Page last updated: 2024-08-07 20:17:59
E3 ubiquitin-protein ligase Mdm2
An E3 ubiquitin-protein ligase Mdm2 that is encoded in the genome of mouse. [OMA:P23804, PRO:DNx]
Synonyms
EC 2.3.2.27;
Double minute 2 protein;
Oncoprotein Mdm2;
RING-type E3 ubiquitin transferase Mdm2;
p53-binding protein Mdm2
Research
Bioassay Publications (1)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| nutlin-3a | Mus musculus (house mouse) | Ki | 0.0199 | 1 | 1 |
| nvp-cgm097 | Mus musculus (house mouse) | Ki | 0.0659 | 1 | 1 |