014 |
Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-β, and/or bevacizumab for glioblastoma.
Topics: Amino Acids; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Humans; Interferon-beta; Male; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Rats, Nude; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Tissue Distribution; Treatment Outcome | 2015 |
Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value.
Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbazine; Diffusion Magnetic Resonance Imaging; Disease Progression; Ependyma; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Sensitivity and Specificity; Temozolomide; Young Adult | 2015 |
Amino acid positron emission tomography to monitor chemotherapy response and predict seizure control and progression-free survival in WHO grade II gliomas.
Topics: Adult; Amino Acids; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Grading; Positron-Emission Tomography; ROC Curve; Seizures; Sensitivity and Specificity; Temozolomide; Young Adult | 2016 |
MRSI-based molecular imaging of therapy response to temozolomide in preclinical glioblastoma using source analysis.
Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Female; Glioblastoma; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Molecular Imaging; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Treatment Outcome | 2016 |
Validated hydrophilic interaction LC-MS/MS method for simultaneous quantification of dacarbazine and 5-amino-4-imidazole-carboxamide in human plasma.
Topics: Aminoimidazole Carboxamide; Calibration; Chromatography, High Pressure Liquid; Dacarbazine; Humans; Hydrogen-Ion Concentration; Molecular Structure; Sensitivity and Specificity; Tandem Mass Spectrometry; Water | 2008 |
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma; Humans; Magnetic Resonance Imaging; Male; Mice; Microscopy, Fluorescence; Reproducibility of Results; Sensitivity and Specificity; Subtraction Technique; Temozolomide; Treatment Outcome | 2009 |
Analysis and stability study of temozolomide using capillary electrophoresis.
Topics: Aminoimidazole Carboxamide; Antineoplastic Agents, Alkylating; Chromatography, Micellar Electrokinetic Capillary; Dacarbazine; Drug Stability; Half-Life; Humans; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Temperature; Water | 2010 |
Immature and absolute platelet count changes and thrombocytopenia in malignant glioma.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Blood Platelets; Dacarbazine; Female; Glioma; Humans; Male; Middle Aged; Platelet Count; Prospective Studies; Sensitivity and Specificity; Temozolomide; Thrombocytopenia; Young Adult | 2011 |
Role of [18F]-FDG-PET/MDCT in evaluating early response in patients with Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Female; Fluorodeoxyglucose F18; Hodgkin Disease; Humans; Male; Multimodal Imaging; Positron-Emission Tomography; Predictive Value of Tests; Prognosis; Radiopharmaceuticals; Retrospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed; Treatment Outcome; Vinblastine | 2012 |
Development and validation of an LC-MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzaldehydes; Chromatography, Liquid; Clinical Trials, Phase I as Topic; Dacarbazine; Drug Stability; Humans; Hydroxylamines; Linear Models; Liquid-Liquid Extraction; Neoplasms; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temozolomide | 2012 |
[Sarcoidosis-like reaction after treatment with doxorubicin, bleomycin, vinblastine and dacarbazine in a patient with Hodgkin's lymphoma].
Topics: Acute-Phase Proteins; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Diagnosis, Differential; Disease Progression; Doxorubicin; False Positive Reactions; Female; Granuloma; Hodgkin Disease; Humans; Lymphadenitis; Multimodal Imaging; Positron-Emission Tomography; Sarcoidosis; Sensitivity and Specificity; Tomography, X-Ray Computed; Vinblastine | 2013 |
Serum levels of soluble CD30 improve International Prognostic Score in predicting the outcome of advanced Hodgkin's lymphoma.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy, Needle; Bleomycin; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Hodgkin Disease; Humans; International Cooperation; Ki-1 Antigen; Male; Mechlorethamine; Middle Aged; Multivariate Analysis; Neoplasm Staging; Predictive Value of Tests; Prednisone; Procarbazine; Prognosis; Proportional Hazards Models; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Survival Rate; Vinblastine; Vincristine | 2002 |
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Dacarbazine; Ependymoma; Female; Glioblastoma; Glioma; Humans; Image Enhancement; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Observer Variation; Oligodendroglioma; Paclitaxel; Procarbazine; Sensitivity and Specificity; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Vincristine | 2003 |
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Topics: Adenoviridae; Alkylating Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Therapy; Genetic Vectors; Humans; Hydroxylamines; Immunohistochemistry; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Oligonucleotides; Sensitivity and Specificity; Sulfuric Acid Esters; Temozolomide; Time Factors | 2004 |
Temozolomide is a novel regional infusion agent for the treatment of advanced extremity melanoma.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Alkylating; Chemotherapy, Cancer, Regional Perfusion; Dacarbazine; Disease Models, Animal; Dose-Response Relationship, Drug; Extremities; Female; Infusions, Parenteral; Melanoma; Melphalan; Probability; Random Allocation; Rats; Rats, Nude; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Skin Neoplasms; Survival Rate; Temozolomide; Transplantation, Heterologous; Treatment Outcome | 2004 |
Analysis of 7-methylguanine using isotope dilution and gas chromatography/electron-capture negative chemical ionization mass spectrometry.
