Page last updated: 2024-12-09

geranyl acetate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

geranyl acetate: constituted about 90% of the palmarosa oil [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

geranyl acetate : A monoterpenoid that is the acetate ester derivative of geraniol. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID1549026
CHEMBL ID1369384
CHEBI ID5331
CHEBI ID88568
SCHEMBL ID56913
SCHEMBL ID56914
MeSH IDM0395796

Synonyms (132)

Synonym
LS-14126
smr000127400
MLS002152904
bdbm50037025
chebi:5331 ,
[(2e)-3,7-dimethylocta-2,6-dienyl] acetate
33843-18-4
AKOS015837938
wln: 1y & u3yu2ov1-t
3, 6-octadienyl acetate
trans-3,6-octadien-1-ol, acetate
2, 3,7-dimethyl-, acetate, trans-
acetic acid geraniol ester
nci-c54728
2, 3,7-dimethyl-, acetate,(e)-
2, 3,7-dimethyl-, acetate, (e)-
geraniol acetate
nsc-2584
nsc2584
acetic acid, geranyl ester
geranyl acetate, food grade (71% geranyl acetate, 29% citronellyl acetate)
einecs 203-341-5
2,6-octadien-1-ol, 3,7-dimethyl-, acetate, trans-
geranyl acetate (natural)
2,6-dimethyl-2,6-octadiene-8-yl acetate
fema number 2509
hsdb 586
trans-3,7-dimethyl-2,6-octadien-1-ol, acetate
fema no. 2509
ccris 877
ai3-00207
(e)-3,7-dimethyl-2,6-octadien-1-yl acetate
2,6-octadien-1-ol, 3,7-dimethyl-, acetate, (2e)-
geranyl acetate a
(e)-3,7-dimethyl-2,6-octadien-1-ol acetate
nsc 2584
3,7-dimethyl-2,6-octadien-1-ol acetate
trans-2,6-dimethyl-2,6-octadien-8-yl ethanoate
brn 1722815
trans-3,7-dimethyl-2,6-octadien-1-ol acetate
3,7-dimethyl-2-trans, 6-octadienyl acetate
2,6-octadien-1-ol, 3,7-dimethyl-, acetate,(e)-
3,7-dimethyl-2,6-octadien-1-yl ethanoate, trans-
geranoil acetate
3,7-dimethyl-2-trans,6-octadienyl acetate
trans-3,7-dimethyl-2,6-octadien-1-yl acetate
acetic acid, geraniol ester
2,6-octadien-1-ol, 3,7-dimethyl-, acetate
2,6-octadien-1-ol, 3,7-dimethyl-, acetate, (e)-
NCGC00091394-01
C09861
geranyl acetate
105-87-3
geranyl acetate, natural, fcc
geranyl acetate, fcc
geranyl acetate, >=97%
NCGC00091394-02
(2e)-3,7-dimethylocta-2,6-dien-1-yl acetate
3,7-dimethylocta-2,6-dien-1-yl acetate
G0028
NCGC00091394-03
NCGC00091394-04
LMFA07010189
3,7-dimethyl-2e,6-octadienyl acetate
dtxsid0020654 ,
tox21_300355
cas-105-87-3
NCGC00259638-01
dtxcid80654
NCGC00254482-01
tox21_202089
HMS2268G10
geranylacetat
3,7-dimethyloctyl acetate, tetradehydro derivative
1-octanol, 3,7-dimethyl-, 1-acetate, tetradehydro deriv.
einecs 269-749-0
1-octanol, 3,7-dimethyl-, acetate, tetradehydro deriv.
2,6-octadien-1-ol, 3,7-dimethyl-, 1-acetate, (2e)-
3w81yg7p9r ,
unii-3w81yg7p9r
4-02-00-00204 (beilstein handbook reference)
trans-geraniol acetate
ec 203-341-5
CHEMBL1369384
S5091
geranyl ethanoate
geranyl acetate [hsdb]
geranyl acetate [fhfi]
geranyl acetate [fcc]
geranyl acetate [inci]
SCHEMBL56913
SCHEMBL56914
(2e)-3,7-dimethyl-2,6-octadienyl acetate #
meraneine
trans-geranyl acetate
(2e)-geranyl acetate
W-108778
mfcd00015037
trans-3,7-dimethyl-2,6-octadienyl acetate
CHEBI:88568
3,7-dimethyl-2,6-octadien-1-ylacetate
geranyl acetate, primary pharmaceutical reference standard
geranyl acetate, analytical standard
3,7-dimethyl-1-acetate(2e)-2,6-octadien-1-ol
3,7-dimethyl-acetate(2z)-2,6-octadien-1-ol
3,7-dimethyl-acetate(e)-2,6-octadien-1-ol
3,7-dimethyl-acetatetrans-2,6-octadien-1-ol
(2e)-3,7-dimethyl-2,6-octadienyl acetate
fema 2509
3,7-dimethyl-1-acetate(2z)-2,6-octadien-1-ol
cis-3,7-dimethyl-2,6-octadien-1-yl ethanoate
3,7-dimethyl-acetate(2e)-2,6-octadien-1-ol
(z)-3,7-dimethyl-2,6-octadienyl acetate
nerol acetate (6ci)
J-007463
8022-83-1
3,7-dimethyl-2,6-octadien-1-ylacetic acid
(e)-3,7-dimethylocta-2,6-dien-1-yl acetate
Q426437
beta-geranyl acetate
geranyl acetate 100 microg/ml in acetonitrile
2,6-octadien-1-ol, 3,7-dimethyl-, 1-acetate
CCG-266559
D70281
CS-W015698
HY-N7070
acetic acid trans-3,7-dimethyl-oct-2,6-dien-1-yl ester
2,6-octadien-1-ol,3,7-dimethyl-,1-acetate,(2e)-
STARBLD0004670
2,6-octadien-1-ol,3,7-dimethyl-,acetate,(e)-
3,7-dimethyl-2-trans-6-octadienyl acetate
acetyl geraniol