Topics: Animals; Antineoplastic Agents, Alkylating; Carbon Isotopes; Dacarbazine; DNA Adducts; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Male; Mice; Mice, Inbred C57BL; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cost-Benefit Analysis; Dacarbazine; Decision Support Techniques; Doxorubicin; Hodgkin Disease; Humans; Life Expectancy; Markov Chains; Neoplasm Staging; Population Surveillance; Predictive Value of Tests; Quality-Adjusted Life Years; Sensitivity and Specificity; Survival Analysis; Tomography, X-Ray Computed; Vinblastine | 2006 |
Methylguanine methyltransferase testing in glioblastoma: when and how?
Topics: Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm Staging; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Retrospective Studies; Sensitivity and Specificity; Survival Rate; Temozolomide | 2007 |
The fallacy of single-agent chemotherapy for cancer.
Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Sensitivity and Specificity; Temozolomide | 2007 |
Determination of temozolomide in human plasma and urine by high-performance liquid chromatography after solid-phase extraction.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Dacarbazine; Drug Stability; Humans; Hydrogen-Ion Concentration; Pilot Projects; Sensitivity and Specificity; Temozolomide | 1995 |
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815.
Topics: Amino Acid Sequence; Animals; Antigens, Neoplasm; Antigens, Viral; Antineoplastic Agents; Base Sequence; CD8-Positive T-Lymphocytes; Cloning, Molecular; Dacarbazine; DNA, Viral; Female; Genes, env; Histocompatibility Antigens Class I; Hypersensitivity, Delayed; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Molecular Sequence Data; Neoplasm Proteins; Point Mutation; Polymerase Chain Reaction; Retroviridae Proteins; Sensitivity and Specificity; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; T-Lymphocytes, Cytotoxic; Viral Envelope Proteins | 1996 |
High-performance liquid chromatographic determination and stability of 5-(3-methyltriazen-1-yl)-imidazo-4-carboximide, the biologically active product of the antitumor agent temozolomide, in human plasma.
Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Chromatography, High Pressure Liquid; Circadian Rhythm; Dacarbazine; Drug Stability; Freezing; Half-Life; Humans; Linear Models; Osmolar Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Temozolomide; Temperature; Time Factors | 1997 |
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Cell Division; Cell Survival; Cisplatin; Dacarbazine; Densitometry; Doxorubicin; Humans; Jurkat Cells; Polymerase Chain Reaction; Sensitivity and Specificity; Telomerase; Temozolomide; Tumor Cells, Cultured; U937 Cells | 1997 |
Evaluation of the alkaline comet assay and urinary 3-methyladenine excretion for monitoring DNA damage in melanoma patients treated with dacarbazine and tamoxifen.
Topics: Adenine; Adult; Aged; Antineoplastic Agents, Alkylating; Comet Assay; Dacarbazine; DNA Damage; Female; Humans; Lymphocytes; Male; Melanoma; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Skin Neoplasms | 2000 |
Development and application of a sensitive and rapid immunoassay for the quantitation of N7-methyldeoxyguanosine in DNA samples.
Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Brain; Dacarbazine; Deoxyguanosine; DNA Adducts; DNA Methylation; Immunoassay; Liver; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; Sensitivity and Specificity; Temozolomide; Thymus Gland | 2001 |
Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.
Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Proteins; Cell Survival; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dacarbazine; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Gene Transfer Techniques; Glioma; Humans; Inhibitory Concentration 50; Sensitivity and Specificity; Temozolomide; Transcription Factors; Tumor Cells, Cultured | 2001 |