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"9 µg cm(-3) ) was the most toxic compound, followed by citronellyl acetate (16."( Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
Ahn, YJ; Choi, BR; Han, J; Kim, SI; Lee, SG, 2011
)
0.37

Dosage Studied

ExcerptRelevanceReference
" All EOs were repellent, followed a dose-response relationship, and had bioactivity similar to or better than that of commercial compound IR3535."( Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
Caballero-Gallardo, K; Olivero-Verbel, J; Stashenko, EE, 2011
)
0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (4 Product(s))

Product Categories

Product CategoryProducts
Beauty & Personal Care4

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
Attitude Sensitive Skin Shampoo - Soothing & Volumizing - Chamomile -- 16 fl ozAttitudeBeauty & Personal Careglyceryl oleate, floral, citric acid, citric acid, panthenol, triethyl citrate, geranyl acetate, glycerin, linalyl acetate, sodium benzoate2024-11-29 10:47:42
Attitude Super Leaves Nourishing & Strengthening Conditioner -- 32 fl ozAttitudeBeauty & Personal Carefloral, citric acid, citric acid, geranyl acetate, glyceryl stearate, hexyl salicylate, maltodextrin, sodium benzoate, stearyl alcohol2024-11-29 10:47:42
Avalon Organics Scalp Normalizing Shampoo Tea Tree Mint -- 14 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Citric Acid, Terpineol, Benzyl Alcohol, Bisabolol, Camphor, Citric Acid, Citronellol, Decyl Glucoside, Geranyl Acetate, Limonene, Linalyl Acetate, Menthol, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Derma E Anti-Wrinkle Treatment Oil Rosehip & Grape Seed Oils Vitamins A & E -- 2 fl ozDerma EBeauty & Personal Carealpha pinene, bakuchiol, camphor, beta-caryophyllene, citral, eucalyptol, geranyl acetate, retinol2024-11-29 10:47:42

Roles (1)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
acetate esterAny carboxylic ester where the carboxylic acid component is acetic acid.
monoterpenoidAny terpenoid derived from a monoterpene. The term includes compounds in which the C10 skeleton of the parent monoterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (3)

PathwayProteinsCompounds
Olfactory Signaling Pathway8028
geranyl acetate biosynthesis17
Sensory Perception21568
geranyl acetate biosynthesis18

Protein Targets (13)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
15-lipoxygenase, partialHomo sapiens (human)Potency15.84890.012610.691788.5700AID887
TDP1 proteinHomo sapiens (human)Potency23.10930.000811.382244.6684AID686979
AR proteinHomo sapiens (human)Potency28.18380.000221.22318,912.5098AID588515
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency22.38720.011212.4002100.0000AID1030
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency24.33650.001530.607315,848.9004AID1224841; AID1224842
farnesoid X nuclear receptorHomo sapiens (human)Potency0.00110.375827.485161.6524AID588527
estrogen nuclear receptor alphaHomo sapiens (human)Potency1.09620.000229.305416,493.5996AID743075
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency112.20203.548119.542744.6684AID743266
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency26.94540.000323.4451159.6830AID743066
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency29.84930.000627.21521,122.0200AID651741
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)IC50 (µMol)21.20000.45003.42437.5000AID1173731
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)IC50 (µMol)100.00000.00020.606010.0000AID1173737
Transient receptor potential cation channel subfamily M member 8Rattus norvegicus (Norway rat)IC50 (µMol)100.00000.05802.65048.3000AID1173734
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)EC50 (µMol)25.80000.06002.22238.4000AID1173730
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (37)

Processvia Protein(s)Taxonomy
thermoceptionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of transcription by RNA polymerase IITransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
fever generationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
microglial cell activationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
diet induced thermogenesisTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
peptide secretionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of systemic arterial blood pressureTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
lipid metabolic processTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cell surface receptor signaling pathwayTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
positive regulation of cytosolic calcium ion concentrationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
chemosensory behaviorTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of heart rateTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of mitochondrial membrane potentialTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
glutamate secretionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium-mediated signalingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to heatTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
positive regulation of apoptotic processTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
response to peptide hormoneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
positive regulation of nitric oxide biosynthetic processTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
behavioral response to painTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
sensory perception of mechanical stimulusTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
detection of temperature stimulus involved in thermoceptionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
detection of temperature stimulus involved in sensory perception of painTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
detection of chemical stimulus involved in sensory perception of painTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
protein homotetramerizationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
excitatory postsynaptic potentialTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
smooth muscle contraction involved in micturitionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium ion transmembrane transportTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to alkaloidTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to ATPTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to tumor necrosis factorTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to acidic pHTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to temperature stimulusTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of establishment of blood-brain barrierTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium ion import across plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
response to capsazepineTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to nerve growth factor stimulusTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (15)

Processvia Protein(s)Taxonomy
transmembrane signaling receptor activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
extracellular ligand-gated monoatomic ion channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
excitatory extracellular ligand-gated monoatomic ion channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
voltage-gated calcium channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
protein bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calmodulin bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
ATP bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
intracellularly gated calcium channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
chloride channel regulator activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
phosphatidylinositol bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
identical protein bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
metal ion bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
phosphoprotein bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
temperature-gated ion channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (6)

Processvia Protein(s)Taxonomy
plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
external side of plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
dendritic spine membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
neuronal cell bodyTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
postsynaptic membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (42)

Assay IDTitleYearJournalArticle
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1081886Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.2 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081889Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.0002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173729Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to AITC2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1173732Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to ionomycin2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1173737Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1080381Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 2 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1111946Insecticidal activity against acaricide-susceptible female Tetranychus urticae KST (two-spotted spider mite) in kidney bean assessed as mortality in 3 cm disks measured after 24 hr exposure by vapour-phase mortality bioassay2011Pest management science, Dec, Volume: 67, Issue:12
Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
AID1111945Insecticidal activity against chlorfenapyr-resistant female Tetranychus urticae CRT-53 (two-spotted spider mite) in kidney bean assessed as mortality in 3 cm disks measured after 24 hr exposure by vapour-phase mortality bioassay2011Pest management science, Dec, Volume: 67, Issue:12
Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
AID1081892Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.02 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1111942Insecticidal activity against abamectin-resistant female Tetranychus urticae ART-53 (two-spotted spider mite) in kidney bean assessed as mortality in 3 cm disks measured after 24 hr exposure by vapour-phase mortality bioassay2011Pest management science, Dec, Volume: 67, Issue:12
Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
AID1111943Insecticidal activity against pyridaben-resistant female Tetranychus urticae PRT-53 (two-spotted spider mite) in kidney bean assessed as mortality in 3 cm disks measured after 24 hr exposure by vapour-phase mortality bioassay2011Pest management science, Dec, Volume: 67, Issue:12
Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
AID1173734Antagonist activity against rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081893Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173731Antagonist activity against rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081894Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.0002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173733Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081885Lipophilicity, logP of the compound2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1111944Insecticidal activity against fenpropathrin-resistant female Tetranychus urticae FRT-53 (two-spotted spider mite) in kidney bean assessed as mortality in 3 cm disks measured after 24 hr exposure by vapour-phase mortality bioassay2011Pest management science, Dec, Volume: 67, Issue:12
Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
AID1081891Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.2 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081895Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.00002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173736Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081888Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081890Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.00002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081887Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.02 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173730Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1173735Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to ionomycin2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (60)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (1.67)18.7374
1990's0 (0.00)18.2507
2000's18 (30.00)29.6817
2010's29 (48.33)24.3611
2020's12 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 46.42

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index46.42 (24.57)
Research Supply Index4.16 (2.92)
Research Growth Index4.53 (4.65)
Search Engine Demand Index72.10 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (46.42)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other63 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]